Post on 16-Oct-2021
transcript
Proceedings of the ASME
First Global Congress on
NanoEngineering for Medicine and Biology
-2010-
NANOENGINEERING FOR MEDICAL DIAGNOSTICS
NANOENGINEERING FOR MEDICAL THERAPEUTICS AND IMAGING
NANO-/MICRO-FLUIDICS FOR MEDICAL
DIAGNOSTICS AND THERAPEUTICS
NANOENGINEERING FOR REGENERATIVE MEDICINE
MANUFACTURING AND MATERIALS FOR NANOMEDICINE
MULTISCALE MODELING IN BIOLOGICAL SYSTEMS
BIOLOGICAL NANOMECHANICS
presented at
THE ASME 2010 FIRST GLOBAL CONGRESS ON
NANOENGINEERING FOR MEDICINE AND BIOLOGY
FEBRUARY 7-10, 2010
HOUSTON, TEXAS, USA
sponsored by
ASME NANOTECHNOLOGY INSTITUTE
ASME
Three Park Avenue New York, N.Y. 10016
CONTENTS
NANOENGINEERING FOR MEDICAL DIAGNOSTICS
NEMB2010-13014 1
Nanotechnology Based Point-of-Care Diagnostics and Therapeutics for NeurologicalDisorders
Vijay K. Varadan
NEMB2010-13017 3
Cellulose Electro-Active Paper for Biomedical ApplicationsJaehwan Kim and Yi Chen
NEMB2010-13029 5
Sensory Biofuel Cell for Self-Sustained Glucose Sensing in Healthcare Applications for
Diabetes Patients
Pratyush Rai, Jining Xie, Vijay K. Varadan, Thang Ho, and Jamie A, Hestekins
NEMB2010-13055 7
Development of Neural Probe With Wireless Power Feed
Sang H. Choi, Kyo D. Song, Yeonjoon Park, and Uhn Lee
NEMB2010-13065 11
Tuberculosis Diagnostics Using a Nanotip Sensor
Woon-Hong Yeo, Jae-Hyun Chung, and Kyong-Hoon Lee
NEMB2010-13069 13
Characterization of Biosensor Detection Process at Ultra-Low Concentration Through a
Stochastic Particle Model
Samar Shah, Yaling Liu, and Walter Hu
NEMB2010-13079 15
A Study of Bifurcation Design Used in CD-ELISA Micro-Fluidic Platform
Samuel I. En Lin
NEMB2010-13083 17
Modeling of Spin Coating Process to Control Submicron Film Thickness of Permeation LayerKama! Sarkar
NEMB2010-13124 19
Poly-Silicon Nanowire FET Chemical Sensor
Chih-Ting Lin, Che-wei Huang, and Jui-ching Wang
IMEMB2010-13126 21
Gold Nanoparticle Self Assembly on Diblock Copolymers for Application as
Biomolecular Sensors
Sarah M. Adams and Regina Ragan
NEMB2010-13128 23
Templated Assembly by Selective Removal for Size-Selective Sorting of Biological Materials
Gunjan Agarwal and Carol Livermore
ix
NEMB2010-13142 25
Self Thermal Elimination of Nanomechanics-Based Biosensor Using a Single Free-StandingPiezoresistive Microcantilever
Yu Fu Ku, Yi-Kuang Yen, Ping-Yen Lin, and Long-Sun Huang
NEMB2010-13143 27
Ultra Sensitive Detection of Eneterovirus 71 by Modified Electrochemical Impedance
SpectroscopyShin-Hua Tseng, Dion T. Tseng, Tzu-Cheng Lee, Tsai-Mu Cheng, Jyh-Yuan Yang,
Ruo-Yu Hsieh, Chuan-Mei Tsai, and Chia-Ching Chang
NEMB2010-13148 29
Electron Transportation Behavior in Single Crystal Silicon Nanowires
Yu C. Shih, Chuin S. Chen, Chih T. Lin, and Kuang C. Wu
NEMB2010-13185 31
Fabrication of Polymeric Nano-Valve Array for Biomedical ApplicationsKuang-Fu Chang, Wen-Pin Shih, and Chuin-Shan Chen
NEMB2010-13195 35
Aptamer-Based Lab-On-Chip for Cancer Cell Isolation and Detection
Yuan Wan, Young-tae Kim, Li Na, Andrew D. Ellington, and Samir M. Iqbal
