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GANPAT UNIVERSITY Faculty of Science Teaching and Examination scheme & Syllabus of B.Sc. Chemistry Semester VI Effective from July 2020
GANPAT UNIVERSITY
Faculty of Science
Teaching and Examination scheme
&
Syllabus of
B.Sc. Chemistry
Semester VI
Effective from July 2020
Page 2 of 14
GANPAT UNIVERSITY FACULTY OF SCIENCE
REVISION OF TECHING & EXAMINATION SCHEME AND SYLLABUS Programme Bachelor of science Branch/Spec. Chemistry
Semester VI Academic Council Approved Syllabus (in which the revision is carried out)
Notification No
Date
Effective from Academic Year 2020-21 Effective for the batch Admitted in July 2020
Subject code
Subject Name Revision in Full Syllabus (Yes/No)
Revision in Teaching Scheme(Yes/No)
Revision in Exam Scheme(Yes/No)
Revision in Content (Yes/No)
Percentage of changes if content revision
BCHE6ICH INORGANIC CHEMSIRTY
Yes Yes Yes Yes 100%
BCHE6OCH ORGANIC CHEMISTRY
Yes Yes Yes Yes 100%
BCHE6PCH PHYSICAL CHEMSIRTY
Yes Yes Yes Yes 100%
BCHE6ACH ANALYTICAL CHEMISTRY
Yes Yes Yes Yes 100%
BELE6IDC INDUSTRAIL CHEMISTRY
New Course - - - -
BELE6MDC MEDICINAL CHEMISTRY
New Course - - - -
BELE6BOC BIO-CHEMISTRY New Course - - - -
MOOCs courses from SWAYAM PORTAL
New Course - - - -
NEED OF REVISION:
New Syllabus implemented as per UGC guidelines.
Page 3 of 14
ANPAT UNIVERSITY
FACULTY OF SCIENCE
TEACHING AND EXAMINATION SCHEME Programme Bachelor of Science Branch/Spec. Chemistry
Semester VI
Effective from Academic Year 2020-21 Effective for the batch Admitted in July 2018
Sr. No.
Subject Code
Subject Name
Teaching scheme Examination scheme (Marks)
Credit Hours (per week) Theory Practical
Lecture(DT) Practical(Lab.) Lecture(DT) Practical(Lab.) CE SEE Total CE SEE Total
L TU Total P TW Total L TU Total P TW Total
1 BCHE6ICH INORGANIC CHEMISTRY 3 -- 3 2 2 3 -- 3 3 1 4 40 60 100 40 60 100
2 BCHE6OCH ORGANIC CHEMISTRY 3 -- 3 2 2 3 -- 3 3 1 4 40 60 100 40 60 100
3 BCHE6PCH PHYSICAL CHEMISTRY 3 -- 3 2 2 3 -- 3 3 1 4 40 60 100 40 60 100
4 BCHE6ACH ANALYTICAL CHEMISTRY 3 -- 3 2 2 3 -- 3 3 1 4 40 60 100 40 60 100
5 Elective* 2 -- 2 -- -- 2 -- 2 -- -- -- 40 60 100 -- -- --
Total 14 -- 14 08 08 14 -- 14 12 04 16 200 300 500 160 240 400
*any one subject can be offered from the following list of elective subjects.
Sr. No. Subject Code Subject Name
1 BELE6IDC INDUSTRAIL CHEMISTRY
2 BELE6MDC MEDICINAL CHEMISTRY
3 BELE6BOC BIO-CHEMISTRY
4 MOOC’s courses from SWAYAM PORTAL
Page 4 of 14
GANPAT UNIVERSITY
FACULTY OF SCIENCES
PROGRAMME B.Sc. Branch/Spec. Chemistry
SEMESTER VI Version 2.0.0.0
Effective From Academic Year 2020 Effective for the batch Admitted in July-2018
Subject Code BCHE6ICH Subject Name INORGANIC CHEMISTRY
Teaching Scheme Examination Scheme (Marks)
Per Week Lecture Practical
Total CE SEE Total L Tu P Tw
Credit 03 - 02 05 Theory 40 60 100
Hours 03 - 03 01 07 Practical 40 60 100
Pre-requisites
Before studying Inorganic Chemistry, all students have basic knowledge of coordination, acid base and catalytic chemistry concepts.
