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BIOEN FAPESP: new knowledge for the future of bioenergy in Brazil Carlos H de Brito Cruz Scientific Director The São Paulo Research Foundation, FAPESP http://www.fapesp.br http://bioenfapesp.org 6/16/2011 bioenergy-in-sp-20110606.pptx;© C.H. Brito Cruz e Fapesp 1
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Page 1: BIOEN FAPESP: new knowledge for the future of bioenergy in ...2011.ethanolsummit.com.br/apresentacoes/pdf/Carlos... · FAPESP: Sugarcane genomics, 1999 •Started 1999 •Molecular

BIOEN FAPESP: new knowledge for the future of bioenergy in Brazil

Carlos H de Brito CruzScientific DirectorThe São Paulo Research Foundation, FAPESPhttp://www.fapesp.brhttp://bioenfapesp.org

6/16/2011 bioenergy-in-sp-20110606.pptx;© C.H. Brito Cruz e Fapesp 1

Page 2: BIOEN FAPESP: new knowledge for the future of bioenergy in ...2011.ethanolsummit.com.br/apresentacoes/pdf/Carlos... · FAPESP: Sugarcane genomics, 1999 •Started 1999 •Molecular

Fapesp: São Paulo Research Foundation

• Mission: support research in all fields• Receives 18,000 proposals per year, all peer reviewed• Funded by the State of São Paulo with 1% of all state tax

revenues• Started operations in 1962• Annual budget: US$ 408 M in 2009

– Fellowships (3,000 SI, 3,000 MS, 3,000 DR, 1,300 PD)– Academic R&D

• Young Investigators

– University-Industry Joint R&D– Small bussiness R&D

• 1,200 SBE’s (three awards per week in 2007)

6/16/2011 bioenergy-in-sp-20110606.pptx;© C.H. Brito Cruz e Fapesp 2

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New challenges for Brazil’s strategy in Bioenergy

• International competition• Stronger scientific base – radical innovation

– Genomics– Bioprocesses– Chemistry, biochemistry

• Science based decision and planning– Sustainability

• Water, fertilizer, energy balance, GHG

– LUC; iLUC

• International presence– High impact scientific publications

6/16/2011 bioenergy-in-sp-20110606.pptx;© C.H. Brito Cruz e Fapesp 3

Page 4: BIOEN FAPESP: new knowledge for the future of bioenergy in ...2011.ethanolsummit.com.br/apresentacoes/pdf/Carlos... · FAPESP: Sugarcane genomics, 1999 •Started 1999 •Molecular

FAPESP and Bioenergy

• First initiative in 1999

– SucEST Project for sugarcane genomics

• Then, three initiatives starting 2007-2008

– Roadmap

– BIOEN

– SP Bioenergy Research Center

6/16/2011 bioenergy-in-sp-20110606.pptx;© C.H. Brito Cruz e Fapesp 4

Page 5: BIOEN FAPESP: new knowledge for the future of bioenergy in ...2011.ethanolsummit.com.br/apresentacoes/pdf/Carlos... · FAPESP: Sugarcane genomics, 1999 •Started 1999 •Molecular

FAPESP: Sugarcane genomics,1999

• Started 1999

• Molecular Biology tools for improving sugarcane

• Science and Technology of sugarcane– Articles, thesis and patents

– Human resources

• Partners:

– CTC and Ridesa

6/16/2011 bioenergy-in-sp-20110606.pptx;© C.H. Brito Cruz e Fapesp 5

Page 6: BIOEN FAPESP: new knowledge for the future of bioenergy in ...2011.ethanolsummit.com.br/apresentacoes/pdf/Carlos... · FAPESP: Sugarcane genomics, 1999 •Started 1999 •Molecular

FAPESP: three articulated initiatives

• Science and Technology bottlenecks– A road map that oriented steps 2 and 3 below

• Research Project; R$ 0,3 million; 14 workshops, >100 researchers; a book published internationally

• BIOEN– Research Program; 5-10 years

• Has a core of fundamental research• Connections to applications through industry partnerships

– 52 projects/100 fellowships (so far, only one CFP – more will follow)• FAPESP: R$ 57 million • Industry: R$ 3,7 million

• São Paulo Bioenergy Research Center– Based in the three State universities: USP, Unicamp, Unesp– Estimated investment: R$ 162 million in 10 years

• GESP: R$ 54 million (already disbursed)• Universities: R$ 54 millions in contracts for new professors in 10 years• FAPESP: R$ 54 million to be disbursed in research grants and fellowships in 10 years