NEMB2010-13207 37
Magnetic Iron Oxide Nanotubes and Their Neuronal Applications
Jining Xie, Linfeng Chen, Vijay K. Varadan, and Malathi Srivastan
MEMB2010-13212 39
Wireless Point-of-Care Patient Monitoring System Using Zigbee and Wi-Fi Standards
Sechang Oh, Hyeokjun Kwon, Hargsoon Yoon, and Vijay K. Varadan
NEMB2010-13214 41
Alkanethiol Self-Assembled Monolayers on Microcantilever Biosensor
Chia-Ching Chou, Shu-Wei Chang, and Chuin-Shan Chen
NEMB2010-13227 43
Using Actuated Cilia to Regulate Motion of Microscopic Particles
Alexander Alexeev, Rajat Ghosh, Gavin A. Buxton, 0. Berk Usta, and Anna C. Balazs
NEMB2010-13237 45
Studying the Mechanical Sensitivity of Human Colon Cancer Cells Through a Novel
Bio-MEMS Force Sensor
Xin Tang, Tony Cappa, Theresa B. Kuhlenschmidt, Mark S. Kuhlenschmidt, and
TaherA. Saif
NEMB2010-13238 47
Nonlinear Parametric Resonance for NEMS and MEMS Biosensor ApplicationsDumitru I. Caruntu and Martin W. Knecht
NEMB2010-13256 49
Electrical Impedance Spectroscopy Microsystem as a Tool for Cancer Cell Analysis
Hyun Soo Kim, Younghak Cho, A. Bruno Frazier, Zhuo G. Chen, Dong Moon Shin, and
Arum Han
x
NEMB2010-13268 51
Modeling and Simulations of the Motion of Bio-Inspired Micro Swimming Robots
A. F. Tabak and S.Yesilyurt
NEMB2010-13272 53
Dynamic Manipulation and Precision Localization of Nanoparticles Internal to Cells
Peter Tseng, Jack W. Judy, and Dino Di Carlo
IMEMB2010-13278 55
Platelet Nano-Forces are Similar on Fibronectin and Fibrinogen LigandsXin M. Liang and Nathan J. Sniadecki
MEMB2010-13295 57
"0NC0SENS0R" for Noninvasive High-Specificity Breast Cancer Diagnosis byCarbogen-Enhanced Neutron Femto-Oxymetry
Bogdan C. Maglich and Orhan Nalcioglu
IMEMB2010-13299 59
Design and Optimization of a Nanotip Sensor via Immersed Molecular Electrokinetic
Finite Element Method
Adrian M. Kopacz, Wing K. Liu, and Jae-Hyun Chung
NEMB2010-13302 61
Switching Between Magnetic or Oxigen Sensory Input for the MC-1 Flagellated Bacteria
to be Used for Controlling the Motion of Swarms of Bacterial Microscale Nanorobots
Sylvain Martel, Mahmood Mohammadi, and Nisryn Mokrani
NEMB2010-13307 63
Shadow Edge Lithography and Application to Nanofluidics
Woon-Hong Yeo, Dong Won Lee, Kyong-Hoon Lee, and Jae-Hyun Chung
NEMB2010-13313 65
Nanofabricated Sensing Electrodes in a Batteryless Endoluminal Sensing Telemeter for
Diagnosis of Gastroesophageal Reflux Disease (GERD)Lun-Chen Hsu, Wen-Ding Huang, Shou-Jiang Tang, Stuart Spechler, H. F. Tibbals, and
J.-C. Chiao
NEMB2010-13366 67
Added-Mass Effect in Modeling of Cilia-Based Devices for Microfiuidic SystemsJ. Kongthon, B. McKay, D. lamratanakul, Kieseok Oh, Jae-Hyun Chung, James Riley, and
Santosh Devasia
NEMB2010-13367 71
Manipulation of Clinical Materials Using AC Electrokinetics
Mandy L. Y. Sin and Pak Kin Wong
NEMB2010-13379 75
An Electrochemical Dopamine Sensor Based on a Flexible Conductive Film of Single-WallCarbon Nanotubes (SWCNT) on PET
Naser Hamdi, Vanessa Tolosa, Harold Monbouquette, Abdelaziz Rahy, and
