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Jeremy G. Vicencio
1st Semester, A.Y. 2011-2012
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Technically, not a part of mitosis
Intensive metabolic activity, cell growth,and cell differentiation occur.
Chromosomes are extended anduncoiled, forming chromatin
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Gap 1 Cell prepares for DNA replication.Ribosomes, tRNA, mRNA and severalenzymes are synthesized and the
cytoplasmic mass increases. The centrioleduplicates in late G or early S phase.
S phase DNA replication takes place
Gap 2 The cell prepares for mitosis.Spindle and aster proteins aresynthesized.
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G1 checkpoint check to see if DNA isdamaged
G2 checkpoint check to see if DNA is
replicated properly M checkpoint spindle assembly
checkpoint, check for alignment of
chromosomes If any of the checks fail, the cell undergoes
apoptosis (programmed cell death)
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A form of cell division resulting in theproduction of two cells, each with thesame chromosome and genetic
complement as the parent cell.
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Spindle formation
Centrioles move toopposite poles
Chromosomes becomevisible
Nuclear membrane
starts to disintegrate
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Period of chromosomemovement
Microtubules of
spindle attach tokinetochore onchromosomes
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Chromosomes line upalong the metaphaseplate
The term is appliedstrictly to thechromosome
configuration aftermigration
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The shortest stage ofmitosis
Sister chromatids of each
chromosome disjoin(separate) from eachother and migrate to
opposite poles Splitting of the
centromeric region
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Nuclear membranereforms
Chromosomes unwind
Commencement ofcytokinesis (cellpinches inward and
forms two daughtercells)
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Interphase Prophase Metaphase Anaphase Telophase
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Animal Cell Plant Cell
Centrosome has 2 centrioles Cytokinesis: CLEAVAGE
Cleavage furrow: shallow
groove near metaphase plate Contractile ring of actin
microfilaments at thecytoplasmic side of furrow
Contraction: pulling ofdrawstrings
Deepening of cleavagefurrow
Pinching of cell into 2
Centrosome has 0 centrioles Cytokinesis: CELL PLATE
Vesicles (with cell wall materials)
from the Golgi move along themicrotubules to middle of cell
Coalescence of vesicles
Cell plate formation Cell wall materials collect at cell
plate Cell plate enlarges surrounding
membrane fuse with plasmamembrane 2 daughter cells
Cell wall between daughter cells
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Growth and development of an organism
Repair of damaged tissues/organs
Reproduction (Asexual)
Genetic continuity