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CARDIAC IMAGING
Dr. Rahmad Mulyadi, SpRadRadiology Department
University of IndonesiaJakarta
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Atrium - Top two chambers
Right Atria - receive blood from body
Left Atria receive blood from lungs
Ventricles - Bottom two
chambers
Right ventricle pumps blood to lungs to
pick up oxygen
Left ventricle pumps blood to the rest of
the body
Anatomy of the Human Heart
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Coronary Arteries
Cells within the heart need
oxygen
Two CAs carry oxygen-rich blood
to heart muscle
Right Coronary artery
Left Main branches into two
narrower arteriesLeft Circumflex
Left Anterior Descending
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Diagnostic Studies
Invasive
Cardiac catheterization
Non Invasive
Chest X ray Echocardiography
Doppler Ultrasonography
Computed Tomography (CT) Magnetic Resonance Imaging (MRI)
Nuclear Medicine.
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Chest X-RayAnalysis of chest film for cardiac disease : Cardiac enlargement : shape and size
Overall : Cardiothoracic ratio (CTR) > 50% Selective chamber enlargement Pericardial effusions
Secondary/associated pulmonary changes
The mediastinum, for the size and location of the aortaand major systemic veins
Great vessels changes calcify, elongation, aneurysm
Position of pacemaker
Extracardial anomalies that may be associated with heartdiseaseThe plain film is virtually never relied upon for the diagnosisof the nature if the cardiac lesion it is valuable as anindicator of the severity of any haemodynamic disorder in
revealing cardiomegaly, state of the lungs, and to followprogress.
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Computed Tomography
Computed tomography is a digitally based x-ray
technique the resulting images arise fromdifferential x-ray absorption of tissue, a feature thatrests primarily on atomic weight (and thus theelectron density) of the various tissues.
The technique uses a narrowly collimatedx-raybeam to irradiate a slice of the body the amountof radiation transmitted is collected by photo-multiplier tubes and counted digitally.
By rapidly acquiring views from numerous different
projections, achieved by quickly rotating the tubeand detectors around the body.
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Once these transmission values are collected,they can be digitally filtered and back-projectedmathematically (by a technique known as
Fourier transformation) onto a matrix whichrepresents fine differentiation of tissue densities The Hounsfield scale (bone is +1000 and airis -1000) ,
CT : single slice/ multislices (MSCT), can bedisplayed as a 3-dimensional structure. MSCT : native/contrast CT,CT angiography,
perfusion CT. Computed tomography has the advantage of
rapid acquisition of images, but employs ionizingx-ray radiation which must be usedconservatively to avoid harmful cumulativebiologic effect.
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Noninvasive Diagnostic Studies
Echocardiography
Echocardiography has great value in
assessing congenital cardiac anomalies
and should usually be the first advanced
diagnostic study to be carried out if the
history, the physical examination, the
chest X ray, and the electrocardiogramsuggest the presence of congenital heart
disease.
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Noninvasive Diagnostic Studies
Echocardiography
The standard M-mode display and the
two-dimensional display provide such
information about cardiac anatomy as the
size of the cardiac chambers, the
connections of the great vessels,
abnormalities of the valves, andsubvalvular obstructions.
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Noninvasive Diagnostic Studies
Doppler ultrasonography
Doppler ultrasonography is useful indetecting septal defects and directly
assessing the amount of blood thatshunts through the defect.
The size of the shunt through a septaldefect can also be estimated from
Doppler ultrasound studies by comparingthe velocity of the blood flow through theaorta with velocity through the pulmonaryartery.
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Magnetic Resonance Imaging (MRI)
Magnetic resonance imaging depends on immersing thebody in a steady, strong magnetic field, commonly up to1.5 Tesla (i.e. 15,000 Gauss for reference, the earth'smagnetic field is about 0.5 Gauss).
Some modern "whole-body" machines now operate at 4or more Tesla.
Hydrogen atoms, pervasive in the water which makes upabout 70% of the body's mass, have a dipole propertyby virtue of their characteristic spins.
Hydrogen spinning atoms, influenced by thepermeating magnetic field precess in alignment withthe dominant magnetic field Subjecting the bodytissues to an additional magnetic field gradient aspecific tissue slice of the body for imaging whileabsorbing this radiation in a resonant fashion.
