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Dra. Pamela Jaramillo Ciencia de los Alimentos Prometeo-Senescyt Junio, 2013 Aplicación de la biotecnología en la industria alimentaria
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Dra Pamela Jaramillo Ciencia de los Alimentos Prometeo-Senescyt Junio 2013

Aplicacioacuten de la biotecnologiacutea en la industria alimentaria

Biotechnology use of biological processes and organisms for medical industrial or manuf proposes

Medical biotechnology

Plant biotechnology

Agricultural biotechnology

Industrial biotechnology

Microbial biotechnology

Enzyme biotechnology

Food biotechnology

Enzymes

Industry amp Research

Antimicrobials

Cleaning agents

ELISA

Functional properties

Amylase

Lactase

Protease

Lipase

Cellulase

Application of food biotechnology

Microorganisms

Ingredients

Vitamins

Amino acids

Citric lactic acid

Fermented products

Cheese

Yogurt

Fermented milks

Meat products

Beer amp wine

Application of food biotechnology

Functional food components

Fatty acids [CLA Omegas]

Carotenoids

Phytosterols

Bioactive peptides

Bioactive CHOrsquos

Essential minerals

Antioxidants

Enzymes ndash cleaning agents

The protease enzyme in Tergazyme is Bacillus licheniformis subtilisin carlsberg and is used for the cleaning of dairy equipment laboratory ware reverse osmosis and ultrafiltration membranes and units

Enzymes ndash cleaning agents

httpwwwphschoolcomsciencebiology_placelabbenchlab2conceptshtml

Catalase is used for the removal of H2O2 which is used as both a bleaching agent and an antimicrobial

httpwwwinlgovresearchultrastable-catalase-enzyme

Enzymes ndash antimicrobials

httpwwwnaturecomsrep2013130402srep01584fullsrep01584html

Ply500 is an isolated cell lytic enzyme with peptidase activity against certain L monocytogenes serotypes

Phages on the surface of an Escherichia coli cell Source Eye of ScienceScience

Enzymes ndash ELISA

ldquoAntigens from the sample are attached to a surface Then a further specific antibody is applied over the surface so it can bind to the antigen This antibody is linked to an enzyme and in the final step a substance containing the enzymes substrate is added The subsequent reaction produces a detectable signal most commonly a color change in the substraterdquo

httpthefutureofthingscomarticles37biopen-senses-biothreatshtml

Enzymes ndash for food processing

httpwwwnovasepcombiomoleculesfood-ingredientsApplicationssugar-and-sweeteners-productionasp

Amylase

ldquoAmylases in breadmaking break down complex sugars such as starch (found in flour) into simple sugars Yeast then feeds on these simple sugars and converts it into the waste products of alcohol and CO2 This imparts flavour and causes the bread to riserdquo

Amylase

Enzymes ndash for food processing

In traditional beer brewing malted barley is mixed with hot water to create a mash which is held at a given temperature to allow the amylases in the malted grain to convert the barleys starch into sugars Different temperatures optimize the activity of alpha or beta amylase resulting in different mixtures of fermentable and unfermentable sugars

Enzymes ndash for food processing

Enzymes ndash for food processing

Lactase

ldquoLactase produced commercially can be extracted both from yeasts such as Kluyveromyces fragilis and Kluyveromyces lactis and from fungi such as Aspergillus niger and Aspergillus oryzae Its primary commercial use is to break down lactose in milk to make it suitable for people with lactose intolerancerdquo wwwwikipediaorg

Enzymes ndash for food processing Protease

Calf rennet

Vegetable rennet Cynara cardunculus

Fermentation-produced chymosin Aspergillus niger var awamori GM

Enzymes ndash for food processing Protease

Papain

Meat is sprinkled with the powder and the enzymes help to break down the meat fibers

httpwwwenzymedevelopmentcomapplicationstenderizer

Use of Mucor miehei Lipase to Improve Functional Properties of Yolk-Contaminated Egg Whites Laura N Macherey Frank D Conforti William Eigel III Sean F OrsquoKeefe Journal of Food Science Volume 76 Issue 4 pages C651ndashC655 May 2011

Enzymes ndash for food processing

Lipase

Microorganisms ndash ingredients production

ldquoCorynebacterium glutamicum was discovered in the 1950s in Japan as natural producer of glutamic acid It is now produced by direct fermentation used for industrial production of amino acids which are used as flavour enhancers in foodrdquo

Glutamic acid amp Lysine

httpbacmapwishartlabcomorganisms485

Microorganisms ndash ingredients production

Citric acid

ldquoCultures of A niger are fed on a sucrose or glucose-containing medium to produce citric acid The source of sugar is corn steep liquor molasses hydrolyzed corn starch or other inexpensive sugary solutionsrdquo

httpgenomejgi-psforgAspni5Aspni5homehtml

Microorganisms ndash ingredients production

Bacillus subtilis has been genetically modified to both increase the bacterias production of riboflavin and to introduce an antibiotic (ampicillin) resistance marker wwwwikipediaorg

Riboflavin (Vitamin B2)

httpwwwocrawdogcomcat-chickenhtm

Colored scanning electron micrographs of representative cheese starter (A-C) and nonstarter (D-F) lactic acid bacteria (LAB) Lactobacillus helveticus (A) Lb delbrueckii subsp bulgaricus (B) Lactococcus lactis (C) Lb casei (D) Pediococcus pentosaceus (E) and Lb brevis (F)

Cheese

Microorganisms ndash fermented products

Microorganisms ndash fermented products

McSweeney P(2004) Biochemistry of cheese ripening Vol 57 (2-3) Int J Dairy Technol

Cheese_ Emmental

Microorganisms ndash fermented products

ldquoIn the late stage of cheese production P freudenreichii consumes the lactic acid excreted by the other bacteria and releases carbon dioxide gas which slowly forms the bubbles that make holesrdquo wwwwikipediaorg

Streptococcus thermophilus Lactobacillus debrueckii helveticus and Propionibacterium freudenreichii

Cheese_ Gouda

Microorganisms ndash fermented products

Lactococcus lactis ssp cremoris lactis Leuconostoc mesenteroides ssp cremoris

Leuconostoc mesenteroides ssp cremoris are starter cultures used for flavor and aroma development through the production of diacetyl from citrate

Roquefort

Microorganisms ndash fermented products

Camembert

ldquoPenicillium roqueforti and Penicillium caseicolum possess very potent proteolytic systems The molds secrete acid and neutral metalloproteinases and several aminopeptidases and carboxypeptidases The mycelia also contain intracellular proteinases and peptidases that are probably released when the mould dies and lysesrdquo

Microorganisms ndash fermented products

Fermented milks

Microorganisms ndash fermented products

Fermented milks

ldquoKefir grains are a combination of bacteria and yeasts in a matrix of proteins lipids and sugars and this symbiotic matrix forms grains that resemble cauliflower For this reason a complex and highly variable community of lactic acid bacteria and yeasts can be found in these grainsrdquo wwwwikipediaorg

Genus Lactobacillus Leuconostoc Pediococcus Streptococcus Bifidobacerium

Microorganisms ndash fermented products Fermented meats

Hutkins Robert W Microbiology and Technology of Fermented Foods

Pediococcus pentosaceus

httpbiowebusueduemlabcurrent20newshtml

Microorganisms ndash fermented products

Meat cultures

Lactobacillus sakei 10000-times magnified (Bild Joumlrg Groth Blessing Biotech GmbH)

Lactobacillus curvatus Lactobacillus plantarum Lactobacillus pentosus Streptococcus carnosus Micrococcus varians

httpwwwwzwtumdeindexphpid=185ampL=1amptx_ttnews5Btt_news5D=280

Microorganisms ndash fermented products

Meat cultures

httpwwwchr-hansencomproductsproduct-areasmeat-cultureshtml

Microorganisms ndash fermented products

Salami

ldquoPenicillium nalgiovense P chrysogenum and P camenberti used as starters The mold is desired as it imparts flavor helps the drying process prevents spoilage (mainly preventing growth of other mycotoxin-producing moulds during the curing process) and give a typical white color on the surfacerdquo

Microorganisms ndash fermented products

Wine amp Beer

Microorganisms ndash fermented products

Wine amp Beer

ldquoDuring fermentation the yeast converts the sugar in the wort to alcohol and carbon dioxide in addition to small amounts of glycerol and acetic acidrdquo

Yeast of the species Saccharomyces cerevisiae

httpenwikipediaorgwikiYeast

Microorganisms ndash other fermented products

httpwwwpsmicrographscoukrhizopus-mould--rhizopus-oligosporus-science-image80012871

Tempeh

Tempeh is manufactured from soaked boiled and dired soybeans that are inoculated with mold spores of species of Rhizopus (R stolonifer R oryzae R oigosporus or R arrhizus) The mash is packed or rolled in banana leaves and then incubated until there is good growth of mycelium but little sporulation Machve KK Fermentation Technology 2009

Functional food components

Critical Reviews in Food Science and Nutrition Structural Design Principles for Delivery of Bioactive Components in Nutraceuticals and Functional Foods 2011 McClements J Andrew E Yeonhwa D amp Weiss J

BioBest Omega 3 probiotic yogurt is a source of omega-3 PUFA that are considered an important part of a healthy diet It also contains over 1 billion active probiotic cultures Lactobacillus acidophilus NCFM Bifidobacterium lactis Bi-07 per serving that contribute to healthy digestive tract flora httpwwwastrocaproductsbiobest_omega_3_12x100g_multipackUbJJb_nVA8s

Functional food components ndash Omega 3

Inhibition of β-carotene degradation in oil-in-water nanoemulsions Influence of oil-soluble and water-soluble antioxidants Cheng Qian Eric Andrew Decker Hang Xiao David Julian McClements Volume 135 Issue 3 1 December 2012 Pages 1036ndash1043

Functional food components ndash Carotenoids

β-carotene enriched oil-in-water nanoemulsions stabilized by different emulsifiers with either no antioxidants (control) or antioxidants (80 μM EDTA + 10000 ppm vitamin E acetate)

Functional food components ndash Polyphenols

Pomegranate Phenolics from the Peels Arils and Flowers Are Antiatherogenic Studies in Vivo in Atherosclerotic Apolipoprotein E-Deficient (E0) Mice and in Vitro in Cultured Macrophages and Lipoproteins J Agric Food Chem 2008 56 (3) pp 1148ndash1157

Pomegranate phenolics and mainly oligomers punicalagin punicalin and gallic and ellagic acids are major contributors to the beneficial effects of pomegranate juice

Functional food components ndash Antioxidant activity

J Med Food 2012 Nov15(11)968-73 doi 101089jmf20122282 Epub 2012 Oct 12 Prickly pear cactus (Opuntia ficus indica var saboten) protects against stress-induced acute gastric lesions in rats (maltodextrin y betanin)

httpcancerpreventionresearchaacrjournalsorgcontentearly200906191940-6207CAPR-08-0167abstract

Tea Polyphenols Decrease Serum Levels of Prostate-Specific Antigen Hepatocyte Growth Factor and Vascular Endothelial Growth Factor in Prostate Cancer Patients and Inhibit Production of Hepatocyte Growth Factor and Vascular Endothelial Growth Factor In vitro 2008 Jerry McLarty Rebecca LH Bigelow Mylinh Smith Don Elmajian Murali Ankem James A Cardelli

Functional food components ndash Polyphenols

ldquoNano-sized self assembled structured liquids = nanodrops Liquid carriers that pass through the digestive system effectively without sinking or breaking up to the absorption site These nanodrops carry the phytosterols to the large micelles that the body produces from the bile acid where they compete with cholesterol for entry into the micelle The phytosterols enter the micelle thereby inhibiting transportation of cholesterol from the digestive system into the bloodstreamrdquo Shemen Industries

Functional food components ndash Phytosterols

Goacutemez-Guilleacuten M C B Gimeacutenez et al (2011) Functional and bioactive properties of collagen and gelatin from alternative sources A review Food Hydrocolloids 25(8) 1813-1827

Functional food components ndash Bioactive peptides

httpwwwnuritascomscreening-mining-food-for-bioactive-peptides

Health and nutrition benefits associated with Fibregum its fermentation in the large bowel increases levels of beneficial bacteria which stimulates the production of short-chain fatty acids (SCFAs) that have such properties as lowering serum cholesterol it is a strong prebiotic helping to balance the intestinal microbial ecosystem in the distal colon

Functional food components ndash Prebiotic fiber

httpwwwnexiracomFibregumE284A2-healthy-prebiotic-fiber_6html

Senegalia senegal (acacia)

Functional food components ndash Essential minerals (Fe Zn Ca Se)

httpwwwfdagovFoodGuidanceRegulationGuidanceDocumentsRegulatoryInformationLabelingNutritionucm152626htm

Pseudocereals are considered an important energy source due to their starch content they also provide good quality protein dietary fibre and lipids rich in unsaturated fats They contain adequate levels of minerals and vitamins and significant amounts of other bioactive components such as saponins phytosterols squalene fagopyritols and polyphenols

Functional food components ndash micronutrients

httpquinuapewp-contentuploads201302antiox-Gallagherpdf

Seven-step process would ensure that functional foods are safe and effective with health claims that are accurate and regulatory oversight that is science based and efficient

Functional foods

FERGUS CLYDESDALE 2004 Functional Foods Opportunities amp Challenges Food Technology December 2004 Volume 58 No12

httpwwwgooglecompatentsUS20100196569

httpwwwgooglecompatentsWO2006048158A1cl=en

httpswwwgooglecompatentsUS6428824pg=PA2ampdq=Lepidium+peruvianumamphl=enampsa=Xampei=KxK2UanpKvOu4AOehICgDwampved=0CDoQ6AEwATgK

httpswwwgooglecompatentsUS7005148pg=PA3ampdq=vaccinium+corymbosumamphl=enampsa=Xampei=-xK2UZ7vF_a64AO0soG4Cgampsqi=2amppjf=1ampved=0CGwQ6AEwCA

httpswwwgooglecompatentsWO2001045648A2cl=enampdq=vaccinium+corymbosumamphl=enampsa=Xampei=9BO2Uc_5A9Sz4AOrsIEIampved=0CDQQ6AEwAA

Potential for future researchhellip

Top health issues consumers are concerned about preventing From NMI(2005)

A ELIZABETH SLOAN 2006 Top 10 Functional Food Trends Food Technology Volume 60 No 4

Biotechnology use of biological processes and organisms for medical industrial or manuf proposes

Medical biotechnology

Plant biotechnology

Agricultural biotechnology

Industrial biotechnology

Microbial biotechnology

Enzyme biotechnology

Food biotechnology

Enzymes

Industry amp Research

Antimicrobials

Cleaning agents

ELISA

Functional properties

Amylase

Lactase

Protease

Lipase

Cellulase

Application of food biotechnology

Microorganisms

Ingredients

Vitamins

Amino acids

Citric lactic acid

Fermented products

Cheese

Yogurt

Fermented milks

Meat products

Beer amp wine

Application of food biotechnology

Functional food components

Fatty acids [CLA Omegas]

Carotenoids

Phytosterols

Bioactive peptides

Bioactive CHOrsquos

Essential minerals

Antioxidants

Enzymes ndash cleaning agents

The protease enzyme in Tergazyme is Bacillus licheniformis subtilisin carlsberg and is used for the cleaning of dairy equipment laboratory ware reverse osmosis and ultrafiltration membranes and units

Enzymes ndash cleaning agents

httpwwwphschoolcomsciencebiology_placelabbenchlab2conceptshtml

Catalase is used for the removal of H2O2 which is used as both a bleaching agent and an antimicrobial

httpwwwinlgovresearchultrastable-catalase-enzyme

Enzymes ndash antimicrobials

httpwwwnaturecomsrep2013130402srep01584fullsrep01584html

Ply500 is an isolated cell lytic enzyme with peptidase activity against certain L monocytogenes serotypes

Phages on the surface of an Escherichia coli cell Source Eye of ScienceScience

Enzymes ndash ELISA

ldquoAntigens from the sample are attached to a surface Then a further specific antibody is applied over the surface so it can bind to the antigen This antibody is linked to an enzyme and in the final step a substance containing the enzymes substrate is added The subsequent reaction produces a detectable signal most commonly a color change in the substraterdquo

httpthefutureofthingscomarticles37biopen-senses-biothreatshtml

Enzymes ndash for food processing

httpwwwnovasepcombiomoleculesfood-ingredientsApplicationssugar-and-sweeteners-productionasp

Amylase

ldquoAmylases in breadmaking break down complex sugars such as starch (found in flour) into simple sugars Yeast then feeds on these simple sugars and converts it into the waste products of alcohol and CO2 This imparts flavour and causes the bread to riserdquo

Amylase

Enzymes ndash for food processing

In traditional beer brewing malted barley is mixed with hot water to create a mash which is held at a given temperature to allow the amylases in the malted grain to convert the barleys starch into sugars Different temperatures optimize the activity of alpha or beta amylase resulting in different mixtures of fermentable and unfermentable sugars

Enzymes ndash for food processing

Enzymes ndash for food processing

Lactase

ldquoLactase produced commercially can be extracted both from yeasts such as Kluyveromyces fragilis and Kluyveromyces lactis and from fungi such as Aspergillus niger and Aspergillus oryzae Its primary commercial use is to break down lactose in milk to make it suitable for people with lactose intolerancerdquo wwwwikipediaorg

Enzymes ndash for food processing Protease

Calf rennet

Vegetable rennet Cynara cardunculus

Fermentation-produced chymosin Aspergillus niger var awamori GM

Enzymes ndash for food processing Protease

Papain

Meat is sprinkled with the powder and the enzymes help to break down the meat fibers

httpwwwenzymedevelopmentcomapplicationstenderizer

Use of Mucor miehei Lipase to Improve Functional Properties of Yolk-Contaminated Egg Whites Laura N Macherey Frank D Conforti William Eigel III Sean F OrsquoKeefe Journal of Food Science Volume 76 Issue 4 pages C651ndashC655 May 2011

Enzymes ndash for food processing

Lipase

Microorganisms ndash ingredients production

ldquoCorynebacterium glutamicum was discovered in the 1950s in Japan as natural producer of glutamic acid It is now produced by direct fermentation used for industrial production of amino acids which are used as flavour enhancers in foodrdquo

Glutamic acid amp Lysine

httpbacmapwishartlabcomorganisms485

Microorganisms ndash ingredients production

Citric acid

ldquoCultures of A niger are fed on a sucrose or glucose-containing medium to produce citric acid The source of sugar is corn steep liquor molasses hydrolyzed corn starch or other inexpensive sugary solutionsrdquo

httpgenomejgi-psforgAspni5Aspni5homehtml

Microorganisms ndash ingredients production

Bacillus subtilis has been genetically modified to both increase the bacterias production of riboflavin and to introduce an antibiotic (ampicillin) resistance marker wwwwikipediaorg

Riboflavin (Vitamin B2)

httpwwwocrawdogcomcat-chickenhtm

Colored scanning electron micrographs of representative cheese starter (A-C) and nonstarter (D-F) lactic acid bacteria (LAB) Lactobacillus helveticus (A) Lb delbrueckii subsp bulgaricus (B) Lactococcus lactis (C) Lb casei (D) Pediococcus pentosaceus (E) and Lb brevis (F)

Cheese

Microorganisms ndash fermented products

Microorganisms ndash fermented products

McSweeney P(2004) Biochemistry of cheese ripening Vol 57 (2-3) Int J Dairy Technol

Cheese_ Emmental

Microorganisms ndash fermented products

ldquoIn the late stage of cheese production P freudenreichii consumes the lactic acid excreted by the other bacteria and releases carbon dioxide gas which slowly forms the bubbles that make holesrdquo wwwwikipediaorg

Streptococcus thermophilus Lactobacillus debrueckii helveticus and Propionibacterium freudenreichii

Cheese_ Gouda

Microorganisms ndash fermented products

Lactococcus lactis ssp cremoris lactis Leuconostoc mesenteroides ssp cremoris

Leuconostoc mesenteroides ssp cremoris are starter cultures used for flavor and aroma development through the production of diacetyl from citrate

Roquefort

Microorganisms ndash fermented products

Camembert

ldquoPenicillium roqueforti and Penicillium caseicolum possess very potent proteolytic systems The molds secrete acid and neutral metalloproteinases and several aminopeptidases and carboxypeptidases The mycelia also contain intracellular proteinases and peptidases that are probably released when the mould dies and lysesrdquo

Microorganisms ndash fermented products

Fermented milks

Microorganisms ndash fermented products

Fermented milks

ldquoKefir grains are a combination of bacteria and yeasts in a matrix of proteins lipids and sugars and this symbiotic matrix forms grains that resemble cauliflower For this reason a complex and highly variable community of lactic acid bacteria and yeasts can be found in these grainsrdquo wwwwikipediaorg

Genus Lactobacillus Leuconostoc Pediococcus Streptococcus Bifidobacerium

Microorganisms ndash fermented products Fermented meats

Hutkins Robert W Microbiology and Technology of Fermented Foods

Pediococcus pentosaceus

httpbiowebusueduemlabcurrent20newshtml

Microorganisms ndash fermented products

Meat cultures

Lactobacillus sakei 10000-times magnified (Bild Joumlrg Groth Blessing Biotech GmbH)

Lactobacillus curvatus Lactobacillus plantarum Lactobacillus pentosus Streptococcus carnosus Micrococcus varians

httpwwwwzwtumdeindexphpid=185ampL=1amptx_ttnews5Btt_news5D=280

Microorganisms ndash fermented products

Meat cultures

httpwwwchr-hansencomproductsproduct-areasmeat-cultureshtml

Microorganisms ndash fermented products

Salami

ldquoPenicillium nalgiovense P chrysogenum and P camenberti used as starters The mold is desired as it imparts flavor helps the drying process prevents spoilage (mainly preventing growth of other mycotoxin-producing moulds during the curing process) and give a typical white color on the surfacerdquo

Microorganisms ndash fermented products

Wine amp Beer

Microorganisms ndash fermented products

Wine amp Beer

ldquoDuring fermentation the yeast converts the sugar in the wort to alcohol and carbon dioxide in addition to small amounts of glycerol and acetic acidrdquo

Yeast of the species Saccharomyces cerevisiae

httpenwikipediaorgwikiYeast

Microorganisms ndash other fermented products

httpwwwpsmicrographscoukrhizopus-mould--rhizopus-oligosporus-science-image80012871

Tempeh

Tempeh is manufactured from soaked boiled and dired soybeans that are inoculated with mold spores of species of Rhizopus (R stolonifer R oryzae R oigosporus or R arrhizus) The mash is packed or rolled in banana leaves and then incubated until there is good growth of mycelium but little sporulation Machve KK Fermentation Technology 2009

Functional food components

Critical Reviews in Food Science and Nutrition Structural Design Principles for Delivery of Bioactive Components in Nutraceuticals and Functional Foods 2011 McClements J Andrew E Yeonhwa D amp Weiss J

BioBest Omega 3 probiotic yogurt is a source of omega-3 PUFA that are considered an important part of a healthy diet It also contains over 1 billion active probiotic cultures Lactobacillus acidophilus NCFM Bifidobacterium lactis Bi-07 per serving that contribute to healthy digestive tract flora httpwwwastrocaproductsbiobest_omega_3_12x100g_multipackUbJJb_nVA8s

Functional food components ndash Omega 3

Inhibition of β-carotene degradation in oil-in-water nanoemulsions Influence of oil-soluble and water-soluble antioxidants Cheng Qian Eric Andrew Decker Hang Xiao David Julian McClements Volume 135 Issue 3 1 December 2012 Pages 1036ndash1043

Functional food components ndash Carotenoids

β-carotene enriched oil-in-water nanoemulsions stabilized by different emulsifiers with either no antioxidants (control) or antioxidants (80 μM EDTA + 10000 ppm vitamin E acetate)

Functional food components ndash Polyphenols

Pomegranate Phenolics from the Peels Arils and Flowers Are Antiatherogenic Studies in Vivo in Atherosclerotic Apolipoprotein E-Deficient (E0) Mice and in Vitro in Cultured Macrophages and Lipoproteins J Agric Food Chem 2008 56 (3) pp 1148ndash1157

Pomegranate phenolics and mainly oligomers punicalagin punicalin and gallic and ellagic acids are major contributors to the beneficial effects of pomegranate juice

Functional food components ndash Antioxidant activity

J Med Food 2012 Nov15(11)968-73 doi 101089jmf20122282 Epub 2012 Oct 12 Prickly pear cactus (Opuntia ficus indica var saboten) protects against stress-induced acute gastric lesions in rats (maltodextrin y betanin)

httpcancerpreventionresearchaacrjournalsorgcontentearly200906191940-6207CAPR-08-0167abstract

Tea Polyphenols Decrease Serum Levels of Prostate-Specific Antigen Hepatocyte Growth Factor and Vascular Endothelial Growth Factor in Prostate Cancer Patients and Inhibit Production of Hepatocyte Growth Factor and Vascular Endothelial Growth Factor In vitro 2008 Jerry McLarty Rebecca LH Bigelow Mylinh Smith Don Elmajian Murali Ankem James A Cardelli

Functional food components ndash Polyphenols

ldquoNano-sized self assembled structured liquids = nanodrops Liquid carriers that pass through the digestive system effectively without sinking or breaking up to the absorption site These nanodrops carry the phytosterols to the large micelles that the body produces from the bile acid where they compete with cholesterol for entry into the micelle The phytosterols enter the micelle thereby inhibiting transportation of cholesterol from the digestive system into the bloodstreamrdquo Shemen Industries

Functional food components ndash Phytosterols

Goacutemez-Guilleacuten M C B Gimeacutenez et al (2011) Functional and bioactive properties of collagen and gelatin from alternative sources A review Food Hydrocolloids 25(8) 1813-1827

Functional food components ndash Bioactive peptides

httpwwwnuritascomscreening-mining-food-for-bioactive-peptides

Health and nutrition benefits associated with Fibregum its fermentation in the large bowel increases levels of beneficial bacteria which stimulates the production of short-chain fatty acids (SCFAs) that have such properties as lowering serum cholesterol it is a strong prebiotic helping to balance the intestinal microbial ecosystem in the distal colon

Functional food components ndash Prebiotic fiber

httpwwwnexiracomFibregumE284A2-healthy-prebiotic-fiber_6html

Senegalia senegal (acacia)

Functional food components ndash Essential minerals (Fe Zn Ca Se)

httpwwwfdagovFoodGuidanceRegulationGuidanceDocumentsRegulatoryInformationLabelingNutritionucm152626htm

Pseudocereals are considered an important energy source due to their starch content they also provide good quality protein dietary fibre and lipids rich in unsaturated fats They contain adequate levels of minerals and vitamins and significant amounts of other bioactive components such as saponins phytosterols squalene fagopyritols and polyphenols

Functional food components ndash micronutrients

httpquinuapewp-contentuploads201302antiox-Gallagherpdf

Seven-step process would ensure that functional foods are safe and effective with health claims that are accurate and regulatory oversight that is science based and efficient

Functional foods

FERGUS CLYDESDALE 2004 Functional Foods Opportunities amp Challenges Food Technology December 2004 Volume 58 No12

httpwwwgooglecompatentsUS20100196569

httpwwwgooglecompatentsWO2006048158A1cl=en

httpswwwgooglecompatentsUS6428824pg=PA2ampdq=Lepidium+peruvianumamphl=enampsa=Xampei=KxK2UanpKvOu4AOehICgDwampved=0CDoQ6AEwATgK

httpswwwgooglecompatentsUS7005148pg=PA3ampdq=vaccinium+corymbosumamphl=enampsa=Xampei=-xK2UZ7vF_a64AO0soG4Cgampsqi=2amppjf=1ampved=0CGwQ6AEwCA

httpswwwgooglecompatentsWO2001045648A2cl=enampdq=vaccinium+corymbosumamphl=enampsa=Xampei=9BO2Uc_5A9Sz4AOrsIEIampved=0CDQQ6AEwAA

Potential for future researchhellip

Top health issues consumers are concerned about preventing From NMI(2005)

A ELIZABETH SLOAN 2006 Top 10 Functional Food Trends Food Technology Volume 60 No 4

Enzymes

Industry amp Research

Antimicrobials

Cleaning agents

ELISA

Functional properties

Amylase

Lactase

Protease

Lipase

Cellulase

Application of food biotechnology

Microorganisms

Ingredients

Vitamins

Amino acids

Citric lactic acid

Fermented products

Cheese

Yogurt

Fermented milks

Meat products

Beer amp wine

Application of food biotechnology

Functional food components

Fatty acids [CLA Omegas]

Carotenoids

Phytosterols

Bioactive peptides

Bioactive CHOrsquos

Essential minerals

Antioxidants

Enzymes ndash cleaning agents

The protease enzyme in Tergazyme is Bacillus licheniformis subtilisin carlsberg and is used for the cleaning of dairy equipment laboratory ware reverse osmosis and ultrafiltration membranes and units

Enzymes ndash cleaning agents

httpwwwphschoolcomsciencebiology_placelabbenchlab2conceptshtml

Catalase is used for the removal of H2O2 which is used as both a bleaching agent and an antimicrobial

httpwwwinlgovresearchultrastable-catalase-enzyme

Enzymes ndash antimicrobials

httpwwwnaturecomsrep2013130402srep01584fullsrep01584html

Ply500 is an isolated cell lytic enzyme with peptidase activity against certain L monocytogenes serotypes

Phages on the surface of an Escherichia coli cell Source Eye of ScienceScience

Enzymes ndash ELISA

ldquoAntigens from the sample are attached to a surface Then a further specific antibody is applied over the surface so it can bind to the antigen This antibody is linked to an enzyme and in the final step a substance containing the enzymes substrate is added The subsequent reaction produces a detectable signal most commonly a color change in the substraterdquo

httpthefutureofthingscomarticles37biopen-senses-biothreatshtml

Enzymes ndash for food processing

httpwwwnovasepcombiomoleculesfood-ingredientsApplicationssugar-and-sweeteners-productionasp

Amylase

ldquoAmylases in breadmaking break down complex sugars such as starch (found in flour) into simple sugars Yeast then feeds on these simple sugars and converts it into the waste products of alcohol and CO2 This imparts flavour and causes the bread to riserdquo

Amylase

Enzymes ndash for food processing

In traditional beer brewing malted barley is mixed with hot water to create a mash which is held at a given temperature to allow the amylases in the malted grain to convert the barleys starch into sugars Different temperatures optimize the activity of alpha or beta amylase resulting in different mixtures of fermentable and unfermentable sugars

Enzymes ndash for food processing

Enzymes ndash for food processing

Lactase

ldquoLactase produced commercially can be extracted both from yeasts such as Kluyveromyces fragilis and Kluyveromyces lactis and from fungi such as Aspergillus niger and Aspergillus oryzae Its primary commercial use is to break down lactose in milk to make it suitable for people with lactose intolerancerdquo wwwwikipediaorg

Enzymes ndash for food processing Protease

Calf rennet

Vegetable rennet Cynara cardunculus

Fermentation-produced chymosin Aspergillus niger var awamori GM

Enzymes ndash for food processing Protease

Papain

Meat is sprinkled with the powder and the enzymes help to break down the meat fibers

httpwwwenzymedevelopmentcomapplicationstenderizer

Use of Mucor miehei Lipase to Improve Functional Properties of Yolk-Contaminated Egg Whites Laura N Macherey Frank D Conforti William Eigel III Sean F OrsquoKeefe Journal of Food Science Volume 76 Issue 4 pages C651ndashC655 May 2011

Enzymes ndash for food processing

Lipase

Microorganisms ndash ingredients production

ldquoCorynebacterium glutamicum was discovered in the 1950s in Japan as natural producer of glutamic acid It is now produced by direct fermentation used for industrial production of amino acids which are used as flavour enhancers in foodrdquo

Glutamic acid amp Lysine

httpbacmapwishartlabcomorganisms485

Microorganisms ndash ingredients production

Citric acid

ldquoCultures of A niger are fed on a sucrose or glucose-containing medium to produce citric acid The source of sugar is corn steep liquor molasses hydrolyzed corn starch or other inexpensive sugary solutionsrdquo

httpgenomejgi-psforgAspni5Aspni5homehtml

Microorganisms ndash ingredients production

Bacillus subtilis has been genetically modified to both increase the bacterias production of riboflavin and to introduce an antibiotic (ampicillin) resistance marker wwwwikipediaorg

Riboflavin (Vitamin B2)

httpwwwocrawdogcomcat-chickenhtm

Colored scanning electron micrographs of representative cheese starter (A-C) and nonstarter (D-F) lactic acid bacteria (LAB) Lactobacillus helveticus (A) Lb delbrueckii subsp bulgaricus (B) Lactococcus lactis (C) Lb casei (D) Pediococcus pentosaceus (E) and Lb brevis (F)

Cheese

Microorganisms ndash fermented products

Microorganisms ndash fermented products

McSweeney P(2004) Biochemistry of cheese ripening Vol 57 (2-3) Int J Dairy Technol

Cheese_ Emmental

Microorganisms ndash fermented products

ldquoIn the late stage of cheese production P freudenreichii consumes the lactic acid excreted by the other bacteria and releases carbon dioxide gas which slowly forms the bubbles that make holesrdquo wwwwikipediaorg

Streptococcus thermophilus Lactobacillus debrueckii helveticus and Propionibacterium freudenreichii

Cheese_ Gouda

Microorganisms ndash fermented products

Lactococcus lactis ssp cremoris lactis Leuconostoc mesenteroides ssp cremoris

Leuconostoc mesenteroides ssp cremoris are starter cultures used for flavor and aroma development through the production of diacetyl from citrate

Roquefort

Microorganisms ndash fermented products

Camembert

ldquoPenicillium roqueforti and Penicillium caseicolum possess very potent proteolytic systems The molds secrete acid and neutral metalloproteinases and several aminopeptidases and carboxypeptidases The mycelia also contain intracellular proteinases and peptidases that are probably released when the mould dies and lysesrdquo

Microorganisms ndash fermented products

Fermented milks

Microorganisms ndash fermented products

Fermented milks

ldquoKefir grains are a combination of bacteria and yeasts in a matrix of proteins lipids and sugars and this symbiotic matrix forms grains that resemble cauliflower For this reason a complex and highly variable community of lactic acid bacteria and yeasts can be found in these grainsrdquo wwwwikipediaorg

Genus Lactobacillus Leuconostoc Pediococcus Streptococcus Bifidobacerium

Microorganisms ndash fermented products Fermented meats

Hutkins Robert W Microbiology and Technology of Fermented Foods

Pediococcus pentosaceus

httpbiowebusueduemlabcurrent20newshtml

Microorganisms ndash fermented products

Meat cultures

Lactobacillus sakei 10000-times magnified (Bild Joumlrg Groth Blessing Biotech GmbH)

Lactobacillus curvatus Lactobacillus plantarum Lactobacillus pentosus Streptococcus carnosus Micrococcus varians

httpwwwwzwtumdeindexphpid=185ampL=1amptx_ttnews5Btt_news5D=280

Microorganisms ndash fermented products

Meat cultures

httpwwwchr-hansencomproductsproduct-areasmeat-cultureshtml

Microorganisms ndash fermented products

Salami

ldquoPenicillium nalgiovense P chrysogenum and P camenberti used as starters The mold is desired as it imparts flavor helps the drying process prevents spoilage (mainly preventing growth of other mycotoxin-producing moulds during the curing process) and give a typical white color on the surfacerdquo

Microorganisms ndash fermented products

Wine amp Beer

Microorganisms ndash fermented products

Wine amp Beer

ldquoDuring fermentation the yeast converts the sugar in the wort to alcohol and carbon dioxide in addition to small amounts of glycerol and acetic acidrdquo

Yeast of the species Saccharomyces cerevisiae

httpenwikipediaorgwikiYeast

Microorganisms ndash other fermented products

httpwwwpsmicrographscoukrhizopus-mould--rhizopus-oligosporus-science-image80012871

Tempeh

Tempeh is manufactured from soaked boiled and dired soybeans that are inoculated with mold spores of species of Rhizopus (R stolonifer R oryzae R oigosporus or R arrhizus) The mash is packed or rolled in banana leaves and then incubated until there is good growth of mycelium but little sporulation Machve KK Fermentation Technology 2009

Functional food components

Critical Reviews in Food Science and Nutrition Structural Design Principles for Delivery of Bioactive Components in Nutraceuticals and Functional Foods 2011 McClements J Andrew E Yeonhwa D amp Weiss J

BioBest Omega 3 probiotic yogurt is a source of omega-3 PUFA that are considered an important part of a healthy diet It also contains over 1 billion active probiotic cultures Lactobacillus acidophilus NCFM Bifidobacterium lactis Bi-07 per serving that contribute to healthy digestive tract flora httpwwwastrocaproductsbiobest_omega_3_12x100g_multipackUbJJb_nVA8s

Functional food components ndash Omega 3

Inhibition of β-carotene degradation in oil-in-water nanoemulsions Influence of oil-soluble and water-soluble antioxidants Cheng Qian Eric Andrew Decker Hang Xiao David Julian McClements Volume 135 Issue 3 1 December 2012 Pages 1036ndash1043

Functional food components ndash Carotenoids

β-carotene enriched oil-in-water nanoemulsions stabilized by different emulsifiers with either no antioxidants (control) or antioxidants (80 μM EDTA + 10000 ppm vitamin E acetate)

Functional food components ndash Polyphenols

Pomegranate Phenolics from the Peels Arils and Flowers Are Antiatherogenic Studies in Vivo in Atherosclerotic Apolipoprotein E-Deficient (E0) Mice and in Vitro in Cultured Macrophages and Lipoproteins J Agric Food Chem 2008 56 (3) pp 1148ndash1157

Pomegranate phenolics and mainly oligomers punicalagin punicalin and gallic and ellagic acids are major contributors to the beneficial effects of pomegranate juice

Functional food components ndash Antioxidant activity

J Med Food 2012 Nov15(11)968-73 doi 101089jmf20122282 Epub 2012 Oct 12 Prickly pear cactus (Opuntia ficus indica var saboten) protects against stress-induced acute gastric lesions in rats (maltodextrin y betanin)

httpcancerpreventionresearchaacrjournalsorgcontentearly200906191940-6207CAPR-08-0167abstract

Tea Polyphenols Decrease Serum Levels of Prostate-Specific Antigen Hepatocyte Growth Factor and Vascular Endothelial Growth Factor in Prostate Cancer Patients and Inhibit Production of Hepatocyte Growth Factor and Vascular Endothelial Growth Factor In vitro 2008 Jerry McLarty Rebecca LH Bigelow Mylinh Smith Don Elmajian Murali Ankem James A Cardelli

Functional food components ndash Polyphenols

ldquoNano-sized self assembled structured liquids = nanodrops Liquid carriers that pass through the digestive system effectively without sinking or breaking up to the absorption site These nanodrops carry the phytosterols to the large micelles that the body produces from the bile acid where they compete with cholesterol for entry into the micelle The phytosterols enter the micelle thereby inhibiting transportation of cholesterol from the digestive system into the bloodstreamrdquo Shemen Industries

Functional food components ndash Phytosterols

Goacutemez-Guilleacuten M C B Gimeacutenez et al (2011) Functional and bioactive properties of collagen and gelatin from alternative sources A review Food Hydrocolloids 25(8) 1813-1827

Functional food components ndash Bioactive peptides

httpwwwnuritascomscreening-mining-food-for-bioactive-peptides

Health and nutrition benefits associated with Fibregum its fermentation in the large bowel increases levels of beneficial bacteria which stimulates the production of short-chain fatty acids (SCFAs) that have such properties as lowering serum cholesterol it is a strong prebiotic helping to balance the intestinal microbial ecosystem in the distal colon

Functional food components ndash Prebiotic fiber

httpwwwnexiracomFibregumE284A2-healthy-prebiotic-fiber_6html

Senegalia senegal (acacia)

Functional food components ndash Essential minerals (Fe Zn Ca Se)

httpwwwfdagovFoodGuidanceRegulationGuidanceDocumentsRegulatoryInformationLabelingNutritionucm152626htm

Pseudocereals are considered an important energy source due to their starch content they also provide good quality protein dietary fibre and lipids rich in unsaturated fats They contain adequate levels of minerals and vitamins and significant amounts of other bioactive components such as saponins phytosterols squalene fagopyritols and polyphenols

Functional food components ndash micronutrients

httpquinuapewp-contentuploads201302antiox-Gallagherpdf

Seven-step process would ensure that functional foods are safe and effective with health claims that are accurate and regulatory oversight that is science based and efficient

Functional foods

FERGUS CLYDESDALE 2004 Functional Foods Opportunities amp Challenges Food Technology December 2004 Volume 58 No12

httpwwwgooglecompatentsUS20100196569

httpwwwgooglecompatentsWO2006048158A1cl=en

httpswwwgooglecompatentsUS6428824pg=PA2ampdq=Lepidium+peruvianumamphl=enampsa=Xampei=KxK2UanpKvOu4AOehICgDwampved=0CDoQ6AEwATgK

httpswwwgooglecompatentsUS7005148pg=PA3ampdq=vaccinium+corymbosumamphl=enampsa=Xampei=-xK2UZ7vF_a64AO0soG4Cgampsqi=2amppjf=1ampved=0CGwQ6AEwCA

httpswwwgooglecompatentsWO2001045648A2cl=enampdq=vaccinium+corymbosumamphl=enampsa=Xampei=9BO2Uc_5A9Sz4AOrsIEIampved=0CDQQ6AEwAA

Potential for future researchhellip

Top health issues consumers are concerned about preventing From NMI(2005)

A ELIZABETH SLOAN 2006 Top 10 Functional Food Trends Food Technology Volume 60 No 4

Microorganisms

Ingredients

Vitamins

Amino acids

Citric lactic acid

Fermented products

Cheese

Yogurt

Fermented milks

Meat products

Beer amp wine

Application of food biotechnology

Functional food components

Fatty acids [CLA Omegas]

Carotenoids

Phytosterols

Bioactive peptides

Bioactive CHOrsquos

Essential minerals

Antioxidants

Enzymes ndash cleaning agents

The protease enzyme in Tergazyme is Bacillus licheniformis subtilisin carlsberg and is used for the cleaning of dairy equipment laboratory ware reverse osmosis and ultrafiltration membranes and units

Enzymes ndash cleaning agents

httpwwwphschoolcomsciencebiology_placelabbenchlab2conceptshtml

Catalase is used for the removal of H2O2 which is used as both a bleaching agent and an antimicrobial

httpwwwinlgovresearchultrastable-catalase-enzyme

Enzymes ndash antimicrobials

httpwwwnaturecomsrep2013130402srep01584fullsrep01584html

Ply500 is an isolated cell lytic enzyme with peptidase activity against certain L monocytogenes serotypes

Phages on the surface of an Escherichia coli cell Source Eye of ScienceScience

Enzymes ndash ELISA

ldquoAntigens from the sample are attached to a surface Then a further specific antibody is applied over the surface so it can bind to the antigen This antibody is linked to an enzyme and in the final step a substance containing the enzymes substrate is added The subsequent reaction produces a detectable signal most commonly a color change in the substraterdquo

httpthefutureofthingscomarticles37biopen-senses-biothreatshtml

Enzymes ndash for food processing

httpwwwnovasepcombiomoleculesfood-ingredientsApplicationssugar-and-sweeteners-productionasp

Amylase

ldquoAmylases in breadmaking break down complex sugars such as starch (found in flour) into simple sugars Yeast then feeds on these simple sugars and converts it into the waste products of alcohol and CO2 This imparts flavour and causes the bread to riserdquo

Amylase

Enzymes ndash for food processing

In traditional beer brewing malted barley is mixed with hot water to create a mash which is held at a given temperature to allow the amylases in the malted grain to convert the barleys starch into sugars Different temperatures optimize the activity of alpha or beta amylase resulting in different mixtures of fermentable and unfermentable sugars

Enzymes ndash for food processing

Enzymes ndash for food processing

Lactase

ldquoLactase produced commercially can be extracted both from yeasts such as Kluyveromyces fragilis and Kluyveromyces lactis and from fungi such as Aspergillus niger and Aspergillus oryzae Its primary commercial use is to break down lactose in milk to make it suitable for people with lactose intolerancerdquo wwwwikipediaorg

Enzymes ndash for food processing Protease

Calf rennet

Vegetable rennet Cynara cardunculus

Fermentation-produced chymosin Aspergillus niger var awamori GM

Enzymes ndash for food processing Protease

Papain

Meat is sprinkled with the powder and the enzymes help to break down the meat fibers

httpwwwenzymedevelopmentcomapplicationstenderizer

Use of Mucor miehei Lipase to Improve Functional Properties of Yolk-Contaminated Egg Whites Laura N Macherey Frank D Conforti William Eigel III Sean F OrsquoKeefe Journal of Food Science Volume 76 Issue 4 pages C651ndashC655 May 2011

Enzymes ndash for food processing

Lipase

Microorganisms ndash ingredients production

ldquoCorynebacterium glutamicum was discovered in the 1950s in Japan as natural producer of glutamic acid It is now produced by direct fermentation used for industrial production of amino acids which are used as flavour enhancers in foodrdquo

Glutamic acid amp Lysine

httpbacmapwishartlabcomorganisms485

Microorganisms ndash ingredients production

Citric acid

ldquoCultures of A niger are fed on a sucrose or glucose-containing medium to produce citric acid The source of sugar is corn steep liquor molasses hydrolyzed corn starch or other inexpensive sugary solutionsrdquo

httpgenomejgi-psforgAspni5Aspni5homehtml

Microorganisms ndash ingredients production

Bacillus subtilis has been genetically modified to both increase the bacterias production of riboflavin and to introduce an antibiotic (ampicillin) resistance marker wwwwikipediaorg

Riboflavin (Vitamin B2)

httpwwwocrawdogcomcat-chickenhtm

Colored scanning electron micrographs of representative cheese starter (A-C) and nonstarter (D-F) lactic acid bacteria (LAB) Lactobacillus helveticus (A) Lb delbrueckii subsp bulgaricus (B) Lactococcus lactis (C) Lb casei (D) Pediococcus pentosaceus (E) and Lb brevis (F)

Cheese

Microorganisms ndash fermented products

Microorganisms ndash fermented products

McSweeney P(2004) Biochemistry of cheese ripening Vol 57 (2-3) Int J Dairy Technol

Cheese_ Emmental

Microorganisms ndash fermented products

ldquoIn the late stage of cheese production P freudenreichii consumes the lactic acid excreted by the other bacteria and releases carbon dioxide gas which slowly forms the bubbles that make holesrdquo wwwwikipediaorg

