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Diagnostic serology hepatitis Laboratory : Distribution ... · Alphalabs 1 (3.1) 1 (1.6) Other 0...

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Dispatch Date : 09-Apr-2018 Page 1 Diagnostic serology hepatitis Distribution : 4275 Laboratory : Operated by Public Health England NIS - Specialist Microbiology Services 133-155 Waterloo Road Wellington House London SE1 8UG © Copyright. The data in UK NEQAS reports are confidential. Participants must consult the scheme organiser before quoting data from the scheme. UK NEQAS for Microbiology PO Box 63003 London NW9 1GH Published at 8:17 on Thursday 12 July 2018 Your Score Intended Result Your Report Specimen 4363 HAV IgM negative HAV IgM negative 2 CMV IgM negative CMV IgM negative 2 Acute EBV positive Acute EBV positive 2 Specimen 4364 HAV IgM negative HAV IgM negative 2 CMV IgM positive CMV IgM positive 2 Acute EBV negative Acute EBV negative 2 Specimen 4365 HAV IgM positive HAV IgM positive 2 CMV IgM negative CMV IgM negative 2 Acute EBV negative Acute EBV negative 2 Cumulative score information Total number of specimens sent to you for UK NEQAS for Diagnostic serology hepatitis over the last 2 distributions is 6 For these distributions specimen numbers 4045 4046 4047 4363 4364 4365 have been sent. Number of specimens received too late for analysis (not scored) 0 Your cumulative score for the specimen/test combinations that you reported was 32 out of a possible 32 The mean score calculated from the reports returned by UK laboratories testing the specimen/test combinations you examined was 31.71 with a standard error of 1.26. Performance rating Your performance rating for UK NEQAS for Diagnostic serology hepatitis (i.e.the number of standard errors by which your cumulative score lies above or below the mean for UK laboratories) is 0.23 A performance rating of more than 1.96 standard errors below the mean indicates possible poor performance. Your performance rating may change if other participants' results are amended. Comments : Overall 99.5% of participants reported correct results for HAV IgM, 99.3% for CMV IgM and 98.3% for acute EBV markers. Turn around time: The time taken to report your results was 0-day(s). This information is provided for your own use and does not form part of your performance assessment. Enquiries : Any queries about this distribution can be addressed to Dr Beatrix Kele at the address below. For repeat specimens please order using the web form or e-mail [email protected] stating your laboratory identification number, the distribution name and number, and the specimen number(s). Acknowledgments : We thank colleagues at the PHE-NIS-Public Health Laboratory Southampton, Manchester and Bristol; Royal Free Hospital, London and Department of Microbiology, Gloucestershire Royal Hospital for help with pre-distribution testing. Report authorised by: Dr Sanjiv Rughooputh, Scheme Organiser. Performance Rating Distribution Your performance rating over the past 12 distributions Your current performance rating is 0.23 MICPERF2 3116 3222 3322 3457 3546 3668 3759 3891 3984 4076 4173 4275 -4 -3 -2 -1 0 1 2 All UK Total score Distribution Total score you achieved for each of the last 12 distributions Your total score for this distribution is 18 MICPERF2X 3116 3222 3322 3457 3546 3668 3759 3891 3984 4076 4173 4275 0 4 8 12 16 20 of 10
Transcript
Page 1: Diagnostic serology hepatitis Laboratory : Distribution ... · Alphalabs 1 (3.1) 1 (1.6) Other 0 (0.0) 1 (1.6) Unspecified 0 (0.0) 1 (1.6) Labena: MINITOP 0 (0.0) 2 (3.2) PBM: BioSign

Dispatch Date : 09-Apr-2018

Page 1

Diagnostic serology hepatitis

Distribution : 4275

Laboratory :

Operated by Public Health England NIS - Specialist Microbiology Services 133-155 Waterloo Road Wellington House London SE1 8UG

© Copyright. The data in UK NEQAS reports are confidential. Participants must consult the scheme organiser before quoting data from the scheme. UK NEQAS for Microbiology PO Box 63003 London NW9 1GH Published at 8:17 on Thursday 12 July 2018

Your Score Intended Result Your Report

Specimen 4363 HAV IgM negative HAV IgM negative 2 CMV IgM negative CMV IgM negative 2 Acute EBV positive Acute EBV positive 2

Specimen 4364 HAV IgM negative HAV IgM negative 2 CMV IgM positive CMV IgM positive 2 Acute EBV negative Acute EBV negative 2

Specimen 4365 HAV IgM positive HAV IgM positive 2 CMV IgM negative CMV IgM negative 2 Acute EBV negative Acute EBV negative 2

