+ All Categories
Home > Documents > 10 Lymphatic System 09

10 Lymphatic System 09

Date post: 06-Apr-2018
Category:
Upload: hashim-ghazo
View: 224 times
Download: 0 times
Share this document with a friend

of 27

Transcript
  • 8/3/2019 10 Lymphatic System 09

    1/27

    Histology

    ofthe

    LymphaticSystem

  • 8/3/2019 10 Lymphatic System 09

    2/27

    Lymphatic System

    Consists of lymphatic organs,

    tissues, cells and lymph vessels

    It is a part of immune system

    Organs include:Tonsils

    Lymph nodes

    ThymusSpleen

    Tissues in the form of MALT

  • 8/3/2019 10 Lymphatic System 09

    3/27

    Tonsils

    They belong to MALT but considered organsbecause they are partially encapsulated

    Tonsils are covered by epithelium

    They include:1. Palatine tonsils

    2. Pharyngeal tonsils

    3. Lingual tonsils

    4. Tubal tonsils

    Waldrys ring

  • 8/3/2019 10 Lymphatic System 09

    4/27

    Palatine Tonsils

    A pair of them located in the oropahrynx

    Covered by stratified squamous epthelium

    10-20 crypts in each one

    A Sheet of lymphatic nodules and freelymphocytes below the mucosa

    A dense capsule separates it from the

    subjacent tissues

  • 8/3/2019 10 Lymphatic System 09

    5/27

    Pharyngeal Tonsil

    One in the oropharynx covered bypseudostratified columnar epithelium

    Form a thin sheet of lymphoid nodules and

    diffuse lymphocytes No crypts

    Very thin capsule

    Adenoid

  • 8/3/2019 10 Lymphatic System 09

    6/27

  • 8/3/2019 10 Lymphatic System 09

    7/27

    Lingual Tonsils

    They are multiple small ones at the base ofthe tongue

    Covered by stratified squamous epithelium

    One crypt for each tonsil

  • 8/3/2019 10 Lymphatic System 09

    8/27

    Lymph Node

    Shape

    Structure

    Cells

    Cortex

    Medulla

    Lymph circulation

  • 8/3/2019 10 Lymphatic System 09

    9/27

  • 8/3/2019 10 Lymphatic System 09

    10/27

  • 8/3/2019 10 Lymphatic System 09

    11/27

    Thymus Gland

    Location

    Development and Growth

    Structure

    1. Capsule and lobules

    2. Cortex (T-Cell precursor, Reticuoepithelialcells, Macrophages)

    3. Medulla ( T-Cells, Hassall corpuscles Vascularization

    Lymphatic

  • 8/3/2019 10 Lymphatic System 09

    12/27

  • 8/3/2019 10 Lymphatic System 09

    13/27

    T-Cells Differentiation

    It is the site of terminal differentiation andselection of T-lymphocytes

    No receptors on the cell surface of precursor

    cells They divide by mitosis and presented to self

    antigens bound to class I and II MHC on thesurface of epithelial cells, macrophages anddendritic cells

    Positive and negative selections

    Mature T-Cells with receptors leave the thymus

  • 8/3/2019 10 Lymphatic System 09

    14/27

  • 8/3/2019 10 Lymphatic System 09

    15/27

    The Spleen

    Largest lymphoid organ

    Contains large number macrophages

    It is a blood filter

    Structure: capsule, trabeculae, splenic pulp

  • 8/3/2019 10 Lymphatic System 09

    16/27

  • 8/3/2019 10 Lymphatic System 09

    17/27

    Splenic pulp

    Spleen composed of a network of reticulartissue with reticular cells, lymphocytes, otherblood cells, macrophages and APCs

    White pulp Red pulp

  • 8/3/2019 10 Lymphatic System 09

    18/27

    White Pulp

    Blood supply

    Periarterial lymphatic sheath (PALS)

    Lymphoid nodule

    Marginal zine

    Penicillar arteries

  • 8/3/2019 10 Lymphatic System 09

    19/27

    Red Pulp

    Splenic cords supported by reticular fibersand contain T-Cells , B-Cells, macrophages,plasma cells, and many blood cells.

    Splenic sinusoids Closed circulation

    Open circulation

  • 8/3/2019 10 Lymphatic System 09

    20/27

  • 8/3/2019 10 Lymphatic System 09

    21/27

  • 8/3/2019 10 Lymphatic System 09

    22/27

  • 8/3/2019 10 Lymphatic System 09

    23/27

    khb

  • 8/3/2019 10 Lymphatic System 09

    24/27

  • 8/3/2019 10 Lymphatic System 09

    25/27

  • 8/3/2019 10 Lymphatic System 09

    26/27

  • 8/3/2019 10 Lymphatic System 09

    27/27


Recommended