ANNUAL PROGRESS REPORT

Clinical & Chemical Pathology

Reporting period: January 2010

Chair of the Department: Prof. Dr. Ahmed El

Prepared by: Dr. Nelly Abulata

Lecturer of Clinical Pathology

1

ANNUAL PROGRESS REPORT

Clinical & Chemical Pathology

Department

Reporting period: January 2010– December 2010

Chair of the Department: Prof. Dr. Ahmed El

Prepared by: Dr. Nelly Abulata

Lecturer of Clinical Pathology

ANNUAL PROGRESS REPORT

December 2010

Chair of the Department: Prof. Dr. Ahmed El-Saifi

2

Table of Contents

I. Letter from the Chair……………………………………………………………………………………3 II. ClinChem at a glance 1 About us …………………………………….……………………………………………..…….….4 2 Role of the Department………….…………………..………………………………..……….…...5 III. Human Resources……………………………………………………………………………..………6 IV. Organizational Chart………………………………..………….……………………………………....7

1 Deputies……………………………………………………………………………………….…..…..7

2 Advisory Group….…………………..……………………………………………………………...…7

3 Seniors of Each Division…………………………………….……………………………….. ..……..7

4 Secretary General for the Council of the ClinChem Department & Technical Development Officer......7 5 Executive Team…………………………………………………………………………………….....8

6 Executive committees……………………………………………………………………………..…11

V. Laboratory Services we provide…………………………………………..……………………..….....12

1 Background Information…………………………………..……………………………….………......12

2 Total Annual Productivity…………………………………..…………………………………………13

3 Productivity per Lab……………………………………………………………………………….....15

4 Productivity per division……………………………….…………………………………….……..…19 5. Blood Bank Services…………………………………………………………………………….…....19

VI. 2010 Activities & Accomplishments……………………………………..……………………….…20

1. Scientific Research …………………………...…………………………..…………...……………...20 2. Quality Assurance Committee for Laboratory Services……………………………………………….23 3. Quality Assurance Committee for Education………………………………………………………...24 4. ClinChem Conferences……………………………………………………………………………….24 5. Postgraduate Library updated………………………………………………………………………..29 6. Department Website Redesigned and Updated………………………………………………………30

3

I- LETTER FROM THE CHAIR: My goals for the department during 2010 were to rejuvenate and modernize it. Working together with more than 226 faculty members, nearly 30 residents and several hundred Technologists & Technicians, nurses, administrators, and staff who make up the department, we have made rapid strides toward achieving those goals. This year we achieved an overall annual productivity of 4,958,016 tests which could not have been reached without our dedicated manpower (944 employees).

With the appointment of new Heads of Laboratories, Heads of Units and Laboratory Directors and with the creation of an Executive Committee, the Department now has the infrastructure it needs to continue its trajectory. All through 2010 , we continued a steady expansion in our three major missions; Laboratory Services, Teaching & Training and Research Activities.

In the Laboratory service arena , we continued to push ahead with the implementation of Quality Assurance System at Al– Manial Clinical Pathology Laboratory that has replaced our vulnerable home grown system. The construction of both the new Laboratory at the New Maternity Hospital & the New Emergency Hospital are among our top priorities and we anticipate moving into the facility by mid 2011. Teaching activities also remained very strong & the Department's pre– master & pre-doctorate training programs have been modified. In the Research arena , several research projects were funded by the faculty under the roof of the the 2-5yr plan for the Research activities of the Department which involved all 4 specialties of the Department (Hematology, Immunology, Microbiology and Chemistry. As for our international publications, over 20 articles were published by our faculty, several of which were in the high impact journals.

Another source of pride for me and for the department as a whole was that the Department held 2 very successful Scientific Conference s; 1st Annual Scientific Conference “CLINCHEM 2010” from 31 March -2 April with the theme Molecular Biology into the Future & a 2nd CLINCHEM 2010 “Transfusion & Quality updates; Revolution not evolution” on the 24th of October. The Department is building on an extraordinary legacy and has great potential and we plan to make it a yearly event In summary, the Department is on the right path and we look forward to further progress. We hope that in collaboration with our colleagues in the Faculty and Hospital we can upgrade our research, teaching and clinical enterprise in a fashion that melds with the programmatic directions of the University as a whole.

Prof. Ahmed El-Saifi

Chair, Clinical and Chemical Pathology

Department

4

II- CLINCHEM AT A GLANCE: 1- ABOUT US

Mission “Is to provide excellence in Laboratory services, Teaching, Training and Research activities”.

Vision We aspire to be recognized as an Academic Department of excellence to support and enhance the mission and vision of Kasr Al-Ainy Faculty of Medicine, Cairo University.

Objectives 1. To provide excellent laboratory medicine services for the patients of Kasr Al-Ainy

Hospital in a timely & professional manner.

2. To provide an atmosphere of respect for our staff while encouraging continued personal growth, education and development.

3. To provide excellent teaching to a broad spectrum of health care professionals, health care workers and Lab personnel in conjunction with The University.

4. To provide the physical facilities and atmosphere where research activities can flourish, in collaboration with Kasr Al-Ainy Faculty of Medicine and other affiliated institutions.

5. To promote health, treatment and prevention of disease in the diverse population which we serve.

2- ROLE OF THE DEPARTMENT

1. Laboratory services:The Department offers Clinical and Chemical Laboratory services designed to meet the needs of physicians, & patients. The Department has 2 Main Labs at Ala Lab. in each of the following Hospitals; the Specialized Hospital (4th Floor), the Internal Medicine Hospital, the Pediatric Japanese Hospital , the Pediatric Abou Elrish Hospital, King Fahd Hospital, the French Hospital in addition to Emergency Labs that offer the Lab services during the evening and night shifts. The Department is also responsible for the Technical supervision of the Blood Bank.

