Post on 05-Feb-2018
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• Exceptional Quality
• Sensibly Priced
Lux Cellulose-1Guaranteed Alternative to CHIRALCEL® OD-H®
SIMPLIFIED CHIRAL SEPARATIONS
Proven universal selector •
Available in 3 µm, 5 µm, and 20 µm •
Sensibly priced•
Stable up to 300 bar (4,350 psi)•
Easy solvent switching •
H
HH
H
HC
C
H
HH
C
C
H
HH
H
O
O
C
H
N
O
HH
C
C
C
C
C
CC
H
H
H
H
O
O
O
N
C
O
H
N
HH
H
HH
C
C
H
O
H
Lux Cellulose-1Cellulose tris(3,5-dimethylphenylcarbamate)
Meet the Rest of the Lux Family!
The Lux line of CSPs offers 5 complementary selectivities
© 2010 Phenomenex, Inc. All rights reserved.
Advantages of using Lux Cellulose-1
This dimethyl cellulose selector is famous around the world for its ability to separate aromatic, conjugated, and other challenging chiral compounds.
C-1 C-2 A-2
Cellulose Backbone Cellulose Backbone
C-3
Cellulose Backbone
C-4
Cellulose Backbone Amylose Backbone
H
H HC
H
H
HH
H
CC
H
Cl
H
H C H
C
Cl
O
HH
H
Cl
H
HC
H
Lux Cellulose-2cellulose tris(3-chloro-4- methylphenylcarbamate)
Chlorinated Cellulose
C-1 C-2 A-2
Cellulose Backbone Cellulose Backbone
C-3
Cellulose Backbone
C-4
Cellulose Backbone Amylose Backbone
H
H HC
H
H
HH
H
CC
H
Cl
H
H C H
C
Cl
O
HH
H
Cl
H
HC
H
Cellulose Ester
Lux Cellulose-3cellulose tris(4-methylbenzoate)
C-1 C-2 A-2
Cellulose Backbone Cellulose Backbone
C-3
Cellulose Backbone
C-4
Cellulose Backbone Amylose Backbone
H
H HC
H
H
HH
H
CC
H
Cl
H
H C H
C
Cl
O
HH
H
Cl
H
HC
H
Chlorinated Cellulose
Lux Cellulose-4cellulose tris(4-chloro-3- methylphenylcarbamate)C-1 C-2 A-2
Cellulose Backbone Cellulose Backbone
C-3
Cellulose Backbone
C-4
Cellulose Backbone Amylose Backbone
H
H HC
H
H
HH
H
CC
H
Cl
H
H C H
C
Cl
O
HH
H
Cl
H
HC
H
Lux Amylose-2amylose tris(5-chloro-2- methylphenylcarbamate)
Chlorinated Amylose
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™
3
Ambucetamide
Nomifensine
0
17412
2 4
1
2
6 8 min
0 2
2
17414
4 6 81
1
3 5 7 9 min
2
2
431
1
0 5
17422
min
0 1 2
21
3 4 5 min
17423
0 2 4
1 2
6 min
17454
0 2
21
4 51 3 min
17456
Conditions for both columns:
Dimensions: 250 x 4.6 mmMobile Phase: 0.1 % Diethylamine in Methanol /
0.1 % Diethylamine in Isopropanol (90:10)Flow Rate: 1 mL/min
Temperature: AmbientDetection: UV @ 220 nm
Conditions for both columns:
Dimensions: 250 x 4.6 mmMobile Phase: 0.1 % Diethylamine in Acetonitrile /
0.1 % Diethylamine in Isopropanol (95:5)Flow Rate: 1 mL/min
Temperature: AmbientDetection: UV @ 220 nm
Conditions for both columns:
Dimensions: 250 x 4.6 mmMobile Phase: 0.1 % Diethylamine in Acetonitrile /
0.1 % Diethylamine in Isopropanol (95:5)Flow Rate: 1 mL/min
Temperature: AmbientDetection: UV @ 220 nm
Lux 5 µm Cellulose-1a = 2.09
Lux 5 µm Cellulose-1a = 1.38
*CHIRALCEL® 5 µm OD-H®
a = 1.83
*CHIRALCEL® 5 µm OD-H®
a = 1.18
Lux 5 µm Cellulose-1a = 1.20
*CHIRALCEL® 5 µm OD-H®
a = 1.11
O
OH2N
N
O
H
OH
H3COCH3
CH3NH
CH3
NH2
H
N
Guaranteed Alternative to CHIRALCEL® OD-H®
Ap
p ID
174
12A
pp
ID 1
7422
Ap
p ID
174
54A
pp
ID 1
7414
Ap
p ID
174
23A
pp
ID 1
7456
Metoprolol
Phenomenex l WEB: www.phenomenex.com
SIMPLIFIED CHIRAL SEPARATIONS
If Lux analytical columns (≤ 4.6 mm ID) do not provide at least an equivalent or better separation as compared to a competing column of the same particle size, similar phase and dimensions, send in your comparative data within 45 days and keep the Lux column for FREE.
