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Comparative hospital performance: new data, borrowed methods, more targeted analysis?
Professor Jonathan Karnon
Why do we measure hospital performance?
1. To ‘sack the Board’ Aggregate, or aggregated performance measure Under direct control of those being assessed
– Costs OR Process indicators Not so interested in magnitude of difference
– Identify general poor performance
2. To inform target areas for quality improvement Condition-specific Not necessarily under direct control
– Costs, outcomes, and processes Value of improvement important
Task: Improve population
health
Option 1: Fund new
technologies
Option 2: Improve use of
existing technologies
Show me the money
Increasing interest in quality improvement
1983 1988 1993 1998 2003 2008 20130
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500
600
Year
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Not a new idea
“a programme of work not only to identify causes of variation at specific local level, but also to prioritise those variations and causes that have the most important impact on equity, effectiveness, efficiency and patient health outcomes”?
Variations in health care: The good, the bad and the inexplicable, The King’s Fund 2011
Outline
Evidence of variation; The information: costs, outcomes, and processes The incentives: potential strategies for using the information
Variation in process
RAND Corp (McGlynn et al, NEJM 2003)– 30 acute and chronic conditions and preventive care– 10 to 80% participants receiving recommended care
CareTrack (Runciman et al, MJA 2012)– 22 common conditions– 32 to 86% compliance with appropriate care
Variation in costs
Duckett & Breadon, Controlling costly care: a billion-dollar hospital opportunity, Grattan Institute 2014
$ per admission (2010/11)
Variation in outcomes
*adjusted by age, sex, indigenous origin and Diagnostic Group Hierarchical Condition Category (HCC) risk score
30-Day Readmission Rates by Area Health Service of Residence (NSW: 1 July 2005 – 30 June 2008)*
Policy/Practice Relevance?
Appropriate processes in theory ≈ cost-effective care in practice? – Costs? Timeliness?
Best outcomes? – Meaningful outcomes? At what cost?
Lowest cost? – With what outcomes?
Which providers are providing cost-effective care, and how are they doing it?
Using comparative condition-specific health service data
Systematic review– Feedback of comparative performance data alone does not work
Anecdotal– Service change works best when common recognition of a problem
Theory– Costs and post-discharge outcomes data demonstrates problems
Despite risk adjustment ‘my patients are sicker’ syndrome– Process data provides
Additional rationale for the existence of a problem Starting points for identifying solutions
11
Case study: ED chest pain presentations
Four public hospital in South Australia Clinical context, underlying diagnosis could be:
– ST Elevated MI– Non-ST Elevated MI – Unstable angina– Non-cardiac chest pain
Aims:– Identify benchmark performer(s) on basis of costs and outcomes– Assess the potential value of improved performance at non-
benchmark hospitals– Inform targets for investigation – variation in clinical pathways
12
The data
Clinical data extracted from common data warehouse– key procedures, pathology test results, movement between hospital
departments and wards, etc. – automated linkages to population-based mortality data.
Administrative data, linked to index events to identify other inpatient separation (episodes) at all South Australian hospitals– age, gender, and postcode (SEIFA), co-morbidities
