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CHAPTER 8: BLOOD PRESSURE CONTROL AND DYSLIPIDAEMIA

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CHAPTER 8: BLOOD PRESSURE CONTROL AND DYSLIPIDAEMIA. S. Prasad Menon Hooi Lai Seong Lee Wan Tin Sunita Bavanandan. Source: 20 th MDTR Report 2012, NRR. Table 8.1.1: Distribution of pre dialysis systolic blood pressure, HD patients 1997-2012. Source: 20 th MDTR Report 2012, NRR. - PowerPoint PPT Presentation
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CHAPTER 8: BLOOD PRESSURE CONTROL AND DYSLIPIDAEMIA S. Prasad Menon Hooi Lai Seong Lee Wan Tin Sunita Bavanandan Source: 20 th MDTR Report 2012, NRR
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Page 1: CHAPTER 8: BLOOD PRESSURE CONTROL AND DYSLIPIDAEMIA

CHAPTER 8: BLOOD PRESSURE CONTROL AND

DYSLIPIDAEMIA

S. Prasad MenonHooi Lai Seong

Lee Wan TinSunita Bavanandan

Source: 20th MDTR Report 2012, NRR

Page 2: CHAPTER 8: BLOOD PRESSURE CONTROL AND DYSLIPIDAEMIA

Table 8.1.1: Distribution of pre dialysis systolic blood pressure, HD patients 1997-2012

YearNumber

of patients

Mean SD Median LQ UQ

% Patients pre dialysis systolic blood pressure (mmHg)

<120 120-<140 140-<160 160-<180 ≥180

1997 1659 144.5 20.8 144.2 130.8 158.1 11 30 35 19 41998 2108 146 20.5 146.7 133.2 159.2 10 27 39 19 51999 2965 148.7 20.8 148.5 135.3 162.2 8 25 38 23 62000 4308 148 20.6 147.8 134.7 161.7 9 25 38 23 62001 5147 148.8 20.9 148.8 134.9 162.6 8 25 37 23 72002 5911 149.2 20.6 149 135.8 163.3 8 24 38 24 62003 6834 149.7 20.2 149.8 136.4 162.9 7 24 39 23 72004 7937 149.7 20 150 136.6 163.1 7 23 39 25 62005 9221 149.9 19.4 149.6 137 162.8 6 24 40 24 62006 11526 151.4 19.3 151.1 138.8 164 5 22 41 25 72007 12830 152.1 19.1 151.9 139.3 164.7 5 21 40 27 72008 15314 152.1 19 152 139.4 164.6 4 21 40 27 72009 17871 151 19 150.6 138.2 163.5 5 23 41 25 72010 19432 150.8 18.9 150.4 138.3 163.3 5 23 41 25 62011 22685 151.5 18.8 151.4 139 163.9 4 22 41 26 62012 25812 151.5 18.9 151.3 139.1 163.8 5 22 41 25 7

Source: 20th MDTR Report 2012, NRR

Page 3: CHAPTER 8: BLOOD PRESSURE CONTROL AND DYSLIPIDAEMIA

Figure 8.1.1(a): Cumulative distribution of pre dialysis systolic blood pressure, HD patients 1997-2012

Source: 20th MDTR Report 2012, NRR

0

.25

.5

.75

1

Cum

ulat

ive

dist

ribu

tion

110 120 130 140 150 160 170 180 190Pre dialysis Systolic Blood Pressure (mmHg)

1997 2000 20042008 2012

Page 4: CHAPTER 8: BLOOD PRESSURE CONTROL AND DYSLIPIDAEMIA

Figure 8.1.1(b): Mean of pre dialysis systolic blood pressure, HD patients 1997-2012

0

20

40

60

80

100

120

140

160N

o. o

f pa

tien

ts

'97 '98 '99 '00 '01 '02 '03 '04 '05 '06 '07 '08 '09 '10 '11 '12Year

Mean of pre dialysis systolic blood pressure 1997-2012

Mean of pre dialysis SBP, HD patients

Source: 20th MDTR Report 2012, NRR

Page 5: CHAPTER 8: BLOOD PRESSURE CONTROL AND DYSLIPIDAEMIA

Table 8.1.2: Distribution of pre dialysis systolic blood pressure, PD patients 1997-2012

YearNumber

of patients

Mean SD Median LQ UQ

% Patients pre dialysis systolic blood pressure (mmHg)

<120 120-<140 140-<160 160-<180 ≥180

1997 468 142.7 20.3 142.9 128.3 156.3 13 31 37 17 31998 519 141 21.2 140 126.4 157.5 16 34 29 18 31999 576 141 19.8 140 127.2 156 14 35 34 15 22000 638 137.2 20.4 136.1 123.3 150 18 39 29 13 22001 739 139 20.2 137.5 125.8 151.7 16 38 30 13 32002 843 139.8 20.5 140 127.1 151.8 14 36 34 12 42003 1154 140.5 20.1 140 126.7 154.1 15 35 32 15 32004 1259 141 19.8 140.9 127.4 154.5 13 34 36 14 32005 1351 140.4 20.2 139.3 127.3 153.2 13 38 32 14 32006 1523 139.3 19.3 138.4 126.7 151.6 14 40 32 11 22007 1753 139.9 19.2 139.4 127 152.8 15 37 33 13 22008 2049 139.4 18.7 139.5 126.7 151.4 15 36 35 12 22009 2177 140.7 18.7 140.5 128.1 153.4 13 35 35 14 22010 2327 140 17.8 140 128.3 151.4 12 37 38 11 22011 2578 139.7 18 140 127.9 151.5 13 36 38 11 22012 2796 140.8 18.3 141.1 128.5 152.8 13 34 38 14 2

Source: 20th MDTR Report 2012, NRR

Page 6: CHAPTER 8: BLOOD PRESSURE CONTROL AND DYSLIPIDAEMIA

Figure 8.1.2 (a): Distribution of pre dialysis systolic blood pressure, PD patients 1997-2012