Streptococcus thermophilus Lactobacillus debrueckii helveticus and Propionibacterium freudenreichii

Cheese_ Gouda

Microorganisms ndash fermented products

Lactococcus lactis ssp cremoris lactis Leuconostoc mesenteroides ssp cremoris

Leuconostoc mesenteroides ssp cremoris are starter cultures used for flavor and aroma development through the production of diacetyl from citrate

Roquefort

Microorganisms ndash fermented products

Camembert

ldquoPenicillium roqueforti and Penicillium caseicolum possess very potent proteolytic systems The molds secrete acid and neutral metalloproteinases and several aminopeptidases and carboxypeptidases The mycelia also contain intracellular proteinases and peptidases that are probably released when the mould dies and lysesrdquo

Microorganisms ndash fermented products

Fermented milks

Microorganisms ndash fermented products

Fermented milks

ldquoKefir grains are a combination of bacteria and yeasts in a matrix of proteins lipids and sugars and this symbiotic matrix forms grains that resemble cauliflower For this reason a complex and highly variable community of lactic acid bacteria and yeasts can be found in these grainsrdquo wwwwikipediaorg

Genus Lactobacillus Leuconostoc Pediococcus Streptococcus Bifidobacerium

Microorganisms ndash fermented products Fermented meats

Hutkins Robert W Microbiology and Technology of Fermented Foods

Pediococcus pentosaceus

httpbiowebusueduemlabcurrent20newshtml

Microorganisms ndash fermented products

Meat cultures

Lactobacillus sakei 10000-times magnified (Bild Joumlrg Groth Blessing Biotech GmbH)

Lactobacillus curvatus Lactobacillus plantarum Lactobacillus pentosus Streptococcus carnosus Micrococcus varians

httpwwwwzwtumdeindexphpid=185ampL=1amptx_ttnews5Btt_news5D=280

Microorganisms ndash fermented products

Meat cultures

httpwwwchr-hansencomproductsproduct-areasmeat-cultureshtml

Microorganisms ndash fermented products

Salami

ldquoPenicillium nalgiovense P chrysogenum and P camenberti used as starters The mold is desired as it imparts flavor helps the drying process prevents spoilage (mainly preventing growth of other mycotoxin-producing moulds during the curing process) and give a typical white color on the surfacerdquo

Microorganisms ndash fermented products

Wine amp Beer

Microorganisms ndash fermented products

Wine amp Beer

ldquoDuring fermentation the yeast converts the sugar in the wort to alcohol and carbon dioxide in addition to small amounts of glycerol and acetic acidrdquo

Yeast of the species Saccharomyces cerevisiae

httpenwikipediaorgwikiYeast

Microorganisms ndash other fermented products

httpwwwpsmicrographscoukrhizopus-mould--rhizopus-oligosporus-science-image80012871

Tempeh

Tempeh is manufactured from soaked boiled and dired soybeans that are inoculated with mold spores of species of Rhizopus (R stolonifer R oryzae R oigosporus or R arrhizus) The mash is packed or rolled in banana leaves and then incubated until there is good growth of mycelium but little sporulation Machve KK Fermentation Technology 2009

Functional food components

Critical Reviews in Food Science and Nutrition Structural Design Principles for Delivery of Bioactive Components in Nutraceuticals and Functional Foods 2011 McClements J Andrew E Yeonhwa D amp Weiss J

BioBest Omega 3 probiotic yogurt is a source of omega-3 PUFA that are considered an important part of a healthy diet It also contains over 1 billion active probiotic cultures Lactobacillus acidophilus NCFM Bifidobacterium lactis Bi-07 per serving that contribute to healthy digestive tract flora httpwwwastrocaproductsbiobest_omega_3_12x100g_multipackUbJJb_nVA8s

Functional food components ndash Omega 3

Inhibition of β-carotene degradation in oil-in-water nanoemulsions Influence of oil-soluble and water-soluble antioxidants Cheng Qian Eric Andrew Decker Hang Xiao David Julian McClements Volume 135 Issue 3 1 December 2012 Pages 1036ndash1043

Functional food components ndash Carotenoids

β-carotene enriched oil-in-water nanoemulsions stabilized by different emulsifiers with either no antioxidants (control) or antioxidants (80 μM EDTA + 10000 ppm vitamin E acetate)

Functional food components ndash Polyphenols

Pomegranate Phenolics from the Peels Arils and Flowers Are Antiatherogenic Studies in Vivo in Atherosclerotic Apolipoprotein E-Deficient (E0) Mice and in Vitro in Cultured Macrophages and Lipoproteins J Agric Food Chem 2008 56 (3) pp 1148ndash1157

Pomegranate phenolics and mainly oligomers punicalagin punicalin and gallic and ellagic acids are major contributors to the beneficial effects of pomegranate juice

Functional food components ndash Antioxidant activity

J Med Food 2012 Nov15(11)968-73 doi 101089jmf20122282 Epub 2012 Oct 12 Prickly pear cactus (Opuntia ficus indica var saboten) protects against stress-induced acute gastric lesions in rats (maltodextrin y betanin)

httpcancerpreventionresearchaacrjournalsorgcontentearly200906191940-6207CAPR-08-0167abstract

Tea Polyphenols Decrease Serum Levels of Prostate-Specific Antigen Hepatocyte Growth Factor and Vascular Endothelial Growth Factor in Prostate Cancer Patients and Inhibit Production of Hepatocyte Growth Factor and Vascular Endothelial Growth Factor In vitro 2008 Jerry McLarty Rebecca LH Bigelow Mylinh Smith Don Elmajian Murali Ankem James A Cardelli

Functional food components ndash Polyphenols

ldquoNano-sized self assembled structured liquids = nanodrops Liquid carriers that pass through the digestive system effectively without sinking or breaking up to the absorption site These nanodrops carry the phytosterols to the large micelles that the body produces from the bile acid where they compete with cholesterol for entry into the micelle The phytosterols enter the micelle thereby inhibiting transportation of cholesterol from the digestive system into the bloodstreamrdquo Shemen Industries

Functional food components ndash Phytosterols

Goacutemez-Guilleacuten M C B Gimeacutenez et al (2011) Functional and bioactive properties of collagen and gelatin from alternative sources A review Food Hydrocolloids 25(8) 1813-1827

Functional food components ndash Bioactive peptides

httpwwwnuritascomscreening-mining-food-for-bioactive-peptides

Health and nutrition benefits associated with Fibregum its fermentation in the large bowel increases levels of beneficial bacteria which stimulates the production of short-chain fatty acids (SCFAs) that have such properties as lowering serum cholesterol it is a strong prebiotic helping to balance the intestinal microbial ecosystem in the distal colon

Functional food components ndash Prebiotic fiber

httpwwwnexiracomFibregumE284A2-healthy-prebiotic-fiber_6html

Senegalia senegal (acacia)

Functional food components ndash Essential minerals (Fe Zn Ca Se)

httpwwwfdagovFoodGuidanceRegulationGuidanceDocumentsRegulatoryInformationLabelingNutritionucm152626htm

Pseudocereals are considered an important energy source due to their starch content they also provide good quality protein dietary fibre and lipids rich in unsaturated fats They contain adequate levels of minerals and vitamins and significant amounts of other bioactive components such as saponins phytosterols squalene fagopyritols and polyphenols

Functional food components ndash micronutrients

httpquinuapewp-contentuploads201302antiox-Gallagherpdf

Seven-step process would ensure that functional foods are safe and effective with health claims that are accurate and regulatory oversight that is science based and efficient

Functional foods

FERGUS CLYDESDALE 2004 Functional Foods Opportunities amp Challenges Food Technology December 2004 Volume 58 No12

httpwwwgooglecompatentsUS20100196569

httpwwwgooglecompatentsWO2006048158A1cl=en

httpswwwgooglecompatentsUS6428824pg=PA2ampdq=Lepidium+peruvianumamphl=enampsa=Xampei=KxK2UanpKvOu4AOehICgDwampved=0CDoQ6AEwATgK

httpswwwgooglecompatentsUS7005148pg=PA3ampdq=vaccinium+corymbosumamphl=enampsa=Xampei=-xK2UZ7vF_a64AO0soG4Cgampsqi=2amppjf=1ampved=0CGwQ6AEwCA

httpswwwgooglecompatentsWO2001045648A2cl=enampdq=vaccinium+corymbosumamphl=enampsa=Xampei=9BO2Uc_5A9Sz4AOrsIEIampved=0CDQQ6AEwAA

Potential for future researchhellip

Top health issues consumers are concerned about preventing From NMI(2005)

A ELIZABETH SLOAN 2006 Top 10 Functional Food Trends Food Technology Volume 60 No 4

Functional food components

Fatty acids [CLA Omegas]

Carotenoids

Phytosterols

Bioactive peptides

Bioactive CHOrsquos

Essential minerals

Antioxidants

Enzymes ndash cleaning agents

The protease enzyme in Tergazyme is Bacillus licheniformis subtilisin carlsberg and is used for the cleaning of dairy equipment laboratory ware reverse osmosis and ultrafiltration membranes and units

Enzymes ndash cleaning agents

httpwwwphschoolcomsciencebiology_placelabbenchlab2conceptshtml

Catalase is used for the removal of H2O2 which is used as both a bleaching agent and an antimicrobial

httpwwwinlgovresearchultrastable-catalase-enzyme

Enzymes ndash antimicrobials

httpwwwnaturecomsrep2013130402srep01584fullsrep01584html

Ply500 is an isolated cell lytic enzyme with peptidase activity against certain L monocytogenes serotypes

Phages on the surface of an Escherichia coli cell Source Eye of ScienceScience

Enzymes ndash ELISA

ldquoAntigens from the sample are attached to a surface Then a further specific antibody is applied over the surface so it can bind to the antigen This antibody is linked to an enzyme and in the final step a substance containing the enzymes substrate is added The subsequent reaction produces a detectable signal most commonly a color change in the substraterdquo

httpthefutureofthingscomarticles37biopen-senses-biothreatshtml

Enzymes ndash for food processing

httpwwwnovasepcombiomoleculesfood-ingredientsApplicationssugar-and-sweeteners-productionasp

Amylase

ldquoAmylases in breadmaking break down complex sugars such as starch (found in flour) into simple sugars Yeast then feeds on these simple sugars and converts it into the waste products of alcohol and CO2 This imparts flavour and causes the bread to riserdquo

Amylase

Enzymes ndash for food processing

In traditional beer brewing malted barley is mixed with hot water to create a mash which is held at a given temperature to allow the amylases in the malted grain to convert the barleys starch into sugars Different temperatures optimize the activity of alpha or beta amylase resulting in different mixtures of fermentable and unfermentable sugars

Enzymes ndash for food processing

Enzymes ndash for food processing

Lactase

ldquoLactase produced commercially can be extracted both from yeasts such as Kluyveromyces fragilis and Kluyveromyces lactis and from fungi such as Aspergillus niger and Aspergillus oryzae Its primary commercial use is to break down lactose in milk to make it suitable for people with lactose intolerancerdquo wwwwikipediaorg

Enzymes ndash for food processing Protease

Calf rennet

Vegetable rennet Cynara cardunculus

Fermentation-produced chymosin Aspergillus niger var awamori GM

Enzymes ndash for food processing Protease

Papain

Meat is sprinkled with the powder and the enzymes help to break down the meat fibers

httpwwwenzymedevelopmentcomapplicationstenderizer

Use of Mucor miehei Lipase to Improve Functional Properties of Yolk-Contaminated Egg Whites Laura N Macherey Frank D Conforti William Eigel III Sean F OrsquoKeefe Journal of Food Science Volume 76 Issue 4 pages C651ndashC655 May 2011

Enzymes ndash for food processing

Lipase

Microorganisms ndash ingredients production

ldquoCorynebacterium glutamicum was discovered in the 1950s in Japan as natural producer of glutamic acid It is now produced by direct fermentation used for industrial production of amino acids which are used as flavour enhancers in foodrdquo

Glutamic acid amp Lysine

httpbacmapwishartlabcomorganisms485

Microorganisms ndash ingredients production

Citric acid

ldquoCultures of A niger are fed on a sucrose or glucose-containing medium to produce citric acid The source of sugar is corn steep liquor molasses hydrolyzed corn starch or other inexpensive sugary solutionsrdquo

httpgenomejgi-psforgAspni5Aspni5homehtml

Microorganisms ndash ingredients production

Bacillus subtilis has been genetically modified to both increase the bacterias production of riboflavin and to introduce an antibiotic (ampicillin) resistance marker wwwwikipediaorg

Riboflavin (Vitamin B2)

httpwwwocrawdogcomcat-chickenhtm

Colored scanning electron micrographs of representative cheese starter (A-C) and nonstarter (D-F) lactic acid bacteria (LAB) Lactobacillus helveticus (A) Lb delbrueckii subsp bulgaricus (B) Lactococcus lactis (C) Lb casei (D) Pediococcus pentosaceus (E) and Lb brevis (F)

Cheese

Microorganisms ndash fermented products

Microorganisms ndash fermented products

McSweeney P(2004) Biochemistry of cheese ripening Vol 57 (2-3) Int J Dairy Technol

Cheese_ Emmental

Microorganisms ndash fermented products

ldquoIn the late stage of cheese production P freudenreichii consumes the lactic acid excreted by the other bacteria and releases carbon dioxide gas which slowly forms the bubbles that make holesrdquo wwwwikipediaorg

Streptococcus thermophilus Lactobacillus debrueckii helveticus and Propionibacterium freudenreichii

Cheese_ Gouda

Microorganisms ndash fermented products

Lactococcus lactis ssp cremoris lactis Leuconostoc mesenteroides ssp cremoris

Leuconostoc mesenteroides ssp cremoris are starter cultures used for flavor and aroma development through the production of diacetyl from citrate

Roquefort

Microorganisms ndash fermented products

Camembert

ldquoPenicillium roqueforti and Penicillium caseicolum possess very potent proteolytic systems The molds secrete acid and neutral metalloproteinases and several aminopeptidases and carboxypeptidases The mycelia also contain intracellular proteinases and peptidases that are probably released when the mould dies and lysesrdquo

Microorganisms ndash fermented products

Fermented milks

Microorganisms ndash fermented products

Fermented milks

ldquoKefir grains are a combination of bacteria and yeasts in a matrix of proteins lipids and sugars and this symbiotic matrix forms grains that resemble cauliflower For this reason a complex and highly variable community of lactic acid bacteria and yeasts can be found in these grainsrdquo wwwwikipediaorg

Genus Lactobacillus Leuconostoc Pediococcus Streptococcus Bifidobacerium

Microorganisms ndash fermented products Fermented meats

Hutkins Robert W Microbiology and Technology of Fermented Foods

Pediococcus pentosaceus

httpbiowebusueduemlabcurrent20newshtml

Microorganisms ndash fermented products

Meat cultures

Lactobacillus sakei 10000-times magnified (Bild Joumlrg Groth Blessing Biotech GmbH)

Lactobacillus curvatus Lactobacillus plantarum Lactobacillus pentosus Streptococcus carnosus Micrococcus varians

httpwwwwzwtumdeindexphpid=185ampL=1amptx_ttnews5Btt_news5D=280

Microorganisms ndash fermented products

Meat cultures

httpwwwchr-hansencomproductsproduct-areasmeat-cultureshtml

Microorganisms ndash fermented products

Salami

ldquoPenicillium nalgiovense P chrysogenum and P camenberti used as starters The mold is desired as it imparts flavor helps the drying process prevents spoilage (mainly preventing growth of other mycotoxin-producing moulds during the curing process) and give a typical white color on the surfacerdquo

Microorganisms ndash fermented products

Wine amp Beer

Microorganisms ndash fermented products

Wine amp Beer

ldquoDuring fermentation the yeast converts the sugar in the wort to alcohol and carbon dioxide in addition to small amounts of glycerol and acetic acidrdquo

Yeast of the species Saccharomyces cerevisiae

httpenwikipediaorgwikiYeast

Microorganisms ndash other fermented products

httpwwwpsmicrographscoukrhizopus-mould--rhizopus-oligosporus-science-image80012871

Tempeh

Tempeh is manufactured from soaked boiled and dired soybeans that are inoculated with mold spores of species of Rhizopus (R stolonifer R oryzae R oigosporus or R arrhizus) The mash is packed or rolled in banana leaves and then incubated until there is good growth of mycelium but little sporulation Machve KK Fermentation Technology 2009

Functional food components

Critical Reviews in Food Science and Nutrition Structural Design Principles for Delivery of Bioactive Components in Nutraceuticals and Functional Foods 2011 McClements J Andrew E Yeonhwa D amp Weiss J

BioBest Omega 3 probiotic yogurt is a source of omega-3 PUFA that are considered an important part of a healthy diet It also contains over 1 billion active probiotic cultures Lactobacillus acidophilus NCFM Bifidobacterium lactis Bi-07 per serving that contribute to healthy digestive tract flora httpwwwastrocaproductsbiobest_omega_3_12x100g_multipackUbJJb_nVA8s

Functional food components ndash Omega 3

Inhibition of β-carotene degradation in oil-in-water nanoemulsions Influence of oil-soluble and water-soluble antioxidants Cheng Qian Eric Andrew Decker Hang Xiao David Julian McClements Volume 135 Issue 3 1 December 2012 Pages 1036ndash1043

Functional food components ndash Carotenoids

β-carotene enriched oil-in-water nanoemulsions stabilized by different emulsifiers with either no antioxidants (control) or antioxidants (80 μM EDTA + 10000 ppm vitamin E acetate)

Functional food components ndash Polyphenols

Pomegranate Phenolics from the Peels Arils and Flowers Are Antiatherogenic Studies in Vivo in Atherosclerotic Apolipoprotein E-Deficient (E0) Mice and in Vitro in Cultured Macrophages and Lipoproteins J Agric Food Chem 2008 56 (3) pp 1148ndash1157

Pomegranate phenolics and mainly oligomers punicalagin punicalin and gallic and ellagic acids are major contributors to the beneficial effects of pomegranate juice

Functional food components ndash Antioxidant activity

J Med Food 2012 Nov15(11)968-73 doi 101089jmf20122282 Epub 2012 Oct 12 Prickly pear cactus (Opuntia ficus indica var saboten) protects against stress-induced acute gastric lesions in rats (maltodextrin y betanin)

httpcancerpreventionresearchaacrjournalsorgcontentearly200906191940-6207CAPR-08-0167abstract

Tea Polyphenols Decrease Serum Levels of Prostate-Specific Antigen Hepatocyte Growth Factor and Vascular Endothelial Growth Factor in Prostate Cancer Patients and Inhibit Production of Hepatocyte Growth Factor and Vascular Endothelial Growth Factor In vitro 2008 Jerry McLarty Rebecca LH Bigelow Mylinh Smith Don Elmajian Murali Ankem James A Cardelli

Functional food components ndash Polyphenols

ldquoNano-sized self assembled structured liquids = nanodrops Liquid carriers that pass through the digestive system effectively without sinking or breaking up to the absorption site These nanodrops carry the phytosterols to the large micelles that the body produces from the bile acid where they compete with cholesterol for entry into the micelle The phytosterols enter the micelle thereby inhibiting transportation of cholesterol from the digestive system into the bloodstreamrdquo Shemen Industries

Functional food components ndash Phytosterols

Goacutemez-Guilleacuten M C B Gimeacutenez et al (2011) Functional and bioactive properties of collagen and gelatin from alternative sources A review Food Hydrocolloids 25(8) 1813-1827

Functional food components ndash Bioactive peptides

httpwwwnuritascomscreening-mining-food-for-bioactive-peptides

Health and nutrition benefits associated with Fibregum its fermentation in the large bowel increases levels of beneficial bacteria which stimulates the production of short-chain fatty acids (SCFAs) that have such properties as lowering serum cholesterol it is a strong prebiotic helping to balance the intestinal microbial ecosystem in the distal colon

Functional food components ndash Prebiotic fiber

httpwwwnexiracomFibregumE284A2-healthy-prebiotic-fiber_6html

Senegalia senegal (acacia)

Functional food components ndash Essential minerals (Fe Zn Ca Se)

httpwwwfdagovFoodGuidanceRegulationGuidanceDocumentsRegulatoryInformationLabelingNutritionucm152626htm

Pseudocereals are considered an important energy source due to their starch content they also provide good quality protein dietary fibre and lipids rich in unsaturated fats They contain adequate levels of minerals and vitamins and significant amounts of other bioactive components such as saponins phytosterols squalene fagopyritols and polyphenols

Functional food components ndash micronutrients

httpquinuapewp-contentuploads201302antiox-Gallagherpdf

Seven-step process would ensure that functional foods are safe and effective with health claims that are accurate and regulatory oversight that is science based and efficient

Functional foods

FERGUS CLYDESDALE 2004 Functional Foods Opportunities amp Challenges Food Technology December 2004 Volume 58 No12

httpwwwgooglecompatentsUS20100196569

httpwwwgooglecompatentsWO2006048158A1cl=en

httpswwwgooglecompatentsUS6428824pg=PA2ampdq=Lepidium+peruvianumamphl=enampsa=Xampei=KxK2UanpKvOu4AOehICgDwampved=0CDoQ6AEwATgK

httpswwwgooglecompatentsUS7005148pg=PA3ampdq=vaccinium+corymbosumamphl=enampsa=Xampei=-xK2UZ7vF_a64AO0soG4Cgampsqi=2amppjf=1ampved=0CGwQ6AEwCA

httpswwwgooglecompatentsWO2001045648A2cl=enampdq=vaccinium+corymbosumamphl=enampsa=Xampei=9BO2Uc_5A9Sz4AOrsIEIampved=0CDQQ6AEwAA

Potential for future researchhellip

Top health issues consumers are concerned about preventing From NMI(2005)

A ELIZABETH SLOAN 2006 Top 10 Functional Food Trends Food Technology Volume 60 No 4

Enzymes ndash cleaning agents

The protease enzyme in Tergazyme is Bacillus licheniformis subtilisin carlsberg and is used for the cleaning of dairy equipment laboratory ware reverse osmosis and ultrafiltration membranes and units

Enzymes ndash cleaning agents

httpwwwphschoolcomsciencebiology_placelabbenchlab2conceptshtml

Catalase is used for the removal of H2O2 which is used as both a bleaching agent and an antimicrobial

httpwwwinlgovresearchultrastable-catalase-enzyme

Enzymes ndash antimicrobials

httpwwwnaturecomsrep2013130402srep01584fullsrep01584html

Ply500 is an isolated cell lytic enzyme with peptidase activity against certain L monocytogenes serotypes

Phages on the surface of an Escherichia coli cell Source Eye of ScienceScience

Enzymes ndash ELISA

ldquoAntigens from the sample are attached to a surface Then a further specific antibody is applied over the surface so it can bind to the antigen This antibody is linked to an enzyme and in the final step a substance containing the enzymes substrate is added The subsequent reaction produces a detectable signal most commonly a color change in the substraterdquo

httpthefutureofthingscomarticles37biopen-senses-biothreatshtml

Enzymes ndash for food processing

httpwwwnovasepcombiomoleculesfood-ingredientsApplicationssugar-and-sweeteners-productionasp

Amylase

ldquoAmylases in breadmaking break down complex sugars such as starch (found in flour) into simple sugars Yeast then feeds on these simple sugars and converts it into the waste products of alcohol and CO2 This imparts flavour and causes the bread to riserdquo

Amylase

Enzymes ndash for food processing

In traditional beer brewing malted barley is mixed with hot water to create a mash which is held at a given temperature to allow the amylases in the malted grain to convert the barleys starch into sugars Different temperatures optimize the activity of alpha or beta amylase resulting in different mixtures of fermentable and unfermentable sugars

Enzymes ndash for food processing

Enzymes ndash for food processing

Lactase

ldquoLactase produced commercially can be extracted both from yeasts such as Kluyveromyces fragilis and Kluyveromyces lactis and from fungi such as Aspergillus niger and Aspergillus oryzae Its primary commercial use is to break down lactose in milk to make it suitable for people with lactose intolerancerdquo wwwwikipediaorg

Enzymes ndash for food processing Protease

Calf rennet

Vegetable rennet Cynara cardunculus

Fermentation-produced chymosin Aspergillus niger var awamori GM

Enzymes ndash for food processing Protease

Papain

Meat is sprinkled with the powder and the enzymes help to break down the meat fibers

httpwwwenzymedevelopmentcomapplicationstenderizer

Use of Mucor miehei Lipase to Improve Functional Properties of Yolk-Contaminated Egg Whites Laura N Macherey Frank D Conforti William Eigel III Sean F OrsquoKeefe Journal of Food Science Volume 76 Issue 4 pages C651ndashC655 May 2011

Enzymes ndash for food processing

Lipase

Microorganisms ndash ingredients production

ldquoCorynebacterium glutamicum was discovered in the 1950s in Japan as natural producer of glutamic acid It is now produced by direct fermentation used for industrial production of amino acids which are used as flavour enhancers in foodrdquo

Glutamic acid amp Lysine

httpbacmapwishartlabcomorganisms485

Microorganisms ndash ingredients production

Citric acid

ldquoCultures of A niger are fed on a sucrose or glucose-containing medium to produce citric acid The source of sugar is corn steep liquor molasses hydrolyzed corn starch or other inexpensive sugary solutionsrdquo

httpgenomejgi-psforgAspni5Aspni5homehtml

Microorganisms ndash ingredients production

Bacillus subtilis has been genetically modified to both increase the bacterias production of riboflavin and to introduce an antibiotic (ampicillin) resistance marker wwwwikipediaorg

Riboflavin (Vitamin B2)

httpwwwocrawdogcomcat-chickenhtm

Colored scanning electron micrographs of representative cheese starter (A-C) and nonstarter (D-F) lactic acid bacteria (LAB) Lactobacillus helveticus (A) Lb delbrueckii subsp bulgaricus (B) Lactococcus lactis (C) Lb casei (D) Pediococcus pentosaceus (E) and Lb brevis (F)

Cheese

Microorganisms ndash fermented products

Microorganisms ndash fermented products

McSweeney P(2004) Biochemistry of cheese ripening Vol 57 (2-3) Int J Dairy Technol

Cheese_ Emmental

Microorganisms ndash fermented products

ldquoIn the late stage of cheese production P freudenreichii consumes the lactic acid excreted by the other bacteria and releases carbon dioxide gas which slowly forms the bubbles that make holesrdquo wwwwikipediaorg

Streptococcus thermophilus Lactobacillus debrueckii helveticus and Propionibacterium freudenreichii

Cheese_ Gouda

Microorganisms ndash fermented products

Lactococcus lactis ssp cremoris lactis Leuconostoc mesenteroides ssp cremoris

Leuconostoc mesenteroides ssp cremoris are starter cultures used for flavor and aroma development through the production of diacetyl from citrate

Roquefort

Microorganisms ndash fermented products

Camembert

ldquoPenicillium roqueforti and Penicillium caseicolum possess very potent proteolytic systems The molds secrete acid and neutral metalloproteinases and several aminopeptidases and carboxypeptidases The mycelia also contain intracellular proteinases and peptidases that are probably released when the mould dies and lysesrdquo

Microorganisms ndash fermented products

Fermented milks

Microorganisms ndash fermented products

Fermented milks

ldquoKefir grains are a combination of bacteria and yeasts in a matrix of proteins lipids and sugars and this symbiotic matrix forms grains that resemble cauliflower For this reason a complex and highly variable community of lactic acid bacteria and yeasts can be found in these grainsrdquo wwwwikipediaorg

Genus Lactobacillus Leuconostoc Pediococcus Streptococcus Bifidobacerium

Microorganisms ndash fermented products Fermented meats

Hutkins Robert W Microbiology and Technology of Fermented Foods

Pediococcus pentosaceus

httpbiowebusueduemlabcurrent20newshtml

Microorganisms ndash fermented products

Meat cultures

Lactobacillus sakei 10000-times magnified (Bild Joumlrg Groth Blessing Biotech GmbH)

Lactobacillus curvatus Lactobacillus plantarum Lactobacillus pentosus Streptococcus carnosus Micrococcus varians

httpwwwwzwtumdeindexphpid=185ampL=1amptx_ttnews5Btt_news5D=280

Microorganisms ndash fermented products

Meat cultures

httpwwwchr-hansencomproductsproduct-areasmeat-cultureshtml

Microorganisms ndash fermented products

Salami

ldquoPenicillium nalgiovense P chrysogenum and P camenberti used as starters The mold is desired as it imparts flavor helps the drying process prevents spoilage (mainly preventing growth of other mycotoxin-producing moulds during the curing process) and give a typical white color on the surfacerdquo

Microorganisms ndash fermented products

Wine amp Beer

Microorganisms ndash fermented products

Wine amp Beer

ldquoDuring fermentation the yeast converts the sugar in the wort to alcohol and carbon dioxide in addition to small amounts of glycerol and acetic acidrdquo

Yeast of the species Saccharomyces cerevisiae

httpenwikipediaorgwikiYeast

Microorganisms ndash other fermented products

httpwwwpsmicrographscoukrhizopus-mould--rhizopus-oligosporus-science-image80012871

Tempeh

Tempeh is manufactured from soaked boiled and dired soybeans that are inoculated with mold spores of species of Rhizopus (R stolonifer R oryzae R oigosporus or R arrhizus) The mash is packed or rolled in banana leaves and then incubated until there is good growth of mycelium but little sporulation Machve KK Fermentation Technology 2009

Functional food components

Critical Reviews in Food Science and Nutrition Structural Design Principles for Delivery of Bioactive Components in Nutraceuticals and Functional Foods 2011 McClements J Andrew E Yeonhwa D amp Weiss J

BioBest Omega 3 probiotic yogurt is a source of omega-3 PUFA that are considered an important part of a healthy diet It also contains over 1 billion active probiotic cultures Lactobacillus acidophilus NCFM Bifidobacterium lactis Bi-07 per serving that contribute to healthy digestive tract flora httpwwwastrocaproductsbiobest_omega_3_12x100g_multipackUbJJb_nVA8s

Functional food components ndash Omega 3

Inhibition of β-carotene degradation in oil-in-water nanoemulsions Influence of oil-soluble and water-soluble antioxidants Cheng Qian Eric Andrew Decker Hang Xiao David Julian McClements Volume 135 Issue 3 1 December 2012 Pages 1036ndash1043

Functional food components ndash Carotenoids

β-carotene enriched oil-in-water nanoemulsions stabilized by different emulsifiers with either no antioxidants (control) or antioxidants (80 μM EDTA + 10000 ppm vitamin E acetate)

Functional food components ndash Polyphenols

Pomegranate Phenolics from the Peels Arils and Flowers Are Antiatherogenic Studies in Vivo in Atherosclerotic Apolipoprotein E-Deficient (E0) Mice and in Vitro in Cultured Macrophages and Lipoproteins J Agric Food Chem 2008 56 (3) pp 1148ndash1157

Pomegranate phenolics and mainly oligomers punicalagin punicalin and gallic and ellagic acids are major contributors to the beneficial effects of pomegranate juice

Functional food components ndash Antioxidant activity

J Med Food 2012 Nov15(11)968-73 doi 101089jmf20122282 Epub 2012 Oct 12 Prickly pear cactus (Opuntia ficus indica var saboten) protects against stress-induced acute gastric lesions in rats (maltodextrin y betanin)

httpcancerpreventionresearchaacrjournalsorgcontentearly200906191940-6207CAPR-08-0167abstract

Tea Polyphenols Decrease Serum Levels of Prostate-Specific Antigen Hepatocyte Growth Factor and Vascular Endothelial Growth Factor in Prostate Cancer Patients and Inhibit Production of Hepatocyte Growth Factor and Vascular Endothelial Growth Factor In vitro 2008 Jerry McLarty Rebecca LH Bigelow Mylinh Smith Don Elmajian Murali Ankem James A Cardelli

Functional food components ndash Polyphenols

ldquoNano-sized self assembled structured liquids = nanodrops Liquid carriers that pass through the digestive system effectively without sinking or breaking up to the absorption site These nanodrops carry the phytosterols to the large micelles that the body produces from the bile acid where they compete with cholesterol for entry into the micelle The phytosterols enter the micelle thereby inhibiting transportation of cholesterol from the digestive system into the bloodstreamrdquo Shemen Industries

Functional food components ndash Phytosterols

Goacutemez-Guilleacuten M C B Gimeacutenez et al (2011) Functional and bioactive properties of collagen and gelatin from alternative sources A review Food Hydrocolloids 25(8) 1813-1827

Functional food components ndash Bioactive peptides

httpwwwnuritascomscreening-mining-food-for-bioactive-peptides

Health and nutrition benefits associated with Fibregum its fermentation in the large bowel increases levels of beneficial bacteria which stimulates the production of short-chain fatty acids (SCFAs) that have such properties as lowering serum cholesterol it is a strong prebiotic helping to balance the intestinal microbial ecosystem in the distal colon

Functional food components ndash Prebiotic fiber

httpwwwnexiracomFibregumE284A2-healthy-prebiotic-fiber_6html

Senegalia senegal (acacia)

Functional food components ndash Essential minerals (Fe Zn Ca Se)

httpwwwfdagovFoodGuidanceRegulationGuidanceDocumentsRegulatoryInformationLabelingNutritionucm152626htm

Pseudocereals are considered an important energy source due to their starch content they also provide good quality protein dietary fibre and lipids rich in unsaturated fats They contain adequate levels of minerals and vitamins and significant amounts of other bioactive components such as saponins phytosterols squalene fagopyritols and polyphenols

Functional food components ndash micronutrients

httpquinuapewp-contentuploads201302antiox-Gallagherpdf

Seven-step process would ensure that functional foods are safe and effective with health claims that are accurate and regulatory oversight that is science based and efficient

Functional foods

FERGUS CLYDESDALE 2004 Functional Foods Opportunities amp Challenges Food Technology December 2004 Volume 58 No12

httpwwwgooglecompatentsUS20100196569

httpwwwgooglecompatentsWO2006048158A1cl=en

httpswwwgooglecompatentsUS6428824pg=PA2ampdq=Lepidium+peruvianumamphl=enampsa=Xampei=KxK2UanpKvOu4AOehICgDwampved=0CDoQ6AEwATgK

httpswwwgooglecompatentsUS7005148pg=PA3ampdq=vaccinium+corymbosumamphl=enampsa=Xampei=-xK2UZ7vF_a64AO0soG4Cgampsqi=2amppjf=1ampved=0CGwQ6AEwCA

httpswwwgooglecompatentsWO2001045648A2cl=enampdq=vaccinium+corymbosumamphl=enampsa=Xampei=9BO2Uc_5A9Sz4AOrsIEIampved=0CDQQ6AEwAA

Potential for future researchhellip

Top health issues consumers are concerned about preventing From NMI(2005)

A ELIZABETH SLOAN 2006 Top 10 Functional Food Trends Food Technology Volume 60 No 4

Enzymes ndash cleaning agents

httpwwwphschoolcomsciencebiology_placelabbenchlab2conceptshtml

Catalase is used for the removal of H2O2 which is used as both a bleaching agent and an antimicrobial

httpwwwinlgovresearchultrastable-catalase-enzyme

Enzymes ndash antimicrobials

httpwwwnaturecomsrep2013130402srep01584fullsrep01584html

Ply500 is an isolated cell lytic enzyme with peptidase activity against certain L monocytogenes serotypes

Phages on the surface of an Escherichia coli cell Source Eye of ScienceScience

Enzymes ndash ELISA

ldquoAntigens from the sample are attached to a surface Then a further specific antibody is applied over the surface so it can bind to the antigen This antibody is linked to an enzyme and in the final step a substance containing the enzymes substrate is added The subsequent reaction produces a detectable signal most commonly a color change in the substraterdquo

httpthefutureofthingscomarticles37biopen-senses-biothreatshtml

Enzymes ndash for food processing

httpwwwnovasepcombiomoleculesfood-ingredientsApplicationssugar-and-sweeteners-productionasp

Amylase

ldquoAmylases in breadmaking break down complex sugars such as starch (found in flour) into simple sugars Yeast then feeds on these simple sugars and converts it into the waste products of alcohol and CO2 This imparts flavour and causes the bread to riserdquo

Amylase

Enzymes ndash for food processing

In traditional beer brewing malted barley is mixed with hot water to create a mash which is held at a given temperature to allow the amylases in the malted grain to convert the barleys starch into sugars Different temperatures optimize the activity of alpha or beta amylase resulting in different mixtures of fermentable and unfermentable sugars

Enzymes ndash for food processing

Enzymes ndash for food processing

Lactase

ldquoLactase produced commercially can be extracted both from yeasts such as Kluyveromyces fragilis and Kluyveromyces lactis and from fungi such as Aspergillus niger and Aspergillus oryzae Its primary commercial use is to break down lactose in milk to make it suitable for people with lactose intolerancerdquo wwwwikipediaorg

Enzymes ndash for food processing Protease

Calf rennet

Vegetable rennet Cynara cardunculus

Fermentation-produced chymosin Aspergillus niger var awamori GM

Enzymes ndash for food processing Protease

Papain

Meat is sprinkled with the powder and the enzymes help to break down the meat fibers

httpwwwenzymedevelopmentcomapplicationstenderizer

Use of Mucor miehei Lipase to Improve Functional Properties of Yolk-Contaminated Egg Whites Laura N Macherey Frank D Conforti William Eigel III Sean F OrsquoKeefe Journal of Food Science Volume 76 Issue 4 pages C651ndashC655 May 2011

Enzymes ndash for food processing

Lipase

Microorganisms ndash ingredients production

ldquoCorynebacterium glutamicum was discovered in the 1950s in Japan as natural producer of glutamic acid It is now produced by direct fermentation used for industrial production of amino acids which are used as flavour enhancers in foodrdquo

Glutamic acid amp Lysine

httpbacmapwishartlabcomorganisms485

Microorganisms ndash ingredients production

Citric acid

ldquoCultures of A niger are fed on a sucrose or glucose-containing medium to produce citric acid The source of sugar is corn steep liquor molasses hydrolyzed corn starch or other inexpensive sugary solutionsrdquo

httpgenomejgi-psforgAspni5Aspni5homehtml

Microorganisms ndash ingredients production

Bacillus subtilis has been genetically modified to both increase the bacterias production of riboflavin and to introduce an antibiotic (ampicillin) resistance marker wwwwikipediaorg

Riboflavin (Vitamin B2)

httpwwwocrawdogcomcat-chickenhtm

Colored scanning electron micrographs of representative cheese starter (A-C) and nonstarter (D-F) lactic acid bacteria (LAB) Lactobacillus helveticus (A) Lb delbrueckii subsp bulgaricus (B) Lactococcus lactis (C) Lb casei (D) Pediococcus pentosaceus (E) and Lb brevis (F)

Cheese

Microorganisms ndash fermented products

Microorganisms ndash fermented products

McSweeney P(2004) Biochemistry of cheese ripening Vol 57 (2-3) Int J Dairy Technol

Cheese_ Emmental

Microorganisms ndash fermented products

ldquoIn the late stage of cheese production P freudenreichii consumes the lactic acid excreted by the other bacteria and releases carbon dioxide gas which slowly forms the bubbles that make holesrdquo wwwwikipediaorg

Streptococcus thermophilus Lactobacillus debrueckii helveticus and Propionibacterium freudenreichii

Cheese_ Gouda

Microorganisms ndash fermented products

Lactococcus lactis ssp cremoris lactis Leuconostoc mesenteroides ssp cremoris

Leuconostoc mesenteroides ssp cremoris are starter cultures used for flavor and aroma development through the production of diacetyl from citrate

Roquefort

Microorganisms ndash fermented products

Camembert

ldquoPenicillium roqueforti and Penicillium caseicolum possess very potent proteolytic systems The molds secrete acid and neutral metalloproteinases and several aminopeptidases and carboxypeptidases The mycelia also contain intracellular proteinases and peptidases that are probably released when the mould dies and lysesrdquo

Microorganisms ndash fermented products

Fermented milks

Microorganisms ndash fermented products

Fermented milks

ldquoKefir grains are a combination of bacteria and yeasts in a matrix of proteins lipids and sugars and this symbiotic matrix forms grains that resemble cauliflower For this reason a complex and highly variable community of lactic acid bacteria and yeasts can be found in these grainsrdquo wwwwikipediaorg

Genus Lactobacillus Leuconostoc Pediococcus Streptococcus Bifidobacerium

Microorganisms ndash fermented products Fermented meats

Hutkins Robert W Microbiology and Technology of Fermented Foods

Pediococcus pentosaceus

httpbiowebusueduemlabcurrent20newshtml

Microorganisms ndash fermented products

Meat cultures

Lactobacillus sakei 10000-times magnified (Bild Joumlrg Groth Blessing Biotech GmbH)

Lactobacillus curvatus Lactobacillus plantarum Lactobacillus pentosus Streptococcus carnosus Micrococcus varians

httpwwwwzwtumdeindexphpid=185ampL=1amptx_ttnews5Btt_news5D=280

Microorganisms ndash fermented products

Meat cultures

httpwwwchr-hansencomproductsproduct-areasmeat-cultureshtml

Microorganisms ndash fermented products

Salami

ldquoPenicillium nalgiovense P chrysogenum and P camenberti used as starters The mold is desired as it imparts flavor helps the drying process prevents spoilage (mainly preventing growth of other mycotoxin-producing moulds during the curing process) and give a typical white color on the surfacerdquo

Microorganisms ndash fermented products

Wine amp Beer

Microorganisms ndash fermented products

Wine amp Beer

ldquoDuring fermentation the yeast converts the sugar in the wort to alcohol and carbon dioxide in addition to small amounts of glycerol and acetic acidrdquo

Yeast of the species Saccharomyces cerevisiae

httpenwikipediaorgwikiYeast

Microorganisms ndash other fermented products

httpwwwpsmicrographscoukrhizopus-mould--rhizopus-oligosporus-science-image80012871

Tempeh

Tempeh is manufactured from soaked boiled and dired soybeans that are inoculated with mold spores of species of Rhizopus (R stolonifer R oryzae R oigosporus or R arrhizus) The mash is packed or rolled in banana leaves and then incubated until there is good growth of mycelium but little sporulation Machve KK Fermentation Technology 2009

Functional food components

Critical Reviews in Food Science and Nutrition Structural Design Principles for Delivery of Bioactive Components in Nutraceuticals and Functional Foods 2011 McClements J Andrew E Yeonhwa D amp Weiss J

BioBest Omega 3 probiotic yogurt is a source of omega-3 PUFA that are considered an important part of a healthy diet It also contains over 1 billion active probiotic cultures Lactobacillus acidophilus NCFM Bifidobacterium lactis Bi-07 per serving that contribute to healthy digestive tract flora httpwwwastrocaproductsbiobest_omega_3_12x100g_multipackUbJJb_nVA8s

Functional food components ndash Omega 3

Inhibition of β-carotene degradation in oil-in-water nanoemulsions Influence of oil-soluble and water-soluble antioxidants Cheng Qian Eric Andrew Decker Hang Xiao David Julian McClements Volume 135 Issue 3 1 December 2012 Pages 1036ndash1043

Functional food components ndash Carotenoids

β-carotene enriched oil-in-water nanoemulsions stabilized by different emulsifiers with either no antioxidants (control) or antioxidants (80 μM EDTA + 10000 ppm vitamin E acetate)

Functional food components ndash Polyphenols

Pomegranate Phenolics from the Peels Arils and Flowers Are Antiatherogenic Studies in Vivo in Atherosclerotic Apolipoprotein E-Deficient (E0) Mice and in Vitro in Cultured Macrophages and Lipoproteins J Agric Food Chem 2008 56 (3) pp 1148ndash1157

Pomegranate phenolics and mainly oligomers punicalagin punicalin and gallic and ellagic acids are major contributors to the beneficial effects of pomegranate juice

Functional food components ndash Antioxidant activity

J Med Food 2012 Nov15(11)968-73 doi 101089jmf20122282 Epub 2012 Oct 12 Prickly pear cactus (Opuntia ficus indica var saboten) protects against stress-induced acute gastric lesions in rats (maltodextrin y betanin)

httpcancerpreventionresearchaacrjournalsorgcontentearly200906191940-6207CAPR-08-0167abstract

Tea Polyphenols Decrease Serum Levels of Prostate-Specific Antigen Hepatocyte Growth Factor and Vascular Endothelial Growth Factor in Prostate Cancer Patients and Inhibit Production of Hepatocyte Growth Factor and Vascular Endothelial Growth Factor In vitro 2008 Jerry McLarty Rebecca LH Bigelow Mylinh Smith Don Elmajian Murali Ankem James A Cardelli

Functional food components ndash Polyphenols

ldquoNano-sized self assembled structured liquids = nanodrops Liquid carriers that pass through the digestive system effectively without sinking or breaking up to the absorption site These nanodrops carry the phytosterols to the large micelles that the body produces from the bile acid where they compete with cholesterol for entry into the micelle The phytosterols enter the micelle thereby inhibiting transportation of cholesterol from the digestive system into the bloodstreamrdquo Shemen Industries

Functional food components ndash Phytosterols

Goacutemez-Guilleacuten M C B Gimeacutenez et al (2011) Functional and bioactive properties of collagen and gelatin from alternative sources A review Food Hydrocolloids 25(8) 1813-1827

Functional food components ndash Bioactive peptides

httpwwwnuritascomscreening-mining-food-for-bioactive-peptides

Health and nutrition benefits associated with Fibregum its fermentation in the large bowel increases levels of beneficial bacteria which stimulates the production of short-chain fatty acids (SCFAs) that have such properties as lowering serum cholesterol it is a strong prebiotic helping to balance the intestinal microbial ecosystem in the distal colon

Functional food components ndash Prebiotic fiber

httpwwwnexiracomFibregumE284A2-healthy-prebiotic-fiber_6html

Senegalia senegal (acacia)

Functional food components ndash Essential minerals (Fe Zn Ca Se)

httpwwwfdagovFoodGuidanceRegulationGuidanceDocumentsRegulatoryInformationLabelingNutritionucm152626htm

Pseudocereals are considered an important energy source due to their starch content they also provide good quality protein dietary fibre and lipids rich in unsaturated fats They contain adequate levels of minerals and vitamins and significant amounts of other bioactive components such as saponins phytosterols squalene fagopyritols and polyphenols

Functional food components ndash micronutrients

httpquinuapewp-contentuploads201302antiox-Gallagherpdf

Seven-step process would ensure that functional foods are safe and effective with health claims that are accurate and regulatory oversight that is science based and efficient