Cumulative score information Total number of specimens sent to you for UK NEQAS for Diagnostic serology hepatitis over the last 2 distributions is 6 For these distributions specimen numbers 4045 4046 4047 4363 4364 4365 have been sent. Number of specimens received too late for analysis (not scored) 0 Your cumulative score for the specimen/test combinations that you reported was 32 out of a possible 32 The mean score calculated from the reports returned by UK laboratories testing the specimen/test combinations you examined was 31.71 with a standard error of 1.26. Performance rating Your performance rating for UK NEQAS for Diagnostic serology hepatitis (i.e.the number of standard errors by which your cumulative score lies above or below the mean for UK laboratories) is 0.23 A performance rating of more than 1.96 standard errors below the mean indicates possible poor performance. Your performance rating may change if other participants' results are amended.

Comments : Overall 99.5% of participants reported correct results for HAV IgM, 99.3% for CMV IgM and 98.3% for acute EBV markers. Turn around time: The time taken to report your results was 0-day(s). This information is provided for your own use and does not form part of your performance assessment. Enquiries : Any queries about this distribution can be addressed to Dr Beatrix Kele at the address below. For repeat specimens please order using the web form or e-mail [email protected] stating your laboratory identification number, the distribution name and number, and the specimen number(s). Acknowledgments : We thank colleagues at the PHE-NIS-Public Health Laboratory Southampton, Manchester and Bristol; Royal Free Hospital, London and Department of Microbiology, Gloucestershire Royal Hospital for help with pre-distribution testing. Report authorised by: Dr Sanjiv Rughooputh, Scheme Organiser.

Per

form

ance

Rat

ing

Distribution

Your performance rating over the past 12 distributions Your current performance rating is 0.23

MICPERF2

3116 3222 3322 3457 3546 3668 3759 3891 3984 4076 4173 4275-4

-3

-2

-1

0

1

2

All

UK

Tot

al s

core

Distribution

Total score you achieved for each of the last 12 distributionsYour total score for this distribution is 18

MICPERF2X

3116 3222 3322 3457 3546 3668 3759 3891 3984 4076 4173 42750

4

8

12

16

20

of 10

Page 2: Diagnostic serology hepatitis Laboratory : Distribution ... · Alphalabs 1 (3.1) 1 (1.6) Other 0 (0.0) 1 (1.6) Unspecified 0 (0.0) 1 (1.6) Labena: MINITOP 0 (0.0) 2 (3.2) PBM: BioSign

Dispatch Date : 09-Apr-2018

Page 2

Diagnostic serology hepatitis

Distribution : 4275

Laboratory :

Operated by Public Health England NIS - Specialist Microbiology Services 133-155 Waterloo Road Wellington House London SE1 8UG

© Copyright. The data in UK NEQAS reports are confidential. Participants must consult the scheme organiser before quoting data from the scheme. UK NEQAS for Microbiology PO Box 63003 London NW9 1GH Published at 8:17 on Thursday 12 July 2018

Three specimens were dispatched with a request to report on the presence of hepatitis A virus (HAV) IgM, cytomegalovirus (CMV) IgM and markers of acute infection due to Epstein-Barr virus (EBV). All specimens were derived from thrombinised human plasma donations. Specimens 4363, 4364 and 4365 were diluted 1:1.1, 1:2 and 1:6 respectively.

Specimen : 4363 HAV IgM negative

UK (%) All (%)

27 (20.9) 34 (11.8)bioMerieux : Vidas46 (35.7) 127 (43.9)Abbott : Architect

0 (0.0) 1 (0.3)Wantai: ELISA0 (0.0) 2 (0.7)Dia.Pro1 (0.8) 2 (0.7)Beckman0 (0.0) 2 (0.7)DiaSorin1 (0.8) 2 (0.7)Unspecified0 (0.0) 3 (1.0)OCD : VITROS6 (4.7) 6 (2.1)Beckman : Access7 (5.4) 18 (6.2)DiaSorin : Liaison

12 (9.3) 27 (9.3)Siemens:ADVIA Centaur29 (22.5) 65 (22.5)Roche

Number of Reports0 30 60 90 120 150

Positive Equivocal Negative

Your Report : HAV IgM negative

HAV IgM equivocal

121

HAV IgM positive

280

Overall Results

281

2

% Correct

1210

99.6

------------------------------------------------------------UK

10

Total

1HAV IgM negative

0

All

100

------------------------------------------------------------

-1

Score

Your Score : 2

Specimen : 4363 CMV IgM negative

UK (%) All (%)

