DNA Structure and Replication

http://www.chemheritage.org/discover/chemistry-in-history/themes/biomolecules/dna/watson-crick-wilkins-franklin.aspx

04/13/2023 2

LINUS PAULING

http://osulibrary.oregonstate.edu/specialcollections/coll/pauling/dna/narrative/page1.html

04/13/2023 3

FRANCIS CRICK AND JAMES WATSON

http://osulibrary.oregonstate.edu/specialcollections/coll/pauling/dna/narrative/page1.html

04/13/2023 4http://osulibrary.oregonstate.edu/specialcollections/coll/pauling/dna/narrative/page1.html

04/13/2023 5

MAURICE WILKINS

ROSALIND FRANKLIN

http://osulibrary.oregonstate.edu/specialcollections/coll/pauling/dna/narrative/page1.html

04/13/2023 6

MAURICE WILKINS

ROSALIND FRANKLIN

http://gandt.blogs.brynmawr.edu/web-papers/web-papers-2/women-in-science/

04/13/2023 7http://osulibrary.oregonstate.edu/specialcollections/coll/pauling/dna/narrative/page1.html

04/13/2023 8

04/13/2023 9

Questions to answer:1. What do you notice about your strand on the LEFT? The

right? Are they identical? Explain.

2. What do you notice about how the RUNGS of the double helix are formed? Do you see patterns? Explain.

3. Label the 5’ and 3’ ends of your molecule. Draw an arrow in the 5’—> 3’ direction on each strand.

04/13/2023 10

04/13/2023 11

ERWIN CHARGAFFBorn: 11-Aug-1905Birthplace: Chernovtsy, UkraineDied: 20-Jun-2002Location of death: New York CityCause of death: unspecified

Gender: MaleRace or Ethnicity: WhiteSexual orientation: StraightOccupation: Biologist, ChemistNationality: United StatesExecutive summary: Biochemist at Columbia University

04/13/2023 12

ERWIN CHARGAFFBorn: 11-Aug-1905Birthplace: Chernovtsy, UkraineDied: 20-Jun-2002Location of death: New York CityCause of death: unspecified

Gender: MaleRace or Ethnicity: WhiteSexual orientation: StraightOccupation: Biologist, ChemistNationality: United StatesExecutive summary: Biochemist at Columbia University

04/13/2023 13

  A T G C

Homo sapiens 31 31.5 19.1 18.4

Drosophila melanogaster

27.3 27.6 22.5 22.5

Zea mays 25.6 25.3 24.5 24.6

Neurospora crassa 23 23.3 27.1 26.6

Escherichia coli 24.6 24.3 25.5 25.6

Bacillus subtilis 28.4 29 21 21.6

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