DuckJoon Yang
xi
IMEMB2010-13383 77
A New Platform for Profiling Active Proteases With Single-Molecule Sensitivity
M. Yusra Satoglu-Dogan, Andrey Revyakin, Sang Park, Alexandros Pertsinidis,
Christopher Brown, Steven Chu, Charles S. Craik, and Arun Majumdar
NANOENG1NEERING FOR MEDICAL THERAPEUTICS AND IMAGING
NEMB2010-13006 79
Nanocidals for Osteomyelitis ManagementYousef Haik and Shahnaz Qadri
NEMB2010 13018 83
Non-Cd Based Quantum Dots for Molecular ImagingJinhao Gao, Kai Chen, Renguo Xie, Xiaogang Peng, and Xiaoyuan Chen
NEMB2010-13022 85
Magnetic Targeting of TherapeuticsKenneth Dormer, Sunny Po, Kejian Chen, Benjamin Scherlag, Isaac Rutel, Kytai Nguyen,
Satish Kyriyavar, Brian Grady, Benjamin Shapiro, Xinsheng Gao, Xiaoping Du,
David Bourne, Kar-Ming Fung, and Richard Kopke
INJEMB2010-13050 87
Gold Nanoshell Mediated Heating of Brain Tumors
Anil M. Shetty, Jon A. Schwartz, Joshua Yung, Roger J. McNichols, Roger Price,
John D. Hazle, and R. Jason Stafford
NEMB2010-13059 89
Development of Peroxidase Biosensor for Detection of Endocrine DisruptingChemicals (EDCs)
Camille Gonzalez, Anais Vazquez, Angel Morales, Liz Diaz, Kai Griebenow, and
Carlos R. Cabrera
NEMB2010-13115 93
Enhanced Generation of Reactive Oxygen Species Using Gold Nanoparticles ConjugatedWith Protoporphyrin IX
Maung Kyaw Khaing Oo, Maria Gomez, Hongjun Wang, and Henry Du
NEMB2010-13149 95
Magnetic Resonance Imaging of Magnetic Particles for Targeted Drug DeliveryChristian Dahmen, Tim Wortmann, and Sergej Fatikow
NEMB2010-13172 97
Hyperthermic Cytotoxicity Induced by Noninvasive Radiofrequency Field Exposure After
Delivery of EGFR Family Targeted Gold NanoparticlesEvan S. Glazer, Warna D. Kaluarachchi, and Steven A. Curley
NEMB2010-13225 99
Highly Paramagnetic Tumor-Targeted Contrast AgentsAndrew Tsourkas
NEMB2010-13263 101
Chemotherapeutic Synergy Enhancement Through Micellar NanotherapeuticsElvin Blanco, Takafumi Sangai, Funda Meric-Bernstam, and Mauro Ferrari
xii
NEMB2010-13303 105
Intracellular Trafficking of Nano-Carriers
Silvia Ferrati, Rita E. Serda, Andrew Bean, and Mauro Ferrari
NEMB2010-13314 109
Multimodality and Advanced Biomedical Imaging for Clinical and Research ApplicationsLuc Bidaut
NEMB2010-13377 111
Elucidating the Interactions of Nanomaterials With Biological SystemsWarren C. W. Chan
NANO-/MICRO-FLUIDICS FOR MEDICAL DIAGNOSTICS AND
THERAPEUTICS
NEMB2010-13007 113
Hydrodynamically Confined Microflows for Cell Adhesion Strength Measurement
Kevin V. Christ and Kevin T. Turner
NEMB2010-13030 115
Micropattem Effect on Breast Cancer Cells Behavior on Isotropically Etched Silicon
Microenvironments
Mehdi Nikkhah, Jeannine S. Strobl, Bhanu Peddi, Adedamola Omotosho, and
MasoudAgah
NEMB2010-13132 117
Development of Microfluidic Chips to Study the Effects of Shear Stress on Cell Functions
Jianbin Wang, Jinseok Heo, and Susan Z. Hua
NEMB2010-13135 119
A Microfluidic Chip for Studying Intercellular Communication via Gap Junction Channels
Cedric Bathany, Thomas Suchyna, and Susan Z Hua
