Theresa NeSmith Centers for Disease Control and Prevention Center for Global Health Division of Global HIV/AIDS International Laboratory Branch

PEPFAR Priorities

CDC/International Laboratory Branch Key Activities and Partnerships

Capacity Building and Sustainability

• UNAIDS 90-90-90

• Right Thing, Right Place, Right Time (Right Now)

Impact Action Agenda

Focus Resources and Leverage Finances

Efficiency Action Agenda

Increase Transparency, Oversight and Accountability

Sustainability Action Agenda

Ensuring Availability of Services, Systems, Financing and Policies

Partnership Action Agenda

Impact Through Collaborations

Human Rights Action Agenda

Addressing the Human Rights Challenges

Rapid Test Quality Improvement Initiative

Improving the Quality of Point of Care Diagnostics

6

Completing the Quality Assurance Cycle for uptake and coverage

RTQII

1. Policy

2. Tester Certification

3. Proficiency Testing

4. Standardized HIV Register

5. Post Market Surveillance

6. Site Certification

Partnerships for Quality Diagnostics

World Health Organization (WHO)

African Society for Laboratory Medicine (ASLM)

Foundation for Innovative Diagnostics (FIND)

Cheikh Anta Diop University (CADU)

American Society for Clinical Pathology (ASCP)

Clinical Laboratory Standards Institute (CLSI)

7 Countries (Malawi, Tanzania, Ethiopia, Cameroon, Kenya, Uganda, Zambia

Local Partners

Near POC TB/HIV Diagnostics

TB Diagnostic Test CQI

Evaluating Novel TB Diagnostics

Improving the Laboratory/Clinical Interface

Partnerships for Improved Access to Quality Diagnostics WHO

Global Laboratory Initiative-Africa

ASLM

American Society for Microbiology

FIND

Drug Resistance Quality Assurance and Surveillance

Drug Resistance Data Quality Improvement

Partnerships for Improved Laboratory/Clinical Interface WHO

ASLM

FIND

American Society for Microbiology (ASM)

Senior Laboratory Fellowship Program

Improving Quality of Laboratory Practice (Nurse-Laboratorians)

Equipment Maintenance

Continuous Quality Improvement

Evaluation of New Diagnostics

Partnerships to Support Overarching Initiatives WHO

ASLM

ASM

FIND

ASCP

CADU

CLSI

APHL

Countries

Local Partners

Kenya, Uganda, Tanzania, Malawi, Mozambique, Swaziland

Viral Load Training Tools

Equipment Maintenance

Improved Clinical Uptake and Use

Community/Patient Demand Creation

Specimen Referral Systems

Increased Focus

Ensure Sustainability

Build Capacity Transfer Technology

Administrative and Management Development

Community Laboratory Force

Logistical challenges have been addressed through Periodic on site

mentoring/supervision by the Q-corps

Decrease in turnaround time of proficiency testing program

Capacity building by empowering lower level allows achieving uptake and coverage

Timely data collection and analysis by for implementation corrective actions

Regular site audits using the SPI-RT and mentoring by the Q-corps led to:

Baseline 12 months

in # of testing sites at level 0

84% in # of testing sites at level 3

73%