21 (18.8) 57 (20.7)DiaSorin : Liaison35 (31.3) 58 (21.0)bioMerieux : Vidas

0 (0.0) 2 (0.7)Nova Tec0 (0.0) 2 (0.7)OCD : VITROS0 (0.0) 2 (0.7)Euroimmun0 (0.0) 2 (0.7)DiaSorin2 (1.8) 3 (1.1)Diesse : IgM EIA0 (0.0) 6 (2.2)Siemens: Immulite5 (4.5) 6 (2.2)Beckman : Access0 (0.0) 9 (3.3)Siemens:EIA

11 (9.8) 31 (11.2)Roche36 (32.1) 93 (33.7)Abbott : Architect

Number of Reports0 20 40 60 80 100

Positive Equivocal Negative

Your Report : CMV IgM negative

CMV IgM equivocal

103

CMV IgM positive

251

Overall Results

255

2

% Correct

1022

98.4

------------------------------------------------------------UK

20

Total

1CMV IgM negative

1

All

99.0

------------------------------------------------------------

-1

Score

Your Score : 2

Specimen : 4363 Acute EBV positive

Your Report : Acute EBV positive

Acute EBV equivocal

1

Acute EBV positive

238

1

Overall Results

-1-1

------------------------------------------------------------

12

91

------------------------------------------------------------UK

2340

1

1Acute EBV negative

89

All

Total

Past EBV infection

2

Score

Your Score : 2

Operated by Public Health England NIS - Specialist Microbiology Services 133-155 Waterloo Road Wellington House London SE1 8UG

© Copyright. The data in UK NEQAS reports are confidential. Participants must consult the scheme organiser before quoting data from the scheme. UK NEQAS for Microbiology PO Box 63003 London NW9 1GH Published at 8:17 on Thursday 12 July 2018

of 10

Page 3: Diagnostic serology hepatitis Laboratory : Distribution ... · Alphalabs 1 (3.1) 1 (1.6) Other 0 (0.0) 1 (1.6) Unspecified 0 (0.0) 1 (1.6) Labena: MINITOP 0 (0.0) 2 (3.2) PBM: BioSign

Dispatch Date : 09-Apr-2018

Page 3

Diagnostic serology hepatitis

Distribution : 4275

Laboratory :

Three specimens were dispatched with a request to report on the presence of hepatitis A virus (HAV) IgM, cytomegalovirus (CMV) IgM and markers of acute infection due to Epstein-Barr virus (EBV). All specimens were derived from thrombinised human plasma donations. Specimens 4363, 4364 and 4365 were diluted 1:1.1, 1:2 and 1:6 respectively.

Specimen : 4363 EBV VCA IgM results Histogram of EBV VCA IgM results

UK (%) All (%)

32 (36.8) 48 (20.6)bioMerieux : Vidas0 (0.0) 2 (0.9)In house0 (0.0) 2 (0.9)TGS TA0 (0.0) 3 (1.3)Vircell2 (2.3) 3 (1.3)Virion Serion2 (2.3) 4 (1.7)Meridian1 (1.1) 5 (2.1)Siemens:EIA0 (0.0) 5 (2.1)Nova Tec0 (0.0) 5 (2.1)BioRad0 (0.0) 8 (3.4)Euroimmun

21 (24.1) 61 (26.2)Abbott : Architect26 (29.9) 75 (32.2)DiaSorin : Liaison

Number of Reports0 16 32 48 64 80

Positive Equivocal Negative

Your Report : Positive

Specimen : 4363 EBV VCA IgG results Histogram of EBV VCA IgG results

UK (%) All (%)

26 (36.1) 70 (33.8)DiaSorin : Liaison0 (0.0) 2 (1.0)In house0 (0.0) 2 (1.0)TGS TA0 (0.0) 3 (1.4)Vircell1 (1.4) 3 (1.4)DiaSorin0 (0.0) 3 (1.4)Unspecified1 (1.4) 4 (1.9)Siemens:EIA0 (0.0) 4 (1.9)Nova Tec0 (0.0) 5 (2.4)BioRad0 (0.0) 7 (3.4)Euroimmun

22 (30.6) 37 (17.9)bioMerieux : Vidas18 (25.0) 55 (26.6)Abbott : Architect

Number of Reports0 16 32 48 64 80

Positive Equivocal Negative

Your Report : Positive

Operated by Public Health England NIS - Specialist Microbiology Services 133-155 Waterloo Road Wellington House London SE1 8UG

© Copyright. The data in UK NEQAS reports are confidential. Participants must consult the scheme organiser before quoting data from the scheme. UK NEQAS for Microbiology PO Box 63003 London NW9 1GH Published at 8:17 on Thursday 12 July 2018

of 10

Page 4: Diagnostic serology hepatitis Laboratory : Distribution ... · Alphalabs 1 (3.1) 1 (1.6) Other 0 (0.0) 1 (1.6) Unspecified 0 (0.0) 1 (1.6) Labena: MINITOP 0 (0.0) 2 (3.2) PBM: BioSign

Dispatch Date : 09-Apr-2018

Page 4

Diagnostic serology hepatitis

Distribution : 4275

Laboratory :

Three specimens were dispatched with a request to report on the presence of hepatitis A virus (HAV) IgM, cytomegalovirus (CMV) IgM and markers of acute infection due to Epstein-Barr virus (EBV). All specimens were derived from thrombinised human plasma donations. Specimens 4363, 4364 and 4365 were diluted 1:1.1, 1:2 and 1:6 respectively.

