Date post: | 13-Apr-2018 |
Category: |
Documents |
Upload: | adie-brian |
View: | 214 times |
Download: | 0 times |
of 65
7/26/2019 cochranedatabasesystrev.doc
1/170
Continuous support for women during childbirth (Review)
Copyright 2012 The Cochrane Collaboration !ublished by "ohn
Continuous support for women duringchildbirth (Review)
Hodnett ED, Gates S, Hofmeyr GJ, Sakala C
This is a reprint of a Cochrane review, prepared and maintained by The Cochrane Collaboration andpublished in TheCochraneLibrary
2012, Issue 10
http://ww w.thec oc hranelibrary.c om
http://www.thecochranelibrary.com/http://www.thecochranelibrary.com/http://www.thecochranelibrary.com/http://www.thecochranelibrary.com/http://www.thecochranelibrary.com/http://www.thecochranelibrary.com/http://www.thecochranelibrary.com/http://www.thecochranelibrary.com/http://www.thecochranelibrary.com/http://www.thecochranelibrary.com/http://www.thecochranelibrary.com/http://www.thecochranelibrary.com/http://www.thecochranelibrary.com/http://www.thecochranelibrary.com/http://www.thecochranelibrary.com/http://www.thecochranelibrary.com/http://www.thecochranelibrary.com/http://www.thecochranelibrary.com/http://www.thecochranelibrary.com/http://www.thecochranelibrary.com/http://www.thecochranelibrary.com/http://www.thecochranelibrary.com/http://www.thecochranelibrary.com/http://www.thecochranelibrary.com/http://www.thecochranelibrary.com/http://www.thecochranelibrary.com/7/26/2019 cochranedatabasesystrev.doc
2/170
Continuous support for women during childbirth (Review)
Copyright 2012 The Cochrane Collaboration !ublished by "ohn
7/26/2019 cochranedatabasesystrev.doc
3/170
Continuous support for women during childbirth (Review)
Copyright 2012 The Cochrane Collaboration !ublished by "ohn
i
T ' * + , C + - T * - T%
!"#!$ . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1
"%&T$"CT . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1
'("I) (")*+"*! &+"$- . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 2
%"C*$+)# . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 2
%!CTI!& . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
!T#& . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
$!&+(T& . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 3
4i5ure 1. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 10
4i5ure 2. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 11
#I&C+&&I) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 16
"+T/$&7C/)C(+&I/)& . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 18
"C)9(!#*!!)T& . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1
$!4!$!)C!& . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1
C"$"CT!$I&TIC& 4 &T+#I!& . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 22
#"T" ")# ")"(-&!& . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 6;
"nalysis 1.1. Comparison 1 Continuoussupport versus usual care < all trials, utcome 1 "ny anal5esia/anaesthesia. . 63
"nalysis 1.2. Comparison 1 Continuoussupport versus usual care < all trials, utcome 2 $e5ional anal5esia/anaesthesia. 6=
"nalysis 1.;. Comparison 1 Continuoussupport versus usual care < all trials, utcome ; &ynthetic o>ytocin durin5
labour. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 80
"nalysis 1.. Comparison 1 Continuoussupport versus usual care < all trials, utcome (abour len5th. . . . . . 81
"nalysis 1.6. Comparison 1 Continuoussupport versus usual care < all trials, utcome 6 &pontaneous va5inal birth. 82
"nalysis 1.8. Comparison 1 Continuoussupport versus usual care < all trials, utcome 8 Instrumental va5inal birth. 8;
"nalysis 1.. Comparison 1 Continuoussupport versus usual care < all trials, utcome Caesarean birth. . . . . 8
"nalysis 1.3. Comparison 1 Continuoussupport versus usual care < all trials, utcome 3 'erineal trauma. . . . . 86
"nalysis 1.=. Comparison 1 Continuoussupport versus usual care < all trials, utcome = (ow 6
7/26/2019 cochranedatabasesystrev.doc
4/170
Continuous support for women during childbirth (Review)
Copyright 2012 The Cochrane Collaboration !ublished by "ohn
ii
"nalysis 2.. Comparison 2 Continuoussupport versus usual care perience. . . . . . . . . . . . . . . . . . . 31
"nalysis 2.3. Comparison 2 Continuoussupport versus usual care
7/26/2019 cochranedatabasesystrev.doc
5/170
Continuous support for women during childbirth (Review)
Copyright 2012 The Cochrane Collaboration !ublished by "ohn
iii
I&T/$- . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 112
C)T$I%+TI)& 4 "+T/$& . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 112
#!C("$"TI)& 4 I)T!$!&T . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 11;
&+$C!& 4 &+''$T . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 11;
I)#!? T!$& . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 11;
7/26/2019 cochranedatabasesystrev.doc
6/170
Continuous support for women during childbirth (Review)
Copyright 2012 The Cochrane Collaboration !ublished by "ohn
1
[Intervention Review]
Continuous support for women duringchildbirth
!llen # odnett1 , &imon *ates2 , * ustus ofmeyr; , Carol
&a@ala
1 (awrence &. %loomber5 4aculty of )ursin5, +niversity of Toronto, Toronto, Canada. 2 9arwic@ Clinical Trials +nit, #ivision
of ealth &ciences, 9arwic@ edical &chool, The +niversity of 9arwic@, Coventry, +. ; #epartment of bstetrics and
*ynaecolo5y, !ast (ondon ospital Comple>, +niversity of the 9itwatersrand, +niversity of 4ort are, !astern Cape #epartment
of ealth, !ast (ondon, &outh "frica. Childbirth Connection, )ew -or@, +&"
Contact address: !llen # odnett, (awrence &. %loomber5 4aculty of)ursin5, +niversity of Toronto, 166 Colle5e &treet, &uite
1;0, Toronto, ntario, 6T 1'3, Canada.elle n.hodnettAutoronto.c a.
Editorial grou! Cochrane 're5nancy and Childbirth *roup.
"u#li$ation status and date! )ew search for studies and content updated Bno chan5e to conclusions, published in Issue 10,
2012.Review $ontent assessed as u%to%date! 1 "u5ust 2012.
Citation! odnett !#, *ates &, ofmeyr *, &a@ala C. Continuous support for women durin5 childbirth. Cochrane Databaseof
Systematic Reviews 2012, Issue 10. "rt. )o.: C#00;88. #I:10.1002/1861363.C#00;88.pub.
Copyri5ht D 2012 The Cochrane Collaboration. 'ublished by ohn 9iley E &ons,(td.
&a$kground
% T R C T
istorically, women have been attended and supported by other women durin5 labour. owever, in hospitals worldwide,
continuous support durin5 labour has become the e>ception rather than the routine.
'#(e$tives
'rimary: to assess the effects of continuous, onetracted the data. 9e sou5ht additional information from the trial authors.
9e used random< effects analyses for comparisons in which hi5h hetero5eneity was present, and we reported results usin5 the
avera5e ris@ ratio B$$ for cate5orical data and mean difference B# for continuous data.
mailto:[email protected]:[email protected]:[email protected]:[email protected]:[email protected]:[email protected]:[email protected]:[email protected]:[email protected]:[email protected]:[email protected]:[email protected]:[email protected]:[email protected]:[email protected]:[email protected]:[email protected]:[email protected]:[email protected]:[email protected]:[email protected]:[email protected]:[email protected]7/26/2019 cochranedatabasesystrev.doc
7/170
Continuous support for women during childbirth (Review)
Copyright 2012 The Cochrane Collaboration !ublished by "ohn
2
*ain results
Twenty
7/26/2019 cochranedatabasesystrev.doc
8/170
CI 0.36 to 0.=8, re5ional anal5esia B$$ 0.=;, =6H CI 0.33 to 0.==, or a baby with a low fiveception rather than
the norm. This may contribute to the dehumanisation of women7s childbirth e>periences. odern obstetric care freGuently
subects women to institutional routines, which may have adverse effects on the pro5ress of labour. &upportive care durin5 labour
may involve emotional support, comfort measures, information and advocacy. These may enhance physiolo5ic labour processes as
well as women7s feelin5s of control and competence, and thus reduce the need for obstetric intervention. The review of studies
included 2; trials B22providin5 data, from 18 countries, involvin5 more than 16,000 women in a wide ran5e of settin5s and
circumstances. The continuous support was provided either by hospital staff Bsuch as nurses or midwives, women who were not
hospital employees and had nopersonal relationship to the labourin5 woman Bsuch as doulas or women who were provided with a
modest amount of 5uidance, or by companions of the woman7s choice from her social networ@ Bsuch as her husband, partner,
mother, or friend. 9omen who received continuous labour support were more li@ely to 5ivebirth 7spontaneously7, i.e. 5ivebirth
with neither caesarean nor vacuum nor forceps. In addition, women were less li@ely to usepain medications, were more li@ely to be
satisfied, and had sli5htly shorter labours. Theirbabies were less li@ely to have low five
7/26/2019 cochranedatabasesystrev.doc
9/170
cisions to modify the bac@5round and methods. The authors
de< cided that the best approach would be to write a new
protocol for the review. The new protocol was submitted
throu5h the peer review process of the Cochrane 're5nancy and
Childbirth *roup and has subseGuently evolved into a review
that has been updated.
istorically and cross
7/26/2019 cochranedatabasesystrev.doc
10/170
periences Bin hi5htentbuffer such stressors.
The second theoretical e>planation does not focus on a
particular type of birth environment. $ather, it describes two
pathways < enhancedpassa5e of the fetus throu5h thepelvis and
soft tissues, as well as decreased stress response < by which labour
support may reduce the li@elihood of operative birth and
subseGuent compli< cations, and enhance women7s feelin5s of
control and satisfaction with their childbirth e>periences
Bodnett 2002a. !nhanced fe< topelvic relationships may be
accomplished by encoura5in5 mo< bility and effective use of
5ravity, supportin5 women to assume their preferred positions
and recommendin5 specific positions for specific situations.
&tudies of the relationships amon5 fear and an>< iety, the stress
response and pre5nancy complications have shown that an>iety
durin5 labour is associated with hi5h levels of the stress hormone
epinephrine in the blood, which may in turn lead to ab< normal
fetal heart rate patterns in labour, decreased uterine contraction or forceps, episiotomy and
less morbidity associated with these, and may increase mobility
durin5 labour and spontaneous birth BCaton 2002.
" systematic review e>aminin5 factors associated with women7s
sat< isfaction with the childbirth e>perience su55ests that
continuous support can ma@e a substantial contribution to this
satisfaction. 9hen women evaluate their e>perience, four factors
predominate: the amount of support from care5ivers, the Guality
of relationships with care5ivers, bein5 involved with decisionpectations or havin5 e>periences thate>ceed e>pectations Bodnett 2002a.
Clarification of the effects of continuous support durin5
labour, overall and within specific circumstances, is important in
li5ht ofpublic and social policies and pro5rams that encoura5e
this type of care. 4or e>ample, the Con5ress in +ru5uay passed a
law in 2001 decreein5 that all women have the ri5ht to
companionship durin5 labour. In several low< and middletra cost
to families or health systems, it is important to understand their
effectiveness as providers of continuous labour support.
In addition to Guestions about the impact of the type of
provider of labour support, there are other Guestions about the
effectiveness of support, includin5 its impact under a variety of
environmental conditions, and whether its effects are mediated
by when contin< uous support be5ins Bearly versus active
labour.
Childbearin5 women,policy
7/26/2019 cochranedatabasesystrev.doc
13/170
ii not a staff member but not part of the woman7s
social networ@ andpresent solely for thepurpose of providin5
continuous supportF or
iii aperson chosenby the woman from family
members and friends.
