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1 DHS Chemical Terrorism Risk Assessment and Desktop Tool Bethesda, MD - April 29, 2014 George R. Famini Jessica A. Cox Rachel E. Gooding U.S.A Department of Homeland Security Chemical Security Analysis Center Aberdeen Proving Ground, MD Presenter’s Name June 17, 2003 2 Chemical Security Analysis Center CSAC provides analysis and scientific assessment of the chemical threat against the American homeland and American public. Integration and Analysis of Chemical Threat Information and Data Reachback Capability to Provide Expert Analysis Support Fusion of Information from Different Communities Chemical Hazard Awareness, Assessment and Analysis Science-Based Risk Assessment Basic Science Chemical Industry Intelligence Community Operational Requirements CSAC Presenter’s Name June 17, 2003 DHS Risk Assessments 3 Are end-to-end assessments focused on a broad range of risks incorporating hazards, emerging technologies, available countermeasures and IC/ LE input to evaluate the acute risk to human health due to a chemical biological, radiological or nuclear attack on the U.S. Homeland. Mandated by HSPD-18, Medical Countermeasures against Weapons of Mass Destructions, and HSPD-22, Domestic Chemical Defense. Provides 3 primary outputs needed to examine risk mitigation strategies Critical Vulnerabilities Critical Data/Knowledge Gaps Relative Risk Ranking of compounds, targets, classes of compounds, scenario, etc. Targeted studies put useable information inot the hands of the end users Scenario driven strategies Local/Regional Risk Many Others
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  • 1

    DHS Chemical Terrorism Risk Assessment and Desktop Tool

    Bethesda, MD - April 29, 2014

    George R. Famini Jessica A. Cox Rachel E. Gooding U.S.A Department of Homeland Security Chemical Security Analysis Center Aberdeen Proving Ground, MD

    Presenter’s Name June 17, 2003 2

    Chemical Security Analysis Center CSAC provides analysis and scientific assessment of the chemical threat against the American homeland and American public.

    •  Integration and Analysis of Chemical Threat Information and Data

    §  Reachback Capability to Provide Expert Analysis Support

    §  Fusion of Information from Different Communities

    §  Chemical Hazard Awareness, Assessment and Analysis

    §  Science-Based Risk Assessment

    Basic Science

    Chemical Industry

    Intelligence Community

    Operational Requirements

    CSAC

    Presenter’s Name June 17, 2003

    DHS Risk Assessments

    3

    •  Are end-to-end assessments focused on a broad range of risks incorporating hazards, emerging technologies, available countermeasures and IC/LE input to evaluate the acute risk to human health due to a chemical biological, radiological or nuclear attack on the U.S. Homeland.

    •  Mandated by HSPD-18, Medical Countermeasures against Weapons of Mass Destructions, and HSPD-22, Domestic Chemical Defense.

    •  Provides 3 primary outputs needed to examine risk mitigation strategies

    •  Critical Vulnerabilities •  Critical Data/Knowledge Gaps •  Relative Risk Ranking of compounds, targets,

    classes of compounds, scenario, etc.

    •  Targeted studies put useable information inot the hands of the end users

    •  Scenario driven strategies •  Local/Regional Risk •  Many Others

  • 2

    Presenter’s Name June 17, 2003

    Critical Components of the CTRA

    4

    Each section represents a significant data collection/generation effort. Input data obtained through interagency coordination.

    Presenter’s Name June 17, 2003

    2012 CTRA Compound List

    5

    Presenter’s Name June 17, 2003

    2012 CTRA Toxidromes

    6

    A particular toxidrome can be identified with clinical observations including vital signs, mental status, mucous membrane irritation, lung exam for wheezing or rales, skin for burns, moisture, and color. For CSAC purposes, the toxidromes include:

    Toxidrome Chemical Examples Upper Pulmonary Allyl alcohol, Hydrogen fluoride, Nitric oxide Lower Pulmonary Benzene thiol, Chlorine, Phosgene Vesicant Lewisite, Nitrogen mustard, Sulfur Mustard Blood Acrylonitrile, Methanethiol, Cyanides Hemolytic/Metabolic Arsine, Carbon disulfide Anticoagulant Brodificoum, Bromodialone, Diphacinone Convulsants Picrotoxin, Strychnine, TETS Cholinergic CWA Cyclosarin, Soman, VX Cholinergic Other Aldicarb, Disulfoton, Parathion, Phorate Opioid Carfentanil, Diacetylmorphine