4
0 1 2 3 4 5 6 min
1
17321
2
0 2
2
1
4 6 min
17322
Conditions for both columns:
Dimensions: 250 x 4.6 mmMobile Phase: 0.1 % Diethylamine in Hexane /
0.1 % Diethylamine in Isopropanol (90:10) Flow Rate: 1 mL/min
Temperature: AmbientDetection: UV @ 220 nm
Lux 5 µm Cellulose-1a = 1.09
*CHIRALCEL® 5 µm OD-H®
a = 1.07
N
O
H3CCH3
0 2 3
2
1
41 5 6 min
17404
0 2 3 51
2
1
4 6 min
17405
0 2
21
4 6 81 3 5 7 min
17415
0 2
2
4 6 81
1
3 5 7 min
17417
Conditions for both columns:
Dimensions: 250 x 4.6 mmMobile Phase: 0.1 % Diethylamine in Acetonitrile /
0.1 % Diethylamine in Isopropanol (95:5)Flow Rate: 1 mL/min
Temperature: AmbientDetection: UV @ 220 nm
Conditions for both columns:
Dimensions: 250 x 4.6 mmMobile Phase: 0.1 % Diethylamine in Methanol /
0.1 % Diethylamine in Isopropanol (90:10)Flow Rate: 1 mL/min
Temperature: AmbientDetection: UV @ 220 nm
Lux 5 µm Cellulose-1a = 1.31
*CHIRALCEL® 5 µm OD-H®
a = 1.20
Lux 5 µm Cellulose-1a = 1.39
*CHIRALCEL® 5 µm OD-H®
a = 1.28
OH
H3C
Cl
O
N
N
Specialized Coating Process and Expert Packing Provides Optimal Column Performance.
Cl
O
N
O
Ap
p ID
173
21A
pp
ID 1
7404
Ap
p ID
174
15A
pp
ID 1
7322
Ap
p ID
174
05A
pp
ID 1
7417
Tolperisone
Metofoline
Our robust coating and packing process allows you to enjoy increased loading capacity, column reproducibility, and exceptional enantiomeric resolution. Achieve the optimal efficiencies you desire without sacrificing chiral recognition abilities.
Temazepam
Phenomenex l WEB: www.phenomenex.com
™
5
Conditions for both columns:
Dimensions: 250 x 4.6 mmMobile Phase: 0.1 % Diethylamine in Methanol /
0.1 % Diethylamine in Isopropanol (90:10)Flow Rate: 1 mL/min
Temperature: AmbientDetection: UV @ 220 nm
Extreme Stability and Separating Power under SFC Conditions.