;. 9hether the continuous support be5ins early or later
in labour.
* T 6 + 4%
Criteria for considering studies forthis review
Types of studies
"ll controlled trials comparin5 continuous labour support by
ei< ther a familiar or unfamiliar person Bwith or without
healthcare professional Gualifications with usual care, in
which there was random allocation to treatment and control
5roups, were consid< ered for inclusion in the review.
Types of participants
're5nant women, in
labour.
Types of interventions
The form of care that was evaluated was continuous presence
and support durin5 labour and birth. The person providin5 the
sup< port could have Gualifications as a healthcare professional
Bnurse, midwife or trainin5 as a doula or childbirth educator,
or be a family member, spouse/partner, friend or stran5erwith little or no special trainin5 in labour support. The control
5roup received usual care, as defined by the trialists. In all cases,
7usualcare7did not involve continuous intrapartum support,but
it could involve other measures, such as routine epidural
anal5esia, to help women to cope with labour.
Types of outcome
measures
Theoretically, continuous support can have many diversephysiotract data. 4or eli5ible studies, data
were independently e>tractedby twopeople Beither two review
authors or an author and an assistant, usin5 the a5reed form.9e resolved discrepancies throu5h discussion. 9e entered data
into $eview ana5er software B$evan 2011 and chec@ed for
accuracy. 9hen information re5ardin5 any of the above was
unclear, we attempted to contact authors of the ori5inal
reports to provide further details.
ssessment of ris8 of bias inincluded studies
4or each study, at least two review authors independently
assessed ris@ of bias, usin5 the criteria outlined in the Cochrane
Handbook for SystematicReviewsofInterventionsBi55ins 2011.
9e would have resolved any disa5reement by discussion or by
involvin5 a third assessor.
http://www.mrw.interscience.wiley.com/cochrane/clabout/articles/PREG/frame.htmlhttp://www.mrw.interscience.wiley.com/cochrane/clabout/articles/PREG/frame.htmlhttp://www.mrw.interscience.wiley.com/cochrane/clabout/articles/PREG/frame.htmlhttp://www.mrw.interscience.wiley.com/cochrane/clabout/articles/PREG/frame.htmlhttp://www.mrw.interscience.wiley.com/cochrane/clabout/articles/PREG/frame.htmlhttp://www.mrw.interscience.wiley.com/cochrane/clabout/articles/PREG/frame.htmlhttp://www.mrw.interscience.wiley.com/cochrane/clabout/articles/PREG/frame.htmlhttp://www.mrw.interscience.wiley.com/cochrane/clabout/articles/PREG/frame.htmlhttp://www.mrw.interscience.wiley.com/cochrane/clabout/articles/PREG/frame.htmlhttp://www.mrw.interscience.wiley.com/cochrane/clabout/articles/PREG/frame.htmlhttp://www.mrw.interscience.wiley.com/cochrane/clabout/articles/PREG/frame.html7/26/2019 cochranedatabasesystrev.doc
16/170
(1) %e9uence generation (chec8ing for
possible selection bias)
9e described for each included study the method used to
5enerate the allocation seGuence in sufficient detail to allow an
assessment of whether it shouldproduce comparable 5roups.
9e assessed the method as: low ris@ ofbias Bany truly randomprocess, e.5. random
number tableF computer random number5eneratorF
hi5h ris@ ofbias Bany nonclusions from the analysis. 9e stated whether
attrition and e>clusions were reported, the numbers included in
the analysis at each sta5e Bcompared with the total randomised
participants, rea< sons for attrition or e>clusion where reported,
and whether miss< in5 data were balanced across 5roups or were
related to outcomes. To be included in the review, data on a
5iven outcome had to be available for at least 30H of those who
were ori5inally randomised.
7/26/2019 cochranedatabasesystrev.doc
17/170
4or outcomes collected postplicit ud5ements about whether studies are at hi5h
ris@ of bias, accordin5 to the criteria 5iven in the Handbook
Bi55ins
2011. 9ith reference to B1 to B8 above, we assessed the
li@ely ma5nitude and direction of the bias and whether we
considered it is li@ely to impact on the findin5s. 9e e>plored
the impact of the level of bias throu5h underta@in5 sensitivity
analyses < see &ensitivity analysis.
7/26/2019 cochranedatabasesystrev.doc
18/170
easures of treatmenteffect
4ichotomous
data
4or dichotomous data, we presented results as summary ris@
ratio with =6H confidence intervals.
Continuousdata
"ll but one pre
7/26/2019 cochranedatabasesystrev.doc
19/170
ssessment ofheterogeneity
9e assessed statistical hetero5eneity in each meta
7/26/2019 cochranedatabasesystrev.doc
20/170
() +ne subgroup analysis that concerns
characteristics of the providers of labour
support
Trials in which the care5ivers were employees of the
institution, compared with trials in which the care5ivers were not
employees and were not members of the woman7ssocialnetwor@, compared with trials in which theproviders were not
employees and were lay people chosen by theparticipants Be.5.
husband/partner, friend, close relative.
(C) +ne subgroup analysis that concerns
differences in the timing of onset of continuous
support
Trials in which continuous labour support be5anprior to or
durin5 early labour Bas defined by trial authors, comparedwith
trials in which continuous support be5an in activelabour.
%ecause few of the trial reports contained all of the information
needed for the above sub5roup analyses, we contacted the trial
au< thors in an attempt to verify thepresence/absenceof routine
elec< tronic fetal monitorin5 B!4, the presence/absence of
epidural anal5esia and timin5 of onset of continuous support.
9e e>cluded some studies included in the primary comparisons
from the sub< 5roup analyses concernin5 the use of !4
because their status re5ardin5 !4 use was un@nown. 4or tests
of differences between these sub5roups, we recalculated the
overall analysisby includin5 only the studies in which !4 use
was @nown.The seven primary outcomes and one secondary outcomewere
used in the sub5roup analyses. 9hile normally, sub5roup analyses
are restricted to primary outcomes, we also included the
outcome of caesarean delivery, because there is widespread
concern about escalatin5 caesarean rates worldwide, and sub5roup
analyses could be helpful to policy ma@ers in decisions about
the provision of continuous labour support. Thusthe outcomes
in the sub5roup analyses were: any anal5esia/anaesthesia,
synthetic o>ytocin dur< in5 labour, spontaneous va5inal birth,
caesareanbirth, postpartum depression, ne5ative ratin5s of the
birth e>perience, admission to special care nursery, and
breastfeedin5 at one to two monthsposttremely low, we compared the results of randomeded
7/26/2019 cochranedatabasesystrev.doc
21/170
%ensitivityanalysis
9eperformed sensitivity analyses, for the primary outcomes, in
instances in which there was a hi5h ris@ of bias associated with
the Guality of included trials.
R * % ' T %
4escription of
studies
&ee: Characteristics of included studiesF Characteristics of
e>cluded studiesF Characteristics of studies awaitin5 classificationF
Characteristics of on5oin5 studies.
.ncludedstudies
'lease see Characteristics of included studies table. 9hile 2;
trials met the inclusion criteria, one trial BThomassen 200;
provided no usable outcome data. 9e do not describe it here,
but provide details in the Characteristics of included studies
table.
"ll 22 trials Bn Q 16,233 that provided usable outcome data
were conducted in hospitals. The trials were conducted in
"ustralia, %el< 5ium, %otswana, %raJil, Canada, Chile, 4inland,
4rance, *reece, *uatemala, e>ico, )i5eria, &outh "frica,
&weden, Thailand, and the +nited &tates, under widely disparate
hospital conditions, re5< ulations and routines. There was
remar@able consistency in the descriptions of continuous support
across all trials. In all instances the intervention included
continuous or nearly continuous pres< ence, at least durin5 activelabour. Twenty of the 22 trials that pro< vided usable outcome
data Ball e>cept Co5an 1=33 and #ic@inson
2002 also included specific mention of comfortin5 touch and
words ofpraise and encoura5ement.
In 11 trials B%reart < %el5ium 1==2F %reart < 4rance 1==2F
Campbell 2008F Co5an 1=33F #ic@inson 2002F *a5non 1==F
emmin@i 1==0aF emmin@i 1==0bF odnett 1=3=F odnett
2002F c*rath 2003, hospital policy permitted women to be
accompanied by their husbands/partners or other family memcluded because they
did not provide any us< able data B*ordon 1===F emmin@i
1==0c. 'lease refer to table Characteristics of e>cluded studies
for details.
Ris8 of bias in includedstudies
The trials were of 5enerally 5ood Guality B4i5ure 1F 4i5ure
2.
7/26/2019 cochranedatabasesystrev.doc
23/170
7/26/2019 cochranedatabasesystrev.doc
24/170
Continuous support for women during childbirth (Review)
Copyright 2012 The Cochrane Collaboration !ublished by "ohn
1
,igure 1 ethodological 9uality summary@ review authorsA Budgements about each
methodological 9uality item for each included study
7/26/2019 cochranedatabasesystrev.doc
25/170
Continuous support for women during childbirth (Review)
Copyright 2012 The Cochrane Collaboration !ublished by "ohn
1
,igure 2 ethodological 9uality graph@ review authorsA Budgements about each
methodological 9uality item presented as percentages across all
included studies
llocation
$andom seGuence 5eneration: Twelve trials were at unclear
ris@ of bias B%reart < %el5ium 1==2F %reart < 4rance 1==2F
%reart < *reece 1==2F Co5an 1=33F #ic@inson 2002F
emmin@i 1==0aF emmin@i 1==0bF ennell 1==1F laus
1=38F adi 1===F c*rath 2003F Thomassen 200; because
they did not describe the method of random assi5nment. !leven
trials described usin5 a computer random number 5enerator or
referred to a random number table B%ru55emann 200F
Campbell 2008F *a5non 1==F odnett 1=3=F odnett 2002F
ofmeyr 1==1F ashanian 2010F (an5er 1==3F orhason trials Bn Q =681, the support
was provided by a member of the hospital staffF $$ 1.08, =6H
CI 1.01 to 1.11. In three trials Bn Q 1013, the support was
providedby a woman who was not a member of the staff and
was not part of the woman7ssocial networ@F $$ 0.8=, =6H CI
0.60 to 0.=. In si> trials Bn Q 201, the support was
provided by a member of the woman7ssocial networ@F $$
0.==, =6H CI
0.=8 to 1.01. ChiP for the sub5roup comparison Q 11.8, ' Q
0.00;, "nalysis 6.2.
Thus the effects of continuous support on use of synthetic
o>ytocin durin5 labour did not appear to be influenced by
policies about thepresence of companions, use of routine !4,
or availability of epidural anal5esia. The effectiveness of
continuous support in reducin5 the li@elihood of intrapartum
o>ytocin seemed to be stron5est when theprovider was neither
a staff member nor part of the woman7ssocial networ@.
'ut$ome!sontaneous vaginal #irt)
1. 'olicies about companions: In nine trials Bn Q 10,33=companions werepermittedF $$ 1.0;, =6H CI 1.00 to 1.06.
In ten trials Bn Q ;;2= companions were not permittedF
$$1.11,
=6H CI 1.0 to 1.18. ChiP for the sub5roup comparison Q
11.32, ' R 0.001, "nalysis 2.;.
2. "vailability of epidural anal5esia: In 1; trials Bn Q 12,82,
epidural anal5esia was routinely availableF $$ 1.0, =6H CI 1.01
to 1.08. In si> trials Bn Q 168 epidural anal5esia was not
routinely availableF $$ 1.11, =6H CI 1.08 to 1.1. ChiP for the
sub5roup comparison Q 8.6=, ' Q 0.01, "nalysis ;.;.