  • 3

    Presenter’s Name June 17, 2003

    2012 CTRA Target Classes & Targets

    7

    Presenter’s Name June 17, 2003

    CTRA Event Tree

    8

    Event 3

    Event N

    Event 1

    Event 2

    Scen

    ario

    1

    Scen

    ario

    2

    Scen

    ario

    N

    •  CTRA scenarios are defined by an event tree •  Provides a framework for generating a more

    than a billion representative attack scenarios from a distribution of relative frequencies for each branch, and it considers interdependencies among events

    •  Each branch encounters the next decision point (event level), and one of several subsequent courses of action (branches)

    •  The complete event tree contains multiple events, each having branches that represent different choices or outcomes

    •  A path through the event tree is a CTRA scenario. The likelihood of the various branches at each level are sampled from distributions.

    •  The probabilities of each branch along a path through the tree are multiplied to get the scenario probability

    Presenter’s Name June 17, 2003

    2012 CTRA Modeling Overview

    9

    Dermal

    Fail

    Exposed

    Candidates for Treatment

    Appropriate End-State

    Symptomatic

    Expo

    sure

    Sym

    ptom

    Ons

    et

    Dead

    Alive, Saved

    Alive, Not Benefited

    Alive, Benefited

    Worried Well

    Multipliers

    Succeed

    Available Countermeasures

    Primary Altern. #1 Altern. #2

    Countermeasure Deployment

    Gen

    eral

    Pop

    ulat

    ion

    Col

    loca

    te w

    / Med

    ical

    Per

    sonn

    el

    Access to Medical Care

    Exam

    or D

    econ

    tam

    inat

    ion

    Exposed Seeking Care

    Next Tier

    Adm

    inis

    ter T

    reat

    men

    t

    Worry Time

    Death

    Severe

    Worried Well

    Life-threat.

    Severe

    Mild/Mod.

    Life-threat.

    Severe

    Mild/Mod.

    Life-threat.

    Severe

    Mild/Mod.

    Life-threat.

    Worried Well

    Mild/Mod.

    Worried Well

    Exit / Restriction

    Appropriate End-State

    Local Regional National

    Countermeasure Stockpiles

    Medical Mitigation

    SurroundingPopulation

    Exposure  Footprint

    HPAC  Batching

    Look-‐Up  TablesLocation

    0.0

    0.5

    1.0

    1.5

    2.0

    2.5

    0.00.5

    1.0

    1.5

    2.0

    2.5

    0.00.5

    1.01.5

    2.02.5

    Z

    X

    Y

    Meteorology

    Scenario-‐Specific  Source  Term

    HPAC  Input

    GISBased

    HPACBased

    GISBased

    HPACBased

    Illness or Injury

    Consumption Consumer Storage

    Retail Storage

    Storage at the Processing Plant and Distribution

    PackagingProcessing

    Storage,Separation, Ingredients,

    Homogenization, Pasteurization

    Farm Tank

    Consumer Preparation

    Output Storage

    Recall and Consumer

    Announcements

    Tanker Truck

    Food Indoor

    Water

    Outdoor

  • 4

    Presenter’s Name June 17, 2003

    Inhalation Modeling- Outdoor

    10

    SurroundingPopulation

    Exposure  Footprint

    HPAC  Batching

    Look-‐Up  TablesLocation

    0.0

    0.5

    1.0

    1.5

    2.0

    2.5

    0.00.5

    1.0

    1.5

    2.0

    2.5

    0.00.5

    1.01.5

    2.02.5

    Z

    X

    Y

    Meteorology

    Scenario-‐Specific  Source  Term

    HPAC  Input

    GISBased

    HPACBased

    GISBased

    HPACBased

    HPAC dispersion, overlaid on a GIS-based population model at GIS land tag informed locations

    Presenter’s Name June 17, 2003

    Synthesis of Multiple Data Sets

    11

    Time resolved contour overlays

    A B C D E F G

    0 FREQUENCY

    0.8 LOW

    2.3 MED

    4.1 HIGH

    6.7

    9.6

    12

    Wind  Spee

    d  (m

    /s)

    Stability  Class

    Provides a comprehensive synthesis and application of location, meteorology and population density for use in risk analysis.