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Hydrogen atoms alter their net magnetic axis directiontemporarily (excitation state) _rapidly decays to alower energy state while emitting its own unique radiofrequency signal detected by an external radio-frequency coil calculating images tissue-relatedimages.
Special pulse-echo sequences permit high level signals tobe detected from flowing blood images of thevasculature and it's blood velocity characteristics.
Functional MRI" detect differences oxygen-saturatedand de-saturated blood.
Brain processes of "thought" such as vision, motorcontrol and speech can be detected (though at lowspatial resolution) by virtue of their local oxygen
consumption when activated.
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To evaluate :
Cardiac structure Cardiac chamber
Valvular heart diseases
Pericardial diseases
Congenital heart diesases
Functional imaging in ischemic heart disease
Magnetic Resonance Coronary Arteriography coronary artery.
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Chest x ray
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Features that are typically examined on a chest X-ray
Every doctor will have a different approach to examining chest X-rays. A
commonly used mnemonic for what to look for on a chest X-ray is: It May Prove
Quite Right (but) Stop And Be Certain How Lungs Appear:
I = Identification (name, age, sex, indication for X-ray) by mas
M = Markers (differentiate left from right - diagnose dextrocardia)
P = Position - the spinous process ofT4 should be between the heads of the clavicle (if it isn't thebody is rotated)
Q = Quality - is the film penetrated properly. In a properly penetrated film the vertebral interspacesshould be visible behind the central (cardiac) shadow
R = Respiration - chest X-rays are typically done with full inspiration
(but) S = Soft tissue - look forsubcutaneous emphysema (suggestive of trauma), soft tissue swelling
A = Abdomen - look forfree abdominal air(suggests penetrating trauma, peritonitis, or recentsurgery)
B = Bone - look for fractures (these tend to be at the lateral aspects because of the mechanics -bending moment largest at lateral aspect)
C = Central shadow (cardiac silhouette) - greater than 50% of lateral distance in frontal view at thediaphragm suggests cardiac enlargement (usually secondary to heart failure) or a pericardialeffusion). A widened mediastinum may suggest aortic dissection.
H = Hila (of the lungs) - can be affected in lung disease, malignant processes and infection (hilarlymphadenopathy).
L = Lungs - for consolidation, interstitial lung disease (reticular, nodular or reticulonodular),honeycombing, miliary pattern, granulomas, lung masses
A = Absent structures/Apices of the lung (forpneumothorax
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Another approach is to examine first any major abnormality,
and then "review areas":
the apices,
the hila,
behind the heart (it must be rememberedthat lung can be seen through the heart),
the cardiophrenic angles,
the costophrenic angles,
beneath the diaphragm, and then
bone and soft tissues.
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Views
Typical views
PA (posterior-anterior) view - The patient faces away from X-ray source - X-rays pass from their source to patients back through the body to exit throughthe anterior body wall to expose the film
AP (anterior-posterior) view - The patient faces the X-ray source - these aretypically done in the ICU
Lateral view
The most common view is the PA (posterior-anterior) and is frequently donewith a left lateral view (so one can identify the location of abnormalities in 3-D space). PA views are preferred to AP views (which are often done withmobile/portable X-ray equipment), but much less convenient in the ICUsetting or when a patient cannot otherwise leave their bed. PA views arepreferred because the central shadow is better defined, the magnification ofthe heart is reduced, radiation to the breast tissue is reduced, and less ofthe lungs obscured by the heart/pericardial sac.
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Additional views
DecubitusDecubitus - useful for differentiating pleuraleffusions from consolidation (e.g. pneumonia)andLoculated effusions from free fluid in the pleura. if thethickness of linear fluid exeeds 1cm its mondatory to
pleural tap must be done "Tapping pluid"(N.A.Exeer,MD).In effusions, the fluid layers out(by comparison to an up-right view, when it often accumulates in the costophrenicangles).
Lordotic view - used to visualize the apex of the lung, to
pick-up abnormalities such as a Pancoast tumour. Expiratory view - helpful for the diagnosis of
pneumothorax
Oblique view Lordotic
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Lateral viewThe cardiacsilhouette in this view isoval in shape and occupythe anterior half of thethoracic cage.
The ascending aorta andright ventricle form theanterior border, while theleft atrium and leftventricle form the
posterior border.