7/26/2019 cochranedatabasesystrev.doc
32/170
;. $outine use of !4: In ei5ht trials Bn Q =1 !4
was routineF $$ 1.0;, =6H CI 1.01 to 1.08. In seven trials Bn
Q
1=1; !4 was not routineF $$ 1.11, =6H CI 1.08 to 1.1.
In four trials Bn Q 2681, thepolicy about routine !4 is not
@nownF $$ 1.0, =6H CI 1.01 to 1.1;. ChiP for the sub5roup
comparison Q 3.68, ' Q 0.01, "nalysis .;.
. 'rovider characteristics: in nine trials Bn Q 10,31; the
support was provided by a member of the hospital staffF $$
1.0;, =6H CI 1.01 to 1.08. In five trials Bn Q 1=;6 the
support was provided by a woman who was not part of the
hospital staff nor part of the woman7ssocial networ@F $$ 1.12,
=6H CI 1.0 to 1.1. In five trials Bn Q 10, the support was
provided by a member of the woman7ssocial networ@F $$
1.0, =6H CI 0.== to 1.16. ChiP for the sub5roup comparison
Q =.=, ' Q 0.00, "nalysis 6.;.
Thus the effectiveness of continuous support in increasin5 the
li@elihood of spontaneous va5inal birth appeared to be
stron5er when hospital policies did not permit companions,
when epidural anal5esia was not available, when !4 was not
routine, and when the support provider was neither a staff
member nor part of the woman7ssocial networ@.
'ut$ome!$aesarean #irt)
1. 'olicies about companions: in 11 trials Bn Q 11,;28
companions werepermittedF $$ 0.=, =6H CI 0.36 to 1.0;. In
11 trials Bn Q ;3= companions were not permittedF $$ 0.6,
=6H CI 0.86 to 0.38. ChiP for the sub5roup comparison Q
8.8, ' Q 0.01, "nalysis 2..
2. "vailability of epidural anal5esia: in 1 trials Bn Q 1;,08,
epidural anal5esia was routinely availableF $$ 0.=;, =6H CI0.38 to 1.02. In seven trials Bn Q 20, epidural anal5esia was
not routinely availableF $$ 0.6, =6H CI 0.; to 0.83. In one
very small trial Bn Q ;, we were unable to determine if
epidural anal5esia was routinely availableF $$ 1.0, =6H CI
0.1 to
1;.=3. ChiP for the sub5roup comparison Q 1=.;0, ' R
0.0001, "nalysis ;..
;. $outine use of !4: in nine trials Bn Q 10,12;, !4
was routineF $$ 0.=2, =6H CI 0.3; to 1.01. In ei5ht trials Bn Q
26 !4 was not routineF $$ 0.88, =6H CI 0.66 to 0.=. In
five trials Bn Q 26=6, it is not @nown whether !4 was
routineF $$ 1.08, =6H CI 0.3 to 1.;;. ChiP for the sub5roup
comparison Q 12.3, ' Q 0.002, "nalysis ... 'rovider characteristics: in nine trials Bn Q 10,38,
the support was provided by a member of the hospital
staffF $$
0.=6, =6H CI 0.36 to1.06. In seven trials Bn Q 2;;0, the
support was provided by a woman who was not a member of
the hospital staff and not part of the woman7ssocial networ@F
$$
0.2, =6H CI 0.80 to 0.38. In si> trials Bn Q 206=, the
support was provided by a member of the woman7ssocial
networ@F $$
0.3;, =6H CI 0.8= to 1.01. ChiP for the sub5roup comparison Q
8.33, ' Q 0.0;, "nalysis 6..
7/26/2019 cochranedatabasesystrev.doc
33/170
Thus the effectiveness of continuous support in reducin5 the
li@e< lihood of caesareanbirth appeared to be stron5er in settin5s
where companions were not permitted, epidural anal5esia was
not rou< tinely available and !4 was not routine, and when
the provider was neither a staff member nor part of the woman7s
social networ@.
'ut$ome!admission to se$ial $are nursery
1. 'olicies about companions: in two trials Bn Q ;23,
companions werepermittedF $$ 0.==, =6H CI 0.3 to 1.1. In
five trials Bn Q 168=, companions were not permittedF $$
0.=1,
=6H CI 0.1 to 1.1. ChiP for the sub5roup comparison Q 0.23,
' Q 0.80, "nalysis 2.6.
2. "vailability of epidural anal5esia: in five trials Bn Q 3;30
epidural anal5esia was routinely availableF $$ 0.=3, =6H CI 0.36
to 1.1;. In two trials Bn Q 61 epidural anal5esia was not
routinely availableF $$ 0.28, =6H CI 0.03 to 0.33. ChiP for the
sub5roup comparison Q .61, ' Q 0.0;, "nalysis ;.6.
;. $outine use of !4: in three trials Bn Q 0 !4 was
routineF $$ 0.=, =6H CI 0.3 to 1.11. In three trials Bn Q
2= !4 was not routineF $$ 0.3, =6H CI 0.21 to 1.12. In
one trial Bn Q 23, it is not @nown whether !4 was routineF
$$
1.=3, =6H CI 0.8 to 6.13. ChiP for the sub5roup comparison Q
.8, ' Q 0.0=, "nalysis .6.
. 'rovider characteristics: in three trials Bn Q 23, the
support was provided by a member of the hospital staffF
$$
0.==, =6H CI 0.3, 1.1. In two trials Bn Q 32=, the support
was provided by a woman who was not a member of the
hospital staff and not part of the woman7ssocial networ@F $$
0.38, =6H CI 0.88 to 1.12. In two trials Bn Q 80 the support
wasprovided by a member of the woman7ssocial networ@F $$
1.0, =6H CI
0.8 to 2.=;. ChiP for the sub5roup comparison Q 1., ' Q
0.2, "nalysis 6.6.
Thus the effectiveness of continuous support in reducin5 the
li@e< lihood of admission of the newborn to a special care
nursery ap< peared to be stron5er in settin5s in which epidural
anal5esia was not routinely available, but effectiveness did not
appear to be in< fluenced by policies about companions or
routine !4, or byprovider characteristics.
'ut$ome!negatives ratings of0negativeviews a#out t)e #irt)
e1erien$e
1. 'olicies about companions: in five trials Bn Q 38;=
companions werepermittedF $$ 0.0, =6H CI 0.82 to 0.3.
In si> trials Bn Q 26;= companions were not permittedF $$
0.82,
=6HCI 0.68 to 0.8=. ChiP for the sub5roup comparison Q 2.0;,
' Q 0.16, "nalysis 2..
2. "vailability of epidural anal5esia: in nine trials Bn Q 10,0
epidural anal5esia was routinely availableF $$ 0.0, =6H CI 0.8
to 0.. In two trials Bn Q epidural anal5esia was not
routinely availableF $$ 0.66, =6H CI 0.3 to 0.8;. ChiP for the
sub5roup comparison Q .=2, ' 0.0006, "nalysis ;..
7/26/2019 cochranedatabasesystrev.doc
34/170
;. $outine use of !4: four trials Bn Q 8 were
conducted in settin5s with routine !4F $$ 0.8, =6H CI
0.80 to 0.8. 4our trials Bn Q 110 were conducted in settin5s
in which !4 was not routineF $$ 0.80, =6H CI 0.6; to 0.83.
Three trials Bn Q
1= were in settin5s in which the use of routine !4 is not
@nownF $$ 0.3, =6H CI 0.86 to 1.03. ChiP for the
sub5roup comparison Q 6.66, ' Q 0.08, "nalysis ..
. 'rovider characteristics: in four trials Bn Q 316 support
providers were hospital staffF $$ 0.3, =6H CI 0.; to 1.0;. In
three trials Bn Q 1;26 theproviders were not hospital staff and
not part of the woman7ssocial networ@F $$ 0.88, =6H CI 0.6
to 0.. In four trials Bn Q 103,providers werepart of the
woman7ssocial networ@F $$ 0.6, =6H CI 0.61 to 0.8. ChiP
for the sub5roup comparison Q 18., ' Q 0.000;, "nalysis
6..
Thus the effectiveness of continuous support in reducin5 the
li@e< lihood of dissatisfaction with or ne5ative views of the
childbirth e>perience appeared to be stron5er in settin5s in
which epidural anal5esia was not routinely available, and when
the provider was neither a staff member nor part of the
woman7ssocial networ@.
4 . % C % % . +-
This review summarises results of 22 trials involvin5 16,233
women, conducted in 18 countries under a wide variety of
circum< stances. Continuousonecellent. 4or all outcomes in which summary statistics were
computed, comparisons of fi>ed< effect and random
7/26/2019 cochranedatabasesystrev.doc
35/170
)IC! Intrapartum Care 200F &*C 1==6. The results of the
primary comparison in the current review offer continuedustifiperiences.
There remains relatively little information about the effects of
continuous intrapartum support on mothers7 and babies7 health
and well
7/26/2019 cochranedatabasesystrev.doc
37/170
ucational materials for the %etter %irths Initiative include a
videopresentation on childbirth companions which is available
in the 9orld ealth r5aniJation $eproductive ealth (ibrary
B9/
2010. It can be accessed free of char5e on the Internet in
"rabic, Chinese, 4rench, !n5lish, &panish, $ussian and
ietnamese and is distributed on C# to health wor@ers in
resource
7/26/2019 cochranedatabasesystrev.doc
38/170
#ec 1;
7/26/2019 cochranedatabasesystrev.doc
39/170
differentpolicies for the mana5ement of labour. arly
H!manDevelo#ment 1==2F43:;0=S12.
%reart *, li@a
7/26/2019 cochranedatabasesystrev.doc
40/170
$o!rnal o fPsychosomatic'bstetricsand (ynaecolo)y 1==0F22:
2;=S60.
Hodnett 23
7/26/2019 cochranedatabasesystrev.doc
41/170
effect on stress hormone levels. $o!rnal of 'bstetricsand
(ynaecolo)y 1==6F2;:13S31. ofmeyr *, )i@odem C, 9olman 9(, Chalmers
%!, ramer T. Companionship to modify the clinical
birth environment: effects onpro5ress andperceptions of
labour, andbreastfeedin5. &ritish$o!rnal of 'bstetrics
and (ynaecolo)y 1==1F3
7/26/2019 cochranedatabasesystrev.doc
42/170
*adi 2333 {published and unpublished data}
adi %C, &andall , %ennett $, ac(eod C.
!ffects of female relative support in labor: a
randomiJed controlled trial.&irth 1===F49:S3.
*$Grat) 455< {published data only}
c*rath &, ennell . " randomiJed controlled
trial of continuous labor support for middle
7/26/2019 cochranedatabasesystrev.doc
43/170
Continuous support for women during childbirth (Review)
Copyright 2012 The Cochrane Collaboration !ublished by "ohn
2
labor #attern 4thesis5. $hode Island: +niversity of $hode
Island, 2000.
&rown 4557 {published data only}
%rown , ofmeyr *, )i@odem C, &mith ,
*arner '. 'romotin5 childbirth companions in &outh
"frica: a randomised pilot study. &%C%edicine200F;:.
Dalal 4559 {published data only}
#alal $, $athna@umar, &antamani. %irth companion
and mother < apreliminary report abstractU. =th "ll
India Con5ress of bstetrics and *ynaecolo5yF 2008 an
8
7/26/2019 cochranedatabasesystrev.doc
44/170
Continuous support for women during childbirth (Review)
Copyright 2012 The Cochrane Collaboration !ublished by "ohn
2
Sosa 23ryon 2399 {published data only}
Tryon '". +se of comfort measures as support durin5 labor.