6/16/2011 bioenergy-in-sp-20110606.pptx;© C.H. Brito Cruz e Fapesp 6

Page 7: BIOEN FAPESP: new knowledge for the future of bioenergy in ...2011.ethanolsummit.com.br/apresentacoes/pdf/Carlos... · FAPESP: Sugarcane genomics, 1999 •Started 1999 •Molecular

FAPESP’s Research Program on Bioenergy (BIOEN): 5 divisions

1. Improvements in the feedstock: building a better cane plant for energy –EnergyCane; sugarcane agriculture; other feedstocks

Partner: ETH

2. Production of Ethanol and other products: hydrolysis, pyrolisis, gasification, fermentation, distillation

Partners: Oxiteno, Dedini

3. New processes in alcohol-chemistry

Partners: Braskem

4. Ethanol based engine and fuel cell developments

5. The Economics of Ethanol, Ethanol production and the environment, Social impacts, the new agriculture of food and energy

6/16/2011 bioenergy-in-sp-20110606.pptx;© C.H. Brito Cruz e Fapesp 7

Page 8: BIOEN FAPESP: new knowledge for the future of bioenergy in ...2011.ethanolsummit.com.br/apresentacoes/pdf/Carlos... · FAPESP: Sugarcane genomics, 1999 •Started 1999 •Molecular

BIOEN: FAPESP-Industry agreements for joint funding

• Joint industry-university research (next 5 years)

• Agreement with ETH, Braskem and Dedini will have yearly calls for proposals

Company Subject Val. (Indus.+FAPESP)

Oxiteno Lignocellulosic materials R$ 6,000,000

Braskem Alcohol-chemistry R$ 50,000,000

Dedini Processes R$ 100,000,000

ETH Sugarcane R$ 20,000,000

6/16/2011 bioenergy-in-sp-20110606.pptx;© C.H. Brito Cruz e Fapesp 8

Page 9: BIOEN FAPESP: new knowledge for the future of bioenergy in ...2011.ethanolsummit.com.br/apresentacoes/pdf/Carlos... · FAPESP: Sugarcane genomics, 1999 •Started 1999 •Molecular

BIOEN: 314 scientists

• 55 research projects

– R$ 55 61 million

• 314 scientists

– 229 from São Paulo

– 33 from other Brazilian states

• MG 12; RJ 8; Pr 3; RS 3

– 52 from other countries

• U.S. 26; Fr 7; Ge 4; Ne 4; De 3; Sp 3

6/16/2011 9bioenergy-in-sp-20110606.pptx;© C.H. Brito Cruz e Fapesp

Page 10: BIOEN FAPESP: new knowledge for the future of bioenergy in ...2011.ethanolsummit.com.br/apresentacoes/pdf/Carlos... · FAPESP: Sugarcane genomics, 1999 •Started 1999 •Molecular

Transgenic cane: 9x increased convertionof glucose/fructose into sucrose

bioenergy-in-sp-20110606.pptx;© C.H. Brito Cruz e Fapesp 106/16/2011

USP, Unicamp, CTC, Monsanto, Central de Alcool Lucélia

Page 11: BIOEN FAPESP: new knowledge for the future of bioenergy in ...2011.ethanolsummit.com.br/apresentacoes/pdf/Carlos... · FAPESP: Sugarcane genomics, 1999 •Started 1999 •Molecular

Higher productivity sugarcane:84 → 148 → 212 → 381 ton/Ha??

bioenergy-in-sp-20110606.pptx;© C.H. Brito Cruz e Fapesp 116/16/2011

Page 12: BIOEN FAPESP: new knowledge for the future of bioenergy in ...2011.ethanolsummit.com.br/apresentacoes/pdf/Carlos... · FAPESP: Sugarcane genomics, 1999 •Started 1999 •Molecular

Sugarcane research

6/16/2011 bioenergy-in-sp-20110606.pptx;© C.H. Brito Cruz e Fapesp 12

Page 13: BIOEN FAPESP: new knowledge for the future of bioenergy in ...2011.ethanolsummit.com.br/apresentacoes/pdf/Carlos... · FAPESP: Sugarcane genomics, 1999 •Started 1999 •Molecular

Biofuel research challenges

• Productivity– Biomass production

• 90 ton/Ha → 200+ ton/Ha

– Processes 2nd generation; other fuels; chemicals– Cellulose use (eletricity x liquid fuel)

• Sustainability– Emissions(LUC, ILUC, N)– Water use– Agriculture for Food and for Energy– Environmental impacts– Social impacts