2. Teaching & Training:

The Department is committed to providing strong and balanced Teaching and Training programs mainly to Postgraduate students, principally in the Master and Doctorate degrees in Clinical and Chem(Hematology, Immunologalso partly involved in the Teaching & Training of postgraduate students of other Departments enrolled in Master, Diplomas & Doctorate degrees in addition it provides instructional courses to the 6t

3. Research activities:

The Research Faculty members within the Department are nationally recognized. The Research ranges from clinical to basic Research, with an emphasis on Hematologic Malignancies, Virology & Molecular Genetics.

Teaching &

5

ROLE OF THE DEPARTMENT

1. Laboratory services: The Department offers Clinical and Chemical Laboratory services designed to meet the

patients. The Department has 2 Main Labs at Ala Lab. in each of the following Hospitals; the Specialized Hospital (4th Floor), the Internal Medicine Hospital, the Pediatric Japanese Hospital , the Pediatric Abou Elrish

ahd Hospital, the French Hospital in addition to Emergency Labs that offer the Lab services during the evening and night shifts. The Department is also responsible for the Technical supervision of the Blood Bank.

Teaching & Training:

nt is committed to providing strong and balanced Teaching and Training programs mainly to Postgraduate students, principally in the Master and Doctorate degrees in Clinical and Chemical Pathology tailored to each student (Hematology, Immunology, Microbiology or Chemical Pathology). The Department is also partly involved in the Teaching & Training of postgraduate students of other Departments enrolled in Master, Diplomas & Doctorate degrees in addition it provides instructional courses to the 6th year students.

3. Research activities:

The Research Faculty members within the Department are nationally recognized. The Research ranges from clinical to basic Research, with an emphasis on Hematologic Malignancies, Virology & Molecular Genetics.

Laboratory

Services

ResearchTeaching &

Training

The Department offers Clinical and Chemical Laboratory services designed to meet the patients. The Department has 2 Main Labs at Al-Manial Hospital,

a Lab. in each of the following Hospitals; the Specialized Hospital (4th Floor), the Internal Medicine Hospital, the Pediatric Japanese Hospital , the Pediatric Abou Elrish

ahd Hospital, the French Hospital in addition to Emergency Labs that offer the Lab services during the evening and night shifts. The Department is also

nt is committed to providing strong and balanced Teaching and Training programs mainly to Postgraduate students, principally in the Master and Doctorate

ical Pathology tailored to each student subspecialty . The Department is

also partly involved in the Teaching & Training of postgraduate students of other Departments enrolled in Master, Diplomas & Doctorate degrees in addition it provides

The Research Faculty members within the Department are nationally recognized. The Research ranges from clinical to basic Research, with an emphasis on Hematologic

6

III. HUMAN RESOURCES

The Department has a total manpower of around 944 employees. This comprises: · 287 Doctors ; 226 Faculty members, 36 Specialists & 27 Residents

· 369 Technologists & Technicians

· 59 Nurses

· 131 Administration

· 96 Cleaners

226

36

27Doctors

Faculty staff

Specialists

Residents

290

369

59

131

96

0

50

100

150

200

250

300

350

400

Human Resources

Doctors

Technologists & Technicians

Nurses

Administration

Cleaners

IV- ORGANIZATIONAL CHARTThe Organizational structure has been modified and effective teams have been built aiming to introduce the “we” culture and a more qua litative workplace.

1. Deputies:

1. A Deputy for Scientific Research Development Affairs: (Prof. Dr. Ali Shams ElDin)

Who is in charge of the overall management for planning and coordinating multiple research teams and development activities and processes at a research and development unit/group level that will eventually lead to the international recognition of our Department that will in turn participate in the International recognition of the of Kasr Altogether with a team of representatives of each specialty MSc & MD protocols before they are officially registered.

2. A Deputy for Teaching, Training & staff relocation: (Prof. Dr. Azza Mostafa)

Who is in charge of managing the teaching & training package that encomelements in order to maintain a motivated and skilled workforce and to fulfillorganization. This Deputy is also in charge of the need.

3. A Deputy for Examination A

Who is in charge of managing and liaising with the heads of the units all the matters related to the examinations including schedules, exam development & examination boards formation.

Chair of the Clinical & Chemical Pathology

Deputy for

Scientific

Research

Affairs

Team with

representatives of

all specialties

7

ORGANIZATIONAL CHART The Organizational structure has been modified and effective teams have been built aiming to introduce the “we” culture and a more qua litative workplace.

Scientific Research Development Affairs: (Prof. Dr. Ali Shams ElDin)

Who is in charge of the overall management for planning and coordinating multiple research teams and development activities and processes at a research and development unit/group level that will eventually lead to the international recognition of our Department that will in turn participate in the International recognition of the of Kasr Al-Ainy Faculty of Medicine. This Deputy

resentatives of each specialty is responsible for the validation of all the MSc & MD protocols before they are officially registered.

A Deputy for Teaching, Training & staff relocation: (Prof. Dr. Azza Mostafa)

Who is in charge of managing the teaching & training package that encomelements in order to maintain a motivated and skilled workforce and to fulfill

is Deputy is also in charge of the relocation of staff to & from labs according to

A Deputy for Examination A ffairs: (Prof. Dr. Safaa Al-Karaksy)

Who is in charge of managing and liaising with the heads of the units all the matters related to the examinations including schedules, exam development & examination boards formation.

Chair of the Clinical & Chemical Pathology

Dept

Team with

representatives of

all specialties

Deputy for

Teaching,

Training Staff

Positioning &

relocation Affairs

Team with

representatives of

all specialties

Deputy for

Examination

Affairs

Team with

representatives of

all specialties

The Organizational structure has been modified and effective teams have been built

Scientific Research Development Affairs: (Prof. Dr. Ali Shams ElDin)

Who is in charge of the overall management for planning and coordinating multiple research teams and development activities and processes at a research and development unit/group level that will eventually lead to the international recognition of our Department that will in turn

Ainy Faculty of Medicine. This Deputy responsible for the validation of all the

A Deputy for Teaching, Training & staff relocation: (Prof. Dr. Azza Mostafa)

Who is in charge of managing the teaching & training package that encompasses both these elements in order to maintain a motivated and skilled workforce and to fulfill the needs of the

the relocation of staff to & from labs according to

Who is in charge of managing and liaising with the heads of the units all the matters related to the examinations including schedules, exam development & examination boards formation.