NEMB2010-13183 121
Molecular Delivery Into Live Cells Using Gold Nanoparticle Arrays Fabricated by PolymerMold Guided Near-Field Photothermal Annealing
Ting-Hsiang Wu, Fan Xiao, Sheraz Kalim, Tara Tesiaa, Michael A. Teitell, and
Pei-Yu Chiou
NEMB2010-13196 123
Nanofluidic Devices for Rapid Analysis of DNA and Proteins
Jianping Fu
NEMB2010-13210 125
Enhanced Tumor Cell Separation by Surfaces Functionalized With Combinations of
Bioadhesive Proteins
Ja Hye Myung, Can A. Launiere, Khyati A. Gajjar, David T. Eddington, and
Seungpyo Hong
NEMB2010-13234 127
Fluorescence Amplification Using Biospecific Nanoparticle Conjugates as Labels in
Microfluidic Heterogeneous ImmunoassaysPeng Li, Hong Chen, Constantine Anagnostopoulos, and Mohammad Faghri
xiii
NEMB2010-13235 129
Integrated Diagnostics for Rapid Quantitation of Biomarkers in Human Fluids
Chenlu Hou, Kelly Karns, and Amy E. Herr
NEMB2010-13236 131
Electrokinetic Transport of Molecules Through Nanochanneled Membranes
Alessandro Grattoni, Xuewu Liu, Zongxing Wang, Jaskaran Gill, Arturas Ziemys, and
Mauro Ferrari
IMEMB2010-13281 135
Nanochannels Fabrication: Filling and DNA ManipulationV. R. S. S. Mokkapati, V. Di Virgilio, J. Mollinger, J. Bastemeijer, and A. Bossche
NEMB2010-13297 139
Characterzation and Quality Control for Micro- and Nanochanneled Silicon Membranes
Jaskaran Singh Gill, Alessandro Grattoni, Arturas Ziemys, and Mauro Ferrari
NEMB2010-13300 143
A Microfluidic Assay for Metastasis Potential AnalysisSmitha M. N. Rao, Uday Tata, Victor K. Lin, Jer-Tsong Hsieh, Kytai Nguyen, and
J.-C. Chiao
NEMB2010-13317 145
Development of a Microfluidic Injection and Perfusion Device for Single Cell Study
Hsiu-hung Simor Chen, Zhiquan Shu, Lei Cheng, and Dayong Gao
NEMB2010-13328 149
A Self-Contained Microfluidic Cassette for the Detection of Nucleic Acids at the
Point-of-Care
Dafeng Chen, Xianbo Qiu, Michael Mauk, and Haim H. Bau
MEMB2010-13341 151
Microtechnologies for Neurobiology
Henry C. Zeringue
NEMB2010-13346 155
Bi-Directional AC Electroosmosis Micropump for Medical ApplicationsNazmul Islam
NEMB2010-13348 157
Analysis of Red Blood Cell Deformation in a Microfluidic Device
Giovanna Tomaiuolo, Stefano Guido, and Antonio Cassinese
IMEMB2010-13381 159
Nanomedical Applications of OptofluidicsDavid Erickson
NAIMOENGINEERING FOR REGENERATIVE MEDICINE
NEMB2010-13037 161
Effects of an Experimental Drug, Suberoylanilide Hydroxamic Acid (SAHA), on Attachment,
Spreading, and Stiffness of Human Breast Cancer Cells on Silicon Substrates
Jeannine S. Strobl, Mehdi Nikkhah, Robert Rhoades, and MasoudAgah
xiv
NEMB2010-13114 163
Innovative Magnetic Nanoparticles Approaches for Bone and Osteochondral
Tissue EngineeringA. Russo, S. Panseri, D. Casino, T. Shelyakova, A. Tampieri, N. Bock, V. Goranov,
E. Landi, C. Dionigi, A. Riminucci, V. Dediu, and M. Marcacci
NEMB2010-13199 165
Mechanical Regulation of Stem Cell Differentiation on Geometrically ModulatedElastomeric Substrates
Jianping Fu
NEMB2010-13282 167
