THE FIRST ANTIOXIDANT SKIN BOOSTER

Boost the beauty of your skin!

Pluryal® Booster is a revolutionary treatment designed to restore the skin vitality and youth.

It is a pure gel composed of hyaluronic acid, a natural ingredient present in our skin and responsible for its “plumpness”. It contains also glycerol, a strong antioxidant and moisturizer.

This perfect composition repairs the skin by restoring its vitality, glow, radiance and plumpness.

With time, external aggressions such as sun, tobacco, pollution or stress leave their marks on your skin. It becomes dull, looses its elasticity, vitality and glow.

Besides, from within, the level of hyaluronic acid decreases.

The quality of your skin hence changes. Its texture is no longer comparable to what it was when you were younger.

WHY DO YOU NEED PLURYAL® BOOSTER?

WHAT IS PLURYAL® BOOSTER?

Today it is possible to restore the youth of the skin naturally, by nourishing it from within, thanks to Pluryal® Booster treatment.

A REVOLUTIONARYTREATMENTFOR A NATURALLYYOUNGER SKIN

WHY CHOOSE PLURYAL® BOOSTER?

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AN EASY PROGRAMTHAT YOUR SKINDESERVES

1 2Pluryal® Booster → EFFICIENCY IS PROVEN

Clinical tests performed by several European physicians have proved the efficiency and natural appearance of Pluryal® Booster treatment.

Pluryal® Booster → INDUCES NATURAL RESULTS

It produces very natural results that make you look younger without having an “artificial” look. This is mainly due to the viscoelastic properties of the product.

→ BENEFITS OF PLURYAL® BOOSTER ON THE SKIN :

The skin looksradiant & healthy

Improved complexion

Wrinkles attenuated

Glowing skin

Restored skin hydration & balance

2 to 3 annual sessions

INITIALTREATMENT PHASE

MAINTENANCETREATMENT PHASE

3 treatmentsat 3 weeks interval

3 4 5Pluryal® Booster → IS SAFE

It is composed of ingredients that are naturally occurring in the body and totally degradable.

Besides, Pluryal® Booster is manufactured according to the highest European standards (GMP and ISO 13485) and has obtained the EC certification.

Pluryal® Booster → OFFERS LONG-LASTING RESULTS

Pluryal® Booster offers durable results, thanks to the use of stabilized hyaluronic acid.

The effects need to be maintained only twice or three times per year, depending on the skin condition and age.

Pluryal® Booster → IS QUICK AND EASY

The Pluryal® Booster treatment is performed in less than 20 minutes and does not require a recuperation period. Besides, it offers you the privilege of instant results.

The treatment consists of:

› An initial course of 3 treatments performed at 3 weeks interval › A maintenance treatment of 2 to 3 annual sessions

ERASESUPERFICIAL LINES

Its very light texture suits particularly areas where the skin is thin: fine lines around the eyes, lips, décolleté and dorsum of the hands.

REPAIRDEHYDRATED SKIN

Hyaluronic acid and glycerol are known for their moisturizing action that repairs dehydrated skin whether due to ageing or to sun exposure.

ATTENUATE FLACCIDITY AND DULLNESS

Hyaluronic acid is known for restoring the plumpness and elasticity of the skin. Glycerol on the other hand is a strong antioxidant that fights free radicals and energizes the skin.

OPTIMIZEPLURYAL® DERMAL FILLERS’ RESULTS Pluryal® Booster can also be used in combination with Pluryal® dermal fillers for homogenizing the rejuvenating effect desired.

WHAT CAN PLURYAL® BOOSTERDO FOR YOU?

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29 Avenue MontereyL-2163 Luxembourg

Phone: +352 26 20 04 06Fax: +352 27 85 88 07info@mdskin-solutions.com

www.pluryal.com

For more information, consult your physician or visit our website:

Feel the difference

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In Luxembourg, MD Skin Solutions develops science-based anti-ageing products, offering strong clinical performance to physicians.

› Dedicated to products for professional use ;

› Specialized in anti-ageing solutions ;

› Compliant with EU standards, EC certification and ISO 13485 ;

› Represented in more than 40 countries.

MD SKIN SOLUTIONS PRODUCT LINES:

A PARTNER YOU CAN TRUST

ABOUT MD SKIN SOLUTIONS

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› Monophasic cross-linked hyaluronic acid ;

› Non-animal (bacterial origin) ;

› Complete range of versatile products: - Pluryal® and Pluryal® Volume dermal fillers ; - Pluryal® Booster skin booster with antioxidant ;

› Based on P.R.E.M.I.U.M. Design Concept ;

› Compliance with the highest sterility assurance ;

› EC and ISO 13485 certifications.

THE SCIENCE BEHIND PLURYAL®

of hyaluronic acid dermal fillersand skin booster

A new generation

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FEEL THE DIFFERENCE… …WITH THE P.R.E.M.I.U.M. DESIGN CONCEPT

PURE Non-animal and purified hyaluronic acid > Maximum tolerance.

