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APRIL/MAY 2016 • VOL. 15 NO. 2
Integrative Medicine: A Clinician’s Journal
Cognitive Behavioral Therapy and Emotional Freedom Techniques in Reducing Depression and Anxiety Among Adults • Anxiety and Methylenetetrahydrofolate
Reductase Mutation Treated With S-Adenosyl Methionine and Methylated B Vitamins • Bariatric Surgery: Bad to the Bone, Part 2 • Mild Cognitive Impairment,
Neurodegeneration, and Personalized Lifestyle Medicine • Presenters 2016: Elizabeth Frates, MD, and Kristi Hughes, ND • Interview with James Gordon, MD • Editorial: Is
Mold Toxicity Really a Problem for Our Patients? Part I—Respiratory Conditions
Outsmart the Effects of Aging
omax3 Professional Strength with its unique ProResolv™ formulation contains a 4:1 EPA to DHA ratio for a superior inflammatory response7*
• Proven greater reduction of inflammation vs other omega-3 products7*
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• Available only through healthcare professionals
Call 855-978-6615 to make it available from your practiceFor more information, visit www.omax3pro.com or contact us at omax3pro@prevpharm.com
1. Su KP, Matsuoka Y, Pae CU. Omega-3 polyunsaturated fatty acids in prevention of mood and anxiety disorders. Clin Psychopharmacol Neurosci. 2015;13(2):129-137. 2. Crupi R, Marino A, Cuzzocrea S. n-3 fatty acids: role in neurogenesis and neuroplasticity. Curr Med Chem. 2013;20(24):2953-63. 3. Lynch AM, Loane DJ, Minogue AM, et al. Eicosapentaenoic acid confers neuroprotection in the amyloid-beta challenged aged hippocampus. Neurobiol Aging. 2007;28(6):845-855. 4. Heinrichs SC. Dietary omega-3 fatty acid supplementation for optimizing neuronal structure and function. Mol Nutr Food Res. 2010;54(4):447-456. 5. Saunders EF, Reider A, Singh G, Gelenberg AJ, Rapoport SI. Low unesterified:esterified eicosapentaenoic acid (EPA) plasma concentration ratio is associated with bipolar disorder episodes, and omega-3 plasma concentrations are altered by treatment. Bipolar Disord. 2015;17(7):729-742. 6. Sinn N, Milte CM, Street SJ, et al. Effects of n-3 fatty acids, EPA v. DHA, on depressive symptoms, quality of life, memory and executive function in older adults with mild cognitive impairment: a 6-month randomised controlled trial. Br J Nutr. 2012;107(11):1682-93. 7. Data on file, Prevention Pharmaceuticals Inc. New Haven, CT.
omax3 is a registered trademark of Prevention Pharmaceuticals, Inc. ProResolv is a trademark of Prevention Pharmaceuticals, Inc.©2015 Prevention Consumer Health Products. All rights reserved. OMPS007 12/2015
A proper inflammatory response has been shown to improve neurochemical signaling, enhance neuroplasticity, and promote neurogenesis
Balance. Purity. Potency.
®
Professional Strength
Mood1,5,6
Neuroplastic
ity1,2
Neuroprotection3
Anti-infla
mmatory
1
Neurogenesis2,4
Synaptic Plasticity2
Emotional Coping5
Improved Learning4
*These statements have not been evaluated by the US Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
PRVO026 PRO AntiAging AD IVPM FINAL 121715.indd 1 12/17/15 2:17 PM
Outsmart the Effects of Aging
omax3 Professional Strength with its unique ProResolv™ formulation contains a 4:1 EPA to DHA ratio for a superior inflammatory response7*
• Proven greater reduction of inflammation vs other omega-3 products7*
• >93.9% pure omega-3
• Available only through healthcare professionals
Call 855-978-6615 to make it available from your practiceFor more information, visit www.omax3pro.com or contact us at omax3pro@prevpharm.com
1. Su KP, Matsuoka Y, Pae CU. Omega-3 polyunsaturated fatty acids in prevention of mood and anxiety disorders. Clin Psychopharmacol Neurosci. 2015;13(2):129-137. 2. Crupi R, Marino A, Cuzzocrea S. n-3 fatty acids: role in neurogenesis and neuroplasticity. Curr Med Chem. 2013;20(24):2953-63. 3. Lynch AM, Loane DJ, Minogue AM, et al. Eicosapentaenoic acid confers neuroprotection in the amyloid-beta challenged aged hippocampus. Neurobiol Aging. 2007;28(6):845-855. 4. Heinrichs SC. Dietary omega-3 fatty acid supplementation for optimizing neuronal structure and function. Mol Nutr Food Res. 2010;54(4):447-456. 5. Saunders EF, Reider A, Singh G, Gelenberg AJ, Rapoport SI. Low unesterified:esterified eicosapentaenoic acid (EPA) plasma concentration ratio is associated with bipolar disorder episodes, and omega-3 plasma concentrations are altered by treatment. Bipolar Disord. 2015;17(7):729-742. 6. Sinn N, Milte CM, Street SJ, et al. Effects of n-3 fatty acids, EPA v. DHA, on depressive symptoms, quality of life, memory and executive function in older adults with mild cognitive impairment: a 6-month randomised controlled trial. Br J Nutr. 2012;107(11):1682-93. 7. Data on file, Prevention Pharmaceuticals Inc. New Haven, CT.