    HSIP Gold ISHD from NCDC

    •  HSIP Gold – Homeland Security Information Program

    •  CHIRP – Chemical Hazard information retrieval portal

    •  ISHD – Integrated Surface Hourly Data •  NCDC – National Climatic Data Center

    Presenter’s Name June 17, 2003

    Indoor Inhalation Modeling

    12

    o  Well-mixed zonal model (CONTAM equivalent) integrated with moving population

    o  Models a release zone, near zone, and far zone; and either recirculated air between the zones or within a single zone. There is a separate model developed for subways.

    o  Each building type has area and population boundaries. For example, The Pentagon, Sears Tower, Empire State Building, Chrysler Building, and Transamerica Building

    o  Awareness in the Inhalation Models begins after a weighted number of symptomatic victims is generated by the model.

    •  Based on chemical concentration, toxicity, and exposure duration •  Considers scenario timing, evacuation time is target dependent •  Model output is the number of injured victims and their exposure terms

  • 5

    Presenter’s Name June 17, 2003

    Three Zone Model

    13

    •  Numerical solution •  Assumes building is not well-

    mixed –  3 well-mixed zones:

    •  Release zone •  Near zone •  Far zone

    •  There are two versions of the three zone model –  Recirculated air between

    zones –  Recirculated air within a

    single zone •  Separate model developed for

    subways •  Comparison for high fidelity 100 zone model was very favorable

    1

    2

    Presenter’s Name June 17, 2003

    Ingestion Modeling- Food

    14

    Illness or Injury

    Consumption Consumer Storage

    Retail Storage

    Storage at the Processing Plant and Distribution

    PackagingProcessing

    Storage,Separation, Ingredients,

    Homogenization, Pasteurization

    Farm Tank

    Consumer Preparation

    Output Storage

    Recall and Consumer

    Announcements

    Tanker Truck

    Stock-and-Flow model incorporating

    • food processing and distribution • chemical stability; • recalls and timing

    Expanded food clusters representing thousands of foods

    Presenter’s Name June 17, 2003

    Representative Food Clusters

    15

    •  The National Center for Food Protection and Defense (NCFPD) and the CSAC Decision Analysis Team (DAT) performed a cluster analysis using a binary scoring system of food and food process characteristics to identify a set of clusters representative of the food supply chain

    •  An exemplar food and contamination point(s) from each cluster were then selected by SMEs from the food industry and academia as a representative scenario for that portion of the food industry

    Multi-component assembled foods, thermally processed in the home

    Multi-component assembled foods, not thermally processed in the home

    Packaged, processed, cold chain RTE Ready-to-eat, primary component foods

    Assembled companion dishes Main dishes, single component foods

    Beverages Produce Home ingredients Industrial ingredients

  • 6

    Presenter’s Name June 17, 2003

    Food Recall Model Components

    16

    Investigation

    Information Diffusion

    Compliance

    Investigation initiated due to a cluster of Illnesses

    Recall issued for a specific product

    Recall Timeline

    Presenter’s Name June 17, 2003

    Ingestion Modeling- Water

    17

    • Notional Water distribution network model built based on characteristics from 3 city specific distribution networks • Compares favorably against EPAnet results from 2 different cities

    Presenter’s Name June 17, 2003

    Dermal Modeling

    18

    Custom-built model, validated against PTA/MTA scenarios Incorporates: Hand size Transfer efficiency Absorption

  • 7

    Presenter’s Name June 17, 2003

    Medical Mitigation Modeling

    19

    Stock and Flow modeling simulates the progression and time sensitive nature of the response

    •  Predicts number of mild to moderate, severe, and life threatening injuries. •  Victims can be exposed at different times •  Accounts for treatment rate limits and burden of worried well and minor injuries •  Different victims can progress at different rates •  First victims initiate response that may save later victims •  Tiered and alternative treatments •  Allows for situational awareness •  The size of the attack can trigger release of additional resources and victim prioritization •  Example model parameters include:

    •  time to treatment identification •  efficacy of treatment •  countermeasure dosage •  countermeasure quantities •  time for countermeasures to arrive

    •  time for symptom onset •  co-location time •  time to die •  time for symptom mitigation •  decontamination time

    Presenter’s Name June 17, 2003

    Medical Mitigation Modeling

    20

    Fail

    Exposed

    Candidates for Treatment

    Symptomatic

    Expo

    sure

    Sym

    ptom

    Ons

    et

    Dead

    Alive, Saved

    Alive, Not Benefited

    Alive, Benefited Worried

    Well Multipliers

    Succeed

    Available Countermeasures

    Primary Altern. #1

    Altern.