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The frontal film
Trachea
R main
bronchus
L main
bronchus
Pulmonary artery
Gastric air bubble
Blood-filled
pulmonary vesselscast soft gray
shadow and
typically taper out to
periphery, while
bronchi and
bronchioles are air
filled and do not cast
a shadow on the
image
Pleura not normally
visible
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Ascending
aorta
Aortic knob
Descending
aorta
RALA
RV
LV
The frontal chest film
may be acquired PA
or AP
View the film as
though the patient is
facing you with hisleft on your right
If the film is
unmarked, rememberyour anatomy (heart
and aortic arch are
left of midline)
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The diaphragm is a
musculotendinous
sheet separating the
thoracic and
abdominal cavities
The left and right
hemidiaphragms
are usually well
seen on PA and
lateral films
The plane of the right
diaphragmatic dome is
usually about half an
interspace higher than
the left
R
L
L
R
Look at the diaphragm and upper abdomen
~ interspace
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typically left chest is placed
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Normal lateral film
E
T
DA
typically left chest is placed
against detector to minimize
cardiac magnification
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Barium Swallow/ Cor analisa
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Normal Chest X-ray
Cardiac Structures
Position
More central in younger infants and children
More on the L side in older infants and teens
Size
In AP view if < 2 years take up to ~ 65%
If > 2 years - ~ 50%
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Mitral Stenosis (MS)
Definition :
Obstruction to left ventricular blood inflow atthe level of the mitral valve (MV)
Mit l t i
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Mitral stenosis
Mitral stenosis is a heart valvedisorder that narrows orobstructs the mitral valveopening. Narrowing of themitral valve prevents the valvefrom opening properly and
obstructs the blood flow fromthe left atrium to the leftventricle. This can reduce theamount of blood that flowsforward to the body. The mainrisk factor for mitral stenosis isa history of rheumatic fever but
it may also be triggered bypregnancy or other stress onthe body such as a respiratoryinfection, endocarditis, andother cardiac disorders
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Mitral Stenosis
Tests may include: Chest x-raya test that uses radiation to take pictures of structures inside
the chest
Electrocardiogram (ECG, EKG)a test that records the heart's activity bymeasuring electrical currents through the heart muscle
Echocardiograma test that uses high-frequency sound waves
(ultrasound) to examine the size, shape, and motion of the heart; in this test,the sound waves are passed through a transducer that is placed onto yourchest.
Transesophageal echocardiogramuses the same ultrasound techniquesto create an image of your heart, but gives a more detailed image. In thistest, the transducer is passed down your esophagus (the tube in your throatthat runs from your mouth into your stomach), to allow a better examination
of the mitral valve. Cardiac catheterizationan x-ray of the heart's circulation that is done after
injection of a contrast dye
Holter monitora portable EKG device that you wear for 24 or more hours,to detect heart rhythm abnormalities that often accompany mitral stenosis
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Mitral Stenosis
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Mit l St i l b bl d
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Mitral Stenosis - upper lobe blood
diversion. Trivial enlargement of the
transverse diameter of theheart. Left atrium causesdouble outline (opposite rightarrow) and is somewhatdilated. Left atrial appendageis dilated, causing aprominence of the left border(opposit left arrow). Upper lobevessels larger than lower lobevessels, that is, upper lobe
blood diversion. An arrowpoints to a dilated upper lobevein.
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MS
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MS
Mitral Regurgutation
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Mitral Regurgutation
(MR)/ Mitral Insufficiency (MI)
Definition:
Incomplete closure of mitral valve during left
ventricular systole leading to retrograde
blood flow into left atrium.
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Mitral regurgitation
Acute mitral regurgitation Chronic mitral regurgitation
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Mitral Regurgitation
Chest X-ray
Heart size may be normal in mild cases or
in acute regurgitation
Cardiomegaly (due to left atrial and left
ventricular enlargement in significant
chronic mitral regurgitation
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MI
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The echocardiogram is commonly used toconfirm the diagnosis of mitral regurgitation.Color doppler flow on the transthoracicechocardiogram (TTE) will reveal a jet ofblood flowing from the left ventricle into the
left atrium during ventricularsystole. Because of the inability in getting accurate
images of the left atrium and the pulmonaryveins on the transthoracic echocardiogram,a transesophageal echocardiogram may benecessary to determine the severity of themitral regurgitation in some cases.
Factors that suggest severe mitralregurgitation on echocardiography includesystolic reversal of flow in the pulmonaryveins and filling of the entire left atrial cavityby the regurgitant jet of MR.