Source: 20th MDTR Report 2012, NRR

0

.25

.5

.75

1

Cum

ulat

ive

dist

ribu

tion

100 110 120 130 140 150 160 170 180Pre dialysis Systolic Blood Pressure (mmHg)

1997 2000 20042008 2012

Page 7: CHAPTER 8: BLOOD PRESSURE CONTROL AND DYSLIPIDAEMIA

Figure 8.1.2(b): Mean of pre dialysis systolic blood pressure, PD patients 1997-2012

0

20

40

60

80

100

120

140

No.

of p

atie

nts

'97 '98 '99 '00 '01 '02 '03 '04 '05 '06 '07 '08 '09 '10 '11 '12Year

Mean of pre dialysis systolic blood pressure 1997-2012

Mean of pre dialysis SBP, PD patients

Source: 20th MDTR Report 2012, NRR

Page 8: CHAPTER 8: BLOOD PRESSURE CONTROL AND DYSLIPIDAEMIA

Table 8.1.3: Distribution of pre dialysis diastolic blood pressure, HD patients 1997-2012

YearNumber

of patients

Mean SD Median LQ UQ

% Patients pre dialysis diastolic blood pressure (mmHg)

<70 70-<80 80-<90 90-<100 ≥100

1997 1660 83.7 10.9 84.2 77 90.7 10 23 38 22 61998 2108 83.5 10.7 83.9 76.9 90.6 10 24 38 23 51999 2965 83.5 10.5 83.5 77.1 90 10 24 40 21 62000 4307 82.2 10.4 82.3 75.7 89 11 28 39 18 42001 5146 81.6 10.4 81.7 75 88.3 12 30 37 17 42002 5907 81.2 10.4 81.3 74.5 88.1 13 30 37 16 32003 6832 80.6 10.2 80.8 73.9 87.2 14 32 37 14 32004 7935 80.3 10.2 80.3 73.6 86.9 15 33 36 14 32005 9221 80.3 10.6 80.4 73.5 87 15 32 36 14 32006 11525 80.4 11.1 80.4 73.3 87.1 16 32 35 14 32007 12830 80.4 11.1 80.2 73.1 87 16 32 34 14 42008 15312 79.8 11.1 79.6 72.4 86.7 18 33 33 13 32009 17870 79.7 12 79.2 72 86.4 19 33 31 12 42010 19430 79.4 11.8 79 71.8 86.2 20 34 31 12 42011 22684 79.3 11.9 78.9 71.7 86.2 20 34 31 12 42012 25809 78.9 11.8 78.6 71.2 85.8 21 34 30 11 4

Source: 20th MDTR Report 2012, NRR

Page 9: CHAPTER 8: BLOOD PRESSURE CONTROL AND DYSLIPIDAEMIA

Figure 8.1.3 (a): Cumulative Distribution of pre dialysis diastolic blood pressure, HD patients 1997-2012

Source: 20th MDTR Report 2012, NRR

0

.25

.5

.75

1

Cum

ulat

ive

dist

ribu

tion

60 65 70 75 80 85 90 95 100Pre dialysis Diastolic Blood Pressure (mmHg)

1997 2000 20042008 2012

Page 10: CHAPTER 8: BLOOD PRESSURE CONTROL AND DYSLIPIDAEMIA

Figure 8.1.3(b): Mean of pre dialysis diastolic blood pressure, HD patients 1997-2012

0

10

20

30

40

50

60

70

80

No.

of p

atie

nts

'97 '98 '99 '00 '01 '02 '03 '04 '05 '06 '07 '08 '09 '10 '11 '12Year

Mean of pre dialysis diastolic blood pressure 1997-2012

Mean of pre dialysis DBP, HD patients

Source: 20th MDTR Report 2012, NRR

Page 11: CHAPTER 8: BLOOD PRESSURE CONTROL AND DYSLIPIDAEMIA

Table 8.1.4: Distribution of pre dialysis diastolic blood pressure, PD patients 1997-2012

YearNumber

of patients

Mean SD Median LQ UQ

% Patients pre dialysis diastolic blood pressure (mmHg)

<70 70-<80 80-<90 90-<100 ≥100

1997 467 85.3 10.6 85.8 79.8 91.4 6 19 41 26 81998 519 84.3 11.3 85 77.1 90.1 8 24 36 24 81999 576 84 10.9 84.2 77.9 90 9 20 44 20 72000 638 82.9 11 83.3 76.6 89.6 10 24 41 20 52001 739 83.1 10.9 82.7 76.4 89.6 9 29 38 18 62002 843 82.8 10.8 83.4 76.1 90 11 24 41 21 52003 1156 82.2 10.9 82.3 75.6 89.4 12 26 38 19 42004 1258 82.2 10.5 83 75.4 89.2 11 28 38 18 42005 1351 81.6 10.9 82.2 75 88.3 12 29 40 15 52006 1522 81.3 10.6 81.5 74.8 88 13 28 40 15 32007 1752 80.6 10.7 80.7 74 86.9 14 32 38 12 32008 2049 79.7 10.1 80 73 86.3 16 32 36 13 22009 2177 80.2 10.3 80.2 73.5 86.9 15 33 35 14 32010 2327 79.9 10.4 80 72.9 86.8 17 33 34 13 32011 2578 80 10.2 80.1 73.3 86.7 16 33 36 13 22012 2799 81.2 12.1 80.8 73.9 87.8 15 31 35 15 4

Source: 20th MDTR Report 2012, NRR

Page 12: CHAPTER 8: BLOOD PRESSURE CONTROL AND DYSLIPIDAEMIA

Figure 8.1.4(a): Cumulative Distribution of pre dialysis diastolic blood pressure, PD patients 1997-2012