Specimen : 4363 EBV EBNA IgG results Histogram of EBV EBNA IgG results

UK (%) All (%)

25 (30.9) 69 (32.7)DiaSorin : Liaison0 (0.0) 1 (0.5)bioMerieux0 (0.0) 1 (0.5)Unspecified1 (1.2) 2 (0.9)Siemens:EIA2 (2.5) 2 (0.9)Diesse : Chorus0 (0.0) 2 (0.9)TGS TA0 (0.0) 3 (1.4)Vircell0 (0.0) 5 (2.4)BioRad1 (1.2) 6 (2.8)Nova Tec0 (0.0) 7 (3.3)Euroimmun

29 (35.8) 46 (21.8)bioMerieux : Vidas19 (23.5) 58 (27.5)Abbott : Architect

Number of Reports0 16 32 48 64 80

Positive Equivocal Negative

Your Report : Positive

Specimen : 4363 EBV Heterophile results Histogram of EBV Heterophile results

UK (%) All (%)

13 (40.6) 15 (24.2)Biokit: Monogen0 (0.0) 1 (1.6)Diesse1 (3.1) 1 (1.6)Alphalabs0 (0.0) 1 (1.6)Other0 (0.0) 1 (1.6)Unspecified0 (0.0) 2 (3.2)Labena: MINITOP2 (6.3) 2 (3.2)PBM: BioSign2 (6.3) 2 (3.2)Launch Biokit0 (0.0) 3 (4.8)BioRad1 (3.1) 4 (6.5)Meridian: Monospot3 (9.4) 8 (12.9)Clearview9 (28.1) 16 (25.8)Unipath Clearview

Number of Reports0 4 8 12 16 20

Positive Equivocal Negative

Your Report : Positive

Specimen : 4363 EBV EA IgG results Histogram of EBV EA IgG results

UK (%) All (%)

0 (0.0) 1 (3.6)Microgen0 (0.0) 1 (3.6)TGS TA0 (0.0) 2 (7.1)Euroimmun Immunoblot0 (0.0) 2 (7.1)BioRad0 (0.0) 4 (14.3)Euroimmun0 (0.0) 18 (64.3)DiaSorin : Liaison

Number of Reports0 4 8 12 16 20

Positive Equivocal Negative

Your Report : Not examined

Operated by Public Health England NIS - Specialist Microbiology Services 133-155 Waterloo Road Wellington House London SE1 8UG

© Copyright. The data in UK NEQAS reports are confidential. Participants must consult the scheme organiser before quoting data from the scheme. UK NEQAS for Microbiology PO Box 63003 London NW9 1GH Published at 8:17 on Thursday 12 July 2018

of 10

Page 5: Diagnostic serology hepatitis Laboratory : Distribution ... · Alphalabs 1 (3.1) 1 (1.6) Other 0 (0.0) 1 (1.6) Unspecified 0 (0.0) 1 (1.6) Labena: MINITOP 0 (0.0) 2 (3.2) PBM: BioSign

Dispatch Date : 09-Apr-2018

Page 5

Diagnostic serology hepatitis

Distribution : 4275

Laboratory :

Three specimens were dispatched with a request to report on the presence of hepatitis A virus (HAV) IgM, cytomegalovirus (CMV) IgM and markers of acute infection due to Epstein-Barr virus (EBV). All specimens were derived from thrombinised human plasma donations. Specimens 4363, 4364 and 4365 were diluted 1:1.1, 1:2 and 1:6 respectively.