Transesophageal echocardiogram of
mitral valve prolapse
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The Role of Imaging in Detection
Congenital Heart Disease
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For the fetus the placenta is the
oxygenator so the lungs do little
work
Shunts are necessary for survival
- Ductus venosus (by passes liver)
- Foramen ovale (RL atrial level shunt
- Ductus arteriosus (RL arterial
level shunt
With first few breaths lungs expand
and serve as the oxygenator (and
the placenta is removed from thecircuit)
Foramen ovale functionally closes
Ductus arteriosus usually closes
within first 1-2 days
Fetal Circulation
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Cardiac Position: Dextrocardia
Situs inversus Situs solitus
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Chest X-ray examination
Cardiac Size
To examine size and
shape of the cardiac
To examine the
enlargement of each
cardiac chamber
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Chest X-ray examination
Rule-out pulmonaryparenchymal disease
Evaluate pulmonary
blood flow
increased versus
decreased blood flow
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Noninvasive Diagnostic Studies
Computed tomography (CT)
CT provides a good display of the
anatomic abnormalities associated with
congenital heart disease and offers
advantages over echocardiography in
demonstrating anomalies involving the
great vessels.
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Indications: Cardiac CT
Detection of disease or pathology
i.e., diagnosis
Improve clinical decision making(Not first imaging)
No role in defining normal anatomy
No role in assessing function
Not a screening tool
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Mitral Regurgitation
Chest X-ray
Heart size may be normal in mild cases or
in acute regurgitation
Cardiomegaly (due to left atrial and left
ventricular enlargement in significant
chronic mitral regurgitation
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Other Indications
Extracardiac great vessel anomalies
Intracardiac shunt lesions
Diagnosis of cardiac congenital diseases
atrial septal defects
ventricular septal defects
Evaluate post-operative anatomyusually complex cyanotic heart disease
Pulmonary Sling:
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y gLeft pulmonary artery arises from right
pulmonary artery
Neonate
A ti C t ti
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Aortic Coarctation
10-day old girl with CHF; 8 cc contrast,
3D CTCT
Patent Ductus Arteriosus
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Patent Ductus Arteriosus
CT MR
In patent ductus arteriosus, pulmonary blood flow, LA and
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p , p y ,
LV volumes, and ascending AO volume are increased
AO = Aorta
LA = Left aorta
LV = Left Ventricle
PA = Pulmonary artery
Shunt Lesion: Septal Defects
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Shunt Lesion: Septal Defects
Post ASD repairASD/VSD
ASD
Post operative Evaluation:
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Post-operative Evaluation:
Graft right atrium
to pulmonary arteryGrafts subclavian arteries to
pulmonary arteries
N i i Di ti St di
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Noninvasive Diagnostic Studies
Magnetic resonance imaging (MRI)
MRI provides information similar to
that provided by CT. MRI offers better resolution than CT
without the disadvantages of the
radiopaquecontrast medium used inthat technique.
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I i Di ti St di
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Invasive Diagnostic Studies
Cardiac catheterization andselective angiocardiography
are the most definitive diagnostic
techniques currently available foruse in congenital heart disease.
Noninvasive studies often provide
information that is equivalent to that
obtained from cardiac catheterization and
is sufficient for planning surgical
treatment.
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Congenital Heart Disease (CHD)
Simple way to classify is:
Acyanotic CHD (LR shunts)
Cyanotic CHD (RL shunts) Obstructive lesions
CLASSIFICATION OF CHD
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CLASSIFICATION OF CHD
L - R SHUNTS INCLUDE :
ASD 7.5% of CHD
VSD COMMONEST CHD 25%
PDA 7.5% of CHD
CLASSIFICATION OF CHD
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CLASSIFICATION OF CHD
R L SHUNTS
Defect between R and L heart
Resistance to pulmonary blood flow PBF
hypoxemia and cyanosis
INCLUDE :
TOF 10% of CHD, commonest R-L shunt
PULMONARY ATRESIA TRICUSPID ATRESIA
Ob t ti L i
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OBSTRUCTIVE LESIONS INCLUDE :
AORTIC STENOSIS
MITRAL STENOSIS
PULMONIC STENOSIS
COARCTATION OF AORTA 8% of CHD
80% have bicuspid aortic valve
Obstructive Lesions
ASD
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ASD
AP view The pressure in the left atrium is higher than the
right atrium. therefore, a defect in the atrialseptum will result in left to right shunting of
blood. The increased blood volume flowingthrough the right heart and pulmonaryvasculature will cause prominant pulmonaryvascular markings on chest X-Ray, and in
moderate to severe cases there will also becardiomegaly due to right atrial enlargementcausing prominance of the right heart border.
