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The Convergence of Bioinformatics and Medical Informatics
The Convergence of Bioinformatics and Medical Informatics
-- PL Chang, M.D.-- PL Chang, M.D.
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Total Genes – 28939(07-28-2006) – Build 36.1
Total Genes – 28939(07-28-2006) – Build 36.1
Chromosome Genes Chromosome Genes Chromosome Genes
1 2776 9 1207 17 1442
2 1866 10 1094 18 438
3 1473 11 1841 19 1624
4 1164 12 1355 20 717
5 1281 13 556 21 367
6 1528 14 1220 22 756
7 1474 15 961 X 1344
8 1025 16 1108 Y 322
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Protein SynthesisProtein Synthesis
Protein 3D structureProtein 3D structure
38320 Structures (Aug 22, 2006)38320 Structures (Aug 22, 2006)
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Informatics United: Combining Medical Informatics and Bioinformatics
Informatics United: Combining Medical Informatics and Bioinformatics
• The use of image processing techniques for the analysis of
the dynamics of cell nuclei
• The application of medical informatics tools for data
mining in bioinformatics
• Clinical decision support systems based on bioinformatics
have the potential to improve medical diagnostics and lead
to a personalized delivery of healthcare
• The use of image processing techniques for the analysis of
the dynamics of cell nuclei
• The application of medical informatics tools for data
mining in bioinformatics
• Clinical decision support systems based on bioinformatics
have the potential to improve medical diagnostics and lead
to a personalized delivery of healthcare
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Clinical ApplicationsClinical Applications
• Diagnostic tools– Gene chips, protein chips– Early detection of infectious agent, congenital
disorders, susceptibility to disease and, eventually, idiosyncrasy
• Drug Discovery/Development– Gene expression profile– Protein structure and candidate molecules
• Diagnostic tools– Gene chips, protein chips– Early detection of infectious agent, congenital
disorders, susceptibility to disease and, eventually, idiosyncrasy
• Drug Discovery/Development– Gene expression profile– Protein structure and candidate molecules
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Clinical BioinformaticsClinical Bioinformatics
GenomicsGenomics
Personalized medicinePersonalized medicine
Medical informaticsMedical informatics
Bio-decision support systemBio-decision support system
Systems biologySystems biology
Bioinformatics Bioinformatics in cancer researchin cancer research
PharmacogenomicsPharmacogenomics
Structure databasesStructure databases
ProteomicsProteomics
MicroarrayMicroarray
Comparative Comparative genome analysisgenome analysis
Clinical Applications
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CGMH EHR
EHR Clinical Bioinformatics
Genes ProteinsSNPs
Pathways
Diseases電子病歷
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How Will the Medicine of the How Will the Medicine of the 2121stst Century Be Like? Century Be Like?
BioMedical informatics Medical informatics and bioinformatics
Intelligent representation, storage, retrieval and application Data and Text mining
Personalized medicine Diagnosis, treatment, and prognosis ba
sed on bioinformatics
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