Coaxial Electrospinning Biopolymer With Living Cells
Qudus Hamid and Wei Sun
NEMB2010-13287 173
Nanomechanics of Electrospun Fibers for Tissue EngineeringStephen Baker, Justin Sigley, Christine Carlisle, Joel Stitzel, Joel Berry, Keith Bonin, and
Martin Guthold
NEMB2010-13290 175
The Effect of Nano Hydroxyapatite Particles on Morphology and Mechanical Properties of
Microcellular Injection Molded Polylactide/Hydroxyapatite Tissue Scaffold
Adam Kramschuster, Lih-Sheng Turng, Wan-Ju Li, Yiyan Peng, and Jun Peng
NEMB2010-13337 179
Novel Biomimetic Scaffold for Tendon/Ligament Tissue EngineeringTyler J. Allee and Wan-Ju Li
NEMB2010-13344 181
A Micro-Architectural Based Structural Model for Elastomeric Electrospun ScaffoldsAntonio D'Amore, John A. Stella, David E. Schmidt, William R. Wagner, and
Michael S. Sacks
NEMB2010-13371 183
Engineering Dense Connective Tissues via Anisotropic Nanofibrous Scaffolds With HighSacrificial Fiber Content
Brendon M. Baker, Amy M. Silverstein, and Robert L. Mauck
IMEMB2010-13372 185
Development of Nanofiber Scaffolds for Engineering an Artificial Salivary GlandMelinda Larsen, Riffard Jean-Gilles, David Soscia, Sharon Sequeira, Michael Melfi,
Anand Gadre, and James Castracane
MANUFACTURING AND MATERIALS FOR NANOMEDICINE
NEMB2010-13021 187
Protein Molecules as Natural Nano Bio Devices: Mobility AnalysisZahra Shahbazi, Horea T. Hies, and Kazem Kazerounian
xv
NEMB2010-13025 189
Characterization of a Magnetic Microactuator for Manipulating Nanoparticles in
Gene Delivery ApplicationsEva Flick, Wenzhong Li, Jonas Norpoth, Christian Jooss, Gustav Steinhoff, and
Hans H. Gatzen
NEMB2010-13048 191
Material Study for Electrowetting-Based Multi-Microfluidics Array Printing of HighResolution Tissue Construct With Embedded Cells and Growth Factors
Chris G. Geisler, David M. Wootton, Peter I. Lelkes, Richard Fair, and Jack G. Zhou
NEMB2010-13078 195
Ink-Jet as a Manufacturing Method for Drug Delivery, Tissue Engineering, and Medical
Device ApplicationsBogdan V. Antohe and David B. Wallace
NEMB2010-13088 197
Ethical Challenges Posed by NanotechnologySubrata Saha and Stephen J. Florczyk
NEMB2010-13119 199
Preparation of Interconnected Microporous Poly(glycolic-co-lactic acid) With HighHydroxyapatite Loading
Wei Zhang, Donggang Yao, Qingwei Zhang, Jack G. Zhou, and Peter I. Lelkes
NEMB2010-13122 203
Controllable Growth of Gradient Structures for Biomedical ApplicationsWei Zhang, Donggang Yao, and Jack G. Zhou
NEMB2010-13131 207
Electrospun Recombinant Protein Polymer IManofibers as a Biomaterial
Weiguo Qiu, Yiding Huang, Joseph Cappello, and Xiaoyi Wu
NEMB2010-13141 209
Mechanical and In-Vitro Cell Compatibility Properties of Silk-Elastinlike Protein-Based
Biomaterial
Weibing Teng, Yiding Huang, Joseph Cappello, and Xiaoyi Wu
NEMB2010-13152 211
A Hybrid Nano-Bioprinting Device for Tissue EngineeringKivilcim Buyukhatipoglu, Wei Sun, and Alisa Morss Clyne
NEMB2010-13164 213
Electrostatic Self-Assembly of Functionalized Nanodiamonds and Their Binding CapacityWith Doxorubicin Drugs
