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Page 1: Welcome Master’s Degree Orientation May 2, 2013

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Educational Resources

Center for Translational Science Activities

WelcomeMaster’s Degree Orientation

May 2, 2013

Page 2: Welcome Master’s Degree Orientation May 2, 2013

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Agenda• Introductions• CTSA Program Overview• Master’s Degree Requirements• Research Proposal• Scholar/Mentor Relationships• Competencies• Program Evaluations & Outcomes• Questions

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CPXXXXXX-1

CTSA Executive CommitteeRobert A. Rizza, MD

Mayo Clinic Director for ResearchCTSA Director and Principal Investigator

David O. Warner, MDMayo Clinic Associate Director for Clinical/Translational Research

CTSA Associate Director and Co-PI

Scott Kaese / Jane C. WelterAdministrators, Mayo Clinic Research Administrative Services

CTSA Director / Associate Director of Administration

ResearchResourcesS. Khosla, MD

Co-PI and Director

Education Resources

D. Warner, MDCo-PI and Director

External AdvisoryCommittee

Internal AdvisoryCommittee

CTSA Academic AffairsCommittee

CommunityEngagement

P. Targonski, MD PhDCo-PI and Director

03/27/13

Pilot andFeasibility

Research ResourcesReview Panel (RRRP)

ScientificReview Panels

NovelMethodology

Community-Based Research

Networks

Translating Comparative Effectiveness Research into

Practice (TRACER)

Office for Community

EngagedResearch(OCER)

ResearchVolunteer

Resource (RVR)

PredoctoralPrograms

PostdoctoralPrograms

Research Management

Programs

ClinicalResearch

Unit (CRU)Saint Marys

CharltonMobile

MedicalStudent

Programs

CTS Masters and Certificate

ProgramsTranslationalTechnologyCores (TTC)PhD & MD/PhD

Program in CTSKL2 Mentored Career Devel

Program

Scholarly OpportunityAward

RegulatorySupport

Research Ethics

Resource

Consultative, Regulatory, and

Informatics ServicesR. D. Simari, MDCo-PI and Director

Communications

Continuous Professional Development

Program

Study Coordinator

Degreeand Diploma

Programs

SpecializedPhenotyping

Facilities

Study Design and

Biostatistics

BiomedicalInformatics

Res. SubjectAdvocacyServices

Research Information

Center

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Mayo ClinicCenter for Translational Science Activities (CTSA)

• CTSA Research Resources (CRU)

• CTSA Community Engagement

• CTSA Consultative, Regulatory and Informatics Services

• CTSA Education Resources – David O. Warner, MD, DirectorGlenn E. Smith, PhD, LP, Associate Director

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• W. Ray Kim, M.D.• Director, Postdoctoral Programs

• Shawna L. Ehlers, Ph.D., L.P.• Associate Director, Postdoctoral Programs

• Katrin Frimannsdottir, Ph.D.• Director of Program Evaluation

• Karen Weavers – Operations Manager• Tauna Juengers – Operations Coordinator• Anne Bofferding – Curriculum Manager• Linda Wenner –Program Coordinator – Master’s• Linda Ramaker – Program Coordinator- Master’s• Ashley Noelke– Administrative Assistant

Postdoctoral Administrative Staff

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CTSA Master’s Degree Program

Goal:To train independent investigators to perform outstanding extramurally-funded patient-based research.

The Social Contract of Medical Research (discovering and applying knowledge to improve health) is a privilege.

AAMC-GREAT Group

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Master’s Degree Program Expectations• Find time for coursework:

• 1 hr. lecture = 2-4 hours outside work• 1 credit = 48 hours/qtr or 4 hours/week• 3 cr/qtr ~ 12 hours/week• Aligned with research goals

• Accept feedback from mentors/tutors/peers• Learn to identify the important questions• Take charge of your destiny• Submit by deadlines indicated

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Master’s Degree Program Requirements 24 credits - 3.0 GPA

16 required CTSC 8 elective (either CTSC or MGS)

Comprehensive Written Examination (full-day)

Mentored research project resulting in a thesis (2-3 papers – CITE THE GRANT!)

Final Oral Examination (thesis defense) Can be completed in 2-3 years

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Required Coursework5600-Statistics in Clinical Research (2)

5601-Utilizing Statistics in Clinical Research (1)

5610-Introductory Stats Methods II (3)

5690-Critical Appraisal of Statistical Methods in the Medical Literature (1)

5300 & 5310-Clinical Epidemiology I & II (1 ea)

5390- Advanced Applied Epidemiological Methods (2)

5010-Clinical Research Protocol Development (2)

6000-Responsible Conduct of Research (1)

5720-Clinical Trials: Design and Conduct (1)

5020-Regulatory Issues in Clinical Research (1)

Grant Writing Wksp – Nov. 8, 2013

Publication Wksp - Mar. 6, 2014

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Potential Elective Courses• CTSC 5640 Logistic Regression• CTSC 5650 Survival Analysis• MPET 6820 Regenerative Medicine

• CTSC 5080 Eliminating Health Disparities• CTSC 5810 Qualitative Research Design• CTSC 5860 Behavioral Interventions in Clinic Research• CTSC 5870 Social & Behavioral Foundations of Health in HSR

