DEVELOPING SOLUTIONS FOR BRAZILIAN SUBSTRATESThomas RasmussenManager of R&D Brazil

Novozymes' R&D locations

LEADING THE WAY IN ENABLING TECHNOLOGY FOR CONVERTING BIOMASS TO SUGAR TO FUELS AND TO CHEMICALS World leader in biofuel enzymes More than 180 researchers dedicated Only Industrial Biotech Company with R&D center in Brazil

BRAZILIAN FEEDSTOCKS

Sorghum

Sugar beet

Energy cane

EucalyptusWhen compared to corn stover, the pretreated Brazilian substrates:

• Are often more recalcitrant• Are often more crystalline• Have often higher lignin content

A significant challenge

Sugarcane

DEVELOPING A SOLUTION FOR BRAZILIAN SUBSTRATES

CTec4 - Bagasse

0 1 2 3 4 5 6 7 8 9 100%

10%20%30%40%50%60%70%80%

0 5 100%

10%20%30%40%50%60%70%80%

Gluo

se y

ield

(%)

0 1 2 3 4 5 6 7 8 9 100%

10%20%30%40%50%60%70%80%

2009Novozymes Cellic® CTec2 on BagasseBagasse seemed indestructible

Enzyme dosage (mg P/gC)

Data: 72 h, 12% TS

2012Commercial CTec3It is possible to reach same conversion of PCB vs PCS

Bagasse (PCB) Corn Stover(PCS)

Pre-commercial version of CTec3Large improvement with CTec3 (GH61) and 2 step pre-treatment

2011

Starch

Cellulose

Sugar

Enzymetechno-

logy

Enzymetechno-

logy

Bio-ethanol

Bio-chemicals

Pre-treatment

Metabolicpathway

engineering enables

higher yields & new

products

Enzymeproduc-

tion

USING BIOTECHNOLOGY TO PRODUCE BIOCHEMICALS FROM SUGAR-BASED PLATFORMS

Petro-based

feedstock

Fermen-tablesugar

Chemicals (bulk, fine, specialty)

Enzyme techno-

logy

Fermen-tation

Advanced fermen-tation

Chemical catalysis

Enzyme techno-

logy

Market potential• Market size: USD 114.1 billion (2010)• Market volume: 76,964 kMT/year (2010)• Annual growth: 6%• Applications: Car bumpers, plastic

containers, drinking straws, toys Source : SRI Consulting

Price-competitive alternativeThe project goal is to be cost-competitive compared to petrochemical routes.

Produced from renewables

Source: SRI Consulting

Petro-based feedstock Polypropylene

Sugar cane Polypropylene

Strain development and piloting Demonstration of technology Commercial scale production

2010 2015 2020

NOVOZYMES’ BIOCHEMICALS PROJECT:GREEN POLYPROPYLENE WITH BRASKEM

Price in USD 2000 2010

Propylene 530/MT 1200/MT

Partnering strategy to be re-evaluated in the

demonstration phase

ADVANCED BIOFUEL IS ONLY THE BEGINNING TOWARDS A BIO-ECONOMY

THANK YOU

Join us!www.bioenergy.novozymes.com