Learning Outcome
After the successful completion of the course, students will be able to understand Basics of Inorganic, Coordination chemistry concepts Catalyst, electro catalysis, Fisher and Tropsch synthesis. Acid base, HSAB concepts and Classification of Solvents. To understand the concept of crystal field theory, CFSE concept and splitting of d-orbitals.
Theory Syllabus
Unit Content Hours
01
A. Co-ordination chemistry Reaction, kinetics and mechanism. Trans effect and trans influence, Applications of trans effect in synthesis and analysis. Theories of trans effect: Polarization theory, π- bonding theory, MO theory. Lability, inertness, stability and instability. B. Catalysis General Principles, the language of catalysis, homogeneous and heterogeneous catalysis, Homogeneous catalysis: hydrogenation of alkenes, hydroformylation, methanol carbonylation, Wacker oxidation of alkenes, alkene metathesis, Palladium catalyzed C-C bond forming reactions, asymmetric oxidations. Heterogeneous catalysis: the nature of heterogeneous catalysis, hydrogenation of alkenes, ammonia synthesis, sulfur dioxide oxidation, interconversion of aromatics by zeolites, Fisher and Tropsch synthesis, alkene polymerization, electrocatalysis.
15
02 A. Acids & Bases Arrhenius Concept, Lowry-Bronsted Acid-Base Concept, Solvent System Concept, Usanovich Concept, Luxflood Concept, Lewis Acid-Base Concept, Classification of Lewis Acids and Bases, Pearson’s Soft and Hard Acid-Base Principle (HSAB), Applications of HSAB Principle, Leveling Effect, Strength of Hydraacids, Strength of Inorganic Oxyacids. B. Non-Aqueous Solvents Classification of Solvents, General Properties of Ionizing Solvents, Liquid NH3 as Non-aqueous Solvent, Cavity Model, Alkali Metals in Liquid NH3, Merits and Demerits of Liquid NH3 as Solvent, Liquid SO2 as a Solvent, Liquid Hydrogen Fluoride.
15
03 Crystal Field Theory: Introduction, concept of crystal field theory, splitting of d-orbital in octahedral and tetrahedral crystal field with CFSE concept, factors affecting splitting energy, weak field and strong field ligands, high spin and low spin complexes with pairing energy, magnetic behavior of transition metal complexes, orbital angular momentum contribution to magnetic momentum of complexes, examples based on CFSE, pairing energy and magnetic momentum.
15
Page 5 of 14
Reference Books
1. Principles of Inorganic Chemistry: Puri, Sharma and Kalia 2. Selected Topic in Inorganic Chemistry, Wahid U. Malik, G. D. Tuli and R. D. Madan 3. Introductory Quantum Chemistry- 4th Edition By A K Chandra 4. Advanced Inorganic Chemistry Vol-1, 23rd By Gurdeep Raj 5. Concise Inorganic Chemistry: J. D. Lee; Wiley India. 6. ‘Shriver and Atkins’ Inorganic Chemistry: Atkins, Overton, Rourke, Weller, Armstrong; Oxford
University Press. 7. Inorganic Chemistry, 4th Edition By Shriver & Atkins. 8. Advanced Inorganic Chemistry: F.A. Cotton and Wilkinson G.; John Wiley. 9. Introductory Quantum Chemistry: A. K. Chandra; Tata-McGraw Hill. 10. Advanced Inorganic chemistry: (Vol. 1) Satya Prakash, Tuli, Basu and Madan; S. Chand 11. Basic Inorganic Chemistry- 3rd Edition By F.Albert Cotton, Geoffery Wilkinson & Paul L. Gaus
Practical Syllabus
Sr. No. Content
01 GRAVIMETRIC ANALYSIS 1. Al as Al2O3 2. Fe as Fe2O3 3. Ba as BaSO4 4. Ni as Ni(DMG)2 5. Cr as Cr2O3 6. Zn as Zn2P2O7 7. Mn as Mn2P2O7
VOLUMETRIC ANALYSIS 8. Pb+2 by EDTA 9. Bi+3 by EDTA 10. Ca+2 by EDTA 11. Use of K2Cr 2O7 (Determination of Iron) 12. Iodometry and iodimetry (Determination of Copper, dichromate, Permanganate and
arsenious oxide.)