6/16/2011 bioenergy-in-sp-20110606.pptx;© C.H. Brito Cruz e Fapesp 13

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6/16/2011 bioenergy-in-sp-20110606.pptx;© C.H. Brito Cruz e Fapesp 14

Page 15: BIOEN FAPESP: new knowledge for the future of bioenergy in ...2011.ethanolsummit.com.br/apresentacoes/pdf/Carlos... · FAPESP: Sugarcane genomics, 1999 •Started 1999 •Molecular

Some results

• BIOTA Programa oriented State Legislation for Sugarcane Zoning

• Sugarcane in high CO2 environment

• Sugarcane genomics

• Incresase in the number of papers about sugarcane

6/16/2011 bioenergy-in-sp-20110606.pptx;© C.H. Brito Cruz e Fapesp 15

Page 16: BIOEN FAPESP: new knowledge for the future of bioenergy in ...2011.ethanolsummit.com.br/apresentacoes/pdf/Carlos... · FAPESP: Sugarcane genomics, 1999 •Started 1999 •Molecular

Energy sources in the State of São Paulo, Brazil

State of São Paulo• 63% of Brazilian

ethanol

• 41 million people

• 35% of Brazil’s GNP

1980 – 2008

• Oil down from 60%

to 33%

• Cane up from 17%

to 38%

6/16/2011 bioenergy-in-sp-20110606.pptx;© C.H. Brito Cruz e Fapesp 16

Page 17: BIOEN FAPESP: new knowledge for the future of bioenergy in ...2011.ethanolsummit.com.br/apresentacoes/pdf/Carlos... · FAPESP: Sugarcane genomics, 1999 •Started 1999 •Molecular

0

5

10

15

20

25

30

35

40

6 10 13 18 21 26 31 50

Weeks after CO2

A (

µm

ol C

O2 m

-2 s

-1)

Ambiente

Elevado ******

***

*

(a)

Ambient

Elevated

Microarray analyses 5000

genes

Sugarcane in increased CO2

Buckeridge M. Et al. Plant Cell and Environment, vol.31, p. 1116 (2008)

ElevatedAmbient

Productivity

60% more Biomass

6/16/2011 bioenergy-in-sp-20110606.pptx;© C.H. Brito Cruz e Fapesp 17

Page 18: BIOEN FAPESP: new knowledge for the future of bioenergy in ...2011.ethanolsummit.com.br/apresentacoes/pdf/Carlos... · FAPESP: Sugarcane genomics, 1999 •Started 1999 •Molecular

Syntenic regions: rice, sorghum, two cane alleles

Rice

Sorghum

Cane Ssp_148

Cane Ssp_095

Blue, green and red are genes

Grey correspond to repetitive regions

M.Anne van Sluys et al., in preparation

6/16/2011 bioenergy-in-sp-20110606.pptx;© C.H. Brito Cruz e Fapesp 18

Page 19: BIOEN FAPESP: new knowledge for the future of bioenergy in ...2011.ethanolsummit.com.br/apresentacoes/pdf/Carlos... · FAPESP: Sugarcane genomics, 1999 •Started 1999 •Molecular

50 labs

200 researchers

238000 ESTs

43000 Transcripts

SUCEST ProjectFAPESP, 1999 - 2004

6/16/2011 bioenergy-in-sp-20110606.pptx;© C.H. Brito Cruz e Fapesp 19

Page 20: BIOEN FAPESP: new knowledge for the future of bioenergy in ...2011.ethanolsummit.com.br/apresentacoes/pdf/Carlos... · FAPESP: Sugarcane genomics, 1999 •Started 1999 •Molecular

Science based Sugarcane Agroecological Zoning in São Paulo

6/16/2011 bioenergy-in-sp-20110606.pptx;© C.H. Brito Cruz e Fapesp 20

Page 21: BIOEN FAPESP: new knowledge for the future of bioenergy in ...2011.ethanolsummit.com.br/apresentacoes/pdf/Carlos... · FAPESP: Sugarcane genomics, 1999 •Started 1999 •Molecular

State of São Paulo, Brasil

34% of Brazil’s GNP

40 Million people

52% of Brazilian science

13% of State budget to HE

and R&D

1,5% GNP for R&D

3 State Universities

19 Tech Faculties

45% of the PhDs formed in

Brazil (4,500 in 2008)

19 State Research

Institutes

1 Research Foundation

65% of R&D public support

comes from State

sources6/16/2011 bioenergy-in-sp-20110606.pptx;© C.H. Brito Cruz e Fapesp 21


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