18855
0 2
2
1
4 6 8 10 12 14 16 18 20 22 24 min
0 2
2
1
19098
4 6 8 10 12 14 16 18 20 22 24 min
0 2
2
1
19100
4 6 8 10 12 14 16 18 20 22 24 26 28 min
0 2
1
2
4 6 8 10 12 14 16 18 20 22 24 26 28 min
19101
Atenolol
Conditions for both columns:
Dimensions: 250 x 4.6 mmMobile Phase: 0.1 % Diethylamine in Methanol /
Carbon Dioxide (20:80)Flow Rate: 2.5 mL/min
Temperature: 35 °CDetection: Diode Array Detector
Conditions for both columns:
Dimensions: 250 x 4.6 mmMobile Phase: 0.1 % Diethylamine in Methanol /
Carbon Dioxide (15:85)Flow Rate: 2.5 mL/min
Temperature: 35 °CDetection: Diode Array Detector
Bifonazole
Lux 5 µm Cellulose-1a = 1.08
Lux 5 µm Cellulose-1a = 1.97
*CHIRALCEL® 5 µm OD-H®
a = 1.02
*CHIRALCEL® 5 µm OD-H®
a = 1.64
N
N
O
O
OH
HN
H2N
CH3
CH3
H
Ap
p ID
191
00A
pp
ID 1
8855
Ap
p ID
191
01A
pp
ID 1
9098
Never fear crushed media or loss in efficiency again. With a pressure stability up to 300 bar (4,350 psi), you can feel confident about running at high operating pressures (if necessary). Lux media is SFC approved and versatile enough to satisfy all of your chiral separation needs.
Phenomenex l WEB: www.phenomenex.com
SIMPLIFIED CHIRAL SEPARATIONS
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Easy Chiral Method Development
Chiral Phase Screening•
Method Optimization•
Method Re-Validation•
Scale-Up Services•
On-Site Training•
For more information on our services or to begin a project, please contact your local Phenomenex chiral expert or email us at: phenologics@phenomenex.com
You can also visit us on the web: www.phenomenex.com/phenologics
*Based on screening 233 compounds on all five Lux Phases
Chiral Screening and Separation ServicesHPLC | SFC | Preparative | Training
Phenomenex l WEB: www.phenomenex.com
Resolve 92 % of your enantiomers with five complementary Lux™ phases.*
To get you started, we have outlined a simple strategy for screening CSPs under HPLC and SFC conditions in our chiral method development solutions poster.
Call or go online today to create your own custom screening kit or to request a chiral method development solutions poster at www.phenomenex.com/info/lux
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Ordering Information
*SecurityGuard Analytical Cartridges require holder, Part No. : KJ0-4282‡SemiPrep SecurityGuard Cartridges require holder, Part No. : AJ0-7220
**PREP SecurityGuard Cartridges require holder, Part No. : AJ0-8223+PREP SecurityGuard Cartridges require holder, Part No. : AJ0-8277
Phenomenex l WEB: www.phenomenex.com
SIMPLIFIED CHIRAL SEPARATIONS
If Lux analytical columns (≤ 4.6 mm ID) do not provide at least an equivalent or better separation as compared to a competing column of the same particle size, similar phase and dimensions, send in your comparative data within 45 days and keep the Lux column for FREE.
Column Performance Check StandardPart No. Description Unit Price
AL0-8412 Chiral Test Mix No. 5 (Lux) ea
3 µm Method Screening Kits (save 10 % when purchased as a kit)
50 x 4.6 mm 250 x 4.6 mm
Screening Kit KH0-8483 KH0-8482Kit contains one column of each phase.