Reference Books
1. Textbook of quantitative analysis, A. I. Vogel. 2. Textbook of qualitative analysis, A. I. Vogel. 3. Experimental physical chemistry by R. C. Das & B. Bahera 4. Practical in inorganic chemistry & analytical chemistry’, H.G. Raval, Nirav & Rupal Prakashan. 5. A Text Book of Practical Organic Chemistry, A. I. Vogel. 6. Techniques and Experiments for Organic Chemistry. A. Ault 7. Advanced Practical Organic Chemistry. N. K. Vishnoi 8. Laboratory Manual of Organic Chemistry. B. B. Dey and M.V. Sitaraman 9. Laboratory Manual in Organic Chemistry. Raj K. Bansal
Page 6 of 14
GANPAT UNIVERSITY
FACULTY OF SCIENCES
PROGRAMME B.Sc. Branch/Spec. Chemistry
SEMESTER VI Version 2.0.0.0
Effective From Academic Year 2020 Effective for the batch Admitted in July-2018
Subject Code BCHE6OCH Subject Name ORGANIC CHEMISTRY
Teaching Scheme Examination Scheme (Marks)
Per Week Lecture Practical
Total CE SEE Total L Tu P Tw
Credit 03 - 02 05 Theory 40 60 100
Hours 03 - 03 01 07 Practical 40 60 100
Pre-requisites
Before studying organic and analytical chemistry, all students have basic knowledge of stereochemistry, reaction intermediate molecular Electrophilic and free radical addition reaction and Organic structures.
Learning Outcome
After the successful completion of the course, students will be able to understand Basics of Organic, Electrophilic and free radical addition reaction concepts.
Stereochemistry, isomerism and Conformational analysis. Reaction Intermediate and Mechanism , Homo and heterolytic fission
To create interest in students in learning Nucleophilic, Electrophilic and free radical reactions
Theory Syllabus
Unit Content Hours
01
Stereochemistry Introduction, Classification of isomerism, Optical isomerism and Geometrical isomerism, Symmetry elements, Plan polarized light, Optical isomerism due to restrict rotation in biphenyl and allenes, Conformational analysis of Acyclic compound & cyclohexane; Nomenclature of enantiomers, Cis-trans, R-S and E-Z isomerism.
15
02 Reaction Intermediate and Mechanism Homo and heterolytic fission, generation, Fate and stability of carbocations, carbanions, free radicals, carbenes, nitrenes, benzynes and enamines.
15
03 Electrophilic and free radical addition reaction Addition to carbon-carbon double bond, Markovnikov’s rule, Electrophilic addition, Orientation, Reactivity, Rearrangement, Dimerization, Alkylation, Peroxide effect (Anti Markovnikov’s rule); Free radical addition, mechanism of peroxide-initiated addition of HBr, Syn and anti-addition mechanism for addition of halogens, Electrophilic addition to conjugated dienes (1: 2 v/s 1: 4 addition), Free radical addition to conjugated dienes, reactivity Nucleophilic Aromatic Substitutions Nucleophilic aromatic substitution [Bimolecular displacement (SN2) mechanism] Elimination – Addition mechanism via benzyne, Stability and properties of benzyne. Evidences of Benzyne intermediate.
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Reference Books
Page 7 of 14
1. Organic reaction mechanism: An Introduction, Ronald Breslow; Benzamin 2. Organic Chemistry, The fundamental priniciples, I. L. Finar. Pearson. 3. Organic Chemistry, Stereochemistry and the chemistry of Natural Products, I. L. Finar,
Pearson. 4. Organic chemistry, 6th Ed., By Morrison and Boyds. 5. Organic Chemistry, S. M. Mukherji, S. P. Singh and R. P. Kapoor, New Age International (P)
Limited. 6. A textbook of organic chemistry, Arun Bahl, B. S. Bahl, S. Chand. 7. Organic Chemistry, Robert Thornton Morrison and Robert Neilson Boyd, Prentice-Hall of
India Private Limited. 8. March’s Advanced Organic Chemistry Reactions, Mechanism and Structure, Michael B
Smith and Jerry March, Wiley. 9. Reaction Mechanisms and Reagents in Organic Chemistry, Gurudeep R. Chatwal, 10. Organic chemistry, reaction mechanism, V. K. Ahluvalia, R. K. Parashar, Narosa. 11. Organic chemistry of natural products by Gurdeep R. Chatwal, Vol. I. 12. Organic Reaction Mechanism by S.M. Mukherji. 13. Organic Reaction Mechanism by R.K. Bansal. 14. Organic Chemistry by R.O.C. Norman
Practical Syllabus
Sr. No. Content
01 Separation and identification of ternary organic mixture (Solid + solid + solid or solid + solid + liquid or solid + liquid + liquid or liquid + liquid + liquid) (any twelve) Benzoic acid, salicylic acid, cinnamic acid, phthalic acid, α-naphthol, β-naphthol, Nitrobenzene, o-, m-, & p-nitroaniline, acetophenone, p-dichlorobenzene, naphthalene, anthracene, benzamide, acetanilide, m-dinitrobenzene, Methylethylketone, xylene, ethyl acetate, methyl acetate, acetone, aniline, methyl alcohol, ethyl alcohol, benzaldehyde, toluene, chloroform, chlorobenzene, N,N-dimethylaniline. Organic Estimation: Amine, Amide and Aspirin.