"!rsin)Research1=88F2;B2:10=S13.
@)ang 2339 {published data only}
Mhan5 C(, -u M, 4en5 ". &tudy of
psycholo5ical nursin5 to easepain durin5 labour.
Chinese$o!rnal of"!rsin)1==8F
:2B8:;11S;.
Referen$es to studies awaiting assessment
Dong 4553 {published data only}
#on5 ?, Ni , u (, (uo ?, Mhu -, Cai . The
effects of air sac combined with nitrous o>ide and
#oula companyin5 delivery in va5inal delivery.
International $o!rnal of (ynecolo)y and 'bstetrics
200=F257:&163S&16=.
Huang 455: {published data only}
uan5 ?, ?ian5 ?-, &hen $*, &han5 N, Mhu (', Nian
?, et al.&tudy on intrapartum service model durin5 normal
labor. Ch!n)-H!a8! Chan 2o TsaChih 4Chinese$o!rnal
of 'bstetrics (ynecolo)y5 200;F:
7/26/2019 cochranedatabasesystrev.doc
45/170
and reduces postpartum problems for hospitaliJed pre5nant
women. Contem#orary"!rse2011F:7B2:1=S6=.
Referen$es to ongoing studies
Janssen {published data only}
anssen '. Impact of doula support on intrapartumoutcomes for women under5oin5 a va5inalbirth after
cesarean Bvbac.
http://c linic a ltria ls.5ov/ct2/sho w/re cord/)C T 012180= 3
Baccessed 16 4ebruary 2012.
+dditional referen$es
+nim%Somua) 4522
"nim
7/26/2019 cochranedatabasesystrev.doc
46/170
=laus 4554
laus , ennell , laus '. Thedo!la
book3 how a trained labor com#anion can hel# yo!
have a shorter, easier and healthier birth. 2nd
!dition. Cambrid5e, ": 'erseus %oo@s, 2002.
-ederman 237presentations.
Trial in %el5ium: n Q 28 B1;; permanent supportF 1;1 control
Interventions 'ermanentpresence of a midwife compared to varyin5 de5rees ofpresence. 4athers
were allowed to bepresent
utcomes >ytocin, epidural anal5esia, labour len5th, mode ofbirth, "p5ar scores, mothers7
views of their e>periences
)otes !pidural anal5esia was available and it is not @nown whether !4 was used routinely
Risk of bias
&ias +ut)ors,(udgement Suort for(udgement
$andom seGuence 5eneration Bselection
bias+nclear ris@ 9omen were 7randomly assi5ned7. The envelopes were
prepared by the co
7/26/2019 cochranedatabasesystrev.doc
49/170
&reart % 6ran$e 2334
ethods &ee %reart cept that mothers7views were not reported
)otes !pidural anal5esia was not available.)ot stated if !4 was used routinely
Risk of bias
&ias
$andom seGuence 5eneration Bselection
+ut)ors,(udgement
+nclear ris@
Suort for(udgement
9omen were 7randomlyassi5ned7. The envelopes were
bias by the copected behaviour when confronted with si5ns of tiredness, an>iety,
concern, cryin5, screamin5 and/or the woman7s feelin5s of inability to cope,
compliance with re5ulations and the possibility of reGuestin5 information from staff
7. in .8H of the
7/26/2019 cochranedatabasesystrev.doc
51/170
&ruggemann 4557 BContin!ed=
sample the woman7s companion was her partner, for 2=.6H it was hermother
The control 5roup received usual care where a companion durin5 labour and
delivery was not permitted
4or both 5roups labour and delivery care was provided 7accordin5 to the routine
protocol includin5 active mana5ement of labour Bearly amniotomy, use of o>ytocin,
intermittent !4 and systematic anal5esiaC7
utcomes &atisfaction with labour and delivery, perinatal and breastfeedin5 outcome in the 12
hours post delivery
)otes "ll women in labour at this hospital received epidural anal5esia as a routine practice.
Therefore, we did not include epidural anal5esia data in the
review
!4 was not used routinely.
Risk of bias
&ias +ut)ors,(udgement Suort for(udgement
$andom seGuence 5eneration Bselection
bias(ow ris@ 7Computer5enerated seGuence of random numbers.7
"llocation concealment Bselection bias i5h ris@ 7Individual assi5nment numbers were all placed in an
opaGue container to assure the concealment. The eli5ible
women who had a5reed to participate selected one of the
numbers once, and were therefore allocated to either
intervention 5roup or control accordin5 to the list.7
This process was open to selection bias as women could havere< pic@ed another number from the container. )o audit
process ispossible with this system of randomisation
%lindin5 Bperformance bias and detection
bias
"ll outcomes
i5h ris@ #ata collectionby author, who @new 5roup allocation.
Incomplete outcome data Battrition bias
"ll outcomes
(ow ris@ edical record data were collected and in
7/26/2019 cochranedatabasesystrev.doc
52/170
12 and ;3 wee@s75estation. They were considered low ris@, with no contraindications
7/26/2019 cochranedatabasesystrev.doc
53/170
Cam#ell 4559 BContin!ed=
to labour and had a female friend or relative willin5 to act as their lay doula. The
doula was in addition to support people of their own choosin5
Interventions Intervention: continuous supportby a female friend or relative who had had 2, 2t envelope. It was unclear whether the
research assistant enrollin5 the woman was the same one that
opened the envelope
%lindin5 Bperformance bias and detection
bias"ll outcomes
i5h ris@ edical record abstraction was done by the author who was
not blinded. The 8
7/26/2019 cochranedatabasesystrev.doc
54/170
%lindin5 Bperformance bias and detection (ow ris@
had fore@nowled5e of the treatment allocation scheme
edical record information collected by 7researchassistants
bias"ll outcomes
did not @now the 5roup membership of the women7
Incomplete outcome data Battrition bias
"ll outcomes
i5h ris@ 9ithdrawals occurred before analysis B8 B;0H in support
5roup and ; B21H in control. This resulted in a follow
7/26/2019 cochranedatabasesystrev.doc
55/170
Di$kinson 4554
ethods $CT, stratifiedby induced or spontaneous labour at trial entry
'articipants ==2 nulliparous women at term B== to continuous support and =; to control,
cephalic fetal presentation, cervical dilatation R 6 cm, in a hospital in 'erth, 9estern"ustralia
Interventions *roup 1: continuous physical and emotional support by midwifery staff, and women
were encoura5ed to use pharmacolo5ic and nonpharmacolo5ic alternatives to epidural
anal5esia.
*roup 2: continuous midwifery support was notprovided and women were
encoura5ed to have epidural anal5esia as theirprimary method of pain relief in labour
utcomes (abour len5th Be>pressed as median and interGuartile ran5e, epidural anal5esia,
mode of delivery, 6 min "p5ar score R , arterial cordp
)otes The stated purpose was to compare the effects of intrapartum anal5esic techniGues on
labour outcomes. Continuous midwifery support was conceptualised as an anal5esic
techniGue. %oth 5roups had access to opioids and nitrous o>ide. )o data were
presented about the number of women who used nopharmacolo5ic anal5esia. %ecause
the type of anal5esia used was a measure of compliance rather than an outcome, no data
on anal5esic outcomes are included in this review
It was not stated if other support person was allowed. epidural anal5esia was available
and !4 was used routinely
Risk of bias
&ias +ut)ors,(udgement Suort for(udgement
$andom seGuence 5eneration Bselectionbias
+nclear ris@ )o details about how the bloc@s of treatcluded women were
provided by the author
(abour len5th data were only available
for
3.H of the sam le 226 of 86 and
&elective reportin5 Breportin5 bias (ow ris@ "ll outcomes were reported on.
ther bias (ow ris@ )o other sources ofbias noted.
=laus 23
7/26/2019 cochranedatabasesystrev.doc
69/170
Continuous support for women during childbirth (Review)
Copyright 2012 The Cochrane Collaboration !ublished by "ohn
;
-anger 233< BContin!ed=
)otes 'artners and family members were not permitted. !pidural anal5esia was available but
it was not stated if !4 was used routinely
Risk of bias
&ias
$andom seGuence 5eneration Bselection
+ut)ors,(udgement
(ow ris@
Suort for(udgement
7Computer5enerated random number list7. 7Thetreatment se of envelopes that were shuffled in the woman7spresence.
9hen opened the envelope revealed a code indicatin5 her
5roup.7 "n assistant that was not involved in the recruitment
process shuf< fled the envelopes
%lindin5 Bperformance bias and detection
bias
"ll outcomes
i5h ris@ The researcher, who was involved in the recruitment of
partici
7/26/2019 cochranedatabasesystrev.doc
71/170
*$Grat) 455< BContin!ed=
utcomes Caesarean delivery, epidural anaesthesia, o>ytocin use, labour len5th, mode of
delivery, fever durin5 labour, satisfaction at 8 wee@spostpartum
)otes !pidural anal5esia was available and !4 was used routinely.
The author hasbeen contacted for data splitby study 5roup and Guestionnaire data
for the control 5roup
Risk of bias
&ias +ut)ors,(udgement Suort for(udgement
$andom seGuence 5eneration Bselection
bias
+nclear ris@ )o details stated.
"llocation concealment Bselection bias (ow ris@ 79hen the research cot seGuentially
numbered opaGue envelope to determine
random as< si5nment to the doula or
control 5roup7. The research co
7/26/2019 cochranedatabasesystrev.doc
72/170
*or)ason%&ello 4553
ethods $CT.
'articipants 80; women fromIbadan, )i5eria with anticipated va5inal delivery were enrolledbetween
;0 and ;2 wee@s7 5estation at an antenatal clinic B;06 to intervention and 2=3 tocontrol
from)ovember 2008 to arch 200
Interventions Those in the e>perimental 5roup were informed to brin5 someone of their choice to
act as a companion durin5 labour. n arrival in labour the accompanyin5 companions
were provided with an information leaflet that e>plained their responsibilities. These
included: 5entle massa5e of the woman7s bac@ durin5 contraction, reassurin5
words, spiritual support inform ofprayers and also actin5 as intermediary between the
woman and healthcare team. "fter studyin5 the leaflets, they were allowed to see@
clarifications. The information leaflet was also interpreted for those that are not literate.
The attendin5 midwife allowed and ensured companions performed their e>pected
duties throu5hout. The companions were told to offer continuous support < they were
to be by the patient7s side e>cept for feedin5 and use of toilet until two hours afterchildbirth. usbands were the most common support person B86.H
The women in the control 5roup had only routine care where relatives of patients
are usuallybarred from the labour ward
utcomes Caesarean section rate, active phase of labour duration, pain score, need for anal5esia,
need for o>ytocin au5mentation, time from delivery to initiation ofbreastfeedin5 and
the emotional e>perience durin5 labour
)otes !pidural anal5esia was not available and it was not stated whether !4 was used rouperimental 5roup tended to
be more educated B32H vs 3H with tertiary level and s@illed wor@ers B3H vs ;=H.This imbalance was noted and discussedby the authors
Risk of bias
&ias
$andom seGuence 5eneration Bselection
+ut)ors,(udgement
(ow ris@
Suort for(udgement
7The randomisation seGuence was 5enerated usin5 a table of
bias random numbers7
"llocation concealment Bselection bias (ow ris@ 7$andompermuted bloc@s of siJe four were used to ensure a
bal< anced desi5n.7 7%ased on the seGuence of treatments
5enerated usin5 this method, treatment 5roups B" and % were
written on pieces of cardboard paper and put into sealed
opaGue envelopes. !ach of the opaGue envelopes had a serial
number on it.7 7Two trained research assistants B$"s non)omassen 455: BContin!ed=
reported for 66/2 B8H of the
interven< tion 5roup and 8/2 B8H of
the control 5roup. $eason for the 1
KdropoutsL were preterm birth, induction,
or caesarean sec< tion Kfor medical
reasonsL, and participant withdrawal. )o
numbers are 5iven for in< dividual reasons,
or by 5roup, but it is clear that some
KdropoutsL were prior to labour and
others were durin5 labour. )umbers in
the report show the number of dropouts
was actually ;
&elective reportin5 Breportin5bias +nclear ris@ &le siJe was based on caesarean section
rate. The only outcome reported was emerorres 2333
ethods $CT.