Deputy for

Examination

Affairs

Team with

representatives of

all specialties

8

2. Advisory Group

The Advisors are composed and structured in order t o provide non-binding but informative guidance to the Chair that serves as an ally during discussions when needed. The advisory group includes:

· Prof. Dr. Omnia Yousef: Emeritus Prof. of Chemical Pathology

· Prof. Dr. Souhair Helal: Emeritus Prof. of Clinical Pathology: subspecialty Microbiology

· Prof. Dr. Naguib Zohair: Prof. of Clinical Pathology: subspecialty Hematology

3. Seniors of each Division

The Department has 4 specialties and accordingly 4 seniors:

· Prof. Dr. Safaa Al-Karaksy: Senior Immunologist

· Prof. Dr. Tayssir Eyada: Senior Hematologist

· Prof. Dr. Amani El-Kholy: Senior Microbiologist

· Prof. Dr. Fatma El-Mougy: Senior Chemical Pathologist

4. Secretary General for the Council of the ClinChem Department & Technical Development Officer (Dr. Nelly Abulata)

As the Secretary General of the Council she moderates the Council and several Departmental Committees. And as the Technical Development Officer she collaborates with Laboratory Managers, Heads of Laboratories, Heads of Units and other Project Managers in the restructuring of the organizational system, developing decentralization and defining job responsibilities within the Department aiming to ensure that the objectives and performance plans of the Department and Faculty were being met ; 5. Executive team Is composed of the Laboratory Directors (Administra tive affairs), the Heads of Labs & Heads of Units (Technical Affairs) that direct, sup ervise and coordinate the functions and activities of the Hospital laboratories

9

Main Lab at Manial Hospital

Laboratory Head of Lab. (Technical)

Lab Director (Administrative)

Head of Hematology Unit

Head of Immunology Unit

Head of Genetics unit

Head of the Molecular Unit

Head of Microbiology Unit

Manial Clinical Pathology Lab.

Prof. Safa Al-Karaksy

Prof. Dr. Mona Salah

Prof. Dr. Nabil El-Danasoury

Prof. Dr. Safaa Al-Karaksy

Prof. Dr. Hala Farawela

Prof. Dr. Mona Salah

A. Prof. Dr. Nada Nawar

Laboratory Head of Lab. (Technical)

Lab Director (Administrative)

Head of Trace Elements Unit

Head of Chemistry Routine Unit

Head of Proteins Unit

Head of Hormones Unit

Manial Chemical Pathology Lab.

Prof. Dr. Fatma El-Mougy

Prof. Dr. Badawy Al-Khouly

Prof. Dr. Badawy Al-Khouly

Prof. Dr. Lamia Mansour

Prof. Dr. Sahar Abdel-Atty

Prof. Dr. Nadida Gohar

10

Other Hospital based labs

Laboratory Head of Lab. (Technical)

Lab Director (Administrative)

Head of Hematology

Head of Immunology

Head of Microbiology

Head of Chemical Pathology

Internal Medicine Hospital Lab.

Prof. Dr. Laila Hegazy

Dr. Magda Negm Prof. Dr. Laila Hegazy

A .Prof Dr. Nancy El-Guindy

A. Prof. Dr. Hany Hussein

Japanese Hospital Lab.

Prof. Dr. Hanaa Arnaout

TBD Prof. Dr. Hanaa Arnaout

Dr. Safa Meshal

A.Prof. Dr. Mona Mohie El-Din

Prof. Dr. Amal Abdel Wahab

Abou -Elrish Mounira Hospital Lab.

Prof. Dr. Iman El-Mahgoub

Prof. Dr. Nesrine El-Gharabawy

Prof. Dr. Nesrine El-Gharabawy

Prof. Dr. Maha Gaafar

Prof. Dr. Heba Sharaf El-Din

Specialized Hospital Lab. (4 th floor)

Prof. Dr. Tayseer Eyada

Dr. Sheriene Abdel-Kader

Prof. Dr. Tayseer Eyada

Prof. Dr. Sheriene Mahmoud

Prof. Dr. Souhair Helal

Prof. Dr. Sahar Abdel Atty

French Hospital Lab.

Prof. Dr. Azza Mostafa

Dr. Hanan Ibrahim

Prof. Dr. Naguib Zoheir

Prof. Dr. Tagreed Gaafar

Prof. Dr. Amani El Kholy

Prof. Dr. Ola El-Sissy

King Fahd Hospital Lab.

Prof. Dr. Hala Sheebah

Psychiatric Hospital Lab.

Prof. Dr. Badawy Al -Khouly

New ER Hospital Lab

Prof. Dr. Badawy Al -Khouly

Maternity Hospital Lab.

A. Prof. Dr. Iman Mandour

Assistant Prof. Aya Nassef

TBD TBD A. Prof. Dr. Iman Mandour

Sharm ElSheikh Int. Hosp.