Reference Books
1. Textbook of quantitative analysis, A. I. Vogel. 2. Textbook of qualitative analysis, A. I. Vogel. 3. Experimental physical chemistry by R. C. Das & B. Bahera 4. Practical in inorganic chemistry & analytical chemistry’, H.G. Raval, Nirav&RupalPrakashan. 5. A Text Book of Practical Organic Chemistry. A. I. Vogel. 6. Techniques and Experiments for Organic Chemistry. A. Ault 7. Advanced Practical Organic Chemistry. N. K. Vishnoi. 8. Laboratory Manual of Organic Chemistry. B. B. Dey and M.V. Sitaraman 9. Vogel’s Testbook of Quanitative Chemical Analysis, 5 th Edition By G.H.Jeffery, J.Basset,
J.Mendham, R.C.Denney. 10. Practical Chemistry By O.P.Pandey, D.N.Bajpai & S.Giri 11. An Advanced Course In Practical Chemistry By Ghoshal, Mahapatra & Nad
Page 8 of 14
GANPAT UNIVERSITY
FACULTY OF SCIENCES
PROGRAMME B.Sc. Branch/Spec. Chemistry
SEMESTER VI Version 2.0.0.0
Effective From Academic Year 2020 Effective for the batch Admitted in July-2018
Subject Code BCHE6PCH Subject Name PHYSICAL CHEMISTRY
Teaching Scheme Examination Scheme (Marks)
Per Week Lecture Practical
Total CE SEE Total L Tu P Tw
Credit 03 - 02 05 Theory 40 60 100
Hours 03 - 03 01 07 Practical 40 60 100
Pre-requisites
Before studying physical chemistry, all students have basic knowledge of macromolecules, electro chemistry and basics nuclear chemistry concepts.
Learning Outcome
After the successful completion of the course, students will be able to understand Basics of Physical macromolecule and electrochemistry concepts. Polymerization, Classification, mechanism, Osmometry and Viscometry. To create interest in electrochemistry, Electrode concepts and Cell. To create interest in students in learning nuclear and colloidal chemistry.
Theory Syllabus
Unit Content Hours
01
Macromolecules Introduction, Classification of polymers, Nomenclature of polymers, Isomerism of polymers, Chain growth polymerization – Introduction, Mechanism of free-radical, Cationic and Anionic polymerization, Kinetics of free radical, Cationic and Anionic polymerization, Mechanism and Kinetics polycondensation, Polymerization Techniques, Concept of Averages-Number average molecular weight, Weight average molecular weight, Viscosity average molecular weight, Molecular weight and Degree of polymerization, Poly dispersity and molecular weight distribution, Methods for determination of molecular weight, Membrane Osmometry, Vapour Phase Osmometry, Viscometry, Light Scattering, Numericals.
15
02 Electro Chemistry Concentration cells: definition, Electrode Concentration Cell, electrolyte concentration cell, Concentration cell without transference, Concentration cell with transference, Liquid Junction potential, Elimination of liquid junction potential, Application of EMF measurement in determination of: Solubility of sparingly soluble salt, valency of metal ion, dissociation constant of weak acid, Transport number of ion, Ionic product of water, Degree of hydrolysis, pH by different electrodes.