Source: 20th MDTR Report 2012, NRR

0

.25

.5

.75

1

Cum

ulat

ive

dist

ribu

tion

60 65 70 75 80 85 90 95 100Pre dialysis Diastolic Blood Pressure (mmHg)

1997 2000 20042008 2012

Page 13: CHAPTER 8: BLOOD PRESSURE CONTROL AND DYSLIPIDAEMIA

Figure 8.1.4(b): Mean of pre dialysis diastolic blood pressure, PD patients 1997-2012

0

10

20

30

40

50

60

70

80

90N

o. o

f pat

ient

s

'97 '98 '99 '00 '01 '02 '03 '04 '05 '06 '07 '08 '09 '10 '11 '12Year

Mean of pre dialysis diastolic blood pressure 1997-2012

Mean of pre dialysis DBP, PD patients

Source: 20th MDTR Report 2012, NRR

Page 14: CHAPTER 8: BLOOD PRESSURE CONTROL AND DYSLIPIDAEMIA

Table 8.1.5(a): Median systolic blood pressure among HD patients, HD centres

Year Number of centres Min 5th

Centile LQ Median UQ 95th Centile Max

1997 45 120.4 133.6 140.1 145.2 152 158 165.71998 48 131.7 135.9 140.8 145.8 150.7 158.6 159.21999 73 134.2 135.8 143.9 148.8 153.5 163.8 170.52000 103 130.1 137.3 142.8 148 153.5 162.8 167.72001 126 126.9 136.9 143 150 155 161.9 180.52002 145 128.3 136.7 144.7 149.2 154 162 169.72003 176 126.7 136.6 144.9 150 156.4 163.3 173.72004 217 122.1 137.5 145.8 150 155.5 162.8 169.82005 241 121.7 137.1 143.9 151 155 162.1 171.82006 287 130.8 138.8 146.5 151.5 156.6 163 180.32007 320 131.7 140.2 147.4 152.3 157 164.8 174.12008 378 130 140.4 147.4 152.3 157 164.2 174.32009 424 132.9 139.7 146.7 151.1 155.7 162.4 173.22010 459 130.1 140 146.4 150.3 155.5 163.3 1752011 513 125.5 139.4 147.2 151.6 156.1 163.6 175.32012 563 125.8 140.7 147.8 151.9 156.1 163.3 171

Source: 20th MDTR Report 2012, NRR

Page 15: CHAPTER 8: BLOOD PRESSURE CONTROL AND DYSLIPIDAEMIA

Figure 8.1.5 (a): Variation in median systolic blood pressure among HD patients, HD centres 2012

Source: 20th MDTR Report 2012, NRR

80

90

100

110

120

130

140

150

160

170

180

190

200

Systo

lic b

lood p

ressure

, m

mH

g

0 50 100 150 200 250 300 350 400 450 500 550Centre

(lower quartile, upper quartile)Median systolic blood pressure

Page 16: CHAPTER 8: BLOOD PRESSURE CONTROL AND DYSLIPIDAEMIA

Table 8.1.5 (b): Median diastolic blood pressure among HD patients, HD centres

Year Number of centres Min 5th

Centile LQ Median UQ 95th Centile Max

1997 45 76.4 80 82 84.3 85.5 87.5 94.31998 48 75.1 78.6 82 83.6 86.1 89 90.61999 73 75.5 78.7 81.5 83.8 86 89 91.32000 103 75.1 76.5 80 82.3 84.7 88.4 94.22001 126 73.9 76 79.8 81.9 83.7 87.5 91.32002 145 72.3 75.9 79.4 81.4 83.6 87.6 90.82003 176 73.4 75 78.7 80.4 83.6 86.4 93.32004 217 70.2 74 78.3 80.8 82.7 86.8 88.42005 241 69 73.1 78.1 80.8 82.7 86.6 90.32006 287 68 74.4 77.8 80.5 83.1 86.7 1012007 320 70.1 73.2 77.8 80.2 82.9 87.2 124.52008 378 66.8 73.3 77 79.6 82.5 86.8 92.32009 424 68.5 72.8 76.6 79.3 82 86.4 134.12010 459 68.6 72.3 76.5 79.1 82 86 142.22011 513 69 72.6 76.3 78.7 81.9 86.3 143.12012 563 66.3 71.3 75.8 78.5 81.5 86.5 124.2

Source: 20th MDTR Report 2012, NRR

Page 17: CHAPTER 8: BLOOD PRESSURE CONTROL AND DYSLIPIDAEMIA

Figure 8.1.5 (b): Variation in median diastolic blood pressure among HD patients, HD centres 2012

Source: 20th MDTR Report 2012, NRR

60

80

100

120

140

160

Dia

sto

lic b

lood p

ressure

, m

mH

g

0 50 100 150 200 250 300 350 400 450 500 550Centre

(lower quartile, upper quartile)Median diastolic blood pressure

Page 18: CHAPTER 8: BLOOD PRESSURE CONTROL AND DYSLIPIDAEMIA

Table 8.1.5 (c): Proportion of HD patients with pre dialysis blood pressure < 140/90 mmHg, HD centres

Year Number of centres Min 5th

Centile LQ Median UQ 95th Centile Max

1997 45 11 15 29 36 45 63 861998 48 9 14 27 35 41.5 54 721999 73 3 8 23 31 41 55 672000 103 0 12 21 32 43 60 732001 126 0 12 20 31 42 58 732002 145 0 10 21 29 39 59 702003 176 3 9 20.5 27 39 58 812004 217 0 8 20 29 38 56 822005 241 5 11 20 28 39 56 952006 287 0 9 17 24 35 52 802007 320 0 8 17 26 33 47.5 802008 378 0 8 17 24 33 48 732009 424 0 10 18 27 35 52 802010 459 0 7 18 26 35 50 872011 513 0 7 17 24 33 50 942012 563 0 8 17 24 33 47 80