Assistant Prof. Mohamed Shehata

Blood Bank Prof. Dr. Mervat Al-Ansary

Dr. Abeer Reehan

11

6. Executive Committees 1. Executive Committee for Laboratory Affairs: As things evolved over time, we found that it was necessary to form an Executive Committee, which has been meeting every month for the past couple of months usually one week prior to the Board meeting of the Department. At those meetings, the Executive Committee reviews the major issues facing the Department, weighing pros and cons and making preliminary decisions, to be ratified by the Board as a whole at the actual Board meeting of the Department. The Committee is comprised of: 1. The Chair of the Department: Prof. Ahmed El-Saifi 2. The Head of the Laboratories

· Prof. Azza Mostafa · Prof. Safaa Al-Karaksy · Prof. Mervat Al-Ansary · Prof. Tayssir Eyada · Prof. Fatma El-Mougy · Prof. Hanaa Arnaout · Prof. Laila Hegazy · Prof. Eman ElMahgoub · Prof. Hala Sheebah

3. The Laboratory Directors · Prof. Badawy Al-Kholy · Prof. Mona Salah · Prof. Nesrine ElGarabawy · Ass. Prof. Lobna ElMessery · Dr. Magda Negm · Dr. Abeer Reehan · Dr. Sherine Abdel-Kadr

4. Other members: · Prof. Sherief Naseh Amin (Deputy Head of the General Hospitals) · Prof. Amani Al-Kholy (Most Senior Microbiologist) · Prof. Omnia Youssef (Advisory Group member) · Prof. Souhair Helal (Advisory Group member)

2. Executive Committee for Blood Bank Affairs: Since the Department is responsible for the Technical supervision of the Blood Bank an Executive Committee for the Blood Bank has also been formed which will review and discuss any issues facing the Blood Bank. The Committee will start meeting on monthly basis starting from next month, typically one week prior to the Hospital Board meeting. The Committee is comprised of:

1. The Chair of the Department (Prof. Ahmed El-Saifi) 2. The Head of the Blood bank (Prof. Mervat Al-Ansary) 3. The Blood Bank Director (Dr. Abeer Reehan) 4. The Deputy Head of the General Hospitals (Prof. Sherief Naseh Amin) 5. Other members (to be determined).

12

V- LABORATORY SERVICES WE PROVIDE

1. Background information:

Our Laboratories provide an extensive menu of routine & specialized laboratory tests to the patients who seek care at Kasr Al-Ainy Hospitals.

Lab Divisions

· Hematology Laboratory

· Clinical Immunology & Molecular Diagnostics

· Clinical Microbiology

· Clinical Chemistry

13

2. Annual Productivity:

Hospital Lab

Relevant Hospital Info Total

Annual

Lab

Productivity

% out of the total

annual Productivity of

all labs

Inpatient

beds

Average Outpatients clinic cases per month

Average ER cases per month

Manial Labs

2,018 40,980 15,067 1804809

37%

Japanese Lab 421 8700 4,876 553410

11%

Abou El -Rish Lab

307 23,477 8,539 473044

10%

Internal Medicine Lab.

357 2175 1,268 553298

11%

4th floor Lab 277 No Clinic 180 268033

6%

King Fahd Lab 111 514 No ER 134430

3%

French Lab

1,200 Not available

Not available

1070644

22%

14

37%

22%

11%

11%

10%

6% 3%

% out of the total annual productivity of

2010

Manial

French

Internal Medicine

Japanese

Abou ElRish

4th floor

King Fahd

4,958,016

(130)

1,804,809

(47)

1,070,644 (30)

553,410

(21)

553,298(33)

473,044(24)

268,033(2)

134,430(10)

50,1740

1000000

2000000

3000000

4000000

5000000

6000000

Tota

l n

o.

of

test

s &

Do

cto

rs

Laboratory

2010 Annual productivity

15

3. Productivity per Lab 1. Al-Manial Clinical & Chemical Pathology Labs:

We have 2 labs at Al-Manial Hospitals one on the ground floor (Clinical Pathology) and one on the 2nd floor (Chemical Pathology) with a total no. of employees of 328.

The Clinical Pathology Laboratory employs 169 people; 57 Faculty Staff (17 Emeritus Professors, 13 Professor, 2 Assistant Professors , 7 Lecturers, 6 Assistant Lecturer & 5 Demonstrators), 5 Specialists, 5 Residents, 14 Technologists, 47 Technicians, 6 Nurses, 20 Administration & 15 Cleaners.

The Chemical Pathology Laboratory employs 159 people; 61 Faculty Staff (10 Emeritus Professors, 11 Professor, 8 Assistant Professors , 12 Lecturers, 17 Assistant Lecturer & 3 Demonstrators), , 3 Residents, 14 Technologists, 56 Technicians, 4 Administration & 16 Cleaners.

369530

37402 15571 739

1381567

1804809

0

200000

400000

600000

800000

1000000

1200000

1400000

1600000

1800000

2000000

Manial Labs

Hematology

Immunology

Microbiology

Parasitology

Chemical Pathology

Total

16

2. Japanese Lab:

The Laboratory employs 83 people; 25 Faculty Staff (8 Professor, 6 Assistant Professors, 4

Lecturers & 7 Assistant Lecturer), 5 Residents, 1 Technologists, 39 Technicians, 13

Administration & 5 Cleaners.

3. Abou El-Rish Lab:

The Laboratory employs 67 people; 18 Faculty Staff (5 Professor, 3 Assistant Professors , 6

Lecturers, 3 Assistant Lecturer & 1 Demonstrators), 10 Specialists, 5 Residents, 9

Technologists, 15 Technicians, 9 Administration, 2 Nurses & 6 Cleaner

120205

13665 12283 13305

393953

533410

0

100000

200000

300000

400000

500000

600000

Japanese Lab

Hematology

Immunology

Microbiology

Parasitology

Chemical Pathology

Total

103166

12594 21993 15227

320064

473044

050000

100000150000200000250000300000350000400000450000500000

Abou ElRish ElMounira Lab

Hematology

Immunology

Microbiology

Parasitology

Chemical Pathology

Total

17

4. Internal Medicine Lab:

The Laboratory employs 42 people; 14 Faculty Staff (3 Emeritus Professor, 3 Professor, 1

Assistant Professors , 3 Lecturers & 5 Assistant Lecturer), 2 Specialists, 5 Residents, 10

Technologists, 6 Technicians, 4 Administration & 2 Cleaners.

5. 4th floor Lab:

The Laboratory employs 53 people; 11 Faculty Staff (1 Emeritus Professors, 5 Professor , 2

Assistant Professors, 3 Lecturers), 3 Specialists, 10 Resident Specialists, 8 Technologists, 10

Technicians, 9 Administration, 4 Nurses & 6 Cleaners.