Ashfaq Adnan and Wing Kam Liu
NEMB2010-13166 217
Micro-Porous PLLA Scaffolds for Orthopedic Surgical Fixation Devices
Qingwei Zhang, Wei Zhang, Donggang Yao, David M. Wotton, Peter I. Lelkes, and
Jack G. Zhou
xvi
NEMB2010-13179 219
Photothermal Therapy of Glioma in a Mouse Model With Near-Infrared Excited Nanoshells
Emily S. Day, Linna Zhang, Nastassja A. Lewinski, Patrick A. Thompson,Rebekah A. Drezek, Susan M. Blaney, and Jennifer L. West
NEMB2010-13180 221
Cancer Imaging and Thermal Therapy Facilitated by Nanoparticles and MultiphotonMicroscopy
Emily S. Day, Lissett R. Bickford, Rebekah A. Drezek, and Jennifer L. West
NEMB2010-13181 223
Gas-Phase Production of Multifunctional Composite Nanoparticles by Photoinduced
Chemical Vapor DepositionAdam Boies, Pingyan Lei, Jeff Roberts, and Steven Girshick
NEMB2010-13209 225
Simulation of the Diffusion of Doxorubicin (DOX) in Polymer Pores for a Multiscale
Nanodiamond Based Drug Delivery SystemPaul D. Arendt, Wei Chen, and Wing Kam Liu
NEMB2010-13242 227
Unnatural Amino Acids Modified Clays for Design of Scaffolds for Bone Tissue EngineeringKalpana S. Katti, Dinesh R. Katti, and Avinash H. Ambre
NEMB2010-13258 229
Factors Affecting the Assembly of Carbon Nanostructures With Cells and EnzymesSonal Mazumder, Suvojit Ghosh, Joseph O. Falkinham, III, and Ishwar K. Puri
IMEMB2010-13266 233
Structure and Surface Properties of Nanodiamonds: A First-Principles Multiscale ApproachAditi Datta, Yao Fu, Mesut Kirca, and Albert To
IMEMB2010-13273 237
Multiscale Modeling and Simulation for Nanodiamond-Based Therapeutic DeliveryWing Kam Liu and Ashfaq Adnan
NEMB2010-13326 239
Fabrication of Single-Crystal Nanospherical Hydroxyapatite Powder for Biomedical
Applications
Peyman Honarmandi
NEMB2010-13336 241
PLLA-Nanodiamond Composites and Their Application in Bone Tissue EngineeringQingwei Zhang, loannis Neitzel, Vadym N. Mochalin, Isabel Knoke, David M. Wotton,
Yury Gogotsi, Peter I. Lelkes, and Jack G. Zhou
IMEMB2010-13339 243
Functional Nanodiamond Internalization Mechanisms and Kinetics
Robert Lam, Xueqing Zhang, Mark Chen, and Dean Ho
NEMB2010-13340 245
A Platform Approach to Gene Delivery Via Surface Modified Nanodiamonds
Xue-Qing Zhang, Mark Chen, Robert Lam, Xiaoyang Xu, Eiji Osawa, and Dean Ho
xvii
IMEMB2010-13354 247
Metals, Semiconductors, and Alloy Nanowires on DNA Scaffolds: Synthesis and Device
ApplicationsSubrata Kundu and Hong Liang
NEMB2010-13357 249
Ordered Au Nanodisk and Nanohole Arrays: Fabrications and ApplicationsYue Bing Zheng, Jinjie Shi, Bala Krishna Juluri, and Tony Jun Huang
MULTISCALE MODELING IN BIOLOGICAL SYSTEMS
NEMB2010-13012 253
Multiscale Modeling of Blood Flow in Cerebral Malaria
Dmitry A. Fedosov, Bruce Caswell, and George Em Karniadakis
NEMB2010-13013 255
E-cadherin N-glycosylation Modulates the Strength of Adherens Junctions
Sarah J. Shareef, Mihai Nita-Lazar, and Maria A. Kukuruzinska
IMEMB2010-13034 257
Pumping Characteristics of the Lymphatic SystemJames E. Moore, Jr.