Specimen : 4364 HAV IgM negative

UK (%) All (%)

27 (20.9) 34 (11.8)bioMerieux : Vidas46 (35.7) 128 (44.3)Abbott : Architect

0 (0.0) 1 (0.3)Wantai: ELISA0 (0.0) 2 (0.7)Dia.Pro1 (0.8) 2 (0.7)Beckman0 (0.0) 2 (0.7)DiaSorin1 (0.8) 2 (0.7)Unspecified0 (0.0) 3 (1.0)OCD : VITROS6 (4.7) 6 (2.1)Beckman : Access7 (5.4) 17 (5.9)DiaSorin : Liaison

12 (9.3) 27 (9.3)Siemens:ADVIA Centaur29 (22.5) 65 (22.5)Roche

Number of Reports0 30 60 90 120 150

Positive Equivocal Negative

Your Report : HAV IgM negative

HAV IgM equivocal

121

HAV IgM positive

279

Overall Results

281

2

% Correct

1210

99.3

------------------------------------------------------------UK

20

Total

HAV IgM negative1

0

All

100

------------------------------------------------------------

-1

Score

Your Score : 2

Specimen : 4364 CMV IgM positive

UK (%) All (%)

21 (18.8) 57 (19.9)DiaSorin : Liaison35 (31.3) 66 (23.1)bioMerieux : Vidas

0 (0.0) 1 (0.3)Beckman0 (0.0) 2 (0.7)OCD : VITROS0 (0.0) 2 (0.7)Euroimmun0 (0.0) 2 (0.7)DiaSorin2 (1.8) 3 (1.0)Diesse : IgM EIA0 (0.0) 6 (2.1)Siemens: Immulite5 (4.5) 6 (2.1)Beckman : Access0 (0.0) 11 (3.8)Siemens:EIA

11 (9.8) 31 (10.8)Roche36 (32.1) 94 (32.9)Abbott : Architect

Number of Reports0 20 40 60 80 100

Positive Equivocal Negative

Your Report : CMV IgM positive

CMV IgM equivocal

103

CMV IgM positive

1

Overall Results

255

-1

% Correct

00

99.6

------------------------------------------------------------UK

2540

Total

1CMV IgM negative

103

All

100

------------------------------------------------------------

2

Score

Your Score : 2

Specimen : 4364 Acute EBV negative

Your Report : Acute EBV negative

Acute EBV equivocal

213

Acute EBV positive

240

24

Overall Results

22

------------------------------------------------------------

151

92

------------------------------------------------------------UK

20

76

1Acute EBV negative

1

All

Total

Past EBV infection

-1

Score

Your Score : 2

Operated by Public Health England NIS - Specialist Microbiology Services 133-155 Waterloo Road Wellington House London SE1 8UG

© Copyright. The data in UK NEQAS reports are confidential. Participants must consult the scheme organiser before quoting data from the scheme. UK NEQAS for Microbiology PO Box 63003 London NW9 1GH Published at 8:17 on Thursday 12 July 2018

of 10

Page 6: Diagnostic serology hepatitis Laboratory : Distribution ... · Alphalabs 1 (3.1) 1 (1.6) Other 0 (0.0) 1 (1.6) Unspecified 0 (0.0) 1 (1.6) Labena: MINITOP 0 (0.0) 2 (3.2) PBM: BioSign

Dispatch Date : 09-Apr-2018

Page 6

Diagnostic serology hepatitis

Distribution : 4275

Laboratory :

Three specimens were dispatched with a request to report on the presence of hepatitis A virus (HAV) IgM, cytomegalovirus (CMV) IgM and markers of acute infection due to Epstein-Barr virus (EBV). All specimens were derived from thrombinised human plasma donations. Specimens 4363, 4364 and 4365 were diluted 1:1.1, 1:2 and 1:6 respectively.

Specimen : 4364 EBV VCA IgM results Histogram of EBV VCA IgM results

UK (%) All (%)

28 (36.8) 44 (20.0)bioMerieux : Vidas0 (0.0) 2 (0.9)In house0 (0.0) 2 (0.9)TGS TA0 (0.0) 3 (1.4)Vircell2 (2.6) 3 (1.4)Virion Serion2 (2.6) 4 (1.8)Meridian1 (1.3) 5 (2.3)Siemens:EIA0 (0.0) 5 (2.3)Nova Tec0 (0.0) 5 (2.3)BioRad0 (0.0) 7 (3.2)Euroimmun

17 (22.4) 57 (25.9)Abbott : Architect24 (31.6) 72 (32.7)DiaSorin : Liaison

Number of Reports0 16 32 48 64 80

Positive Equivocal Negative

Your Report : Negative

Specimen : 4364 EBV VCA IgG results Histogram of EBV VCA IgG results

UK (%) All (%)

21 (36.2) 65 (33.9)DiaSorin : Liaison0 (0.0) 2 (1.0)In house0 (0.0) 2 (1.0)TGS TA0 (0.0) 3 (1.6)Vircell1 (1.7) 3 (1.6)DiaSorin0 (0.0) 3 (1.6)Unspecified1 (1.7) 4 (2.1)Siemens:EIA0 (0.0) 4 (2.1)Nova Tec0 (0.0) 5 (2.6)BioRad0 (0.0) 6 (3.1)Euroimmun