553353220 1029 3125

490319553298

0

100000

200000

300000

400000

500000

600000

Internal Medicine Lab

Hematology

Immunology

Microbiology

Parasitology

Chemical Pathology

Total

400574929 3660 3327

216960

268033

0

50000

100000

150000

200000

250000

300000

4th floor Lab

Hematology

Immunology

Microbiology

Parasitology

Chemical Pathology

Total

18

6. King Fahd Lab:

The Laboratory employs 21 people; 1 Faculty Staff (1 Professors), 1 Specialists, 7

Technologists, 5 Technicians, 5 Nurses, 1 Administrative Secretaries & 1 Cleaner.

7. French Lab The Laboratory employs 223 people; 45 Faculty Staff (4 Emeritus Professor, 11 Professor,

11 Assistant Professors, 13 Lecturers, 4 Assistant Lecturer), 2 Senior Registrars, 17

Technologists, 73 Technicians, 7 Nurses, 56 Administration & 23 Cleaners

246929837 2513 5055

92325

134430

020000400006000080000

100000120000140000160000

King Fahd Lab

Hematology

Immunology

Microbiology

Parasitology

Chemical Pathology

Total

15946437317 18285 19108

1480068

1714242

0200000400000600000800000

10000001200000140000016000001800000

French Lab

Hematology

Immunology

Microbiology

Parasitology

Chemical Pathology

Total

19

4. Productivity per division

5. Blood Bank Services

· Blood Bank Profile: The Blood Bank employees approximately 128 people who are involved in Blood Donation, Blood Processing and Hemapheresis.

· Blood Bank Structure: • The Head of the Blood Bank : Prof. Dr. Mervat Al-Ansary • Administrative Director: Dr. Abeer Reehan. • The Team includes: 7 Specialists , 2 Residents, 6 Financial officers , 2 Administrative

Officers, 2 Social Officers, 1 Statistician, 5 Technologists, 30 Technicians, 35 Nurses, 7 Administrative Secretaries, 11 Clerks, 22 Cleaners

. 2010 Blood Bank services

16%

2%

1%

81%

Hematology

Immunology

Microbiology

Chemical Pathology

Total Rejected Screened HbsAg HCV HIV Syphilis Plasma Cryo Outpatient-

clinic 20099 218 19878 325 1098 31 57 14387 3523 Donation campaign 30075 917 29140 252 928 49 65 25640 ------

Total 50174 1135 49018 577 2026 80 122 40027 3523

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VI- 2010 ACTIVITIES & ACCOMPLISHMENTS 1- Scientific Research

· Project Profile: The aim of this project is to develop a plan for the Research activities of the Department over the coming 2-5 yrs which will involve all the specialties of the Department. The project will hopefully lead to the international recognition of the Department that will in turn participate in the International recognition of Kasr Al-Ainy Faculty of Medicine . Project starting date : 27/08/09 · Project structure: Project Leader: Prof. Ali Shams El-Din Project Team Members: Prof. Azza Mostafa, Prof. Taghrid Gaafar, Prof. Amani El-Kholy, Prof. Fatma El-Mougy, Prof. Mona Wasif, Prof. Hala Farawela, Prof. Afaf ElBannah, Prof. Iman Mansour, Prof. Hala Ali, Prof. Hala Gabr, Prof. Sahar Abdel Atty Ethical committee Members: Prof. Azza Mostafa, Prof. Dr. Safaa Al-Karaksy, Prof. Amani El-Kholy, Prof. Fatma El-Mougy Key research subjects 1. HCV 2. Stem Cell Research 3. Neurodegenerative diseases 4. Infection prevention and control 5. Molecular basis of Hematological disorders 6. Juvenile Diabetes Mellitus. . Accomplishments to date: 1. Planning process: Done 2. Implementation: Done 3. Follow: in process . Research Grants: 1. STDF grant : "Stem Cell Therapy in Endstage liver cell failure". Principle investigator: Prof. Dr. Hala Gabr 2. Cairo University Grant: "Isolation and identification of Limbal Stem Cells". Co-investigator Prof. Dr. Hala Gabr

. Research Awards: 1. A. Prof Heba Abdel Razik has won the Award ة ا��و�� ا�������� ��� “ ” 2. Prof. Dr.Hala Gabr won the “University Award for the High impact factor award ” 3. Dr. Dina Ahmed Mehaney has been awarded “Best MD thesis in Cairo University”

21

. Several projects received funding from the Facult y among which are: (>200,000LE)

1. Telomerase activity and hTERT mRNA expression in lymphoid leukemias (Shahira kamal,

Sarah Adel) Fund value 38,900LE

2. Detection of IL18 and its m-RNA expression in idiopathic thrombocytopenic purpura (Iman Abdel Mohsen) Fund value 36,000 LE

3. Human brain and acute leukemia cytoplasmic (BAALC)gene andETS related genes (ERG) expression in acute myeloid leukemia (Amal Soliman Nasr) Fund value:14,400L.E

4. 6q aberrations in lymphoproliferative disorders (Dalia Gamil) Fund value:26,237LE

5. Expression of TSC1 and TSC2 gene in the newly diagnosed acute leukemia (Zeinab Ali) Fund value43.580

6. Study of the telomerase enzyme mutation in Acquired Aplastic Anemia in Egyptian children

(Prof. Dr. Mervat Al-Ansary, Prof. Dr. Amal El-Beshlawy, Prof Dr.Mona El Tagui.Assistant, Prof. Dr. Mona Hamdy, Dr. Nelly Abulata, Dr. Fadwa Saeed) Fund value: 21,800

7. Genetic Polymorphism of Oxidative stress genes and the risk of non-Hodgkin’s Lymphoma and its relevance to HCV infections (Prof. Dr. Hala Farawela, Prof. Dr. Hamdy ElZawam, Prof. Dr. Somia Abdel Rahmna, A. Prof. Aya Nassef, A.Prof. Mervat Khorshied, A.Prof. Heba Gouda, Dr. Iman Shaheen, Dr. Nelly Abulata) Fund value 21, 790 LE

8. Prognostic relevance of pSTAT5 expression in acute myeloid Leukemia (A. Prof. Heba Hassan Abou Elewa) Fund value13 ,140 L.E.