NEMB2010-13058 259
On Structure and Elastic Fields of Random Fiber Networks
Hamed Hatami-Marbini and Catalin R. Picu
NEMB2010-13066 261
Multiscale Modeling of Cortical Bone
Elham Hamed, Yikhan Lee, and Iwona M. Jasiuk
NEMB2010-13070 263
Modeling of Drug and Drug-Encapsulated Nanoparticle Transport in Patient-SpecificCoronary Artery Walls to Treat Vulnerable Plaques
Shaolie Hossain, Syed Hossainy, Yuri Bazilevs, Victor M. Calo, and Thomas J. R. Hughes
NEMB2010-13073 265
Influence of Nanoparticle Design on Binding Efficiency
Yaling Liu, Samar Shah, Walter Hu, and Jinming Gao
NEMB2010-13074 267
Modeling DNA Translocation Kinetics in Nanopores With SelectivityAbhijit Ramachandran, Qingjiang Guo, Samir Iqbal, and Yaling Liu
NEMB2010-13090 269
Multiscale Elastic Network Model for Macromolecular Machines
Moon K. Kim, Byeongsoo Lim, and Wing Kam Liu
IMEMB2010-13102 271
Hierarchical Structure Controls IManomechanical Properties of Vimentin Intermediate
Filaments
Markus J. Buehler and Qin Zhao
xviii
NEMB201013106 273
Transition Pathway for the Minus-End Directed Movement of Kinesin-14 NCD
Sirish Kaushik Lakkaraju and Wonmuk Hwang
NEMB2010-13108 275
Structure of Water Hydration Around CollagenKrishnakumar M. Ravikumar and Wonmuk Hwang
NEMB2010-13121 277
Investigation of RBC Remodeling With a Multiscale Model
Qiang Zhu, Zhangli Peng, and Robert J. Asaro
NEMB2010-13123 279
Divide-and-Conquer Based Adaptive Coarse Grained Simulation of RNA
Mohammad Poursina, Kishor Bhalerao, and Kurt Anderson
NEMB2010-13125 283
Fibrin Networks Sustain Large Extensions Due to Unfolding Proteins
Prashant K. Purohit
NEMB2010-13155 285
Swimming Microorganisms in Complex Media
Henry C. Fu, Charles W. Wolgemuth, Vivek Shenoy, and Thomas Powers
NEMB2010-13157 287
Atomistic to Continuum Modeling of DNA Molecules
C. H, Lee, H, Teng, and J. S. Chen
NEMB2010-13160 - 289
Molecular and Mesoscale Mechanisms of Osteogenesis Imperfecta Disease
Sebastien Uzel and Markus J. Buehler
NEMB2010-13165 291
Rho-GTPase Regulation by GEFs, GAPs and GDIs in Cell MigrationXavier Diego, Eugenio Onate, and Wing Kam Liu
NEMB2010-13170 295
Multiscale Modeling of Protein Crystals: Application to Tetragonal LysozymeAmir Reza Zamiri and Suvranu De
NEMB2010-13171 297
Modeling the Effect of Hemodynamics on Cardiac Growth During Embryonic DevelopmentSandra Rugonyi and Kent Thornburg
NEMB2010-13175 299
The Contribution of Proteoglycans to the Mechanical Properties of the Corneal Stroma
Hamed Hatami-Marbini and Peter M. Pinsky
NEMB2010-13216 301
Silica Nanochannel Surface Effect on Monosaccharide TransportArturas Ziemys, Alessandro Grattoni, Jaskaran Gill, and Mauro Ferrari
xix
NEMB2010-13244... 305
Regulating Motion of Magnetic Capsules in Microfluidic SystemsHassan Masoud, Alexander Kilimnik, and Alexander Alexeev
NEMB2010-13253 307
A Hybrid Model for Nanoparticle Targeted Delivery in Blood Flow
Yaling Liu, Jifu Tan, and Samar Shah
NEMB2010-13257 309
Flow Structures in Three-Dimensional Fish-Like Swimming
Xing Zhang, Shizhao Wang, and Guowei He
NEMB2010-13267 311
Numerical Simulation of Arbitrarily Shaped Particle Transport in an Incompressible Flow
M. D. de Tullio, G. Adrian!, P. De Palma, G. Pascazio, and P. Decuzzi
NEMB2010-13269 313
Modeling of Endothelial Cell Adhesion Dynamics Modulated by Molecular Engineering
Adrian M. Kopacz, Brandon J. Tefft, Shu Q. Liu, and Wing K. Liu
NEMB2010-13312 315
Finite Element Framework for Mechanics and Dynamics of Supramolecular Protein
Assemblies
Do-Nyun Kim, Reza Sharifi Sedeh, Cong Tri Nguyen, and Mark Bathe