19 (32.8) 34 (17.7)bioMerieux : Vidas13 (22.4) 50 (26.0)Abbott : Architect

Number of Reports0 16 32 48 64 80

Positive Equivocal Negative

Your Report : Positive

Operated by Public Health England NIS - Specialist Microbiology Services 133-155 Waterloo Road Wellington House London SE1 8UG

© Copyright. The data in UK NEQAS reports are confidential. Participants must consult the scheme organiser before quoting data from the scheme. UK NEQAS for Microbiology PO Box 63003 London NW9 1GH Published at 8:17 on Thursday 12 July 2018

of 10

Page 7: Diagnostic serology hepatitis Laboratory : Distribution ... · Alphalabs 1 (3.1) 1 (1.6) Other 0 (0.0) 1 (1.6) Unspecified 0 (0.0) 1 (1.6) Labena: MINITOP 0 (0.0) 2 (3.2) PBM: BioSign

Dispatch Date : 09-Apr-2018

Page 7

Diagnostic serology hepatitis

Distribution : 4275

Laboratory :

Three specimens were dispatched with a request to report on the presence of hepatitis A virus (HAV) IgM, cytomegalovirus (CMV) IgM and markers of acute infection due to Epstein-Barr virus (EBV). All specimens were derived from thrombinised human plasma donations. Specimens 4363, 4364 and 4365 were diluted 1:1.1, 1:2 and 1:6 respectively.

Specimen : 4364 EBV EBNA IgG results Histogram of EBV EBNA IgG results

UK (%) All (%)

22 (28.2) 64 (31.1)DiaSorin : Liaison0 (0.0) 1 (0.5)bioMerieux0 (0.0) 1 (0.5)Unspecified1 (1.3) 2 (1.0)Siemens:EIA2 (2.6) 2 (1.0)Diesse : Chorus0 (0.0) 2 (1.0)TGS TA0 (0.0) 3 (1.5)Vircell0 (0.0) 5 (2.4)BioRad1 (1.3) 6 (2.9)Nova Tec0 (0.0) 7 (3.4)Euroimmun

29 (37.2) 46 (22.3)bioMerieux : Vidas19 (24.4) 59 (28.6)Abbott : Architect

Number of Reports0 16 32 48 64 80

Positive Equivocal Negative

Your Report : Positive

Specimen : 4364 EBV Heterophile results Histogram of EBV Heterophile results

UK (%) All (%)

13 (43.3) 15 (25.4)Biokit: Monogen0 (0.0) 1 (1.7)Diesse1 (3.3) 1 (1.7)Alphalabs0 (0.0) 1 (1.7)Other0 (0.0) 1 (1.7)Unspecified0 (0.0) 2 (3.4)Labena: MINITOP2 (6.7) 2 (3.4)PBM: BioSign2 (6.7) 2 (3.4)Launch Biokit0 (0.0) 3 (5.1)BioRad1 (3.3) 4 (6.8)Meridian: Monospot3 (10.0) 8 (13.6)Clearview8 (26.7) 14 (23.7)Unipath Clearview

Number of Reports0 4 8 12 16 20

Positive Equivocal Negative

Your Report : Negative

Specimen : 4364 EBV EA IgG results Histogram of EBV EA IgG results

UK (%) All (%)

0 (0.0) 1 (4.0)TGS TA0 (0.0) 2 (8.0)Euroimmun Immunoblot0 (0.0) 2 (8.0)BioRad0 (0.0) 3 (12.0)Euroimmun0 (0.0) 17 (68.0)DiaSorin : Liaison

Number of Reports0 4 8 12 16 20

Positive Equivocal Negative

Your Report : Not examined

Operated by Public Health England NIS - Specialist Microbiology Services 133-155 Waterloo Road Wellington House London SE1 8UG

© Copyright. The data in UK NEQAS reports are confidential. Participants must consult the scheme organiser before quoting data from the scheme. UK NEQAS for Microbiology PO Box 63003 London NW9 1GH Published at 8:17 on Thursday 12 July 2018

of 10

Page 8: Diagnostic serology hepatitis Laboratory : Distribution ... · Alphalabs 1 (3.1) 1 (1.6) Other 0 (0.0) 1 (1.6) Unspecified 0 (0.0) 1 (1.6) Labena: MINITOP 0 (0.0) 2 (3.2) PBM: BioSign

Dispatch Date : 09-Apr-2018

Page 8

Diagnostic serology hepatitis

Distribution : 4275

Laboratory :

Three specimens were dispatched with a request to report on the presence of hepatitis A virus (HAV) IgM, cytomegalovirus (CMV) IgM and markers of acute infection due to Epstein-Barr virus (EBV). All specimens were derived from thrombinised human plasma donations. Specimens 4363, 4364 and 4365 were diluted 1:1.1, 1:2 and 1:6 respectively.