9. Study of ex-vivo expanded bone marrow mesenchymal stem cells in aplastic anemia patients and the role of transcriptional factor gata-2 in fatty marrow replacement (A. Prof. Doha Abdel Hamid) Fund value 20,765 L.E.

. International publications

1-Association Between The Monocyte Chemoattractant Protein-1 (MCP-1) 2518G/A Gene Polymorphism And Acute Myocardial Infarction Patien ts Among Egyptian Population. ( El Mahgoub, Iman R; Afify, Reham A; Aal, Asmaa A Abdel; Beda, Dalia) . Coagulation Fibrinolysis J 2- Study of the Association of CYP2D6*4 Polymorphis m with the Risk of Chronic Myeloid Leukemia (Sahar K Hussein, Asmaa A Abd El-Aal, Reham A. Aleem Afify) Journal of infection control. 3- AnnexinV and adhesion molecules expressions on e rythrocytes in sickle cell anemia patients treated with hydroxyurea (Nermeen el Desoukey, Hend el Sherbiny, Dalia G. Amin) The Arab journal of laboratory medicine 4- Clinical relevance of angiopoietin-1, angiopoiet in-2, and their receptor Tie-2expression in acute myeloid leukemia (Safaa M. El Karaksy . Nancy M. El Guindy . Heba M. Gouda .

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Mervat M. Khorshied . Iman A. Shaheen . Reham E. Abu Khalil . Noha Y. Ibrahim. Comparative Clinical Pathology 5-The clinical significance of methylenetetrahydrof olate reductase (MTHFR) polymorphisms in acute lymphoblastic leukemia (Hanaa H. Arnaout . Mervat M. Khorshied, Iman A. Shaheen . Heba M. Gouda . Noha Y. Ibrahim . Naglaa F. Koura.) . Comparative Clinical Pathology 6- Portal vein thrombosis and haematemesis in chron ic liver disease. Are P-selectin and PSGL-1 clues? (Hoda A. Sadek , Bothina A. Madkour , Salwa M. Toima , Abeya F. Saleh , Iman A. Shaheen ,Rabab F. Yaseen, Emad El-Din A. Bayoumi) Arab Journal of Gastroentrology 7-The osteogenic differentiation potentials of umbi lical cord blood haematopoietic stem cells . Mervat M. Khorshied ; Heba M. Gouda ; Iman A. Shaheen Tarek N. Al Bolkeny. Comparative Clinical Pathology. 8-Identification and clinical evaluation of the recep tor for Hyal-uronic acid mediated motility (RHAMM/CD 168) in AML patients: Khorshied M., Omar D. Pan Arab Journal of Oncology 9- Nucleophosmin gene mutation in acute myeloid leu kemia patients. Khorshied MM, Said WA, Shaaban HA. Saudi Med J 10- Autologous melanocyte–keratinocyte suspension i n the treatment of vitiligo . BM El-Zawahry, NS Zaki, DA Bassiouny, RM Sobhi, A Zaghloul, MM Khorshied and HM Gouda. JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY. 11- Detection of CXCL12 Gene Polymorphism and CXCR4 Expression in Egyptian Acute Myeloid Leukemia Patients ( Aisha Abd El-Rahman, Samah Abdel-Hamid, Manal Makhlouf, Nermine El-Desouky, Mohamed Al-Feky and Sherif Yousri. The Journal of American Science 12-Detection of XRCC1 gene Polymorphisms in Egyptia n Patients with Acute Myeloid Leukemia( Mona Salah El-Din, Hanan Raslan, Samah Abdel-Hamid, Manal Makhlouf) Comparative Clinical Pathology 13- Mesenchymal Stem Cell (MSC) Transfusion as a No vel Immunosuppressive Regimen with Possible Induction of Microchimerism. (Gamal Saadi, Mervat El-Ansary, Samah Abd El-Hamid, Eman Abd EL-Aziz) Global Science of Books 4(2). 14- Dendritic Cell Vaccine as an Adjuvant Therapy i n the Treatment of Chronic Myeloid Leukemia. Mervat El-Ansary, Mervat Mattar, Shereen Kamel, Samah Abd El-Hamid, Rania Abou Elnour Global Science of Books 4(2

15- Phase I Trial: Mesenchymal Stem Cells Transplantati on in End Stage Liver Disease .M El-Ansary, Sh Mogawer, I Abdel-Aziz, S Abdel-Hamid. Journal of American Science. 6(12):135-144

16- Cytogenetic study of the effect of Schistosoma mansoni infection on human peripheral blood lymphocytes and the role of B-carotene and vi tamin E in modulating this effect .Mervat El Ansary, Iman Khaled, Abeya Fouad, Ola Mahmoud, Emad Baioumi, Heba Abo Bakr. Journal of American Science.