15
03 A. Nuclear Chemistry Radioactivity, isotopes, isobars and isotones, Types of radiation, properties of radiation, detection and measurement of radioactivity, Types of radioactive decay, The group displacement law, radioactive degeneration series, rate of radioactive decay, Hazards of Radiation, applications of radio isotopes. B. Colloids Colloidal System, Lyophilic & Lyophobic sol, characteristics of Lyophilic & Lyophobic sol, preparation of sol, dispersion method, aggregation method, purification of sols, optical properties of sol, Tyndal effect, kinetic properties of sols, Brownian motion, electric properties of sols, Electrophoresis , Gold number, Application of Colloids.
15
Reference Books
Page 9 of 14
1. Physical Chemistry: G. M. Barrow, 5th Edition, McGraw-Hill education, India. 2. Principles of Physical Chemistry (44 Edition ) By Puri ,Sharma , Pathania 3. Advanced Physical Chemistry: Gurdeep Raj. 4. Principles of polymers Science by P.Bahadur and N.V.Sastry. (Second Edition ) 5. Polymer Science by V.R.Gowariker, N.V.Vashwanathan and Jaydev Shreedhar. 6. Polymer Science: Gowariker, Viswanathan and Sreedhar, 1st Edition (2012 reprint) New Age
International. 7. Essentials of Nuclear Chemistry: Arnikar, 4th Edition (2012 reprint), New Age International. 8. Physical Chemistry: Atkins, 9th Edition. Oxford University Press. 9. Advanced Physical chemistry: Gurtu and Gurtu, 11th Edition , Pragati Prakashan. 10. Physical chemistry: Levine, 6 th Edition, McGraw-Hill education, India. 11. ‘Essentials of Physical Chemistry’, B. S. Bahl, Arun Bahl and G. D. Tuli, S. Chand &
Company. 12. ‘Textbook of Physical chemistry ‘ P. L. Soni, O. P. Dharmaraha, U. N. Dash, Sultan 13. ‘A Textbook of Engineering Chemistry’ Shashi Chawla, Dhanpat rai & Co. 14. ‘Principles of Physical chemistry’ Puri, Sharama & Pathani, Vishal Publications 15. ‘Thermodynamics for chemist’ S. Glastone, East west Publications 16. ‘Physical Chemistry’ B. K. Sharma, Goel Publishing House
Practical Syllabus
Sr. No. Content
01 A. Applications of pH metry 1. To determine Molarity of strong / weak acid by titrating against 0.1 M NaOH solution. 2. The Dissociation Constant of weak monobasic acids like HAC, Formic acid, Benzoic acid by titrating against 0.1 M NaOH solution. 3. To determine Molarity of each acid present in a Mixture of strong acid and weak acid. B. Applications of Potentiometry 4. To determine Molarity of strong / weak acid by titrating against 0.1 M NaOH solution. 5. The Dissociation Constant of weak monobasic acids like HAC, Formic acid, Benzoic acid by titrating against 0.1 M NaOH solution. 6. To determine Molarity of each acid present in a Mixture of strong acid and weak acid. 7. To determine the concentration of Silver Nitrate solution by titrating against 0.1 M NaCl / KCl solution. 8. To determine Solubility and Solubility product of sparingly soluble salt AgCl. C. Applications of Conductometry 9. To determine Molarity of strong / weak acid by titrating against 0.1 M NaOH solution. 10. To determine Molarity of each acid present in a Mixture of strong acid and weak acid. 11. To determine the concentration of Silver Nitrate solution by titrating against 0.1 M NaCl / KCl solution. 12. To determine Cell Constant of a given conductivity cell and solubility and solubility product of sparingly soluble salt ( CaSO4 , PbSO4 )
Reference Books
1. Experimental physical chemistry by R. C. Das & B. Bahera 2. Practical in inorganic chemistry & analytical chemistry’, H.G. Raval, Nirav & Rupal Prakashan. 3. Advanced Practical Physical Chemistry by J.B.Yadav
Page 10 of 14
GANPAT UNIVERSITY
FACULTY OF SCIENCES
PROGRAMME B.Sc. Branch/Spec. Chemistry
SEMESTER VI Version 2.0.0.0
Effective From Academic Year 2020 Effective for the batch Admitted in July-2018
Subject Code BCHE6ACH Subject Name ANALYTICAL CHEMISTRY
Teaching Scheme Examination Scheme (Marks)
Per Week Lecture Practical
Total CE SEE Total L Tu P Tw
Credit 03 - 02 05 Theory 40 60 100
Hours 03 - 03 01 07 Practical 40 60 100
Pre-requisites
Before studying analytical chemistry, all students have basic knowledge of principles of spectroscopy NMR, FTIR, MASS and ESR.