Functional foods

FERGUS CLYDESDALE 2004 Functional Foods Opportunities amp Challenges Food Technology December 2004 Volume 58 No12

httpwwwgooglecompatentsUS20100196569

httpwwwgooglecompatentsWO2006048158A1cl=en

httpswwwgooglecompatentsUS6428824pg=PA2ampdq=Lepidium+peruvianumamphl=enampsa=Xampei=KxK2UanpKvOu4AOehICgDwampved=0CDoQ6AEwATgK

httpswwwgooglecompatentsUS7005148pg=PA3ampdq=vaccinium+corymbosumamphl=enampsa=Xampei=-xK2UZ7vF_a64AO0soG4Cgampsqi=2amppjf=1ampved=0CGwQ6AEwCA

httpswwwgooglecompatentsWO2001045648A2cl=enampdq=vaccinium+corymbosumamphl=enampsa=Xampei=9BO2Uc_5A9Sz4AOrsIEIampved=0CDQQ6AEwAA

Potential for future researchhellip

Top health issues consumers are concerned about preventing From NMI(2005)

A ELIZABETH SLOAN 2006 Top 10 Functional Food Trends Food Technology Volume 60 No 4

Enzymes ndash antimicrobials

httpwwwnaturecomsrep2013130402srep01584fullsrep01584html

Ply500 is an isolated cell lytic enzyme with peptidase activity against certain L monocytogenes serotypes

Phages on the surface of an Escherichia coli cell Source Eye of ScienceScience

Enzymes ndash ELISA

ldquoAntigens from the sample are attached to a surface Then a further specific antibody is applied over the surface so it can bind to the antigen This antibody is linked to an enzyme and in the final step a substance containing the enzymes substrate is added The subsequent reaction produces a detectable signal most commonly a color change in the substraterdquo

httpthefutureofthingscomarticles37biopen-senses-biothreatshtml

Enzymes ndash for food processing

httpwwwnovasepcombiomoleculesfood-ingredientsApplicationssugar-and-sweeteners-productionasp

Amylase

ldquoAmylases in breadmaking break down complex sugars such as starch (found in flour) into simple sugars Yeast then feeds on these simple sugars and converts it into the waste products of alcohol and CO2 This imparts flavour and causes the bread to riserdquo

Amylase

Enzymes ndash for food processing

In traditional beer brewing malted barley is mixed with hot water to create a mash which is held at a given temperature to allow the amylases in the malted grain to convert the barleys starch into sugars Different temperatures optimize the activity of alpha or beta amylase resulting in different mixtures of fermentable and unfermentable sugars

Enzymes ndash for food processing

Enzymes ndash for food processing

Lactase

ldquoLactase produced commercially can be extracted both from yeasts such as Kluyveromyces fragilis and Kluyveromyces lactis and from fungi such as Aspergillus niger and Aspergillus oryzae Its primary commercial use is to break down lactose in milk to make it suitable for people with lactose intolerancerdquo wwwwikipediaorg

Enzymes ndash for food processing Protease

Calf rennet

Vegetable rennet Cynara cardunculus

Fermentation-produced chymosin Aspergillus niger var awamori GM

Enzymes ndash for food processing Protease

Papain

Meat is sprinkled with the powder and the enzymes help to break down the meat fibers

httpwwwenzymedevelopmentcomapplicationstenderizer

Use of Mucor miehei Lipase to Improve Functional Properties of Yolk-Contaminated Egg Whites Laura N Macherey Frank D Conforti William Eigel III Sean F OrsquoKeefe Journal of Food Science Volume 76 Issue 4 pages C651ndashC655 May 2011

Enzymes ndash for food processing

Lipase

Microorganisms ndash ingredients production

ldquoCorynebacterium glutamicum was discovered in the 1950s in Japan as natural producer of glutamic acid It is now produced by direct fermentation used for industrial production of amino acids which are used as flavour enhancers in foodrdquo

Glutamic acid amp Lysine

httpbacmapwishartlabcomorganisms485

Microorganisms ndash ingredients production

Citric acid

ldquoCultures of A niger are fed on a sucrose or glucose-containing medium to produce citric acid The source of sugar is corn steep liquor molasses hydrolyzed corn starch or other inexpensive sugary solutionsrdquo

httpgenomejgi-psforgAspni5Aspni5homehtml

Microorganisms ndash ingredients production

Bacillus subtilis has been genetically modified to both increase the bacterias production of riboflavin and to introduce an antibiotic (ampicillin) resistance marker wwwwikipediaorg

Riboflavin (Vitamin B2)

httpwwwocrawdogcomcat-chickenhtm

Colored scanning electron micrographs of representative cheese starter (A-C) and nonstarter (D-F) lactic acid bacteria (LAB) Lactobacillus helveticus (A) Lb delbrueckii subsp bulgaricus (B) Lactococcus lactis (C) Lb casei (D) Pediococcus pentosaceus (E) and Lb brevis (F)

Cheese

Microorganisms ndash fermented products

Microorganisms ndash fermented products

McSweeney P(2004) Biochemistry of cheese ripening Vol 57 (2-3) Int J Dairy Technol

Cheese_ Emmental

Microorganisms ndash fermented products

ldquoIn the late stage of cheese production P freudenreichii consumes the lactic acid excreted by the other bacteria and releases carbon dioxide gas which slowly forms the bubbles that make holesrdquo wwwwikipediaorg

Streptococcus thermophilus Lactobacillus debrueckii helveticus and Propionibacterium freudenreichii

Cheese_ Gouda

Microorganisms ndash fermented products

Lactococcus lactis ssp cremoris lactis Leuconostoc mesenteroides ssp cremoris

Leuconostoc mesenteroides ssp cremoris are starter cultures used for flavor and aroma development through the production of diacetyl from citrate

Roquefort

Microorganisms ndash fermented products

Camembert

ldquoPenicillium roqueforti and Penicillium caseicolum possess very potent proteolytic systems The molds secrete acid and neutral metalloproteinases and several aminopeptidases and carboxypeptidases The mycelia also contain intracellular proteinases and peptidases that are probably released when the mould dies and lysesrdquo

Microorganisms ndash fermented products

Fermented milks

Microorganisms ndash fermented products

Fermented milks

ldquoKefir grains are a combination of bacteria and yeasts in a matrix of proteins lipids and sugars and this symbiotic matrix forms grains that resemble cauliflower For this reason a complex and highly variable community of lactic acid bacteria and yeasts can be found in these grainsrdquo wwwwikipediaorg

Genus Lactobacillus Leuconostoc Pediococcus Streptococcus Bifidobacerium

Microorganisms ndash fermented products Fermented meats

Hutkins Robert W Microbiology and Technology of Fermented Foods

Pediococcus pentosaceus

httpbiowebusueduemlabcurrent20newshtml

Microorganisms ndash fermented products

Meat cultures

Lactobacillus sakei 10000-times magnified (Bild Joumlrg Groth Blessing Biotech GmbH)

Lactobacillus curvatus Lactobacillus plantarum Lactobacillus pentosus Streptococcus carnosus Micrococcus varians

httpwwwwzwtumdeindexphpid=185ampL=1amptx_ttnews5Btt_news5D=280

Microorganisms ndash fermented products

Meat cultures

httpwwwchr-hansencomproductsproduct-areasmeat-cultureshtml

Microorganisms ndash fermented products

Salami

ldquoPenicillium nalgiovense P chrysogenum and P camenberti used as starters The mold is desired as it imparts flavor helps the drying process prevents spoilage (mainly preventing growth of other mycotoxin-producing moulds during the curing process) and give a typical white color on the surfacerdquo

Microorganisms ndash fermented products

Wine amp Beer

Microorganisms ndash fermented products

Wine amp Beer

ldquoDuring fermentation the yeast converts the sugar in the wort to alcohol and carbon dioxide in addition to small amounts of glycerol and acetic acidrdquo

Yeast of the species Saccharomyces cerevisiae

httpenwikipediaorgwikiYeast

Microorganisms ndash other fermented products

httpwwwpsmicrographscoukrhizopus-mould--rhizopus-oligosporus-science-image80012871

Tempeh

Tempeh is manufactured from soaked boiled and dired soybeans that are inoculated with mold spores of species of Rhizopus (R stolonifer R oryzae R oigosporus or R arrhizus) The mash is packed or rolled in banana leaves and then incubated until there is good growth of mycelium but little sporulation Machve KK Fermentation Technology 2009

Functional food components

Critical Reviews in Food Science and Nutrition Structural Design Principles for Delivery of Bioactive Components in Nutraceuticals and Functional Foods 2011 McClements J Andrew E Yeonhwa D amp Weiss J

BioBest Omega 3 probiotic yogurt is a source of omega-3 PUFA that are considered an important part of a healthy diet It also contains over 1 billion active probiotic cultures Lactobacillus acidophilus NCFM Bifidobacterium lactis Bi-07 per serving that contribute to healthy digestive tract flora httpwwwastrocaproductsbiobest_omega_3_12x100g_multipackUbJJb_nVA8s

Functional food components ndash Omega 3

Inhibition of β-carotene degradation in oil-in-water nanoemulsions Influence of oil-soluble and water-soluble antioxidants Cheng Qian Eric Andrew Decker Hang Xiao David Julian McClements Volume 135 Issue 3 1 December 2012 Pages 1036ndash1043

Functional food components ndash Carotenoids

β-carotene enriched oil-in-water nanoemulsions stabilized by different emulsifiers with either no antioxidants (control) or antioxidants (80 μM EDTA + 10000 ppm vitamin E acetate)

Functional food components ndash Polyphenols

Pomegranate Phenolics from the Peels Arils and Flowers Are Antiatherogenic Studies in Vivo in Atherosclerotic Apolipoprotein E-Deficient (E0) Mice and in Vitro in Cultured Macrophages and Lipoproteins J Agric Food Chem 2008 56 (3) pp 1148ndash1157

Pomegranate phenolics and mainly oligomers punicalagin punicalin and gallic and ellagic acids are major contributors to the beneficial effects of pomegranate juice

Functional food components ndash Antioxidant activity

J Med Food 2012 Nov15(11)968-73 doi 101089jmf20122282 Epub 2012 Oct 12 Prickly pear cactus (Opuntia ficus indica var saboten) protects against stress-induced acute gastric lesions in rats (maltodextrin y betanin)

httpcancerpreventionresearchaacrjournalsorgcontentearly200906191940-6207CAPR-08-0167abstract

Tea Polyphenols Decrease Serum Levels of Prostate-Specific Antigen Hepatocyte Growth Factor and Vascular Endothelial Growth Factor in Prostate Cancer Patients and Inhibit Production of Hepatocyte Growth Factor and Vascular Endothelial Growth Factor In vitro 2008 Jerry McLarty Rebecca LH Bigelow Mylinh Smith Don Elmajian Murali Ankem James A Cardelli

Functional food components ndash Polyphenols

ldquoNano-sized self assembled structured liquids = nanodrops Liquid carriers that pass through the digestive system effectively without sinking or breaking up to the absorption site These nanodrops carry the phytosterols to the large micelles that the body produces from the bile acid where they compete with cholesterol for entry into the micelle The phytosterols enter the micelle thereby inhibiting transportation of cholesterol from the digestive system into the bloodstreamrdquo Shemen Industries

Functional food components ndash Phytosterols

Goacutemez-Guilleacuten M C B Gimeacutenez et al (2011) Functional and bioactive properties of collagen and gelatin from alternative sources A review Food Hydrocolloids 25(8) 1813-1827

Functional food components ndash Bioactive peptides

httpwwwnuritascomscreening-mining-food-for-bioactive-peptides

Health and nutrition benefits associated with Fibregum its fermentation in the large bowel increases levels of beneficial bacteria which stimulates the production of short-chain fatty acids (SCFAs) that have such properties as lowering serum cholesterol it is a strong prebiotic helping to balance the intestinal microbial ecosystem in the distal colon

Functional food components ndash Prebiotic fiber

httpwwwnexiracomFibregumE284A2-healthy-prebiotic-fiber_6html

Senegalia senegal (acacia)

Functional food components ndash Essential minerals (Fe Zn Ca Se)

httpwwwfdagovFoodGuidanceRegulationGuidanceDocumentsRegulatoryInformationLabelingNutritionucm152626htm

Pseudocereals are considered an important energy source due to their starch content they also provide good quality protein dietary fibre and lipids rich in unsaturated fats They contain adequate levels of minerals and vitamins and significant amounts of other bioactive components such as saponins phytosterols squalene fagopyritols and polyphenols

Functional food components ndash micronutrients

httpquinuapewp-contentuploads201302antiox-Gallagherpdf

Seven-step process would ensure that functional foods are safe and effective with health claims that are accurate and regulatory oversight that is science based and efficient

Functional foods

FERGUS CLYDESDALE 2004 Functional Foods Opportunities amp Challenges Food Technology December 2004 Volume 58 No12

httpwwwgooglecompatentsUS20100196569

httpwwwgooglecompatentsWO2006048158A1cl=en

httpswwwgooglecompatentsUS6428824pg=PA2ampdq=Lepidium+peruvianumamphl=enampsa=Xampei=KxK2UanpKvOu4AOehICgDwampved=0CDoQ6AEwATgK

httpswwwgooglecompatentsUS7005148pg=PA3ampdq=vaccinium+corymbosumamphl=enampsa=Xampei=-xK2UZ7vF_a64AO0soG4Cgampsqi=2amppjf=1ampved=0CGwQ6AEwCA

httpswwwgooglecompatentsWO2001045648A2cl=enampdq=vaccinium+corymbosumamphl=enampsa=Xampei=9BO2Uc_5A9Sz4AOrsIEIampved=0CDQQ6AEwAA

Potential for future researchhellip

Top health issues consumers are concerned about preventing From NMI(2005)

A ELIZABETH SLOAN 2006 Top 10 Functional Food Trends Food Technology Volume 60 No 4

Enzymes ndash ELISA

ldquoAntigens from the sample are attached to a surface Then a further specific antibody is applied over the surface so it can bind to the antigen This antibody is linked to an enzyme and in the final step a substance containing the enzymes substrate is added The subsequent reaction produces a detectable signal most commonly a color change in the substraterdquo

httpthefutureofthingscomarticles37biopen-senses-biothreatshtml

Enzymes ndash for food processing

httpwwwnovasepcombiomoleculesfood-ingredientsApplicationssugar-and-sweeteners-productionasp

Amylase

ldquoAmylases in breadmaking break down complex sugars such as starch (found in flour) into simple sugars Yeast then feeds on these simple sugars and converts it into the waste products of alcohol and CO2 This imparts flavour and causes the bread to riserdquo

Amylase

Enzymes ndash for food processing

In traditional beer brewing malted barley is mixed with hot water to create a mash which is held at a given temperature to allow the amylases in the malted grain to convert the barleys starch into sugars Different temperatures optimize the activity of alpha or beta amylase resulting in different mixtures of fermentable and unfermentable sugars

Enzymes ndash for food processing

Enzymes ndash for food processing

Lactase

ldquoLactase produced commercially can be extracted both from yeasts such as Kluyveromyces fragilis and Kluyveromyces lactis and from fungi such as Aspergillus niger and Aspergillus oryzae Its primary commercial use is to break down lactose in milk to make it suitable for people with lactose intolerancerdquo wwwwikipediaorg

Enzymes ndash for food processing Protease

Calf rennet

Vegetable rennet Cynara cardunculus

Fermentation-produced chymosin Aspergillus niger var awamori GM

Enzymes ndash for food processing Protease

Papain

Meat is sprinkled with the powder and the enzymes help to break down the meat fibers

httpwwwenzymedevelopmentcomapplicationstenderizer

Use of Mucor miehei Lipase to Improve Functional Properties of Yolk-Contaminated Egg Whites Laura N Macherey Frank D Conforti William Eigel III Sean F OrsquoKeefe Journal of Food Science Volume 76 Issue 4 pages C651ndashC655 May 2011

Enzymes ndash for food processing

Lipase

Microorganisms ndash ingredients production

ldquoCorynebacterium glutamicum was discovered in the 1950s in Japan as natural producer of glutamic acid It is now produced by direct fermentation used for industrial production of amino acids which are used as flavour enhancers in foodrdquo

Glutamic acid amp Lysine

httpbacmapwishartlabcomorganisms485

Microorganisms ndash ingredients production

Citric acid

ldquoCultures of A niger are fed on a sucrose or glucose-containing medium to produce citric acid The source of sugar is corn steep liquor molasses hydrolyzed corn starch or other inexpensive sugary solutionsrdquo

httpgenomejgi-psforgAspni5Aspni5homehtml

Microorganisms ndash ingredients production

Bacillus subtilis has been genetically modified to both increase the bacterias production of riboflavin and to introduce an antibiotic (ampicillin) resistance marker wwwwikipediaorg

Riboflavin (Vitamin B2)

httpwwwocrawdogcomcat-chickenhtm

Colored scanning electron micrographs of representative cheese starter (A-C) and nonstarter (D-F) lactic acid bacteria (LAB) Lactobacillus helveticus (A) Lb delbrueckii subsp bulgaricus (B) Lactococcus lactis (C) Lb casei (D) Pediococcus pentosaceus (E) and Lb brevis (F)

Cheese

Microorganisms ndash fermented products

Microorganisms ndash fermented products

McSweeney P(2004) Biochemistry of cheese ripening Vol 57 (2-3) Int J Dairy Technol

Cheese_ Emmental

Microorganisms ndash fermented products

ldquoIn the late stage of cheese production P freudenreichii consumes the lactic acid excreted by the other bacteria and releases carbon dioxide gas which slowly forms the bubbles that make holesrdquo wwwwikipediaorg

Streptococcus thermophilus Lactobacillus debrueckii helveticus and Propionibacterium freudenreichii

Cheese_ Gouda

Microorganisms ndash fermented products

Lactococcus lactis ssp cremoris lactis Leuconostoc mesenteroides ssp cremoris

Leuconostoc mesenteroides ssp cremoris are starter cultures used for flavor and aroma development through the production of diacetyl from citrate

Roquefort

Microorganisms ndash fermented products

Camembert

ldquoPenicillium roqueforti and Penicillium caseicolum possess very potent proteolytic systems The molds secrete acid and neutral metalloproteinases and several aminopeptidases and carboxypeptidases The mycelia also contain intracellular proteinases and peptidases that are probably released when the mould dies and lysesrdquo

Microorganisms ndash fermented products

Fermented milks

Microorganisms ndash fermented products

Fermented milks

ldquoKefir grains are a combination of bacteria and yeasts in a matrix of proteins lipids and sugars and this symbiotic matrix forms grains that resemble cauliflower For this reason a complex and highly variable community of lactic acid bacteria and yeasts can be found in these grainsrdquo wwwwikipediaorg

Genus Lactobacillus Leuconostoc Pediococcus Streptococcus Bifidobacerium

Microorganisms ndash fermented products Fermented meats

Hutkins Robert W Microbiology and Technology of Fermented Foods

Pediococcus pentosaceus

httpbiowebusueduemlabcurrent20newshtml

Microorganisms ndash fermented products

Meat cultures

Lactobacillus sakei 10000-times magnified (Bild Joumlrg Groth Blessing Biotech GmbH)

Lactobacillus curvatus Lactobacillus plantarum Lactobacillus pentosus Streptococcus carnosus Micrococcus varians

httpwwwwzwtumdeindexphpid=185ampL=1amptx_ttnews5Btt_news5D=280

Microorganisms ndash fermented products

Meat cultures

httpwwwchr-hansencomproductsproduct-areasmeat-cultureshtml

Microorganisms ndash fermented products

Salami

ldquoPenicillium nalgiovense P chrysogenum and P camenberti used as starters The mold is desired as it imparts flavor helps the drying process prevents spoilage (mainly preventing growth of other mycotoxin-producing moulds during the curing process) and give a typical white color on the surfacerdquo

Microorganisms ndash fermented products

Wine amp Beer

Microorganisms ndash fermented products

Wine amp Beer

ldquoDuring fermentation the yeast converts the sugar in the wort to alcohol and carbon dioxide in addition to small amounts of glycerol and acetic acidrdquo

Yeast of the species Saccharomyces cerevisiae

httpenwikipediaorgwikiYeast

Microorganisms ndash other fermented products

httpwwwpsmicrographscoukrhizopus-mould--rhizopus-oligosporus-science-image80012871

Tempeh

Tempeh is manufactured from soaked boiled and dired soybeans that are inoculated with mold spores of species of Rhizopus (R stolonifer R oryzae R oigosporus or R arrhizus) The mash is packed or rolled in banana leaves and then incubated until there is good growth of mycelium but little sporulation Machve KK Fermentation Technology 2009

Functional food components

Critical Reviews in Food Science and Nutrition Structural Design Principles for Delivery of Bioactive Components in Nutraceuticals and Functional Foods 2011 McClements J Andrew E Yeonhwa D amp Weiss J

BioBest Omega 3 probiotic yogurt is a source of omega-3 PUFA that are considered an important part of a healthy diet It also contains over 1 billion active probiotic cultures Lactobacillus acidophilus NCFM Bifidobacterium lactis Bi-07 per serving that contribute to healthy digestive tract flora httpwwwastrocaproductsbiobest_omega_3_12x100g_multipackUbJJb_nVA8s

Functional food components ndash Omega 3

Inhibition of β-carotene degradation in oil-in-water nanoemulsions Influence of oil-soluble and water-soluble antioxidants Cheng Qian Eric Andrew Decker Hang Xiao David Julian McClements Volume 135 Issue 3 1 December 2012 Pages 1036ndash1043

Functional food components ndash Carotenoids

β-carotene enriched oil-in-water nanoemulsions stabilized by different emulsifiers with either no antioxidants (control) or antioxidants (80 μM EDTA + 10000 ppm vitamin E acetate)

Functional food components ndash Polyphenols

Pomegranate Phenolics from the Peels Arils and Flowers Are Antiatherogenic Studies in Vivo in Atherosclerotic Apolipoprotein E-Deficient (E0) Mice and in Vitro in Cultured Macrophages and Lipoproteins J Agric Food Chem 2008 56 (3) pp 1148ndash1157

Pomegranate phenolics and mainly oligomers punicalagin punicalin and gallic and ellagic acids are major contributors to the beneficial effects of pomegranate juice

Functional food components ndash Antioxidant activity

J Med Food 2012 Nov15(11)968-73 doi 101089jmf20122282 Epub 2012 Oct 12 Prickly pear cactus (Opuntia ficus indica var saboten) protects against stress-induced acute gastric lesions in rats (maltodextrin y betanin)

httpcancerpreventionresearchaacrjournalsorgcontentearly200906191940-6207CAPR-08-0167abstract

Tea Polyphenols Decrease Serum Levels of Prostate-Specific Antigen Hepatocyte Growth Factor and Vascular Endothelial Growth Factor in Prostate Cancer Patients and Inhibit Production of Hepatocyte Growth Factor and Vascular Endothelial Growth Factor In vitro 2008 Jerry McLarty Rebecca LH Bigelow Mylinh Smith Don Elmajian Murali Ankem James A Cardelli

Functional food components ndash Polyphenols

ldquoNano-sized self assembled structured liquids = nanodrops Liquid carriers that pass through the digestive system effectively without sinking or breaking up to the absorption site These nanodrops carry the phytosterols to the large micelles that the body produces from the bile acid where they compete with cholesterol for entry into the micelle The phytosterols enter the micelle thereby inhibiting transportation of cholesterol from the digestive system into the bloodstreamrdquo Shemen Industries

Functional food components ndash Phytosterols

Goacutemez-Guilleacuten M C B Gimeacutenez et al (2011) Functional and bioactive properties of collagen and gelatin from alternative sources A review Food Hydrocolloids 25(8) 1813-1827

Functional food components ndash Bioactive peptides

httpwwwnuritascomscreening-mining-food-for-bioactive-peptides

Health and nutrition benefits associated with Fibregum its fermentation in the large bowel increases levels of beneficial bacteria which stimulates the production of short-chain fatty acids (SCFAs) that have such properties as lowering serum cholesterol it is a strong prebiotic helping to balance the intestinal microbial ecosystem in the distal colon

Functional food components ndash Prebiotic fiber

httpwwwnexiracomFibregumE284A2-healthy-prebiotic-fiber_6html

Senegalia senegal (acacia)

Functional food components ndash Essential minerals (Fe Zn Ca Se)

httpwwwfdagovFoodGuidanceRegulationGuidanceDocumentsRegulatoryInformationLabelingNutritionucm152626htm

Pseudocereals are considered an important energy source due to their starch content they also provide good quality protein dietary fibre and lipids rich in unsaturated fats They contain adequate levels of minerals and vitamins and significant amounts of other bioactive components such as saponins phytosterols squalene fagopyritols and polyphenols

Functional food components ndash micronutrients

httpquinuapewp-contentuploads201302antiox-Gallagherpdf

Seven-step process would ensure that functional foods are safe and effective with health claims that are accurate and regulatory oversight that is science based and efficient

Functional foods

FERGUS CLYDESDALE 2004 Functional Foods Opportunities amp Challenges Food Technology December 2004 Volume 58 No12

httpwwwgooglecompatentsUS20100196569

httpwwwgooglecompatentsWO2006048158A1cl=en

httpswwwgooglecompatentsUS6428824pg=PA2ampdq=Lepidium+peruvianumamphl=enampsa=Xampei=KxK2UanpKvOu4AOehICgDwampved=0CDoQ6AEwATgK

httpswwwgooglecompatentsUS7005148pg=PA3ampdq=vaccinium+corymbosumamphl=enampsa=Xampei=-xK2UZ7vF_a64AO0soG4Cgampsqi=2amppjf=1ampved=0CGwQ6AEwCA

httpswwwgooglecompatentsWO2001045648A2cl=enampdq=vaccinium+corymbosumamphl=enampsa=Xampei=9BO2Uc_5A9Sz4AOrsIEIampved=0CDQQ6AEwAA

Potential for future researchhellip

Top health issues consumers are concerned about preventing From NMI(2005)

A ELIZABETH SLOAN 2006 Top 10 Functional Food Trends Food Technology Volume 60 No 4

Enzymes ndash for food processing

httpwwwnovasepcombiomoleculesfood-ingredientsApplicationssugar-and-sweeteners-productionasp

Amylase

ldquoAmylases in breadmaking break down complex sugars such as starch (found in flour) into simple sugars Yeast then feeds on these simple sugars and converts it into the waste products of alcohol and CO2 This imparts flavour and causes the bread to riserdquo

Amylase

Enzymes ndash for food processing

In traditional beer brewing malted barley is mixed with hot water to create a mash which is held at a given temperature to allow the amylases in the malted grain to convert the barleys starch into sugars Different temperatures optimize the activity of alpha or beta amylase resulting in different mixtures of fermentable and unfermentable sugars

Enzymes ndash for food processing

Enzymes ndash for food processing

Lactase

ldquoLactase produced commercially can be extracted both from yeasts such as Kluyveromyces fragilis and Kluyveromyces lactis and from fungi such as Aspergillus niger and Aspergillus oryzae Its primary commercial use is to break down lactose in milk to make it suitable for people with lactose intolerancerdquo wwwwikipediaorg

Enzymes ndash for food processing Protease

Calf rennet

Vegetable rennet Cynara cardunculus

Fermentation-produced chymosin Aspergillus niger var awamori GM

Enzymes ndash for food processing Protease

Papain

Meat is sprinkled with the powder and the enzymes help to break down the meat fibers

httpwwwenzymedevelopmentcomapplicationstenderizer

Use of Mucor miehei Lipase to Improve Functional Properties of Yolk-Contaminated Egg Whites Laura N Macherey Frank D Conforti William Eigel III Sean F OrsquoKeefe Journal of Food Science Volume 76 Issue 4 pages C651ndashC655 May 2011

Enzymes ndash for food processing

Lipase

Microorganisms ndash ingredients production

ldquoCorynebacterium glutamicum was discovered in the 1950s in Japan as natural producer of glutamic acid It is now produced by direct fermentation used for industrial production of amino acids which are used as flavour enhancers in foodrdquo

Glutamic acid amp Lysine

httpbacmapwishartlabcomorganisms485

Microorganisms ndash ingredients production

Citric acid

ldquoCultures of A niger are fed on a sucrose or glucose-containing medium to produce citric acid The source of sugar is corn steep liquor molasses hydrolyzed corn starch or other inexpensive sugary solutionsrdquo

httpgenomejgi-psforgAspni5Aspni5homehtml

Microorganisms ndash ingredients production

Bacillus subtilis has been genetically modified to both increase the bacterias production of riboflavin and to introduce an antibiotic (ampicillin) resistance marker wwwwikipediaorg

Riboflavin (Vitamin B2)

httpwwwocrawdogcomcat-chickenhtm

Colored scanning electron micrographs of representative cheese starter (A-C) and nonstarter (D-F) lactic acid bacteria (LAB) Lactobacillus helveticus (A) Lb delbrueckii subsp bulgaricus (B) Lactococcus lactis (C) Lb casei (D) Pediococcus pentosaceus (E) and Lb brevis (F)

Cheese

Microorganisms ndash fermented products

Microorganisms ndash fermented products

McSweeney P(2004) Biochemistry of cheese ripening Vol 57 (2-3) Int J Dairy Technol

Cheese_ Emmental

Microorganisms ndash fermented products

ldquoIn the late stage of cheese production P freudenreichii consumes the lactic acid excreted by the other bacteria and releases carbon dioxide gas which slowly forms the bubbles that make holesrdquo wwwwikipediaorg

Streptococcus thermophilus Lactobacillus debrueckii helveticus and Propionibacterium freudenreichii

Cheese_ Gouda

Microorganisms ndash fermented products

Lactococcus lactis ssp cremoris lactis Leuconostoc mesenteroides ssp cremoris

Leuconostoc mesenteroides ssp cremoris are starter cultures used for flavor and aroma development through the production of diacetyl from citrate

Roquefort

Microorganisms ndash fermented products

Camembert

ldquoPenicillium roqueforti and Penicillium caseicolum possess very potent proteolytic systems The molds secrete acid and neutral metalloproteinases and several aminopeptidases and carboxypeptidases The mycelia also contain intracellular proteinases and peptidases that are probably released when the mould dies and lysesrdquo

Microorganisms ndash fermented products

Fermented milks

Microorganisms ndash fermented products

Fermented milks

ldquoKefir grains are a combination of bacteria and yeasts in a matrix of proteins lipids and sugars and this symbiotic matrix forms grains that resemble cauliflower For this reason a complex and highly variable community of lactic acid bacteria and yeasts can be found in these grainsrdquo wwwwikipediaorg

Genus Lactobacillus Leuconostoc Pediococcus Streptococcus Bifidobacerium

Microorganisms ndash fermented products Fermented meats

Hutkins Robert W Microbiology and Technology of Fermented Foods

Pediococcus pentosaceus

httpbiowebusueduemlabcurrent20newshtml

Microorganisms ndash fermented products

Meat cultures

Lactobacillus sakei 10000-times magnified (Bild Joumlrg Groth Blessing Biotech GmbH)

Lactobacillus curvatus Lactobacillus plantarum Lactobacillus pentosus Streptococcus carnosus Micrococcus varians

httpwwwwzwtumdeindexphpid=185ampL=1amptx_ttnews5Btt_news5D=280

Microorganisms ndash fermented products

Meat cultures

httpwwwchr-hansencomproductsproduct-areasmeat-cultureshtml

Microorganisms ndash fermented products

Salami

ldquoPenicillium nalgiovense P chrysogenum and P camenberti used as starters The mold is desired as it imparts flavor helps the drying process prevents spoilage (mainly preventing growth of other mycotoxin-producing moulds during the curing process) and give a typical white color on the surfacerdquo

Microorganisms ndash fermented products

Wine amp Beer

Microorganisms ndash fermented products

Wine amp Beer

ldquoDuring fermentation the yeast converts the sugar in the wort to alcohol and carbon dioxide in addition to small amounts of glycerol and acetic acidrdquo

Yeast of the species Saccharomyces cerevisiae

httpenwikipediaorgwikiYeast

Microorganisms ndash other fermented products

httpwwwpsmicrographscoukrhizopus-mould--rhizopus-oligosporus-science-image80012871

Tempeh

Tempeh is manufactured from soaked boiled and dired soybeans that are inoculated with mold spores of species of Rhizopus (R stolonifer R oryzae R oigosporus or R arrhizus) The mash is packed or rolled in banana leaves and then incubated until there is good growth of mycelium but little sporulation Machve KK Fermentation Technology 2009

Functional food components

Critical Reviews in Food Science and Nutrition Structural Design Principles for Delivery of Bioactive Components in Nutraceuticals and Functional Foods 2011 McClements J Andrew E Yeonhwa D amp Weiss J

BioBest Omega 3 probiotic yogurt is a source of omega-3 PUFA that are considered an important part of a healthy diet It also contains over 1 billion active probiotic cultures Lactobacillus acidophilus NCFM Bifidobacterium lactis Bi-07 per serving that contribute to healthy digestive tract flora httpwwwastrocaproductsbiobest_omega_3_12x100g_multipackUbJJb_nVA8s

Functional food components ndash Omega 3

Inhibition of β-carotene degradation in oil-in-water nanoemulsions Influence of oil-soluble and water-soluble antioxidants Cheng Qian Eric Andrew Decker Hang Xiao David Julian McClements Volume 135 Issue 3 1 December 2012 Pages 1036ndash1043

Functional food components ndash Carotenoids

β-carotene enriched oil-in-water nanoemulsions stabilized by different emulsifiers with either no antioxidants (control) or antioxidants (80 μM EDTA + 10000 ppm vitamin E acetate)

Functional food components ndash Polyphenols

Pomegranate Phenolics from the Peels Arils and Flowers Are Antiatherogenic Studies in Vivo in Atherosclerotic Apolipoprotein E-Deficient (E0) Mice and in Vitro in Cultured Macrophages and Lipoproteins J Agric Food Chem 2008 56 (3) pp 1148ndash1157

Pomegranate phenolics and mainly oligomers punicalagin punicalin and gallic and ellagic acids are major contributors to the beneficial effects of pomegranate juice

Functional food components ndash Antioxidant activity

J Med Food 2012 Nov15(11)968-73 doi 101089jmf20122282 Epub 2012 Oct 12 Prickly pear cactus (Opuntia ficus indica var saboten) protects against stress-induced acute gastric lesions in rats (maltodextrin y betanin)

httpcancerpreventionresearchaacrjournalsorgcontentearly200906191940-6207CAPR-08-0167abstract

Tea Polyphenols Decrease Serum Levels of Prostate-Specific Antigen Hepatocyte Growth Factor and Vascular Endothelial Growth Factor in Prostate Cancer Patients and Inhibit Production of Hepatocyte Growth Factor and Vascular Endothelial Growth Factor In vitro 2008 Jerry McLarty Rebecca LH Bigelow Mylinh Smith Don Elmajian Murali Ankem James A Cardelli

Functional food components ndash Polyphenols

ldquoNano-sized self assembled structured liquids = nanodrops Liquid carriers that pass through the digestive system effectively without sinking or breaking up to the absorption site These nanodrops carry the phytosterols to the large micelles that the body produces from the bile acid where they compete with cholesterol for entry into the micelle The phytosterols enter the micelle thereby inhibiting transportation of cholesterol from the digestive system into the bloodstreamrdquo Shemen Industries

Functional food components ndash Phytosterols

Goacutemez-Guilleacuten M C B Gimeacutenez et al (2011) Functional and bioactive properties of collagen and gelatin from alternative sources A review Food Hydrocolloids 25(8) 1813-1827

Functional food components ndash Bioactive peptides

httpwwwnuritascomscreening-mining-food-for-bioactive-peptides

Health and nutrition benefits associated with Fibregum its fermentation in the large bowel increases levels of beneficial bacteria which stimulates the production of short-chain fatty acids (SCFAs) that have such properties as lowering serum cholesterol it is a strong prebiotic helping to balance the intestinal microbial ecosystem in the distal colon

Functional food components ndash Prebiotic fiber

httpwwwnexiracomFibregumE284A2-healthy-prebiotic-fiber_6html

Senegalia senegal (acacia)

Functional food components ndash Essential minerals (Fe Zn Ca Se)

httpwwwfdagovFoodGuidanceRegulationGuidanceDocumentsRegulatoryInformationLabelingNutritionucm152626htm

Pseudocereals are considered an important energy source due to their starch content they also provide good quality protein dietary fibre and lipids rich in unsaturated fats They contain adequate levels of minerals and vitamins and significant amounts of other bioactive components such as saponins phytosterols squalene fagopyritols and polyphenols

Functional food components ndash micronutrients

httpquinuapewp-contentuploads201302antiox-Gallagherpdf

Seven-step process would ensure that functional foods are safe and effective with health claims that are accurate and regulatory oversight that is science based and efficient

Functional foods

FERGUS CLYDESDALE 2004 Functional Foods Opportunities amp Challenges Food Technology December 2004 Volume 58 No12

httpwwwgooglecompatentsUS20100196569

httpwwwgooglecompatentsWO2006048158A1cl=en

httpswwwgooglecompatentsUS6428824pg=PA2ampdq=Lepidium+peruvianumamphl=enampsa=Xampei=KxK2UanpKvOu4AOehICgDwampved=0CDoQ6AEwATgK

httpswwwgooglecompatentsUS7005148pg=PA3ampdq=vaccinium+corymbosumamphl=enampsa=Xampei=-xK2UZ7vF_a64AO0soG4Cgampsqi=2amppjf=1ampved=0CGwQ6AEwCA

httpswwwgooglecompatentsWO2001045648A2cl=enampdq=vaccinium+corymbosumamphl=enampsa=Xampei=9BO2Uc_5A9Sz4AOrsIEIampved=0CDQQ6AEwAA

Potential for future researchhellip

Top health issues consumers are concerned about preventing From NMI(2005)

A ELIZABETH SLOAN 2006 Top 10 Functional Food Trends Food Technology Volume 60 No 4

ldquoAmylases in breadmaking break down complex sugars such as starch (found in flour) into simple sugars Yeast then feeds on these simple sugars and converts it into the waste products of alcohol and CO2 This imparts flavour and causes the bread to riserdquo

Amylase

Enzymes ndash for food processing

In traditional beer brewing malted barley is mixed with hot water to create a mash which is held at a given temperature to allow the amylases in the malted grain to convert the barleys starch into sugars Different temperatures optimize the activity of alpha or beta amylase resulting in different mixtures of fermentable and unfermentable sugars

Enzymes ndash for food processing

Enzymes ndash for food processing

Lactase

ldquoLactase produced commercially can be extracted both from yeasts such as Kluyveromyces fragilis and Kluyveromyces lactis and from fungi such as Aspergillus niger and Aspergillus oryzae Its primary commercial use is to break down lactose in milk to make it suitable for people with lactose intolerancerdquo wwwwikipediaorg

Enzymes ndash for food processing Protease

Calf rennet

Vegetable rennet Cynara cardunculus

Fermentation-produced chymosin Aspergillus niger var awamori GM

Enzymes ndash for food processing Protease

Papain

Meat is sprinkled with the powder and the enzymes help to break down the meat fibers

httpwwwenzymedevelopmentcomapplicationstenderizer

Use of Mucor miehei Lipase to Improve Functional Properties of Yolk-Contaminated Egg Whites Laura N Macherey Frank D Conforti William Eigel III Sean F OrsquoKeefe Journal of Food Science Volume 76 Issue 4 pages C651ndashC655 May 2011

Enzymes ndash for food processing

Lipase

Microorganisms ndash ingredients production

ldquoCorynebacterium glutamicum was discovered in the 1950s in Japan as natural producer of glutamic acid It is now produced by direct fermentation used for industrial production of amino acids which are used as flavour enhancers in foodrdquo

Glutamic acid amp Lysine

httpbacmapwishartlabcomorganisms485

Microorganisms ndash ingredients production

Citric acid

ldquoCultures of A niger are fed on a sucrose or glucose-containing medium to produce citric acid The source of sugar is corn steep liquor molasses hydrolyzed corn starch or other inexpensive sugary solutionsrdquo

httpgenomejgi-psforgAspni5Aspni5homehtml

Microorganisms ndash ingredients production

Bacillus subtilis has been genetically modified to both increase the bacterias production of riboflavin and to introduce an antibiotic (ampicillin) resistance marker wwwwikipediaorg

Riboflavin (Vitamin B2)

httpwwwocrawdogcomcat-chickenhtm

Colored scanning electron micrographs of representative cheese starter (A-C) and nonstarter (D-F) lactic acid bacteria (LAB) Lactobacillus helveticus (A) Lb delbrueckii subsp bulgaricus (B) Lactococcus lactis (C) Lb casei (D) Pediococcus pentosaceus (E) and Lb brevis (F)

Cheese

Microorganisms ndash fermented products

Microorganisms ndash fermented products

McSweeney P(2004) Biochemistry of cheese ripening Vol 57 (2-3) Int J Dairy Technol

Cheese_ Emmental

Microorganisms ndash fermented products

ldquoIn the late stage of cheese production P freudenreichii consumes the lactic acid excreted by the other bacteria and releases carbon dioxide gas which slowly forms the bubbles that make holesrdquo wwwwikipediaorg

Streptococcus thermophilus Lactobacillus debrueckii helveticus and Propionibacterium freudenreichii

Cheese_ Gouda

Microorganisms ndash fermented products

Lactococcus lactis ssp cremoris lactis Leuconostoc mesenteroides ssp cremoris

Leuconostoc mesenteroides ssp cremoris are starter cultures used for flavor and aroma development through the production of diacetyl from citrate

Roquefort

Microorganisms ndash fermented products

Camembert

ldquoPenicillium roqueforti and Penicillium caseicolum possess very potent proteolytic systems The molds secrete acid and neutral metalloproteinases and several aminopeptidases and carboxypeptidases The mycelia also contain intracellular proteinases and peptidases that are probably released when the mould dies and lysesrdquo

Microorganisms ndash fermented products

Fermented milks

Microorganisms ndash fermented products

Fermented milks

ldquoKefir grains are a combination of bacteria and yeasts in a matrix of proteins lipids and sugars and this symbiotic matrix forms grains that resemble cauliflower For this reason a complex and highly variable community of lactic acid bacteria and yeasts can be found in these grainsrdquo wwwwikipediaorg

Genus Lactobacillus Leuconostoc Pediococcus Streptococcus Bifidobacerium

Microorganisms ndash fermented products Fermented meats

Hutkins Robert W Microbiology and Technology of Fermented Foods

Pediococcus pentosaceus

httpbiowebusueduemlabcurrent20newshtml

Microorganisms ndash fermented products

Meat cultures

Lactobacillus sakei 10000-times magnified (Bild Joumlrg Groth Blessing Biotech GmbH)

Lactobacillus curvatus Lactobacillus plantarum Lactobacillus pentosus Streptococcus carnosus Micrococcus varians

httpwwwwzwtumdeindexphpid=185ampL=1amptx_ttnews5Btt_news5D=280

Microorganisms ndash fermented products

Meat cultures

httpwwwchr-hansencomproductsproduct-areasmeat-cultureshtml

Microorganisms ndash fermented products

Salami

ldquoPenicillium nalgiovense P chrysogenum and P camenberti used as starters The mold is desired as it imparts flavor helps the drying process prevents spoilage (mainly preventing growth of other mycotoxin-producing moulds during the curing process) and give a typical white color on the surfacerdquo

Microorganisms ndash fermented products

Wine amp Beer

Microorganisms ndash fermented products

Wine amp Beer

ldquoDuring fermentation the yeast converts the sugar in the wort to alcohol and carbon dioxide in addition to small amounts of glycerol and acetic acidrdquo

Yeast of the species Saccharomyces cerevisiae

httpenwikipediaorgwikiYeast

Microorganisms ndash other fermented products

httpwwwpsmicrographscoukrhizopus-mould--rhizopus-oligosporus-science-image80012871

Tempeh

Tempeh is manufactured from soaked boiled and dired soybeans that are inoculated with mold spores of species of Rhizopus (R stolonifer R oryzae R oigosporus or R arrhizus) The mash is packed or rolled in banana leaves and then incubated until there is good growth of mycelium but little sporulation Machve KK Fermentation Technology 2009

Functional food components

Critical Reviews in Food Science and Nutrition Structural Design Principles for Delivery of Bioactive Components in Nutraceuticals and Functional Foods 2011 McClements J Andrew E Yeonhwa D amp Weiss J

BioBest Omega 3 probiotic yogurt is a source of omega-3 PUFA that are considered an important part of a healthy diet It also contains over 1 billion active probiotic cultures Lactobacillus acidophilus NCFM Bifidobacterium lactis Bi-07 per serving that contribute to healthy digestive tract flora httpwwwastrocaproductsbiobest_omega_3_12x100g_multipackUbJJb_nVA8s

Functional food components ndash Omega 3

Inhibition of β-carotene degradation in oil-in-water nanoemulsions Influence of oil-soluble and water-soluble antioxidants Cheng Qian Eric Andrew Decker Hang Xiao David Julian McClements Volume 135 Issue 3 1 December 2012 Pages 1036ndash1043

Functional food components ndash Carotenoids

β-carotene enriched oil-in-water nanoemulsions stabilized by different emulsifiers with either no antioxidants (control) or antioxidants (80 μM EDTA + 10000 ppm vitamin E acetate)

Functional food components ndash Polyphenols

Pomegranate Phenolics from the Peels Arils and Flowers Are Antiatherogenic Studies in Vivo in Atherosclerotic Apolipoprotein E-Deficient (E0) Mice and in Vitro in Cultured Macrophages and Lipoproteins J Agric Food Chem 2008 56 (3) pp 1148ndash1157

Pomegranate phenolics and mainly oligomers punicalagin punicalin and gallic and ellagic acids are major contributors to the beneficial effects of pomegranate juice

Functional food components ndash Antioxidant activity

J Med Food 2012 Nov15(11)968-73 doi 101089jmf20122282 Epub 2012 Oct 12 Prickly pear cactus (Opuntia ficus indica var saboten) protects against stress-induced acute gastric lesions in rats (maltodextrin y betanin)

httpcancerpreventionresearchaacrjournalsorgcontentearly200906191940-6207CAPR-08-0167abstract

Tea Polyphenols Decrease Serum Levels of Prostate-Specific Antigen Hepatocyte Growth Factor and Vascular Endothelial Growth Factor in Prostate Cancer Patients and Inhibit Production of Hepatocyte Growth Factor and Vascular Endothelial Growth Factor In vitro 2008 Jerry McLarty Rebecca LH Bigelow Mylinh Smith Don Elmajian Murali Ankem James A Cardelli

Functional food components ndash Polyphenols

ldquoNano-sized self assembled structured liquids = nanodrops Liquid carriers that pass through the digestive system effectively without sinking or breaking up to the absorption site These nanodrops carry the phytosterols to the large micelles that the body produces from the bile acid where they compete with cholesterol for entry into the micelle The phytosterols enter the micelle thereby inhibiting transportation of cholesterol from the digestive system into the bloodstreamrdquo Shemen Industries