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17- Celiac Disease in Children and Adolescents with Aut oimmune Hepatitis : a Single – centre Experience .Mortada El-shabrawi ,Hanna El-Karasy,Nabil Mohsen ,Mona Isa ,Mohammed Al-Biltagi , Mervat El-Ansari . Journal of Tropical Pediatrics Advance Access 18- Flow cytometric detection of leukemic stem cells ( LSCs) in Egyptian pediatric B-acute lymphoblastic leukemia (Manal W. El-Masry & Mervat M. Khorshied & Iman A. Shaheen & Nelly N. Abulata & Tarek A. Hashem) Comparative Clinical Pathology 19- Case Control Series of Intrathecal Autologous Bone Marrow Mesenchymal Stem Cell Therapy for Chronic Spinal Cord Injury . Nirmeen A. Kishk, Hala Gabr, Sherif Hamdy,Lamia Afifi , Noha Abokresha, Hayam Mahmoud,Ahmed Wafaie, and Dalia Bilal. Neurorehabil Neural Repair July 26, 2010. DOI: 10.1177/1545968310369801 20- Feasibility, Safety, and Efficacy of Directly Transplanting Autologous Adult Bone Marrow Stem Cells in Patients With Chronic Traumati c Dorsal Cord Injury . A Pilot Clinical Study. Osama S. Abdelaziz, Ahmed Marie, Mohamed Abbas, Mohamed Ibrahim, and Hala Gabr. Neurosurg Q 2010;20:216–226. 21- Autologous Mesenchymal Stem Cells for Neuro-Regener ation After Traumatic Spinal Cord Injury: A Comparison Between Bone Marrow and Peripheral Blood Populations. Abo El-Kheir W, Gabr H, Awad MR, von Wild K, and Ramadan M. American Journal of Neuroprotection and Neuroregeneration Vol. 2, 1–8, 2010 IF: 6.2 & received the University Award for the Hi gh impact factor award

2- Quality Assurance for Laboratory service

. Project profile: The aim of Quality assurance project (QA) is to ensure that the Laboratories of Cairo University Hospitals provide services that meet the best quality standards. . Project starting date : 27/08/09 . Project Structure: Project Leader: Dr. Ola Khashaba Project Team Leaders (2009/2010) : Prof. Safaa Al-Karaksy (Immunology), Prof. Naguib Zoheir (Hematology), Prof. Mona Wasif (Microbiology),Prof. Lamiaa Mansour (Chemical Pathology) Project Team Members : Relevant staff members in each team. . Accomplishments during 2009/ 2010 at Main Laboratories (Al-Manial Clinical Pathology Lab., N.B. Chemical P athology Lab. joined the project late by mid -year 2010)

1. Initial assessment & Gap analysis in Al-Manial Lab using prepared checklists: Generic & specific

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2. Team building 3. Awareness & Training sessions: For doctors and technicians 4. Development of standardized forms to be used in all departments including: Q.C,

Calibration, Maintenance, Temperature control, Refrigerator content and maintenance card; in addition to special forms for some procedures e.g. ELISA, manual procedures, and Cytochemistry.

5. Implementation of the developed forms in all relevant previously mentioned departments with varying degree of compliance according to the results of the internal audits performed by the project leader and the submitted audit reports.

6. Two formal announced internal audits were performed one on March 2010 and the second on June 2010 (which included the Chemical Pathology lab.).Additional random audits were performed through informal communication with the process owners as one way of improving their performance.

7. Work is in progress to fully implement the Intranet through which the quality control will be automated.

8. Work is in progress to teach doctors in charge of developing and interpreting the control charts (or just how to read them after automation) and using the Westgard rules.

9. Training sessions and meeting with the new teams were regained by the end of the year 2010.

3- Quality Assurance for Education · Project Profile: The aim of this project is to check how well the Department meets it’s responsibilities, identifies good practice and makes recommendations for improvement. . Project starting date : 1/10/10 · Project structure: Project Leader: Prof. Hala Sheebah Project Coordinator: A. Prof Mervat Khorshied Project Team Members: Prof. Hala Ali, Prof. Nehad Mosaad, A.Prof. Maha Gaafar, A.Prof. Aya Nassef, A. Prof Mervat Khorshied, Dr. Safa Meshaal, Dr. Rania Darwish, Dr. Safaa ElGabarty . Accomplishments to date: 1. Authentification of all the committees within the department 2. Gathering available & preparing unavailable job description for all the types of jobs & roles 3. Following up on the efficiency of teaching & training via evaluation surveys. 4. Maintaining the system & following up on complaints 5. Listing of the no. registered master & doctorate thesis’s 6. Listing of the no. of the number of projects that have received funding from the faculty.

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4- Training courses/ workshops: • Training course for “Screening metabolic disorders by Tandem Mass Spectrometry”

Organized via a collaboration between the Chemical Pathology team (Prof. Dr. Fayza A Hassan Prof. Dr. Fatma El-Mougy Prof. Dr. Sahar Abdel-Atty Prof. Dr. Iman Mandour A. Prof.Dr. Marian Morgan Dr. Dina Mehaney Dr. Mohammed A. Monem) and the Pediatric Endocrinology team at Pediatric Hospital

• Workshop in collaboration with ESPCR lead by Prof. Dr. Hala Gabr on: " Isolation, characterization and tagging of Adipose-derived stem cells“

• 2 workshops Lead Prof. Amani Al-Kholy & her Team ( A.Prof. Mervat Gaber Al-Anainy, A.Prof. Mona Mohieddin Abdel Halim, Dr. Mariam Adel, A. Lecturer Mai Sherief) in collaboration with NAMRU-3 & USA-CDC:

1. Survey of antimicrobial consumption in Cairo Univ Hospitals

2. Use of PDA in Clinical surveillance for healthcare associated infections in ICUs

• Workshop on “Molecular Diagnosis of Acute Respiratory infections”; lead by Prof. Amani Al-Kholy, Prof. Mona Salah, A. Prof. Iman AbdelRahman in collaboration with NAMRU-3

4- ClinChem Conferences The Department held 2 very successful Scientific Conference s; the 1st CLINCHEM 2010 Conference" Molecular Biology: Into the future" held from 31st of March -2nd of April at CICC had a record-breaking attendance of nearly 600 participants in the could not have been achieved without the support of sponsors like SIEMENS,EL-DAWLEYA,TECHNOSCIEN, CLINILAB,ETICO,ENDOMEDIX&ULTRADIAGNOSTICS. In response to the feedback we received from our attendees and sponsors we decided to launch the 2nd CLINCHEM 2010 Conference "Transfusion Medicine & Quality updates: Revolution not evolution" that was held on the 24th of October, 2010 at the Learning Resources center at Kasr Al-Ainy Faculty of Medicine, Cairo University which was another great success thanks to sponsors such as DIA MED, FUTURE HORIZON, SPECTRA, SIEMENS & INTERPHARM. Our goals for the Conferences were simple, but bold: to bring together successful Laboratory Medicine professionals, Clinicians, Scientific and Medical publishers and Biotechnology companies, to discuss opportunities and challenges in the exciting field of Genetics & Tissue Engineering, by doing so, share the most up-to-date strategies explore recent developments and identify fruitful avenues for further research to enhance the Quality of our Healthcare Services.