Learning Outcome
After the successful completion of the course, students will be able to understand Basics of Spectroscopy and Analytical chemistry concepts. Principle, Instrumentation and applications of NMR and Mass spectroscopy. Principle, Instrumentation and applications of ESR spectroscopy Estimation of organic functional groups.
Theory Syllabus
Unit Content Hours
01
NMR spectroscopy: Introduction, principle and instrumentation, Number of signals, equivalent protons, Enantiomeric protons and diasteriomeric protons with appropriate illustrations, Chemical shift, Factors affecting chemical shift, Tau and Delta scales, shielding and deshielding protons, Intensity of signals-peak area and proton counting, Splitting of signals, spin-spin interactions and coupling constant, Deuterium labeling, Applications for aromaticity, H-bonding and conformation, Use of NMR spectroscopy and limitations of NMR spectroscopy, Problems for determination of structures of organic molecules. Introduction to 13C NMR, rules for 13C calculations, Extension to other nuclei (19F, 31P etc), Chemical shift reagents, Temperature dependent NMR and molecular dynamics
15
02 Mass spectroscopy: Introduction and principle of mass spectroscopy, working of mass spectrometer, various types of ions produced in mass spectrum, Interpretation of mass spectrum, Nitrogen rule, unsaturated site, mass spectrum of paraffin hydrocarbons, olefins, alcohols, aldehydes, carboxylic acids, amines, applications of mass spectroscopy, Interpretation of mass spectra, Mc-lafferty rearrangement
15
03 ESR Spectroscopy: Introduction, Principle, Instrumentation and Applications, Estimation techniques of functional groups and some important compounds, Estimation of organic functional groups with procedure, chemical reactions and necessary calculations: Aldehyde and Ketone , Carboxylic acid , Ester, Amide, Methoxy, Phenol and amine, Glucose, Aspirin, paracetamol
15
Reference Books
Page 11 of 14
1. Instrumental Methods of Chemical Analysis’, Chatwal Gurdeep R., Himalaya Pub. House 2. Instrumental methods of chemical analysis’, B. K. Sharma, Krishna prakashan Merut. 3. Principles of instrumental analysis’, Skoog. D. A., Thomason, Brooke/Cole 4. Quantitative analysis’, R.A. Day Jr. A.L. Underwood, 5th edition, Prentice Hall of India 5. Private Ltd., New Delhi. 6. Basic concept of Analytical Chemistry’, S. M. Khopkar, New Age International Publishers, New
Delhi. 7. Analytical Chemistry: An Introduction’, D.A. Skoog, D.M. West and F.J. Holler, 5th
Edition, Saunders college publishing. 8. Basic concept of Analytical Chemistry’, S. M. Khopkar, 9. Analytical Chemistry: An Introduction’, D. A. Skoog, D. M. West and F. J. Holler, 5th Edition 10. ‘Spectroscopy of Organic Compound’, P. S. Kalsi, New Age Publication 11. Organic spectroscopy by William Kemp Practical Syllabus
Sr. No. Content
01 Instrumentation and Calibration 1. Calibration, working, trouble shooting and Demonstration of UV Spectrophotometer 2. Calibration, working, trouble shooting and Demonstration of FTIR 3. Calibration, working, trouble shooting and Demonstration of HPLC
Chromatography [TLC] Analysis of the following drugs by Thin Layer Chromatography.
4. Aspirin 5. Paracetamol 6. Ibuprofen 7. Dyes 8. Amino acids
To determine the composition of a binary liquid mixture by Refractometry. (any two) To determine optical rotation of disaccharides by Polarimeter. (any two)
Reference Books
1. Comprehensive practical organic chemistry Preparation and qualitative analysis by V.K.Ahuwalia and Renu Aggarwal.
2. Qualitative Analysis by Vogel 3. Preparation and quantitative analysis by V.K.Ahuwalia and Renu Aggarwal. 4. Practical Chemistry By O.P.Pandey, D.N.Bajpai & S.Giri
5. An Advanced Course In Practical Chemistry By Ghoshal, Mahapatra & Nad
Page 12 of 14
GANPAT UNIVERSITY
FACULTY OF SCIENCES
PROGRAMME B.Sc. Branch/Spec. Chemistry
SEMESTER VI Version 2.0.0.0
Effective From Academic Year 2020 Effective for the batch Admitted in July-2018
Subject Code BELE6IDC Subject Name INDUSTRIAL CHEMISTRY
Teaching Scheme Examination Scheme (Marks)
Per Week Lecture Practical
Total CE SEE Total L Tu P Tw
Credit 02 - - 02 Theory 40 60 100
Hours 02 - - 02 - - - -
Pre-requisites
Before studying industrial chemistry, all students have basic knowledge of industrial organic compounds, paints, pigments, explosive and propellants.