Functional food components ndash Phytosterols

Goacutemez-Guilleacuten M C B Gimeacutenez et al (2011) Functional and bioactive properties of collagen and gelatin from alternative sources A review Food Hydrocolloids 25(8) 1813-1827

Functional food components ndash Bioactive peptides

httpwwwnuritascomscreening-mining-food-for-bioactive-peptides

Health and nutrition benefits associated with Fibregum its fermentation in the large bowel increases levels of beneficial bacteria which stimulates the production of short-chain fatty acids (SCFAs) that have such properties as lowering serum cholesterol it is a strong prebiotic helping to balance the intestinal microbial ecosystem in the distal colon

Functional food components ndash Prebiotic fiber

httpwwwnexiracomFibregumE284A2-healthy-prebiotic-fiber_6html

Senegalia senegal (acacia)

Functional food components ndash Essential minerals (Fe Zn Ca Se)

httpwwwfdagovFoodGuidanceRegulationGuidanceDocumentsRegulatoryInformationLabelingNutritionucm152626htm

Pseudocereals are considered an important energy source due to their starch content they also provide good quality protein dietary fibre and lipids rich in unsaturated fats They contain adequate levels of minerals and vitamins and significant amounts of other bioactive components such as saponins phytosterols squalene fagopyritols and polyphenols

Functional food components ndash micronutrients

httpquinuapewp-contentuploads201302antiox-Gallagherpdf

Seven-step process would ensure that functional foods are safe and effective with health claims that are accurate and regulatory oversight that is science based and efficient

Functional foods

FERGUS CLYDESDALE 2004 Functional Foods Opportunities amp Challenges Food Technology December 2004 Volume 58 No12

httpwwwgooglecompatentsUS20100196569

httpwwwgooglecompatentsWO2006048158A1cl=en

httpswwwgooglecompatentsUS6428824pg=PA2ampdq=Lepidium+peruvianumamphl=enampsa=Xampei=KxK2UanpKvOu4AOehICgDwampved=0CDoQ6AEwATgK

httpswwwgooglecompatentsUS7005148pg=PA3ampdq=vaccinium+corymbosumamphl=enampsa=Xampei=-xK2UZ7vF_a64AO0soG4Cgampsqi=2amppjf=1ampved=0CGwQ6AEwCA

httpswwwgooglecompatentsWO2001045648A2cl=enampdq=vaccinium+corymbosumamphl=enampsa=Xampei=9BO2Uc_5A9Sz4AOrsIEIampved=0CDQQ6AEwAA

Potential for future researchhellip

Top health issues consumers are concerned about preventing From NMI(2005)

A ELIZABETH SLOAN 2006 Top 10 Functional Food Trends Food Technology Volume 60 No 4

In traditional beer brewing malted barley is mixed with hot water to create a mash which is held at a given temperature to allow the amylases in the malted grain to convert the barleys starch into sugars Different temperatures optimize the activity of alpha or beta amylase resulting in different mixtures of fermentable and unfermentable sugars

Enzymes ndash for food processing

Enzymes ndash for food processing

Lactase

ldquoLactase produced commercially can be extracted both from yeasts such as Kluyveromyces fragilis and Kluyveromyces lactis and from fungi such as Aspergillus niger and Aspergillus oryzae Its primary commercial use is to break down lactose in milk to make it suitable for people with lactose intolerancerdquo wwwwikipediaorg

Enzymes ndash for food processing Protease

Calf rennet

Vegetable rennet Cynara cardunculus

Fermentation-produced chymosin Aspergillus niger var awamori GM

Enzymes ndash for food processing Protease

Papain

Meat is sprinkled with the powder and the enzymes help to break down the meat fibers

httpwwwenzymedevelopmentcomapplicationstenderizer

Use of Mucor miehei Lipase to Improve Functional Properties of Yolk-Contaminated Egg Whites Laura N Macherey Frank D Conforti William Eigel III Sean F OrsquoKeefe Journal of Food Science Volume 76 Issue 4 pages C651ndashC655 May 2011

Enzymes ndash for food processing

Lipase

Microorganisms ndash ingredients production

ldquoCorynebacterium glutamicum was discovered in the 1950s in Japan as natural producer of glutamic acid It is now produced by direct fermentation used for industrial production of amino acids which are used as flavour enhancers in foodrdquo

Glutamic acid amp Lysine

httpbacmapwishartlabcomorganisms485

Microorganisms ndash ingredients production

Citric acid

ldquoCultures of A niger are fed on a sucrose or glucose-containing medium to produce citric acid The source of sugar is corn steep liquor molasses hydrolyzed corn starch or other inexpensive sugary solutionsrdquo

httpgenomejgi-psforgAspni5Aspni5homehtml

Microorganisms ndash ingredients production

Bacillus subtilis has been genetically modified to both increase the bacterias production of riboflavin and to introduce an antibiotic (ampicillin) resistance marker wwwwikipediaorg

Riboflavin (Vitamin B2)

httpwwwocrawdogcomcat-chickenhtm

Colored scanning electron micrographs of representative cheese starter (A-C) and nonstarter (D-F) lactic acid bacteria (LAB) Lactobacillus helveticus (A) Lb delbrueckii subsp bulgaricus (B) Lactococcus lactis (C) Lb casei (D) Pediococcus pentosaceus (E) and Lb brevis (F)

Cheese

Microorganisms ndash fermented products

Microorganisms ndash fermented products

McSweeney P(2004) Biochemistry of cheese ripening Vol 57 (2-3) Int J Dairy Technol

Cheese_ Emmental

Microorganisms ndash fermented products

ldquoIn the late stage of cheese production P freudenreichii consumes the lactic acid excreted by the other bacteria and releases carbon dioxide gas which slowly forms the bubbles that make holesrdquo wwwwikipediaorg

Streptococcus thermophilus Lactobacillus debrueckii helveticus and Propionibacterium freudenreichii

Cheese_ Gouda

Microorganisms ndash fermented products

Lactococcus lactis ssp cremoris lactis Leuconostoc mesenteroides ssp cremoris

Leuconostoc mesenteroides ssp cremoris are starter cultures used for flavor and aroma development through the production of diacetyl from citrate

Roquefort

Microorganisms ndash fermented products

Camembert

ldquoPenicillium roqueforti and Penicillium caseicolum possess very potent proteolytic systems The molds secrete acid and neutral metalloproteinases and several aminopeptidases and carboxypeptidases The mycelia also contain intracellular proteinases and peptidases that are probably released when the mould dies and lysesrdquo

Microorganisms ndash fermented products

Fermented milks

Microorganisms ndash fermented products

Fermented milks

ldquoKefir grains are a combination of bacteria and yeasts in a matrix of proteins lipids and sugars and this symbiotic matrix forms grains that resemble cauliflower For this reason a complex and highly variable community of lactic acid bacteria and yeasts can be found in these grainsrdquo wwwwikipediaorg

Genus Lactobacillus Leuconostoc Pediococcus Streptococcus Bifidobacerium

Microorganisms ndash fermented products Fermented meats

Hutkins Robert W Microbiology and Technology of Fermented Foods

Pediococcus pentosaceus

httpbiowebusueduemlabcurrent20newshtml

Microorganisms ndash fermented products

Meat cultures

Lactobacillus sakei 10000-times magnified (Bild Joumlrg Groth Blessing Biotech GmbH)

Lactobacillus curvatus Lactobacillus plantarum Lactobacillus pentosus Streptococcus carnosus Micrococcus varians

httpwwwwzwtumdeindexphpid=185ampL=1amptx_ttnews5Btt_news5D=280

Microorganisms ndash fermented products

Meat cultures

httpwwwchr-hansencomproductsproduct-areasmeat-cultureshtml

Microorganisms ndash fermented products

Salami

ldquoPenicillium nalgiovense P chrysogenum and P camenberti used as starters The mold is desired as it imparts flavor helps the drying process prevents spoilage (mainly preventing growth of other mycotoxin-producing moulds during the curing process) and give a typical white color on the surfacerdquo

Microorganisms ndash fermented products

Wine amp Beer

Microorganisms ndash fermented products

Wine amp Beer

ldquoDuring fermentation the yeast converts the sugar in the wort to alcohol and carbon dioxide in addition to small amounts of glycerol and acetic acidrdquo

Yeast of the species Saccharomyces cerevisiae

httpenwikipediaorgwikiYeast

Microorganisms ndash other fermented products

httpwwwpsmicrographscoukrhizopus-mould--rhizopus-oligosporus-science-image80012871

Tempeh

Tempeh is manufactured from soaked boiled and dired soybeans that are inoculated with mold spores of species of Rhizopus (R stolonifer R oryzae R oigosporus or R arrhizus) The mash is packed or rolled in banana leaves and then incubated until there is good growth of mycelium but little sporulation Machve KK Fermentation Technology 2009

Functional food components

Critical Reviews in Food Science and Nutrition Structural Design Principles for Delivery of Bioactive Components in Nutraceuticals and Functional Foods 2011 McClements J Andrew E Yeonhwa D amp Weiss J

BioBest Omega 3 probiotic yogurt is a source of omega-3 PUFA that are considered an important part of a healthy diet It also contains over 1 billion active probiotic cultures Lactobacillus acidophilus NCFM Bifidobacterium lactis Bi-07 per serving that contribute to healthy digestive tract flora httpwwwastrocaproductsbiobest_omega_3_12x100g_multipackUbJJb_nVA8s

Functional food components ndash Omega 3

Inhibition of β-carotene degradation in oil-in-water nanoemulsions Influence of oil-soluble and water-soluble antioxidants Cheng Qian Eric Andrew Decker Hang Xiao David Julian McClements Volume 135 Issue 3 1 December 2012 Pages 1036ndash1043

Functional food components ndash Carotenoids

β-carotene enriched oil-in-water nanoemulsions stabilized by different emulsifiers with either no antioxidants (control) or antioxidants (80 μM EDTA + 10000 ppm vitamin E acetate)

Functional food components ndash Polyphenols

Pomegranate Phenolics from the Peels Arils and Flowers Are Antiatherogenic Studies in Vivo in Atherosclerotic Apolipoprotein E-Deficient (E0) Mice and in Vitro in Cultured Macrophages and Lipoproteins J Agric Food Chem 2008 56 (3) pp 1148ndash1157

Pomegranate phenolics and mainly oligomers punicalagin punicalin and gallic and ellagic acids are major contributors to the beneficial effects of pomegranate juice

Functional food components ndash Antioxidant activity

J Med Food 2012 Nov15(11)968-73 doi 101089jmf20122282 Epub 2012 Oct 12 Prickly pear cactus (Opuntia ficus indica var saboten) protects against stress-induced acute gastric lesions in rats (maltodextrin y betanin)

httpcancerpreventionresearchaacrjournalsorgcontentearly200906191940-6207CAPR-08-0167abstract

Tea Polyphenols Decrease Serum Levels of Prostate-Specific Antigen Hepatocyte Growth Factor and Vascular Endothelial Growth Factor in Prostate Cancer Patients and Inhibit Production of Hepatocyte Growth Factor and Vascular Endothelial Growth Factor In vitro 2008 Jerry McLarty Rebecca LH Bigelow Mylinh Smith Don Elmajian Murali Ankem James A Cardelli

Functional food components ndash Polyphenols

ldquoNano-sized self assembled structured liquids = nanodrops Liquid carriers that pass through the digestive system effectively without sinking or breaking up to the absorption site These nanodrops carry the phytosterols to the large micelles that the body produces from the bile acid where they compete with cholesterol for entry into the micelle The phytosterols enter the micelle thereby inhibiting transportation of cholesterol from the digestive system into the bloodstreamrdquo Shemen Industries

Functional food components ndash Phytosterols

Goacutemez-Guilleacuten M C B Gimeacutenez et al (2011) Functional and bioactive properties of collagen and gelatin from alternative sources A review Food Hydrocolloids 25(8) 1813-1827

Functional food components ndash Bioactive peptides

httpwwwnuritascomscreening-mining-food-for-bioactive-peptides

Health and nutrition benefits associated with Fibregum its fermentation in the large bowel increases levels of beneficial bacteria which stimulates the production of short-chain fatty acids (SCFAs) that have such properties as lowering serum cholesterol it is a strong prebiotic helping to balance the intestinal microbial ecosystem in the distal colon

Functional food components ndash Prebiotic fiber

httpwwwnexiracomFibregumE284A2-healthy-prebiotic-fiber_6html

Senegalia senegal (acacia)

Functional food components ndash Essential minerals (Fe Zn Ca Se)

httpwwwfdagovFoodGuidanceRegulationGuidanceDocumentsRegulatoryInformationLabelingNutritionucm152626htm

Pseudocereals are considered an important energy source due to their starch content they also provide good quality protein dietary fibre and lipids rich in unsaturated fats They contain adequate levels of minerals and vitamins and significant amounts of other bioactive components such as saponins phytosterols squalene fagopyritols and polyphenols

Functional food components ndash micronutrients

httpquinuapewp-contentuploads201302antiox-Gallagherpdf

Seven-step process would ensure that functional foods are safe and effective with health claims that are accurate and regulatory oversight that is science based and efficient

Functional foods

FERGUS CLYDESDALE 2004 Functional Foods Opportunities amp Challenges Food Technology December 2004 Volume 58 No12

httpwwwgooglecompatentsUS20100196569

httpwwwgooglecompatentsWO2006048158A1cl=en

httpswwwgooglecompatentsUS6428824pg=PA2ampdq=Lepidium+peruvianumamphl=enampsa=Xampei=KxK2UanpKvOu4AOehICgDwampved=0CDoQ6AEwATgK

httpswwwgooglecompatentsUS7005148pg=PA3ampdq=vaccinium+corymbosumamphl=enampsa=Xampei=-xK2UZ7vF_a64AO0soG4Cgampsqi=2amppjf=1ampved=0CGwQ6AEwCA

httpswwwgooglecompatentsWO2001045648A2cl=enampdq=vaccinium+corymbosumamphl=enampsa=Xampei=9BO2Uc_5A9Sz4AOrsIEIampved=0CDQQ6AEwAA

Potential for future researchhellip

Top health issues consumers are concerned about preventing From NMI(2005)

A ELIZABETH SLOAN 2006 Top 10 Functional Food Trends Food Technology Volume 60 No 4

Enzymes ndash for food processing

Lactase

ldquoLactase produced commercially can be extracted both from yeasts such as Kluyveromyces fragilis and Kluyveromyces lactis and from fungi such as Aspergillus niger and Aspergillus oryzae Its primary commercial use is to break down lactose in milk to make it suitable for people with lactose intolerancerdquo wwwwikipediaorg

Enzymes ndash for food processing Protease

Calf rennet

Vegetable rennet Cynara cardunculus

Fermentation-produced chymosin Aspergillus niger var awamori GM

Enzymes ndash for food processing Protease

Papain

Meat is sprinkled with the powder and the enzymes help to break down the meat fibers

httpwwwenzymedevelopmentcomapplicationstenderizer

Use of Mucor miehei Lipase to Improve Functional Properties of Yolk-Contaminated Egg Whites Laura N Macherey Frank D Conforti William Eigel III Sean F OrsquoKeefe Journal of Food Science Volume 76 Issue 4 pages C651ndashC655 May 2011

Enzymes ndash for food processing

Lipase

Microorganisms ndash ingredients production

ldquoCorynebacterium glutamicum was discovered in the 1950s in Japan as natural producer of glutamic acid It is now produced by direct fermentation used for industrial production of amino acids which are used as flavour enhancers in foodrdquo

Glutamic acid amp Lysine

httpbacmapwishartlabcomorganisms485

Microorganisms ndash ingredients production

Citric acid

ldquoCultures of A niger are fed on a sucrose or glucose-containing medium to produce citric acid The source of sugar is corn steep liquor molasses hydrolyzed corn starch or other inexpensive sugary solutionsrdquo

httpgenomejgi-psforgAspni5Aspni5homehtml

Microorganisms ndash ingredients production

Bacillus subtilis has been genetically modified to both increase the bacterias production of riboflavin and to introduce an antibiotic (ampicillin) resistance marker wwwwikipediaorg

Riboflavin (Vitamin B2)

httpwwwocrawdogcomcat-chickenhtm

Colored scanning electron micrographs of representative cheese starter (A-C) and nonstarter (D-F) lactic acid bacteria (LAB) Lactobacillus helveticus (A) Lb delbrueckii subsp bulgaricus (B) Lactococcus lactis (C) Lb casei (D) Pediococcus pentosaceus (E) and Lb brevis (F)

Cheese

Microorganisms ndash fermented products

Microorganisms ndash fermented products

McSweeney P(2004) Biochemistry of cheese ripening Vol 57 (2-3) Int J Dairy Technol

Cheese_ Emmental

Microorganisms ndash fermented products

ldquoIn the late stage of cheese production P freudenreichii consumes the lactic acid excreted by the other bacteria and releases carbon dioxide gas which slowly forms the bubbles that make holesrdquo wwwwikipediaorg

Streptococcus thermophilus Lactobacillus debrueckii helveticus and Propionibacterium freudenreichii

Cheese_ Gouda

Microorganisms ndash fermented products

Lactococcus lactis ssp cremoris lactis Leuconostoc mesenteroides ssp cremoris

Leuconostoc mesenteroides ssp cremoris are starter cultures used for flavor and aroma development through the production of diacetyl from citrate

Roquefort

Microorganisms ndash fermented products

Camembert

ldquoPenicillium roqueforti and Penicillium caseicolum possess very potent proteolytic systems The molds secrete acid and neutral metalloproteinases and several aminopeptidases and carboxypeptidases The mycelia also contain intracellular proteinases and peptidases that are probably released when the mould dies and lysesrdquo

Microorganisms ndash fermented products

Fermented milks

Microorganisms ndash fermented products

Fermented milks

ldquoKefir grains are a combination of bacteria and yeasts in a matrix of proteins lipids and sugars and this symbiotic matrix forms grains that resemble cauliflower For this reason a complex and highly variable community of lactic acid bacteria and yeasts can be found in these grainsrdquo wwwwikipediaorg

Genus Lactobacillus Leuconostoc Pediococcus Streptococcus Bifidobacerium

Microorganisms ndash fermented products Fermented meats

Hutkins Robert W Microbiology and Technology of Fermented Foods

Pediococcus pentosaceus

httpbiowebusueduemlabcurrent20newshtml

Microorganisms ndash fermented products

Meat cultures

Lactobacillus sakei 10000-times magnified (Bild Joumlrg Groth Blessing Biotech GmbH)

Lactobacillus curvatus Lactobacillus plantarum Lactobacillus pentosus Streptococcus carnosus Micrococcus varians

httpwwwwzwtumdeindexphpid=185ampL=1amptx_ttnews5Btt_news5D=280

Microorganisms ndash fermented products

Meat cultures

httpwwwchr-hansencomproductsproduct-areasmeat-cultureshtml

Microorganisms ndash fermented products

Salami

ldquoPenicillium nalgiovense P chrysogenum and P camenberti used as starters The mold is desired as it imparts flavor helps the drying process prevents spoilage (mainly preventing growth of other mycotoxin-producing moulds during the curing process) and give a typical white color on the surfacerdquo

Microorganisms ndash fermented products

Wine amp Beer

Microorganisms ndash fermented products

Wine amp Beer

ldquoDuring fermentation the yeast converts the sugar in the wort to alcohol and carbon dioxide in addition to small amounts of glycerol and acetic acidrdquo

Yeast of the species Saccharomyces cerevisiae

httpenwikipediaorgwikiYeast

Microorganisms ndash other fermented products

httpwwwpsmicrographscoukrhizopus-mould--rhizopus-oligosporus-science-image80012871

Tempeh

Tempeh is manufactured from soaked boiled and dired soybeans that are inoculated with mold spores of species of Rhizopus (R stolonifer R oryzae R oigosporus or R arrhizus) The mash is packed or rolled in banana leaves and then incubated until there is good growth of mycelium but little sporulation Machve KK Fermentation Technology 2009

Functional food components

Critical Reviews in Food Science and Nutrition Structural Design Principles for Delivery of Bioactive Components in Nutraceuticals and Functional Foods 2011 McClements J Andrew E Yeonhwa D amp Weiss J

BioBest Omega 3 probiotic yogurt is a source of omega-3 PUFA that are considered an important part of a healthy diet It also contains over 1 billion active probiotic cultures Lactobacillus acidophilus NCFM Bifidobacterium lactis Bi-07 per serving that contribute to healthy digestive tract flora httpwwwastrocaproductsbiobest_omega_3_12x100g_multipackUbJJb_nVA8s

Functional food components ndash Omega 3

Inhibition of β-carotene degradation in oil-in-water nanoemulsions Influence of oil-soluble and water-soluble antioxidants Cheng Qian Eric Andrew Decker Hang Xiao David Julian McClements Volume 135 Issue 3 1 December 2012 Pages 1036ndash1043

Functional food components ndash Carotenoids

β-carotene enriched oil-in-water nanoemulsions stabilized by different emulsifiers with either no antioxidants (control) or antioxidants (80 μM EDTA + 10000 ppm vitamin E acetate)

Functional food components ndash Polyphenols

Pomegranate Phenolics from the Peels Arils and Flowers Are Antiatherogenic Studies in Vivo in Atherosclerotic Apolipoprotein E-Deficient (E0) Mice and in Vitro in Cultured Macrophages and Lipoproteins J Agric Food Chem 2008 56 (3) pp 1148ndash1157

Pomegranate phenolics and mainly oligomers punicalagin punicalin and gallic and ellagic acids are major contributors to the beneficial effects of pomegranate juice

Functional food components ndash Antioxidant activity

J Med Food 2012 Nov15(11)968-73 doi 101089jmf20122282 Epub 2012 Oct 12 Prickly pear cactus (Opuntia ficus indica var saboten) protects against stress-induced acute gastric lesions in rats (maltodextrin y betanin)

httpcancerpreventionresearchaacrjournalsorgcontentearly200906191940-6207CAPR-08-0167abstract

Tea Polyphenols Decrease Serum Levels of Prostate-Specific Antigen Hepatocyte Growth Factor and Vascular Endothelial Growth Factor in Prostate Cancer Patients and Inhibit Production of Hepatocyte Growth Factor and Vascular Endothelial Growth Factor In vitro 2008 Jerry McLarty Rebecca LH Bigelow Mylinh Smith Don Elmajian Murali Ankem James A Cardelli

Functional food components ndash Polyphenols

ldquoNano-sized self assembled structured liquids = nanodrops Liquid carriers that pass through the digestive system effectively without sinking or breaking up to the absorption site These nanodrops carry the phytosterols to the large micelles that the body produces from the bile acid where they compete with cholesterol for entry into the micelle The phytosterols enter the micelle thereby inhibiting transportation of cholesterol from the digestive system into the bloodstreamrdquo Shemen Industries

Functional food components ndash Phytosterols

Goacutemez-Guilleacuten M C B Gimeacutenez et al (2011) Functional and bioactive properties of collagen and gelatin from alternative sources A review Food Hydrocolloids 25(8) 1813-1827

Functional food components ndash Bioactive peptides

httpwwwnuritascomscreening-mining-food-for-bioactive-peptides

Health and nutrition benefits associated with Fibregum its fermentation in the large bowel increases levels of beneficial bacteria which stimulates the production of short-chain fatty acids (SCFAs) that have such properties as lowering serum cholesterol it is a strong prebiotic helping to balance the intestinal microbial ecosystem in the distal colon

Functional food components ndash Prebiotic fiber

httpwwwnexiracomFibregumE284A2-healthy-prebiotic-fiber_6html

Senegalia senegal (acacia)

Functional food components ndash Essential minerals (Fe Zn Ca Se)

httpwwwfdagovFoodGuidanceRegulationGuidanceDocumentsRegulatoryInformationLabelingNutritionucm152626htm

Pseudocereals are considered an important energy source due to their starch content they also provide good quality protein dietary fibre and lipids rich in unsaturated fats They contain adequate levels of minerals and vitamins and significant amounts of other bioactive components such as saponins phytosterols squalene fagopyritols and polyphenols

Functional food components ndash micronutrients

httpquinuapewp-contentuploads201302antiox-Gallagherpdf

Seven-step process would ensure that functional foods are safe and effective with health claims that are accurate and regulatory oversight that is science based and efficient

Functional foods

FERGUS CLYDESDALE 2004 Functional Foods Opportunities amp Challenges Food Technology December 2004 Volume 58 No12

httpwwwgooglecompatentsUS20100196569

httpwwwgooglecompatentsWO2006048158A1cl=en

httpswwwgooglecompatentsUS6428824pg=PA2ampdq=Lepidium+peruvianumamphl=enampsa=Xampei=KxK2UanpKvOu4AOehICgDwampved=0CDoQ6AEwATgK

httpswwwgooglecompatentsUS7005148pg=PA3ampdq=vaccinium+corymbosumamphl=enampsa=Xampei=-xK2UZ7vF_a64AO0soG4Cgampsqi=2amppjf=1ampved=0CGwQ6AEwCA

httpswwwgooglecompatentsWO2001045648A2cl=enampdq=vaccinium+corymbosumamphl=enampsa=Xampei=9BO2Uc_5A9Sz4AOrsIEIampved=0CDQQ6AEwAA

Potential for future researchhellip

Top health issues consumers are concerned about preventing From NMI(2005)

A ELIZABETH SLOAN 2006 Top 10 Functional Food Trends Food Technology Volume 60 No 4

Enzymes ndash for food processing Protease

Calf rennet

Vegetable rennet Cynara cardunculus

Fermentation-produced chymosin Aspergillus niger var awamori GM

Enzymes ndash for food processing Protease

Papain

Meat is sprinkled with the powder and the enzymes help to break down the meat fibers

httpwwwenzymedevelopmentcomapplicationstenderizer

Use of Mucor miehei Lipase to Improve Functional Properties of Yolk-Contaminated Egg Whites Laura N Macherey Frank D Conforti William Eigel III Sean F OrsquoKeefe Journal of Food Science Volume 76 Issue 4 pages C651ndashC655 May 2011

Enzymes ndash for food processing

Lipase

Microorganisms ndash ingredients production

ldquoCorynebacterium glutamicum was discovered in the 1950s in Japan as natural producer of glutamic acid It is now produced by direct fermentation used for industrial production of amino acids which are used as flavour enhancers in foodrdquo

Glutamic acid amp Lysine

httpbacmapwishartlabcomorganisms485

Microorganisms ndash ingredients production

Citric acid

ldquoCultures of A niger are fed on a sucrose or glucose-containing medium to produce citric acid The source of sugar is corn steep liquor molasses hydrolyzed corn starch or other inexpensive sugary solutionsrdquo

httpgenomejgi-psforgAspni5Aspni5homehtml

Microorganisms ndash ingredients production

Bacillus subtilis has been genetically modified to both increase the bacterias production of riboflavin and to introduce an antibiotic (ampicillin) resistance marker wwwwikipediaorg

Riboflavin (Vitamin B2)

httpwwwocrawdogcomcat-chickenhtm

Colored scanning electron micrographs of representative cheese starter (A-C) and nonstarter (D-F) lactic acid bacteria (LAB) Lactobacillus helveticus (A) Lb delbrueckii subsp bulgaricus (B) Lactococcus lactis (C) Lb casei (D) Pediococcus pentosaceus (E) and Lb brevis (F)

Cheese

Microorganisms ndash fermented products

Microorganisms ndash fermented products

McSweeney P(2004) Biochemistry of cheese ripening Vol 57 (2-3) Int J Dairy Technol

Cheese_ Emmental

Microorganisms ndash fermented products

ldquoIn the late stage of cheese production P freudenreichii consumes the lactic acid excreted by the other bacteria and releases carbon dioxide gas which slowly forms the bubbles that make holesrdquo wwwwikipediaorg

Streptococcus thermophilus Lactobacillus debrueckii helveticus and Propionibacterium freudenreichii

Cheese_ Gouda

Microorganisms ndash fermented products

Lactococcus lactis ssp cremoris lactis Leuconostoc mesenteroides ssp cremoris

Leuconostoc mesenteroides ssp cremoris are starter cultures used for flavor and aroma development through the production of diacetyl from citrate

Roquefort

Microorganisms ndash fermented products

Camembert

ldquoPenicillium roqueforti and Penicillium caseicolum possess very potent proteolytic systems The molds secrete acid and neutral metalloproteinases and several aminopeptidases and carboxypeptidases The mycelia also contain intracellular proteinases and peptidases that are probably released when the mould dies and lysesrdquo

Microorganisms ndash fermented products

Fermented milks

Microorganisms ndash fermented products

Fermented milks

ldquoKefir grains are a combination of bacteria and yeasts in a matrix of proteins lipids and sugars and this symbiotic matrix forms grains that resemble cauliflower For this reason a complex and highly variable community of lactic acid bacteria and yeasts can be found in these grainsrdquo wwwwikipediaorg

Genus Lactobacillus Leuconostoc Pediococcus Streptococcus Bifidobacerium

Microorganisms ndash fermented products Fermented meats

Hutkins Robert W Microbiology and Technology of Fermented Foods

Pediococcus pentosaceus

httpbiowebusueduemlabcurrent20newshtml

Microorganisms ndash fermented products

Meat cultures

Lactobacillus sakei 10000-times magnified (Bild Joumlrg Groth Blessing Biotech GmbH)

Lactobacillus curvatus Lactobacillus plantarum Lactobacillus pentosus Streptococcus carnosus Micrococcus varians

httpwwwwzwtumdeindexphpid=185ampL=1amptx_ttnews5Btt_news5D=280

Microorganisms ndash fermented products

Meat cultures

httpwwwchr-hansencomproductsproduct-areasmeat-cultureshtml

Microorganisms ndash fermented products

Salami

ldquoPenicillium nalgiovense P chrysogenum and P camenberti used as starters The mold is desired as it imparts flavor helps the drying process prevents spoilage (mainly preventing growth of other mycotoxin-producing moulds during the curing process) and give a typical white color on the surfacerdquo

Microorganisms ndash fermented products

Wine amp Beer

Microorganisms ndash fermented products

Wine amp Beer

ldquoDuring fermentation the yeast converts the sugar in the wort to alcohol and carbon dioxide in addition to small amounts of glycerol and acetic acidrdquo

Yeast of the species Saccharomyces cerevisiae

httpenwikipediaorgwikiYeast

Microorganisms ndash other fermented products

httpwwwpsmicrographscoukrhizopus-mould--rhizopus-oligosporus-science-image80012871

Tempeh

Tempeh is manufactured from soaked boiled and dired soybeans that are inoculated with mold spores of species of Rhizopus (R stolonifer R oryzae R oigosporus or R arrhizus) The mash is packed or rolled in banana leaves and then incubated until there is good growth of mycelium but little sporulation Machve KK Fermentation Technology 2009

Functional food components

Critical Reviews in Food Science and Nutrition Structural Design Principles for Delivery of Bioactive Components in Nutraceuticals and Functional Foods 2011 McClements J Andrew E Yeonhwa D amp Weiss J

BioBest Omega 3 probiotic yogurt is a source of omega-3 PUFA that are considered an important part of a healthy diet It also contains over 1 billion active probiotic cultures Lactobacillus acidophilus NCFM Bifidobacterium lactis Bi-07 per serving that contribute to healthy digestive tract flora httpwwwastrocaproductsbiobest_omega_3_12x100g_multipackUbJJb_nVA8s

Functional food components ndash Omega 3

Inhibition of β-carotene degradation in oil-in-water nanoemulsions Influence of oil-soluble and water-soluble antioxidants Cheng Qian Eric Andrew Decker Hang Xiao David Julian McClements Volume 135 Issue 3 1 December 2012 Pages 1036ndash1043

Functional food components ndash Carotenoids

β-carotene enriched oil-in-water nanoemulsions stabilized by different emulsifiers with either no antioxidants (control) or antioxidants (80 μM EDTA + 10000 ppm vitamin E acetate)

Functional food components ndash Polyphenols

Pomegranate Phenolics from the Peels Arils and Flowers Are Antiatherogenic Studies in Vivo in Atherosclerotic Apolipoprotein E-Deficient (E0) Mice and in Vitro in Cultured Macrophages and Lipoproteins J Agric Food Chem 2008 56 (3) pp 1148ndash1157

Pomegranate phenolics and mainly oligomers punicalagin punicalin and gallic and ellagic acids are major contributors to the beneficial effects of pomegranate juice

Functional food components ndash Antioxidant activity

J Med Food 2012 Nov15(11)968-73 doi 101089jmf20122282 Epub 2012 Oct 12 Prickly pear cactus (Opuntia ficus indica var saboten) protects against stress-induced acute gastric lesions in rats (maltodextrin y betanin)

httpcancerpreventionresearchaacrjournalsorgcontentearly200906191940-6207CAPR-08-0167abstract

Tea Polyphenols Decrease Serum Levels of Prostate-Specific Antigen Hepatocyte Growth Factor and Vascular Endothelial Growth Factor in Prostate Cancer Patients and Inhibit Production of Hepatocyte Growth Factor and Vascular Endothelial Growth Factor In vitro 2008 Jerry McLarty Rebecca LH Bigelow Mylinh Smith Don Elmajian Murali Ankem James A Cardelli

Functional food components ndash Polyphenols

ldquoNano-sized self assembled structured liquids = nanodrops Liquid carriers that pass through the digestive system effectively without sinking or breaking up to the absorption site These nanodrops carry the phytosterols to the large micelles that the body produces from the bile acid where they compete with cholesterol for entry into the micelle The phytosterols enter the micelle thereby inhibiting transportation of cholesterol from the digestive system into the bloodstreamrdquo Shemen Industries

Functional food components ndash Phytosterols

Goacutemez-Guilleacuten M C B Gimeacutenez et al (2011) Functional and bioactive properties of collagen and gelatin from alternative sources A review Food Hydrocolloids 25(8) 1813-1827

Functional food components ndash Bioactive peptides

httpwwwnuritascomscreening-mining-food-for-bioactive-peptides

Health and nutrition benefits associated with Fibregum its fermentation in the large bowel increases levels of beneficial bacteria which stimulates the production of short-chain fatty acids (SCFAs) that have such properties as lowering serum cholesterol it is a strong prebiotic helping to balance the intestinal microbial ecosystem in the distal colon

Functional food components ndash Prebiotic fiber

httpwwwnexiracomFibregumE284A2-healthy-prebiotic-fiber_6html

Senegalia senegal (acacia)

Functional food components ndash Essential minerals (Fe Zn Ca Se)

httpwwwfdagovFoodGuidanceRegulationGuidanceDocumentsRegulatoryInformationLabelingNutritionucm152626htm

Pseudocereals are considered an important energy source due to their starch content they also provide good quality protein dietary fibre and lipids rich in unsaturated fats They contain adequate levels of minerals and vitamins and significant amounts of other bioactive components such as saponins phytosterols squalene fagopyritols and polyphenols

Functional food components ndash micronutrients

httpquinuapewp-contentuploads201302antiox-Gallagherpdf

Seven-step process would ensure that functional foods are safe and effective with health claims that are accurate and regulatory oversight that is science based and efficient

Functional foods

FERGUS CLYDESDALE 2004 Functional Foods Opportunities amp Challenges Food Technology December 2004 Volume 58 No12

httpwwwgooglecompatentsUS20100196569

httpwwwgooglecompatentsWO2006048158A1cl=en

httpswwwgooglecompatentsUS6428824pg=PA2ampdq=Lepidium+peruvianumamphl=enampsa=Xampei=KxK2UanpKvOu4AOehICgDwampved=0CDoQ6AEwATgK

httpswwwgooglecompatentsUS7005148pg=PA3ampdq=vaccinium+corymbosumamphl=enampsa=Xampei=-xK2UZ7vF_a64AO0soG4Cgampsqi=2amppjf=1ampved=0CGwQ6AEwCA

httpswwwgooglecompatentsWO2001045648A2cl=enampdq=vaccinium+corymbosumamphl=enampsa=Xampei=9BO2Uc_5A9Sz4AOrsIEIampved=0CDQQ6AEwAA

Potential for future researchhellip

Top health issues consumers are concerned about preventing From NMI(2005)

A ELIZABETH SLOAN 2006 Top 10 Functional Food Trends Food Technology Volume 60 No 4

Enzymes ndash for food processing Protease

Papain

Meat is sprinkled with the powder and the enzymes help to break down the meat fibers

httpwwwenzymedevelopmentcomapplicationstenderizer

Use of Mucor miehei Lipase to Improve Functional Properties of Yolk-Contaminated Egg Whites Laura N Macherey Frank D Conforti William Eigel III Sean F OrsquoKeefe Journal of Food Science Volume 76 Issue 4 pages C651ndashC655 May 2011

Enzymes ndash for food processing

Lipase

Microorganisms ndash ingredients production

ldquoCorynebacterium glutamicum was discovered in the 1950s in Japan as natural producer of glutamic acid It is now produced by direct fermentation used for industrial production of amino acids which are used as flavour enhancers in foodrdquo

Glutamic acid amp Lysine

httpbacmapwishartlabcomorganisms485

Microorganisms ndash ingredients production

Citric acid

ldquoCultures of A niger are fed on a sucrose or glucose-containing medium to produce citric acid The source of sugar is corn steep liquor molasses hydrolyzed corn starch or other inexpensive sugary solutionsrdquo

httpgenomejgi-psforgAspni5Aspni5homehtml

Microorganisms ndash ingredients production

Bacillus subtilis has been genetically modified to both increase the bacterias production of riboflavin and to introduce an antibiotic (ampicillin) resistance marker wwwwikipediaorg

Riboflavin (Vitamin B2)

httpwwwocrawdogcomcat-chickenhtm

Colored scanning electron micrographs of representative cheese starter (A-C) and nonstarter (D-F) lactic acid bacteria (LAB) Lactobacillus helveticus (A) Lb delbrueckii subsp bulgaricus (B) Lactococcus lactis (C) Lb casei (D) Pediococcus pentosaceus (E) and Lb brevis (F)

Cheese

Microorganisms ndash fermented products

Microorganisms ndash fermented products

McSweeney P(2004) Biochemistry of cheese ripening Vol 57 (2-3) Int J Dairy Technol

Cheese_ Emmental

Microorganisms ndash fermented products

ldquoIn the late stage of cheese production P freudenreichii consumes the lactic acid excreted by the other bacteria and releases carbon dioxide gas which slowly forms the bubbles that make holesrdquo wwwwikipediaorg

Streptococcus thermophilus Lactobacillus debrueckii helveticus and Propionibacterium freudenreichii

Cheese_ Gouda

Microorganisms ndash fermented products

Lactococcus lactis ssp cremoris lactis Leuconostoc mesenteroides ssp cremoris

Leuconostoc mesenteroides ssp cremoris are starter cultures used for flavor and aroma development through the production of diacetyl from citrate

Roquefort

Microorganisms ndash fermented products

Camembert

ldquoPenicillium roqueforti and Penicillium caseicolum possess very potent proteolytic systems The molds secrete acid and neutral metalloproteinases and several aminopeptidases and carboxypeptidases The mycelia also contain intracellular proteinases and peptidases that are probably released when the mould dies and lysesrdquo

Microorganisms ndash fermented products

Fermented milks

Microorganisms ndash fermented products

Fermented milks

ldquoKefir grains are a combination of bacteria and yeasts in a matrix of proteins lipids and sugars and this symbiotic matrix forms grains that resemble cauliflower For this reason a complex and highly variable community of lactic acid bacteria and yeasts can be found in these grainsrdquo wwwwikipediaorg

Genus Lactobacillus Leuconostoc Pediococcus Streptococcus Bifidobacerium

Microorganisms ndash fermented products Fermented meats

Hutkins Robert W Microbiology and Technology of Fermented Foods

Pediococcus pentosaceus

httpbiowebusueduemlabcurrent20newshtml

Microorganisms ndash fermented products

Meat cultures

Lactobacillus sakei 10000-times magnified (Bild Joumlrg Groth Blessing Biotech GmbH)

Lactobacillus curvatus Lactobacillus plantarum Lactobacillus pentosus Streptococcus carnosus Micrococcus varians

httpwwwwzwtumdeindexphpid=185ampL=1amptx_ttnews5Btt_news5D=280

Microorganisms ndash fermented products

Meat cultures

httpwwwchr-hansencomproductsproduct-areasmeat-cultureshtml

Microorganisms ndash fermented products

Salami

ldquoPenicillium nalgiovense P chrysogenum and P camenberti used as starters The mold is desired as it imparts flavor helps the drying process prevents spoilage (mainly preventing growth of other mycotoxin-producing moulds during the curing process) and give a typical white color on the surfacerdquo

Microorganisms ndash fermented products

Wine amp Beer

Microorganisms ndash fermented products

Wine amp Beer

ldquoDuring fermentation the yeast converts the sugar in the wort to alcohol and carbon dioxide in addition to small amounts of glycerol and acetic acidrdquo

Yeast of the species Saccharomyces cerevisiae

httpenwikipediaorgwikiYeast

Microorganisms ndash other fermented products

httpwwwpsmicrographscoukrhizopus-mould--rhizopus-oligosporus-science-image80012871

Tempeh

Tempeh is manufactured from soaked boiled and dired soybeans that are inoculated with mold spores of species of Rhizopus (R stolonifer R oryzae R oigosporus or R arrhizus) The mash is packed or rolled in banana leaves and then incubated until there is good growth of mycelium but little sporulation Machve KK Fermentation Technology 2009

Functional food components

Critical Reviews in Food Science and Nutrition Structural Design Principles for Delivery of Bioactive Components in Nutraceuticals and Functional Foods 2011 McClements J Andrew E Yeonhwa D amp Weiss J

BioBest Omega 3 probiotic yogurt is a source of omega-3 PUFA that are considered an important part of a healthy diet It also contains over 1 billion active probiotic cultures Lactobacillus acidophilus NCFM Bifidobacterium lactis Bi-07 per serving that contribute to healthy digestive tract flora httpwwwastrocaproductsbiobest_omega_3_12x100g_multipackUbJJb_nVA8s

Functional food components ndash Omega 3

Inhibition of β-carotene degradation in oil-in-water nanoemulsions Influence of oil-soluble and water-soluble antioxidants Cheng Qian Eric Andrew Decker Hang Xiao David Julian McClements Volume 135 Issue 3 1 December 2012 Pages 1036ndash1043

Functional food components ndash Carotenoids

β-carotene enriched oil-in-water nanoemulsions stabilized by different emulsifiers with either no antioxidants (control) or antioxidants (80 μM EDTA + 10000 ppm vitamin E acetate)

Functional food components ndash Polyphenols

Pomegranate Phenolics from the Peels Arils and Flowers Are Antiatherogenic Studies in Vivo in Atherosclerotic Apolipoprotein E-Deficient (E0) Mice and in Vitro in Cultured Macrophages and Lipoproteins J Agric Food Chem 2008 56 (3) pp 1148ndash1157

Pomegranate phenolics and mainly oligomers punicalagin punicalin and gallic and ellagic acids are major contributors to the beneficial effects of pomegranate juice

Functional food components ndash Antioxidant activity

J Med Food 2012 Nov15(11)968-73 doi 101089jmf20122282 Epub 2012 Oct 12 Prickly pear cactus (Opuntia ficus indica var saboten) protects against stress-induced acute gastric lesions in rats (maltodextrin y betanin)

httpcancerpreventionresearchaacrjournalsorgcontentearly200906191940-6207CAPR-08-0167abstract

Tea Polyphenols Decrease Serum Levels of Prostate-Specific Antigen Hepatocyte Growth Factor and Vascular Endothelial Growth Factor in Prostate Cancer Patients and Inhibit Production of Hepatocyte Growth Factor and Vascular Endothelial Growth Factor In vitro 2008 Jerry McLarty Rebecca LH Bigelow Mylinh Smith Don Elmajian Murali Ankem James A Cardelli

Functional food components ndash Polyphenols

ldquoNano-sized self assembled structured liquids = nanodrops Liquid carriers that pass through the digestive system effectively without sinking or breaking up to the absorption site These nanodrops carry the phytosterols to the large micelles that the body produces from the bile acid where they compete with cholesterol for entry into the micelle The phytosterols enter the micelle thereby inhibiting transportation of cholesterol from the digestive system into the bloodstreamrdquo Shemen Industries

Functional food components ndash Phytosterols

Goacutemez-Guilleacuten M C B Gimeacutenez et al (2011) Functional and bioactive properties of collagen and gelatin from alternative sources A review Food Hydrocolloids 25(8) 1813-1827

Functional food components ndash Bioactive peptides

httpwwwnuritascomscreening-mining-food-for-bioactive-peptides

Health and nutrition benefits associated with Fibregum its fermentation in the large bowel increases levels of beneficial bacteria which stimulates the production of short-chain fatty acids (SCFAs) that have such properties as lowering serum cholesterol it is a strong prebiotic helping to balance the intestinal microbial ecosystem in the distal colon

Functional food components ndash Prebiotic fiber

httpwwwnexiracomFibregumE284A2-healthy-prebiotic-fiber_6html

Senegalia senegal (acacia)

Functional food components ndash Essential minerals (Fe Zn Ca Se)

httpwwwfdagovFoodGuidanceRegulationGuidanceDocumentsRegulatoryInformationLabelingNutritionucm152626htm

Pseudocereals are considered an important energy source due to their starch content they also provide good quality protein dietary fibre and lipids rich in unsaturated fats They contain adequate levels of minerals and vitamins and significant amounts of other bioactive components such as saponins phytosterols squalene fagopyritols and polyphenols

Functional food components ndash micronutrients

httpquinuapewp-contentuploads201302antiox-Gallagherpdf

Seven-step process would ensure that functional foods are safe and effective with health claims that are accurate and regulatory oversight that is science based and efficient

Functional foods

FERGUS CLYDESDALE 2004 Functional Foods Opportunities amp Challenges Food Technology December 2004 Volume 58 No12

httpwwwgooglecompatentsUS20100196569

httpwwwgooglecompatentsWO2006048158A1cl=en

httpswwwgooglecompatentsUS6428824pg=PA2ampdq=Lepidium+peruvianumamphl=enampsa=Xampei=KxK2UanpKvOu4AOehICgDwampved=0CDoQ6AEwATgK

httpswwwgooglecompatentsUS7005148pg=PA3ampdq=vaccinium+corymbosumamphl=enampsa=Xampei=-xK2UZ7vF_a64AO0soG4Cgampsqi=2amppjf=1ampved=0CGwQ6AEwCA

httpswwwgooglecompatentsWO2001045648A2cl=enampdq=vaccinium+corymbosumamphl=enampsa=Xampei=9BO2Uc_5A9Sz4AOrsIEIampved=0CDQQ6AEwAA

