Past, Present, and Future Perspectives on REVES, and “My...

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Dr. Sandy ReynoldsGeorge Myers Memorial Lecture,

REVES 28Vienna, Austria

Past, Present, and Future Perspectives on REVES, and “My Brilliant Career”

Agenda

1. The PastREVES and My Career – vaguely, 1990 through 2015

2. The PresentThe State of Health in the World (largely according to OECD and WHO)

3. The FutureFuture Health Concerns

Who Ruled the World? 1990Margaret Thatcher

Francois Mitterand

Li Peng Helmut Kohl

Mikhail Gorbachev

Toshiki Kaifu

George H.W. Bush

Who Rules The World: Now

David Cameron

FrancoisHollande Vladimir Putin

Shinzo Abe

Le Keqiang

Angela Merkel

Barack Obama

Well, some things never change

1990

NOW

And In the Future?

In the Beginning:1989-1990■ REVES

– 1990 Geneva– 1990 Durham

■ MOI!

– Still in Banking in New England

26,09

21,74

17,39

13,04

4,35

13,044,35

Methods DefDisab Xnatldef Single HE Mult HE PsyCog HlthTrends

Then 1991-1993

■ REVES– 1991 Leiden– 1992 Ottawa– 1993?

■ MOI– Fall, 1991 – USC!

Then 1994-5!

■ REVES– 1994 Canberra– 1995 Chicago

■ MOI – – started working

with Eileen! 1994– 1995 – PhD

1996

■ REVES– 1996 – Rome!

■ MOI –– Graduation and– USF!!

1997- 2000

■ REVES– 1997 Tokyo– 1999 London– 2000 Los Angeles

■ MOI– Publish, Publish,

Publish■ My own

Guardianship Research

■ With Eileen and Saito

2001 - 2003

■ REVES– 2001 Vancouver– 2002 Hammamet– 2003 Guadalajara

■ MOI– Publish, Publish,

Publish■ My own

Guardianship Research

■ With Eileen and Saito

– 2002 – TENURE!!!– And my first REVES

in 2003!

2004 - 2006

■ REVES– 2004 Bruges– 2005 Beijing– 2006 Amsterdam

■ MOI – Sabbatical with

Eileen– Publish, Publish,

Publish■ Obesity and Active

Life Expectancy■ With Eileen and

Saito– And Spin-offs– Treasurer of GSA!!

2007 – REVES and I COINCIDE:St. Petersburg

Beach, Florida

2007 – REVES and I COINCIDEBernard

2008 - 2011

■ REVES – 2008 Manila– 2009 Copenhagen– 2010 Havana!– 2011 Paris!!!!!

■ MOI– Publish, Publish– Administrative Work– Finished up as GSA

Treasurer – 2010– Master Chorale of Tampa

BayME

2012 - 2014

■ REVES– 2012 Taipei– 2013 Austin– 2014 Edinburgh

■ MOI

– Publish, Publish– Administrative Work– Master Chorale of Tampa

Bay

2015-2016

■ REVES -– 2015 Singapore– 2016 Vienna

ME - RETIREMENT!!!

REVES Agendas, 1990 - 2014

And My Career

0

2

4

6

8

10

12

14

16

18

1990 1991 1992 1994 1995 1996 1997 1998 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015

Topic Trends – Beginning, Middle and End

0,0

5,0

10,0

15,0

20,0

25,0

1990-1994 2000-2004 2010-2014

Methods Definition HlthExp CauseCoV HlthTrend Macro Mortality Diversity

Meanwhile, what’s been going on in the World?

The Regions

30

40

50

60

70

80

90

1950 1975 2009 2025 2050

Life Expectancy at Birth - MALESAfrica Asia Europe LAC N America Oceania

WHO Global Database: Indicators

Life Expectancy at Birth: Global, High and Low Income Countries, Men and Women

Source: WHO, Global Health Observatory Data Repository, Life Expectancy, 2016

51 53

61

71 7276

40

50

60

70

80

90

1990 2000 2013

Men

Low Income High Income

54 55

64

78 80 82

40

50

60

70

80

90

1990 2000 2013

Women

Low Income High Income

Specific Countries: LE at Birth, 1970 and 2011

78,781,1

82,7

73,5

82,0

74,2

69,0

78,0

82,2 81,9

53,0

81,8

50,0

55,0

60,0

65,0

70,0

75,0

80,0

85,0

1970 2011

Death Rates– All Causes (rates per 100,000 pop.)