Learning Outcome
After the successful completion of the course, students will be able to understand Basics of Organic and industrial chemistry concepts. Classification and applications of paints and pigments. To understand the concept and theory of Explosives and Propellants.
Theory Syllabus
Unit Content Hours
01
Paints & Pigments: A. Paints: Introduction, classification, distempers, constituent of paints, manufacturing of paints, setting of paints, requirements of good paints, Emulsion paint, constituent of emulsion paints, methods of manufacturing, Chemical action of emulsion paints, Latex, luminescent, fire retardant and heat resistant paints, Properties and manufacturing of Varnish. B. Pigments: Introduction, white pigments, white lead, manufacturing methods, Characteristics and uses of pigments.
15
02 Explosives and Propellants: A. Explosives: Introduction, Classification, Characteristics of explosive, Preparation and application of explosive, Oxygen balance, Blasting fuels, Rocket Propellants, Atom and Hydrogen bomb B. Propellants: Introduction, Classification, Characteristic and application of propellants
15
Reference Books
1. Industrial Chemistry by B.K. Sharma 2. Handbook of Industrial chemistry by Mohammad Farhat Ali 3. Introduction to Chemical Engineering Kinetics and Reactor Design, 2nd Edition by
Charles G. Hill, Thatcher W. Root 4. Homogeneous Catalysis: Mechanisms and Industrial Applications, 2nd Edition by Sumit
Bhaduri, Doble Mukesh 5. Advanced Organic Chemistry, Part A & B, F. A. Carey & R. J. Sundberg, Plenum Press. 6. A Text Book of Organic Chemistry, R. K. Bansal, New Age International (P) ltd. 7. Advanced Organic Chemistry, Jerry March. 8. Reaction Mechanism and Problems in Organic Chemistry, P. Chattopadhyay, Asian
Book Pvt Ltd, New Delhi. 9. Principles of Organic Synthesis, R.O.C Norman, J.M. Coxon, CRC Press.
Page 13 of 14
GANPAT UNIVERSITY
FACULTY OF SCIENCES
PROGRAMME B.Sc. Branch/Spec. Chemistry
SEMESTER VI Version 2.0.0.0
Effective From Academic Year 2020 Effective for the batch Admitted in July-2018
Subject Code BELE6MDC Subject Name MEDICINAL CHEMISTRY
Teaching Scheme Examination Scheme (Marks)
Per Week Lecture Practical
Total CE SEE Total L Tu P Tw
Credit 02 - - 02 Theory 40 60 100
Hours 02 - - 02 - - - -
Pre-requisites
Before studying drugs and intermediates, all students have basic knowledge of medicinal, structures, Pharmaceutical chemistry and basics of chemistry.
Learning Outcome
After the successful completion of the course, students will be able to understand Basics of organic and medicinal compounds concepts and theory. To understand concepts of ADME, QSAR, SAR, DDD, prodrug and chemotherapy. To create interest in students in learning medicinal chemistry and drug synthesis.
Theory Syllabus
Unit Content Hours
01
Terminology: Drugs, Pharmacophore, Pharmacodynamics, Pharmacokinetics (ADME, Receptors - brief treatment) Metabolites and Anti metabolites, agonists and antagonists, QSAR, prodrug, chemotherapy and chemotherapeutic index, LD50, drug discovery and design.
15
02 Drugs: Synthesis of the representative drugs of the following classes: analgesics agents, antipyretic agents, anti-inflammatory agents (Aspirin, paracetamol, lbuprofen); antibiotics (Chloramphenicol); antibacterial and antifungal agents (Sulphonamides; Sulphanethoxazol, Sulphacetamide, Trimethoprim); antiviral agents (Acyclovir), Central Nervous System agents (Phenobarbital, Diazepam), Cardiovascular (Glyceryl trinitrate), antilaprosy (Dapsone), HIV-AIDS related drugs (AZT- Zidovudine).