Potential for future researchhellip

Top health issues consumers are concerned about preventing From NMI(2005)

A ELIZABETH SLOAN 2006 Top 10 Functional Food Trends Food Technology Volume 60 No 4

Use of Mucor miehei Lipase to Improve Functional Properties of Yolk-Contaminated Egg Whites Laura N Macherey Frank D Conforti William Eigel III Sean F OrsquoKeefe Journal of Food Science Volume 76 Issue 4 pages C651ndashC655 May 2011

Enzymes ndash for food processing

Lipase

Microorganisms ndash ingredients production

ldquoCorynebacterium glutamicum was discovered in the 1950s in Japan as natural producer of glutamic acid It is now produced by direct fermentation used for industrial production of amino acids which are used as flavour enhancers in foodrdquo

Glutamic acid amp Lysine

httpbacmapwishartlabcomorganisms485

Microorganisms ndash ingredients production

Citric acid

ldquoCultures of A niger are fed on a sucrose or glucose-containing medium to produce citric acid The source of sugar is corn steep liquor molasses hydrolyzed corn starch or other inexpensive sugary solutionsrdquo

httpgenomejgi-psforgAspni5Aspni5homehtml

Microorganisms ndash ingredients production

Bacillus subtilis has been genetically modified to both increase the bacterias production of riboflavin and to introduce an antibiotic (ampicillin) resistance marker wwwwikipediaorg

Riboflavin (Vitamin B2)

httpwwwocrawdogcomcat-chickenhtm

Colored scanning electron micrographs of representative cheese starter (A-C) and nonstarter (D-F) lactic acid bacteria (LAB) Lactobacillus helveticus (A) Lb delbrueckii subsp bulgaricus (B) Lactococcus lactis (C) Lb casei (D) Pediococcus pentosaceus (E) and Lb brevis (F)

Cheese

Microorganisms ndash fermented products

Microorganisms ndash fermented products

McSweeney P(2004) Biochemistry of cheese ripening Vol 57 (2-3) Int J Dairy Technol

Cheese_ Emmental

Microorganisms ndash fermented products

ldquoIn the late stage of cheese production P freudenreichii consumes the lactic acid excreted by the other bacteria and releases carbon dioxide gas which slowly forms the bubbles that make holesrdquo wwwwikipediaorg

Streptococcus thermophilus Lactobacillus debrueckii helveticus and Propionibacterium freudenreichii

Cheese_ Gouda

Microorganisms ndash fermented products

Lactococcus lactis ssp cremoris lactis Leuconostoc mesenteroides ssp cremoris

Leuconostoc mesenteroides ssp cremoris are starter cultures used for flavor and aroma development through the production of diacetyl from citrate

Roquefort

Microorganisms ndash fermented products

Camembert

ldquoPenicillium roqueforti and Penicillium caseicolum possess very potent proteolytic systems The molds secrete acid and neutral metalloproteinases and several aminopeptidases and carboxypeptidases The mycelia also contain intracellular proteinases and peptidases that are probably released when the mould dies and lysesrdquo

Microorganisms ndash fermented products

Fermented milks

Microorganisms ndash fermented products

Fermented milks

ldquoKefir grains are a combination of bacteria and yeasts in a matrix of proteins lipids and sugars and this symbiotic matrix forms grains that resemble cauliflower For this reason a complex and highly variable community of lactic acid bacteria and yeasts can be found in these grainsrdquo wwwwikipediaorg

Genus Lactobacillus Leuconostoc Pediococcus Streptococcus Bifidobacerium

Microorganisms ndash fermented products Fermented meats

Hutkins Robert W Microbiology and Technology of Fermented Foods

Pediococcus pentosaceus

httpbiowebusueduemlabcurrent20newshtml

Microorganisms ndash fermented products

Meat cultures

Lactobacillus sakei 10000-times magnified (Bild Joumlrg Groth Blessing Biotech GmbH)

Lactobacillus curvatus Lactobacillus plantarum Lactobacillus pentosus Streptococcus carnosus Micrococcus varians

httpwwwwzwtumdeindexphpid=185ampL=1amptx_ttnews5Btt_news5D=280

Microorganisms ndash fermented products

Meat cultures

httpwwwchr-hansencomproductsproduct-areasmeat-cultureshtml

Microorganisms ndash fermented products

Salami

ldquoPenicillium nalgiovense P chrysogenum and P camenberti used as starters The mold is desired as it imparts flavor helps the drying process prevents spoilage (mainly preventing growth of other mycotoxin-producing moulds during the curing process) and give a typical white color on the surfacerdquo

Microorganisms ndash fermented products

Wine amp Beer

Microorganisms ndash fermented products

Wine amp Beer

ldquoDuring fermentation the yeast converts the sugar in the wort to alcohol and carbon dioxide in addition to small amounts of glycerol and acetic acidrdquo

Yeast of the species Saccharomyces cerevisiae

httpenwikipediaorgwikiYeast

Microorganisms ndash other fermented products

httpwwwpsmicrographscoukrhizopus-mould--rhizopus-oligosporus-science-image80012871

Tempeh

Tempeh is manufactured from soaked boiled and dired soybeans that are inoculated with mold spores of species of Rhizopus (R stolonifer R oryzae R oigosporus or R arrhizus) The mash is packed or rolled in banana leaves and then incubated until there is good growth of mycelium but little sporulation Machve KK Fermentation Technology 2009

Functional food components

Critical Reviews in Food Science and Nutrition Structural Design Principles for Delivery of Bioactive Components in Nutraceuticals and Functional Foods 2011 McClements J Andrew E Yeonhwa D amp Weiss J

BioBest Omega 3 probiotic yogurt is a source of omega-3 PUFA that are considered an important part of a healthy diet It also contains over 1 billion active probiotic cultures Lactobacillus acidophilus NCFM Bifidobacterium lactis Bi-07 per serving that contribute to healthy digestive tract flora httpwwwastrocaproductsbiobest_omega_3_12x100g_multipackUbJJb_nVA8s

Functional food components ndash Omega 3

Inhibition of β-carotene degradation in oil-in-water nanoemulsions Influence of oil-soluble and water-soluble antioxidants Cheng Qian Eric Andrew Decker Hang Xiao David Julian McClements Volume 135 Issue 3 1 December 2012 Pages 1036ndash1043

Functional food components ndash Carotenoids

β-carotene enriched oil-in-water nanoemulsions stabilized by different emulsifiers with either no antioxidants (control) or antioxidants (80 μM EDTA + 10000 ppm vitamin E acetate)

Functional food components ndash Polyphenols

Pomegranate Phenolics from the Peels Arils and Flowers Are Antiatherogenic Studies in Vivo in Atherosclerotic Apolipoprotein E-Deficient (E0) Mice and in Vitro in Cultured Macrophages and Lipoproteins J Agric Food Chem 2008 56 (3) pp 1148ndash1157

Pomegranate phenolics and mainly oligomers punicalagin punicalin and gallic and ellagic acids are major contributors to the beneficial effects of pomegranate juice

Functional food components ndash Antioxidant activity

J Med Food 2012 Nov15(11)968-73 doi 101089jmf20122282 Epub 2012 Oct 12 Prickly pear cactus (Opuntia ficus indica var saboten) protects against stress-induced acute gastric lesions in rats (maltodextrin y betanin)

httpcancerpreventionresearchaacrjournalsorgcontentearly200906191940-6207CAPR-08-0167abstract

Tea Polyphenols Decrease Serum Levels of Prostate-Specific Antigen Hepatocyte Growth Factor and Vascular Endothelial Growth Factor in Prostate Cancer Patients and Inhibit Production of Hepatocyte Growth Factor and Vascular Endothelial Growth Factor In vitro 2008 Jerry McLarty Rebecca LH Bigelow Mylinh Smith Don Elmajian Murali Ankem James A Cardelli

Functional food components ndash Polyphenols

ldquoNano-sized self assembled structured liquids = nanodrops Liquid carriers that pass through the digestive system effectively without sinking or breaking up to the absorption site These nanodrops carry the phytosterols to the large micelles that the body produces from the bile acid where they compete with cholesterol for entry into the micelle The phytosterols enter the micelle thereby inhibiting transportation of cholesterol from the digestive system into the bloodstreamrdquo Shemen Industries

Functional food components ndash Phytosterols

Goacutemez-Guilleacuten M C B Gimeacutenez et al (2011) Functional and bioactive properties of collagen and gelatin from alternative sources A review Food Hydrocolloids 25(8) 1813-1827

Functional food components ndash Bioactive peptides

httpwwwnuritascomscreening-mining-food-for-bioactive-peptides

Health and nutrition benefits associated with Fibregum its fermentation in the large bowel increases levels of beneficial bacteria which stimulates the production of short-chain fatty acids (SCFAs) that have such properties as lowering serum cholesterol it is a strong prebiotic helping to balance the intestinal microbial ecosystem in the distal colon

Functional food components ndash Prebiotic fiber

httpwwwnexiracomFibregumE284A2-healthy-prebiotic-fiber_6html

Senegalia senegal (acacia)

Functional food components ndash Essential minerals (Fe Zn Ca Se)

httpwwwfdagovFoodGuidanceRegulationGuidanceDocumentsRegulatoryInformationLabelingNutritionucm152626htm

Pseudocereals are considered an important energy source due to their starch content they also provide good quality protein dietary fibre and lipids rich in unsaturated fats They contain adequate levels of minerals and vitamins and significant amounts of other bioactive components such as saponins phytosterols squalene fagopyritols and polyphenols

Functional food components ndash micronutrients

httpquinuapewp-contentuploads201302antiox-Gallagherpdf

Seven-step process would ensure that functional foods are safe and effective with health claims that are accurate and regulatory oversight that is science based and efficient

Functional foods

FERGUS CLYDESDALE 2004 Functional Foods Opportunities amp Challenges Food Technology December 2004 Volume 58 No12

httpwwwgooglecompatentsUS20100196569

httpwwwgooglecompatentsWO2006048158A1cl=en

httpswwwgooglecompatentsUS6428824pg=PA2ampdq=Lepidium+peruvianumamphl=enampsa=Xampei=KxK2UanpKvOu4AOehICgDwampved=0CDoQ6AEwATgK

httpswwwgooglecompatentsUS7005148pg=PA3ampdq=vaccinium+corymbosumamphl=enampsa=Xampei=-xK2UZ7vF_a64AO0soG4Cgampsqi=2amppjf=1ampved=0CGwQ6AEwCA

httpswwwgooglecompatentsWO2001045648A2cl=enampdq=vaccinium+corymbosumamphl=enampsa=Xampei=9BO2Uc_5A9Sz4AOrsIEIampved=0CDQQ6AEwAA

Potential for future researchhellip

Top health issues consumers are concerned about preventing From NMI(2005)

A ELIZABETH SLOAN 2006 Top 10 Functional Food Trends Food Technology Volume 60 No 4

Microorganisms ndash ingredients production

ldquoCorynebacterium glutamicum was discovered in the 1950s in Japan as natural producer of glutamic acid It is now produced by direct fermentation used for industrial production of amino acids which are used as flavour enhancers in foodrdquo

Glutamic acid amp Lysine

httpbacmapwishartlabcomorganisms485

Microorganisms ndash ingredients production

Citric acid

ldquoCultures of A niger are fed on a sucrose or glucose-containing medium to produce citric acid The source of sugar is corn steep liquor molasses hydrolyzed corn starch or other inexpensive sugary solutionsrdquo

httpgenomejgi-psforgAspni5Aspni5homehtml

Microorganisms ndash ingredients production

Bacillus subtilis has been genetically modified to both increase the bacterias production of riboflavin and to introduce an antibiotic (ampicillin) resistance marker wwwwikipediaorg

Riboflavin (Vitamin B2)

httpwwwocrawdogcomcat-chickenhtm

Colored scanning electron micrographs of representative cheese starter (A-C) and nonstarter (D-F) lactic acid bacteria (LAB) Lactobacillus helveticus (A) Lb delbrueckii subsp bulgaricus (B) Lactococcus lactis (C) Lb casei (D) Pediococcus pentosaceus (E) and Lb brevis (F)

Cheese

Microorganisms ndash fermented products

Microorganisms ndash fermented products

McSweeney P(2004) Biochemistry of cheese ripening Vol 57 (2-3) Int J Dairy Technol

Cheese_ Emmental

Microorganisms ndash fermented products

ldquoIn the late stage of cheese production P freudenreichii consumes the lactic acid excreted by the other bacteria and releases carbon dioxide gas which slowly forms the bubbles that make holesrdquo wwwwikipediaorg

Streptococcus thermophilus Lactobacillus debrueckii helveticus and Propionibacterium freudenreichii

Cheese_ Gouda

Microorganisms ndash fermented products

Lactococcus lactis ssp cremoris lactis Leuconostoc mesenteroides ssp cremoris

Leuconostoc mesenteroides ssp cremoris are starter cultures used for flavor and aroma development through the production of diacetyl from citrate

Roquefort

Microorganisms ndash fermented products

Camembert

ldquoPenicillium roqueforti and Penicillium caseicolum possess very potent proteolytic systems The molds secrete acid and neutral metalloproteinases and several aminopeptidases and carboxypeptidases The mycelia also contain intracellular proteinases and peptidases that are probably released when the mould dies and lysesrdquo

Microorganisms ndash fermented products

Fermented milks

Microorganisms ndash fermented products

Fermented milks

ldquoKefir grains are a combination of bacteria and yeasts in a matrix of proteins lipids and sugars and this symbiotic matrix forms grains that resemble cauliflower For this reason a complex and highly variable community of lactic acid bacteria and yeasts can be found in these grainsrdquo wwwwikipediaorg

Genus Lactobacillus Leuconostoc Pediococcus Streptococcus Bifidobacerium

Microorganisms ndash fermented products Fermented meats

Hutkins Robert W Microbiology and Technology of Fermented Foods

Pediococcus pentosaceus

httpbiowebusueduemlabcurrent20newshtml

Microorganisms ndash fermented products

Meat cultures

Lactobacillus sakei 10000-times magnified (Bild Joumlrg Groth Blessing Biotech GmbH)

Lactobacillus curvatus Lactobacillus plantarum Lactobacillus pentosus Streptococcus carnosus Micrococcus varians

httpwwwwzwtumdeindexphpid=185ampL=1amptx_ttnews5Btt_news5D=280

Microorganisms ndash fermented products

Meat cultures

httpwwwchr-hansencomproductsproduct-areasmeat-cultureshtml

Microorganisms ndash fermented products

Salami

ldquoPenicillium nalgiovense P chrysogenum and P camenberti used as starters The mold is desired as it imparts flavor helps the drying process prevents spoilage (mainly preventing growth of other mycotoxin-producing moulds during the curing process) and give a typical white color on the surfacerdquo

Microorganisms ndash fermented products

Wine amp Beer

Microorganisms ndash fermented products

Wine amp Beer

ldquoDuring fermentation the yeast converts the sugar in the wort to alcohol and carbon dioxide in addition to small amounts of glycerol and acetic acidrdquo

Yeast of the species Saccharomyces cerevisiae

httpenwikipediaorgwikiYeast

Microorganisms ndash other fermented products

httpwwwpsmicrographscoukrhizopus-mould--rhizopus-oligosporus-science-image80012871

Tempeh

Tempeh is manufactured from soaked boiled and dired soybeans that are inoculated with mold spores of species of Rhizopus (R stolonifer R oryzae R oigosporus or R arrhizus) The mash is packed or rolled in banana leaves and then incubated until there is good growth of mycelium but little sporulation Machve KK Fermentation Technology 2009

Functional food components

Critical Reviews in Food Science and Nutrition Structural Design Principles for Delivery of Bioactive Components in Nutraceuticals and Functional Foods 2011 McClements J Andrew E Yeonhwa D amp Weiss J

BioBest Omega 3 probiotic yogurt is a source of omega-3 PUFA that are considered an important part of a healthy diet It also contains over 1 billion active probiotic cultures Lactobacillus acidophilus NCFM Bifidobacterium lactis Bi-07 per serving that contribute to healthy digestive tract flora httpwwwastrocaproductsbiobest_omega_3_12x100g_multipackUbJJb_nVA8s

Functional food components ndash Omega 3

Inhibition of β-carotene degradation in oil-in-water nanoemulsions Influence of oil-soluble and water-soluble antioxidants Cheng Qian Eric Andrew Decker Hang Xiao David Julian McClements Volume 135 Issue 3 1 December 2012 Pages 1036ndash1043

Functional food components ndash Carotenoids

β-carotene enriched oil-in-water nanoemulsions stabilized by different emulsifiers with either no antioxidants (control) or antioxidants (80 μM EDTA + 10000 ppm vitamin E acetate)

Functional food components ndash Polyphenols

Pomegranate Phenolics from the Peels Arils and Flowers Are Antiatherogenic Studies in Vivo in Atherosclerotic Apolipoprotein E-Deficient (E0) Mice and in Vitro in Cultured Macrophages and Lipoproteins J Agric Food Chem 2008 56 (3) pp 1148ndash1157

Pomegranate phenolics and mainly oligomers punicalagin punicalin and gallic and ellagic acids are major contributors to the beneficial effects of pomegranate juice

Functional food components ndash Antioxidant activity

J Med Food 2012 Nov15(11)968-73 doi 101089jmf20122282 Epub 2012 Oct 12 Prickly pear cactus (Opuntia ficus indica var saboten) protects against stress-induced acute gastric lesions in rats (maltodextrin y betanin)

httpcancerpreventionresearchaacrjournalsorgcontentearly200906191940-6207CAPR-08-0167abstract

Tea Polyphenols Decrease Serum Levels of Prostate-Specific Antigen Hepatocyte Growth Factor and Vascular Endothelial Growth Factor in Prostate Cancer Patients and Inhibit Production of Hepatocyte Growth Factor and Vascular Endothelial Growth Factor In vitro 2008 Jerry McLarty Rebecca LH Bigelow Mylinh Smith Don Elmajian Murali Ankem James A Cardelli

Functional food components ndash Polyphenols

ldquoNano-sized self assembled structured liquids = nanodrops Liquid carriers that pass through the digestive system effectively without sinking or breaking up to the absorption site These nanodrops carry the phytosterols to the large micelles that the body produces from the bile acid where they compete with cholesterol for entry into the micelle The phytosterols enter the micelle thereby inhibiting transportation of cholesterol from the digestive system into the bloodstreamrdquo Shemen Industries

Functional food components ndash Phytosterols

Goacutemez-Guilleacuten M C B Gimeacutenez et al (2011) Functional and bioactive properties of collagen and gelatin from alternative sources A review Food Hydrocolloids 25(8) 1813-1827

Functional food components ndash Bioactive peptides

httpwwwnuritascomscreening-mining-food-for-bioactive-peptides

Health and nutrition benefits associated with Fibregum its fermentation in the large bowel increases levels of beneficial bacteria which stimulates the production of short-chain fatty acids (SCFAs) that have such properties as lowering serum cholesterol it is a strong prebiotic helping to balance the intestinal microbial ecosystem in the distal colon

Functional food components ndash Prebiotic fiber

httpwwwnexiracomFibregumE284A2-healthy-prebiotic-fiber_6html

Senegalia senegal (acacia)

Functional food components ndash Essential minerals (Fe Zn Ca Se)

httpwwwfdagovFoodGuidanceRegulationGuidanceDocumentsRegulatoryInformationLabelingNutritionucm152626htm

Pseudocereals are considered an important energy source due to their starch content they also provide good quality protein dietary fibre and lipids rich in unsaturated fats They contain adequate levels of minerals and vitamins and significant amounts of other bioactive components such as saponins phytosterols squalene fagopyritols and polyphenols

Functional food components ndash micronutrients

httpquinuapewp-contentuploads201302antiox-Gallagherpdf

Seven-step process would ensure that functional foods are safe and effective with health claims that are accurate and regulatory oversight that is science based and efficient

Functional foods

FERGUS CLYDESDALE 2004 Functional Foods Opportunities amp Challenges Food Technology December 2004 Volume 58 No12

httpwwwgooglecompatentsUS20100196569

httpwwwgooglecompatentsWO2006048158A1cl=en

httpswwwgooglecompatentsUS6428824pg=PA2ampdq=Lepidium+peruvianumamphl=enampsa=Xampei=KxK2UanpKvOu4AOehICgDwampved=0CDoQ6AEwATgK

httpswwwgooglecompatentsUS7005148pg=PA3ampdq=vaccinium+corymbosumamphl=enampsa=Xampei=-xK2UZ7vF_a64AO0soG4Cgampsqi=2amppjf=1ampved=0CGwQ6AEwCA

httpswwwgooglecompatentsWO2001045648A2cl=enampdq=vaccinium+corymbosumamphl=enampsa=Xampei=9BO2Uc_5A9Sz4AOrsIEIampved=0CDQQ6AEwAA

Potential for future researchhellip

Top health issues consumers are concerned about preventing From NMI(2005)

A ELIZABETH SLOAN 2006 Top 10 Functional Food Trends Food Technology Volume 60 No 4

Microorganisms ndash ingredients production

Citric acid

ldquoCultures of A niger are fed on a sucrose or glucose-containing medium to produce citric acid The source of sugar is corn steep liquor molasses hydrolyzed corn starch or other inexpensive sugary solutionsrdquo

httpgenomejgi-psforgAspni5Aspni5homehtml

Microorganisms ndash ingredients production

Bacillus subtilis has been genetically modified to both increase the bacterias production of riboflavin and to introduce an antibiotic (ampicillin) resistance marker wwwwikipediaorg

Riboflavin (Vitamin B2)

httpwwwocrawdogcomcat-chickenhtm

Colored scanning electron micrographs of representative cheese starter (A-C) and nonstarter (D-F) lactic acid bacteria (LAB) Lactobacillus helveticus (A) Lb delbrueckii subsp bulgaricus (B) Lactococcus lactis (C) Lb casei (D) Pediococcus pentosaceus (E) and Lb brevis (F)

Cheese

Microorganisms ndash fermented products

Microorganisms ndash fermented products

McSweeney P(2004) Biochemistry of cheese ripening Vol 57 (2-3) Int J Dairy Technol

Cheese_ Emmental

Microorganisms ndash fermented products

ldquoIn the late stage of cheese production P freudenreichii consumes the lactic acid excreted by the other bacteria and releases carbon dioxide gas which slowly forms the bubbles that make holesrdquo wwwwikipediaorg

Streptococcus thermophilus Lactobacillus debrueckii helveticus and Propionibacterium freudenreichii

Cheese_ Gouda

Microorganisms ndash fermented products

Lactococcus lactis ssp cremoris lactis Leuconostoc mesenteroides ssp cremoris

Leuconostoc mesenteroides ssp cremoris are starter cultures used for flavor and aroma development through the production of diacetyl from citrate

Roquefort

Microorganisms ndash fermented products

Camembert

ldquoPenicillium roqueforti and Penicillium caseicolum possess very potent proteolytic systems The molds secrete acid and neutral metalloproteinases and several aminopeptidases and carboxypeptidases The mycelia also contain intracellular proteinases and peptidases that are probably released when the mould dies and lysesrdquo

Microorganisms ndash fermented products

Fermented milks

Microorganisms ndash fermented products

Fermented milks

ldquoKefir grains are a combination of bacteria and yeasts in a matrix of proteins lipids and sugars and this symbiotic matrix forms grains that resemble cauliflower For this reason a complex and highly variable community of lactic acid bacteria and yeasts can be found in these grainsrdquo wwwwikipediaorg

Genus Lactobacillus Leuconostoc Pediococcus Streptococcus Bifidobacerium

Microorganisms ndash fermented products Fermented meats

Hutkins Robert W Microbiology and Technology of Fermented Foods

Pediococcus pentosaceus

httpbiowebusueduemlabcurrent20newshtml

Microorganisms ndash fermented products

Meat cultures

Lactobacillus sakei 10000-times magnified (Bild Joumlrg Groth Blessing Biotech GmbH)

Lactobacillus curvatus Lactobacillus plantarum Lactobacillus pentosus Streptococcus carnosus Micrococcus varians

httpwwwwzwtumdeindexphpid=185ampL=1amptx_ttnews5Btt_news5D=280

Microorganisms ndash fermented products

Meat cultures

httpwwwchr-hansencomproductsproduct-areasmeat-cultureshtml

Microorganisms ndash fermented products

Salami

ldquoPenicillium nalgiovense P chrysogenum and P camenberti used as starters The mold is desired as it imparts flavor helps the drying process prevents spoilage (mainly preventing growth of other mycotoxin-producing moulds during the curing process) and give a typical white color on the surfacerdquo

Microorganisms ndash fermented products

Wine amp Beer

Microorganisms ndash fermented products

Wine amp Beer

ldquoDuring fermentation the yeast converts the sugar in the wort to alcohol and carbon dioxide in addition to small amounts of glycerol and acetic acidrdquo

Yeast of the species Saccharomyces cerevisiae

httpenwikipediaorgwikiYeast

Microorganisms ndash other fermented products

httpwwwpsmicrographscoukrhizopus-mould--rhizopus-oligosporus-science-image80012871

Tempeh

Tempeh is manufactured from soaked boiled and dired soybeans that are inoculated with mold spores of species of Rhizopus (R stolonifer R oryzae R oigosporus or R arrhizus) The mash is packed or rolled in banana leaves and then incubated until there is good growth of mycelium but little sporulation Machve KK Fermentation Technology 2009

Functional food components

Critical Reviews in Food Science and Nutrition Structural Design Principles for Delivery of Bioactive Components in Nutraceuticals and Functional Foods 2011 McClements J Andrew E Yeonhwa D amp Weiss J

BioBest Omega 3 probiotic yogurt is a source of omega-3 PUFA that are considered an important part of a healthy diet It also contains over 1 billion active probiotic cultures Lactobacillus acidophilus NCFM Bifidobacterium lactis Bi-07 per serving that contribute to healthy digestive tract flora httpwwwastrocaproductsbiobest_omega_3_12x100g_multipackUbJJb_nVA8s

Functional food components ndash Omega 3

Inhibition of β-carotene degradation in oil-in-water nanoemulsions Influence of oil-soluble and water-soluble antioxidants Cheng Qian Eric Andrew Decker Hang Xiao David Julian McClements Volume 135 Issue 3 1 December 2012 Pages 1036ndash1043

Functional food components ndash Carotenoids

β-carotene enriched oil-in-water nanoemulsions stabilized by different emulsifiers with either no antioxidants (control) or antioxidants (80 μM EDTA + 10000 ppm vitamin E acetate)

Functional food components ndash Polyphenols

Pomegranate Phenolics from the Peels Arils and Flowers Are Antiatherogenic Studies in Vivo in Atherosclerotic Apolipoprotein E-Deficient (E0) Mice and in Vitro in Cultured Macrophages and Lipoproteins J Agric Food Chem 2008 56 (3) pp 1148ndash1157

Pomegranate phenolics and mainly oligomers punicalagin punicalin and gallic and ellagic acids are major contributors to the beneficial effects of pomegranate juice

Functional food components ndash Antioxidant activity

J Med Food 2012 Nov15(11)968-73 doi 101089jmf20122282 Epub 2012 Oct 12 Prickly pear cactus (Opuntia ficus indica var saboten) protects against stress-induced acute gastric lesions in rats (maltodextrin y betanin)

httpcancerpreventionresearchaacrjournalsorgcontentearly200906191940-6207CAPR-08-0167abstract

Tea Polyphenols Decrease Serum Levels of Prostate-Specific Antigen Hepatocyte Growth Factor and Vascular Endothelial Growth Factor in Prostate Cancer Patients and Inhibit Production of Hepatocyte Growth Factor and Vascular Endothelial Growth Factor In vitro 2008 Jerry McLarty Rebecca LH Bigelow Mylinh Smith Don Elmajian Murali Ankem James A Cardelli

Functional food components ndash Polyphenols

ldquoNano-sized self assembled structured liquids = nanodrops Liquid carriers that pass through the digestive system effectively without sinking or breaking up to the absorption site These nanodrops carry the phytosterols to the large micelles that the body produces from the bile acid where they compete with cholesterol for entry into the micelle The phytosterols enter the micelle thereby inhibiting transportation of cholesterol from the digestive system into the bloodstreamrdquo Shemen Industries

Functional food components ndash Phytosterols

Goacutemez-Guilleacuten M C B Gimeacutenez et al (2011) Functional and bioactive properties of collagen and gelatin from alternative sources A review Food Hydrocolloids 25(8) 1813-1827

Functional food components ndash Bioactive peptides

httpwwwnuritascomscreening-mining-food-for-bioactive-peptides

Health and nutrition benefits associated with Fibregum its fermentation in the large bowel increases levels of beneficial bacteria which stimulates the production of short-chain fatty acids (SCFAs) that have such properties as lowering serum cholesterol it is a strong prebiotic helping to balance the intestinal microbial ecosystem in the distal colon

Functional food components ndash Prebiotic fiber

httpwwwnexiracomFibregumE284A2-healthy-prebiotic-fiber_6html

Senegalia senegal (acacia)

Functional food components ndash Essential minerals (Fe Zn Ca Se)

httpwwwfdagovFoodGuidanceRegulationGuidanceDocumentsRegulatoryInformationLabelingNutritionucm152626htm

Pseudocereals are considered an important energy source due to their starch content they also provide good quality protein dietary fibre and lipids rich in unsaturated fats They contain adequate levels of minerals and vitamins and significant amounts of other bioactive components such as saponins phytosterols squalene fagopyritols and polyphenols

Functional food components ndash micronutrients

httpquinuapewp-contentuploads201302antiox-Gallagherpdf

Seven-step process would ensure that functional foods are safe and effective with health claims that are accurate and regulatory oversight that is science based and efficient

Functional foods

FERGUS CLYDESDALE 2004 Functional Foods Opportunities amp Challenges Food Technology December 2004 Volume 58 No12

httpwwwgooglecompatentsUS20100196569

httpwwwgooglecompatentsWO2006048158A1cl=en

httpswwwgooglecompatentsUS6428824pg=PA2ampdq=Lepidium+peruvianumamphl=enampsa=Xampei=KxK2UanpKvOu4AOehICgDwampved=0CDoQ6AEwATgK

httpswwwgooglecompatentsUS7005148pg=PA3ampdq=vaccinium+corymbosumamphl=enampsa=Xampei=-xK2UZ7vF_a64AO0soG4Cgampsqi=2amppjf=1ampved=0CGwQ6AEwCA

httpswwwgooglecompatentsWO2001045648A2cl=enampdq=vaccinium+corymbosumamphl=enampsa=Xampei=9BO2Uc_5A9Sz4AOrsIEIampved=0CDQQ6AEwAA

Potential for future researchhellip

Top health issues consumers are concerned about preventing From NMI(2005)

A ELIZABETH SLOAN 2006 Top 10 Functional Food Trends Food Technology Volume 60 No 4

Microorganisms ndash ingredients production

Bacillus subtilis has been genetically modified to both increase the bacterias production of riboflavin and to introduce an antibiotic (ampicillin) resistance marker wwwwikipediaorg

Riboflavin (Vitamin B2)

httpwwwocrawdogcomcat-chickenhtm

Colored scanning electron micrographs of representative cheese starter (A-C) and nonstarter (D-F) lactic acid bacteria (LAB) Lactobacillus helveticus (A) Lb delbrueckii subsp bulgaricus (B) Lactococcus lactis (C) Lb casei (D) Pediococcus pentosaceus (E) and Lb brevis (F)

Cheese

Microorganisms ndash fermented products

Microorganisms ndash fermented products

McSweeney P(2004) Biochemistry of cheese ripening Vol 57 (2-3) Int J Dairy Technol

Cheese_ Emmental

Microorganisms ndash fermented products

ldquoIn the late stage of cheese production P freudenreichii consumes the lactic acid excreted by the other bacteria and releases carbon dioxide gas which slowly forms the bubbles that make holesrdquo wwwwikipediaorg

Streptococcus thermophilus Lactobacillus debrueckii helveticus and Propionibacterium freudenreichii

Cheese_ Gouda

Microorganisms ndash fermented products

Lactococcus lactis ssp cremoris lactis Leuconostoc mesenteroides ssp cremoris

Leuconostoc mesenteroides ssp cremoris are starter cultures used for flavor and aroma development through the production of diacetyl from citrate

Roquefort

Microorganisms ndash fermented products

Camembert

ldquoPenicillium roqueforti and Penicillium caseicolum possess very potent proteolytic systems The molds secrete acid and neutral metalloproteinases and several aminopeptidases and carboxypeptidases The mycelia also contain intracellular proteinases and peptidases that are probably released when the mould dies and lysesrdquo

Microorganisms ndash fermented products

Fermented milks

Microorganisms ndash fermented products

Fermented milks

ldquoKefir grains are a combination of bacteria and yeasts in a matrix of proteins lipids and sugars and this symbiotic matrix forms grains that resemble cauliflower For this reason a complex and highly variable community of lactic acid bacteria and yeasts can be found in these grainsrdquo wwwwikipediaorg

Genus Lactobacillus Leuconostoc Pediococcus Streptococcus Bifidobacerium

Microorganisms ndash fermented products Fermented meats

Hutkins Robert W Microbiology and Technology of Fermented Foods

Pediococcus pentosaceus

httpbiowebusueduemlabcurrent20newshtml

Microorganisms ndash fermented products

Meat cultures

Lactobacillus sakei 10000-times magnified (Bild Joumlrg Groth Blessing Biotech GmbH)

Lactobacillus curvatus Lactobacillus plantarum Lactobacillus pentosus Streptococcus carnosus Micrococcus varians

httpwwwwzwtumdeindexphpid=185ampL=1amptx_ttnews5Btt_news5D=280

Microorganisms ndash fermented products

Meat cultures

httpwwwchr-hansencomproductsproduct-areasmeat-cultureshtml

Microorganisms ndash fermented products

Salami

ldquoPenicillium nalgiovense P chrysogenum and P camenberti used as starters The mold is desired as it imparts flavor helps the drying process prevents spoilage (mainly preventing growth of other mycotoxin-producing moulds during the curing process) and give a typical white color on the surfacerdquo

Microorganisms ndash fermented products

Wine amp Beer

Microorganisms ndash fermented products

Wine amp Beer

ldquoDuring fermentation the yeast converts the sugar in the wort to alcohol and carbon dioxide in addition to small amounts of glycerol and acetic acidrdquo

Yeast of the species Saccharomyces cerevisiae

httpenwikipediaorgwikiYeast

Microorganisms ndash other fermented products

httpwwwpsmicrographscoukrhizopus-mould--rhizopus-oligosporus-science-image80012871

Tempeh

Tempeh is manufactured from soaked boiled and dired soybeans that are inoculated with mold spores of species of Rhizopus (R stolonifer R oryzae R oigosporus or R arrhizus) The mash is packed or rolled in banana leaves and then incubated until there is good growth of mycelium but little sporulation Machve KK Fermentation Technology 2009

Functional food components

Critical Reviews in Food Science and Nutrition Structural Design Principles for Delivery of Bioactive Components in Nutraceuticals and Functional Foods 2011 McClements J Andrew E Yeonhwa D amp Weiss J

BioBest Omega 3 probiotic yogurt is a source of omega-3 PUFA that are considered an important part of a healthy diet It also contains over 1 billion active probiotic cultures Lactobacillus acidophilus NCFM Bifidobacterium lactis Bi-07 per serving that contribute to healthy digestive tract flora httpwwwastrocaproductsbiobest_omega_3_12x100g_multipackUbJJb_nVA8s

Functional food components ndash Omega 3

Inhibition of β-carotene degradation in oil-in-water nanoemulsions Influence of oil-soluble and water-soluble antioxidants Cheng Qian Eric Andrew Decker Hang Xiao David Julian McClements Volume 135 Issue 3 1 December 2012 Pages 1036ndash1043

Functional food components ndash Carotenoids

β-carotene enriched oil-in-water nanoemulsions stabilized by different emulsifiers with either no antioxidants (control) or antioxidants (80 μM EDTA + 10000 ppm vitamin E acetate)

Functional food components ndash Polyphenols

Pomegranate Phenolics from the Peels Arils and Flowers Are Antiatherogenic Studies in Vivo in Atherosclerotic Apolipoprotein E-Deficient (E0) Mice and in Vitro in Cultured Macrophages and Lipoproteins J Agric Food Chem 2008 56 (3) pp 1148ndash1157

Pomegranate phenolics and mainly oligomers punicalagin punicalin and gallic and ellagic acids are major contributors to the beneficial effects of pomegranate juice

Functional food components ndash Antioxidant activity

J Med Food 2012 Nov15(11)968-73 doi 101089jmf20122282 Epub 2012 Oct 12 Prickly pear cactus (Opuntia ficus indica var saboten) protects against stress-induced acute gastric lesions in rats (maltodextrin y betanin)

httpcancerpreventionresearchaacrjournalsorgcontentearly200906191940-6207CAPR-08-0167abstract

Tea Polyphenols Decrease Serum Levels of Prostate-Specific Antigen Hepatocyte Growth Factor and Vascular Endothelial Growth Factor in Prostate Cancer Patients and Inhibit Production of Hepatocyte Growth Factor and Vascular Endothelial Growth Factor In vitro 2008 Jerry McLarty Rebecca LH Bigelow Mylinh Smith Don Elmajian Murali Ankem James A Cardelli

Functional food components ndash Polyphenols

ldquoNano-sized self assembled structured liquids = nanodrops Liquid carriers that pass through the digestive system effectively without sinking or breaking up to the absorption site These nanodrops carry the phytosterols to the large micelles that the body produces from the bile acid where they compete with cholesterol for entry into the micelle The phytosterols enter the micelle thereby inhibiting transportation of cholesterol from the digestive system into the bloodstreamrdquo Shemen Industries

Functional food components ndash Phytosterols

Goacutemez-Guilleacuten M C B Gimeacutenez et al (2011) Functional and bioactive properties of collagen and gelatin from alternative sources A review Food Hydrocolloids 25(8) 1813-1827

Functional food components ndash Bioactive peptides

httpwwwnuritascomscreening-mining-food-for-bioactive-peptides

Health and nutrition benefits associated with Fibregum its fermentation in the large bowel increases levels of beneficial bacteria which stimulates the production of short-chain fatty acids (SCFAs) that have such properties as lowering serum cholesterol it is a strong prebiotic helping to balance the intestinal microbial ecosystem in the distal colon

Functional food components ndash Prebiotic fiber

httpwwwnexiracomFibregumE284A2-healthy-prebiotic-fiber_6html

Senegalia senegal (acacia)

Functional food components ndash Essential minerals (Fe Zn Ca Se)

httpwwwfdagovFoodGuidanceRegulationGuidanceDocumentsRegulatoryInformationLabelingNutritionucm152626htm

Pseudocereals are considered an important energy source due to their starch content they also provide good quality protein dietary fibre and lipids rich in unsaturated fats They contain adequate levels of minerals and vitamins and significant amounts of other bioactive components such as saponins phytosterols squalene fagopyritols and polyphenols

Functional food components ndash micronutrients

httpquinuapewp-contentuploads201302antiox-Gallagherpdf

Seven-step process would ensure that functional foods are safe and effective with health claims that are accurate and regulatory oversight that is science based and efficient

Functional foods

FERGUS CLYDESDALE 2004 Functional Foods Opportunities amp Challenges Food Technology December 2004 Volume 58 No12

httpwwwgooglecompatentsUS20100196569

httpwwwgooglecompatentsWO2006048158A1cl=en

httpswwwgooglecompatentsUS6428824pg=PA2ampdq=Lepidium+peruvianumamphl=enampsa=Xampei=KxK2UanpKvOu4AOehICgDwampved=0CDoQ6AEwATgK

httpswwwgooglecompatentsUS7005148pg=PA3ampdq=vaccinium+corymbosumamphl=enampsa=Xampei=-xK2UZ7vF_a64AO0soG4Cgampsqi=2amppjf=1ampved=0CGwQ6AEwCA

httpswwwgooglecompatentsWO2001045648A2cl=enampdq=vaccinium+corymbosumamphl=enampsa=Xampei=9BO2Uc_5A9Sz4AOrsIEIampved=0CDQQ6AEwAA

Potential for future researchhellip

Top health issues consumers are concerned about preventing From NMI(2005)

A ELIZABETH SLOAN 2006 Top 10 Functional Food Trends Food Technology Volume 60 No 4

Colored scanning electron micrographs of representative cheese starter (A-C) and nonstarter (D-F) lactic acid bacteria (LAB) Lactobacillus helveticus (A) Lb delbrueckii subsp bulgaricus (B) Lactococcus lactis (C) Lb casei (D) Pediococcus pentosaceus (E) and Lb brevis (F)

Cheese

Microorganisms ndash fermented products

Microorganisms ndash fermented products

McSweeney P(2004) Biochemistry of cheese ripening Vol 57 (2-3) Int J Dairy Technol

Cheese_ Emmental

Microorganisms ndash fermented products

ldquoIn the late stage of cheese production P freudenreichii consumes the lactic acid excreted by the other bacteria and releases carbon dioxide gas which slowly forms the bubbles that make holesrdquo wwwwikipediaorg

Streptococcus thermophilus Lactobacillus debrueckii helveticus and Propionibacterium freudenreichii

Cheese_ Gouda

Microorganisms ndash fermented products

Lactococcus lactis ssp cremoris lactis Leuconostoc mesenteroides ssp cremoris

Leuconostoc mesenteroides ssp cremoris are starter cultures used for flavor and aroma development through the production of diacetyl from citrate

Roquefort

Microorganisms ndash fermented products

Camembert

ldquoPenicillium roqueforti and Penicillium caseicolum possess very potent proteolytic systems The molds secrete acid and neutral metalloproteinases and several aminopeptidases and carboxypeptidases The mycelia also contain intracellular proteinases and peptidases that are probably released when the mould dies and lysesrdquo

Microorganisms ndash fermented products

Fermented milks

Microorganisms ndash fermented products

Fermented milks

ldquoKefir grains are a combination of bacteria and yeasts in a matrix of proteins lipids and sugars and this symbiotic matrix forms grains that resemble cauliflower For this reason a complex and highly variable community of lactic acid bacteria and yeasts can be found in these grainsrdquo wwwwikipediaorg

Genus Lactobacillus Leuconostoc Pediococcus Streptococcus Bifidobacerium

Microorganisms ndash fermented products Fermented meats

Hutkins Robert W Microbiology and Technology of Fermented Foods

Pediococcus pentosaceus

httpbiowebusueduemlabcurrent20newshtml

Microorganisms ndash fermented products

Meat cultures

Lactobacillus sakei 10000-times magnified (Bild Joumlrg Groth Blessing Biotech GmbH)

Lactobacillus curvatus Lactobacillus plantarum Lactobacillus pentosus Streptococcus carnosus Micrococcus varians

httpwwwwzwtumdeindexphpid=185ampL=1amptx_ttnews5Btt_news5D=280

Microorganisms ndash fermented products

Meat cultures

httpwwwchr-hansencomproductsproduct-areasmeat-cultureshtml

Microorganisms ndash fermented products

Salami

ldquoPenicillium nalgiovense P chrysogenum and P camenberti used as starters The mold is desired as it imparts flavor helps the drying process prevents spoilage (mainly preventing growth of other mycotoxin-producing moulds during the curing process) and give a typical white color on the surfacerdquo

Microorganisms ndash fermented products

Wine amp Beer

Microorganisms ndash fermented products

Wine amp Beer

ldquoDuring fermentation the yeast converts the sugar in the wort to alcohol and carbon dioxide in addition to small amounts of glycerol and acetic acidrdquo

Yeast of the species Saccharomyces cerevisiae

httpenwikipediaorgwikiYeast

Microorganisms ndash other fermented products

httpwwwpsmicrographscoukrhizopus-mould--rhizopus-oligosporus-science-image80012871

Tempeh

Tempeh is manufactured from soaked boiled and dired soybeans that are inoculated with mold spores of species of Rhizopus (R stolonifer R oryzae R oigosporus or R arrhizus) The mash is packed or rolled in banana leaves and then incubated until there is good growth of mycelium but little sporulation Machve KK Fermentation Technology 2009

Functional food components

Critical Reviews in Food Science and Nutrition Structural Design Principles for Delivery of Bioactive Components in Nutraceuticals and Functional Foods 2011 McClements J Andrew E Yeonhwa D amp Weiss J

BioBest Omega 3 probiotic yogurt is a source of omega-3 PUFA that are considered an important part of a healthy diet It also contains over 1 billion active probiotic cultures Lactobacillus acidophilus NCFM Bifidobacterium lactis Bi-07 per serving that contribute to healthy digestive tract flora httpwwwastrocaproductsbiobest_omega_3_12x100g_multipackUbJJb_nVA8s

Functional food components ndash Omega 3

Inhibition of β-carotene degradation in oil-in-water nanoemulsions Influence of oil-soluble and water-soluble antioxidants Cheng Qian Eric Andrew Decker Hang Xiao David Julian McClements Volume 135 Issue 3 1 December 2012 Pages 1036ndash1043

Functional food components ndash Carotenoids

β-carotene enriched oil-in-water nanoemulsions stabilized by different emulsifiers with either no antioxidants (control) or antioxidants (80 μM EDTA + 10000 ppm vitamin E acetate)

Functional food components ndash Polyphenols

Pomegranate Phenolics from the Peels Arils and Flowers Are Antiatherogenic Studies in Vivo in Atherosclerotic Apolipoprotein E-Deficient (E0) Mice and in Vitro in Cultured Macrophages and Lipoproteins J Agric Food Chem 2008 56 (3) pp 1148ndash1157

Pomegranate phenolics and mainly oligomers punicalagin punicalin and gallic and ellagic acids are major contributors to the beneficial effects of pomegranate juice

Functional food components ndash Antioxidant activity

J Med Food 2012 Nov15(11)968-73 doi 101089jmf20122282 Epub 2012 Oct 12 Prickly pear cactus (Opuntia ficus indica var saboten) protects against stress-induced acute gastric lesions in rats (maltodextrin y betanin)

httpcancerpreventionresearchaacrjournalsorgcontentearly200906191940-6207CAPR-08-0167abstract

Tea Polyphenols Decrease Serum Levels of Prostate-Specific Antigen Hepatocyte Growth Factor and Vascular Endothelial Growth Factor in Prostate Cancer Patients and Inhibit Production of Hepatocyte Growth Factor and Vascular Endothelial Growth Factor In vitro 2008 Jerry McLarty Rebecca LH Bigelow Mylinh Smith Don Elmajian Murali Ankem James A Cardelli