Source: European Health for All Database

873,7

689,4739,9

1046,8

1192,6

823,9

938,7

583,1

484,6553,1

893,1

1134,0

536,9

731,9

0,0

200,0

400,0

600,0

800,0

1000,0

1200,0

1400,0

Denmark France Greece Lithuania Russia UK US

1990 2011-2013

Death Rates– Circulatory Diseases

Source: European Health for All Database

363,6

205,6

370,8

586,0

668,7

365,2387,1

135,9107,2

217,6

451,1

613,3

140,7

206,0

0,0

100,0

200,0

300,0

400,0

500,0

600,0

700,0

800,0

Denmark France Greece Lithuania Russia UK US

1990 2011-2013

Death Rates– Cancer

Source: European Health for All Database

231,8

201,2

158,9

193,4201,5

220,5 216,0

185,4

158,6152,7

182,2 173,4165,8 163,2

0,0

50,0

100,0

150,0

200,0

250,0

Denmark France Greece Lithuania Russia UK US

1990 2011-2013

Death Rates– Respiratory System

Source: European Health for All Database

63,4

43,839,4

47,5

63,2

85,0

74,0

59,2

26,3

47,3

27,3

44,7

70,1

58,0

0,0

10,0

20,0

30,0

40,0

50,0

60,0

70,0

80,0

90,0

Denmark France Greece Lithuania Russia UK US

1990 2011-2013

Death Rates– Diabetes

Source: European Health for All Database

12,2

8,0 7,15,6

6,5

10,4

20,7

14,6

9,1

5,66,9

5,2 5,3

31,2

0,0

5,0

10,0

15,0

20,0

25,0

30,0

35,0

Denmark France Greece Lithuania Russia UK US

1990 2011-2013

Death Rates– External Causes

Source: European Health for All Database

61,7

72,0

40,4

122,7

135,7

33,4 36,328,9

42,2

26,1

109,2

126,8

27,5

39,4

0,0

20,0

40,0

60,0

80,0

100,0

120,0

140,0

160,0

Denmark France Greece Lithuania Russia UK US

1990 2011-2013

Death Rates from Suicide, Selected Countries, 2011

12,5

6,7

20,9

38,3

10,1

4,8

22,5

14,316,2

11,7

7,4

0

5

10

15

20

25

30

35

40

45

Suicide

US

UK

Japan

Korea

Australia

Mexico

RussFed

CzechRep

France

Sweden

Israel

Trends in Suicide, Selected Countries, 1990-2011

% Change per Capita in Adult Alcohol Consumption, Selected Countries, 1990-2011

-7

2

-21

-2-6

4

62

2

-21

16

-29

33

-40

-20

0

20

40

60

80

Alcohol

US

UK

Japan

Korea

Australia

Mexico

RussFed

CzechRep

France

Sweden

SoAfrica

Israel

% Change in Smoking Rates, Selected Countries, 2000-2011

-23

-27 -26

-11

-24

-3

5

-14

-31

-43

-23

-50

-40

-30

-20

-10

0

10

US

UK

Japan

Korea

Australia

RussFed

CzechRep

France

Sweden

SoAfrica

Israel

Prevalence of Obesity Among Adults in Selected Countries, 2011

0

5

10

15

20

25

30

35

40

Women Men

Future Health Issues

■ Air Pollution

■ Global Warming

■ Increasing Population Diversity and Refugees!