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1st ClinChem Conference 2010 “Molecular Biology: Into the future" : 31st of March -2nd of April at Cairo International Conference Center General info

Conference President Prof. Ahmed El-Saifi

Vice President Prof. Azza Mostafa

Secretary General Prof. Fatma El-Mougy

Dr. Nelly Abulata Conference Coordinator

· Organizing Committee

Prof. Omnia Youssef Prof. Safaa Al-Karaksy Prof. Amani Al-Kholy Prof. Hala Farawela Prof. Mona Salah Prof. Sahar Abdel Atty

A. Prof. Mervat Gaber A. Prof. Noha Shaheen Dr. Mervat Khorshied Dr. Nelly Abulata Dr. Heba El-Baz Dr. Riham El-Sayed

Scientific Program Committee

Hematology Committee Prof. Ali Shams ElDin Prof. Azza Ahmed Prof. Naela Omran Prof. Tayssir Eyada Prof. Hanaa Arnaout

Microbiology Committee Prof. Walaa Gad Prof. Souhair Helal Prof. Amani Al-Kholy Prof. Mona Wassif Prof. Nevine El-Rasheedy

. Immunology Committee Prof. Nawal Affifi Prof. Nehad El-Sheemy Prof. Safaa Al-Karaksy Prof. Taghrid Gaafar Prof. Mervat Al-Ansary

Chemistry Committee Prof. Omar Al-Roubi Prof. Omnia Youssef Prof. Mona Salem Prof. Fayza Abdel Hamid Prof. Nadida Gohar

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ENTRANCE TO THE HALL

PANEL

AUDIENCE

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2nd ClinChem Conference 2010

"Transfusion Medicine & Quality updates: Revolution not evolution" that was held on the 24th of October, 2010 at the Learning Resources center at Kasr Al-Ainy Faculty of Medicine General info

Prof. Dr. Ahmed El-Saifi Conference President

Prof. Dr. Mervat Al-Ansary Conference Vice President

Dr. Nelly Abulata Conference Coordinator

Organizing Committee Prof. Dr. Hala Gabr A. Prof. Nermeen El-Dessouky Dr. Rania Zayed Dr. Heba El-Baz Dr. Heidi Goubran

Scientific Program Committee Prof. Dr. Nawal Afifi Prof. Dr. Azza Mostafa Prof. Dr. Safa Al-Karaksy Prof. Dr. Mervat Al-Ansary Prof. Dr. Azza Abou El-Enain Prof. Dr. Amaal El-Beshlawy Prof. Dr. Mervat Mattar Prof. Dr. Fikri Goubran Prof. Dr. Faten Moftah Prof. Dr. Magdy El-Ekiaby

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ENTRANCE TO HALL

AUDIENCE

NETWORKING

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5- Postgraduate Library The Department upgraded its postgraduate library books with the latest books in Hematology, Immunology, Microbiology, Genetics, Chemistry in addition to a range of books concerned with e-Learning, Presentation skills, Research methodology & Quality Assurance. The new books include:

Hematology 1. Hemato-pathology atlas (2009) 2. Clinical Laboratory Haematology(2009) 3. Haematology Clinical cases :Q&A (2009)

Chemistry 1. Clinical Chemistry (2010) 2. Clinical Chemistry (2010) 3. Clinical Biochemistry Metabolic and clinical aspects (2008) 4. Endocrine & Diabetes Clinical cases: Q&A (2009) 5. Q&A in Biochemistry (2010) 6. Drug assay (2010)

Transfusion Medicine 1. Transfusion Medicine & haemostasis(2009) 2. Practical Transfusion Medicine (2009)

Immunology 1. Cellular & Molecular Immunology (2010) 2. Cell biology & genetics (2008) 3. Q&A in Immunology & Microbiology(2010)

Molecular 1. Genetics: Analysis& Principles(2008) 2. Advanced Genetic analysis (2009)

Microbiology 1. Microbiology (2010) 2. Medical Mycology (2009) 3. Case files in Microbiology (2009) 4. Q&A in Immunology & Microbiology(2010)

Miscellaneous 1. Manual of Laboratory diagnostics (2008) 2. Phlebotomy (2009)

New era books

1. Management (2008)

2. Medical Ethics (2010)

3. Medical Quality management (2008)

Educational books (new)

1. Curriculum Leadership (2010)

2. Challenging e-learning in the University (2009)

3. Educational Research in Higher Education (2010)

4. Learning and Teaching in Higher Education (2009)

5. Presentation skills the Complete Handbook (2008)

6- Website redesign & updating: The website for the Clinical & Chemical expanded, updated, and published on the internet at:

Home About us Laboratory Services

Please contact us for additional information about our Department.

Prof. Dr. Ahmed El-Saifi,

MD Chair, Department of Clinical and Chemical Pathology

Contact the Chair's Office

2010 Annual Progress Report

2009 Annual Progress

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Website redesign & updating:

Clinical & Chemical Pathology Department has been redesigned,published on the internet at: http://www.clinchemcairo.org

Home About us Laboratory Services Projects Teaching &Training Faculty Events

contact us for additional information about our Department.

Saifi,

MD Chair, Department of Clinical and Chemical Pathology

Contact the Chair's Office

2010 Annual Progress Report

2009 Annual Progress Report

has been redesigned, http://www.clinchemcairo.org

Faculty Events Contact us