Clonorchis sinensis

Clonorchis sinensisServando Tabjan

IntroductionETYMOLOGY: Clon = branched and orchis = testis along with sinensis = representing China. HISTORY: This trematode was originally described from the bile passages of a Chinese carpenter working in Calcutta, India. It was described in Japan in 1883 and was recognized as being endemic in south China in 1908 by Heanley. Cats were first noted to be infected in Japan (Ijima, 1887).

Common Name:

Chinese Liver Fluke Oriental Liver Fluke

http://www.redorbit.com/education/reference_library/animal_kingdom/miscellaneuos/1112846356/chinese-liver-fluke-clonorchis-sinensis/ http://www.aavp.org/wiki/trematodes-2/trematodes-pancreatic-duct-bile-duct-gall-bladder/opisthorchidae/clonorchis-sinensis/

2Morphology Adult

Morphology Egg

MiracidumCercariaMorphology

Metacercariaencysted metacercaria ofClonorchis sinensisnormally found in fish but occasionally in crustaceans5

LIFECYCLE Mode of transmission, laboratory diagnosis 6

Clonorchiasis Clonorchiasis, with a common bile duct carcinoma, in a 75-year-old man7Pathology and Symptomatology

1st phase: Desquamation of epithelial cells

2nd phase: Hyperplasia

3rd phase:

Adenomatous tissue formation

4th phase:

8Symptoms Irregular appetite Gastrointestinal disturbances EdemaHepatomegaly

Mild, essentially, symptomless, progressive9Treatment: Chloroquine

Prevention and ControlThorough cooking of freshwater fish

cholang10