Specimen : 4365 HAV IgM positive

UK (%) All (%)

31 (23.3) 38 (13.0)bioMerieux : Vidas46 (34.6) 128 (43.8)Abbott : Architect

0 (0.0) 1 (0.3)Wantai: ELISA0 (0.0) 2 (0.7)Dia.Pro1 (0.8) 2 (0.7)Beckman0 (0.0) 2 (0.7)DiaSorin1 (0.8) 2 (0.7)Unspecified0 (0.0) 3 (1.0)OCD : VITROS6 (4.5) 6 (2.1)Beckman : Access7 (5.3) 17 (5.8)DiaSorin : Liaison

12 (9.0) 27 (9.2)Siemens:ADVIA Centaur29 (21.8) 64 (21.9)Roche

Number of Reports0 30 60 90 120 150

Positive Equivocal Negative

Your Report : HAV IgM positive

HAV IgM equivocal

121

HAV IgM positive

1

Overall Results

280

-1

% Correct

00

99.6

------------------------------------------------------------UK

2790

Total

HAV IgM negative1

121

All

100

------------------------------------------------------------

2

Score

Your Score : 2

Specimen : 4365 CMV IgM negative

UK (%) All (%)

21 (18.9) 57 (20.9)DiaSorin : Liaison34 (30.6) 57 (20.9)bioMerieux : Vidas

0 (0.0) 1 (0.4)Beckman0 (0.0) 2 (0.7)OCD : VITROS0 (0.0) 2 (0.7)Euroimmun0 (0.0) 2 (0.7)DiaSorin2 (1.8) 3 (1.1)Diesse : IgM EIA0 (0.0) 6 (2.2)Siemens: Immulite5 (4.5) 6 (2.2)Beckman : Access0 (0.0) 9 (3.3)Siemens:EIA

11 (9.9) 30 (11.0)Roche36 (32.4) 93 (34.1)Abbott : Architect

Number of Reports0 20 40 60 80 100

Positive Equivocal Negative

Your Report : CMV IgM negative

CMV IgM equivocal

103

CMV IgM positive

254

Overall Results

254

2

% Correct

1030

100

------------------------------------------------------------UK

00

Total

1CMV IgM negative

0

All

100

------------------------------------------------------------

-1

Score

Your Score : 2

Specimen : 4365 Acute EBV negative

Your Report : Acute EBV negative

Acute EBV equivocal

208

Acute EBV positive

239

26

Overall Results

22

------------------------------------------------------------

164

92

------------------------------------------------------------UK

13

73

1Acute EBV negative

0

All

Total

Past EBV infection

-1

Score

Your Score : 2

Operated by Public Health England NIS - Specialist Microbiology Services 133-155 Waterloo Road Wellington House London SE1 8UG

© Copyright. The data in UK NEQAS reports are confidential. Participants must consult the scheme organiser before quoting data from the scheme. UK NEQAS for Microbiology PO Box 63003 London NW9 1GH Published at 8:17 on Thursday 12 July 2018

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Page 9: Diagnostic serology hepatitis Laboratory : Distribution ... · Alphalabs 1 (3.1) 1 (1.6) Other 0 (0.0) 1 (1.6) Unspecified 0 (0.0) 1 (1.6) Labena: MINITOP 0 (0.0) 2 (3.2) PBM: BioSign

Dispatch Date : 09-Apr-2018

Page 9

Diagnostic serology hepatitis

Distribution : 4275

Laboratory :

Three specimens were dispatched with a request to report on the presence of hepatitis A virus (HAV) IgM, cytomegalovirus (CMV) IgM and markers of acute infection due to Epstein-Barr virus (EBV). All specimens were derived from thrombinised human plasma donations. Specimens 4363, 4364 and 4365 were diluted 1:1.1, 1:2 and 1:6 respectively.

Specimen : 4365 EBV VCA IgM results Histogram of EBV VCA IgM results

UK (%) All (%)

28 (36.8) 44 (20.1)bioMerieux : Vidas0 (0.0) 2 (0.9)In house0 (0.0) 2 (0.9)TGS TA0 (0.0) 3 (1.4)Vircell2 (2.6) 3 (1.4)Virion Serion2 (2.6) 4 (1.8)Meridian1 (1.3) 5 (2.3)Siemens:EIA0 (0.0) 5 (2.3)Nova Tec0 (0.0) 5 (2.3)BioRad0 (0.0) 7 (3.2)Euroimmun

17 (22.4) 57 (26.0)Abbott : Architect24 (31.6) 71 (32.4)DiaSorin : Liaison

Number of Reports0 16 32 48 64 80

Positive Equivocal Negative

Your Report : Negative

Specimen : 4365 EBV VCA IgG results Histogram of EBV VCA IgG results

UK (%) All (%)