Source: 20th MDTR Report 2012, NRR

Page 19: CHAPTER 8: BLOOD PRESSURE CONTROL AND DYSLIPIDAEMIA

Figure 8.1.5 (c): Variation in proportion of HD patients with pre dialysis blood pressure < 140/90 mmHg, HD centres 2012

Source: 20th MDTR Report 2012, NRR

0

10

20

30

40

50

60

70

80

90

100

% p

atie

nts

, m

mH

g

0 50 100 150 200 250 300 350 400 450 500 550Centre

(lower quartile, upper quartile)% with pre dialysis blood pressure <=140/90 mmHg

Page 20: CHAPTER 8: BLOOD PRESSURE CONTROL AND DYSLIPIDAEMIA

Table 8.1.6(a): Median systolic blood pressure among PD patients, PD centres

Year Number of centres Min 5th

Centile LQ Median UQ 95th Centile Max

1997 7 124 124 139.4 142.5 150 151.6 151.61998 9 111.6 111.6 135 138.6 140.8 147.5 147.51999 9 117 117 133.7 137.8 140 152.8 152.82000 11 116.2 116.2 132.4 134.9 137.7 149.1 149.12001 11 119.6 119.6 130.7 137.5 138.8 149 1492002 15 123.9 123.9 134.5 140 144.5 148.2 148.22003 18 123.8 123.8 132.4 142.4 144.3 151.8 151.82004 18 122.9 122.9 134.5 139.8 143.3 149.7 149.72005 19 121.9 121.9 134.8 136.6 142.2 158 1582006 22 112.7 118.3 130.2 136.3 140.4 146 154.92007 22 115.9 116.3 135.2 138.2 141.8 148 153.52008 23 115.6 118.1 136 138.9 141.6 147.7 147.92009 24 113.5 116.3 135.8 138.3 143.9 150 161.52010 26 114.3 115.6 130.4 138.6 143.3 146.3 147.92011 28 112.5 114.2 129 139.8 141.6 146.5 147.52012 28 113 114.2 132.7 140.6 143.7 149.8 156.7

Source: 20th MDTR Report 2012, NRR

Page 21: CHAPTER 8: BLOOD PRESSURE CONTROL AND DYSLIPIDAEMIA

Figure 8.1.6 (a): Variation in median systolic blood pressure among PD patients, PD centres 2012

Source: 20th MDTR Report 2012, NRR

100

110

120

130

140

150

160

170

Systo

lic b

lood p

ressure

, m

mH

g

0 2 4 6 8 10 12 14 16 18 20 22 24 26 28Centre

(lower quartile, upper quartile)Median systolic blood pressure

Page 22: CHAPTER 8: BLOOD PRESSURE CONTROL AND DYSLIPIDAEMIA

Table 8.1.6 (b): Median diastolic blood pressure among PD patients, PD centres

Year Number of centre Min 5th

Centile LQ Median UQ 95th Centile Max

1997 7 82.5 82.5 85.3 86 86 88.7 88.71998 9 73.2 73.2 85.1 85.8 86 87 871999 9 76.8 76.8 82.3 84.3 85.8 86.8 86.82000 11 73.1 73.1 80.5 83 84.4 88 882001 11 78 78 80.9 83.4 84.8 88 882002 15 76.8 76.8 81.8 83.3 85.7 89.5 89.52003 18 77.5 77.5 81.2 82.9 84 88 882004 18 77.5 77.5 80.8 83.2 84.2 87 872005 19 74.4 74.4 80.3 82.9 84.2 86.3 86.32006 22 71.6 74 78.9 81.2 82.4 86.7 88.42007 22 68.8 77.3 78.9 80 82.3 83.2 86.92008 23 73.4 76 78.3 80 82 85.5 86.62009 24 72.9 73.3 78.6 79.4 82.6 84.3 87.92010 26 74 74.7 77.3 79.5 82.4 86.5 87.42011 28 74.1 74.5 78.3 79.6 81.9 85.1 86.92012 28 73.5 75.7 78.6 80 83.2 87.2 91

Source: 20th MDTR Report 2012, NRR

Page 23: CHAPTER 8: BLOOD PRESSURE CONTROL AND DYSLIPIDAEMIA

Figure 8.1.6 (b): Variation in median diastolic blood pressure among PD patients, PD centres 2012

Source: 20th MDTR Report 2012, NRR

65

70

75

80

85

90

95

100

Dia

sto

lic b

lood p

ressure

, m

mH

g

0 2 4 6 8 10 12 14 16 18 20 22 24 26 28Centre

(lower quartile, upper quartile)Median diastolic blood pressure

Page 24: CHAPTER 8: BLOOD PRESSURE CONTROL AND DYSLIPIDAEMIA

Table 8.1.6 (c): Proportion of PD patients with pre dialysis blood pressure < 140/90 mmHg, PD centres

Year Number of centre Min 5th

Centile LQ Median UQ 95th Centile Max

1997 7 26 26 35 41 46 59 591998 9 36 36 44 47 49 100 1001999 9 30 30 42 52 57 100 1002000 11 24 24 52 58 63 95 952001 11 36 36 46 52 64 87 872002 15 19 19 33 47 56 91 912003 18 28 28 38 46.5 65 74 742004 18 30 30 38 47 56 73 732005 19 23 23 43 55 62 92 922006 22 18 36 43 59 68 100 1002007 22 27 27 44 54 68 91 912008 23 27 29 43 53 58 85 1002009 24 10 29 40 50 57.5 92 962010 26 30 34 38 51 64 88 1002011 28 29 31 43 46 70.5 97 1002012 28 5 26 39 45 63.5 90 96

Source: 20th MDTR Report 2012, NRR

Page 25: CHAPTER 8: BLOOD PRESSURE CONTROL AND DYSLIPIDAEMIA

Figure 8.1.6 (c): Variation in proportion of PD patients with pre dialysis blood pressure ≤140/90 mmHg, PD centres 2012