RETICULATED Use of BDDE for dermal fillers > Safest and most efficient cross-linking of HA.Use of glycerol for skin booster > Safe and efficient stabilization of HA.

ELASTIC Highest elasticity on the market > Natural results, easiness during use & durable results.

MONOPHASIC Uniform structure with no particles > Natural results (mainly in the lips), no need for over-correction and higher tolerance*.

ISOTONIC pH and osmolarity are adjusted to physiological conditions > Highest tolerance and absence of irritations.

ULTIMATE ERGONOMICS Short, graduated glass syringe - Rotative grip - Luer lock > Better handling, greater comfort & control.

MAXIMUM REMANENCE High viscoelasticity, optimal concentration and reticulation > Better resistance to degradation

The P.R.E.M.I.U.M. Design Concept guarantees the unique characteristics of PLURYAL® products and ensures safe, reliable and durable results for physicians and patients.

Because comfort during the procedure is also very important for both physicians and patients, the P.R.E.M.I.U.M. Design Concept privileges high gel’s elasticity and device’s ergonomics, for smoother injections.

* According to published studies, monophasic hyaluronic acid dermal fillers induced less foreign body granulomas than biphasic hyaluronic acid dermal fillers.

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ENJOY THE PLURYAL® SECURITY… …AND COMFORT DURING INJECTION

Short ergonomic glass syringe (1ml)

Graduated syringe

360° Rotative grip

Luer-Lock security

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Very High gel’s elasticity > Smooth injection

Short glass syringe > Better handling and consistency

Large ergonomic fingers grip (360° rotation) > Increased comfort

Reversed graduated syringe > Control of the volume injected

Luer-lock needle > No waste of product

Homogeneous injection strength > Consistency and control throughout the treatment

PLURYAL® products are manufactured in compliance with ISO 13485 and GMP standards:

› Gel preparation under clean room conditions according to EN ISO 14644.

› Compliance of biocompatibility assessment with guideline EN ISO 10933.

› Purification of hyaluronic acid and removal of oxygen for maximum safety (highest acceptance and biocompatibility).

› Complete control of the hyaluronic acid cross-linking parameters such as temperature, environment, etc.

› Highest sterility assurance level since all products are terminally sterilized in a steam autoclave, which is safer than aseptically filled syringes.

› Very low level of BDDE (cross-linking agent), compliant with the specifications for FDA approval.

› Control of protein’s and endotoxin’s levels during the validation process.

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Pluryal® Booster Pluryal® Pluryal® Volume

CONCENTRATION 18mg/ml 23mg/ml 23mg/ml

CROSS-LINKING Glycerol + BDDE ++ BDDE +++

PROTEINS Traces Traces Traces

ENDOTOXINS < 0.05 EU/g <0.05 EU/g < 0.05 EU/g

MOLECULAR WEIGHT 3 Million Daltons 3 Million Daltons 3 Million Daltons

LEVEL OF INJECTION Superficial dermis Mid dermis Deep dermis

PURPOSE Rehydrate and redensify the skin.

Correct the wrinkles, cutaneous fractures and remodel lips.

Restore the structures of the face (contour, chin, cheeks) and lips.

FREQUENCY OF USE Every 4 - 6 months Every 6 - 9 months Every 12 - 16 months

PACKAGING 2 x 1ml 2 x 1ml 2 x 1ml

A COMPLETE RANGE TO SUPPORT YOUR GROWING PRACTICE

3 PRODUCTS FOR A GLOBAL ANTI-AGEINGAPPROACH

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› Fine Lines› Restoration of hydration, density and glow› Face, neck, neckline, hands

› Glabellar Line › Nasolabial folds› Marionette lines› Lip contour

› Cheek and lip augmentation› Nose reshaping› Mandibular correction› Chin remodeling› Dorsum of the hands

OFFER A COMPLETE TREATMENTWITH ONLY 3 PRODUCTS

PRODUCTS= ALL INDICATIONS

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CLINICAL PROVEN SAFETY & EFFICIENCY

BEFORE AFTER

Ref.BOISNIC S, BEN SLAMA L. Interest of a new anti-ageing treatment combining thetransdermal application with Roller of the Products Mesoline® Refresh and Mesoline® Tight, and the injections of Pluryal®. Journal de Médecine Esthétique et de Chirurgie Dermatologique, Vol. 28, Issue 152, Dec 2011, pp. 225-230.

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Safe, reliableand durable results

for physiciansand patients

29 Avenue Monterey, L-2163 LuxembourgPhone: +352 26 20 04 06 - Fax: +352 27 85 88 07

info@mdskin-solutions.com

www.pluryal.com

PLURYAL® BOOSTER, PLURYAL® and PLURYAL® Volume are medical devices for injectable use, reserved for professional use by habilitated physicians

who have received training for injecting dermal fillers and skin boosters.

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