Functional food components ndash Polyphenols

ldquoNano-sized self assembled structured liquids = nanodrops Liquid carriers that pass through the digestive system effectively without sinking or breaking up to the absorption site These nanodrops carry the phytosterols to the large micelles that the body produces from the bile acid where they compete with cholesterol for entry into the micelle The phytosterols enter the micelle thereby inhibiting transportation of cholesterol from the digestive system into the bloodstreamrdquo Shemen Industries

Functional food components ndash Phytosterols

Goacutemez-Guilleacuten M C B Gimeacutenez et al (2011) Functional and bioactive properties of collagen and gelatin from alternative sources A review Food Hydrocolloids 25(8) 1813-1827

Functional food components ndash Bioactive peptides

httpwwwnuritascomscreening-mining-food-for-bioactive-peptides

Health and nutrition benefits associated with Fibregum its fermentation in the large bowel increases levels of beneficial bacteria which stimulates the production of short-chain fatty acids (SCFAs) that have such properties as lowering serum cholesterol it is a strong prebiotic helping to balance the intestinal microbial ecosystem in the distal colon

Functional food components ndash Prebiotic fiber

httpwwwnexiracomFibregumE284A2-healthy-prebiotic-fiber_6html

Senegalia senegal (acacia)

Functional food components ndash Essential minerals (Fe Zn Ca Se)

httpwwwfdagovFoodGuidanceRegulationGuidanceDocumentsRegulatoryInformationLabelingNutritionucm152626htm

Pseudocereals are considered an important energy source due to their starch content they also provide good quality protein dietary fibre and lipids rich in unsaturated fats They contain adequate levels of minerals and vitamins and significant amounts of other bioactive components such as saponins phytosterols squalene fagopyritols and polyphenols

Functional food components ndash micronutrients

httpquinuapewp-contentuploads201302antiox-Gallagherpdf

Seven-step process would ensure that functional foods are safe and effective with health claims that are accurate and regulatory oversight that is science based and efficient

Functional foods

FERGUS CLYDESDALE 2004 Functional Foods Opportunities amp Challenges Food Technology December 2004 Volume 58 No12

httpwwwgooglecompatentsUS20100196569

httpwwwgooglecompatentsWO2006048158A1cl=en

httpswwwgooglecompatentsUS6428824pg=PA2ampdq=Lepidium+peruvianumamphl=enampsa=Xampei=KxK2UanpKvOu4AOehICgDwampved=0CDoQ6AEwATgK

httpswwwgooglecompatentsUS7005148pg=PA3ampdq=vaccinium+corymbosumamphl=enampsa=Xampei=-xK2UZ7vF_a64AO0soG4Cgampsqi=2amppjf=1ampved=0CGwQ6AEwCA

httpswwwgooglecompatentsWO2001045648A2cl=enampdq=vaccinium+corymbosumamphl=enampsa=Xampei=9BO2Uc_5A9Sz4AOrsIEIampved=0CDQQ6AEwAA

Potential for future researchhellip

Top health issues consumers are concerned about preventing From NMI(2005)

A ELIZABETH SLOAN 2006 Top 10 Functional Food Trends Food Technology Volume 60 No 4

Microorganisms ndash fermented products

McSweeney P(2004) Biochemistry of cheese ripening Vol 57 (2-3) Int J Dairy Technol

Cheese_ Emmental

Microorganisms ndash fermented products

ldquoIn the late stage of cheese production P freudenreichii consumes the lactic acid excreted by the other bacteria and releases carbon dioxide gas which slowly forms the bubbles that make holesrdquo wwwwikipediaorg

Streptococcus thermophilus Lactobacillus debrueckii helveticus and Propionibacterium freudenreichii

Cheese_ Gouda

Microorganisms ndash fermented products

Lactococcus lactis ssp cremoris lactis Leuconostoc mesenteroides ssp cremoris

Leuconostoc mesenteroides ssp cremoris are starter cultures used for flavor and aroma development through the production of diacetyl from citrate

Roquefort

Microorganisms ndash fermented products

Camembert

ldquoPenicillium roqueforti and Penicillium caseicolum possess very potent proteolytic systems The molds secrete acid and neutral metalloproteinases and several aminopeptidases and carboxypeptidases The mycelia also contain intracellular proteinases and peptidases that are probably released when the mould dies and lysesrdquo

Microorganisms ndash fermented products

Fermented milks

Microorganisms ndash fermented products

Fermented milks

ldquoKefir grains are a combination of bacteria and yeasts in a matrix of proteins lipids and sugars and this symbiotic matrix forms grains that resemble cauliflower For this reason a complex and highly variable community of lactic acid bacteria and yeasts can be found in these grainsrdquo wwwwikipediaorg

Genus Lactobacillus Leuconostoc Pediococcus Streptococcus Bifidobacerium

Microorganisms ndash fermented products Fermented meats

Hutkins Robert W Microbiology and Technology of Fermented Foods

Pediococcus pentosaceus

httpbiowebusueduemlabcurrent20newshtml

Microorganisms ndash fermented products

Meat cultures

Lactobacillus sakei 10000-times magnified (Bild Joumlrg Groth Blessing Biotech GmbH)

Lactobacillus curvatus Lactobacillus plantarum Lactobacillus pentosus Streptococcus carnosus Micrococcus varians

httpwwwwzwtumdeindexphpid=185ampL=1amptx_ttnews5Btt_news5D=280

Microorganisms ndash fermented products

Meat cultures

httpwwwchr-hansencomproductsproduct-areasmeat-cultureshtml

Microorganisms ndash fermented products

Salami

ldquoPenicillium nalgiovense P chrysogenum and P camenberti used as starters The mold is desired as it imparts flavor helps the drying process prevents spoilage (mainly preventing growth of other mycotoxin-producing moulds during the curing process) and give a typical white color on the surfacerdquo

Microorganisms ndash fermented products

Wine amp Beer

Microorganisms ndash fermented products

Wine amp Beer

ldquoDuring fermentation the yeast converts the sugar in the wort to alcohol and carbon dioxide in addition to small amounts of glycerol and acetic acidrdquo

Yeast of the species Saccharomyces cerevisiae

httpenwikipediaorgwikiYeast

Microorganisms ndash other fermented products

httpwwwpsmicrographscoukrhizopus-mould--rhizopus-oligosporus-science-image80012871

Tempeh

Tempeh is manufactured from soaked boiled and dired soybeans that are inoculated with mold spores of species of Rhizopus (R stolonifer R oryzae R oigosporus or R arrhizus) The mash is packed or rolled in banana leaves and then incubated until there is good growth of mycelium but little sporulation Machve KK Fermentation Technology 2009

Functional food components

Critical Reviews in Food Science and Nutrition Structural Design Principles for Delivery of Bioactive Components in Nutraceuticals and Functional Foods 2011 McClements J Andrew E Yeonhwa D amp Weiss J

BioBest Omega 3 probiotic yogurt is a source of omega-3 PUFA that are considered an important part of a healthy diet It also contains over 1 billion active probiotic cultures Lactobacillus acidophilus NCFM Bifidobacterium lactis Bi-07 per serving that contribute to healthy digestive tract flora httpwwwastrocaproductsbiobest_omega_3_12x100g_multipackUbJJb_nVA8s

Functional food components ndash Omega 3

Inhibition of β-carotene degradation in oil-in-water nanoemulsions Influence of oil-soluble and water-soluble antioxidants Cheng Qian Eric Andrew Decker Hang Xiao David Julian McClements Volume 135 Issue 3 1 December 2012 Pages 1036ndash1043

Functional food components ndash Carotenoids

β-carotene enriched oil-in-water nanoemulsions stabilized by different emulsifiers with either no antioxidants (control) or antioxidants (80 μM EDTA + 10000 ppm vitamin E acetate)

Functional food components ndash Polyphenols

Pomegranate Phenolics from the Peels Arils and Flowers Are Antiatherogenic Studies in Vivo in Atherosclerotic Apolipoprotein E-Deficient (E0) Mice and in Vitro in Cultured Macrophages and Lipoproteins J Agric Food Chem 2008 56 (3) pp 1148ndash1157

Pomegranate phenolics and mainly oligomers punicalagin punicalin and gallic and ellagic acids are major contributors to the beneficial effects of pomegranate juice

Functional food components ndash Antioxidant activity

J Med Food 2012 Nov15(11)968-73 doi 101089jmf20122282 Epub 2012 Oct 12 Prickly pear cactus (Opuntia ficus indica var saboten) protects against stress-induced acute gastric lesions in rats (maltodextrin y betanin)

httpcancerpreventionresearchaacrjournalsorgcontentearly200906191940-6207CAPR-08-0167abstract

Tea Polyphenols Decrease Serum Levels of Prostate-Specific Antigen Hepatocyte Growth Factor and Vascular Endothelial Growth Factor in Prostate Cancer Patients and Inhibit Production of Hepatocyte Growth Factor and Vascular Endothelial Growth Factor In vitro 2008 Jerry McLarty Rebecca LH Bigelow Mylinh Smith Don Elmajian Murali Ankem James A Cardelli

Functional food components ndash Polyphenols

ldquoNano-sized self assembled structured liquids = nanodrops Liquid carriers that pass through the digestive system effectively without sinking or breaking up to the absorption site These nanodrops carry the phytosterols to the large micelles that the body produces from the bile acid where they compete with cholesterol for entry into the micelle The phytosterols enter the micelle thereby inhibiting transportation of cholesterol from the digestive system into the bloodstreamrdquo Shemen Industries

Functional food components ndash Phytosterols

Goacutemez-Guilleacuten M C B Gimeacutenez et al (2011) Functional and bioactive properties of collagen and gelatin from alternative sources A review Food Hydrocolloids 25(8) 1813-1827

Functional food components ndash Bioactive peptides

httpwwwnuritascomscreening-mining-food-for-bioactive-peptides

Health and nutrition benefits associated with Fibregum its fermentation in the large bowel increases levels of beneficial bacteria which stimulates the production of short-chain fatty acids (SCFAs) that have such properties as lowering serum cholesterol it is a strong prebiotic helping to balance the intestinal microbial ecosystem in the distal colon

Functional food components ndash Prebiotic fiber

httpwwwnexiracomFibregumE284A2-healthy-prebiotic-fiber_6html

Senegalia senegal (acacia)

Functional food components ndash Essential minerals (Fe Zn Ca Se)

httpwwwfdagovFoodGuidanceRegulationGuidanceDocumentsRegulatoryInformationLabelingNutritionucm152626htm

Pseudocereals are considered an important energy source due to their starch content they also provide good quality protein dietary fibre and lipids rich in unsaturated fats They contain adequate levels of minerals and vitamins and significant amounts of other bioactive components such as saponins phytosterols squalene fagopyritols and polyphenols

Functional food components ndash micronutrients

httpquinuapewp-contentuploads201302antiox-Gallagherpdf

Seven-step process would ensure that functional foods are safe and effective with health claims that are accurate and regulatory oversight that is science based and efficient

Functional foods

FERGUS CLYDESDALE 2004 Functional Foods Opportunities amp Challenges Food Technology December 2004 Volume 58 No12

httpwwwgooglecompatentsUS20100196569

httpwwwgooglecompatentsWO2006048158A1cl=en

httpswwwgooglecompatentsUS6428824pg=PA2ampdq=Lepidium+peruvianumamphl=enampsa=Xampei=KxK2UanpKvOu4AOehICgDwampved=0CDoQ6AEwATgK

httpswwwgooglecompatentsUS7005148pg=PA3ampdq=vaccinium+corymbosumamphl=enampsa=Xampei=-xK2UZ7vF_a64AO0soG4Cgampsqi=2amppjf=1ampved=0CGwQ6AEwCA

httpswwwgooglecompatentsWO2001045648A2cl=enampdq=vaccinium+corymbosumamphl=enampsa=Xampei=9BO2Uc_5A9Sz4AOrsIEIampved=0CDQQ6AEwAA

Potential for future researchhellip

Top health issues consumers are concerned about preventing From NMI(2005)

A ELIZABETH SLOAN 2006 Top 10 Functional Food Trends Food Technology Volume 60 No 4

Cheese_ Emmental

Microorganisms ndash fermented products

ldquoIn the late stage of cheese production P freudenreichii consumes the lactic acid excreted by the other bacteria and releases carbon dioxide gas which slowly forms the bubbles that make holesrdquo wwwwikipediaorg

Streptococcus thermophilus Lactobacillus debrueckii helveticus and Propionibacterium freudenreichii

Cheese_ Gouda

Microorganisms ndash fermented products

Lactococcus lactis ssp cremoris lactis Leuconostoc mesenteroides ssp cremoris

Leuconostoc mesenteroides ssp cremoris are starter cultures used for flavor and aroma development through the production of diacetyl from citrate

Roquefort

Microorganisms ndash fermented products

Camembert

ldquoPenicillium roqueforti and Penicillium caseicolum possess very potent proteolytic systems The molds secrete acid and neutral metalloproteinases and several aminopeptidases and carboxypeptidases The mycelia also contain intracellular proteinases and peptidases that are probably released when the mould dies and lysesrdquo

Microorganisms ndash fermented products

Fermented milks

Microorganisms ndash fermented products

Fermented milks

ldquoKefir grains are a combination of bacteria and yeasts in a matrix of proteins lipids and sugars and this symbiotic matrix forms grains that resemble cauliflower For this reason a complex and highly variable community of lactic acid bacteria and yeasts can be found in these grainsrdquo wwwwikipediaorg

Genus Lactobacillus Leuconostoc Pediococcus Streptococcus Bifidobacerium

Microorganisms ndash fermented products Fermented meats

Hutkins Robert W Microbiology and Technology of Fermented Foods

Pediococcus pentosaceus

httpbiowebusueduemlabcurrent20newshtml

Microorganisms ndash fermented products

Meat cultures

Lactobacillus sakei 10000-times magnified (Bild Joumlrg Groth Blessing Biotech GmbH)

Lactobacillus curvatus Lactobacillus plantarum Lactobacillus pentosus Streptococcus carnosus Micrococcus varians

httpwwwwzwtumdeindexphpid=185ampL=1amptx_ttnews5Btt_news5D=280

Microorganisms ndash fermented products

Meat cultures

httpwwwchr-hansencomproductsproduct-areasmeat-cultureshtml

Microorganisms ndash fermented products

Salami

ldquoPenicillium nalgiovense P chrysogenum and P camenberti used as starters The mold is desired as it imparts flavor helps the drying process prevents spoilage (mainly preventing growth of other mycotoxin-producing moulds during the curing process) and give a typical white color on the surfacerdquo

Microorganisms ndash fermented products

Wine amp Beer

Microorganisms ndash fermented products

Wine amp Beer

ldquoDuring fermentation the yeast converts the sugar in the wort to alcohol and carbon dioxide in addition to small amounts of glycerol and acetic acidrdquo

Yeast of the species Saccharomyces cerevisiae

httpenwikipediaorgwikiYeast

Microorganisms ndash other fermented products

httpwwwpsmicrographscoukrhizopus-mould--rhizopus-oligosporus-science-image80012871

Tempeh

Tempeh is manufactured from soaked boiled and dired soybeans that are inoculated with mold spores of species of Rhizopus (R stolonifer R oryzae R oigosporus or R arrhizus) The mash is packed or rolled in banana leaves and then incubated until there is good growth of mycelium but little sporulation Machve KK Fermentation Technology 2009

Functional food components

Critical Reviews in Food Science and Nutrition Structural Design Principles for Delivery of Bioactive Components in Nutraceuticals and Functional Foods 2011 McClements J Andrew E Yeonhwa D amp Weiss J

BioBest Omega 3 probiotic yogurt is a source of omega-3 PUFA that are considered an important part of a healthy diet It also contains over 1 billion active probiotic cultures Lactobacillus acidophilus NCFM Bifidobacterium lactis Bi-07 per serving that contribute to healthy digestive tract flora httpwwwastrocaproductsbiobest_omega_3_12x100g_multipackUbJJb_nVA8s

Functional food components ndash Omega 3

Inhibition of β-carotene degradation in oil-in-water nanoemulsions Influence of oil-soluble and water-soluble antioxidants Cheng Qian Eric Andrew Decker Hang Xiao David Julian McClements Volume 135 Issue 3 1 December 2012 Pages 1036ndash1043

Functional food components ndash Carotenoids

β-carotene enriched oil-in-water nanoemulsions stabilized by different emulsifiers with either no antioxidants (control) or antioxidants (80 μM EDTA + 10000 ppm vitamin E acetate)

Functional food components ndash Polyphenols

Pomegranate Phenolics from the Peels Arils and Flowers Are Antiatherogenic Studies in Vivo in Atherosclerotic Apolipoprotein E-Deficient (E0) Mice and in Vitro in Cultured Macrophages and Lipoproteins J Agric Food Chem 2008 56 (3) pp 1148ndash1157

Pomegranate phenolics and mainly oligomers punicalagin punicalin and gallic and ellagic acids are major contributors to the beneficial effects of pomegranate juice

Functional food components ndash Antioxidant activity

J Med Food 2012 Nov15(11)968-73 doi 101089jmf20122282 Epub 2012 Oct 12 Prickly pear cactus (Opuntia ficus indica var saboten) protects against stress-induced acute gastric lesions in rats (maltodextrin y betanin)

httpcancerpreventionresearchaacrjournalsorgcontentearly200906191940-6207CAPR-08-0167abstract

Tea Polyphenols Decrease Serum Levels of Prostate-Specific Antigen Hepatocyte Growth Factor and Vascular Endothelial Growth Factor in Prostate Cancer Patients and Inhibit Production of Hepatocyte Growth Factor and Vascular Endothelial Growth Factor In vitro 2008 Jerry McLarty Rebecca LH Bigelow Mylinh Smith Don Elmajian Murali Ankem James A Cardelli

Functional food components ndash Polyphenols

ldquoNano-sized self assembled structured liquids = nanodrops Liquid carriers that pass through the digestive system effectively without sinking or breaking up to the absorption site These nanodrops carry the phytosterols to the large micelles that the body produces from the bile acid where they compete with cholesterol for entry into the micelle The phytosterols enter the micelle thereby inhibiting transportation of cholesterol from the digestive system into the bloodstreamrdquo Shemen Industries

Functional food components ndash Phytosterols

Goacutemez-Guilleacuten M C B Gimeacutenez et al (2011) Functional and bioactive properties of collagen and gelatin from alternative sources A review Food Hydrocolloids 25(8) 1813-1827

Functional food components ndash Bioactive peptides

httpwwwnuritascomscreening-mining-food-for-bioactive-peptides

Health and nutrition benefits associated with Fibregum its fermentation in the large bowel increases levels of beneficial bacteria which stimulates the production of short-chain fatty acids (SCFAs) that have such properties as lowering serum cholesterol it is a strong prebiotic helping to balance the intestinal microbial ecosystem in the distal colon

Functional food components ndash Prebiotic fiber

httpwwwnexiracomFibregumE284A2-healthy-prebiotic-fiber_6html

Senegalia senegal (acacia)

Functional food components ndash Essential minerals (Fe Zn Ca Se)

httpwwwfdagovFoodGuidanceRegulationGuidanceDocumentsRegulatoryInformationLabelingNutritionucm152626htm

Pseudocereals are considered an important energy source due to their starch content they also provide good quality protein dietary fibre and lipids rich in unsaturated fats They contain adequate levels of minerals and vitamins and significant amounts of other bioactive components such as saponins phytosterols squalene fagopyritols and polyphenols

Functional food components ndash micronutrients

httpquinuapewp-contentuploads201302antiox-Gallagherpdf

Seven-step process would ensure that functional foods are safe and effective with health claims that are accurate and regulatory oversight that is science based and efficient

Functional foods

FERGUS CLYDESDALE 2004 Functional Foods Opportunities amp Challenges Food Technology December 2004 Volume 58 No12

httpwwwgooglecompatentsUS20100196569

httpwwwgooglecompatentsWO2006048158A1cl=en

httpswwwgooglecompatentsUS6428824pg=PA2ampdq=Lepidium+peruvianumamphl=enampsa=Xampei=KxK2UanpKvOu4AOehICgDwampved=0CDoQ6AEwATgK

httpswwwgooglecompatentsUS7005148pg=PA3ampdq=vaccinium+corymbosumamphl=enampsa=Xampei=-xK2UZ7vF_a64AO0soG4Cgampsqi=2amppjf=1ampved=0CGwQ6AEwCA

httpswwwgooglecompatentsWO2001045648A2cl=enampdq=vaccinium+corymbosumamphl=enampsa=Xampei=9BO2Uc_5A9Sz4AOrsIEIampved=0CDQQ6AEwAA

Potential for future researchhellip

Top health issues consumers are concerned about preventing From NMI(2005)

A ELIZABETH SLOAN 2006 Top 10 Functional Food Trends Food Technology Volume 60 No 4

Cheese_ Gouda

Microorganisms ndash fermented products

Lactococcus lactis ssp cremoris lactis Leuconostoc mesenteroides ssp cremoris

Leuconostoc mesenteroides ssp cremoris are starter cultures used for flavor and aroma development through the production of diacetyl from citrate

Roquefort

Microorganisms ndash fermented products

Camembert

ldquoPenicillium roqueforti and Penicillium caseicolum possess very potent proteolytic systems The molds secrete acid and neutral metalloproteinases and several aminopeptidases and carboxypeptidases The mycelia also contain intracellular proteinases and peptidases that are probably released when the mould dies and lysesrdquo

Microorganisms ndash fermented products

Fermented milks

Microorganisms ndash fermented products

Fermented milks

ldquoKefir grains are a combination of bacteria and yeasts in a matrix of proteins lipids and sugars and this symbiotic matrix forms grains that resemble cauliflower For this reason a complex and highly variable community of lactic acid bacteria and yeasts can be found in these grainsrdquo wwwwikipediaorg

Genus Lactobacillus Leuconostoc Pediococcus Streptococcus Bifidobacerium

Microorganisms ndash fermented products Fermented meats

Hutkins Robert W Microbiology and Technology of Fermented Foods

Pediococcus pentosaceus

httpbiowebusueduemlabcurrent20newshtml

Microorganisms ndash fermented products

Meat cultures

Lactobacillus sakei 10000-times magnified (Bild Joumlrg Groth Blessing Biotech GmbH)

Lactobacillus curvatus Lactobacillus plantarum Lactobacillus pentosus Streptococcus carnosus Micrococcus varians

httpwwwwzwtumdeindexphpid=185ampL=1amptx_ttnews5Btt_news5D=280

Microorganisms ndash fermented products

Meat cultures

httpwwwchr-hansencomproductsproduct-areasmeat-cultureshtml

Microorganisms ndash fermented products

Salami

ldquoPenicillium nalgiovense P chrysogenum and P camenberti used as starters The mold is desired as it imparts flavor helps the drying process prevents spoilage (mainly preventing growth of other mycotoxin-producing moulds during the curing process) and give a typical white color on the surfacerdquo

Microorganisms ndash fermented products

Wine amp Beer

Microorganisms ndash fermented products

Wine amp Beer

ldquoDuring fermentation the yeast converts the sugar in the wort to alcohol and carbon dioxide in addition to small amounts of glycerol and acetic acidrdquo

Yeast of the species Saccharomyces cerevisiae

httpenwikipediaorgwikiYeast

Microorganisms ndash other fermented products

httpwwwpsmicrographscoukrhizopus-mould--rhizopus-oligosporus-science-image80012871

Tempeh

Tempeh is manufactured from soaked boiled and dired soybeans that are inoculated with mold spores of species of Rhizopus (R stolonifer R oryzae R oigosporus or R arrhizus) The mash is packed or rolled in banana leaves and then incubated until there is good growth of mycelium but little sporulation Machve KK Fermentation Technology 2009

Functional food components

Critical Reviews in Food Science and Nutrition Structural Design Principles for Delivery of Bioactive Components in Nutraceuticals and Functional Foods 2011 McClements J Andrew E Yeonhwa D amp Weiss J

BioBest Omega 3 probiotic yogurt is a source of omega-3 PUFA that are considered an important part of a healthy diet It also contains over 1 billion active probiotic cultures Lactobacillus acidophilus NCFM Bifidobacterium lactis Bi-07 per serving that contribute to healthy digestive tract flora httpwwwastrocaproductsbiobest_omega_3_12x100g_multipackUbJJb_nVA8s

Functional food components ndash Omega 3

Inhibition of β-carotene degradation in oil-in-water nanoemulsions Influence of oil-soluble and water-soluble antioxidants Cheng Qian Eric Andrew Decker Hang Xiao David Julian McClements Volume 135 Issue 3 1 December 2012 Pages 1036ndash1043

Functional food components ndash Carotenoids

β-carotene enriched oil-in-water nanoemulsions stabilized by different emulsifiers with either no antioxidants (control) or antioxidants (80 μM EDTA + 10000 ppm vitamin E acetate)

Functional food components ndash Polyphenols

Pomegranate Phenolics from the Peels Arils and Flowers Are Antiatherogenic Studies in Vivo in Atherosclerotic Apolipoprotein E-Deficient (E0) Mice and in Vitro in Cultured Macrophages and Lipoproteins J Agric Food Chem 2008 56 (3) pp 1148ndash1157

Pomegranate phenolics and mainly oligomers punicalagin punicalin and gallic and ellagic acids are major contributors to the beneficial effects of pomegranate juice

Functional food components ndash Antioxidant activity

J Med Food 2012 Nov15(11)968-73 doi 101089jmf20122282 Epub 2012 Oct 12 Prickly pear cactus (Opuntia ficus indica var saboten) protects against stress-induced acute gastric lesions in rats (maltodextrin y betanin)

httpcancerpreventionresearchaacrjournalsorgcontentearly200906191940-6207CAPR-08-0167abstract

Tea Polyphenols Decrease Serum Levels of Prostate-Specific Antigen Hepatocyte Growth Factor and Vascular Endothelial Growth Factor in Prostate Cancer Patients and Inhibit Production of Hepatocyte Growth Factor and Vascular Endothelial Growth Factor In vitro 2008 Jerry McLarty Rebecca LH Bigelow Mylinh Smith Don Elmajian Murali Ankem James A Cardelli

Functional food components ndash Polyphenols

ldquoNano-sized self assembled structured liquids = nanodrops Liquid carriers that pass through the digestive system effectively without sinking or breaking up to the absorption site These nanodrops carry the phytosterols to the large micelles that the body produces from the bile acid where they compete with cholesterol for entry into the micelle The phytosterols enter the micelle thereby inhibiting transportation of cholesterol from the digestive system into the bloodstreamrdquo Shemen Industries

Functional food components ndash Phytosterols

Goacutemez-Guilleacuten M C B Gimeacutenez et al (2011) Functional and bioactive properties of collagen and gelatin from alternative sources A review Food Hydrocolloids 25(8) 1813-1827

Functional food components ndash Bioactive peptides

httpwwwnuritascomscreening-mining-food-for-bioactive-peptides

Health and nutrition benefits associated with Fibregum its fermentation in the large bowel increases levels of beneficial bacteria which stimulates the production of short-chain fatty acids (SCFAs) that have such properties as lowering serum cholesterol it is a strong prebiotic helping to balance the intestinal microbial ecosystem in the distal colon

Functional food components ndash Prebiotic fiber

httpwwwnexiracomFibregumE284A2-healthy-prebiotic-fiber_6html

Senegalia senegal (acacia)

Functional food components ndash Essential minerals (Fe Zn Ca Se)

httpwwwfdagovFoodGuidanceRegulationGuidanceDocumentsRegulatoryInformationLabelingNutritionucm152626htm

Pseudocereals are considered an important energy source due to their starch content they also provide good quality protein dietary fibre and lipids rich in unsaturated fats They contain adequate levels of minerals and vitamins and significant amounts of other bioactive components such as saponins phytosterols squalene fagopyritols and polyphenols

Functional food components ndash micronutrients

httpquinuapewp-contentuploads201302antiox-Gallagherpdf

Seven-step process would ensure that functional foods are safe and effective with health claims that are accurate and regulatory oversight that is science based and efficient

Functional foods

FERGUS CLYDESDALE 2004 Functional Foods Opportunities amp Challenges Food Technology December 2004 Volume 58 No12

httpwwwgooglecompatentsUS20100196569

httpwwwgooglecompatentsWO2006048158A1cl=en

httpswwwgooglecompatentsUS6428824pg=PA2ampdq=Lepidium+peruvianumamphl=enampsa=Xampei=KxK2UanpKvOu4AOehICgDwampved=0CDoQ6AEwATgK

httpswwwgooglecompatentsUS7005148pg=PA3ampdq=vaccinium+corymbosumamphl=enampsa=Xampei=-xK2UZ7vF_a64AO0soG4Cgampsqi=2amppjf=1ampved=0CGwQ6AEwCA

httpswwwgooglecompatentsWO2001045648A2cl=enampdq=vaccinium+corymbosumamphl=enampsa=Xampei=9BO2Uc_5A9Sz4AOrsIEIampved=0CDQQ6AEwAA

Potential for future researchhellip

Top health issues consumers are concerned about preventing From NMI(2005)

A ELIZABETH SLOAN 2006 Top 10 Functional Food Trends Food Technology Volume 60 No 4

Roquefort

Microorganisms ndash fermented products

Camembert

ldquoPenicillium roqueforti and Penicillium caseicolum possess very potent proteolytic systems The molds secrete acid and neutral metalloproteinases and several aminopeptidases and carboxypeptidases The mycelia also contain intracellular proteinases and peptidases that are probably released when the mould dies and lysesrdquo

Microorganisms ndash fermented products

Fermented milks

Microorganisms ndash fermented products

Fermented milks

ldquoKefir grains are a combination of bacteria and yeasts in a matrix of proteins lipids and sugars and this symbiotic matrix forms grains that resemble cauliflower For this reason a complex and highly variable community of lactic acid bacteria and yeasts can be found in these grainsrdquo wwwwikipediaorg

Genus Lactobacillus Leuconostoc Pediococcus Streptococcus Bifidobacerium

Microorganisms ndash fermented products Fermented meats

Hutkins Robert W Microbiology and Technology of Fermented Foods

Pediococcus pentosaceus

httpbiowebusueduemlabcurrent20newshtml

Microorganisms ndash fermented products

Meat cultures

Lactobacillus sakei 10000-times magnified (Bild Joumlrg Groth Blessing Biotech GmbH)

Lactobacillus curvatus Lactobacillus plantarum Lactobacillus pentosus Streptococcus carnosus Micrococcus varians

httpwwwwzwtumdeindexphpid=185ampL=1amptx_ttnews5Btt_news5D=280

Microorganisms ndash fermented products

Meat cultures

httpwwwchr-hansencomproductsproduct-areasmeat-cultureshtml

Microorganisms ndash fermented products

Salami

ldquoPenicillium nalgiovense P chrysogenum and P camenberti used as starters The mold is desired as it imparts flavor helps the drying process prevents spoilage (mainly preventing growth of other mycotoxin-producing moulds during the curing process) and give a typical white color on the surfacerdquo

Microorganisms ndash fermented products

Wine amp Beer

Microorganisms ndash fermented products

Wine amp Beer

ldquoDuring fermentation the yeast converts the sugar in the wort to alcohol and carbon dioxide in addition to small amounts of glycerol and acetic acidrdquo

Yeast of the species Saccharomyces cerevisiae

httpenwikipediaorgwikiYeast

Microorganisms ndash other fermented products

httpwwwpsmicrographscoukrhizopus-mould--rhizopus-oligosporus-science-image80012871

Tempeh

Tempeh is manufactured from soaked boiled and dired soybeans that are inoculated with mold spores of species of Rhizopus (R stolonifer R oryzae R oigosporus or R arrhizus) The mash is packed or rolled in banana leaves and then incubated until there is good growth of mycelium but little sporulation Machve KK Fermentation Technology 2009

Functional food components

Critical Reviews in Food Science and Nutrition Structural Design Principles for Delivery of Bioactive Components in Nutraceuticals and Functional Foods 2011 McClements J Andrew E Yeonhwa D amp Weiss J

BioBest Omega 3 probiotic yogurt is a source of omega-3 PUFA that are considered an important part of a healthy diet It also contains over 1 billion active probiotic cultures Lactobacillus acidophilus NCFM Bifidobacterium lactis Bi-07 per serving that contribute to healthy digestive tract flora httpwwwastrocaproductsbiobest_omega_3_12x100g_multipackUbJJb_nVA8s

Functional food components ndash Omega 3

Inhibition of β-carotene degradation in oil-in-water nanoemulsions Influence of oil-soluble and water-soluble antioxidants Cheng Qian Eric Andrew Decker Hang Xiao David Julian McClements Volume 135 Issue 3 1 December 2012 Pages 1036ndash1043

Functional food components ndash Carotenoids

β-carotene enriched oil-in-water nanoemulsions stabilized by different emulsifiers with either no antioxidants (control) or antioxidants (80 μM EDTA + 10000 ppm vitamin E acetate)

Functional food components ndash Polyphenols

Pomegranate Phenolics from the Peels Arils and Flowers Are Antiatherogenic Studies in Vivo in Atherosclerotic Apolipoprotein E-Deficient (E0) Mice and in Vitro in Cultured Macrophages and Lipoproteins J Agric Food Chem 2008 56 (3) pp 1148ndash1157

Pomegranate phenolics and mainly oligomers punicalagin punicalin and gallic and ellagic acids are major contributors to the beneficial effects of pomegranate juice

Functional food components ndash Antioxidant activity

J Med Food 2012 Nov15(11)968-73 doi 101089jmf20122282 Epub 2012 Oct 12 Prickly pear cactus (Opuntia ficus indica var saboten) protects against stress-induced acute gastric lesions in rats (maltodextrin y betanin)

httpcancerpreventionresearchaacrjournalsorgcontentearly200906191940-6207CAPR-08-0167abstract

Tea Polyphenols Decrease Serum Levels of Prostate-Specific Antigen Hepatocyte Growth Factor and Vascular Endothelial Growth Factor in Prostate Cancer Patients and Inhibit Production of Hepatocyte Growth Factor and Vascular Endothelial Growth Factor In vitro 2008 Jerry McLarty Rebecca LH Bigelow Mylinh Smith Don Elmajian Murali Ankem James A Cardelli

Functional food components ndash Polyphenols

ldquoNano-sized self assembled structured liquids = nanodrops Liquid carriers that pass through the digestive system effectively without sinking or breaking up to the absorption site These nanodrops carry the phytosterols to the large micelles that the body produces from the bile acid where they compete with cholesterol for entry into the micelle The phytosterols enter the micelle thereby inhibiting transportation of cholesterol from the digestive system into the bloodstreamrdquo Shemen Industries

Functional food components ndash Phytosterols

Goacutemez-Guilleacuten M C B Gimeacutenez et al (2011) Functional and bioactive properties of collagen and gelatin from alternative sources A review Food Hydrocolloids 25(8) 1813-1827

Functional food components ndash Bioactive peptides

httpwwwnuritascomscreening-mining-food-for-bioactive-peptides

Health and nutrition benefits associated with Fibregum its fermentation in the large bowel increases levels of beneficial bacteria which stimulates the production of short-chain fatty acids (SCFAs) that have such properties as lowering serum cholesterol it is a strong prebiotic helping to balance the intestinal microbial ecosystem in the distal colon

Functional food components ndash Prebiotic fiber

httpwwwnexiracomFibregumE284A2-healthy-prebiotic-fiber_6html

Senegalia senegal (acacia)

Functional food components ndash Essential minerals (Fe Zn Ca Se)

httpwwwfdagovFoodGuidanceRegulationGuidanceDocumentsRegulatoryInformationLabelingNutritionucm152626htm

Pseudocereals are considered an important energy source due to their starch content they also provide good quality protein dietary fibre and lipids rich in unsaturated fats They contain adequate levels of minerals and vitamins and significant amounts of other bioactive components such as saponins phytosterols squalene fagopyritols and polyphenols

Functional food components ndash micronutrients

httpquinuapewp-contentuploads201302antiox-Gallagherpdf

Seven-step process would ensure that functional foods are safe and effective with health claims that are accurate and regulatory oversight that is science based and efficient

Functional foods

FERGUS CLYDESDALE 2004 Functional Foods Opportunities amp Challenges Food Technology December 2004 Volume 58 No12

httpwwwgooglecompatentsUS20100196569

httpwwwgooglecompatentsWO2006048158A1cl=en

httpswwwgooglecompatentsUS6428824pg=PA2ampdq=Lepidium+peruvianumamphl=enampsa=Xampei=KxK2UanpKvOu4AOehICgDwampved=0CDoQ6AEwATgK

httpswwwgooglecompatentsUS7005148pg=PA3ampdq=vaccinium+corymbosumamphl=enampsa=Xampei=-xK2UZ7vF_a64AO0soG4Cgampsqi=2amppjf=1ampved=0CGwQ6AEwCA

httpswwwgooglecompatentsWO2001045648A2cl=enampdq=vaccinium+corymbosumamphl=enampsa=Xampei=9BO2Uc_5A9Sz4AOrsIEIampved=0CDQQ6AEwAA

Potential for future researchhellip

Top health issues consumers are concerned about preventing From NMI(2005)

A ELIZABETH SLOAN 2006 Top 10 Functional Food Trends Food Technology Volume 60 No 4

Microorganisms ndash fermented products

Fermented milks

Microorganisms ndash fermented products

Fermented milks

ldquoKefir grains are a combination of bacteria and yeasts in a matrix of proteins lipids and sugars and this symbiotic matrix forms grains that resemble cauliflower For this reason a complex and highly variable community of lactic acid bacteria and yeasts can be found in these grainsrdquo wwwwikipediaorg

Genus Lactobacillus Leuconostoc Pediococcus Streptococcus Bifidobacerium

Microorganisms ndash fermented products Fermented meats

Hutkins Robert W Microbiology and Technology of Fermented Foods

Pediococcus pentosaceus

httpbiowebusueduemlabcurrent20newshtml

Microorganisms ndash fermented products

Meat cultures

Lactobacillus sakei 10000-times magnified (Bild Joumlrg Groth Blessing Biotech GmbH)

Lactobacillus curvatus Lactobacillus plantarum Lactobacillus pentosus Streptococcus carnosus Micrococcus varians

httpwwwwzwtumdeindexphpid=185ampL=1amptx_ttnews5Btt_news5D=280

Microorganisms ndash fermented products

Meat cultures

httpwwwchr-hansencomproductsproduct-areasmeat-cultureshtml

Microorganisms ndash fermented products

Salami

ldquoPenicillium nalgiovense P chrysogenum and P camenberti used as starters The mold is desired as it imparts flavor helps the drying process prevents spoilage (mainly preventing growth of other mycotoxin-producing moulds during the curing process) and give a typical white color on the surfacerdquo

Microorganisms ndash fermented products

Wine amp Beer

Microorganisms ndash fermented products

Wine amp Beer

ldquoDuring fermentation the yeast converts the sugar in the wort to alcohol and carbon dioxide in addition to small amounts of glycerol and acetic acidrdquo

Yeast of the species Saccharomyces cerevisiae

httpenwikipediaorgwikiYeast

Microorganisms ndash other fermented products

httpwwwpsmicrographscoukrhizopus-mould--rhizopus-oligosporus-science-image80012871

Tempeh

Tempeh is manufactured from soaked boiled and dired soybeans that are inoculated with mold spores of species of Rhizopus (R stolonifer R oryzae R oigosporus or R arrhizus) The mash is packed or rolled in banana leaves and then incubated until there is good growth of mycelium but little sporulation Machve KK Fermentation Technology 2009

Functional food components

Critical Reviews in Food Science and Nutrition Structural Design Principles for Delivery of Bioactive Components in Nutraceuticals and Functional Foods 2011 McClements J Andrew E Yeonhwa D amp Weiss J

BioBest Omega 3 probiotic yogurt is a source of omega-3 PUFA that are considered an important part of a healthy diet It also contains over 1 billion active probiotic cultures Lactobacillus acidophilus NCFM Bifidobacterium lactis Bi-07 per serving that contribute to healthy digestive tract flora httpwwwastrocaproductsbiobest_omega_3_12x100g_multipackUbJJb_nVA8s

Functional food components ndash Omega 3

Inhibition of β-carotene degradation in oil-in-water nanoemulsions Influence of oil-soluble and water-soluble antioxidants Cheng Qian Eric Andrew Decker Hang Xiao David Julian McClements Volume 135 Issue 3 1 December 2012 Pages 1036ndash1043

Functional food components ndash Carotenoids

β-carotene enriched oil-in-water nanoemulsions stabilized by different emulsifiers with either no antioxidants (control) or antioxidants (80 μM EDTA + 10000 ppm vitamin E acetate)

Functional food components ndash Polyphenols

Pomegranate Phenolics from the Peels Arils and Flowers Are Antiatherogenic Studies in Vivo in Atherosclerotic Apolipoprotein E-Deficient (E0) Mice and in Vitro in Cultured Macrophages and Lipoproteins J Agric Food Chem 2008 56 (3) pp 1148ndash1157

Pomegranate phenolics and mainly oligomers punicalagin punicalin and gallic and ellagic acids are major contributors to the beneficial effects of pomegranate juice

Functional food components ndash Antioxidant activity

J Med Food 2012 Nov15(11)968-73 doi 101089jmf20122282 Epub 2012 Oct 12 Prickly pear cactus (Opuntia ficus indica var saboten) protects against stress-induced acute gastric lesions in rats (maltodextrin y betanin)

httpcancerpreventionresearchaacrjournalsorgcontentearly200906191940-6207CAPR-08-0167abstract

Tea Polyphenols Decrease Serum Levels of Prostate-Specific Antigen Hepatocyte Growth Factor and Vascular Endothelial Growth Factor in Prostate Cancer Patients and Inhibit Production of Hepatocyte Growth Factor and Vascular Endothelial Growth Factor In vitro 2008 Jerry McLarty Rebecca LH Bigelow Mylinh Smith Don Elmajian Murali Ankem James A Cardelli

Functional food components ndash Polyphenols

ldquoNano-sized self assembled structured liquids = nanodrops Liquid carriers that pass through the digestive system effectively without sinking or breaking up to the absorption site These nanodrops carry the phytosterols to the large micelles that the body produces from the bile acid where they compete with cholesterol for entry into the micelle The phytosterols enter the micelle thereby inhibiting transportation of cholesterol from the digestive system into the bloodstreamrdquo Shemen Industries

Functional food components ndash Phytosterols

Goacutemez-Guilleacuten M C B Gimeacutenez et al (2011) Functional and bioactive properties of collagen and gelatin from alternative sources A review Food Hydrocolloids 25(8) 1813-1827

Functional food components ndash Bioactive peptides

httpwwwnuritascomscreening-mining-food-for-bioactive-peptides

Health and nutrition benefits associated with Fibregum its fermentation in the large bowel increases levels of beneficial bacteria which stimulates the production of short-chain fatty acids (SCFAs) that have such properties as lowering serum cholesterol it is a strong prebiotic helping to balance the intestinal microbial ecosystem in the distal colon

Functional food components ndash Prebiotic fiber

httpwwwnexiracomFibregumE284A2-healthy-prebiotic-fiber_6html

Senegalia senegal (acacia)

Functional food components ndash Essential minerals (Fe Zn Ca Se)

httpwwwfdagovFoodGuidanceRegulationGuidanceDocumentsRegulatoryInformationLabelingNutritionucm152626htm

Pseudocereals are considered an important energy source due to their starch content they also provide good quality protein dietary fibre and lipids rich in unsaturated fats They contain adequate levels of minerals and vitamins and significant amounts of other bioactive components such as saponins phytosterols squalene fagopyritols and polyphenols

Functional food components ndash micronutrients

httpquinuapewp-contentuploads201302antiox-Gallagherpdf

Seven-step process would ensure that functional foods are safe and effective with health claims that are accurate and regulatory oversight that is science based and efficient

Functional foods

FERGUS CLYDESDALE 2004 Functional Foods Opportunities amp Challenges Food Technology December 2004 Volume 58 No12

httpwwwgooglecompatentsUS20100196569

httpwwwgooglecompatentsWO2006048158A1cl=en

httpswwwgooglecompatentsUS6428824pg=PA2ampdq=Lepidium+peruvianumamphl=enampsa=Xampei=KxK2UanpKvOu4AOehICgDwampved=0CDoQ6AEwATgK

httpswwwgooglecompatentsUS7005148pg=PA3ampdq=vaccinium+corymbosumamphl=enampsa=Xampei=-xK2UZ7vF_a64AO0soG4Cgampsqi=2amppjf=1ampved=0CGwQ6AEwCA

httpswwwgooglecompatentsWO2001045648A2cl=enampdq=vaccinium+corymbosumamphl=enampsa=Xampei=9BO2Uc_5A9Sz4AOrsIEIampved=0CDQQ6AEwAA

Potential for future researchhellip

Top health issues consumers are concerned about preventing From NMI(2005)

A ELIZABETH SLOAN 2006 Top 10 Functional Food Trends Food Technology Volume 60 No 4

Microorganisms ndash fermented products

Fermented milks

ldquoKefir grains are a combination of bacteria and yeasts in a matrix of proteins lipids and sugars and this symbiotic matrix forms grains that resemble cauliflower For this reason a complex and highly variable community of lactic acid bacteria and yeasts can be found in these grainsrdquo wwwwikipediaorg

Genus Lactobacillus Leuconostoc Pediococcus Streptococcus Bifidobacerium

Microorganisms ndash fermented products Fermented meats

Hutkins Robert W Microbiology and Technology of Fermented Foods

Pediococcus pentosaceus

httpbiowebusueduemlabcurrent20newshtml

Microorganisms ndash fermented products

Meat cultures

Lactobacillus sakei 10000-times magnified (Bild Joumlrg Groth Blessing Biotech GmbH)

Lactobacillus curvatus Lactobacillus plantarum Lactobacillus pentosus Streptococcus carnosus Micrococcus varians

httpwwwwzwtumdeindexphpid=185ampL=1amptx_ttnews5Btt_news5D=280

Microorganisms ndash fermented products

Meat cultures

httpwwwchr-hansencomproductsproduct-areasmeat-cultureshtml

Microorganisms ndash fermented products

Salami

ldquoPenicillium nalgiovense P chrysogenum and P camenberti used as starters The mold is desired as it imparts flavor helps the drying process prevents spoilage (mainly preventing growth of other mycotoxin-producing moulds during the curing process) and give a typical white color on the surfacerdquo

Microorganisms ndash fermented products

Wine amp Beer

Microorganisms ndash fermented products

Wine amp Beer

ldquoDuring fermentation the yeast converts the sugar in the wort to alcohol and carbon dioxide in addition to small amounts of glycerol and acetic acidrdquo

