Accelerating Research to Improve Health

What is CTSI?

• Cross-school, UCSF-wide institute with scientist leaders at its helm

• Provides infrastructure, services and training to support clinical and translational research

What is CTSI?, continued

• Develops broad coalitions and partnerships locally and nationally to enable a transformation of the research environment

CTSI Quick Facts

• Established in 2006

• 200+ faculty collaborated on successful NIH proposal

• Supports all 4 UCSF schools

• Received 5-year renewal award in 2011 (second largest institute of its kind nationwide)

National Reach

• CTSI is among the first of the60-member, NIH-funded CTSA awards consortium

Affiliates

CTSI achieves its mission by working with a range of institutions across the Bay Area:

•Children's Hospital Oakland Research Institute

•Kaiser Foundation Research Institute

•Kaiser Permanente Division of Research

Affiliates, continued

• California Institute for Quantitative Biosciences (QB3)

• San Francisco Veterans Affairs Medical Center

• J. David Gladstone Institutes

Affiliates, continued

• Ernest Gallo Clinic and Research Center

• Blood Systems Research Institute

• Jewish Home of San Francisco

• San Francisco Dept. of Public Health

CTSI ’06-’10 Achievements

• Supported the clinical research of1,500+ researchers from UCSF and affiliates – Includes wide-ranging resources across 8 Bay Area clinical

research sites

• Provided UCSF investigators with 22,000+ hours of expert consultations since 2006– Service areas range from biostatistics to research ethics

CTSI ’06-’10 Achievements, cont.

• Launched UCSF Profiles– Online networking and collaboration tool that enables

the discovery of research expertise at UCSF

• Created the UCSF Participant Recruitment Service – Helps researchers find and enroll participants in UCSF

clinical studies

CTSI ’06-’10 Achievements, cont.

• Awarded $4.5+ millionin pilot awards– Proportionally distributed across

UCSF’s 4 schools

• Established SF Bay HIP– SF Bay Health Improvement Program brings together

diverse community partners with the goal of creating measurable improvements in health in the Bay Area

CTSI ’06-’10 Achievements, cont.

• 28:1 ROI on initiative to advance multi-site clinical studies– In an impact study on one of CTSI’s small grants programs,

an investment of $485,000 resulted in $14 million in new research funding for UCSF

• 100% increase in competitive career development grants for faculty scholars

CTSI ’06-’10 Achievements, cont.

• Initiated the T1 Catalyst Award– Provides pilot funding and extensive consultations to

accelerate the development of commercially viable treatments and diagnostics

• Increased the proportion of budget recovered through revenue by50+ percent