Neuronal properties of the Dopaminergic neuron, H-cell
Dopamine ple, Ddc, VMAT, DAT
Neuropeptide receptor: NPFR1 Serotonin receptor: 5-HT1A Glutamate Receptor: Glu-RI
H-cell
tup regulates dopamine biosynthetic and transport genes
pdm2nub
tup
SoxN
D
BH1
HGTX
esg
sim
Pros
Ddc
zfh1
wor
ple
NPFR1
DAT
Glu-RI
5-HT1A
VMAT
Elav
CG31757
SNF4A
tup expression begins late s11
Proteins involved in catacholamine synthesis
Tyrosine L-DOPA Dopamine
TH (ple)
VMAT
Ddc
Catsup
GTP
BH4
GTPCH (Pu)
DAT
Catsup
Ddc is down regulated in tup mutants
Ddc Ab staining
Ddc
Ddc
Ddc/GFP
Ddc/GFP
Ddc enhancer analysis
Grainyhead binds element IDrifter binds Cf1
tup represses NPFR1 expression in abdominal segments
Mapping Antp midline expression
Antp is expressed in mVUMs in T1
Gene regulatory networks in the H-cell
pdm2nub
tup
SoxN
ac/sc
D
BH1
HGTX
esg
sim
Pros
Ddc
zfh1
wor
ple
NPFR1
DAT
Glu-RI
5-HT1A
VMAT
Elav
CG31757
SNF4A