Alzheimer’s disease and treatment

Eman youssif

Medical research institute2013

The content:*structure of the brain

*risk factors

*mechanism of Alzheimer’s disease

*symptoms

*treatment

Hearing Words Speaking Words Seeing Words Thinking

structure

Hippocampus: where short-term memories are converted to long-term memories

Continue introduction

Proteins present normally in the brain

Risk factors

1-genetic factor

2 -environmental factor

3 -age

4-life style

medication

smoking

Sleep deprivation

Depression and stress

Nutritional deficiency

Mechanism of Alzheimer’s disease

video

?Inside the Brain Unraveling the Mystery of Alzheimer's Disease [HQ]?þ.webm

Accumulation of beta amyloid

TAU protein

Change of the brain

Affected regions begin to shrink as nerve cells die .

Symptoms of Alzheimer’s disease

Stage 1 (Mild) 2 to 4 years

depression

Less energetic Getting lostRepetitive

questions and conversations

Losing things or misplacing them in

odd places

Noticeable changes in

personality or mood

Stage 2

Stage 2 (Moderate): 2 to 10 years

Forget recent events and their personal history

More disoriented and disconnected

from reality

Speech problems arise and

understanding

Reading and writing are more

difficult

Stage 3

Stage 3 (Severe) : 1 to 3 years during final stage

lose the ability to feed themselves, speak,

recognize people and control bodily

functions.

Their memory worsens and may become

almost non-existent. They will sleep often.

Stage 3 =memory loss

Treatment for stage 1Stay calm and be understanding.

Be patient and flexible. Don’t argue or try to convince.

Acknowledge requests and respond to them

Treatment for stage 1

Music therapy

In Alzheimer disruption of wavesso music can alter this disruption

So the result change the moodtreatment the first stage of Alzheimer

Treatment for stage 2Color therapy

drugs

Donepezil ,rivastigmine and galantamine

Increase communication between the nerve cells

Temporarily improve or stabilize the symptoms of Alzheimer’s disease

Finally advise to you

Advise to you

references

Books:

1-Strategies for creating better care environmentBib Alex2-the encyclopedia of ALZ.. Disease –bib Alex3-designing for Alzheimer’s disease-bib Alex

web site:http://www.alz.org/aaic/overview.asp?gclid=CLyHlciwir0CFeFZ2wodAxUASAhttp://www.alzheimers.org.uk/site/scripts/documents_info.php?documentID=147http://www.mayoclinic.org/diseases-conditions/alzheimers-disease/basics/causes/con-20023871http://www.nia.nih.gov/alzheimers/publication/alzheimers-disease-genetics-fact-sheethttp://www.nature.com/nrn/posters/ad/index.htmlhttp://www.ncbi.nlm.nih.gov/pubmed/10653281http://www.plosone.org/article/info:doi/10.1371/journal.pone.0013812http://med.stanford.edu/news_releases/2007/july/music.htmlhttp://www.health.harvard.edu/newsweek/Preventing_memory_loss.htm

Lectures::

Neurology lec. By prof .dr .Mohamed B. Abou – Donia –December 2013Apoptosis course –medical research institute

Photo reference:

http://farm6.staticflickr.com/5286/5247137377_bb8a214e5f.jpg