5 µm Semi-Prep Columns (mm)SecurityGuard™ Cartridges (mm)
150 x 10.0 250 x 10.0 10 x 10.0‡
Phases /3pk
Cellulose-1 00F-4459-N0 00G-4459-N0 AJ0-8404
Cellulose-2 00F-4457-N0 00G-4457-N0 AJ0-8399
Cellulose-3 00F-4493-N0 00G-4493-N0 AJ0-8623
Cellulose-4 00F-4491-N0 00G-4491-N0 AJ0-8628
Amylose-2 00F-4472-N0 00G-4472-N0 AJ0-8472
for ID: 9–16 mm
5 µm Axia™ Packed Preparative Columns (mm) SecurityGuard™ Cartridges (mm)150 x 21.2 250 x 21.2 250 x 30 250 x 50 15 x 21.2** 15 x 30.0+
Phases /ea /ea
Cellulose-1 00F-4459-P0-AX 00G-4459-P0-AX 00G-4459-U0-AX 00G-4459-V0-AX AJ0-8405 AJ0-8406
Cellulose-2 00F-4457-P0-AX 00G-4457-P0-AX 00G-4457-U0-AX 00G-4457-V0-AX AJ0-8400 AJ0-8401
Cellulose-3 00F-4493-P0-AX 00G-4493-P0-AX 00G-4493-U0-AX 00G-4493-V0-AX AJ0-8624 AJ0-8625
Cellulose-4 00F-4491-P0-AX 00G-4491-P0-AX 00G-4491-U0-AX 00G-4491-V0-AX AJ0-8629 AJ0-8630
Amylose-2 00F-4472-P0-AX 00G-4472-P0-AX 00G-4472-U0-AX 00G-4472-V0-AX AJ0-8473 AJ0-8474
for ID: 18 –29 mm 30–49 mm
3 µm Analytical Columns (mm) SecurityGuard™ Cartridges (mm)50 x 2.0 150 x 2.0 50 x 4.6 100 x 4.6 150 x 4.6 250 x 4.6 4 x 2.0* 4 x 3.0*
Phases /10pk /10pk
Cellulose-1 00B-4458-B0 00F-4458-B0 00B-4458-E0 00D-4458-E0 00F-4458-E0 00G-4458-E0 AJ0-8402 AJ0-8403
Cellulose-2 00B-4456-B0 00F-4456-B0 00B-4456-E0 00D-4456-E0 00F-4456-E0 00G-4456-E0 AJ0-8398 AJ0-8366
Cellulose-3 00B-4492-B0 00F-4492-B0 00B-4492-E0 00D-4492-E0 00F-4492-E0 00G-4492-E0 AJ0-8621 AJ0-8622
Cellulose-4 00B-4490-B0 00F-4490-B0 00B-4490-E0 00D-4490-E0 00F-4490-E0 00G-4490-E0 AJ0-8626 AJ0-8627
Amylose-2 00B-4471-B0 00F-4471-B0 00B-4471-E0 00D-4471-E0 00F-4471-E0 00G-4471-E0 AJ0-8471 AJ0-8470
for ID: 2.0 –3.0 mm 3.2–8.0 mm
5 µm Analytical Columns (mm) SecurityGuard™ Cartridges (mm)50 x 2.0 50 x 4.6 100 x 4.6 150 x 4.6 250 x 4.6 4 x 2.0* 4 x 3.0*
Phases /10pk /10pk
Cellulose-1 00B-4459-B0 00B-4459-E0 00D-4459-E0 00F-4459-E0 00G-4459-E0 AJ0-8402 AJ0-8403
Cellulose-2 00B-4457-B0 00B-4457-E0 00D-4457-E0 00F-4457-E0 00G-4457-E0 AJ0-8398 AJ0-8366
Cellulose-3 00B-4493-B0 00B-4493-E0 00D-4493-E0 00F-4493-E0 00G-4493-E0 AJ0-8621 AJ0-8622
Cellulose-4 00B-4491-B0 00B-4491-E0 00D-4491-E0 00F-4491-E0 00G-4491-E0 AJ0-8626 AJ0-8627
Amylose-2 00B-4472-B0 00B-4472-E0 00D-4472-E0 00F-4472-E0 00G-4472-E0 AJ0-8471 AJ0-8470
for ID: 2.0–3.0 mm 3.2–8.0 mm
Terms and Conditions Subject to Phenomenex Standard Terms & Conditions, which may be viewed at www.phenomenex.com/TermsAndConditions.
Trademarks CHIRALCEL and OD-H are registered trademarks of DAICEL Chemical Industries, Ltd. Axia, Lux, and SecurityGuard are trademarks of Phenomenex, Inc.
Disclaimer Comparative separations may not be representative of all applications. Columns used for comparison were manufactured by DAICEL Chemical Industries, Ltd. Phenomenex is not affiliated with DAICEL Chemical Industries.
© 2010 Phenomenex, Inc. All rights reserved.
20 µm Bulk Media100 g 1 kg
Phases
Cellulose-1 04G-4473 04K-4473
Cellulose-2 04G-4464 04K-4464
Amylose-2 ∆ ∆
∆Please inquire for 20 µm Lux Amylose-2, Cellulose-3 or Cellulose-4 media.
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