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Bio-Intro Lisbeth N. Fink Adjunkt, Nutritional Immunology Group CBS, DTU 1.

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Bio-Intro Lisbeth N. Fink Adjunkt, Nutritional Immunology Group CBS, DTU 1
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Bio-Intro

Lisbeth N. FinkAdjunkt, Nutritional Immunology Group

CBS, DTU

1

DNA

2

Eukaryot >< Prokaryot celle

Ingen introns

3

DNA sequences = summary of information

5’ AGCC 3’3’ TCGG 5’

5’ ATGGCCAGGTAA 3’DNA backbone: http://en.wikipedia.org/wiki/DNA(Deoxy)ribose: http://en.wikipedia.org/

Ribose

1

23

4

5

Deoxyribose

1

23

4

5

5’

3’

5’

3’4

Transkription - afskrivning

5

mRNA-processering

6

Transkription og translation

7

Translation - oversættelse

8

Protein-ladninger

9

Mutationer

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Signalering

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IL-10-signalering

• Cytokiner er proteiner der produceres af (bl.a.) immunceller og virker på (bl.a.) immunceller (leukocytter/hvide blodlegemer)

• IL-10 er et cytokin, der nedregulerer immunrespons, startet af f.eks. en bakterie

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