13
Missing data
ED capacity– ED beds, personnel– Other presentations: rates and severity
Inpatient capacity– Bed occupancy rates
Cardiac Non-cardiac
– Staffing ratios
14
The dependent variables
Costs: Bottom-up patient-level costs available for all inpatient separations
Outcomes: 30 day/12 month related admission (unstable angina, MI, or stroke) or mortality
Process, not quality indicators– Pr(admission)– Time to admission– Pr(PCI | angiogram)– Inpatient LoS
15
The analysis
Separate multiple regression models fitted – Cost, outcome, and process variables
Hospital interaction terms tested – Identify patient sub-groups driving variation
Mean covariate values used to generate predicted outputs – Bootstrapping, stratified by hospital, to represent uncertainty
16
Patient characteristics
Hospital 1 Hospital 2 Hospital 3 Hospital 4 Difference (p value)
No. patients 1997 1527 2368 2058Age 60.2 62.5 59.1 57.9 <0.001Male 0.54 0.53 0.53 0.54 0.768SEIFA decile 5.4 4.0 6.0 2.6 <0.001Positive troponin test result 0.17 0.13 0.12 0.11 <0.001Existing circulatory disorder 0.37 0.33 0.37 0.33 0.002Cancer 0.03 0.03 0.03 0.02 0.189COPD 0.03 0.03 0.03 0.03 0.706Renal disease 0.07 0.08 0.09 0.07 0.398Diabetes 0.07 0.06 0.09 0.10 <0.001Dementia/Alzheimer's 0.01 0.02 0.01 0.01 0.716After hours presentation 0.61 0.62 0.59 0.58 0.082Weekend presentation 0.24 0.25 0.23 0.24 0.636
17
SEIFA – SocioEconomic Indicator For Areas: 1=lowest decile
Inpatient costs per presenting patient
Sub-group N Hosp 4 Hosp 1 - Hosp 4 Hosp 2 - Hosp 4 Hosp 3 - Hosp 4
All patients 7950 $2,868 $42 $630($307 to $989)
$510($299 to $713)
Existing circ., Out-of-hours 1706 $4,539 $229 $1,542
($786 to $2365)$510
($299 to $713)
No existing circ., Out-of-hours 1082 $1,579 -$451 $136
(-$73 to $361)$510
($299 to $713)
Existing circ., In-hours 3050 $4,640 $643 $1,265
($513 to $2111)$510
($299 to $713)
No existing circ., In-hours 2112 $1,610 -$6 -$91
(-$318 to $143)$510
($299 to $713)
NHosp 1 Hosp 2 Hosp 3 Hosp 4
Pr(event) RR (95%CI)
12m readmission or death
All patients 7950 0.045 1.59(1.27 - 1.93)
1.06(0.80 - 1.35)
1.16(0.91 - 1.47)
Young males 2281 0.043 1.59(1.27 - 1.94)
1.09(0.75 - 1.51)
1.16(0.91 - 1.47)
Old males 1979 0.102 1.54(1.25 - 1.85)
1.50(1.18 - 1.93)
1.14(0.91 - 1.43)
Young females 1701 0.025 1.61
(1.28 - 1.97)0.76
(0.47 - 1.20)1.16
(0.90 - 1.48)
Old females 1989 0.086 1.55(1.26 - 1.87)
1.09(0.81 - 1.42)
1.15(0.91 - 1.44)
12m mortality
All patients 7950 0.02 1.42 (0.93 to 2.05)
0.82 (0.47 to 1.23)
1.05 (0.83 to 1.2)
12m readmission
All patients 7950 0.03 1.72 (1.27 to 2.27)
1.22 (0.84 to 1.66)
1.30 (1.01 to 1.92)
C-E Acceptability Planes
value_avoiding_death_000s0.00
value_avoiding_readmission_000s
50.00
prho
sp_3
_cos
t_ef
fect
ive
100.000.00
50.00
100.00
0.00
0.17
0.35
value_avoiding_death_000s0.00
value_avoiding_readmission_000s
50.00
prho
sp_1
_cos
t_ef
fect
ive
100.000.00
50.00
100.00
0.02
0.39
0.76
value_avoiding_death_000s0.00
value_avoiding_readmission_000s
50.00
prho
sp_4
_cos
t_ef
fect
ive
100.000.00
50.00
100.00
0.16
0.56
0.97
value_avoiding_death_000s0.00
value_avoiding_readmission_000s
50.00
prho
sp_2
_cos
t_ef
fect
ive
100.000.00
50.00
100.00
0.00
0.01
0.03
Pr(Admitted)
NHospital 1 Hospital 2 Hospital 3 Hospital 4
Pr(admitted) RR (95%CI)
All patients 7950 0.77 0.87 (0.83 - 0.91)
0.92 (0.89 - 0.96)
0.92 (0.88 - 0.96)
Troponin +ive, Existing circulatory condition 842 0.97 0.99
(0.98 - 1.01)0.97
(0.94 - 0.99)0.97
(0.94 - 0.99)Troponin +ive, No existing circulatory condition
216 0.87 0.88 (0.79 - 0.95)
0.89 (0.78 - 0.97)
0.89 (0.78 - 0.97)