Yeast of the species Saccharomyces cerevisiae

httpenwikipediaorgwikiYeast

Microorganisms ndash other fermented products

httpwwwpsmicrographscoukrhizopus-mould--rhizopus-oligosporus-science-image80012871

Tempeh

Tempeh is manufactured from soaked boiled and dired soybeans that are inoculated with mold spores of species of Rhizopus (R stolonifer R oryzae R oigosporus or R arrhizus) The mash is packed or rolled in banana leaves and then incubated until there is good growth of mycelium but little sporulation Machve KK Fermentation Technology 2009

Functional food components

Critical Reviews in Food Science and Nutrition Structural Design Principles for Delivery of Bioactive Components in Nutraceuticals and Functional Foods 2011 McClements J Andrew E Yeonhwa D amp Weiss J

BioBest Omega 3 probiotic yogurt is a source of omega-3 PUFA that are considered an important part of a healthy diet It also contains over 1 billion active probiotic cultures Lactobacillus acidophilus NCFM Bifidobacterium lactis Bi-07 per serving that contribute to healthy digestive tract flora httpwwwastrocaproductsbiobest_omega_3_12x100g_multipackUbJJb_nVA8s

Functional food components ndash Omega 3

Inhibition of β-carotene degradation in oil-in-water nanoemulsions Influence of oil-soluble and water-soluble antioxidants Cheng Qian Eric Andrew Decker Hang Xiao David Julian McClements Volume 135 Issue 3 1 December 2012 Pages 1036ndash1043

Functional food components ndash Carotenoids

β-carotene enriched oil-in-water nanoemulsions stabilized by different emulsifiers with either no antioxidants (control) or antioxidants (80 μM EDTA + 10000 ppm vitamin E acetate)

Functional food components ndash Polyphenols

Pomegranate Phenolics from the Peels Arils and Flowers Are Antiatherogenic Studies in Vivo in Atherosclerotic Apolipoprotein E-Deficient (E0) Mice and in Vitro in Cultured Macrophages and Lipoproteins J Agric Food Chem 2008 56 (3) pp 1148ndash1157

Pomegranate phenolics and mainly oligomers punicalagin punicalin and gallic and ellagic acids are major contributors to the beneficial effects of pomegranate juice

Functional food components ndash Antioxidant activity

J Med Food 2012 Nov15(11)968-73 doi 101089jmf20122282 Epub 2012 Oct 12 Prickly pear cactus (Opuntia ficus indica var saboten) protects against stress-induced acute gastric lesions in rats (maltodextrin y betanin)

httpcancerpreventionresearchaacrjournalsorgcontentearly200906191940-6207CAPR-08-0167abstract

Tea Polyphenols Decrease Serum Levels of Prostate-Specific Antigen Hepatocyte Growth Factor and Vascular Endothelial Growth Factor in Prostate Cancer Patients and Inhibit Production of Hepatocyte Growth Factor and Vascular Endothelial Growth Factor In vitro 2008 Jerry McLarty Rebecca LH Bigelow Mylinh Smith Don Elmajian Murali Ankem James A Cardelli

Functional food components ndash Polyphenols

ldquoNano-sized self assembled structured liquids = nanodrops Liquid carriers that pass through the digestive system effectively without sinking or breaking up to the absorption site These nanodrops carry the phytosterols to the large micelles that the body produces from the bile acid where they compete with cholesterol for entry into the micelle The phytosterols enter the micelle thereby inhibiting transportation of cholesterol from the digestive system into the bloodstreamrdquo Shemen Industries

Functional food components ndash Phytosterols

Goacutemez-Guilleacuten M C B Gimeacutenez et al (2011) Functional and bioactive properties of collagen and gelatin from alternative sources A review Food Hydrocolloids 25(8) 1813-1827

Functional food components ndash Bioactive peptides

httpwwwnuritascomscreening-mining-food-for-bioactive-peptides

Health and nutrition benefits associated with Fibregum its fermentation in the large bowel increases levels of beneficial bacteria which stimulates the production of short-chain fatty acids (SCFAs) that have such properties as lowering serum cholesterol it is a strong prebiotic helping to balance the intestinal microbial ecosystem in the distal colon

Functional food components ndash Prebiotic fiber

httpwwwnexiracomFibregumE284A2-healthy-prebiotic-fiber_6html

Senegalia senegal (acacia)

Functional food components ndash Essential minerals (Fe Zn Ca Se)

httpwwwfdagovFoodGuidanceRegulationGuidanceDocumentsRegulatoryInformationLabelingNutritionucm152626htm

Pseudocereals are considered an important energy source due to their starch content they also provide good quality protein dietary fibre and lipids rich in unsaturated fats They contain adequate levels of minerals and vitamins and significant amounts of other bioactive components such as saponins phytosterols squalene fagopyritols and polyphenols

Functional food components ndash micronutrients

httpquinuapewp-contentuploads201302antiox-Gallagherpdf

Seven-step process would ensure that functional foods are safe and effective with health claims that are accurate and regulatory oversight that is science based and efficient

Functional foods

FERGUS CLYDESDALE 2004 Functional Foods Opportunities amp Challenges Food Technology December 2004 Volume 58 No12

httpwwwgooglecompatentsUS20100196569

httpwwwgooglecompatentsWO2006048158A1cl=en

httpswwwgooglecompatentsUS6428824pg=PA2ampdq=Lepidium+peruvianumamphl=enampsa=Xampei=KxK2UanpKvOu4AOehICgDwampved=0CDoQ6AEwATgK

httpswwwgooglecompatentsUS7005148pg=PA3ampdq=vaccinium+corymbosumamphl=enampsa=Xampei=-xK2UZ7vF_a64AO0soG4Cgampsqi=2amppjf=1ampved=0CGwQ6AEwCA

httpswwwgooglecompatentsWO2001045648A2cl=enampdq=vaccinium+corymbosumamphl=enampsa=Xampei=9BO2Uc_5A9Sz4AOrsIEIampved=0CDQQ6AEwAA

Potential for future researchhellip

Top health issues consumers are concerned about preventing From NMI(2005)

A ELIZABETH SLOAN 2006 Top 10 Functional Food Trends Food Technology Volume 60 No 4

Microorganisms ndash fermented products Fermented meats

Hutkins Robert W Microbiology and Technology of Fermented Foods

Pediococcus pentosaceus

httpbiowebusueduemlabcurrent20newshtml

Microorganisms ndash fermented products

Meat cultures

Lactobacillus sakei 10000-times magnified (Bild Joumlrg Groth Blessing Biotech GmbH)

Lactobacillus curvatus Lactobacillus plantarum Lactobacillus pentosus Streptococcus carnosus Micrococcus varians

httpwwwwzwtumdeindexphpid=185ampL=1amptx_ttnews5Btt_news5D=280

Microorganisms ndash fermented products

Meat cultures

httpwwwchr-hansencomproductsproduct-areasmeat-cultureshtml

Microorganisms ndash fermented products

Salami

ldquoPenicillium nalgiovense P chrysogenum and P camenberti used as starters The mold is desired as it imparts flavor helps the drying process prevents spoilage (mainly preventing growth of other mycotoxin-producing moulds during the curing process) and give a typical white color on the surfacerdquo

Microorganisms ndash fermented products

Wine amp Beer

Microorganisms ndash fermented products

Wine amp Beer

ldquoDuring fermentation the yeast converts the sugar in the wort to alcohol and carbon dioxide in addition to small amounts of glycerol and acetic acidrdquo

Yeast of the species Saccharomyces cerevisiae

httpenwikipediaorgwikiYeast

Microorganisms ndash other fermented products

httpwwwpsmicrographscoukrhizopus-mould--rhizopus-oligosporus-science-image80012871

Tempeh

Tempeh is manufactured from soaked boiled and dired soybeans that are inoculated with mold spores of species of Rhizopus (R stolonifer R oryzae R oigosporus or R arrhizus) The mash is packed or rolled in banana leaves and then incubated until there is good growth of mycelium but little sporulation Machve KK Fermentation Technology 2009

Functional food components

Critical Reviews in Food Science and Nutrition Structural Design Principles for Delivery of Bioactive Components in Nutraceuticals and Functional Foods 2011 McClements J Andrew E Yeonhwa D amp Weiss J

BioBest Omega 3 probiotic yogurt is a source of omega-3 PUFA that are considered an important part of a healthy diet It also contains over 1 billion active probiotic cultures Lactobacillus acidophilus NCFM Bifidobacterium lactis Bi-07 per serving that contribute to healthy digestive tract flora httpwwwastrocaproductsbiobest_omega_3_12x100g_multipackUbJJb_nVA8s

Functional food components ndash Omega 3

Inhibition of β-carotene degradation in oil-in-water nanoemulsions Influence of oil-soluble and water-soluble antioxidants Cheng Qian Eric Andrew Decker Hang Xiao David Julian McClements Volume 135 Issue 3 1 December 2012 Pages 1036ndash1043

Functional food components ndash Carotenoids

β-carotene enriched oil-in-water nanoemulsions stabilized by different emulsifiers with either no antioxidants (control) or antioxidants (80 μM EDTA + 10000 ppm vitamin E acetate)

Functional food components ndash Polyphenols

Pomegranate Phenolics from the Peels Arils and Flowers Are Antiatherogenic Studies in Vivo in Atherosclerotic Apolipoprotein E-Deficient (E0) Mice and in Vitro in Cultured Macrophages and Lipoproteins J Agric Food Chem 2008 56 (3) pp 1148ndash1157

Pomegranate phenolics and mainly oligomers punicalagin punicalin and gallic and ellagic acids are major contributors to the beneficial effects of pomegranate juice

Functional food components ndash Antioxidant activity

J Med Food 2012 Nov15(11)968-73 doi 101089jmf20122282 Epub 2012 Oct 12 Prickly pear cactus (Opuntia ficus indica var saboten) protects against stress-induced acute gastric lesions in rats (maltodextrin y betanin)

httpcancerpreventionresearchaacrjournalsorgcontentearly200906191940-6207CAPR-08-0167abstract

Tea Polyphenols Decrease Serum Levels of Prostate-Specific Antigen Hepatocyte Growth Factor and Vascular Endothelial Growth Factor in Prostate Cancer Patients and Inhibit Production of Hepatocyte Growth Factor and Vascular Endothelial Growth Factor In vitro 2008 Jerry McLarty Rebecca LH Bigelow Mylinh Smith Don Elmajian Murali Ankem James A Cardelli

Functional food components ndash Polyphenols

ldquoNano-sized self assembled structured liquids = nanodrops Liquid carriers that pass through the digestive system effectively without sinking or breaking up to the absorption site These nanodrops carry the phytosterols to the large micelles that the body produces from the bile acid where they compete with cholesterol for entry into the micelle The phytosterols enter the micelle thereby inhibiting transportation of cholesterol from the digestive system into the bloodstreamrdquo Shemen Industries

Functional food components ndash Phytosterols

Goacutemez-Guilleacuten M C B Gimeacutenez et al (2011) Functional and bioactive properties of collagen and gelatin from alternative sources A review Food Hydrocolloids 25(8) 1813-1827

Functional food components ndash Bioactive peptides

httpwwwnuritascomscreening-mining-food-for-bioactive-peptides

Health and nutrition benefits associated with Fibregum its fermentation in the large bowel increases levels of beneficial bacteria which stimulates the production of short-chain fatty acids (SCFAs) that have such properties as lowering serum cholesterol it is a strong prebiotic helping to balance the intestinal microbial ecosystem in the distal colon

Functional food components ndash Prebiotic fiber

httpwwwnexiracomFibregumE284A2-healthy-prebiotic-fiber_6html

Senegalia senegal (acacia)

Functional food components ndash Essential minerals (Fe Zn Ca Se)

httpwwwfdagovFoodGuidanceRegulationGuidanceDocumentsRegulatoryInformationLabelingNutritionucm152626htm

Pseudocereals are considered an important energy source due to their starch content they also provide good quality protein dietary fibre and lipids rich in unsaturated fats They contain adequate levels of minerals and vitamins and significant amounts of other bioactive components such as saponins phytosterols squalene fagopyritols and polyphenols

Functional food components ndash micronutrients

httpquinuapewp-contentuploads201302antiox-Gallagherpdf

Seven-step process would ensure that functional foods are safe and effective with health claims that are accurate and regulatory oversight that is science based and efficient

Functional foods

FERGUS CLYDESDALE 2004 Functional Foods Opportunities amp Challenges Food Technology December 2004 Volume 58 No12

httpwwwgooglecompatentsUS20100196569

httpwwwgooglecompatentsWO2006048158A1cl=en

httpswwwgooglecompatentsUS6428824pg=PA2ampdq=Lepidium+peruvianumamphl=enampsa=Xampei=KxK2UanpKvOu4AOehICgDwampved=0CDoQ6AEwATgK

httpswwwgooglecompatentsUS7005148pg=PA3ampdq=vaccinium+corymbosumamphl=enampsa=Xampei=-xK2UZ7vF_a64AO0soG4Cgampsqi=2amppjf=1ampved=0CGwQ6AEwCA

httpswwwgooglecompatentsWO2001045648A2cl=enampdq=vaccinium+corymbosumamphl=enampsa=Xampei=9BO2Uc_5A9Sz4AOrsIEIampved=0CDQQ6AEwAA

Potential for future researchhellip

Top health issues consumers are concerned about preventing From NMI(2005)

A ELIZABETH SLOAN 2006 Top 10 Functional Food Trends Food Technology Volume 60 No 4

Pediococcus pentosaceus

httpbiowebusueduemlabcurrent20newshtml

Microorganisms ndash fermented products

Meat cultures

Lactobacillus sakei 10000-times magnified (Bild Joumlrg Groth Blessing Biotech GmbH)

Lactobacillus curvatus Lactobacillus plantarum Lactobacillus pentosus Streptococcus carnosus Micrococcus varians

httpwwwwzwtumdeindexphpid=185ampL=1amptx_ttnews5Btt_news5D=280

Microorganisms ndash fermented products

Meat cultures

httpwwwchr-hansencomproductsproduct-areasmeat-cultureshtml

Microorganisms ndash fermented products

Salami

ldquoPenicillium nalgiovense P chrysogenum and P camenberti used as starters The mold is desired as it imparts flavor helps the drying process prevents spoilage (mainly preventing growth of other mycotoxin-producing moulds during the curing process) and give a typical white color on the surfacerdquo

Microorganisms ndash fermented products

Wine amp Beer

Microorganisms ndash fermented products

Wine amp Beer

ldquoDuring fermentation the yeast converts the sugar in the wort to alcohol and carbon dioxide in addition to small amounts of glycerol and acetic acidrdquo

Yeast of the species Saccharomyces cerevisiae

httpenwikipediaorgwikiYeast

Microorganisms ndash other fermented products

httpwwwpsmicrographscoukrhizopus-mould--rhizopus-oligosporus-science-image80012871

Tempeh

Tempeh is manufactured from soaked boiled and dired soybeans that are inoculated with mold spores of species of Rhizopus (R stolonifer R oryzae R oigosporus or R arrhizus) The mash is packed or rolled in banana leaves and then incubated until there is good growth of mycelium but little sporulation Machve KK Fermentation Technology 2009

Functional food components

Critical Reviews in Food Science and Nutrition Structural Design Principles for Delivery of Bioactive Components in Nutraceuticals and Functional Foods 2011 McClements J Andrew E Yeonhwa D amp Weiss J

BioBest Omega 3 probiotic yogurt is a source of omega-3 PUFA that are considered an important part of a healthy diet It also contains over 1 billion active probiotic cultures Lactobacillus acidophilus NCFM Bifidobacterium lactis Bi-07 per serving that contribute to healthy digestive tract flora httpwwwastrocaproductsbiobest_omega_3_12x100g_multipackUbJJb_nVA8s

Functional food components ndash Omega 3

Inhibition of β-carotene degradation in oil-in-water nanoemulsions Influence of oil-soluble and water-soluble antioxidants Cheng Qian Eric Andrew Decker Hang Xiao David Julian McClements Volume 135 Issue 3 1 December 2012 Pages 1036ndash1043

Functional food components ndash Carotenoids

β-carotene enriched oil-in-water nanoemulsions stabilized by different emulsifiers with either no antioxidants (control) or antioxidants (80 μM EDTA + 10000 ppm vitamin E acetate)

Functional food components ndash Polyphenols

Pomegranate Phenolics from the Peels Arils and Flowers Are Antiatherogenic Studies in Vivo in Atherosclerotic Apolipoprotein E-Deficient (E0) Mice and in Vitro in Cultured Macrophages and Lipoproteins J Agric Food Chem 2008 56 (3) pp 1148ndash1157

Pomegranate phenolics and mainly oligomers punicalagin punicalin and gallic and ellagic acids are major contributors to the beneficial effects of pomegranate juice

Functional food components ndash Antioxidant activity

J Med Food 2012 Nov15(11)968-73 doi 101089jmf20122282 Epub 2012 Oct 12 Prickly pear cactus (Opuntia ficus indica var saboten) protects against stress-induced acute gastric lesions in rats (maltodextrin y betanin)

httpcancerpreventionresearchaacrjournalsorgcontentearly200906191940-6207CAPR-08-0167abstract

Tea Polyphenols Decrease Serum Levels of Prostate-Specific Antigen Hepatocyte Growth Factor and Vascular Endothelial Growth Factor in Prostate Cancer Patients and Inhibit Production of Hepatocyte Growth Factor and Vascular Endothelial Growth Factor In vitro 2008 Jerry McLarty Rebecca LH Bigelow Mylinh Smith Don Elmajian Murali Ankem James A Cardelli

Functional food components ndash Polyphenols

ldquoNano-sized self assembled structured liquids = nanodrops Liquid carriers that pass through the digestive system effectively without sinking or breaking up to the absorption site These nanodrops carry the phytosterols to the large micelles that the body produces from the bile acid where they compete with cholesterol for entry into the micelle The phytosterols enter the micelle thereby inhibiting transportation of cholesterol from the digestive system into the bloodstreamrdquo Shemen Industries

Functional food components ndash Phytosterols

Goacutemez-Guilleacuten M C B Gimeacutenez et al (2011) Functional and bioactive properties of collagen and gelatin from alternative sources A review Food Hydrocolloids 25(8) 1813-1827

Functional food components ndash Bioactive peptides

httpwwwnuritascomscreening-mining-food-for-bioactive-peptides

Health and nutrition benefits associated with Fibregum its fermentation in the large bowel increases levels of beneficial bacteria which stimulates the production of short-chain fatty acids (SCFAs) that have such properties as lowering serum cholesterol it is a strong prebiotic helping to balance the intestinal microbial ecosystem in the distal colon

Functional food components ndash Prebiotic fiber

httpwwwnexiracomFibregumE284A2-healthy-prebiotic-fiber_6html

Senegalia senegal (acacia)

Functional food components ndash Essential minerals (Fe Zn Ca Se)

httpwwwfdagovFoodGuidanceRegulationGuidanceDocumentsRegulatoryInformationLabelingNutritionucm152626htm

Pseudocereals are considered an important energy source due to their starch content they also provide good quality protein dietary fibre and lipids rich in unsaturated fats They contain adequate levels of minerals and vitamins and significant amounts of other bioactive components such as saponins phytosterols squalene fagopyritols and polyphenols

Functional food components ndash micronutrients

httpquinuapewp-contentuploads201302antiox-Gallagherpdf

Seven-step process would ensure that functional foods are safe and effective with health claims that are accurate and regulatory oversight that is science based and efficient

Functional foods

FERGUS CLYDESDALE 2004 Functional Foods Opportunities amp Challenges Food Technology December 2004 Volume 58 No12

httpwwwgooglecompatentsUS20100196569

httpwwwgooglecompatentsWO2006048158A1cl=en

httpswwwgooglecompatentsUS6428824pg=PA2ampdq=Lepidium+peruvianumamphl=enampsa=Xampei=KxK2UanpKvOu4AOehICgDwampved=0CDoQ6AEwATgK

httpswwwgooglecompatentsUS7005148pg=PA3ampdq=vaccinium+corymbosumamphl=enampsa=Xampei=-xK2UZ7vF_a64AO0soG4Cgampsqi=2amppjf=1ampved=0CGwQ6AEwCA

httpswwwgooglecompatentsWO2001045648A2cl=enampdq=vaccinium+corymbosumamphl=enampsa=Xampei=9BO2Uc_5A9Sz4AOrsIEIampved=0CDQQ6AEwAA

Potential for future researchhellip

Top health issues consumers are concerned about preventing From NMI(2005)

A ELIZABETH SLOAN 2006 Top 10 Functional Food Trends Food Technology Volume 60 No 4

Microorganisms ndash fermented products

Meat cultures

httpwwwchr-hansencomproductsproduct-areasmeat-cultureshtml

Microorganisms ndash fermented products

Salami

ldquoPenicillium nalgiovense P chrysogenum and P camenberti used as starters The mold is desired as it imparts flavor helps the drying process prevents spoilage (mainly preventing growth of other mycotoxin-producing moulds during the curing process) and give a typical white color on the surfacerdquo

Microorganisms ndash fermented products

Wine amp Beer

Microorganisms ndash fermented products

Wine amp Beer

ldquoDuring fermentation the yeast converts the sugar in the wort to alcohol and carbon dioxide in addition to small amounts of glycerol and acetic acidrdquo

Yeast of the species Saccharomyces cerevisiae

httpenwikipediaorgwikiYeast

Microorganisms ndash other fermented products

httpwwwpsmicrographscoukrhizopus-mould--rhizopus-oligosporus-science-image80012871

Tempeh

Tempeh is manufactured from soaked boiled and dired soybeans that are inoculated with mold spores of species of Rhizopus (R stolonifer R oryzae R oigosporus or R arrhizus) The mash is packed or rolled in banana leaves and then incubated until there is good growth of mycelium but little sporulation Machve KK Fermentation Technology 2009

Functional food components

Critical Reviews in Food Science and Nutrition Structural Design Principles for Delivery of Bioactive Components in Nutraceuticals and Functional Foods 2011 McClements J Andrew E Yeonhwa D amp Weiss J

BioBest Omega 3 probiotic yogurt is a source of omega-3 PUFA that are considered an important part of a healthy diet It also contains over 1 billion active probiotic cultures Lactobacillus acidophilus NCFM Bifidobacterium lactis Bi-07 per serving that contribute to healthy digestive tract flora httpwwwastrocaproductsbiobest_omega_3_12x100g_multipackUbJJb_nVA8s

Functional food components ndash Omega 3

Inhibition of β-carotene degradation in oil-in-water nanoemulsions Influence of oil-soluble and water-soluble antioxidants Cheng Qian Eric Andrew Decker Hang Xiao David Julian McClements Volume 135 Issue 3 1 December 2012 Pages 1036ndash1043

Functional food components ndash Carotenoids

β-carotene enriched oil-in-water nanoemulsions stabilized by different emulsifiers with either no antioxidants (control) or antioxidants (80 μM EDTA + 10000 ppm vitamin E acetate)

Functional food components ndash Polyphenols

Pomegranate Phenolics from the Peels Arils and Flowers Are Antiatherogenic Studies in Vivo in Atherosclerotic Apolipoprotein E-Deficient (E0) Mice and in Vitro in Cultured Macrophages and Lipoproteins J Agric Food Chem 2008 56 (3) pp 1148ndash1157

Pomegranate phenolics and mainly oligomers punicalagin punicalin and gallic and ellagic acids are major contributors to the beneficial effects of pomegranate juice

Functional food components ndash Antioxidant activity

J Med Food 2012 Nov15(11)968-73 doi 101089jmf20122282 Epub 2012 Oct 12 Prickly pear cactus (Opuntia ficus indica var saboten) protects against stress-induced acute gastric lesions in rats (maltodextrin y betanin)

httpcancerpreventionresearchaacrjournalsorgcontentearly200906191940-6207CAPR-08-0167abstract

Tea Polyphenols Decrease Serum Levels of Prostate-Specific Antigen Hepatocyte Growth Factor and Vascular Endothelial Growth Factor in Prostate Cancer Patients and Inhibit Production of Hepatocyte Growth Factor and Vascular Endothelial Growth Factor In vitro 2008 Jerry McLarty Rebecca LH Bigelow Mylinh Smith Don Elmajian Murali Ankem James A Cardelli

Functional food components ndash Polyphenols

ldquoNano-sized self assembled structured liquids = nanodrops Liquid carriers that pass through the digestive system effectively without sinking or breaking up to the absorption site These nanodrops carry the phytosterols to the large micelles that the body produces from the bile acid where they compete with cholesterol for entry into the micelle The phytosterols enter the micelle thereby inhibiting transportation of cholesterol from the digestive system into the bloodstreamrdquo Shemen Industries

Functional food components ndash Phytosterols

Goacutemez-Guilleacuten M C B Gimeacutenez et al (2011) Functional and bioactive properties of collagen and gelatin from alternative sources A review Food Hydrocolloids 25(8) 1813-1827

Functional food components ndash Bioactive peptides

httpwwwnuritascomscreening-mining-food-for-bioactive-peptides

Health and nutrition benefits associated with Fibregum its fermentation in the large bowel increases levels of beneficial bacteria which stimulates the production of short-chain fatty acids (SCFAs) that have such properties as lowering serum cholesterol it is a strong prebiotic helping to balance the intestinal microbial ecosystem in the distal colon

Functional food components ndash Prebiotic fiber

httpwwwnexiracomFibregumE284A2-healthy-prebiotic-fiber_6html

Senegalia senegal (acacia)

Functional food components ndash Essential minerals (Fe Zn Ca Se)

httpwwwfdagovFoodGuidanceRegulationGuidanceDocumentsRegulatoryInformationLabelingNutritionucm152626htm

Pseudocereals are considered an important energy source due to their starch content they also provide good quality protein dietary fibre and lipids rich in unsaturated fats They contain adequate levels of minerals and vitamins and significant amounts of other bioactive components such as saponins phytosterols squalene fagopyritols and polyphenols

Functional food components ndash micronutrients

httpquinuapewp-contentuploads201302antiox-Gallagherpdf

Seven-step process would ensure that functional foods are safe and effective with health claims that are accurate and regulatory oversight that is science based and efficient

Functional foods

FERGUS CLYDESDALE 2004 Functional Foods Opportunities amp Challenges Food Technology December 2004 Volume 58 No12

httpwwwgooglecompatentsUS20100196569

httpwwwgooglecompatentsWO2006048158A1cl=en

httpswwwgooglecompatentsUS6428824pg=PA2ampdq=Lepidium+peruvianumamphl=enampsa=Xampei=KxK2UanpKvOu4AOehICgDwampved=0CDoQ6AEwATgK

httpswwwgooglecompatentsUS7005148pg=PA3ampdq=vaccinium+corymbosumamphl=enampsa=Xampei=-xK2UZ7vF_a64AO0soG4Cgampsqi=2amppjf=1ampved=0CGwQ6AEwCA

httpswwwgooglecompatentsWO2001045648A2cl=enampdq=vaccinium+corymbosumamphl=enampsa=Xampei=9BO2Uc_5A9Sz4AOrsIEIampved=0CDQQ6AEwAA

Potential for future researchhellip

Top health issues consumers are concerned about preventing From NMI(2005)

A ELIZABETH SLOAN 2006 Top 10 Functional Food Trends Food Technology Volume 60 No 4

Microorganisms ndash fermented products

Salami

ldquoPenicillium nalgiovense P chrysogenum and P camenberti used as starters The mold is desired as it imparts flavor helps the drying process prevents spoilage (mainly preventing growth of other mycotoxin-producing moulds during the curing process) and give a typical white color on the surfacerdquo

Microorganisms ndash fermented products

Wine amp Beer

Microorganisms ndash fermented products

Wine amp Beer

ldquoDuring fermentation the yeast converts the sugar in the wort to alcohol and carbon dioxide in addition to small amounts of glycerol and acetic acidrdquo

Yeast of the species Saccharomyces cerevisiae

httpenwikipediaorgwikiYeast

Microorganisms ndash other fermented products

httpwwwpsmicrographscoukrhizopus-mould--rhizopus-oligosporus-science-image80012871

Tempeh

Tempeh is manufactured from soaked boiled and dired soybeans that are inoculated with mold spores of species of Rhizopus (R stolonifer R oryzae R oigosporus or R arrhizus) The mash is packed or rolled in banana leaves and then incubated until there is good growth of mycelium but little sporulation Machve KK Fermentation Technology 2009

Functional food components

Critical Reviews in Food Science and Nutrition Structural Design Principles for Delivery of Bioactive Components in Nutraceuticals and Functional Foods 2011 McClements J Andrew E Yeonhwa D amp Weiss J

BioBest Omega 3 probiotic yogurt is a source of omega-3 PUFA that are considered an important part of a healthy diet It also contains over 1 billion active probiotic cultures Lactobacillus acidophilus NCFM Bifidobacterium lactis Bi-07 per serving that contribute to healthy digestive tract flora httpwwwastrocaproductsbiobest_omega_3_12x100g_multipackUbJJb_nVA8s

Functional food components ndash Omega 3

Inhibition of β-carotene degradation in oil-in-water nanoemulsions Influence of oil-soluble and water-soluble antioxidants Cheng Qian Eric Andrew Decker Hang Xiao David Julian McClements Volume 135 Issue 3 1 December 2012 Pages 1036ndash1043

Functional food components ndash Carotenoids

β-carotene enriched oil-in-water nanoemulsions stabilized by different emulsifiers with either no antioxidants (control) or antioxidants (80 μM EDTA + 10000 ppm vitamin E acetate)

Functional food components ndash Polyphenols

Pomegranate Phenolics from the Peels Arils and Flowers Are Antiatherogenic Studies in Vivo in Atherosclerotic Apolipoprotein E-Deficient (E0) Mice and in Vitro in Cultured Macrophages and Lipoproteins J Agric Food Chem 2008 56 (3) pp 1148ndash1157

Pomegranate phenolics and mainly oligomers punicalagin punicalin and gallic and ellagic acids are major contributors to the beneficial effects of pomegranate juice

Functional food components ndash Antioxidant activity

J Med Food 2012 Nov15(11)968-73 doi 101089jmf20122282 Epub 2012 Oct 12 Prickly pear cactus (Opuntia ficus indica var saboten) protects against stress-induced acute gastric lesions in rats (maltodextrin y betanin)

httpcancerpreventionresearchaacrjournalsorgcontentearly200906191940-6207CAPR-08-0167abstract

Tea Polyphenols Decrease Serum Levels of Prostate-Specific Antigen Hepatocyte Growth Factor and Vascular Endothelial Growth Factor in Prostate Cancer Patients and Inhibit Production of Hepatocyte Growth Factor and Vascular Endothelial Growth Factor In vitro 2008 Jerry McLarty Rebecca LH Bigelow Mylinh Smith Don Elmajian Murali Ankem James A Cardelli

Functional food components ndash Polyphenols

ldquoNano-sized self assembled structured liquids = nanodrops Liquid carriers that pass through the digestive system effectively without sinking or breaking up to the absorption site These nanodrops carry the phytosterols to the large micelles that the body produces from the bile acid where they compete with cholesterol for entry into the micelle The phytosterols enter the micelle thereby inhibiting transportation of cholesterol from the digestive system into the bloodstreamrdquo Shemen Industries

Functional food components ndash Phytosterols

Goacutemez-Guilleacuten M C B Gimeacutenez et al (2011) Functional and bioactive properties of collagen and gelatin from alternative sources A review Food Hydrocolloids 25(8) 1813-1827

Functional food components ndash Bioactive peptides

httpwwwnuritascomscreening-mining-food-for-bioactive-peptides

Health and nutrition benefits associated with Fibregum its fermentation in the large bowel increases levels of beneficial bacteria which stimulates the production of short-chain fatty acids (SCFAs) that have such properties as lowering serum cholesterol it is a strong prebiotic helping to balance the intestinal microbial ecosystem in the distal colon

Functional food components ndash Prebiotic fiber

httpwwwnexiracomFibregumE284A2-healthy-prebiotic-fiber_6html

Senegalia senegal (acacia)

Functional food components ndash Essential minerals (Fe Zn Ca Se)

httpwwwfdagovFoodGuidanceRegulationGuidanceDocumentsRegulatoryInformationLabelingNutritionucm152626htm

Pseudocereals are considered an important energy source due to their starch content they also provide good quality protein dietary fibre and lipids rich in unsaturated fats They contain adequate levels of minerals and vitamins and significant amounts of other bioactive components such as saponins phytosterols squalene fagopyritols and polyphenols

Functional food components ndash micronutrients

httpquinuapewp-contentuploads201302antiox-Gallagherpdf

Seven-step process would ensure that functional foods are safe and effective with health claims that are accurate and regulatory oversight that is science based and efficient

Functional foods

FERGUS CLYDESDALE 2004 Functional Foods Opportunities amp Challenges Food Technology December 2004 Volume 58 No12

httpwwwgooglecompatentsUS20100196569

httpwwwgooglecompatentsWO2006048158A1cl=en

httpswwwgooglecompatentsUS6428824pg=PA2ampdq=Lepidium+peruvianumamphl=enampsa=Xampei=KxK2UanpKvOu4AOehICgDwampved=0CDoQ6AEwATgK

httpswwwgooglecompatentsUS7005148pg=PA3ampdq=vaccinium+corymbosumamphl=enampsa=Xampei=-xK2UZ7vF_a64AO0soG4Cgampsqi=2amppjf=1ampved=0CGwQ6AEwCA

httpswwwgooglecompatentsWO2001045648A2cl=enampdq=vaccinium+corymbosumamphl=enampsa=Xampei=9BO2Uc_5A9Sz4AOrsIEIampved=0CDQQ6AEwAA

Potential for future researchhellip

Top health issues consumers are concerned about preventing From NMI(2005)

A ELIZABETH SLOAN 2006 Top 10 Functional Food Trends Food Technology Volume 60 No 4

Microorganisms ndash fermented products

Wine amp Beer

Microorganisms ndash fermented products

Wine amp Beer

ldquoDuring fermentation the yeast converts the sugar in the wort to alcohol and carbon dioxide in addition to small amounts of glycerol and acetic acidrdquo

Yeast of the species Saccharomyces cerevisiae

httpenwikipediaorgwikiYeast

Microorganisms ndash other fermented products

httpwwwpsmicrographscoukrhizopus-mould--rhizopus-oligosporus-science-image80012871

Tempeh

Tempeh is manufactured from soaked boiled and dired soybeans that are inoculated with mold spores of species of Rhizopus (R stolonifer R oryzae R oigosporus or R arrhizus) The mash is packed or rolled in banana leaves and then incubated until there is good growth of mycelium but little sporulation Machve KK Fermentation Technology 2009

Functional food components

Critical Reviews in Food Science and Nutrition Structural Design Principles for Delivery of Bioactive Components in Nutraceuticals and Functional Foods 2011 McClements J Andrew E Yeonhwa D amp Weiss J

BioBest Omega 3 probiotic yogurt is a source of omega-3 PUFA that are considered an important part of a healthy diet It also contains over 1 billion active probiotic cultures Lactobacillus acidophilus NCFM Bifidobacterium lactis Bi-07 per serving that contribute to healthy digestive tract flora httpwwwastrocaproductsbiobest_omega_3_12x100g_multipackUbJJb_nVA8s

Functional food components ndash Omega 3

Inhibition of β-carotene degradation in oil-in-water nanoemulsions Influence of oil-soluble and water-soluble antioxidants Cheng Qian Eric Andrew Decker Hang Xiao David Julian McClements Volume 135 Issue 3 1 December 2012 Pages 1036ndash1043

Functional food components ndash Carotenoids

β-carotene enriched oil-in-water nanoemulsions stabilized by different emulsifiers with either no antioxidants (control) or antioxidants (80 μM EDTA + 10000 ppm vitamin E acetate)

Functional food components ndash Polyphenols

Pomegranate Phenolics from the Peels Arils and Flowers Are Antiatherogenic Studies in Vivo in Atherosclerotic Apolipoprotein E-Deficient (E0) Mice and in Vitro in Cultured Macrophages and Lipoproteins J Agric Food Chem 2008 56 (3) pp 1148ndash1157

Pomegranate phenolics and mainly oligomers punicalagin punicalin and gallic and ellagic acids are major contributors to the beneficial effects of pomegranate juice

Functional food components ndash Antioxidant activity

J Med Food 2012 Nov15(11)968-73 doi 101089jmf20122282 Epub 2012 Oct 12 Prickly pear cactus (Opuntia ficus indica var saboten) protects against stress-induced acute gastric lesions in rats (maltodextrin y betanin)

httpcancerpreventionresearchaacrjournalsorgcontentearly200906191940-6207CAPR-08-0167abstract

Tea Polyphenols Decrease Serum Levels of Prostate-Specific Antigen Hepatocyte Growth Factor and Vascular Endothelial Growth Factor in Prostate Cancer Patients and Inhibit Production of Hepatocyte Growth Factor and Vascular Endothelial Growth Factor In vitro 2008 Jerry McLarty Rebecca LH Bigelow Mylinh Smith Don Elmajian Murali Ankem James A Cardelli

Functional food components ndash Polyphenols

ldquoNano-sized self assembled structured liquids = nanodrops Liquid carriers that pass through the digestive system effectively without sinking or breaking up to the absorption site These nanodrops carry the phytosterols to the large micelles that the body produces from the bile acid where they compete with cholesterol for entry into the micelle The phytosterols enter the micelle thereby inhibiting transportation of cholesterol from the digestive system into the bloodstreamrdquo Shemen Industries

Functional food components ndash Phytosterols

Goacutemez-Guilleacuten M C B Gimeacutenez et al (2011) Functional and bioactive properties of collagen and gelatin from alternative sources A review Food Hydrocolloids 25(8) 1813-1827

Functional food components ndash Bioactive peptides

httpwwwnuritascomscreening-mining-food-for-bioactive-peptides

Health and nutrition benefits associated with Fibregum its fermentation in the large bowel increases levels of beneficial bacteria which stimulates the production of short-chain fatty acids (SCFAs) that have such properties as lowering serum cholesterol it is a strong prebiotic helping to balance the intestinal microbial ecosystem in the distal colon

Functional food components ndash Prebiotic fiber

httpwwwnexiracomFibregumE284A2-healthy-prebiotic-fiber_6html

Senegalia senegal (acacia)

Functional food components ndash Essential minerals (Fe Zn Ca Se)

httpwwwfdagovFoodGuidanceRegulationGuidanceDocumentsRegulatoryInformationLabelingNutritionucm152626htm

Pseudocereals are considered an important energy source due to their starch content they also provide good quality protein dietary fibre and lipids rich in unsaturated fats They contain adequate levels of minerals and vitamins and significant amounts of other bioactive components such as saponins phytosterols squalene fagopyritols and polyphenols

Functional food components ndash micronutrients

httpquinuapewp-contentuploads201302antiox-Gallagherpdf

Seven-step process would ensure that functional foods are safe and effective with health claims that are accurate and regulatory oversight that is science based and efficient

Functional foods

FERGUS CLYDESDALE 2004 Functional Foods Opportunities amp Challenges Food Technology December 2004 Volume 58 No12

httpwwwgooglecompatentsUS20100196569

httpwwwgooglecompatentsWO2006048158A1cl=en

httpswwwgooglecompatentsUS6428824pg=PA2ampdq=Lepidium+peruvianumamphl=enampsa=Xampei=KxK2UanpKvOu4AOehICgDwampved=0CDoQ6AEwATgK

httpswwwgooglecompatentsUS7005148pg=PA3ampdq=vaccinium+corymbosumamphl=enampsa=Xampei=-xK2UZ7vF_a64AO0soG4Cgampsqi=2amppjf=1ampved=0CGwQ6AEwCA

httpswwwgooglecompatentsWO2001045648A2cl=enampdq=vaccinium+corymbosumamphl=enampsa=Xampei=9BO2Uc_5A9Sz4AOrsIEIampved=0CDQQ6AEwAA

Potential for future researchhellip

Top health issues consumers are concerned about preventing From NMI(2005)

A ELIZABETH SLOAN 2006 Top 10 Functional Food Trends Food Technology Volume 60 No 4

Microorganisms ndash fermented products

Wine amp Beer

ldquoDuring fermentation the yeast converts the sugar in the wort to alcohol and carbon dioxide in addition to small amounts of glycerol and acetic acidrdquo

Yeast of the species Saccharomyces cerevisiae

httpenwikipediaorgwikiYeast

Microorganisms ndash other fermented products

httpwwwpsmicrographscoukrhizopus-mould--rhizopus-oligosporus-science-image80012871

Tempeh

Tempeh is manufactured from soaked boiled and dired soybeans that are inoculated with mold spores of species of Rhizopus (R stolonifer R oryzae R oigosporus or R arrhizus) The mash is packed or rolled in banana leaves and then incubated until there is good growth of mycelium but little sporulation Machve KK Fermentation Technology 2009

Functional food components

Critical Reviews in Food Science and Nutrition Structural Design Principles for Delivery of Bioactive Components in Nutraceuticals and Functional Foods 2011 McClements J Andrew E Yeonhwa D amp Weiss J

BioBest Omega 3 probiotic yogurt is a source of omega-3 PUFA that are considered an important part of a healthy diet It also contains over 1 billion active probiotic cultures Lactobacillus acidophilus NCFM Bifidobacterium lactis Bi-07 per serving that contribute to healthy digestive tract flora httpwwwastrocaproductsbiobest_omega_3_12x100g_multipackUbJJb_nVA8s

Functional food components ndash Omega 3

Inhibition of β-carotene degradation in oil-in-water nanoemulsions Influence of oil-soluble and water-soluble antioxidants Cheng Qian Eric Andrew Decker Hang Xiao David Julian McClements Volume 135 Issue 3 1 December 2012 Pages 1036ndash1043

Functional food components ndash Carotenoids

β-carotene enriched oil-in-water nanoemulsions stabilized by different emulsifiers with either no antioxidants (control) or antioxidants (80 μM EDTA + 10000 ppm vitamin E acetate)

Functional food components ndash Polyphenols

Pomegranate Phenolics from the Peels Arils and Flowers Are Antiatherogenic Studies in Vivo in Atherosclerotic Apolipoprotein E-Deficient (E0) Mice and in Vitro in Cultured Macrophages and Lipoproteins J Agric Food Chem 2008 56 (3) pp 1148ndash1157

Pomegranate phenolics and mainly oligomers punicalagin punicalin and gallic and ellagic acids are major contributors to the beneficial effects of pomegranate juice

Functional food components ndash Antioxidant activity

J Med Food 2012 Nov15(11)968-73 doi 101089jmf20122282 Epub 2012 Oct 12 Prickly pear cactus (Opuntia ficus indica var saboten) protects against stress-induced acute gastric lesions in rats (maltodextrin y betanin)

httpcancerpreventionresearchaacrjournalsorgcontentearly200906191940-6207CAPR-08-0167abstract

Tea Polyphenols Decrease Serum Levels of Prostate-Specific Antigen Hepatocyte Growth Factor and Vascular Endothelial Growth Factor in Prostate Cancer Patients and Inhibit Production of Hepatocyte Growth Factor and Vascular Endothelial Growth Factor In vitro 2008 Jerry McLarty Rebecca LH Bigelow Mylinh Smith Don Elmajian Murali Ankem James A Cardelli

Functional food components ndash Polyphenols

ldquoNano-sized self assembled structured liquids = nanodrops Liquid carriers that pass through the digestive system effectively without sinking or breaking up to the absorption site These nanodrops carry the phytosterols to the large micelles that the body produces from the bile acid where they compete with cholesterol for entry into the micelle The phytosterols enter the micelle thereby inhibiting transportation of cholesterol from the digestive system into the bloodstreamrdquo Shemen Industries

Functional food components ndash Phytosterols

Goacutemez-Guilleacuten M C B Gimeacutenez et al (2011) Functional and bioactive properties of collagen and gelatin from alternative sources A review Food Hydrocolloids 25(8) 1813-1827

Functional food components ndash Bioactive peptides

httpwwwnuritascomscreening-mining-food-for-bioactive-peptides

Health and nutrition benefits associated with Fibregum its fermentation in the large bowel increases levels of beneficial bacteria which stimulates the production of short-chain fatty acids (SCFAs) that have such properties as lowering serum cholesterol it is a strong prebiotic helping to balance the intestinal microbial ecosystem in the distal colon

Functional food components ndash Prebiotic fiber

httpwwwnexiracomFibregumE284A2-healthy-prebiotic-fiber_6html

Senegalia senegal (acacia)

Functional food components ndash Essential minerals (Fe Zn Ca Se)

httpwwwfdagovFoodGuidanceRegulationGuidanceDocumentsRegulatoryInformationLabelingNutritionucm152626htm

Pseudocereals are considered an important energy source due to their starch content they also provide good quality protein dietary fibre and lipids rich in unsaturated fats They contain adequate levels of minerals and vitamins and significant amounts of other bioactive components such as saponins phytosterols squalene fagopyritols and polyphenols

Functional food components ndash micronutrients

httpquinuapewp-contentuploads201302antiox-Gallagherpdf

Seven-step process would ensure that functional foods are safe and effective with health claims that are accurate and regulatory oversight that is science based and efficient

Functional foods

FERGUS CLYDESDALE 2004 Functional Foods Opportunities amp Challenges Food Technology December 2004 Volume 58 No12

httpwwwgooglecompatentsUS20100196569

httpwwwgooglecompatentsWO2006048158A1cl=en

httpswwwgooglecompatentsUS6428824pg=PA2ampdq=Lepidium+peruvianumamphl=enampsa=Xampei=KxK2UanpKvOu4AOehICgDwampved=0CDoQ6AEwATgK

httpswwwgooglecompatentsUS7005148pg=PA3ampdq=vaccinium+corymbosumamphl=enampsa=Xampei=-xK2UZ7vF_a64AO0soG4Cgampsqi=2amppjf=1ampved=0CGwQ6AEwCA

httpswwwgooglecompatentsWO2001045648A2cl=enampdq=vaccinium+corymbosumamphl=enampsa=Xampei=9BO2Uc_5A9Sz4AOrsIEIampved=0CDQQ6AEwAA

Potential for future researchhellip

Top health issues consumers are concerned about preventing From NMI(2005)

A ELIZABETH SLOAN 2006 Top 10 Functional Food Trends Food Technology Volume 60 No 4

Microorganisms ndash other fermented products

httpwwwpsmicrographscoukrhizopus-mould--rhizopus-oligosporus-science-image80012871

Tempeh

Tempeh is manufactured from soaked boiled and dired soybeans that are inoculated with mold spores of species of Rhizopus (R stolonifer R oryzae R oigosporus or R arrhizus) The mash is packed or rolled in banana leaves and then incubated until there is good growth of mycelium but little sporulation Machve KK Fermentation Technology 2009