'articipants ;6 women B21 in companion 5roup, 213 in control 5roup with a sin5leton
pre5nancy and considered to be lowperienced a va5inal birth
Control 5roup did not have companion.
%oth 5roups laboured in a room with other women where curtains were pulled forprivacy
utcomes Caesarean section, e>clusive breastfeedin5, duration of labour, mode of delivery, use
of o>ytocics, presence of meconium, re5ional anaesthesia,birth asphy>ia, "p5ar scores,
level of neonatal care, maternal satisfaction
)otes !pidural anal5esia was available. It was not stated if !4 was used routinely.
"uthors havebeen contacted for further details
Risk of bias
&ias +ut)ors,(udgement Suort for(udgement
7/26/2019 cochranedatabasesystrev.doc
75/170
>orres 2333 BContin!ed=
$andom seGuence 5eneration Bselection
bias
(ow ris@ Computer
7/26/2019 cochranedatabasesystrev.doc
76/170
?uenyong 4524 BContin!ed=
"llocation concealment Bselection bias (ow ris@ &ealed opaGue envelopes were used. !nvelopes were consecuytocin
level for 18 minutes postytocin, caesarean delivery, or forcepsLF or if the infant
was asphy>iated or ill at birth, etc. KIf a woman was removed, her 5roup assi5nment was inserted at random
into the pool of unused assi5nments. 9omen were enrolled in the study until there were 20 in the control
5roup and 20 in the e>perimental 5roup.L The total study sample of 12 mothers includes =6 in the control
5roup and ;2 in the e>perimental 5roup. Thusassi5nment was not random
Trueba 2000 #irect contact with investi5ator revealed that randomisation was not used. n arrival at the hospital,
women were as@ed if they wanted to have a doula. If they accepted, a doula was assi5ned to them. "lso
support was not continuous throu5hout active labour for most women, since admission to the labour ward
Band assi5nment of a doula did not usually occur until 3 cm
Tryon 1=88 )ot an $CT. K"fter a random start, the matched 5roups were alternately assi5ned to e>perimental and
control 5roups.L 9omen who developed severe complications in labour Bnumber not specified, such as fetal
distress, were dropped from the study
Mhan5 1==8 )ot a trial of continuous 1
7/26/2019 cochranedatabasesystrev.doc
78/170
Continuous support for women during childbirth (Review)
Copyright 2012 The Cochrane Collaboration !ublished by "ohn
ed, =6H CI
$is@ $atio BI, 4i>ed, =6H CI
0.6 0.86, 0.38U
&ubtotals only
6.1 ther support permitted 2 ;23 $is@ $atio BI, 4i>ed, =6H CI 0.== 0.3, 1.1U
6.2 ther support not
permitted
8 'ostpartum depression
6
2
168= $is@ $atio BI, 4i>ed, =6H CI
$is@ $atio BI, 4i>ed, =6H CI
0.=1 0.1, 1.1U
&ubtotals only
8.1 ther support permitted 1 668 $is@ $atio BI, 4i>ed, =6H CI 0.38 0.;, 1.02U
8.2 ther support not
permitted
1 1= $is@ $atio BI, 4i>ed, =6H CI 0.13 0.0=, 0.;8U
)e5ative ratin5 of/ne5ative
feelin5s about birth e>perience
.1 ther support permitted
11
6 38;=
$is@ $atio BI, 4i>ed, =6H CI
$is@ $atio BI, 4i>ed, =6H CI
&ubtotals only
0.0 0.82, 0.3U
.2 ther support not
permitted
8 26;= $is@ $atio BI, 4i>ed, =6H CI 0.82 0.68, 0.8=U
3 %reastfeedin5 at 1ed, =6H CI
$is@ $atio BI, 4i>ed, =6H CI
&ubtotals only
0.= 0.=2, 1.02U
3.2 ther support not
permitted
2 30 $is@ $atio BI, 4i>ed, =6H CI 1.06 0.=3, 1.1;U
Comarison :/ Continuous suort versus usual $are % availa#ility of eidural analgesia
'ut$ome or su#grou title
.o/ of
studies
.o/ of
arti$iants Statisti$al met)od Effe$t sie
1 "ny anal5esia/anaesthesia 1 $is@ $atio BI, 4i>ed, =6H CI &ubtotals only
1.1 !pidural anal5esia
routinely available
= 10333 $is@ $atio BI, 4i>ed, =6H CI 0.= 0.=8, 0.=3U
1.2 !pidural anal5esia not
routinely available
2 &ynthetic o>ytocin durin5 labour
6
16
182 $is@ $atio BI, 4i>ed, =6H CI
$is@ $atio BI, 4i>ed, =6H CI
0.3; 0.8=, 0.==U
&ubtotals only
2.1 !pidural anal5esia
routinely available
3 10683 $is@ $atio BI, 4i>ed, =6H CI 1.00 0.=3, 1.02U
2.2 !pidural anal5esia not
routinely available
; &pontaneous va5inal birth
1=
2088 $is@ $atio BI, 4i>ed, =6H CI
$is@ $atio BI, 4i>ed, =6H CI
1.02 0.=;, 1.11U
&ubtotals only;.1 !pidural anal5esia
routinely available
1; 1282 $is@ $atio BI, 4i>ed, =6H CI 1.0 1.01, 1.08U
;.2 !pidural anal5esia not
routinely available
Caesarean birth
8
22
168 $is@ $atio BI, 4i>ed, =6H CI
$is@ $atio BI, 4i>ed, =6H CI
1.11 1.08, 1.1U
&ubtotals only
.1 !pidural anal5esia
routinely available
1 1;08 $is@ $atio BI, 4i>ed, =6H CI 0.=; 0.38, 1.02U
7/26/2019 cochranedatabasesystrev.doc
84/170
.2 !pidural anal5esia not
routinely available
20 $is@ $atio BI, 4i>ed, =6H CI 0.6 0.;, 0.83U
7/26/2019 cochranedatabasesystrev.doc
85/170
.; +n@nown availability of
epidural anal5esia
6 "dmission to special care nursery
1
; $is@ $atio BI, 4i>ed, =6H CI
$is@ $atio BI, 4i>ed, =6H CI
1. 0.1, 1;.=3U
&ubtotals only
6.1 !pidural anal5esia
routinely available
6 3;30 $is@ $atio BI, 4i>ed, =6H CI 0.=3 0.36, 1.1;U
6.2 !pidural anal5esia not
routinely available
8 'ostpartum depression
2
2
61 $is@ $atio BI, 4i>ed, =6H CI
$is@ $atio BI, 4i>ed, =6H CI
0.28 0.03, 0.33U
&ubtotals only
8.1 !pidural anal5esia
routinely available
1 8=16 $is@ $atio BI, 4i>ed, =6H CI 0.3= 0.6, 1.06U
8.2 !pidural anal5esia not
routinely available
1 1= $is@ $atio BI, 4i>ed, =6H CI 0.13 0.0=, 0.;8U
)e5ative ratin5 of/ne5ative
feelin5s about birth e>perience
11 $is@ $atio BI, 4i>ed, =6H CI &ubtotals only
.1 !pidural anal5esia
routinely available
= 100 $is@ $atio BI, 4i>ed, =6H CI 0.0 0.8, 0.U
.2 !pidural anal5esia not
routinely available
2 $is@ $atio BI, 4i>ed, =6H CI 0.66 0.3, 0.8;U
3 %reastfeedin5 at 1ed, =6H CI &ubtotals only
3.1 !pidural anal5esia
routinely available
2 621 $is@ $atio BI, 4i>ed, =6H CI 0.== 0.=6, 1.0;U
3.2 !pidural anal5esia not
routinely available
1 1= $is@ $atio BI, 4i>ed, =6H CI 1.16 0.=6, 1.0U
Comarison 8/ Continuous suort versus usual $are % oli$y a#out routine E6*
.o/ of .o/ of'ut$ome or su#grou title studies arti$iants Statisti$al met)od Effe$t sie
1 "ny anal5esia/anaesthesia 1 $is@ $atio BI, 4i>ed, =6H CI &ubtotals only
1.1 &ettin5 had routine !4 8 3630 $is@ $atio BI, 4i>ed, =6H CI 0.= 0.=8, 0.==U
1.2 &ettin5 did not have
routine !4
8 2138 $is@ $atio BI, 4i>ed, =6H CI 0.=8 0.=0, 1.02U
1.; 'olicy about routine !4
not @nown
2 &ynthetic o>ytocin durin5 labour
2
16
16= $is@ $atio BI, 4i>ed, =6H CI
$is@ $atio BI, 4i>ed, =6H CI
0.3= 0.30, 0.==U
&ubtotals only
2.1 &ettin5 had routine !4 3;0 $is@ $atio BI, 4i>ed, =6H CI 1.0 0.=3, 1.11U
2.2 &ettin5 did not have
routine !4
128 $is@ $atio BI, 4i>ed, =6H CI 0.== 0.=8, 1.01U
2.; 'olicy about routine !4
not @nown
; &pontaneous va5inal birth
1=
2683 $is@ $atio BI, 4i>ed, =6H CI
$is@ $atio BI, 4i>ed, =6H CI
1.02 0.=, 1.03U
&ubtotals only
;.1 &ettin5 had routine !4 3 =1 $is@ $atio BI, 4i>ed, =6H CI 1.0; 1.01, 1.08U
;.2 &ettin5 did not have
routine !4
1=1; $is@ $atio BI, 4i>ed, =6H CI 1.11 1.08, 1.1U
7/26/2019 cochranedatabasesystrev.doc
86/170
;.; 'olicy about routine !4
not @nown
Caesarean birth
22
2681 $is@ $atio BI, 4i>ed, =6H CI
$is@ $atio BI, 4i>ed, =6H CI
1.0 1.01, 1.1;U
&ubtotals only
7/26/2019 cochranedatabasesystrev.doc
87/170
.1 &ettin5 had routine !4 = 1012; $is@ $atio BI, 4i>ed, =6H CI 0.=2 0.3;, 1.01U
.2 &ettin5 did not have
routine !4
