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Biomedical Intro

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    BIOMEDICALINSTRUMENTATION

    By: Asst.Prof. Harshul Thakur

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    BIOMEDICALENGINEERING

    Biomedical engineering(BME) is the application of

    engineering.

    This field seeks to close the gap

    between engineeringand medicine.

    It combines the design and problem solving skills of

    engineering with medical and biological sciences to

    advance healthcare treatment,

    including diagnosis, monitoring, and therapy.

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    BIOINSTRUMENTATION

    Bio- of course, denotes something related with life.

    Bio instrumentation implies measurement of biological

    variables.

    Bioinstrumentation is the use of bio-electronic instruments for

    the recording or transmission of physiological information.

    Biomedical Instrumentation involves devices designed and

    connected together in a scientifically appropriate manner to

    sense (or capture) signals (e.g: electromagnetic, mechanical,

    thermal, acoustic) and process them for human display and/orfurther processing for control, therapy etc. like Digital

    Thermometer senses the temp. using electronic sensor then

    filter, amplify and convert into analog quantity and display.

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    KEYROLLS

    BioMedical Engineer A person working in research or development in the

    interface area of medicine and engineering.

    (Develop instruments and measurement devices)

    Clinical Engineer

    A practitioner working with physicians and patient.

    ( Proper use of instruments during patient care)

    Bio Medical Equipment Technician(BMET) A person having knowledge about the theory of

    operation and biomedical equipments.

    (Capabilities like installation, calibration andmaintenance..)

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    MAJORPROBLEM

    Communication gap between engineers and

    medical professionals.

    Development and use of biomedical instruments

    must be a joint effort of engineers or technicians

    and the physician or nurse, every effort must

    consider to avoid or overcome this

    Communication.

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    BIOMETRICS

    The branch of science that includes the measurement

    of physiological variables and parameters is known as

    biometrics. Bio medical instrumentation provides the

    tools by which these measurements can be achieved.

    In the design and specification of medical

    instrumentation system, each of the following factors

    should be considered:

    Range, Sensitivity, Linearity, Hysteresis, Frequency

    Response, Accuracy, S/N ratio, Stability, Isolation and

    Simplicity.

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    RANGE

    The range of an instrument is generally considered to

    include all the levels of input amplitude & frequency

    over which the device is expected to operate.

    The objective is to provide an instrument that will give

    a usable reading from the smallest expected value

    of the variable or parameter being measured to the

    largest.

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    SENSITIVITY

    The sensitivity of an instrument determines how

    small a variation of a variable or parameter can be

    really reliably measured.

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    LINEARITY

    The degree to which variations in the output of an

    instrument follow input variations is referred to as

    the linearity of the device.

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    HYSTERESIS

    It is a characteristic of some instruments where by

    a given value of the measured variable results in a

    different reading when reached in an ascending

    direction from that obtained when it is reached in a

    descending direction .

    (Mechanical friction in a meter)

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    FREQUENCYRESPONSE

    The frequency response of an instrument in its

    variation in sensitivity over the frequency range of

    the measurement. It is important to display a wave

    shape that is a faithful reproduction of the original

    physiological signal.

    An instrument system should be able to respond

    rapidly enough to reproduce all frequency

    components of the waveform with equal sensitivity.

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    ACCURACY

    1. Accuracy

    Closeness to the true value of measurand.

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    ACCURACY

    It is a measure of systemic error. Errors can occur in a multitude ofways. Although not always present simultaneously, the followingerrors should be considered.

    1. Errors due to tolerances of electronic components.2. Mechanical errors in meter movements.3. Component errors due to drift or temperature variations.4. Errors due to poor frequency response.5. Errors due to change in atmospheric pressure or temperature.6. Reading errors due to parallel inadequate illuminations or

    excessively wide ink traces on a pen recording.

    Two additional sources of Errors are

    Correct instrument zeroing or making correct baseline. The effect of the instrument on the parameter to be measured &

    vice versa. ( Specially in measurements in living organism )

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    SIGNALTONOISERATIO

    It is important that the signal to noise ratio be high

    as possible.(Noise due to hospital environment, inferencedue electromagnetic, electrostatic or may be due to poor

    grounding )

    STABILITY

    In control engineering, Stability is the ability of a

    system to resume a steady state conditionsfollowing a disturbance at the input rather than be

    driven into uncontrollable oscillation.

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    ISOLATION

    Instrument does not produce a direct electrical

    contact between subject and ground.

    Electrical Isolation is to be made for avoidinginterference between different instruments used

    simultaneously. It can be achieved by using

    magnetic or optional coupling technique or using

    radio telemetry.

    Telemetry is also used where movement of the

    person or animal to be measured.

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    SIMPLICITY

    All systems & instruments should be as simple as

    possible to eliminate the chance of component or

    human error.

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    PRECISION

    A measure of the degree of agreement within a groupof measurements repeatability of a system-(however no guarantee of accuracy)

    Results have Low scatter excellent precision

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    ADDITIONALFACTORSTHATADDDIFFICULTYOF

    OBTAININGVALIDMEASUREMENT

    1. Safety Considerations.

    2.The environment of the hospital in which these

    measurements are performed.