Functional food components

Critical Reviews in Food Science and Nutrition Structural Design Principles for Delivery of Bioactive Components in Nutraceuticals and Functional Foods 2011 McClements J Andrew E Yeonhwa D amp Weiss J

BioBest Omega 3 probiotic yogurt is a source of omega-3 PUFA that are considered an important part of a healthy diet It also contains over 1 billion active probiotic cultures Lactobacillus acidophilus NCFM Bifidobacterium lactis Bi-07 per serving that contribute to healthy digestive tract flora httpwwwastrocaproductsbiobest_omega_3_12x100g_multipackUbJJb_nVA8s

Functional food components ndash Omega 3

Inhibition of β-carotene degradation in oil-in-water nanoemulsions Influence of oil-soluble and water-soluble antioxidants Cheng Qian Eric Andrew Decker Hang Xiao David Julian McClements Volume 135 Issue 3 1 December 2012 Pages 1036ndash1043

Functional food components ndash Carotenoids

β-carotene enriched oil-in-water nanoemulsions stabilized by different emulsifiers with either no antioxidants (control) or antioxidants (80 μM EDTA + 10000 ppm vitamin E acetate)

Functional food components ndash Polyphenols

Pomegranate Phenolics from the Peels Arils and Flowers Are Antiatherogenic Studies in Vivo in Atherosclerotic Apolipoprotein E-Deficient (E0) Mice and in Vitro in Cultured Macrophages and Lipoproteins J Agric Food Chem 2008 56 (3) pp 1148ndash1157

Pomegranate phenolics and mainly oligomers punicalagin punicalin and gallic and ellagic acids are major contributors to the beneficial effects of pomegranate juice

Functional food components ndash Antioxidant activity

J Med Food 2012 Nov15(11)968-73 doi 101089jmf20122282 Epub 2012 Oct 12 Prickly pear cactus (Opuntia ficus indica var saboten) protects against stress-induced acute gastric lesions in rats (maltodextrin y betanin)

httpcancerpreventionresearchaacrjournalsorgcontentearly200906191940-6207CAPR-08-0167abstract

Tea Polyphenols Decrease Serum Levels of Prostate-Specific Antigen Hepatocyte Growth Factor and Vascular Endothelial Growth Factor in Prostate Cancer Patients and Inhibit Production of Hepatocyte Growth Factor and Vascular Endothelial Growth Factor In vitro 2008 Jerry McLarty Rebecca LH Bigelow Mylinh Smith Don Elmajian Murali Ankem James A Cardelli

Functional food components ndash Polyphenols

ldquoNano-sized self assembled structured liquids = nanodrops Liquid carriers that pass through the digestive system effectively without sinking or breaking up to the absorption site These nanodrops carry the phytosterols to the large micelles that the body produces from the bile acid where they compete with cholesterol for entry into the micelle The phytosterols enter the micelle thereby inhibiting transportation of cholesterol from the digestive system into the bloodstreamrdquo Shemen Industries

Functional food components ndash Phytosterols

Goacutemez-Guilleacuten M C B Gimeacutenez et al (2011) Functional and bioactive properties of collagen and gelatin from alternative sources A review Food Hydrocolloids 25(8) 1813-1827

Functional food components ndash Bioactive peptides

httpwwwnuritascomscreening-mining-food-for-bioactive-peptides

Health and nutrition benefits associated with Fibregum its fermentation in the large bowel increases levels of beneficial bacteria which stimulates the production of short-chain fatty acids (SCFAs) that have such properties as lowering serum cholesterol it is a strong prebiotic helping to balance the intestinal microbial ecosystem in the distal colon

Functional food components ndash Prebiotic fiber

httpwwwnexiracomFibregumE284A2-healthy-prebiotic-fiber_6html

Senegalia senegal (acacia)

Functional food components ndash Essential minerals (Fe Zn Ca Se)

httpwwwfdagovFoodGuidanceRegulationGuidanceDocumentsRegulatoryInformationLabelingNutritionucm152626htm

Pseudocereals are considered an important energy source due to their starch content they also provide good quality protein dietary fibre and lipids rich in unsaturated fats They contain adequate levels of minerals and vitamins and significant amounts of other bioactive components such as saponins phytosterols squalene fagopyritols and polyphenols

Functional food components ndash micronutrients

httpquinuapewp-contentuploads201302antiox-Gallagherpdf

Seven-step process would ensure that functional foods are safe and effective with health claims that are accurate and regulatory oversight that is science based and efficient

Functional foods

FERGUS CLYDESDALE 2004 Functional Foods Opportunities amp Challenges Food Technology December 2004 Volume 58 No12

httpwwwgooglecompatentsUS20100196569

httpwwwgooglecompatentsWO2006048158A1cl=en

httpswwwgooglecompatentsUS6428824pg=PA2ampdq=Lepidium+peruvianumamphl=enampsa=Xampei=KxK2UanpKvOu4AOehICgDwampved=0CDoQ6AEwATgK

httpswwwgooglecompatentsUS7005148pg=PA3ampdq=vaccinium+corymbosumamphl=enampsa=Xampei=-xK2UZ7vF_a64AO0soG4Cgampsqi=2amppjf=1ampved=0CGwQ6AEwCA

httpswwwgooglecompatentsWO2001045648A2cl=enampdq=vaccinium+corymbosumamphl=enampsa=Xampei=9BO2Uc_5A9Sz4AOrsIEIampved=0CDQQ6AEwAA

Potential for future researchhellip

Top health issues consumers are concerned about preventing From NMI(2005)

A ELIZABETH SLOAN 2006 Top 10 Functional Food Trends Food Technology Volume 60 No 4

Functional food components

Critical Reviews in Food Science and Nutrition Structural Design Principles for Delivery of Bioactive Components in Nutraceuticals and Functional Foods 2011 McClements J Andrew E Yeonhwa D amp Weiss J

BioBest Omega 3 probiotic yogurt is a source of omega-3 PUFA that are considered an important part of a healthy diet It also contains over 1 billion active probiotic cultures Lactobacillus acidophilus NCFM Bifidobacterium lactis Bi-07 per serving that contribute to healthy digestive tract flora httpwwwastrocaproductsbiobest_omega_3_12x100g_multipackUbJJb_nVA8s

Functional food components ndash Omega 3

Inhibition of β-carotene degradation in oil-in-water nanoemulsions Influence of oil-soluble and water-soluble antioxidants Cheng Qian Eric Andrew Decker Hang Xiao David Julian McClements Volume 135 Issue 3 1 December 2012 Pages 1036ndash1043

Functional food components ndash Carotenoids

β-carotene enriched oil-in-water nanoemulsions stabilized by different emulsifiers with either no antioxidants (control) or antioxidants (80 μM EDTA + 10000 ppm vitamin E acetate)

Functional food components ndash Polyphenols

Pomegranate Phenolics from the Peels Arils and Flowers Are Antiatherogenic Studies in Vivo in Atherosclerotic Apolipoprotein E-Deficient (E0) Mice and in Vitro in Cultured Macrophages and Lipoproteins J Agric Food Chem 2008 56 (3) pp 1148ndash1157

Pomegranate phenolics and mainly oligomers punicalagin punicalin and gallic and ellagic acids are major contributors to the beneficial effects of pomegranate juice

Functional food components ndash Antioxidant activity

J Med Food 2012 Nov15(11)968-73 doi 101089jmf20122282 Epub 2012 Oct 12 Prickly pear cactus (Opuntia ficus indica var saboten) protects against stress-induced acute gastric lesions in rats (maltodextrin y betanin)

httpcancerpreventionresearchaacrjournalsorgcontentearly200906191940-6207CAPR-08-0167abstract

Tea Polyphenols Decrease Serum Levels of Prostate-Specific Antigen Hepatocyte Growth Factor and Vascular Endothelial Growth Factor in Prostate Cancer Patients and Inhibit Production of Hepatocyte Growth Factor and Vascular Endothelial Growth Factor In vitro 2008 Jerry McLarty Rebecca LH Bigelow Mylinh Smith Don Elmajian Murali Ankem James A Cardelli

Functional food components ndash Polyphenols

ldquoNano-sized self assembled structured liquids = nanodrops Liquid carriers that pass through the digestive system effectively without sinking or breaking up to the absorption site These nanodrops carry the phytosterols to the large micelles that the body produces from the bile acid where they compete with cholesterol for entry into the micelle The phytosterols enter the micelle thereby inhibiting transportation of cholesterol from the digestive system into the bloodstreamrdquo Shemen Industries

Functional food components ndash Phytosterols

Goacutemez-Guilleacuten M C B Gimeacutenez et al (2011) Functional and bioactive properties of collagen and gelatin from alternative sources A review Food Hydrocolloids 25(8) 1813-1827

Functional food components ndash Bioactive peptides

httpwwwnuritascomscreening-mining-food-for-bioactive-peptides

Health and nutrition benefits associated with Fibregum its fermentation in the large bowel increases levels of beneficial bacteria which stimulates the production of short-chain fatty acids (SCFAs) that have such properties as lowering serum cholesterol it is a strong prebiotic helping to balance the intestinal microbial ecosystem in the distal colon

Functional food components ndash Prebiotic fiber

httpwwwnexiracomFibregumE284A2-healthy-prebiotic-fiber_6html

Senegalia senegal (acacia)

Functional food components ndash Essential minerals (Fe Zn Ca Se)

httpwwwfdagovFoodGuidanceRegulationGuidanceDocumentsRegulatoryInformationLabelingNutritionucm152626htm

Pseudocereals are considered an important energy source due to their starch content they also provide good quality protein dietary fibre and lipids rich in unsaturated fats They contain adequate levels of minerals and vitamins and significant amounts of other bioactive components such as saponins phytosterols squalene fagopyritols and polyphenols

Functional food components ndash micronutrients

httpquinuapewp-contentuploads201302antiox-Gallagherpdf

Seven-step process would ensure that functional foods are safe and effective with health claims that are accurate and regulatory oversight that is science based and efficient

Functional foods

FERGUS CLYDESDALE 2004 Functional Foods Opportunities amp Challenges Food Technology December 2004 Volume 58 No12

httpwwwgooglecompatentsUS20100196569

httpwwwgooglecompatentsWO2006048158A1cl=en

httpswwwgooglecompatentsUS6428824pg=PA2ampdq=Lepidium+peruvianumamphl=enampsa=Xampei=KxK2UanpKvOu4AOehICgDwampved=0CDoQ6AEwATgK

httpswwwgooglecompatentsUS7005148pg=PA3ampdq=vaccinium+corymbosumamphl=enampsa=Xampei=-xK2UZ7vF_a64AO0soG4Cgampsqi=2amppjf=1ampved=0CGwQ6AEwCA

httpswwwgooglecompatentsWO2001045648A2cl=enampdq=vaccinium+corymbosumamphl=enampsa=Xampei=9BO2Uc_5A9Sz4AOrsIEIampved=0CDQQ6AEwAA

Potential for future researchhellip

Top health issues consumers are concerned about preventing From NMI(2005)

A ELIZABETH SLOAN 2006 Top 10 Functional Food Trends Food Technology Volume 60 No 4

BioBest Omega 3 probiotic yogurt is a source of omega-3 PUFA that are considered an important part of a healthy diet It also contains over 1 billion active probiotic cultures Lactobacillus acidophilus NCFM Bifidobacterium lactis Bi-07 per serving that contribute to healthy digestive tract flora httpwwwastrocaproductsbiobest_omega_3_12x100g_multipackUbJJb_nVA8s

Functional food components ndash Omega 3

Inhibition of β-carotene degradation in oil-in-water nanoemulsions Influence of oil-soluble and water-soluble antioxidants Cheng Qian Eric Andrew Decker Hang Xiao David Julian McClements Volume 135 Issue 3 1 December 2012 Pages 1036ndash1043

Functional food components ndash Carotenoids

β-carotene enriched oil-in-water nanoemulsions stabilized by different emulsifiers with either no antioxidants (control) or antioxidants (80 μM EDTA + 10000 ppm vitamin E acetate)

Functional food components ndash Polyphenols

Pomegranate Phenolics from the Peels Arils and Flowers Are Antiatherogenic Studies in Vivo in Atherosclerotic Apolipoprotein E-Deficient (E0) Mice and in Vitro in Cultured Macrophages and Lipoproteins J Agric Food Chem 2008 56 (3) pp 1148ndash1157

Pomegranate phenolics and mainly oligomers punicalagin punicalin and gallic and ellagic acids are major contributors to the beneficial effects of pomegranate juice

Functional food components ndash Antioxidant activity

J Med Food 2012 Nov15(11)968-73 doi 101089jmf20122282 Epub 2012 Oct 12 Prickly pear cactus (Opuntia ficus indica var saboten) protects against stress-induced acute gastric lesions in rats (maltodextrin y betanin)

httpcancerpreventionresearchaacrjournalsorgcontentearly200906191940-6207CAPR-08-0167abstract

Tea Polyphenols Decrease Serum Levels of Prostate-Specific Antigen Hepatocyte Growth Factor and Vascular Endothelial Growth Factor in Prostate Cancer Patients and Inhibit Production of Hepatocyte Growth Factor and Vascular Endothelial Growth Factor In vitro 2008 Jerry McLarty Rebecca LH Bigelow Mylinh Smith Don Elmajian Murali Ankem James A Cardelli

Functional food components ndash Polyphenols

ldquoNano-sized self assembled structured liquids = nanodrops Liquid carriers that pass through the digestive system effectively without sinking or breaking up to the absorption site These nanodrops carry the phytosterols to the large micelles that the body produces from the bile acid where they compete with cholesterol for entry into the micelle The phytosterols enter the micelle thereby inhibiting transportation of cholesterol from the digestive system into the bloodstreamrdquo Shemen Industries

Functional food components ndash Phytosterols

Goacutemez-Guilleacuten M C B Gimeacutenez et al (2011) Functional and bioactive properties of collagen and gelatin from alternative sources A review Food Hydrocolloids 25(8) 1813-1827

Functional food components ndash Bioactive peptides

httpwwwnuritascomscreening-mining-food-for-bioactive-peptides

Health and nutrition benefits associated with Fibregum its fermentation in the large bowel increases levels of beneficial bacteria which stimulates the production of short-chain fatty acids (SCFAs) that have such properties as lowering serum cholesterol it is a strong prebiotic helping to balance the intestinal microbial ecosystem in the distal colon

Functional food components ndash Prebiotic fiber

httpwwwnexiracomFibregumE284A2-healthy-prebiotic-fiber_6html

Senegalia senegal (acacia)

Functional food components ndash Essential minerals (Fe Zn Ca Se)

httpwwwfdagovFoodGuidanceRegulationGuidanceDocumentsRegulatoryInformationLabelingNutritionucm152626htm

Pseudocereals are considered an important energy source due to their starch content they also provide good quality protein dietary fibre and lipids rich in unsaturated fats They contain adequate levels of minerals and vitamins and significant amounts of other bioactive components such as saponins phytosterols squalene fagopyritols and polyphenols

Functional food components ndash micronutrients

httpquinuapewp-contentuploads201302antiox-Gallagherpdf

Seven-step process would ensure that functional foods are safe and effective with health claims that are accurate and regulatory oversight that is science based and efficient

Functional foods

FERGUS CLYDESDALE 2004 Functional Foods Opportunities amp Challenges Food Technology December 2004 Volume 58 No12

httpwwwgooglecompatentsUS20100196569

httpwwwgooglecompatentsWO2006048158A1cl=en

httpswwwgooglecompatentsUS6428824pg=PA2ampdq=Lepidium+peruvianumamphl=enampsa=Xampei=KxK2UanpKvOu4AOehICgDwampved=0CDoQ6AEwATgK

httpswwwgooglecompatentsUS7005148pg=PA3ampdq=vaccinium+corymbosumamphl=enampsa=Xampei=-xK2UZ7vF_a64AO0soG4Cgampsqi=2amppjf=1ampved=0CGwQ6AEwCA

httpswwwgooglecompatentsWO2001045648A2cl=enampdq=vaccinium+corymbosumamphl=enampsa=Xampei=9BO2Uc_5A9Sz4AOrsIEIampved=0CDQQ6AEwAA

Potential for future researchhellip

Top health issues consumers are concerned about preventing From NMI(2005)

A ELIZABETH SLOAN 2006 Top 10 Functional Food Trends Food Technology Volume 60 No 4

Inhibition of β-carotene degradation in oil-in-water nanoemulsions Influence of oil-soluble and water-soluble antioxidants Cheng Qian Eric Andrew Decker Hang Xiao David Julian McClements Volume 135 Issue 3 1 December 2012 Pages 1036ndash1043

Functional food components ndash Carotenoids

β-carotene enriched oil-in-water nanoemulsions stabilized by different emulsifiers with either no antioxidants (control) or antioxidants (80 μM EDTA + 10000 ppm vitamin E acetate)

Functional food components ndash Polyphenols

Pomegranate Phenolics from the Peels Arils and Flowers Are Antiatherogenic Studies in Vivo in Atherosclerotic Apolipoprotein E-Deficient (E0) Mice and in Vitro in Cultured Macrophages and Lipoproteins J Agric Food Chem 2008 56 (3) pp 1148ndash1157

Pomegranate phenolics and mainly oligomers punicalagin punicalin and gallic and ellagic acids are major contributors to the beneficial effects of pomegranate juice

Functional food components ndash Antioxidant activity

J Med Food 2012 Nov15(11)968-73 doi 101089jmf20122282 Epub 2012 Oct 12 Prickly pear cactus (Opuntia ficus indica var saboten) protects against stress-induced acute gastric lesions in rats (maltodextrin y betanin)

httpcancerpreventionresearchaacrjournalsorgcontentearly200906191940-6207CAPR-08-0167abstract

Tea Polyphenols Decrease Serum Levels of Prostate-Specific Antigen Hepatocyte Growth Factor and Vascular Endothelial Growth Factor in Prostate Cancer Patients and Inhibit Production of Hepatocyte Growth Factor and Vascular Endothelial Growth Factor In vitro 2008 Jerry McLarty Rebecca LH Bigelow Mylinh Smith Don Elmajian Murali Ankem James A Cardelli

Functional food components ndash Polyphenols

ldquoNano-sized self assembled structured liquids = nanodrops Liquid carriers that pass through the digestive system effectively without sinking or breaking up to the absorption site These nanodrops carry the phytosterols to the large micelles that the body produces from the bile acid where they compete with cholesterol for entry into the micelle The phytosterols enter the micelle thereby inhibiting transportation of cholesterol from the digestive system into the bloodstreamrdquo Shemen Industries

Functional food components ndash Phytosterols

Goacutemez-Guilleacuten M C B Gimeacutenez et al (2011) Functional and bioactive properties of collagen and gelatin from alternative sources A review Food Hydrocolloids 25(8) 1813-1827

Functional food components ndash Bioactive peptides

httpwwwnuritascomscreening-mining-food-for-bioactive-peptides

Health and nutrition benefits associated with Fibregum its fermentation in the large bowel increases levels of beneficial bacteria which stimulates the production of short-chain fatty acids (SCFAs) that have such properties as lowering serum cholesterol it is a strong prebiotic helping to balance the intestinal microbial ecosystem in the distal colon

Functional food components ndash Prebiotic fiber

httpwwwnexiracomFibregumE284A2-healthy-prebiotic-fiber_6html

Senegalia senegal (acacia)

Functional food components ndash Essential minerals (Fe Zn Ca Se)

httpwwwfdagovFoodGuidanceRegulationGuidanceDocumentsRegulatoryInformationLabelingNutritionucm152626htm

Pseudocereals are considered an important energy source due to their starch content they also provide good quality protein dietary fibre and lipids rich in unsaturated fats They contain adequate levels of minerals and vitamins and significant amounts of other bioactive components such as saponins phytosterols squalene fagopyritols and polyphenols

Functional food components ndash micronutrients

httpquinuapewp-contentuploads201302antiox-Gallagherpdf

Seven-step process would ensure that functional foods are safe and effective with health claims that are accurate and regulatory oversight that is science based and efficient

Functional foods

FERGUS CLYDESDALE 2004 Functional Foods Opportunities amp Challenges Food Technology December 2004 Volume 58 No12

httpwwwgooglecompatentsUS20100196569

httpwwwgooglecompatentsWO2006048158A1cl=en

httpswwwgooglecompatentsUS6428824pg=PA2ampdq=Lepidium+peruvianumamphl=enampsa=Xampei=KxK2UanpKvOu4AOehICgDwampved=0CDoQ6AEwATgK

httpswwwgooglecompatentsUS7005148pg=PA3ampdq=vaccinium+corymbosumamphl=enampsa=Xampei=-xK2UZ7vF_a64AO0soG4Cgampsqi=2amppjf=1ampved=0CGwQ6AEwCA

httpswwwgooglecompatentsWO2001045648A2cl=enampdq=vaccinium+corymbosumamphl=enampsa=Xampei=9BO2Uc_5A9Sz4AOrsIEIampved=0CDQQ6AEwAA

Potential for future researchhellip

Top health issues consumers are concerned about preventing From NMI(2005)

A ELIZABETH SLOAN 2006 Top 10 Functional Food Trends Food Technology Volume 60 No 4

Functional food components ndash Polyphenols

Pomegranate Phenolics from the Peels Arils and Flowers Are Antiatherogenic Studies in Vivo in Atherosclerotic Apolipoprotein E-Deficient (E0) Mice and in Vitro in Cultured Macrophages and Lipoproteins J Agric Food Chem 2008 56 (3) pp 1148ndash1157

Pomegranate phenolics and mainly oligomers punicalagin punicalin and gallic and ellagic acids are major contributors to the beneficial effects of pomegranate juice

Functional food components ndash Antioxidant activity

J Med Food 2012 Nov15(11)968-73 doi 101089jmf20122282 Epub 2012 Oct 12 Prickly pear cactus (Opuntia ficus indica var saboten) protects against stress-induced acute gastric lesions in rats (maltodextrin y betanin)

httpcancerpreventionresearchaacrjournalsorgcontentearly200906191940-6207CAPR-08-0167abstract

Tea Polyphenols Decrease Serum Levels of Prostate-Specific Antigen Hepatocyte Growth Factor and Vascular Endothelial Growth Factor in Prostate Cancer Patients and Inhibit Production of Hepatocyte Growth Factor and Vascular Endothelial Growth Factor In vitro 2008 Jerry McLarty Rebecca LH Bigelow Mylinh Smith Don Elmajian Murali Ankem James A Cardelli

Functional food components ndash Polyphenols

ldquoNano-sized self assembled structured liquids = nanodrops Liquid carriers that pass through the digestive system effectively without sinking or breaking up to the absorption site These nanodrops carry the phytosterols to the large micelles that the body produces from the bile acid where they compete with cholesterol for entry into the micelle The phytosterols enter the micelle thereby inhibiting transportation of cholesterol from the digestive system into the bloodstreamrdquo Shemen Industries

Functional food components ndash Phytosterols

Goacutemez-Guilleacuten M C B Gimeacutenez et al (2011) Functional and bioactive properties of collagen and gelatin from alternative sources A review Food Hydrocolloids 25(8) 1813-1827

Functional food components ndash Bioactive peptides

httpwwwnuritascomscreening-mining-food-for-bioactive-peptides

Health and nutrition benefits associated with Fibregum its fermentation in the large bowel increases levels of beneficial bacteria which stimulates the production of short-chain fatty acids (SCFAs) that have such properties as lowering serum cholesterol it is a strong prebiotic helping to balance the intestinal microbial ecosystem in the distal colon

Functional food components ndash Prebiotic fiber

httpwwwnexiracomFibregumE284A2-healthy-prebiotic-fiber_6html

Senegalia senegal (acacia)

Functional food components ndash Essential minerals (Fe Zn Ca Se)

httpwwwfdagovFoodGuidanceRegulationGuidanceDocumentsRegulatoryInformationLabelingNutritionucm152626htm

Pseudocereals are considered an important energy source due to their starch content they also provide good quality protein dietary fibre and lipids rich in unsaturated fats They contain adequate levels of minerals and vitamins and significant amounts of other bioactive components such as saponins phytosterols squalene fagopyritols and polyphenols

Functional food components ndash micronutrients

httpquinuapewp-contentuploads201302antiox-Gallagherpdf

Seven-step process would ensure that functional foods are safe and effective with health claims that are accurate and regulatory oversight that is science based and efficient

Functional foods

FERGUS CLYDESDALE 2004 Functional Foods Opportunities amp Challenges Food Technology December 2004 Volume 58 No12

httpwwwgooglecompatentsUS20100196569

httpwwwgooglecompatentsWO2006048158A1cl=en

httpswwwgooglecompatentsUS6428824pg=PA2ampdq=Lepidium+peruvianumamphl=enampsa=Xampei=KxK2UanpKvOu4AOehICgDwampved=0CDoQ6AEwATgK

httpswwwgooglecompatentsUS7005148pg=PA3ampdq=vaccinium+corymbosumamphl=enampsa=Xampei=-xK2UZ7vF_a64AO0soG4Cgampsqi=2amppjf=1ampved=0CGwQ6AEwCA

httpswwwgooglecompatentsWO2001045648A2cl=enampdq=vaccinium+corymbosumamphl=enampsa=Xampei=9BO2Uc_5A9Sz4AOrsIEIampved=0CDQQ6AEwAA

Potential for future researchhellip

Top health issues consumers are concerned about preventing From NMI(2005)

A ELIZABETH SLOAN 2006 Top 10 Functional Food Trends Food Technology Volume 60 No 4

Functional food components ndash Antioxidant activity

J Med Food 2012 Nov15(11)968-73 doi 101089jmf20122282 Epub 2012 Oct 12 Prickly pear cactus (Opuntia ficus indica var saboten) protects against stress-induced acute gastric lesions in rats (maltodextrin y betanin)

httpcancerpreventionresearchaacrjournalsorgcontentearly200906191940-6207CAPR-08-0167abstract

Tea Polyphenols Decrease Serum Levels of Prostate-Specific Antigen Hepatocyte Growth Factor and Vascular Endothelial Growth Factor in Prostate Cancer Patients and Inhibit Production of Hepatocyte Growth Factor and Vascular Endothelial Growth Factor In vitro 2008 Jerry McLarty Rebecca LH Bigelow Mylinh Smith Don Elmajian Murali Ankem James A Cardelli

Functional food components ndash Polyphenols

ldquoNano-sized self assembled structured liquids = nanodrops Liquid carriers that pass through the digestive system effectively without sinking or breaking up to the absorption site These nanodrops carry the phytosterols to the large micelles that the body produces from the bile acid where they compete with cholesterol for entry into the micelle The phytosterols enter the micelle thereby inhibiting transportation of cholesterol from the digestive system into the bloodstreamrdquo Shemen Industries

Functional food components ndash Phytosterols

Goacutemez-Guilleacuten M C B Gimeacutenez et al (2011) Functional and bioactive properties of collagen and gelatin from alternative sources A review Food Hydrocolloids 25(8) 1813-1827

Functional food components ndash Bioactive peptides

httpwwwnuritascomscreening-mining-food-for-bioactive-peptides

Health and nutrition benefits associated with Fibregum its fermentation in the large bowel increases levels of beneficial bacteria which stimulates the production of short-chain fatty acids (SCFAs) that have such properties as lowering serum cholesterol it is a strong prebiotic helping to balance the intestinal microbial ecosystem in the distal colon

Functional food components ndash Prebiotic fiber

httpwwwnexiracomFibregumE284A2-healthy-prebiotic-fiber_6html

Senegalia senegal (acacia)

Functional food components ndash Essential minerals (Fe Zn Ca Se)

httpwwwfdagovFoodGuidanceRegulationGuidanceDocumentsRegulatoryInformationLabelingNutritionucm152626htm

Pseudocereals are considered an important energy source due to their starch content they also provide good quality protein dietary fibre and lipids rich in unsaturated fats They contain adequate levels of minerals and vitamins and significant amounts of other bioactive components such as saponins phytosterols squalene fagopyritols and polyphenols

Functional food components ndash micronutrients

httpquinuapewp-contentuploads201302antiox-Gallagherpdf

Seven-step process would ensure that functional foods are safe and effective with health claims that are accurate and regulatory oversight that is science based and efficient

Functional foods

FERGUS CLYDESDALE 2004 Functional Foods Opportunities amp Challenges Food Technology December 2004 Volume 58 No12

httpwwwgooglecompatentsUS20100196569

httpwwwgooglecompatentsWO2006048158A1cl=en

httpswwwgooglecompatentsUS6428824pg=PA2ampdq=Lepidium+peruvianumamphl=enampsa=Xampei=KxK2UanpKvOu4AOehICgDwampved=0CDoQ6AEwATgK

httpswwwgooglecompatentsUS7005148pg=PA3ampdq=vaccinium+corymbosumamphl=enampsa=Xampei=-xK2UZ7vF_a64AO0soG4Cgampsqi=2amppjf=1ampved=0CGwQ6AEwCA

httpswwwgooglecompatentsWO2001045648A2cl=enampdq=vaccinium+corymbosumamphl=enampsa=Xampei=9BO2Uc_5A9Sz4AOrsIEIampved=0CDQQ6AEwAA

Potential for future researchhellip

Top health issues consumers are concerned about preventing From NMI(2005)

A ELIZABETH SLOAN 2006 Top 10 Functional Food Trends Food Technology Volume 60 No 4

httpcancerpreventionresearchaacrjournalsorgcontentearly200906191940-6207CAPR-08-0167abstract

Tea Polyphenols Decrease Serum Levels of Prostate-Specific Antigen Hepatocyte Growth Factor and Vascular Endothelial Growth Factor in Prostate Cancer Patients and Inhibit Production of Hepatocyte Growth Factor and Vascular Endothelial Growth Factor In vitro 2008 Jerry McLarty Rebecca LH Bigelow Mylinh Smith Don Elmajian Murali Ankem James A Cardelli

Functional food components ndash Polyphenols

ldquoNano-sized self assembled structured liquids = nanodrops Liquid carriers that pass through the digestive system effectively without sinking or breaking up to the absorption site These nanodrops carry the phytosterols to the large micelles that the body produces from the bile acid where they compete with cholesterol for entry into the micelle The phytosterols enter the micelle thereby inhibiting transportation of cholesterol from the digestive system into the bloodstreamrdquo Shemen Industries

Functional food components ndash Phytosterols

Goacutemez-Guilleacuten M C B Gimeacutenez et al (2011) Functional and bioactive properties of collagen and gelatin from alternative sources A review Food Hydrocolloids 25(8) 1813-1827

Functional food components ndash Bioactive peptides

httpwwwnuritascomscreening-mining-food-for-bioactive-peptides

Health and nutrition benefits associated with Fibregum its fermentation in the large bowel increases levels of beneficial bacteria which stimulates the production of short-chain fatty acids (SCFAs) that have such properties as lowering serum cholesterol it is a strong prebiotic helping to balance the intestinal microbial ecosystem in the distal colon

Functional food components ndash Prebiotic fiber

httpwwwnexiracomFibregumE284A2-healthy-prebiotic-fiber_6html

Senegalia senegal (acacia)

Functional food components ndash Essential minerals (Fe Zn Ca Se)

httpwwwfdagovFoodGuidanceRegulationGuidanceDocumentsRegulatoryInformationLabelingNutritionucm152626htm

Pseudocereals are considered an important energy source due to their starch content they also provide good quality protein dietary fibre and lipids rich in unsaturated fats They contain adequate levels of minerals and vitamins and significant amounts of other bioactive components such as saponins phytosterols squalene fagopyritols and polyphenols

Functional food components ndash micronutrients

httpquinuapewp-contentuploads201302antiox-Gallagherpdf

Seven-step process would ensure that functional foods are safe and effective with health claims that are accurate and regulatory oversight that is science based and efficient

Functional foods

FERGUS CLYDESDALE 2004 Functional Foods Opportunities amp Challenges Food Technology December 2004 Volume 58 No12

httpwwwgooglecompatentsUS20100196569

httpwwwgooglecompatentsWO2006048158A1cl=en

httpswwwgooglecompatentsUS6428824pg=PA2ampdq=Lepidium+peruvianumamphl=enampsa=Xampei=KxK2UanpKvOu4AOehICgDwampved=0CDoQ6AEwATgK

httpswwwgooglecompatentsUS7005148pg=PA3ampdq=vaccinium+corymbosumamphl=enampsa=Xampei=-xK2UZ7vF_a64AO0soG4Cgampsqi=2amppjf=1ampved=0CGwQ6AEwCA

httpswwwgooglecompatentsWO2001045648A2cl=enampdq=vaccinium+corymbosumamphl=enampsa=Xampei=9BO2Uc_5A9Sz4AOrsIEIampved=0CDQQ6AEwAA

Potential for future researchhellip

Top health issues consumers are concerned about preventing From NMI(2005)

A ELIZABETH SLOAN 2006 Top 10 Functional Food Trends Food Technology Volume 60 No 4

ldquoNano-sized self assembled structured liquids = nanodrops Liquid carriers that pass through the digestive system effectively without sinking or breaking up to the absorption site These nanodrops carry the phytosterols to the large micelles that the body produces from the bile acid where they compete with cholesterol for entry into the micelle The phytosterols enter the micelle thereby inhibiting transportation of cholesterol from the digestive system into the bloodstreamrdquo Shemen Industries

Functional food components ndash Phytosterols

Goacutemez-Guilleacuten M C B Gimeacutenez et al (2011) Functional and bioactive properties of collagen and gelatin from alternative sources A review Food Hydrocolloids 25(8) 1813-1827

Functional food components ndash Bioactive peptides

httpwwwnuritascomscreening-mining-food-for-bioactive-peptides

Health and nutrition benefits associated with Fibregum its fermentation in the large bowel increases levels of beneficial bacteria which stimulates the production of short-chain fatty acids (SCFAs) that have such properties as lowering serum cholesterol it is a strong prebiotic helping to balance the intestinal microbial ecosystem in the distal colon

Functional food components ndash Prebiotic fiber

httpwwwnexiracomFibregumE284A2-healthy-prebiotic-fiber_6html

Senegalia senegal (acacia)

Functional food components ndash Essential minerals (Fe Zn Ca Se)

httpwwwfdagovFoodGuidanceRegulationGuidanceDocumentsRegulatoryInformationLabelingNutritionucm152626htm

Pseudocereals are considered an important energy source due to their starch content they also provide good quality protein dietary fibre and lipids rich in unsaturated fats They contain adequate levels of minerals and vitamins and significant amounts of other bioactive components such as saponins phytosterols squalene fagopyritols and polyphenols

Functional food components ndash micronutrients

httpquinuapewp-contentuploads201302antiox-Gallagherpdf

Seven-step process would ensure that functional foods are safe and effective with health claims that are accurate and regulatory oversight that is science based and efficient

Functional foods

FERGUS CLYDESDALE 2004 Functional Foods Opportunities amp Challenges Food Technology December 2004 Volume 58 No12

httpwwwgooglecompatentsUS20100196569

httpwwwgooglecompatentsWO2006048158A1cl=en

httpswwwgooglecompatentsUS6428824pg=PA2ampdq=Lepidium+peruvianumamphl=enampsa=Xampei=KxK2UanpKvOu4AOehICgDwampved=0CDoQ6AEwATgK

httpswwwgooglecompatentsUS7005148pg=PA3ampdq=vaccinium+corymbosumamphl=enampsa=Xampei=-xK2UZ7vF_a64AO0soG4Cgampsqi=2amppjf=1ampved=0CGwQ6AEwCA

httpswwwgooglecompatentsWO2001045648A2cl=enampdq=vaccinium+corymbosumamphl=enampsa=Xampei=9BO2Uc_5A9Sz4AOrsIEIampved=0CDQQ6AEwAA

Potential for future researchhellip

Top health issues consumers are concerned about preventing From NMI(2005)

A ELIZABETH SLOAN 2006 Top 10 Functional Food Trends Food Technology Volume 60 No 4

Goacutemez-Guilleacuten M C B Gimeacutenez et al (2011) Functional and bioactive properties of collagen and gelatin from alternative sources A review Food Hydrocolloids 25(8) 1813-1827

Functional food components ndash Bioactive peptides

httpwwwnuritascomscreening-mining-food-for-bioactive-peptides

Health and nutrition benefits associated with Fibregum its fermentation in the large bowel increases levels of beneficial bacteria which stimulates the production of short-chain fatty acids (SCFAs) that have such properties as lowering serum cholesterol it is a strong prebiotic helping to balance the intestinal microbial ecosystem in the distal colon

Functional food components ndash Prebiotic fiber

httpwwwnexiracomFibregumE284A2-healthy-prebiotic-fiber_6html

Senegalia senegal (acacia)

Functional food components ndash Essential minerals (Fe Zn Ca Se)

httpwwwfdagovFoodGuidanceRegulationGuidanceDocumentsRegulatoryInformationLabelingNutritionucm152626htm

Pseudocereals are considered an important energy source due to their starch content they also provide good quality protein dietary fibre and lipids rich in unsaturated fats They contain adequate levels of minerals and vitamins and significant amounts of other bioactive components such as saponins phytosterols squalene fagopyritols and polyphenols

Functional food components ndash micronutrients

httpquinuapewp-contentuploads201302antiox-Gallagherpdf

Seven-step process would ensure that functional foods are safe and effective with health claims that are accurate and regulatory oversight that is science based and efficient

Functional foods

FERGUS CLYDESDALE 2004 Functional Foods Opportunities amp Challenges Food Technology December 2004 Volume 58 No12

httpwwwgooglecompatentsUS20100196569

httpwwwgooglecompatentsWO2006048158A1cl=en

httpswwwgooglecompatentsUS6428824pg=PA2ampdq=Lepidium+peruvianumamphl=enampsa=Xampei=KxK2UanpKvOu4AOehICgDwampved=0CDoQ6AEwATgK

httpswwwgooglecompatentsUS7005148pg=PA3ampdq=vaccinium+corymbosumamphl=enampsa=Xampei=-xK2UZ7vF_a64AO0soG4Cgampsqi=2amppjf=1ampved=0CGwQ6AEwCA

httpswwwgooglecompatentsWO2001045648A2cl=enampdq=vaccinium+corymbosumamphl=enampsa=Xampei=9BO2Uc_5A9Sz4AOrsIEIampved=0CDQQ6AEwAA

Potential for future researchhellip

Top health issues consumers are concerned about preventing From NMI(2005)

A ELIZABETH SLOAN 2006 Top 10 Functional Food Trends Food Technology Volume 60 No 4

Health and nutrition benefits associated with Fibregum its fermentation in the large bowel increases levels of beneficial bacteria which stimulates the production of short-chain fatty acids (SCFAs) that have such properties as lowering serum cholesterol it is a strong prebiotic helping to balance the intestinal microbial ecosystem in the distal colon

Functional food components ndash Prebiotic fiber

httpwwwnexiracomFibregumE284A2-healthy-prebiotic-fiber_6html

Senegalia senegal (acacia)

Functional food components ndash Essential minerals (Fe Zn Ca Se)

httpwwwfdagovFoodGuidanceRegulationGuidanceDocumentsRegulatoryInformationLabelingNutritionucm152626htm

Pseudocereals are considered an important energy source due to their starch content they also provide good quality protein dietary fibre and lipids rich in unsaturated fats They contain adequate levels of minerals and vitamins and significant amounts of other bioactive components such as saponins phytosterols squalene fagopyritols and polyphenols

Functional food components ndash micronutrients

httpquinuapewp-contentuploads201302antiox-Gallagherpdf

Seven-step process would ensure that functional foods are safe and effective with health claims that are accurate and regulatory oversight that is science based and efficient

Functional foods

FERGUS CLYDESDALE 2004 Functional Foods Opportunities amp Challenges Food Technology December 2004 Volume 58 No12

httpwwwgooglecompatentsUS20100196569

httpwwwgooglecompatentsWO2006048158A1cl=en

httpswwwgooglecompatentsUS6428824pg=PA2ampdq=Lepidium+peruvianumamphl=enampsa=Xampei=KxK2UanpKvOu4AOehICgDwampved=0CDoQ6AEwATgK

httpswwwgooglecompatentsUS7005148pg=PA3ampdq=vaccinium+corymbosumamphl=enampsa=Xampei=-xK2UZ7vF_a64AO0soG4Cgampsqi=2amppjf=1ampved=0CGwQ6AEwCA

httpswwwgooglecompatentsWO2001045648A2cl=enampdq=vaccinium+corymbosumamphl=enampsa=Xampei=9BO2Uc_5A9Sz4AOrsIEIampved=0CDQQ6AEwAA

Potential for future researchhellip

Top health issues consumers are concerned about preventing From NMI(2005)

A ELIZABETH SLOAN 2006 Top 10 Functional Food Trends Food Technology Volume 60 No 4

Functional food components ndash Essential minerals (Fe Zn Ca Se)

httpwwwfdagovFoodGuidanceRegulationGuidanceDocumentsRegulatoryInformationLabelingNutritionucm152626htm

Pseudocereals are considered an important energy source due to their starch content they also provide good quality protein dietary fibre and lipids rich in unsaturated fats They contain adequate levels of minerals and vitamins and significant amounts of other bioactive components such as saponins phytosterols squalene fagopyritols and polyphenols

Functional food components ndash micronutrients

httpquinuapewp-contentuploads201302antiox-Gallagherpdf

Seven-step process would ensure that functional foods are safe and effective with health claims that are accurate and regulatory oversight that is science based and efficient

Functional foods

FERGUS CLYDESDALE 2004 Functional Foods Opportunities amp Challenges Food Technology December 2004 Volume 58 No12

httpwwwgooglecompatentsUS20100196569

httpwwwgooglecompatentsWO2006048158A1cl=en

httpswwwgooglecompatentsUS6428824pg=PA2ampdq=Lepidium+peruvianumamphl=enampsa=Xampei=KxK2UanpKvOu4AOehICgDwampved=0CDoQ6AEwATgK

httpswwwgooglecompatentsUS7005148pg=PA3ampdq=vaccinium+corymbosumamphl=enampsa=Xampei=-xK2UZ7vF_a64AO0soG4Cgampsqi=2amppjf=1ampved=0CGwQ6AEwCA

httpswwwgooglecompatentsWO2001045648A2cl=enampdq=vaccinium+corymbosumamphl=enampsa=Xampei=9BO2Uc_5A9Sz4AOrsIEIampved=0CDQQ6AEwAA

Potential for future researchhellip

Top health issues consumers are concerned about preventing From NMI(2005)

A ELIZABETH SLOAN 2006 Top 10 Functional Food Trends Food Technology Volume 60 No 4

Pseudocereals are considered an important energy source due to their starch content they also provide good quality protein dietary fibre and lipids rich in unsaturated fats They contain adequate levels of minerals and vitamins and significant amounts of other bioactive components such as saponins phytosterols squalene fagopyritols and polyphenols

Functional food components ndash micronutrients

httpquinuapewp-contentuploads201302antiox-Gallagherpdf

Seven-step process would ensure that functional foods are safe and effective with health claims that are accurate and regulatory oversight that is science based and efficient

Functional foods

FERGUS CLYDESDALE 2004 Functional Foods Opportunities amp Challenges Food Technology December 2004 Volume 58 No12

httpwwwgooglecompatentsUS20100196569

httpwwwgooglecompatentsWO2006048158A1cl=en

httpswwwgooglecompatentsUS6428824pg=PA2ampdq=Lepidium+peruvianumamphl=enampsa=Xampei=KxK2UanpKvOu4AOehICgDwampved=0CDoQ6AEwATgK

httpswwwgooglecompatentsUS7005148pg=PA3ampdq=vaccinium+corymbosumamphl=enampsa=Xampei=-xK2UZ7vF_a64AO0soG4Cgampsqi=2amppjf=1ampved=0CGwQ6AEwCA

httpswwwgooglecompatentsWO2001045648A2cl=enampdq=vaccinium+corymbosumamphl=enampsa=Xampei=9BO2Uc_5A9Sz4AOrsIEIampved=0CDQQ6AEwAA

Potential for future researchhellip

Top health issues consumers are concerned about preventing From NMI(2005)

A ELIZABETH SLOAN 2006 Top 10 Functional Food Trends Food Technology Volume 60 No 4

Seven-step process would ensure that functional foods are safe and effective with health claims that are accurate and regulatory oversight that is science based and efficient

Functional foods

FERGUS CLYDESDALE 2004 Functional Foods Opportunities amp Challenges Food Technology December 2004 Volume 58 No12

httpwwwgooglecompatentsUS20100196569

httpwwwgooglecompatentsWO2006048158A1cl=en

httpswwwgooglecompatentsUS6428824pg=PA2ampdq=Lepidium+peruvianumamphl=enampsa=Xampei=KxK2UanpKvOu4AOehICgDwampved=0CDoQ6AEwATgK

httpswwwgooglecompatentsUS7005148pg=PA3ampdq=vaccinium+corymbosumamphl=enampsa=Xampei=-xK2UZ7vF_a64AO0soG4Cgampsqi=2amppjf=1ampved=0CGwQ6AEwCA

httpswwwgooglecompatentsWO2001045648A2cl=enampdq=vaccinium+corymbosumamphl=enampsa=Xampei=9BO2Uc_5A9Sz4AOrsIEIampved=0CDQQ6AEwAA

Potential for future researchhellip

Top health issues consumers are concerned about preventing From NMI(2005)

A ELIZABETH SLOAN 2006 Top 10 Functional Food Trends Food Technology Volume 60 No 4

httpwwwgooglecompatentsUS20100196569

httpwwwgooglecompatentsWO2006048158A1cl=en

httpswwwgooglecompatentsUS6428824pg=PA2ampdq=Lepidium+peruvianumamphl=enampsa=Xampei=KxK2UanpKvOu4AOehICgDwampved=0CDoQ6AEwATgK

httpswwwgooglecompatentsUS7005148pg=PA3ampdq=vaccinium+corymbosumamphl=enampsa=Xampei=-xK2UZ7vF_a64AO0soG4Cgampsqi=2amppjf=1ampved=0CGwQ6AEwCA

httpswwwgooglecompatentsWO2001045648A2cl=enampdq=vaccinium+corymbosumamphl=enampsa=Xampei=9BO2Uc_5A9Sz4AOrsIEIampved=0CDQQ6AEwAA

Potential for future researchhellip

Top health issues consumers are concerned about preventing From NMI(2005)

A ELIZABETH SLOAN 2006 Top 10 Functional Food Trends Food Technology Volume 60 No 4

Top health issues consumers are concerned about preventing From NMI(2005)

A ELIZABETH SLOAN 2006 Top 10 Functional Food Trends Food Technology Volume 60 No 4


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