Research at Karolinska Institutet2010
Karolinska InstitutetA leading medical university
Dedicated to improving people’s health through research and higher education
The largest centre for medical education and research in Sweden
Research– from molecule to patient
22 departments
600 research groups
1,500 researchers/teachers
including 328 professors
2,000 doctoral students
Traditions and innovations
A few examples of our notable research achievements: SR – sedimentation rate Purification of insulin and heparin Sulphasalazin Antibodies from plasma cells Seldinger catheter Pacemaker Gamma knife Growth hormones
Nanna Svartz, the first female professor at Karolinska Institutet
1937-1957, developed one of the first anti-inflammatory drugs
for rheumatoid arthritis
Swedish Nobel Prize Laureates in Physiology or Medicine – 5 of 8 are from Karolinska Institutet:
1955 Hugo Theorell, - the oxidation enzymes
1967 Ragnar Granit, - the visual processes
1970 Ulf von Euler, - noradrenaline
1982 Sune Bergström & Bengt Samuelsson, - prostaglandins
Scientific publications 2009
About 3,000 original articles and 1,000 other publications were written by researchers at Karolinska Institutet 2009
60 per cent have co-authors outside Sweden
Cited approx 50 per cent more often than the global average (2008)
Research funding accounts for 83 per cent of Karolinska Institutet’s total income
Undergraduate education
Research and doctoraleducation
9
Research revenue 2009 total SEK: 4,057 million (2008: 3,586 million)
Swedish foundations and organisations
16%
Non-Swedish foundations and organisations 3%
EU 6%
Swedish business sector 5%
Non-Swedish business sector
2%
Research councils12%
Other government funding 8%
County and municipal councils
14%
KI-funds 1%
Fin. revenue 0%
Appropriations33%
Februari 2010 10
Research funding
Februari 2010 11
Revenue from EU and USA
Organisation
Board of Research Strategy Research funding and recruitment Research networks Centres of excellence Core facilities Junior faculty Biosafety and ethics Veterinary unit
22 Departments Research Doctoral education
The Stockholms Academic Healthcare System
Cancer Circulation and respiration Endocrinology and metabolism Infection Inflammation and immunology Neuroscience Public and international health Reproduction, growth and development Tissue and motion
Fields of research
Nationally funded Centres of Excellence (Linné)
Centre of Excellence in Developmental Biology for Regenerative Medicine
STARGET – a cancer research network
Center for Research on Inflammation and Cadiovascular Disease, CERIC
The Human Regenerative Map
Linné Centre for Prevention of Breast and Prostate Cancer
Other nationally funded Centres of Excellence
Aging Research Centre Centre for Allergy Research Centre for Health Equity Studies Centre for Infectious Medicine Stockholm Brain Institute Strategic Research Centre for Studies of Integrative
Recognition in the Immune System Structural Genomics Consortium Swedish Brain Power
Core facilities in many areas
KI Biobank Registers Bioinformatics and biostatistics Clinical trial centres Experimental models Expression analysis Genomics Proteomics Visualisation techniques
Strong Research Potential Basic Research and Clinical Research Come Together
Translational Research
Research profile Epidemiology
KI Biobank - core facility for all research contains samples of tissue, blood, serum,
plasma, DNA and other biological specimens
Twin Registry – the largest in the world invaluable resource when correlating
between genes, lifestyle and environment
Medical informatics strong competences in health informatics and biostatistics
Research profile Cellterapy – from stem cell to therapy
Advanced stem cell research Strong clinical expertise in cell therapy and transplantation medicine International leadership in developmental biology Embryonic stem cell lines
Research focus on Parkinson’s disease Spinal cord injuries Diabetes Musculature disease Tissue impairment after cardiac infarction
Research profile Neuroscience
Approx. 20 per cent of all research at Karolinska Institutet is in neuroscience
Three world-leading research centres
Spinal Cord Research Centre Gather about 10 research groups
Stockholm Brain Institute Interdisciplinary research in neuroscience,
psychology and computer science Alzheimer Centre
Translational research in brain aging, dementia and Alzheimer's disease
Leading researchers in virology, bacteriology, parasitology and immunology
Neighbouring the largest infection clinic in Sweden Advanced laboratory facilities Strong international collaborations
Research focus Global infections – HIV, malaria, tuberculosis,
pneumonia Basic immunology, inflammation and infection
medicine
Research profile Infectious diseases and immunology
Basic research in the emergence/origin and development of cancer
Cancer epidemiology Therapy research, e.g. hormone,
immune, and gene therapy Optimizing of radio therapy Clinical trials Quality of life
Research profile Cancer
Reumatoid arthritis Multipel sclerosis Nerve and muscle inflammation Immune defects Autoimmunity Allergies and eczema Asthma and COPD Atherosclerosis
Research profile Inflammatory diseases and allergy
Obesity Advanced research in adult and child obesity Close clinical collaboration
Diabetes Basic research in diabetes
research Treatment research Stem cell research
Cardiovascular research Inflammatory factors Cholesterol metabolism Gender aspects in diagnosis and care
Research profile Metabolic diseases
Aging Research Centre Research from a medical, psychological and
socioeconomic perspective
Dementia Early diagnosis and treatment of cognitive impairment Alzheimer Centre
Swedish Brain Power A national research consortium in
neurodegenerative diseases
Research profile Aging research
Vaccines – HIV, malaria, tuberculosis Reproductive medicine Occupational medicine Psychiatry Geriatrics Humanitarian disaster assistance
Research profile Global health
Partnerships on all continentsResearch focus on poverty and health
Research collaborations
Health care sector Swedish and foreign universities Industrial partners International agreements with
organizations in Europe, North America, Africa and Asia
Offices in China and Singapore
Karolinska Institutet Innovation- from brains to business Promotes the results of biomedical
research to be developed into new products and applications
Provides the means for researchers to develop their research results commercially
Offer project management, funding for patent protection, legal advice and business development
Allows researchers access to an extensive network of contacts within the international pharmaceutical industry
Karolinska Institutet Innovation
Reviewed more that 1 100 academic inventions
More than 40 companies formed since 1996
35 license agreements concluded The system’s portfolio
companies own about 100 patents
30 development project are in its portfolio pipeline
More information: ki.se
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