Source: 20th MDTR Report 2012, NRR

0

10

20

30

40

50

60

70

80

90

100

% p

atients

, m

mH

g

1 3 5 7 9 11 13 15 17 19 21 23 25 27Centre

(lower quartile, upper quartile)% with pre dialysis blood pressure <=140/90 mmHg

Page 26: CHAPTER 8: BLOOD PRESSURE CONTROL AND DYSLIPIDAEMIA

Table 8.2.1: Distribution of serum cholesterol, HD patients 1997-2012

YearNumber

of patients

Mean SD Median LQ UQ

% Patients serum cholesterol (mmol/L)  

<3.5 3.5-<5.3 5.3-<6.2 ≥6.2

1997 1158 5.1 1.4 5.1 4.2 5.9 8 47 26 191998 1166 5.1 1.3 5 4.2 5.8 7 51 24 171999 1871 5 1.3 4.9 4.1 5.7 10 53 22 152000 2954 5 1.2 4.9 4.2 5.8 8 52 24 162001 3898 5.1 1.3 4.9 4.2 5.8 8 51 25 162002 4751 5 1.2 4.9 4.2 5.7 9 53 25 132003 5806 4.8 1.1 4.8 4.1 5.5 9 58 22 112004 6710 4.7 1.1 4.7 4 5.4 11 59 22 82005 7906 4.7 1.1 4.6 4 5.3 12 60 20 82006 10139 4.6 1.1 4.6 3.9 5.3 14 61 18 72007 11347 4.6 1.1 4.5 3.8 5.2 14 62 18 62008 13820 4.5 1.1 4.4 3.8 5.2 15 62 17 62009 15904 4.6 1.1 4.5 3.8 5.2 14 62 17 62010 17653 4.6 1.1 4.5 3.8 5.2 14 62 18 72011 20672 4.5 1.1 4.4 3.8 5.1 16 63 15 62012 23470 4.5 1.1 4.4 3.8 5.1 16 63 15 5

Source: 20th MDTR Report 2012, NRR

Page 27: CHAPTER 8: BLOOD PRESSURE CONTROL AND DYSLIPIDAEMIA

Figure 8.2.1: Cumulative distribution of cholesterol, HD patients 1997-2012

Source: 20th MDTR Report 2012, NRR

0

.25

.5

.75

1

Cum

ulat

ive

dist

ribu

tion

3 4 5 6 7 8Serum cholesterol (mmol/L)

1997 2000 20042008 2012

Page 28: CHAPTER 8: BLOOD PRESSURE CONTROL AND DYSLIPIDAEMIA

Table 8.2.2: Distribution of serum cholesterol, PD patients 1997-2012

YearNumber

of patients

Mean SD Median LQ UQ

% Patients serum cholesterol (mmol/L)  

<3.5 3.5-<5.3 5.3-<6.2 ≥6.2

1997 420 6.1 1.4 6 5.1 6.9 2 25 30 431998 348 6 1.4 5.9 5 6.8 3 29 28 411999 434 5.7 1.4 5.6 4.9 6.4 3 36 30 312000 526 5.9 1.6 5.7 4.9 6.7 3 31 30 362001 581 5.8 1.4 5.7 4.8 6.6 2 35 28 352002 766 5.6 1.4 5.5 4.6 6.4 4 36 30 292003 1104 5.4 1.4 5.3 4.4 6.1 5 44 28 232004 1230 5.3 1.4 5.2 4.4 6.1 5 47 27 212005 1242 5.2 1.3 5 4.3 5.9 5 53 24 182006 1395 5.2 1.4 5.1 4.3 5.9 6 50 26 182007 1629 5.1 1.3 5.1 4.2 5.9 8 48 26 182008 1902 5.2 1.4 5 4.3 5.9 7 50 24 182009 2016 5.3 1.5 5.1 4.3 6 6 48 26 202010 2186 5.2 1.4 5.1 4.3 6 7 48 25 202011 2350 5.1 1.3 5 4.2 5.8 8 50 25 172012 2684 5.1 1.4 4.9 4.2 5.8 7 52 24 17

Source: 20th MDTR Report 2012, NRR

Page 29: CHAPTER 8: BLOOD PRESSURE CONTROL AND DYSLIPIDAEMIA

Figure 8.2.2: Cumulative distribution of cholesterol (mmol/L), PD patients 1997-2012

Source: 20th MDTR Report 2012, NRR

0

.25

.5

.75

1

Cum

ula

tive

dist

ribu

tion

3 4 5 6 7 8 9Serum cholesterol (mmol/L)

1997 2000 20042008 2012

Page 30: CHAPTER 8: BLOOD PRESSURE CONTROL AND DYSLIPIDAEMIA

Table 8.2.3: Distribution of serum triglyceride, HD patients 1997-2012

YearNumber

of patients

Mean SD Median LQ UQ

% Patients serum triglyceride (mmol/L)  

<1.7 1.7-<2.3 2.3-<3.5 ≥3.5

1997 1074 2.1 1.4 1.8 1.3 2.5 45 24 18 121998 1089 2.2 1.5 1.8 1.3 2.6 42 26 20 121999 1633 2.1 1.3 1.7 1.2 2.5 49 21 18 112000 2391 2.1 1.4 1.7 1.3 2.6 48 22 19 122001 3162 2.1 1.4 1.7 1.2 2.5 48 22 17 132002 3861 2.1 1.4 1.8 1.2 2.5 47 22 18 122003 4710 2 1.3 1.7 1.2 2.5 48 23 18 112004 5607 2 1.2 1.7 1.2 2.4 51 23 17 102005 6950 2 1.3 1.7 1.2 2.4 50 22 18 102006 9522 2 1.3 1.6 1.2 2.3 54 21 16 92007 10882 1.9 1.2 1.6 1.1 2.3 55 21 16 82008 12927 1.9 1.2 1.6 1.1 2.3 56 20 15 82009 15183 1.9 1.3 1.6 1.1 2.3 54 21 16 92010 16970 1.9 1.3 1.6 1.1 2.3 54 21 16 92011 19724 1.9 1.2 1.6 1.1 2.3 55 21 16 82012 22780 1.9 1.2 1.6 1.1 2.3 55 21 16 9