    #2

    Countermeasure Deployment

    Gen

    eral

    Pop

    ulat

    ion

    Col

    loca

    te w

    / Med

    ical

    Per

    sonn

    el

    Access to Medical Care

    Exam

    or D

    econ

    tam

    inat

    ion

    Next Tier

    Adm

    inis

    ter T

    reat

    men

    t

    Worry Time

    Severe

    Worried Well

    Life- threat.

    Severe

    Mild/ Moderate

    Life- threat.

    Severe

    Mild/ Moderate

    Life- threat.

    Severe

    Mild/ Moderate

    Life- threat.

    Worried Well

    Mild/ Moderate

    Worried Well

    Local Regional National Countermeasure Stockpiles

    Outcome Exposed Symptomatic Treatment Attack

    End State

    Presenter’s Name June 17, 2003

    •  The medical response is parameterized •  The response is divided into a series of discrete events; each

    discrete event corresponds to a quantifiable model parameter •  Medical toxicology and emergency medicine SME’s were

    enlisted to quantify model parameters and inform model methodology

    •  The SME’s were tasked to review and improve data-based values and estimate/extrapolate from literature as necessary

    •  Medical response is based on Toxidrome (10 toxidromes) •  A single simulation of the response to a chemical attack can involve

    over 100 parameter values •  Example model parameters:

    Modeling Approach

    21

    •  time to treatment identification •  efficacy of treatment •  countermeasure dosage •  countermeasure quantities •  time for countermeasures to arrive

    •  time for symptom onset •  co-location time •  time to die •  time for symptom mitigation •  decontamination time

  • 8

    Presenter’s Name June 17, 2003

    §  A combination of models and data drive the CTRA §  The best data are mined from existing sources and through

    extensive interaction with SME’s §  Models are continually reviewed and refined, if necessary, to

    provide the best possible estimates within the constraints of the project §  Industry standard models are used to validate against §  Stakeholder input and feedback are valued and used as drivers

    for improvement §  Comparison with existing assessments, such as PTA/MTA’s

    are performed for benchmarking

    CTRA Modeling Summary

    22

    Presenter’s Name June 17, 2003

    CTRA Desktop Tool

    23

    -  Driven by Stakeholder needs CSAC has developed a desktop tool to produce quicker response time, create a parameter screening tool and allow focused follow-up risk studies

    -  Existing consequence models and data from 2012 CTRA are incorporated into an easy to use platform

    -  Real time calculations can be performed outside the parameter space considered in CTRA enhancing flexibility and allowing very specific questions to be answered.

    -  Millisecond run time per simulation

    Examples: •  What is the impact of

    evacuation time in the DC subway during a CK release?

    •  What is impact if a subset of navigable waterway routes are used for a particular chemical?

    Presenter’s Name June 17, 2003

    CTRA Desktop Tool

    24

    Chemical Terrorism Risk Assessment

    Transform into a flexible and fast consequence analysis tool Standard Laptop Enhanced Capability

    • Intuitive • “Explore the Edges” • Beta version ready for transition to customers

    Requested by CSAC’s customers and stakeholders

  • 9

    Presenter’s Name June 17, 2003

    Permits Detailed Analysis

    25

    Different Locations •  Indoor •  Outdoor •  Food •  Dermal •  Water

    Various Mitigation Strategies •  Detectors •  Enhanced Evacuation •  Shelter in Place •  Modifications to HVAC •  Medical CMs •  Collective Protection •  Individual Protection

    And Explore the Effects of:

    •  Explores the impact of various chemical, device, detection or response parameters

    •  Tests the impact of various modeling assumptions and data estimates

    Presenter’s Name June 17, 2003

    Arena Example

    26

    Attack Scenario Mass [kg]

    Exposed Population (gray)

    Life Threatening injuries (red) Severe Injuries (blue) P

    eopl

    e

    10,000 Simulations showing the range of life threatening injuries Mean life threatening injuries: 313±522

    Presenter’s Name June 17, 2003

    Arena Example- Countermeasures Consumed

    27

    Num

    ber o

    f CM

    Life Threatening Injuries

    Atropine

    Ventilators

  • 10

    Presenter’s Name June 17, 2003

    How Can the Results Be Used?

    28

    •  Public health and fatality risk may be obtained by chemical, by target, by toxidrome, or any modeled result and depicted in a variety of ways (whisker plot, probability vs. consequence, scatter plot, pie, bar) to help aid policymakers and develop strategies.