ASD
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ASD
Lateral View Prominant pulmonary vasculature is noted,
particularly in the hilar region. In severe
cases the right ventricle is dilated, this willbe manifested by fullness of the anteriorborder of the heart in the lateral viewsresulting in obliteration of lung tissue
normally noted in between the heart andsternum.
ASD
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ASD
PA VIEW
ASD
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ASD
Lateral View Prominant pulmonary
vasculature is noted,particularly in the hilarregion. In severe cases
the right ventricle isdilated, this will bemanifested by fullness ofthe anterior border of theheart in the lateral viewsresulting in obliteration oflung tissue normallynoted in between theheart and sternum.
Atrial Septal Defect
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Atrial Septal Defect
Hole between the twoatria
Blood flows left to right
PFO Patent foramen
ovale fails to close
Right atrium and ventricle
becomes dilated
Too much blood to the
lungs
Patofisiologi
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Patofisiologi
Atrial Septal Defect
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Atrial Septal Defect
ASD with Eisenmenger syndrome
Chest X ray
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Chest X-ray
The pulmonary vascular markings increasedThe main pulmonary artery segment dilated
Cardiac enlargement (RV,RA)
Diameter of ascending aorta is small to normal
ASD
Ventricular Septal Defect
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Ventricular Septal Defect
Hole between the twoventricles
Left to right shunt majority
Dilated right ventricle too much blood tolungs increase inpulmonary pressure
Smaller defects canclose spontaneously
VSD
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VSD
VSD
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VSD
AP view The pressure in the left ventricle is higher than the right
during systole. This will result in left to right shuntingacross the VSD, throughout systole. The increasedpulmonary blood flow will cause prominent pulmonary
vasculature. The right ventricle will become hypertrophied with
moderate to large amount of shunt leading tocardiomegaly.
The left atrium will become dilated due to increase
pulmonary venous blood return. In the AP view, this willbe manifested by widening of the carinal angle since theleft atrium is situated just below the right and left mainbronchi as they bifurcate.
VSD
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VSD
PA VIEW
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Lateral view
This view best demonstrates the left atrial
dilatation. The dilated left atrium will cause
the esophagus to dilate, as noted in thisfigure with Barium swallow.
VSD
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VSD
LATERAL VIEW BARIUM SWALOW
Ventricular Septal Defect
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Ventricular Septal Defect
RA
RV
LA
LV
PicsofVSD
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Pics of VSD
PicsofVSD
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Pics of VSD
PicsofVSD
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Pics of VSD
PDA patent ductus arteriosus
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PDA patent ductus arteriosus
Connection LeftPulmonary Artery to
Aorta
PDA Problem : Too much blood goingto lungs
Increased PA pressure
Increase RV Long term damage to
lungs and birth
PDA patent ductus arteriosus
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PDA patent ductus arteriosus
RA
RV
LA
LV
RA
RV
LA
LV
AcuteChronic
PDA patent ductus arteriosus
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PDA patent ductus arteriosus
Tetralogy of Fallot (TOF)
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ventricular septal defect,
that allows blood to passfrom the right ventricle tothe left ventricle withoutgoing through the lungs
a narrowing (stenosis) ator just beneath the
pulmonary valve thatpartially blocks the flow ofblood from the right side ofthe heart to the lungs
the right ventricle is moremuscular than normal
(RVH)
the aorta lies directly overthe ventricular septaldefect (over-riding aorta)
Tetralogy of Fallot (TOF)
Tetralogi
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Fallot
VSD Aorta di atas VSD
Obstruksi aliran
ventrikel kanan
Hipertrofi ventrik.Kanan
Cyanotic congenital
heart disease
Tetralogy of Fallot (TOF)
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Tetralogy of Fallot (TOF)
RA
RV
LA
LV
Tetralogy of Fallot
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Tetralogy of Fallot
Boot
shape
RVH liftingapex
loss of PA
knob
Conclusion
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Conclusion
Non Invasive imaging test is an evolvingand promising modality but its application
needs to validated with rigorous clinical
investigations. Ultimately, appropriate selection of a
noninvasive imaging test for a given
patient should be evidence-based.