Source: 20th MDTR Report 2012, NRR

Page 31: CHAPTER 8: BLOOD PRESSURE CONTROL AND DYSLIPIDAEMIA

Figure 8.2.3: Cumulative distribution of serum triglyceride, HD patients 1997-2012

Source: 20th MDTR Report 2012, NRR

0

.25

.5

.75

1

Cum

ulat

ive

dist

ribu

tion

0 1 2 3 4 5Serum triglyceride (mmol/L)

1997 2000 20042008 2012

Page 32: CHAPTER 8: BLOOD PRESSURE CONTROL AND DYSLIPIDAEMIA

Table 8.2.4: Distribution of serum triglyceride, PD patients 1997-2012

YearNumber

of patients

Mean SD Median LQ UQ

% Patients serum triglyceride (mmol/L)  

<1.7 1.7-<2.3 2.3-<3.5 ≥3.5

1997 413 2.6 1.9 2.2 1.4 3 36 22 25 181998 344 2.4 1.8 1.8 1.3 3 42 22 17 191999 421 2.4 1.6 2 1.4 3 38 25 18 192000 520 2.7 2.2 2.1 1.5 3 33 24 23 212001 576 2.6 1.8 2 1.4 3 36 22 22 202002 767 2.5 1.7 2 1.4 3 39 21 22 182003 1100 2.3 1.6 1.8 1.2 2.8 45 20 21 142004 1223 2.2 1.6 1.8 1.3 2.6 47 23 17 132005 1241 2.2 1.5 1.8 1.3 2.7 43 24 18 142006 1391 2.2 1.6 1.7 1.2 2.6 47 21 18 132007 1625 2.1 1.4 1.8 1.3 2.6 45 24 19 122008 1907 2.2 1.5 1.8 1.3 2.7 45 21 20 142009 2017 2.2 1.6 1.8 1.3 2.7 46 21 20 142010 2177 2.1 1.4 1.8 1.3 2.5 47 23 18 112011 2365 2 1.3 1.7 1.2 2.3 51 23 17 92012 2667 2 1.3 1.7 1.2 2.5 48 23 19 10Source: 20th MDTR Report 2012, NRR

Page 33: CHAPTER 8: BLOOD PRESSURE CONTROL AND DYSLIPIDAEMIA

Figure 8.2.4: Cumulative distribution of serum triglyceride, PD patients 1997-2012

Source: 20th MDTR Report 2012, NRR

0

.25

.5

.75

1

Cum

ulat

ive

dist

ribu

tion

0 1 2 3 4 5 6 7Serum triglyceride (mmol/L)

1997 2000 20042008 2012

Page 34: CHAPTER 8: BLOOD PRESSURE CONTROL AND DYSLIPIDAEMIA

Table 8.2.5 (a): Median serum cholesterol level among HD patients, HD centres

Year Number of centres Min 5th

Centile LQ Median UQ 95th Centile Max

1997 34 4.1 4.2 4.6 5 5.3 5.7 5.81998 31 4.2 4.4 4.8 5 5.3 5.5 5.61999 45 3.5 4.3 4.6 4.8 5.1 5.6 5.82000 76 4 4.2 4.7 4.9 5.2 5.5 5.72001 97 4.1 4.4 4.7 5 5.1 5.9 6.32002 122 4.3 4.5 4.7 4.9 5.1 5.6 6.42003 152 4.1 4.3 4.6 4.8 5 5.3 5.62004 187 3.8 4.2 4.5 4.7 4.9 5.4 6.12005 211 3.8 4.1 4.4 4.6 4.8 5.2 5.62006 268 3.3 3.9 4.3 4.6 4.8 5.2 5.92007 292 3.6 4 4.3 4.5 4.8 5.1 5.42008 346 3.2 3.8 4.2 4.5 4.7 5.1 6.32009 384 3.5 4 4.3 4.5 4.8 5.2 5.62010 423 3.5 4 4.3 4.5 4.8 5.1 5.72011 488 3.5 3.9 4.2 4.4 4.6 4.9 5.72012 545 3.5 3.9 4.2 4.4 4.6 4.9 5.9

Source: 20th MDTR Report 2012, NRR

Page 35: CHAPTER 8: BLOOD PRESSURE CONTROL AND DYSLIPIDAEMIA

Figure 8.2.5 (a): Variation in median serum cholesterol level among HD patients, HD centres 2012

Source: 20th MDTR Report 2012, NRR

3

3.5

4

4.5

5

5.5

6

6.5

7

7.5

8

Seru

m c

hole

ste

rol, m

mol/L

0 50 100 150 200 250 300 350 400 450 500 550Centre

(lower quartile, upper quartile)Median serum cholesterol

Page 36: CHAPTER 8: BLOOD PRESSURE CONTROL AND DYSLIPIDAEMIA

Table 8.2.5(b): Proportion of HD patients with serum cholesterol < 5.3mmol/L, HD centres

Year Number of centre Min 5th

Centile LQ Median UQ 95th Centile Max

1997 34 32 35 46 55.5 67 79 911998 31 20 30 49 58 68 86 1001999 45 32 36 56 63 75 83 862000 76 36 40 51.5 61.5 69.5 86 942001 97 14 31 53 60 69 80 832002 122 22 40 55 63 70 77 932003 152 38 44 58.5 67 76 83 922004 187 25 44 61 69 77 89 972005 211 34 50 65 73 81 91 1002006 268 29 52 67 74.5 82 92 1002007 292 36 57 68.5 75 84 92 1002008 346 30 56 69 77 84 92 1002009 384 35 52 68 76 84 93 1002010 423 27 55 68 76 84 92 1002011 488 36 58 72 80 86 95 1002012 545 31 62 73 80 86 93 100