3 26 $is@ $atio BI, 4i>ed, =6H CI 0.88 0.66, 0.=U
.; 'olicy about routine !4
not @nown
6 "dmission to special care nursery
6
26=6 $is@ $atio BI, 4i>ed, =6H CI
$is@ $atio BI, 4i>ed, =6H CI
1.08 0.3, 1.;;U
&ubtotals only6.1 &ettin5 had routine !4 ; 0 $is@ $atio BI, 4i>ed, =6H CI 0.= 0.3, 1.11U
6.2 &ettin5 did not have
routine !4
; 2= $is@ $atio BI, 4i>ed, =6H CI 0.3 0.21, 1.12U
6.; 'olicy about routine !4
not @nown
8 'ostpartum depression
1
2
23 $is@ $atio BI, 4i>ed, =6H CI
$is@ $atio BI, 4i>ed, =6H CI
1.=3 0.8, 6.13U
&ubtotals only
8.1 &ettin5 had routine !4 1 8=16 $is@ $atio BI, 4i>ed, =6H CI 0.3= 0.6, 1.06U
8.2 &ettin5 did not have
routine !4
1 1= $is@ $atio BI, 4i>ed, =6H CI 0.13 0.0=, 0.;8U
)e5ative ratin5 of/ne5ativeviews
about birth e>perience
.1 &ettin5 had routine !4
11
8
$is@ $atio BI, 4i>ed, =6H CI
$is@ $atio BI, 4i>ed, =6H CI
&ubtotals only
0.8 0.80, 0.8U
.2 &ettin5 did not haveroutine !4
110 $is@ $atio BI, 4i>ed, =6H CI 0.80 0.6;, 0.83U
.; 'olicy about routine !4
not @nown
; 1= $is@ $atio BI, 4i>ed, =6H CI 0.3 0.86, 1.03U
3 %reastfeedin5 at 1ed, =6H CI
$is@ $atio BI, 4i>ed, =6H CI
&ubtotals only
0.= 0.=2, 1.02U
3.2 &ettin5 did not have
routine !4
2 30 $is@ $atio BI, 4i>ed, =6H CI 1.06 0.=3, 1.1;U
Comarison ;/ Continuous suort versus usual $are % variations in rovider $)ara$teristi$s
.o/ of .o/ of'ut$ome or su#grou title studies arti$iants Statisti$al met)od Effe$t sie
1 "ny anal5esia/anaesthesia 1 $is@ $atio BI, 4i>ed, =6H CI &ubtotals only
1.1 &upport people were
hospital staff
8 =162 $is@ $atio BI, 4i>ed, =6H CI 0.= 0.=8, 0.==U
1.2 &upportpeople were not
hospital staff and not chosen
by woman
1=0 $is@ $atio BI, 4i>ed, =6H CI 0.=1 0.38, 0.=U
1.; &upportpeople were not
hospital staff and were chosen
by woman
2 &ynthetic o>ytocin durin5 labour
16
103 $is@ $atio BI, 4i>ed, =6H CI
$is@ $atio BI, 4i>ed, =6H CI
0.= 0.33, 1.00U
&ubtotals only
2.1 &upport people were
hospital staff
8 =681 $is@ $atio BI, 4i>ed, =6H CI 1.08 1.01, 1.11U
7/26/2019 cochranedatabasesystrev.doc
88/170
2.2 &upportpeople were not
hospital staff and not chosen
by woman
; 1013 $is@ $atio BI, 4i>ed, =6H CI 0.8= 0.60, 0.=U
7/26/2019 cochranedatabasesystrev.doc
89/170
2.; &upportpeople were not
hospital staff and were chosen
by woman
; &pontaneous va5inal birth
8
1=
201 $is@ $atio BI, 4i>ed, =6H CI
$is@ $atio BI, 4i>ed, =6H CI
0.== 0.=8, 1.01U
&ubtotals only
;.1 &upport people were
hospital staff
= 1031; $is@ $atio BI, 4i>ed, =6H CI 1.0; 1.01, 1.08U
;.2 &upportpeople were not
hospital staff and were chosen
by woman
6 10 $is@ $atio BI, 4i>ed, =6H CI 1.0 0.==, 1.16U
;.; &upportpeople were not
hospital staff and not chosen
by woman
Caesarean birth
6
22
1=;6 $is@ $atio BI, 4i>ed, =6H CI
$is@ $atio BI, 4i>ed, =6H CI
1.12 1.0, 1.1U
&ubtotals only
.1 &upport people were
hospital staff
= 1038 $is@ $atio BI, 4i>ed, =6H CI 0.=6 0.36, 1.06U
.2 &upportpeople were not
hospital staff and not chosen
by woman
2;;0 $is@ $atio BI, 4i>ed, =6H CI 0.2 0.80, 0.38U
.; &upportpeople were nothospital staff and were chosen
by woman
6 "dmission to special care nursery
8
206= $is@ $atio BI, 4i>ed, =6H CI
$is@ $atio BI, 4i>ed, =6H CI
0.3; 0.8=, 1.01U
&ubtotals only
6.1 &upport people were
hospital staff
; 23 $is@ $atio BI, 4i>ed, =6H CI 0.== 0.3, 1.1U
6.2 &upportpeople were not
hospital staff and not chosen
by woman
2 32= $is@ $atio BI, 4i>ed, =6H CI 0.38 0.88, 1.12U
6.; &upportpeople were not
hospital staff and were chosen
by woman
8 'ostpartum depression
2
2
80 $is@ $atio BI, 4i>ed, =6H CI
$is@ $atio BI, 4i>ed, =6H CI
1.0 0.8, 2.=;U
&ubtotals only
8.1 &upport people were
hospital staff
1 668 $is@ $atio BI, 4i>ed, =6H CI 0.38 0.;, 1.02U
8.2 &upportpeople were not
hospital staff and not chosen
by woman
1 1= $is@ $atio BI, 4i>ed, =6H CI 0.1 0.0=, 0.;;U
8.; &upportpeople were not
hospital staff and were chosen
by woman
0 0 $is@ $atio BI, 4i>ed, =6H CI 0.0 0.0, 0.0U
)e5ative ratin5 of/ne5ative
feelin5s about birth e>perience
11 $is@ $atio BI, 4i>ed, =6H CI &ubtotals only
.1 &upport people were
hospital staff
316 $is@ $atio BI, 4i>ed, =6H CI 0.3 0.;, 1.0;U
.2 &upportpeople were nothospital staff and not chosen
by woman
; 1;26 $is@ $atio BI, 4i>ed, =6H CI 0.88 0.6, 0.U
.; &upportpeople were not
hospital staff and were chosen
by woman
103 $is@ $atio BI, 4i>ed, =6H CI 0.6 0.61, 0.8U
3 %reastfeedin5 at 1ed, =6H CI &ubtotals only
postpartum
7/26/2019 cochranedatabasesystrev.doc
90/170
7/26/2019 cochranedatabasesystrev.doc
91/170
3.1 &upport people
were hospital staff
1 66= $is@ $atio BI, 4i>ed, =6H CI 0.= 0.=2, 1.02U
3.2 &upportpeople were not
hospital staff and not chosen
by woman
2 30 $is@ $atio BI, 4i>ed, =6H CI 1.06 0.=3, 1.1;U
3.; &upportpeople were not
hospital staff and were chosen
by woman
0 0 $is@ $atio BI, 4i>ed, =6H CI 0.0 0.0, 0.0U
nalysis 11 Comparison 1 Continuous support versus usual care ? all
trials& +utcome 1 ny analgesiaanaesthesia
Review: Continuous support for women during childbirth
Comparison: 1 Continuous support versus usual care - all trials
Outcome: 1 Any analgesia/anaesthesia
tudy or subgroup Continuous support
!sual care Ris"Ratio
#eight Ris" Ratio$-
n/% n/%&'Random'()*
C+&'Random'()*
$orhason-,ello ..( 0/( (/( )21 * .2(0 3 .24' 121
Campbell ..6 04/(1 6./() 12( * .2(6 3 .2(.' 12.
&odnett .. .44/0)0 1)(/061 1)24 * .2( 3 .2(6' .2((
$adi 1((( /) 01/)6 2( * .24 3 .2)' .2(4
7anger 1(( ()/61 ./6 124 * .2( 3 .2(' 12.)
8agnon 1((4 101/.( 10/.0 1.2. * .2(4 3 .2)' 121.
,reart - ,elgium ))/1 6/1 026 * .2) 3 .26)' 121
,reart - 9rance 1(( 1/6) 1(/666 1.24 * .2(. 3 .2.' 12.1
&ofmeyr 1((1 )/( )6/(4 )2 * .2( 3 .246' 12)
ennell 1((1 (/1 1)./.. 42( * .2) 3 .20(' .26(
&emmin"i 1((.a )/01 / 2. * 12.1 3 .241' 1200
&emmin"i 1((.b 0)/1 )/. )2. * .2) 3 .266' 121.
;uenyong .1 1/) 1)/)6 12. * .20 3 .200' 126.
laus 1(6 /16 1./0( .2 * .2. 3 .2.4' 120
>otal 3; CIF 953< 92@+2 ?4)*
7/26/2019 cochranedatabasesystrev.doc
92/170
nalysis 12 Comparison 1 Continuous support versus usual care ? all trials&
+utcome 2 Regional analgesiaanaesthesia
Review: Continuous support for women during childbirth
Comparison: 1 Continuous support versus usual care - all trials
Outcome: Regional analgesia/anaesthesia
tudy or subgroup Continuous support
!sual care Ris"Ratio
#eight Ris" Ratio$-
n/% n/%&'Random'()*
C+&'Random'()*
$c8rath .. 10)/0 10(/1(6 1.2 * .2) 3 .24)' .2(6
Campbell ..6 04/(1 6./() 1026 * .2(6 3 .2(.' 12.
&odnett .. 0(/0)0 06/061 1626 * .2(4 3 .2(0' 12..
otal 3; CIF ;747 ;727 255/5 5/3: [ 5/@+2 ?1*
7/26/2019 cochranedatabasesystrev.doc
93/170
nalysis 1: Comparison 1 Continuous support versus usual care ? all trials& +utcome :
%ynthetic o7ytocin during labour
Review: Continuous support for women during childbirth
Comparison: 1 Continuous support versus usual care - all trials
Outcome: ynthetic oDytocin during labour
tudy or subgroup Continuous support
!sual care Ris"Ratio
#eight Ris" Ratio$-
n/% n/%&'Random'()*
C+&'Random'()*
,reart - ,elgium ))/1 60/1( 024 * .20 3 .260' 121.
,reart - 9rance 1(( /6)0 41/666 121 * 12.) 3 .2(6' 121)
,reart - 8reece 0/4 1(/6) 12. * 12.4 3 .2(4' 121
,ruggemann ..4 1.0/1.) 1.4/1.4 1421 * .2(( 3 .2(6' 12.