    3. The medical person usually involved inmeasurements.

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    THEBASICOBJECTIVESOFANYINSTRUMENTATION

    SYSTEMGENERALLYFALLINTOONEOFTHE

    FOLLOWINGCATEGORIES:

    Information Gathering System. To measure natural phenomena.

    Diagnosis System. Measurements are made to detect and correction of some

    malfunction of the system. Classified as Troubleshooting

    equipment. Evaluation System.

    To determine the ability of a system to meet its functionalrequirements. These could classified as proof ofperformance and quality control tests.

    Monitoring System.

    To monitor some process or operation, to obtain continuousinformation about the state.

    Control System. Automatically control of operation of a system based on

    changes in one or more of the internal parameters or in theoutput of the system.

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    BIOMEDICALINSTRUMENTATIONCANGENERALLY

    BECLASSIFIEDINTOTWOMAJORTYPES:

    1. Clinical Instrumentation .

    2.Research Instrumentation.

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    CLINICALINSTRUMENTATION

    Basically devoted to the area of

    Diagnosis

    Patient care

    Treatment of Patients ( Therapeutic use )

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    RESEARCHINSTRUMENTATION

    It is used primarily in the search for new knowledge

    related to various systems that compose the human

    organism.

    Some instruments can be used in both areas.

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    MEASUREMENTS

    Biomedical instrumental measurements aredivided in to two categories.1.In Vivo2.In Vitro

    1. IN VIVO MEASURMENTS In vivo measurementsare made on or within the living organism itself.

    e.g. A device inserted into the blood stream tomeasure the PH of the blood directly.

    2. IN VITRO MEASURMENTS In vitro

    measurements are made outside the body , eventhough it relates to the functions of the body. e.g. Measurements of PH of sample of blood,

    that has been drawn from patients body.

    MAN INSTRUMENTATION SYSTEM

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    MANINSTRUMENTATIONSYSTEM

    A Measuring systemis required to compare a quantity with astandard or to provide an output that can be related to the quantitybeing measured.

    Components of the Man Instrument System

    Subject: The human being or whom measurements are made.

    Stimulus: That evokes a specific functional reaction in an organ.

    Display

    Recorder

    Signal

    conditioner

    Measurand

    Sensor

    Input Output

    DEFINITIONS

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    DEFINITIONS

    Sensor:is a device that detects a change in a physical stimulusand turns it into a signal which can be measured orrecorded

    A Transducer is a device that transfers power from one system to

    another in the same or in a different form.

    Signal conditioning:Amplifying, wave shaping, filtering, rectifying,

    Display Equipment : The electrical output of a signal

    conditioning equipment must be converted in to form thatcan understand and perceived easily.

    Recorder: To store the measured information andprocess it any time.

    WHY DO WE NEED INSTUMENTATION IN MEDICAL

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    WHY DO WE NEED INSTUMENTATION IN MEDICAL

    FIELD

    Diagnosis and therapy depend heavily on the use of medical

    instrumentation. Like

    ENG(electronystagmography),ECG(electrocardiography),EMG

    (electromyography),ERG(electroratinography

    EEG(electroencephalography),MEG(magnetoencephalography

    ), MRI(magnetic resonance imaging),Analysis of data, its storage and Transmission can be done

    Collection of data qualitative and/or quantitative

    Intelligent control is possible

    Decision making and Treatment planning based on the

    decision

    Wide Operating range and Applications are flexible

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    PHYSIOLOGICALSYSTEMSOFTHEBODY

    To obtain the valid measurements from a living

    human being, it is necessary to have some

    understanding of the subject on which the

    measurements are being made.

    With in the human body can found different types of

    signals each of which communicates with the

    external environment and internally with the other

    systems of the body.

    T

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    TYPESOFSIGNALSTOBEMEASUREDBYBIOMEDICAL

    INSTRUMENTS

    Biomedical signal are those which convey information

    regarding Human body and biomedical instruments detectsand measure those signals. Types of signals are as follows

    Bio-Electric signals :- generated by the cell membrane

    potential .

    Bio- Acoustic Signals :- e.g. blood flow in heart, air flow inlungs generate acoustic signals

    Bio-Mechanical signals :- it includes all types of motion,

    movement, pressure and flow signals. e.g. chest walls

    movement during breathing

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    CONTD.

    Bio- Chemical Signals:- generates from the chemical analysis

    e.g.CO2and O2 pressure. Bio-Magnetic Signals:- very weak signals from heart, brain,

    lungs measured by Magneto-encephalograph.

    Bio-Optical Signals:- Blood oxygenation is obtained by

    measuring the light scattering from tissue at differentwavelength

    Bio-Impedance Signal:- injecting current in a tissue and

    measuring the voltage drop gives us skin resistance, blood

    vol., blood distribution etc.

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    SOURCE OF BIOMEDICAL SIGNALS

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