Source: 20th MDTR Report 2012, NRR

Page 37: CHAPTER 8: BLOOD PRESSURE CONTROL AND DYSLIPIDAEMIA

Figure 8.2.5 (b): Variation in proportion of patients with serum cholesterol < 5.3mmol/L, HD centres 2012

Source: 20th MDTR Report 2012, NRR

10

20

30

40

50

60

70

80

90

100

% p

atients

0 50 100 150 200 250 300 350 400 450 500 550Centre

(lower 95% CI, upper 95% CI)% with serum cholesterol <5.3 mmol/L

Page 38: CHAPTER 8: BLOOD PRESSURE CONTROL AND DYSLIPIDAEMIA

Table 8.2.5 (c): Median serum triglyceride level among HD patients, HD centres

Year Number of centres Min 5th

Centile LQ Median UQ 95th Centile Max

1997 33 1.3 1.3 1.6 1.8 1.9 2.5 2.91998 28 1.4 1.4 1.6 1.8 2 2.1 2.31999 39 1.2 1.3 1.5 1.7 1.9 2.4 2.52000 59 1 1.3 1.5 1.8 1.9 2.6 2.82001 85 1 1.4 1.5 1.7 1.9 2.4 3.82002 97 1.1 1.4 1.6 1.8 2 2.3 3.22003 127 1.2 1.3 1.5 1.7 1.9 2.2 2.52004 161 1 1.3 1.5 1.7 1.8 2.2 32005 193 0.9 1.3 1.5 1.6 1.8 2.2 2.62006 255 1 1.3 1.5 1.6 1.8 2.3 42007 279 0.8 1.2 1.4 1.6 1.8 2.1 2.92008 320 1 1.2 1.4 1.6 1.7 2 2.52009 365 1 1.2 1.4 1.6 1.8 2.1 2.42010 401 0.9 1.2 1.5 1.6 1.8 2.2 2.92011 470 1 1.2 1.4 1.6 1.8 2.1 6.32012 528 0.8 1.2 1.5 1.6 1.8 2.1 2.8

Source: 20th MDTR Report 2012, NRR

Page 39: CHAPTER 8: BLOOD PRESSURE CONTROL AND DYSLIPIDAEMIA

Figure 8.2.5 (c): Variation in median serum triglyceride level among HD patients, HD centers 2012

Source: 20th MDTR Report 2012, NRR

0

1

2

3

4

5

6

7

8

9

10

seru

m tri

gly

ceri

de, m

mol/L

0 50 100 150 200 250 300 350 400 450 500 550Centre

(lower quartile, upper quartile)Median serum triglyceride

Page 40: CHAPTER 8: BLOOD PRESSURE CONTROL AND DYSLIPIDAEMIA

Table 8.2.5(d): Proportion of HD patients with serum triglyceride < 2.1mmol/L, HD centres

Year Number of centres Min 5th

Centile LQ Median UQ 95th Centile Max

1997 33 23 35 59 65 75 88 941998 28 44 50 56.5 62.5 71.5 80 831999 39 41 47 60 68 73 88 922000 59 23 38 58 65 73 84 862001 85 27 45 59 68 77 86 912002 97 27 45 55 67 71 83 932003 127 27 44 58 69 75 90 1002004 161 19 47 59 70 80 88 972005 193 29 45 60 67 74 84 932006 255 14 46 64 70 77 89 1002007 279 36 52 63 71 79 89 1002008 320 36 54 64 71.5 80 88 1002009 365 38 50 63 71 78 89 1002010 401 27 50 63 70 77 88 1002011 470 0 50 64 71 79 89 1002012 528 28 50 63 70 78.5 88 94

Source: 20th MDTR Report 2012, NRR

Page 41: CHAPTER 8: BLOOD PRESSURE CONTROL AND DYSLIPIDAEMIA

Figure 8.2.5 (d): Variation in proportion of patients with serum triglyceride < 2.1mmol/L, HD centers 2012

Source: 20th MDTR Report 2012, NRR

10

20

30

40

50

60

70

80

90

100

% p

atie

nts

0 50 100 150 200 250 300 350 400 450 500 550Centre

(lower 95% CI, upper 95% CI)% with serum triglyceride <2.1 mmol/L

Page 42: CHAPTER 8: BLOOD PRESSURE CONTROL AND DYSLIPIDAEMIA

Table 8.2.6 (a): Median serum cholesterol level among PD patients, PD centres

Year Number of centres Min 5th

Centile LQ Median UQ 95th Centile Max

1997 6 5.8 5.8 5.9 5.9 6.1 6.1 6.11998 6 4.8 4.8 5.6 5.8 6.1 6.2 6.21999 8 5.1 5.1 5.4 5.7 5.8 6 62000 10 5.2 5.2 5.4 5.6 5.9 6.4 6.42001 10 5 5 5.6 5.9 6.2 6.2 6.22002 15 4.9 4.9 5.4 5.5 5.7 6.2 6.22003 18 4.5 4.5 5 5.3 5.7 5.9 5.92004 18 4.6 4.6 4.9 5.3 5.5 6.1 6.12005 19 4.4 4.4 4.7 5 5.4 5.9 5.92006 21 4.4 4.6 4.8 5.1 5.3 6.1 6.22007 21 4.5 4.5 4.9 5.2 5.4 5.5 6.12008 22 4.3 4.5 4.8 5.1 5.4 5.5 5.82009 23 4.7 4.7 4.8 5.1 5.4 5.9 6.72010 25 4.6 4.7 4.9 5.1 5.4 6 7.32011 27 4.3 4.4 4.9 5.1 5.3 5.9 7.22012 27 4.3 4.4 4.8 4.9 5.3 6 7.8