Air Pollution■ Particulate Matter2.5 and Ozone Production

Source: OECD Environmental Outlook to 2050: The Consequences of Inaction, http://dx.doi.org/10.1787/9789264122246-en

“Worst” areas for Ozone(% days 8-hr max>100 μg/m3) and PM2.5 (Annual mean)

City Ozone City PM 2.5

Rome 32.3 Bucharest 38.2Athens 32.2 Budapest 33.7Marseille 28.0 Ljubljana 29.4Ljubljana 23.9 Athens 29.4Toulouse 22.9 Valencia 23.0

Pascal, Corso, Chanel et al., 2013

“Worst” areas for Ozone(% days 8-hr max>100 μg/m3) and PM2.5 (Annual mean)

City Ozone City PM 2.5

Rome 32.3 Bucharest 38.2Athens 32.2 Budapest 33.7Marseille 28.0 Ljubljana 29.4Ljubljana 23.9 Athens 29.4Toulouse 22.9 Valencia 23.0

Pascal, Corso, Chanel et al., 2013

“Best” areas for Ozone(% days 8-hr max>100 μg/m3) and PM2.5 (Annual mean)

City Ozone City PM 2.5

Dublin 0.7 Stockholm 9.4Seville 1.0 Dublin 10.5Bilbao 2.2 Malaga 12.8Valencia 2.6 London 13.1London 3.2 Toulouse 14.2

Pascal, Corso, Chanel et al., 2013

“Best” areas for Ozone(% days 8-hr max>100 μg/m3) and PM2.5 (Annual mean)

City Ozone City PM 2.5

Dublin 0.7 Stockholm 9.4Seville 1.0 Dublin 10.5Bilbao 2.2 Malaga 12.8Valencia 2.6 London 13.1London 3.2 Toulouse 14.2

Pascal, Corso, Chanel et al., 2013

So you think there’s little we can do about Air Pollution?

Climate Change – Global Warming

■ Greenhouse Gases– O3

– CO2,

– Methane – CFCs (less so, these days)

■ Several threats to Public Health– Natural Disasters – Floods, Wildfires, Extreme Storms– Heat Waves and Sea-level Rise

Natural Disasters■ Storms, floods, cyclones, landslides, wildfires, droughts

– 1970 to 2012 8,335 disasters ■ 1.94 million deaths■ $2.4US Trillion in economic losses

– Consequences■ Large-scale dislocation of populations■ Often to places ill-prepared to cope■ Displaced pops often subject to:

– Undernutrition, violence, sexual abuse, mental illness including PTSD

– Crude mortality rate as much as 30x base rate, often highest in children <5 years

Patz, Grabow, & Limaye, 2014; Haines et al., 2006

Heat Waves■ Mortality relationship is J-shaped with high mortality at

highest temperatures

■ European 2003 heat wave– Killed 40,000 in 2 weeks

Patz, Grabow, & Limaye, 2014; Ballester, Robine, Herrmann, & Rodo, 2011;

Place Excess Mortality

England and Wales 2,091

Italy 3,134

France 14,802

Portugal 1,854

Spain 4,151

Switzerland 975

Netherlands 2,200

Germany 1,410

TOTAL: 30,617

Haines et al., 2006

Heat Waves

■ Clearly a Public Health Issue– How prepared are we?– Death toll in 2003 implies not too well!

■ Need emphasis on public education■ Subsidies for elderly re: HVAC systems?■ “Safe” zones in cities – Urban Heat Islands!

Sea-level rise■ 14 of the world’s 19 Mega-cities are situated at sea-level

Patz, Grabow, & Limaye, 2014

Sea-level rise

■ Global sea levels rose 17 cm during 20th Century (>1/2 foot)

■ Pace of rise will accelerate during 21st Century– Midrange estimates – 26- to 98-cm rise by 2080 (> 3

feet)– Loss of up to 22% of world’s coastal wetlands– 200 million people at risk for:

■ Displacement■ Salt water intrusion into freshwater aquifers■ Disruption of storm water drainage and sewage disposal

systems, YET

The Catastrophe That Must Not Be Named368

By now you may have heard that Florida Gov. Rick Scott is a flat-out global warming denier, even though his state is arguably the most vulnerable to sea level rise and other problems that are surely to come if we do nothing.

•But even doing nothing is too much for Scott. Four former officials at Florida’s Department of Environmental Protection have claimedthat Scott put out an unwritten rule ordering that no one at the DEP even use the phrases global warming or climate change in any of their communications.

