Rumex International Co.
Rumex International LTD.
Ophthalmic Viscosurgical
Devices (OVDs)
Head office:
RUMEX INTERNATIONAL COMPANY 13770 58th Street North, Suite 317
Clearwater, FL 33760, USA
Manufactured: RUMEX INTERNATIONAL Limited 311 Shoreham street Sheefield,
South Yorkshire, S2 4fa UK
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Rumex OVDs
CE Marked November 2011
1.0 ml
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SmartVisc, SmartVisc+
Are viscoelastics based on sodium hyaluronate from biotechnical
fermentation and are free of pyrogenic substances.
SmartVisc 1.6% Sodium hyaluronate
SmartVisc+ 3.0% Sodium hyaluronate
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SmartVisc, SmartVisc+
Will help you maintain the important working space!
• Ability to deepen the anterior and posterior chambers to allow for easier capsulorhexis
and lens implantation
• Excellent tissue manipulation
• Completely transparent to enhance visualisation during cataract and vitreoretinal surgery
• Asrpiration is quick and easy. Additionally, there is less chance for trapped viscoelastic
behind the optic.
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PREREQUISITES FOR VISCOELASTICS DURING
PHACOEMULSIFICATION:
SURGICAL STEPS
PRIMARY FUNCTION
PROPERTIES REQ’D
CATEGORY
Entry into AC Easy entrance for cannula
Medium viscosity @ high shear rate
SmartVisc
Capsulorrhexis Maintain AC High viscosity @ low shear rate
SmartVisc+
Open Capsular Bag Maintain AC & capsular
High viscosity @ low shear rate
SmartVisc+
IOL Implant No resistance Medium viscosity @ medium shear rate
SmartVisc
VES Removal Complete & rapid elimination
High MW & large molecule
SmartVisc SmartVisc+
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SmartVisc 1.6%
Technical data: Sodium Hyaluronate: 1.6 %
Molecular Weight: 1.2 - 2.0 million Daltons
Viscosity: aprox 80.000 mPs
Osmolarity: 270 - 400 mOsm/kg Storage: 2 – 25°C
pH: 6.8 - 7.4
Volume: 1 ml
Shelf life 3 years
Cannula 27 gauge
Soft coating and
protection of endothelial
cells
High cohesion for
easy irrigation / aspiration
Formula:
1 ml contains
Sodium hyaluronate 16.000mg Sodium chloride 8.500 mg Disodium hydrogenphosphate 0.563 mg Sodium dihydrogenphosphate 0.045 mg Water for injection q.s.
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SmartVisc + 3.0%
Technical data: Sodium Hyaluronate: 3.0 %
Molecular Weight: average 1.0 - 1.8 million
Viscosity: aprox 400.000 mPs
Osmolarity: 270 – 400 mOsm/kg
Storage: 2 – 25°C
pH: 6.8 - 7.4
Volume: 1 ml
Shelf life 3 years
Cannula 27 gauge
High Viscosity
Soft coating and
protection of endothelial
cells
High cohesion for
easy irrigation / aspiration
Formula:
1 ml contains
Sodium hyaluronate 30.000mg Sodium chloride 8.500 mg Disodium hydrogenphosphate 0.563 mg Sodium dihydrogenphosphate 0.045 mg Water for injection q.s.
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Features
• Two different viscosities (80&400) can provide Viscoelastic Soft Shell Technique
• Low molecular weight - easy to remove after surgery
• Ultrapure Hyaluronic Acid with highest biocompatibility
• Clear view of posterior capsule during phacoemulsification
• No refrigeration necessary – storage 2-25°
• Volume: 1 ml
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Competitors in the global market
Brand Producer Volume of
Syringe
MW (D) Composition Storage Cohesive Dispersive
Provisc Alcon Labs, USA 0.4;0.55;0.85 2 500 000 1 % NaHa 2-8°C + -
Viscoat Alcon Labs,
USA
0.5 600 000 3 % NaHa,
4 % CDS
2-8°C - +
DisCovisc Alcon Labs,
USA
0.5;1.0 1 650 000 1.7 % NaHa,
4 % CDS
2-8°C + +
Healon AMO, USA 0.4;0.55;0.85 4 000 000 1 % NaHa 2-8°C + -
Healon GV AMO, USA 0.55;0.85 5 000 000 1.4 % NaHa 2-8°C + -
Healon 5 AMO, USA 0.6 4 000 000 2.3% NaHa 2-8°C + +
Amvisc Bausch&Lomb, Inc.,
USA
0.8 2 000 000 1.2 % NaHa 2-8°C + -
Amvisc Plus Bausch&Lomb, Inc.,
USA
0.8 1 500 000 1.6 % NaHa 2-8°C + -
Multivisc BVI, USA 0.6 7 900 000 2.5% NaHa 2-8°C + +
OVD1.2% BVI, USA 1.0 3 000 000 1.2 % NaHa 2-8°C + -
SmartVisc Rumex Int. Ltd, UK 1.0 1 200 000-
2 000 000
1.6% NaHa 2-25 °C + -
SmartVisc+ Rumex Int. Ltd, UK 1.0 1 000 000-
1 800 000
3.0 % NaHa 2-25 °C + -
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Rumex OVDs ‘SUPREME’
CE Marked November 2011
Supreme is a viscoelastic solution of high molecular weight, highly purified grade of hydroxypropyl
methylcellulose 2%, clear, isotonic, sterile, non inflammatory and non-pyrogenic in nature. It is used for
intraocular injection during anterior segment surgery of the eye.
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Product Features
Supreme is a medical device used in the anterior segment surgery of the eye. It has the following unique
characteristics:
•It maintains the depth of the AC of the eye
•It protects the periocular tissues
•Outstanding rheological properties
•Completely transparent
•Simple to remove from the AC
•Totally non antigenic
•Does not contain any proteins likely to cause inflammotary reactions or foreign body reactions
•Does not require refrigeration
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Properties
Molecular Weight 86,000 daltons
Dynamic Viscosity 3000 – 4500 cPs at 27⁰C
pH 6.0 – 7.8
Osmolality 250-350 mosmol/Kg
Volume 2 ml pre-filled glass syringes in double pouch
packing
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Competitors in the global market
Brand Producer Volume of Syringe (ml)
Composition Viscosity (mPas)
MW (D)
Cellugel Alcon Labs., USA)
1.0 2% НРМС 30 000±10 000 300 000
Ocucoat Bausch & Lomb, USA
2.0 2% НРМС 4000 ±1500 92 000
Appavisc Appasamy, India
3.0 2% НРМС 2000 7000
Metilon20 BioTech, India 2.0 2% НРМС 4200 86000
Metilon24 BioTech, India 2.0 2.4% НРМС 4200 86000
Supreme Rumex Inc. Ltd, UK
2.0 2% НРМС 3000-4500 86000
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Head office:
RUMEX INTERNATIONAL COMPANY 13770 58th Street North, Suite 317
Clearwater, FL 33760, USA Tel: +1 (727) 568 0909
Toll Free: +1 (877) 77 RUMEX Fax: +1 (727) 568 0919
Email: [email protected] Webstore: www.rumex.net
Skype: rumex.net
Manufactured: RUMEX INTERNATIONAL Limited 311 Shoreham street Sheefield,
South Yorkshire, S2 4fa UK Tel: +371 6616 3182
Thank you!