• BMB 8350 Intro to Bioinformatics• CTSC 5140 Epigenetics and Epigenomics• CTSC 5660 Design analysis & App of Bioinformatics

• CTSC 5960 Medical Informatics• CTSC 5760 Medical Decision Making• CTSC 5761 Evidence Based Medicine for Clinical Researchers• CTSC 5910 Economic Evaluation in Health Care• CTSC 5940 Secondary Data Analysis

Clinical Trials

Behavioral

IndividualizedMedicine

Health CareDelivery

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Coursework

• Required: 7 credits beginning either summer or winter quarter

• Mayo Graduate School Course Information• CTSA Annual Course Schedule• Courses available in-person and online• Registration begins one month prior to each

quarter

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Workshops Writing for Biomedical Publications

• March 6, 2014 ~ offered once per year only• Available at all three sites (MCR, MCA, MCF)• Registration Fee - $275 (fee waived)

Write Winning Grants• November 8, 2013 ~ offered once per year only• Available at all three sites (MCR, MCA, MCF)• Registration Fee - $275 (fee waived)

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Research Proposal Packet(due Jan. 2, 2014)

• Includes:1) Cover page (new)2) Cover letter signed by you and your mentor3) Research Proposal Format4) Division research committee approval5) IRB approval

• Reviewed using the Research Proposal Review Criteria• Submission cycle to CTSA approval is twice each year

• January or July only• Early submissions are accepted

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Thesis Advisory Committee (TAC)(due Jan. 2, 2014)

• Minimum of 4 members – 1) Thesis Advisory Committee (TAC) Form

2) Recommended Action on Thesis Protocol Form • TAC and scholar have defined roles and expectations

• Chair - usually primary mentor – only member who can also be co-investigator (exception for statistician)

• Members - need MGS Faculty Privileges (check Catalog)• Oversees progress and quality of research project• Meet every 6 months to review progress of scholar

• Submit summary of Progress Report Meetings to CTSA• Becomes Examining Committee at Thesis Defense

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Master’s Degree Program Form (DPF)(due Jan. 2, 2014)

• Include courses you propose to take to fulfill degree requirements (24 credits total; 17 required)

• Can transfer in up to 6 credits (25%) and may require a taking a test

• Master’s Degree Program Form on Mayo Graduate School Web site

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Comprehensive Written Exam

• Taken after completion of (14 cr):• Protocol Development• Epi I & II• Advanced Applied Epi (III)• Stats I & II• Critical App of Stat Methods (III)• Clinical Trials Design

• Full day exam• August 20, 2013, January 21 or April 15, 2014

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Final Oral Examination –Thesis Defense

• After completion of all course work, approval of DPF, research proposal and TAC and Comprehensive Written Exam

• Follow CTSA and MGS Thesis Guidelines

• Project thesis defense date include on Cover Page. Modifications to date will be communicated through Progress Report Summaries

• Six weeks prior to your anticipated defense date – • Submit thesis draft for CTSA review (allow 1 week)• Find a date/time all TAC members will be present• Allow 3 weeks for TAC to review final draft and prepare

examination questions

• After successful defense, submit Verification of Thesis Corrections and Final thesis to Mayo Graduate School

• Complete Evaluations

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Program Timeline

• January 2, 2014:• Research Proposal Packet (5 items)• Thesis Advisory Packet (2 items)• Degree Program Form (1 item)

• November 8, 2013 – Write Winning Grants Workshop• March 6, 2014 – Publishing Workshop• April 15, 2014 – Comprehensive Written Exam (potential)• July 1, 2014 – Progress Report due

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Scholar and Mentor RelationshipsExpectationsThese are meant as a guide to help facilitate optimal scholar/mentor relationships. Contact CTSA if questions arise.

1) Initial Agreement – at time of application2) Progress Report – submitted 6 months

after research proposal is approved3) Mentoring Effectiveness Assessment

(Scholar & Mentor) – will be requested annually, spring quarter.

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Competencies• Critically evaluate clinical/translational research in the

medical literature• Articulate the ethical & legal responsibilities of an

investigator• Develop feasible and testable hypotheses• Design and conduct a clinical/translational research

project• Write competitive grant proposals• Effectively communicate research results through

publication• Effectively communicate research results through

presentation

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Competencies (cont.)• Articulate and apply appropriate study designs

• Use appropriate biostatistical methods

• Understand the peer-review process

• Ability to navigate the peer-review process for grants and papers

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Program Evaluations & Outcomes

Program Evaluation Activities• Clinical Translational Research Appraisal

(CTRAI) Pre/Post self-assessment – completed in CTSC 5300 Epi I and at end of program

• Mentor Assessments – annual• Course Evaluations• Graduate tracking – annual CVs

Publications, grants, promotions, awards, patents, leadership and professional activities, etc.

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Websites to know

CTSA Education Resourceshttp://ctsa.mayo.edu/education/index.html

• Quarterly Course Schedule• Program Milestones• New course listings• This presentation

Mayo Graduate School http://mayoweb.mayo.edu/mgs/

• Quarterly course listing• Course Registration • Other required forms

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“The research we do today will determine the type of medical and surgical practice

we carry on at the Clinic tomorrow.”

-William J. Mayo, M.D.

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QUESTIONS


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