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VF 57 28%

2110%

LQTS 9 4%

(Kitamura T, et al: N Engl J Med 375:1649-1659, 2016)

Over use

(Childhood fracture)

Landin A (1997)

“---- about 25% of children are injured each year and fractures account for 10-25% of childhood injuries ----- ”

(2002)

6 15

:41.3%

: 26.6%

:18.4%

Landin LA (1997) Sweden, Malmo 8682 0-16 42%, 27%

1950 1979 30 2

Parks MS (2013)

18 4 2

(2008) 13 55,464

(1.9%) (0.9%) 1-2 5-6

(1990) 61 8383

1-2 5-6

(1985) 57 ( , , , , , )

97512

Hagino H (2000) 745

12-13 10-1110

(2005)

1979-1999 2

1979-1999 3

11 15

1981 1990 199941,198

(51 27,666 ), (31 , 13532 ) 2008 7

(1999-2007 )

(2008 )

■ ■ ■ ■ ■

2.77

4.85

3.97

2.82

2.15 1.77

1.48 ■

■ ■

● ● ● ●

● ●

2.27

1.62

2.6

3.15

5.03

6.42

3.88

1.32 1.24

1.65

2.45 2.89 2.92

1.74

1981 1999 1990 2008

1.0

0

3.0

2.0

4.0

5.0

/100 /

▲ ▲

2.39 1.89

1.12

0.69

2.27

0.73

● 1.16

0.42

4.65

1.45

● 2.31

0.36

1981

1999

1990

2008

( )

33.6

21.5

25

33.2

22.6

29

17.2

29.6

4.7

6.5

9.2

7.3

8.1

9.2

22.6

22.6

1981

1999

1990

2008

( )

137.4 132.1 136.2 132.6 161.6 160.2 156.9 155.5

32.9 29.3 31.3 29.1 49.8 48.7 48.0 45.9

:p<0.001

3

VS

n=2976 n=700

3

2010 8696

155/6790( ) = 0.0228 2.28 /100 /

n.s.

(cm)

155.7156.9

19.0 18.9

BMI**

**

65.8%

50.8%

71.8%

54.8%

55.9% 15.9% 10.3% 8.4% 7.8%

44.9% 20.5% 5.5% 29.0%

  n.s.

n.s.n.s. n.s.n.s. n.s.

n.s.n.s.

over use