15
Reference Books
1. Principles of Medicinal Chemistry, Vol. I & II (5/e), by S. S. Kadam, K. R. Mahadik, K. G. Bothra Nirali Prakashan
2. Burger’s medicinal chemistry and drug design (5/e) 1997, vol 1 to 5 edited by Manfred E.Woltt John wiley and sons Mc. New york
3. Principles of medicinal chemistry by William A. Foye 4. Medicinal Chemistry by Ashutosh kar(Ed. 6th ) New Age International 5. The organic chemistry of drug synthesis vol I, II and III (1980) ed by D. lednicer and L.A. mitscher
Johyn wiley and sons, New york 6. Text book of organic medicinal and pharmaceutical chemistry, Wilson and Gisvold Toppan co.Ltd, 7. The pharmaceutical basis of theraperutics by Geoman and Gilman 8. Medicinal Chemistry, A. Burger Vols. I to V Ed. M. E. Wolff, John Wiley. 9. Pharmacological Basis of Therapeutics, McGraw-HilI, Goodman & Gilman. 10. Introduction to Drug Design,New Age International. S. S. Pandeya& J. R. Dimmock. 11. Strategies for Organic Drug Synthesis and Design,John Wiley, D. Lednicer. 12. Introduction to Medicinal Chemistry (3rd edn.), Graham & Patrick. 13. Medicinal Chemistry - A molecular and Biochemical Approach,Thomas Nogrady and Donald
F.Weaver
Page 14 of 14
GANPAT UNIVERSITY
FACULTY OF SCIENCES
PROGRAMME B.Sc. Branch/Spec. Chemistry
SEMESTER VI Version 2.0.0.0
Effective From Academic Year 2020 Effective for the batch Admitted in July-2018
Subject Code BELE6BCH Subject Name BIO-CHEMISTRY
Teaching Scheme Examination Scheme (Marks)
Per Week Lecture Practical
Total CE SEE Total L Tu P Tw
Credit 02 - - 02 Theory 40 60 100
Hours 02 - - 02 - - - -
Pre-requisites
Before studying biochemistry chemistry, all students have basic knowledge of bio-organic compounds, amino acids, proteins, fatty acids, nucleic acid and lipids.
Learning Outcome
After the successful completion of the course, students will be able to understand Basics of Bio-Organic, Bio-chemistry concepts. To understand concept of Enzyme synthesis, DNA, RNA, Electrophoresis Nucleoproteins and
nucleic acids. To create interest in students in Nucleic acid, lipid and fatty acids theory and classification.
Theory Syllabus
Unit Content Hours
01
Amino Acids and Proteins Proteins, Structure of amino acids, Amino acids as dipolar ions, Isoelectric point of amino acids, Configuration of natural amino acids, Preparation of amino acids, Peptides. Geometry of the peptide linkage, Determination of structure of peptide. Terminal residue analysis. Partial hydrolysis. Synthesis of peptides, Proteins. Classification and function. Denaturation, Structure of proteins, Secondary structure of protein, Peptide chain, Side chain. Isoelectric point. Electrophoresis, Conjugated proteins. Prosthetic group. Nucleoproteins and nucleic acids
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02 A. Enzymes Introduction, types, classification and functions of Enzymes, Coenzymes. Mechanism of enzyme action of Chymotrypsim. B. Lipid and Fatty acids Introduction to lipid, occurrence, properties, classification of lipid. Importance of phospholipids, sphingolipid and glycerolipid. Biological function of lipid. Fatty acid, - Introduction, Nomenclature and classification of fatty acid Essential and non-essential fatty acids.
15
Reference Books
1. Biochemistry by U. Satyanarayana Elsevier 2. Biochemistry by Lubest Stryer · 3. Fundamental of Biochemistry : A.C. Deb 4. Textbook of Biochemistry by Jain & Jain 5. Principles of biochemistry , A.L., Lehninger. 6. Outlines of biochemistry (1976) Wiley Eastern, E.E. conn and p.k. stumpf. 7. BIOCHEMISTRY (1995) L. Stryer 8. Biochemistry, 3rd Edition, John Wiley & Sons, Voet, D. and Voet, J.G.