Campbell ..6 1/(1 100/() 2 * .2(0 3 .24(' 1211
8agnon 1((4 /.( (6/.0 621 * .2 3 .264' 12.0
&odnett .. 1.0./0)0 (0/061 1020 * 1211 3 12.' 121(
&ofmeyr 1((1 16/( 14/(4 121 * .2(( 3 .2)' 12)
ashanian .1. 11/). 1(/). 121 * .2) 3 .21' 12.(
ennell 1((1 6/1 06/.. 26 * .240 3 .2).' 12.(
laus 1(6 0/16 4/0( .20 * .216 3 .2.6' .200
$adi 1((( 4/) 14/)6 .24 * .200 3 .2.' .2(6
$orhason-,ello ..( )1/( )6/( 2 * .2(1 3 .260' 12
otal 3; CIF 947; 9:8; 255/5 5/37 [ 5/32, 2/58 ]
' (( =!sual care>
&eterogeneity:
7/26/2019 cochranedatabasesystrev.doc
94/170
nalysis 1; Comparison 1 Continuous support versus usual care ? all trials& +utcome; 'abour length
Review: Continuous support for women during childbirth
Comparison: 1 Continuous support versus usual care - all trials
Outcome: 0 7abour length
tudy or subgroup Continuous support!sual care
$eanEifference#eight
$eanEifference
% $ean=E> % $ean=E> +F'Random'()*C++F'Random'()*C+
$orhason-,ello ..( ( 024 =124> ( )2 =124> 1(20 *
-.26. 3 -.2' -.2 5 Campbell ..6 (1 1.20 =02> () 1124 =02>
26 * -12. 3 -2.0' -.2)6 5 8agnon 1((4 .( (21 =021> .0 (20 =024>
421 * -.2. 3 -121)' .2)) 5 ,reart - ,elgium 1(( 1 624 =)24> 1( 62 =02.4>
02) * -.2) 3 -126' .26 5 ,reart - 9rance 1(( 6)0 6244 =2)4> 666 42.4 =26>
1(2 * -.2. 3 -.2)' -.2. 5 ,reart - 8reece 1(( 4 6264 =24)> 6) 62 =2(>
1.2 * .20 3 -.2.' .2( 5 ennell 1((1 1 420 =2> .. 20 =02>
21 * -12.. 3 -1244' -.2 5 &ofmeyr 1((1 ( (26 =2(> (4 1.2 =02(>
2 * -.26. 3 -124' .264 5 7anger 1(( 61 02)6 =204> 6 )2) =204>
121 * -12. 3 -12)' -.2)1 5 &emmin"i 1((.a 0 2 =62> 1 1. =62>
.24 * -124. 3 -024' 1204 5 ;uenyong .1 ) 112 =)26> 0) 120 =42>
.2( * -.266 3 -20.' 2. 5 &emmin"i 1((.b 1 )21 =2> . )24 =24>
020 * -.26. 3 -1246' .2)6 5
>otal 3; CIF 4933 4997 255/5 %5/;< [ %5/
7/26/2019 cochranedatabasesystrev.doc
95/170
=1
Copyright 2012 The Cochrane Collaboration !ublished by "ohn #iley $ %ons& 'td
7/26/2019 cochranedatabasesystrev.doc
96/170
nalysis 1
&eterogeneity:
7/26/2019 cochranedatabasesystrev.doc
97/170
nalysis 1= Comparison 1 Continuous support versus usual care ? all trials&
+utcome = .nstrumental vaginal birth
Review: Continuous support for women during childbirth
Comparison: 1 Continuous support versus usual care - all trials
Outcome: 6 +nstrumental vaginal birth
tudy or subgroup Continuous
su
!sual
car
Ris" Ratio
$-&'9iDed'()* C+
Ris" Ratio
$-&'9iDed'()* C+
ashanian .1. ./). ./) .2. 3 .2.'
,ruggemann ..4 )/1.) )4/1.4 .2() 3 .24'
Campbell ..6 1/(1 /() .26. 3 .21'
&odnett .. )01/0)0 )61/061 .2(4 3 .24'
Eic"inson .. 10/0(( 16(/0( .24 3 .24'
$adi 1((( /) (/) .2 3 .2.)'
otal 3; CIF 754< 7535 5/35 [ 5/@+2 ?)*
7/26/2019 cochranedatabasesystrev.doc
98/170
nalysis 1> Comparison 1 Continuous support versus usual care ? all trials& +utcome >Caesarean birth
Review: Continuous support for women during childbirth
Comparison: 1 Continuous support versus usual care - all trials
Outcome: 4 Caesarean birth
tudy or subgroup Continuous support
!sual care Ris"Ratio
#eight Ris" Ratio$-
n/% n/%&'Random'()*
C+&'Random'()*
ashanian .1. 0/). 1/). 12 * .2 3 .21' .2(6
$orhason-,ello ..( 4/.) 6/( 62 * .2( 3 .26' .2)(
$c8rath .. ./0 0(/1(6 620 * .2)0 3 .2)' .21
,ruggemann ..4 11/1.) 1/1.4 2( * .2( 3 .20' 2.
Campbell ..6 ))/(1 )/() 420 * 12.) 3 .24)' 120
&odnett .. 0/0)0 04/061 112. * .2(( 3 .24' 121
Eic"inson .. 41/0(( )/0( 2 * .2 3 .26' 121.
$adi 1((( /) 4/) 12 * .20) 3 .21' 1266
&eterogeneity:
7/26/2019 cochranedatabasesystrev.doc
99/170
nalysis 1D Comparison 1 Continuous support versus usual care ? all trials& +utcome D!erineal trauma
Review: Continuous support for women during
childbirth Comparison: 1 Continuous support
versus usual care - all trials Outcome: erineal
trauma
tudy or subgroup Continuous support !sual care Ris"Ratio
#eight Ris" Ratio$-
n/% n/%&'Random'()*
C+&'Random'()*
,ruggemann (0/1.) ()/1. 1621 * 12.1 3 .2(' 1211
&odnett .. 1/0)0 16./061 42. * .2( 3 .2(0' 12.
Campbell ..6 0(/(1 4)/() .2. * .2( 3 .24' .2(4
8agnon 1((4 16/.4 166/.. 162( * .2( 3 .2(' 12.4
>otal 3; CIF 85;7 859: 255/5 5/37 [ 5/34, 2/52 ]
' (6 =!sual care>
&eterogeneity:
7/26/2019 cochranedatabasesystrev.doc
100/170
nalysis 1E Comparison 1 Continuous support versus usual care ? all trials&+utcome E 'ow
7/26/2019 cochranedatabasesystrev.doc
101/170
nalysis 110 Comparison 1 Continuous support versus usual care ? all trials&
+utcome 10 dmission to special care nursery
Review: Continuous support for women during childbirth
Comparison: 1 Continuous support versus usual care - all trials
Outcome: 1. Admission to special care nursery
tudy or subgroup Continuous support !sual care Ris"Ratio
Ris" Ratio$-
n/% n/%&'Random'()*
C+&'Random'()*
ashanian .1. ./). ./). .2. 3 .2.' .2. 5
,ruggemann ..4 )/1.) 6/1.4 .2) 3 .24' 24.
&odnett .. 06/0)0 )0/061 .2(4 3 .2' 121)
otal 3; CIF 882: 88@+2 ?4*
Copyright 2012 The Cochrane Collaboration !ublished by "ohn #iley $ %ons& 'td
7/26/2019 cochranedatabasesystrev.doc
102/170
nalysis 111 Comparison 1 Continuous support versus usual care ? all trials&
+utcome 11 !rolonged neonatal hospital stay
Review: Continuous support for women during childbirth
Comparison: 1 Continuous support versus usual care - all trials
Outcome: 11 rolonged neonatal hospital stay
tudy or subgroup Continuous support !sual care Ris"Ratio
Ris" Ratio$-
n/% n/%&'Random'()*
C+&'Random'()*
ashanian .1. ./). ./) .2. 3 .2.' .2. 5
Campbell ..6 14/(1 10/() 12 3 .26' 20)
ennell 1((1 /1 0/.. .261 3 .24' 12.1
>otal 3; CIF ;;: ;8; 5/@+2 ?6*
7/26/2019 cochranedatabasesystrev.doc
103/170
nalysis 112 Comparison 1 Continuous support versus usual care ? all trials&
+utcome 12 !ostpartum report of severe labour pain
Review: Continuous support for women during childbirth
Comparison: 1 Continuous support versus usual care - all trials
Outcome: 1 ostpartum report of severe labour pain
tudy or subgroup Continuous support
!sual care Ris"Ratio
#eight Ris" Ratio$-
n/% n/%&'Random'()*
C+&'Random'()*
7anger 1(( 61/)6 0/) 121 * 12.0 3 .2()' 1210
,reart - ,elgium 61/11( )/11 .2 * 1214 3 .2(.' 12)
,reart - 9rance 1(( 1)4/6)6 1(/660 020 * 1210 3 .2(' 120.
&ofmeyr 1((1 )/( 46/(6 02 * .24 3 .2)(' .2(
>otal 3; CIF 244: 24:: 255/5 2/55 [ 5/@+2 ?4*
7/26/2019 cochranedatabasesystrev.doc
104/170
nalysis 11: Comparison 1 Continuous support versus usual care ? all trials& +utcome
1: -egative rating ofnegative feelings about birth
e7perience
Review: Continuous support for women during childbirth
Comparison: 1 Continuous support versus usual care - all trials
Outcome: 1 %egative rating of/negative feelings about birth eDperience
tudy or subgroup Continuous support
!sual care Ris"Ratio
#eight Ris" Ratio$-
n/% n/%&'Random'()*
C+&'Random'()*
$orhason-,ello ..( 1./( 1(6/( 120 * .2)) 3 .206' .26)
,ruggemann ..4 4/1.) 14/1.4 2) * .20 3 .21' .2(4
Campbell ..6 ()/( 1(4/6) 120 * .2)6 3 .204' .266
&odnett .. (6/1 114/4)1 1.2) * .2. 3 .261' 12.0
Eic"inson .. 4)/0(( 40/0( (24 * 12.. 3 .240' 12)
otal 3; CIF ;;@+2 ?6*
0Copyright 2012 The Cochrane Collaboration !ublished by "ohn #iley $ %ons& 'td
7/26/2019 cochranedatabasesystrev.doc
105/170
nalysis 11; Comparison 1 Continuous support versus usual care ? all trials&
+utcome 1; 4ifficulty mothering
Review: Continuous support for women during childbirth
Comparison: 1 Continuous support versus usual care - all trials
Outcome: 10 EiGculty mothering
tudy or subgroup Continuous support !sual care Ris" Ratio Ris"
n/% n/% $-&'9iDed'()* C+ $-&'9iDed'()*
Campbell ..6 11/( /6) .26 3 .210'
&odnett .. 4/6 )/46) 12.. 3 .2('
&ofmeyr 1((1 01/4) 64/4) .261 3 .20('
.21 .2 .2) 1 ) 1.
9avours support 9avours usual care
nalysis 11
&eterogeneity:
7/26/2019 cochranedatabasesystrev.doc
106/170
Copyright 2012 The Cochrane Collaboration !ublished by "ohn #iley $ %ons& 'td
7/26/2019 cochranedatabasesystrev.doc
107/170
nalysis 11= Comparison 1 Continuous support versus usual care ? all trials&
+utcome 1= !ostpartum depression
Review: Continuous support for women during childbirth
Comparison: 1 Continuous support versus usual care - all trials
Outcome: 16 ostpartum depression
tudy or subgroup Continuous support !sual care Ris" Ratio Ris"
&odnett ..
n/%
0)/16
n/%
44/4)1
$-&'9iDed'()* C+ $-&'9iDed'()*C+
&ofmeyr 1((1 /40 00/4 .21 3 .2.('
.2) .24 1 12)
9avours support 9avoursusual care
Continuous support for women during childbirth (Review)>2
Copyright 2012 The Cochrane Collaboration !ublished by "ohn #iley $ %ons& 'td
7/26/2019 cochranedatabasesystrev.doc
108/170
nalysis 11> Comparison 1 Continuous support versus usual care ? all trials& +utcome
1> 'ow postpartum self?esteem
Review: Continuous support for women during childbirth
Comparison: 1 Continuous support versus usual care - all trials
Outcome: 14 7ow postpartum self-esteem
tudy or subgroup Continuous support !sual care Ris" Ratio #eight Ris"
7anger 1((
n/%
)/6
n/%
./1
$-&'9iDed'()* C+
1..2. *
$-&'9iDed'()*C+
>otal 3; CIF ::9 :29 255/5 2/55 [ 5/77, 2/:5 ]
' . =!sual care>
&eterogeneity: not applicable
:
Copyright 2012 The Cochrane Collaboration !ublished by "ohn #iley $ %ons& 'td
7/26/2019 cochranedatabasesystrev.doc
109/170
nalysis 21 Comparison 2 Continuous support versus usual care ? policy regarding
presence of companion& +utcome 1 ny
analgesiaanaesthesia
Review: Continuous support for women during childbirth
Comparison: Continuous support versus usual care - policy regarding presence of companion
Outcome: 1 Any analgesia/anaesthesia
tudy or subgroup Continuous
su
!sual
car
Ris" Ratio
+F'9iDed'()* C+
#eight Ris"Ratio
1 Other supportpermitted
04/.. 6./.. 024 * .2() 3 .2('
&odnett .. .44/0)0 1)(/061 (126 * .2( 3 .2(6'
8agnon 1((4 101/.( 10/.0 12 * .2(4 3 .2)'
,reart - ,elgium ))/1 6/1 .2 * .24 3 .264'
,reart - 9rance 1(( 1/6)6 1(/660 126 * .2( 3 .24('
&emmin"i 1((.a )/01 / .2 * 12.1 3 .241'
&emmin"i 1((.b 0)/1 )/ .2 * .2) 3 .266'
Su#total 3; CIF 8@+2 ?.2.*
Other support not permitted
$orhason-,ello ..( 0/( (/( )26 *
.2(0 3 .24' 121 5 $adi 1((( /) 01/)6
2( * .24 3 .2)' .2(4 5 7anger 1(( ()/61 ./6
4421 * .2( 3 .2(' 12.) 5 &ofmeyr 1((1 11/( 1)/(4
.24 * .244 3 .24' 12)( 5 ;uenyong .1 1/) 1)/)6
.2 * .20 3 .200' 126. 5 ennell 1((1 (/1 1)./..
