Download - Multivariate Analysis 1 2 Raw material Solution - hovione.com · Raw material dispensing Process Mass ... size distribution 0 5 10 15 20 25 30 0 10 20 30 40 50 60 70 Handheld NIR

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Process Analytical Technologies

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Spray Drying Processes

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Solutionpreparation

SprayDrying

SecondaryDrying

Raw materialdispensing

Process MassSpectroscopy

Process NIR

Process Laser Di�raction

Real-time particlesize distribution

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10

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Handheld NIR

Raw materials identificationand qualification

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-0 .2

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-0 .3 -0 .2 -0 .1 0 0 .1 0 .2

Exhaust gas analysis

Exhaust gas analysis

Drying end-point solid state

characterization

Process NIR

MultivariateAnalysis

FBRMAgglomeration andsuspension stability

Process viscosimetry

Process turbidimetryDissolution end-point

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