Source: 20th MDTR Report 2012, NRR

Page 43: CHAPTER 8: BLOOD PRESSURE CONTROL AND DYSLIPIDAEMIA

Figure 8.2.6 (a): Variation in median serum cholesterol level among PD patients, PD centres 2012

Source: 20th MDTR Report 2012, NRR

3.5

4

4.5

5

5.5

6

6.5

7

7.5

8

8.5

Seru

m c

hole

ste

rol, m

mol/L

0 2 4 6 8 10 12 14 16 18 20 22 24 26Centre

(lower quartile, upper quartile)Median serum cholesterol

Page 44: CHAPTER 8: BLOOD PRESSURE CONTROL AND DYSLIPIDAEMIA

Table 8.2.6 (b): Proportion of PD patients with serum cholesterol < 5.3mmol/L, PD centres

Year Number of centres Min 5th

Centile LQ Median UQ 95th Centile Max

1997 6 24 24 25 26 30 33 331998 6 24 24 27 32 37 53 531999 8 10 10 36 39.5 45 56 562000 10 11 11 18 31 43 54 542001 10 22 22 30 33.5 44 59 592002 15 13 13 29 38 44 80 802003 18 23 23 38 47.5 59 83 832004 18 26 26 42 49.5 60 69 692005 19 27 27 46 57 69 74 742006 21 20 25 47 57 63 72 792007 21 29 40 45 53 65 74 862008 22 30 41 46 55 68 73 742009 23 9 31 44 52 66 72 772010 25 9 27 43 51 60 71 722011 27 0 23 45 53 66 73 882012 27 11 20 48 59 68 78 81

Source: 20th MDTR Report 2012, NRR

Page 45: CHAPTER 8: BLOOD PRESSURE CONTROL AND DYSLIPIDAEMIA

Figure 8.2.6 (b): Variation in proportion of patients with serum cholesterol < 5.3mmol/L, PD centres 2012

Source: 20th MDTR Report 2012, NRR

10

20

30

40

50

60

70

80

90

100

% p

atients

0 2 4 6 8 10 12 14 16 18 20 22 24 26Centre

(lower 95% CI, upper 95% CI)% with serum cholesterol <5.3 mmol/L

Page 46: CHAPTER 8: BLOOD PRESSURE CONTROL AND DYSLIPIDAEMIA

Table 8.2.6 (c): Median serum triglyceride level among PD patients, PD centres

Year Number of centres Min 5th

Centile LQ Median UQ 95th Centile Max

1997 6 1.7 1.7 1.9 2.1 2.2 2.4 2.41998 6 1.2 1.2 1.5 1.7 1.9 2.1 2.11999 8 1.6 1.6 1.9 2 2.1 2.6 2.62000 10 1.8 1.8 2 2.3 2.5 2.6 2.62001 10 1.5 1.5 1.9 2 2.1 3 32002 15 1.5 1.5 1.8 1.9 2 2.4 2.42003 18 1.2 1.2 1.7 1.8 1.9 2.3 2.32004 18 1.3 1.3 1.7 1.8 1.8 2.2 2.22005 19 1.4 1.4 1.6 1.9 2 2.2 2.22006 21 1.1 1.4 1.6 1.8 1.9 2.1 2.62007 21 1.2 1.5 1.7 1.8 1.9 2.1 2.72008 22 1.3 1.5 1.7 1.8 2 2.2 2.32009 23 1.4 1.5 1.7 1.8 1.9 2.2 2.52010 24 1.4 1.5 1.6 1.8 1.9 2.1 2.12011 27 1.2 1.4 1.6 1.6 1.8 2.1 2.22012 27 1.4 1.4 1.6 1.7 1.9 2.4 2.7

Source: 20th MDTR Report 2012, NRR

Page 47: CHAPTER 8: BLOOD PRESSURE CONTROL AND DYSLIPIDAEMIA

Figure 8.2.6 (c): Variation in median serum triglyceride level among PD patients, PD centres 2012

Source: 20th MDTR Report 2012, NRR

1

1.5

2

2.5

3

3.5

seru

m tri

gly

ceri

de, m

mol/L

0 2 4 6 8 10 12 14 16 18 20 22 24 26Centre

(lower quartile, upper quartile)Median serum triglyceride

Page 48: CHAPTER 8: BLOOD PRESSURE CONTROL AND DYSLIPIDAEMIA

Table 8.2.6 (d): Proportion of PD patients with serum triglyceride < 2.1mmol/L, PD centres

Year Number of centres Min 5th

Centile LQ Median UQ 95th Centile Max

1997 6 40 40 46 52 56 61 611998 6 51 51 55 61 70 85 851999 8 37 37 53.5 56 60.5 64 642000 10 18 18 42 49 54 62 622001 10 27 27 50 53 58 68 682002 15 38 38 52 56 57 76 762003 18 49 49 54 59 62 92 922004 18 47 47 60 62.5 64 88 882005 19 40 40 53 60 68 91 912006 21 33 52 54 61 65 78 822007 21 40 52 60 64 66 80 812008 22 48 48 56 60 65 82 842009 23 27 48 54 60 67 70 712010 24 49 50 59.5 62 68.5 74 772011 27 41 53 61 66 73 80 932012 27 42 44 59 64 71 81 86

Source: 20th MDTR Report 2012, NRR

Page 49: CHAPTER 8: BLOOD PRESSURE CONTROL AND DYSLIPIDAEMIA

Figure 8.2.6 (d): Variation in proportion of patients with serum triglyceride < 2.1mmol/L, PD centres 2012

Source: 20th MDTR Report 2012, NRR

0

10

20

30

40

50

60

70

80

90

100

% p

atients

0 2 4 6 8 10 12 14 16 18 20 22 24 26Centre

(lower 95% CI, upper 95% CI)% with serum triglyceride <2.1 mmol/L


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