    •  Detailed analysis helps to understand the risk. •  Is it driven by consequences or frequency? Weighted Average Consequences per

    Attack (WACPA) or Frequency of Successful Attack (FOSA) for table top exercises

    •  CSC scenarios can be segregated by commodity, availability or chemical class to aid in planning and preparedness

    •  Input parameters/assumptions can be tested. Observations of results can drive research, operations and planning

    •  Sensitivity of risk can be analyzed and weighted: o  Detection o  Security or mitigation o  Medical response

    Presenter’s Name June 17, 2003

    CSC- Mean Risk by Target

    29

    -  Identify key risk drivers by target/chemical combination to help refine strategies

    Target 1

    Target 2

    Target 3

    Target 4

    Target 5

    Target 6

    Mean Public Health Risk by Target Mean Fatality Risk by Target

    Presenter’s Name June 17, 2003

    Notional Results

    30

    • Understanding of risk drivers-consequence or frequency • Appreciation of uncertainty and expected range

    Narrow uncertainty in consequences, significant uncertainty in frequency

  • 11

    Presenter’s Name June 17, 2003

    Notional Results

    31

    Understanding of main contributors to overall risk will guide strategy in buying down risk Inventory control is very different than securing facility assets

    Presenter’s Name June 17, 2003

    Notional Results

    32

    Chemical

    Rel

    ativ

    e R

    isk

    Basic Security and Mitigation Advanced Security and Mitigation

    Chemical

    Rel

    ativ

    e R

    isk

    §  Sensitivity studies §  Impact of security and mitigation posture §  Estimate of the impact of CFATS–like regulation comparing the risk of

    facilities from pre- and post-9/11 environments

    Presenter’s Name June 17, 2003

    §  It is the first end-to-end probabilistic risk assessment that is all inclusive and provides a detailed look at the entire chemical risk space including threat, vulnerability and consequences.

    §  The risk assessment provides: §  Relative risk ranking of chemicals, targets, toxidromes, etc

    §  Provides focus and allows resources to be prioritized based on quantitative risk

    §  Parsing of the main contributor to risk by chemical, targets, toxidromes, etc. §  Provides the ability to determine data/knowledge gaps as well as

    sensitivities in which risk may be able to be reduced §  Prediction of impact of a vast array of scenarios

    §  Provides the ability to vary pre-event measures (e.g. security posture, forward placement and stockpiling of medical countermeasures) and post-event responses (mitigation, medical response) to determine impact

    §  Allows pre-operational decisions to be made based on risk.

    What is the Value of the CTRA?

    33

  • 12

    Presenter’s Name June 17, 2003

    •  CTRA –  Three iterations completed; 2008, 2010 and 2012 –  2012 completed in February 2012 –  Assesses 125 representative chemicals, 37

    representative targets –  Major upgrade to food, water & med mit methodologies

    •  Desktop Calculator –  Specifically requested by stakeholders –  Currently focused on consequences, but incorporation

    of risk is planned –  Has been used to address 35 specific questions

    regarding chemical attacks

    •  Tailored Assessments –  Detailed analysis of “what if” scenarios –  35 tailored assessments have been completed and 5

    more are underway or are planned –  Meet stakeholder requests & assist them to fulfill their

    mission requirements, provide operational guidance & make risk informed decisions.

    CTRA Accomplishments

    34

    Presenter’s Name June 17, 2003

    §  Valuable tools for assessing Public Health risk from a terrorist attack

    §  Three primary outputs 1.  Critical Vulnerabilities 2.  Critical Data Gaps 3.  Intelligence informed relative risk-based ranking and

    consequences of compounds, targets and scenarios for a wide range of chemical threats

    §  Numerous secondary outputs (Tailored Assessments/Sensitivity Studies)

    Together these products allow decision makers and risk managers to inform policy and examine risk mitigation strategies from terrorism risk and impact

    What the CTRA Provides

    35

    Presenter’s Name June 17, 2003

    Access to CSAC Information

    36

    Jessica Cox [email protected]

    202-658-8221

    Rachel Gooding [email protected]

    410-436-0018

    Lars Skinner [email protected]

    410-436-5969

    Reachback (24/7/365) •  [email protected] •  410-417-0910

    HSDN Website •  http://www.dhs.sgov.gov/csac • All published reports/presentations

    for download

    Unclassified Webpage under construction

    HSIN & HSLIC Webpage •  FOUO documents only • Bulletins/reports shared with state

    and local authorities

  • 13


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