21 (36.8) 65 (34.0)DiaSorin : Liaison0 (0.0) 2 (1.0)In house0 (0.0) 2 (1.0)TGS TA0 (0.0) 3 (1.6)Vircell1 (1.8) 3 (1.6)DiaSorin0 (0.0) 3 (1.6)Unspecified1 (1.8) 4 (2.1)Siemens:EIA0 (0.0) 4 (2.1)Nova Tec0 (0.0) 5 (2.6)BioRad0 (0.0) 6 (3.1)Euroimmun

19 (33.3) 34 (17.8)bioMerieux : Vidas12 (21.1) 49 (25.7)Abbott : Architect

Number of Reports0 16 32 48 64 80

Positive Equivocal Negative

Your Report : Positive

Operated by Public Health England NIS - Specialist Microbiology Services 133-155 Waterloo Road Wellington House London SE1 8UG

© Copyright. The data in UK NEQAS reports are confidential. Participants must consult the scheme organiser before quoting data from the scheme. UK NEQAS for Microbiology PO Box 63003 London NW9 1GH Published at 8:17 on Thursday 12 July 2018

of 10

Page 10: Diagnostic serology hepatitis Laboratory : Distribution ... · Alphalabs 1 (3.1) 1 (1.6) Other 0 (0.0) 1 (1.6) Unspecified 0 (0.0) 1 (1.6) Labena: MINITOP 0 (0.0) 2 (3.2) PBM: BioSign

Dispatch Date : 09-Apr-2018

Page 10

Diagnostic serology hepatitis

Distribution : 4275

Laboratory :

Three specimens were dispatched with a request to report on the presence of hepatitis A virus (HAV) IgM, cytomegalovirus (CMV) IgM and markers of acute infection due to Epstein-Barr virus (EBV). All specimens were derived from thrombinised human plasma donations. Specimens 4363, 4364 and 4365 were diluted 1:1.1, 1:2 and 1:6 respectively.

Specimen : 4365 EBV EBNA IgG results Histogram of EBV EBNA IgG results

UK (%) All (%)

22 (28.2) 64 (31.1)DiaSorin : Liaison0 (0.0) 1 (0.5)bioMerieux0 (0.0) 1 (0.5)Unspecified1 (1.3) 2 (1.0)Siemens:EIA2 (2.6) 2 (1.0)Diesse : Chorus0 (0.0) 2 (1.0)TGS TA0 (0.0) 3 (1.5)Vircell0 (0.0) 5 (2.4)BioRad1 (1.3) 6 (2.9)Nova Tec0 (0.0) 7 (3.4)Euroimmun

29 (37.2) 46 (22.3)bioMerieux : Vidas19 (24.4) 59 (28.6)Abbott : Architect

Number of Reports0 16 32 48 64 80

Positive Equivocal Negative

Your Report : Positive

Specimen : 4365 EBV Heterophile results Histogram of EBV Heterophile results

UK (%) All (%)

13 (43.3) 15 (25.4)Biokit: Monogen0 (0.0) 1 (1.7)Diesse1 (3.3) 1 (1.7)Alphalabs0 (0.0) 1 (1.7)Other0 (0.0) 1 (1.7)Unspecified0 (0.0) 2 (3.4)Labena: MINITOP2 (6.7) 2 (3.4)PBM: BioSign2 (6.7) 2 (3.4)Launch Biokit0 (0.0) 3 (5.1)BioRad1 (3.3) 4 (6.8)Meridian: Monospot3 (10.0) 8 (13.6)Clearview8 (26.7) 14 (23.7)Unipath Clearview

Number of Reports0 4 8 12 16 20

Positive Equivocal Negative

Your Report : Negative

Specimen : 4365 EBV EA IgG results Histogram of EBV EA IgG results

UK (%) All (%)

0 (0.0) 1 (4.0)TGS TA0 (0.0) 2 (8.0)Euroimmun Immunoblot0 (0.0) 2 (8.0)BioRad0 (0.0) 3 (12.0)Euroimmun0 (0.0) 17 (68.0)DiaSorin : Liaison

Number of Reports0 4 8 12 16 20

Positive Equivocal Negative

Your Report : Not examined

Operated by Public Health England NIS - Specialist Microbiology Services 133-155 Waterloo Road Wellington House London SE1 8UG

© Copyright. The data in UK NEQAS reports are confidential. Participants must consult the scheme organiser before quoting data from the scheme. UK NEQAS for Microbiology PO Box 63003 London NW9 1GH Published at 8:17 on Thursday 12 July 2018

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