•Objectives

•Division of Work

•Background

•Mirror Fabrication

•Cavity Fabrication

•Biomaterials

•Sample Preparation

•Test Procedure

•Results

•Timeline

•Future Work

•Conclusion

To design and build a proof of concept experiment for a novel high sensitivity biosensor based on a Fabry-Perot cavity

Division of WorkDivision of Work• Initial Design Simulations and Evaluation

o Sims Approach Research and Evaluationo MS Excel

• Biomaterial Sample Prep

• Fabricate device for testingo Obtain materialso Assemble the prototypes

• Build test setup

Write test programs to acquire data◦ Control instruments◦ Demodulate the signal◦ Graph results◦ Automate the testing/graphing procedure

Rui:

Jarrod:

Emile:

Important Properties of a F-P Cavity:

• Free Spectral Range:

• Finesse:

• Resonant Condition: where m=1,2,3 …

mm

nL 1

2

2

R

RF

1

R=.3

R=.5 R=.9

λm λm+1λm-1

BackgroundBackground

nLm m 2

Glass Glass Glass Glass

Glass Glass

Mirrors

Glass

Glass

Air

Glass Glass Glass Glass

Glass Glass

Glass

Glass

Air

BIO Material

Glass Glass Glass Glass Glass

Glass Glass

AirAir

Mirror Mirror

BIO Material

Glass Glass Glass Glass Glass

Glass Glass

AirAir

Mirror Mirror

Mirror FabricationMirror FabricationMirrors will be formed using AJA 7000 Sputtering System

• Many metal coatings available• Au, Ag, Al, Ti, Ni, Cr• Low pressure for high quality films• Precise control of the thickness

Mirror FabricationMirror Fabrication

GlassTitanium

Gold

Mirror TestingMirror Testing

Transmission @ 1.55µm

Glass: 87%

10Å Ti / 40Å Au: 47%

10Å Ti / 70Å Au: 18%

10Å Ti / 40Å Au

10Å Ti / 70Å Au

Cavity FabricationCavity Fabrication

Cavity FabricationCavity Fabrication

Cavity FabricationCavity Fabrication

Verification of CavityVerification of Cavity

Cavity FabricationCavity Fabrication

Reason for Failure:•Only 150Å of gold

• Missing the “sticking layer”

Solution:• Use a sticking layer

• Can be Ni, Ti, Cr

•Biomaterials in cavities:•Protein G•IgG•Fab

•Same Concentration for all experimental setups

Coating BiomaterialsCoating Biomaterials

Glass

Protein G

IgG

Glass Protein GIgG

Gold

PC/Matlab

GPIB/IEEE Cable

Micron Optics si720

Optical Sensing Analyzer

Test Setup

Single Mode Fiber

Testing Block Diagram

Power Input Detected light

Start

Folder/File location to save data

Start/Stop Wavelengths

Figure

Run Matlab GUI

Locate File/Folder Locationto save data

Start/Stop Wavelengths

Start

-Set the Start/Stop Wavelengths on Optical Analyzer

-Start Sweeping through wavelengths

-Get data results and save them in specified folder

Show Results

30-Jan

6-Feb

13-Feb

20-Feb

27-Feb

5-Mar

12-Mar

19-Mar

26-Mar

2-Apr

9-Apr

16-Apr

23-Apr

30-Apr

7-May

14-May

Literature Review

Simulations

Prepare for Report I and Presentartion

Procure Raw Materials

Form Mirrors and Assemble Cavity

Write Code for Testing

Build Test Set up and Preform Experiments

Prepare for Report II and Presentation

Data Analysis / Retest

Prepare Final Report and Presentation

Future WorkFuture Work

1. Multi-channel Fabry-Perot cavity

waveguide structure.

Silicon Substrate

Silicon Waveguide

Multiple Channels

Mirrored Ends

Silicon substrate

Future WorkFuture Work1. Multi-channel Fabry-Perot cavity

waveguide structure

2. Integrated with microfluidics Biomaterials

Fluid Cavity

PolymerCap

Waveguide with Waveguide with microfluidicsmicrofluidicsBenefits:• Reduced device size

• Can create more channels for biomaterials

• Enables mass production

• Uniform device sizeBiomaterials

• Fabrication of Cavities is feasible

• Goal has been reached

• Introduce mirror reflectivity as a variable when testing

ConclusionConclusion