“King Tide” in Miami, Florida

Climate Change – Indirect Consequences to Human Health

■ Floods – rapid rise floods – mostly drowning plus:

■ Infectious Diseases– Water- and Food-borne– Vector-borne– Mosquito-borne– Tick-borne

■ Diarrheal diseases –– Coastal flooding in low lying areas– Inland flooding in “former socialist economies” (Haines et al., 2006)

■ Already causing 150,000 death/year

Issues of Diversity

■ REVES– Most presentations on diversity have been in 3 areas:

■ SES differences – largely education and occupation■ Regional differences – largely UK and US■ Ethnic differences – largely from the US

■ BUT– There is increasing diversity within the EU– Implications for Differential Health Status and Social

Cohesion

Foreign-born as % of Total Population, 2000 and 2013

Trends in Migration

Asylum Seekers, Average Annual % Change, 2010 - 2014

32,0

12,9

52,8

19,1

38,4

1,9

114,9

3,7

17,2

32,6

-5,8 -4,3

15,625,0

4,5

65,3

-20,0

0,0

20,0

40,0

60,0

80,0

100,0

120,0

140,0

Germany US Turkey Sweden Italy France Hungary UK

Austria Denmark Belgium Poland Spain Japan CzechRep Bulgaria

Source: UNHCR and OECD International Migration Database

And what about their health?

■ EU countries have universal health coverage

■ Does not mean health care is accessed equally

■ Migrants, in particular– Coming from places where ‘authorities’ represent threat– Language, cultural barriers– Underlying health – probably not as good – particularly

maternal and neonatal

And Social Cohesion?■ Threat Hypothesis

– More diverse societies often lead to lower generalized trust and loss of sense of community■ Not just among ethnic minorities■ Also among the dominant groups

■ Diversity causes feelings of threat– And increased negative “out-group” orientations

■ US and Canadian studies– Racially diverse cities, communities, neighborhoods– Generalized trust tends to be lower for ‘visible’ minorities and white majorities

■ Evidence in US???– Mysterious success of Donald Trump– Amplified by level of economic inequality

Source: Hooghe, Reeskens, Stolle, & Trappers, 2006; Strauss, Connerley, & Ammermann, 2003

Impact of Migration on This!

■ Why do we pay attention to Donald Trump talking about patrolling Muslim areas in the US

1. He’s an idiot2. He’s playing on fear – A Republican hallmark in trade

(GWB in 2004)

■ Are citizens of Belgium and France immune to this?

■ If Threat Hypothesis is correct, rapid rises of migrants –particularly ‘visible’ minorities – further erode social cohesion

Future Directions for REVES■ Air Pollution & Global Warming (Climate Change)

– Probably not specifically on our agenda –– Sure hope it is in APHA, PAA

■ More collaboration across countries –– Increasing research being done within EU –– The more the better

■ More emphasis on Issues of Health in Subpopulations –– Definitions?– Adequate attention paid in large scale surveys?– Statistical power – problematic with iMaCh, other

programs

Thank you and Enjoy the Rest of REVES!!

Per Capita Health Expenditures, as % of GDP

9,3 9,311,6 11,2 10,8

6,6

17,9

0

5

10

15

20UK France Denmark Greece Lithuania Russia US

Source: European Health for All Database

Selected Other Countries:

4,7 4,95,5 5,6 5,6

6,4 6,47,1 7,2 7,4

8,8

10,2

11,7

0,0

2,0

4,0

6,0

8,0

10,0

12,0

14,0

2014

By Region

-6,0

-4,0

-2,0

0,0

2,0

4,0

6,0

8,0

10,0

12,0

14,0

2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015 2016 2017 2018

GDP Growth by Region - 2001 to 2014, Projected 2015-2018

East Asia & Pacific Latin America & Caribbean Europe & Central Asia

Middle East & N. Africa Sub-Saharan Africa United States

“Recent” GDP Growth – High Income and Developing Countries

-6,0

-4,0

-2,0

0,0

2,0

4,0

6,0

8,0

10,0

2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015 2016 2017 2018

2001 to 2014, 2015-2018 Projected

High Income Countries Developing Countries

Mid-2000’s Gini Coefficients

CO2 Emissions attributable to population size and age structure: Germany, 1950 to 2100

Source: Kluge, Zagheni, Loichinger, & Vogt, 2014

Trends in REVES Topics -

0,00

5,00

10,00

15,00

20,00

25,00

30,00

35,00

1990 1991 1992 1994 1995 1996 1997 1998 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014