Troponin -ive, Existing circulatory condition 1946 0.89 0.98
(0.94 - 1.03)0.97
(0.95 - 0.99)0.97
(0.94 - 0.99)Troponin -ive, No Existing circulatory condition
4946 0.62 0.71 (0.65 - 0.77)
0.90 (0.84 - 0.96)
0.90 (0.83 - 0.96)
21
Pr(PCI | Angiogram)
22
NHospital 1 Hospital 2 Hospital 3 Hospital 4
Pr() RR (95%CI)
All patients 7950 0.14 2.40 (1.71 - 3.36)
1.79 (1.31 - 2.44)
1.57 (1.14 - 2.15)
Troponin +ive, Weekend 279 0.30 2.18
(1.36 - 3.44)1.07
(0.62 - 1.87)0.94
(0.54 - 1.53)Troponin +ive, Weekday 779 0.22 2.03
(1.44 - 2.79)1.22
(0.83 - 1.74)1.72
(1.26 - 2.28)Troponin -ive, Weekend 1632 0.17 2.76
(1.48 - 4.74)1.72
(0.96 - 2.93)0.93
(0.49 - 1.64)Troponin -ive, Weekday 5260 0.12 2.36
(1.56 - 3.41)2.02
(1.35 - 2.92)1.90
(1.32 - 2.64)
Length of Stay as inpatient
23
N Hosp4 (hrs) Hosp1 - Hosp4 Hosp2 - Hosp4 Hosp3 - Hosp4
All patients 5373 37.2 7.4(4.46 - 10.32)
4.5(0.79 - 8.38)
10.5(7.58 - 13.42)
Troponin +ive, Out-hours presentation 561 56.4 3.3
(-7.28 - 14.39)18.0
(2.52 - 34.19)16.3
(5.84 - 27.24)
Troponin +ive, In-hours presentation 325 51.1 7.0
(-3.44 - 17.45)13.8
(-1.55 - 29.42)15.2
(4.33 - 26.11)
Troponin -ive, Out-hours presentation 2702 33.8 6.5
(3.29 - 9.52)3.8
(-0.13 - 7.87)9.9
(6.50 - 13.03)
Troponin -ive, In-hours presentation 1785 35.3 10.2
(5.88 - 14.53)-0.4
(-5.02 - 4.19)8.7
(4.76 - 12.46)
How to compare larger numbers of providers?
Stratify by clinical process and identify best performing strata?– Hypothesis driven?– Process mining driven?
Group hospitals by performance and compare processes?– Empirical stratification
Informing action
“Publicising the existence of unwarranted variations and their causes does not guarantee that they will be tackled.”
“local health organisations… be required to publicly justify and explain in a consistent way their relative position on key aspects of health care variation.
…it may also be necessary to explore the development of harder-edged, locally focused incentives to encourage action to deal with unwarranted variation.”
Variations in health care: The good, the bad and the inexplicable, The King’s Fund 2011
The incentives
26
1. Sticksa) Public Reportingb) Mandated action plans
2. Carrotsa) Pay-for-Performance?b) External Services Improvement Fund
Mindful of the NHS Improvement Fund…
1b + 2b– Externally identified areas for improvement– Externally reviewed and supported applications to fund improvement
projects
Prioritisation criteria
27
Expected Value of Removing Variation (EVRV)– Hospital 2, 1527 patients per annum– Costs per patient could reduce by $630– Mortality could decrease by 1% (x $200,000?)– Readmissions decrease by 2% (x $50,000?)
Annual EVRV = 1527 x $(630 + 2000 + 1000) = $5.5 million x5? x10?
Zombies and Paradoxes
• “political paradox of rationing”
• “the appeal for transparency in medical decision-making is like a zombie, an idea that refuses to die despite its limited utility”
• Do the benefits of open and explicit quality improvement outweigh the: Financial costs and Political risks of unrealistic expectations?
Oberlander et al, Rationing medical care: rhetoric and reality in the Oregon Health Plan, CMAJ, 2001; 164(11):1583-7
Summary
29
Huge scope for service evaluation and improvement– Electronic data systems– Linkage facilities
Post-improvement evaluation: ICER estimates to inform the– Design of future improvement processes– Balance of spending on new technologies and existing services
Acknowledgements
Clarabelle Pham, Andrew Partington, Orla Caffrey, Jason Gordon, Brenton Hordacre, David Ben-Tovim, Paul Hakendorf, Maria Crotty
Funders: SA Health, NHMRC, HCF Foundation