112 * .2) 3 .20(' .26( 5 laus 1(6 /16 1./4(
.2 * .2. 3 .2.4' 12) 5
Su#total 3; CIF 24;; 2:8: 255/5 5/32 [ 5/@+2 ?*
;
Copyright 2012 The Cochrane Collaboration !ublished by "ohn #iley $ %ons& 'td
7/26/2019 cochranedatabasesystrev.doc
110/170
nalysis 22 Comparison 2 Continuous support versus usual care ? policy regarding
presence of companion& +utcome 2 %ynthetic o7ytocin during
labour
Review: Continuous support for women during childbirth
Comparison: Continuous support versus usual care - policy regarding presence of companion
Outcome: ynthetic oDytocin during labour
tudy or subgroup Continuous
su
!sual
car
Ris" Ratio
+F'9iDed'()* C+
#eight Ris"Ratio
1 Other supportpermitted
Campbell ..61/(1 100/() (20 * .2(0 3 .24('
1211 5&odnett .. 1.0./0)0 (0/061 0(24 * 1211 3 12.'
8agnon 1((4 /.( (6/.0 )2) * .2 3 .264'
,reart - ,elgium1((
))/1 60/1( 2( * .20 3 .260'121. 5
,reart - 9rance 1(( /6)0 41/666 12) * 12.) 3 .2(6'
Su#total 3; CIF 8785 87;; 255/5 2/58 [ 5/33, 2/25 ]
' 1614=!sual care>
&eterogeneity: Chi2 ? 1.24' df ? 0 = ?
.2.>@+2 ?61*
Other suppor t notpermitted
ashanian .1. 11/). 1(/). .21 *
.2) 3 .21' 12.( 5 $orhason-,ello ..( )1/( )6/(
.2) * .2(1 3 .260' 12 5 ,ruggemann ..4 1.0/1.) 1.4/1.4
621 * .2(( 3 .2(6' 12. 5 $adi 1((( 4/) 14/)6
.21 * .200 3 .2.' .2(6 5@+2 ?60*
7/26/2019 cochranedatabasesystrev.doc
111/170
Continuous support for women during childbirth (Review)>@+2 ?0*
Other support not permitted
ashanian .1. 06/). /). ) 121 3 12.'
,ruggemann ..4 01/1.) /1.4 1 121. 3 .24'
$adi 1((( 0/) 0./)6 0 124 3 12.)'
.2) .24 1 12)
9avours usual 9avours
BContinued. . .
Continuous support for women during childbirth (Review)>=
Copyright 2012 The Cochrane Collaboration !ublished by "ohn #iley $ %ons& 'td
7/26/2019 cochranedatabasesystrev.doc
113/170
B. . . Continuedtudy or subgroup Continuous suppor !sual care Ris" Ratio #eigh Ris"
n/% n/% +F'9iDed'()* C+ +F'9iDed'()*
&eterogeneity: Chi2 ? 1214' df ? ( = ? .2.>@+2 ?6*
7/26/2019 cochranedatabasesystrev.doc
114/170
B. . . Continuedtudy or subgroup Continuous suppor !sual care Ris" Ratio #eigh Ris"
n/% n/% +F'9iDed'()* C+ +F'9iDed'()*
&eterogeneity: Chi2 ? 112)' df ? 1. = ?
.2(>@+2 ?16*
Other support not permitted
ashanian .1. 0/). 1/). 12( *
.2 3 .21' .2(6 5 $orhason-,ello ..( 4/.) 6/(
12 * .2( 3 .26' .2)( 5 ,ruggemann ..4 11/1.) 1/1.4
2) * .2( 3 .20' 2. 5 $adi 1((( /) 4/)6
12 * .20) 3 .21' 1266 5 &eterogeneity: Chi2 ? 6211' df ?
1. = ? .2..0>@+2 ?6*
D
Copyright 2012 The Cochrane Collaboration !ublished by "ohn #iley $ %ons& 'td
7/26/2019 cochranedatabasesystrev.doc
115/170
nalysis 2@+2 ?*
Other suppor t notpermitted
ashanian .1. ./). ./).
.2. 3 .2.' .2. 5 ,ruggemann ..4 )/1.) 6/1.4
.2) 3 .24' 24. 5 &eterogeneity: Chi2 ? 626.' df ?
= ? .2.(>@ +2 ?))*
7/26/2019 cochranedatabasesystrev.doc
116/170
Continuous support for women during childbirth (Review)>E
Copyright 2012 The Cochrane Collaboration !ublished by "ohn #iley $ %ons& 'td
7/26/2019 cochranedatabasesystrev.doc
117/170
nalysis 2= Comparison 2 Continuous support versus usual care ? policy regarding
presence of companion& +utcome = !ostpartum depression
Review: Continuous support for women during childbirth
Comparison: Continuous support versus usual care - policy regarding presence of companion
Outcome: 6 ostpartum depression
tudy or subgroup Continuous
su
!sual
car
Ris" Ratio
+F'9iDed'()* C+
#eight Ris"Ratio
1 Other supportpermitted
0)/16 44/4)1 1..2. * .26 3 .24'
Su#total 3; CIF 4' +2 ?()*
.2) .24 1 12)
9avours support 9avoursusual care
Continuous support for women during childbirth (Review)D0
Copyright 2012 The Cochrane Collaboration !ublished by "ohn #iley $ %ons& 'td
7/26/2019 cochranedatabasesystrev.doc
118/170
nalysis 2> Comparison 2 Continuous support versus usual care ? policy regarding
presence of companion& +utcome > -egative rating ofnegative feelings
about birth e7perience
Review: Continuous support for women during childbirth
Comparison: Continuous support versus usual care - policy regarding presence of companion
Outcome: 4 %egative rating of/negative feelings about birth eDperience
tudy or subgroup Continuous
su
!sual
car
Ris" Ratio
+F'9iDed'()* C+
#eight Ris"Ratio
1 Other support
Campbell ..6 ()/( 1(4/6) ).2 * .2)6 3 .204'
&odnett .. (6/1 114/4)1 .26 * .2. 3 .261'
Eic"inson .. 4)/0(( 40/0( 162) * 12.. 3 .240'
,reart - ,elgium 0/1 ./11 62 * .24( 3 .20('
,reart - 9rance 1(( ./6)6 )/660 620 * .24 3 .2)0'
Su#total 3; CIF 8::; 8:58 255/5 5/75 [ 5/94, 5/7< ]
' 0) =!sual care>
&eterogeneity: Chi2 ? 102).' df ? 0 = ?
.2.1>@+2 ?4*
Other support not permitted
$orhason-,ello ..( 1./( 1(6/( (24 *
.2)) 3 .206' .26) 5 ,ruggemann ..4 4/1.) 14/1.4
126 * .20 3 .21' .2(4 5@+2 ?0)*
7/26/2019 cochranedatabasesystrev.doc
119/170
nalysis 2D Comparison 2 Continuous support versus usual care ? policy regarding
presence of companion& +utcome D reastfeeding at 1?2 months
postpartum
Review: Continuous support for women during childbirth
Comparison: Continuous support versus usual care - policy regarding presence of companion
Outcome: ,reastfeeding at 1- months postpartum
tudy or subgroup Continuous
su
!sual
car
Ris" Ratio
+F'9iDed'()* C+
#eight Ris"Ratio
1 Other supportpermitted
11/( 1/. 1..2. * .2(4 3 .2('
Su#total 3; CIF 4::3 4445 255/5 5/37 [ 5/34, 2/54 ]
' 1 =!sual care>
&eterogeneity: not applicable
Other support not permitted
&ofmeyr 1((1 )/40 )1/4) 102) *
121) 3 .2()' 120. 5 7anger 1(( 66/0 04/1
)2) * 12.0 3 .2()' 121 5
Su#total 3; CIF 85< :39 255/5 2/5; [ 5/3@+2 ?.2.*
7/26/2019 cochranedatabasesystrev.doc
120/170
nalysis :1 Comparison : Continuous support versus usual care ? availability of
epidural analgesia& +utcome 1 ny
analgesiaanaesthesia
Review: Continuous support for women during childbirth
Comparison: Continuous support versus usual care - availability of epidural analgesia
Outcome: 1 Any analgesia/anaesthesia
tudy or subgroup Continuous
su
!sual
car
Ris" Ratio
+F'9iDed'()* C+
#eight Ris"Ratio
1 Hpidural analgesia routinely available
&emmin"i 1((.a )/01 / .2 * 12.1 3 .241'
ennell 1((1 (/1 1)./.. .24 * .2) 3 .20('
&emmin"i 1((.b 0)/1 )/. .2 * .2) 3 .266'
8agnon 1((4 101/.( 10/.0 12 * .2(4 3 .2)'
7anger 1(( ()/61 ./6 026 * .2( 3 .2('
,reart - 9rance 1(( 1/6)6 1(/660 12) * .2( 3 .24('
,reart - ,elgium1((
))/1 6/11 .2 * .24 3 .264'121) 5
&odnett .. .44/0)0 1)(/061 624 * .2( 3 .2(6'
Campbell ..6 04/.. 6./.. 02) * .2() 3 .2('
Su#total 3; CIF ;887 ;882 255/5 E 5/37 [ 5/39, 5/3< ]
' 006( =!sual care>
&eterogeneity: Chi2 ? 42' df ?
=B.2....1>@+2 ?4(*
Hpidural analgesia not routinely available
$adi 1((( /) 01/)6 )2. *
.24 3 .2)' .2(4 5 $orhason-,ello ..( 0/( (/(
).21 * .2(0 3 .24' 121 5 laus 1(6 /16 1./4(
120 * .2. 3 .2.4' 12) 5 &ofmeyr 1((1 11/( 1)/(4
62. * .244 3 .24' 12)( 5 ;uenyong .1 1/) 1)/)6
42) * .20 3 .200' 126. 5
Su#total 3; CIF 9@+2 ?.2.*
7/26/2019 cochranedatabasesystrev.doc
121/170
D:
Copyright 2012 The Cochrane Collaboration !ublished by "ohn #iley $ %ons& 'td
7/26/2019 cochranedatabasesystrev.doc
122/170
tudy or subgroup Continuous support !sual care Ris" Ratio #eight Ris
n/% n/% +F'9iDed'()* C+ +F'9iDed
Hpidural analgesia routinely available
nalysis :2 Com