omax3 is a registered trademark of Prevention Pharmaceuticals, Inc. ProResolv is a trademark of Prevention Pharmaceuticals, Inc.©2015 Prevention Consumer Health Products. All rights reserved. OMPS007 12/2015
A proper inflammatory response has been shown to improve neurochemical signaling, enhance neuroplasticity, and promote neurogenesis
Balance. Purity. Potency.
®
Professional Strength
Mood1,5,6
Neuroplastic
ity1,2
Neuroprotection3
Anti-infla
mmatory
1
Neurogenesis2,4
Synaptic Plasticity2
Emotional Coping5
Improved Learning4
*These statements have not been evaluated by the US Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
PRVO026 PRO AntiAging AD IVPM FINAL 121715.indd 1 12/17/15 2:17 PM
Tel: 805.693.1802 • Fax: 805.693.1806 • CustomerService@ResearchedNutritionals.comwww.ResearchedNutritionals.com | Available only through healthcare professionals
CALL 800.755.3402
*These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure or prevent any disease.
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Tel: 805.693.1802 • Fax: 805.693.1806 • CustomerService@ResearchedNutritionals.comwww.ResearchedNutritionals.com | Available only through healthcare professionals
CALL 800.755.3402
*These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure or prevent any disease.
Joseph Burrascano Jr., MD“Due to the research basis of these formulations, I think these products would be an important part of a practitioner’s arsenal.”
Healthy Cytokine SupportCytoQuel™ has been developed to promote healthy cytokine activity. Based on the latest published research, CytoQuel™ offers doctors a valuable new tool in the quest for healthy inflammation levels.
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Integrative Medicine • Vol. 15, No. 2 • April 2016 3Table of Contents
6 Is Mold Toxicity Really a Problem for Our Patients? Part I—Respiratory Conditions Joseph Pizzorno, ND, Editor in Chief
12 Mild Cognitive Impairment, Neurodegeneration, and Personalized Lifestyle Medicine Jeffrey Bland, PhD, Associate Editor
64 The Circle Game Bill Benda, MD, Associate Editor
16 The Leadership of the Naturopathic Profession in the Emergence of Integrative and Functional Medicine … plus more John Weeks
27 The Effectiveness of Cognitive Behavioral Therapy and Emotional Freedom Techniques in Reducing Depression and Anxiety Among Adults: A Pilot Study Hannah Chatwin, MClinPsych; Peta Stapleton, PhD; Brett Porter, EFT Practitioner; Sharon Devine, MClinPsych; Terri Sheldon, BA(Hons)
48 Anxiety and Methylenetetrahydrofolate Reductase Mutation Treated With S-Adenosyl Methionine and Methylated B Vitamins Shanna Anderson, BA; Jacob Panka, BA; Robin Rakobitsch, BA; Kaitlin Tyre, BS; Kerry Pulliam, MD
35 Bariatric Surgery: Bad to the Bone, Part 2 Lara Pizzorno, MDiv, MA, LMT
20 Elizabeth Frates, MD, and Kristi Hughes, ND: Creating Strategies for Prescribing Effective Lifestyle Modifications Interview by Craig Gustafson
54 James Gordon, MD: The Potential of Mind-Body Self Care to Free the World From the Effects of Trauma Interview by Craig Gustafson
62 Conference Calendar
EDITORIALS
COMMENTARY
VIEWPOINTS
Integrative Medicine: A Clinician’s Journalwww.imjournal.com
April/May 2016 • Vol. 15 No. 2
REVIEW ARTICLE
PRESENTERS 2016
EPTHECA
CASE REPORT
PILOT STUDY