NEMB2010-13320 317
Mechanical Characterization of Biological Tissue: Finite Element ModelingYue Xuan and Wei Tong
NEMB2010-13347 319
Microstrucutre-Based Modeling of Ti-6AI-4V Lattice Structures and Trabecular Bone
Hang Yao and Wei Tong
NEMB2010-13352 321
Micro-Mechanical Characterisation of Human Cortical Bone
Julien Jonvaux, Elisa Budyn, and Thierry Hoc
BIOLOGICAL NANOMECHANICS
NEMB2010-13010 325
Modeling Nanomechanical Strains in Healthy and Diseased Single-Cells Due to Applied
Fluidic Stresses
Zachary D. Wilson and Sean S. Kohles
NEMB2010-13027 329
Simultaneous Measurements of Diffusion Coefficient on Cell Membrane by Fluorescence
Photobleaching and Single Quantum Dot Tracking TechniquesDonghee Lee, Jeonghoon Lee, Choonho Park, and Jung Kyung Kim
NEMB2010-13032 331
Quantifying the Nanomechanical Properties of Bacillus Anthracis and Implications for
Spore KillingTerri A. Camesano, Paola A. Pinzdn-Arango, and Ramanathan Nagarajan
xx
NEMB2010-13039 333
Nanomechanochemical Delivery of Nanoparticles for Nanomechanics Inside Living Cells
Kyungsuk Yum, Sungsoo Na, Yang Xiang, Ning Wang, and Min-Feng Yu
NEMB2010-13057 335
Inkjet Printing of High-Density Bacterial Arrays for Biosensor Applications
Myoung-Ock Cho, Sunghee Yoon, and Jung Kyung Kim
NEMB2010-13077 337
Nano-Structure of Collagen Fibrils in Human Intervertebral Discs and Its Correlation
With the Tissue Mechanics
Darwesh M. K. Aladin, Kenneth M. C. Cheung, Alfonso H. W. Ngan, Danny Chan,
Victor Y. L. Leung, Chwee Teck Urn, Keith D. K. Luk, and William W. Lu
NEMB2010-13103 339
Hierarchical Structure Controls Nanomechanical Properties of Vimentin Intermediate
Filaments
Markus J. Buehler and Jeremie Bertaud
NEMB2010-13154 341
Growth Responses of Swarming and Gliding Bacteria on Substrates With Different
Levels of Stiffness
Eun-Jung Park, Myoung-Ock Cho, and Jung Kyung Kim
NEMB2010-13156 343
Computational Investigation of Dynamic Properties of Actin Networks With
Crosslinking Proteins
Taeyoon Kim, Wonmuk Hwang, and Roger D. Kamm
NEMB2010-13177 345
Multifaceted Nano- and Micropatterned Surfaces for Cell Adhesion ManipulationJohn H. Slater, Jordan S. Miller, Shann S. Yu, and Jennifer L. West
NEMB2010-13198 347
DNA Damage by NanoparticlesThomas Prevenslik
NEMB2010-13211 349
DNA: Not Merely the Secret of Life
Nadrian C. Seeman
NEMB2010-13233 351
Knockdown of SHP-1 Enhances Endothelial Cell Retention for Vascular RegenerationBrandon J. Tefft, Adrian M. Kopacz, Wing Kam Liu, and Shu Q. Liu
IMEMB2010-13239 353
Mechanically Based Simulations of the Dynamics of Growing Cell Clusters
Ignacio Romero and Juan J. Arribas
NEMB2010-13271 355
Random Sampling Monte-Carlo Approach to Studying Entropic Elasticity Properties of
Cell Proteins and LipidsEduard Karpov
xxi
NEMB2010-13277 357
Molecular Dynamics Study of Nanobio Membranes
Negin Maftouni, M. Amininasab, and Farshad Kowsari
NEMB2010-13311 359
A Theoretical Analysis for the Effect of Substrate Elasticity on Cellular Adhesion
Alireza Sarvestani
NEMB2010-13321 361
Kinetics of Membrane Spreading on Compliant Bio-Adhesive Substrates
Alireza Sarvestani
POSTER SESSION
IMEMB2010-13075 363
Modeling Targeted Drug Delivery in a Vascular Network
Yaling Liu, Kytai Nguyen, Manohara Mariyappa, Samar Shah, and Jifu Tan
NEMB2010-13093 365
Nanoscale Analysis of the Effect of Pathogenic Mutations on Polycystin-1
Liang Ma, Meixiang Xu, and Andres F. Oberhauser
NEMB2010-13298 367
Electrospun Polycaprolactone/Nanodiamond Composite Scaffolds for Bone Tissue
EngineeringAmanee D. Salaam and Derrick Dean
Author Index 371
xxii