Definitional Issues – NOT including Harmonization

Methods

0,00

5,00

10,00

15,00

20,00

25,00

30,00

35,00

Healthy Life Expectancy –Single and Multiple Country

0,00

5,00

10,00

15,00

20,00

25,00

30,00

35,00

1990 1991 1992 1994 1995 1996 1997 1998 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014

Single Multiple Linear (Single) Linear (Multiple)

Trends in Health/Disabilityand Mortality

0,00

5,00

10,00

15,00

20,00

25,00

30,00

35,00

1990 1991 1992 1994 1995 1996 1997 1998 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014

Trends Mortality Linear (Trends) Linear (Mortality)

SES/Diversity Issues – US and Elsewhere

0,00

5,00

10,00

15,00

20,00

25,00

30,00

35,00

1990 1991 1992 1994 1995 1996 1997 1998 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014

US Other Linear (US) Linear (Other)

Death Rates from Transport Accidents, Selected Countries, 2011

12,4

3,64,5

13,8

6,8

17,5

19,2

8,27,1

3,2

14,1

5,9

0

5

10

15

20

25

Death Rates

US

UK

Japan

Korea

Australia

Mexico

RussFed

CzechRep

France

Sweden

So Africa

Israel

Death Rates– Alcohol-Related

Source: European Health for All Database

60,4

137,5

80,7

156,9

142,5

63,657,1 61,5

34,4

144,7

74,4

48,8

0,0

20,0

40,0

60,0

80,0

100,0

120,0

140,0

160,0

180,0

Denmark France Greece Lithuania Poland UK

1990 2011-2013

Death Rates– Smoking-Related

Source: European Health for All Database

191,5 186,9

278,0

478,2

279,3

408,6

173,5

106,7

181,3

454,9

205,0180,3

0,0

100,0

200,0

300,0

400,0

500,0

600,0

Denmark France Greece Lithuania Poland UK

1990 2011-2013

Global Premature Deaths (in Millions of People) from Selected Environmental Risks, 2010-2050

0

0,5

1

1,5

2

2,5

3

3,5

4

Ground Level Ozone Particulate Matter

2010 2030 2050

Source: OECD Environmental Outlook to 2050: The Consequences of Inaction, http://dx.doi.org/10.1787/9789264122246-en

Using Beijing @ Case Study

■ High population growth, traffic density and levels of particulate matter

■ Biggest culprits:– Residential wood burning– Coal burning– “Mineral aerosols from resuspended road dust”– Solid waste management

■ Result –– Impact on Mort/Morb –

■ Varies by season■ PM2.5 and Potassium had highest impact on non-accidental

mortality– Similar to results found in the Netherlands, Phoenix, Santa

Clara County

Li, Xin, Wang et al., 2015

European Studies

■ Long term exposure to PM2.5 linked to natural cause mortality (Beelen et al., 2014)

– Little difference between 22 cohorts examined– Mortality from Lung Cancer and Stroke, not IHD or

Respiratory Diseases– Association between LT Exp to PM2.5 and Mortality found

even in areas already below EU standards for PM

Excess Mortality during 2003 European Heat WavePlace Excess Mortality

England and Wales 2,091

Italy 3,134

France 14,802

Portugal 1,854

Spain 4,151

Switzerland 975

Netherlands 2,200

Germany 1,410

TOTAL: 30,617

Haines et al., 2006

Big question -■ How well will humans adapt to increasingly hot environment?

– Public health education– Health warning systems– Emergency preparedness– Add Boil water notices– Risk assessment for extreme rainfall events– Risk assessment for health effect of algal blooms– ZIKA!!!– High Pollution day warnings – Food hygiene measures and enforcement

Percent Change in Foreign-Born Residents: 2002-2013 (2012 – France)

18,4

39,6

11,7

47,937,1

-42,6

11,20,1

60,7

9,4

87,8

24,1

46,4

13,9 18,5

-60

-40

-20

0

20

40

60

80

100

Austria Belgium Canada CzechRep Denmark

Estonia France Germany Hungary Netherlands

Norway Switzerland UK US Australia

Source: UNHCR and OECD International Migration Database