CONFIRMED FACULTY

Douglas Arthur, MD VCU Massey Cancer Center

Andrea Barrio, MD Memorial Sloan Kettering Cancer Center

Harold Burstein, MD, PhD Harvard Medical Center

Lisa Carey, MD University of North Carolina – Lineberger Comprehensive Cancer Center

Massimo Cristofanilli, MD Robert H. Lurie Comprehensive Cancer Center of Northwestern University

Mary Disis, MD University of Washington

Armando Giuliano, MD Cedars-Sinai Medical Center

William Gradishar, MD Robert H. Lurie Comprehensive Cancer Center of Northwestern University

Nora Hansen, MD Robert H. Lurie Comprehensive Cancer Center of Northwestern University

Jennifer Harvey, MD University of Virginia

Claudine Isaacs, MD Lombardi Cancer Center Georgetown University

Maxine Jochelson, MD Memorial Sloan Kettering Cancer Center

Steven Katz, MD, MPH University of Michigan

Seema Khan, MD Robert H. Lurie Comprehensive Cancer Center of Northwestern University

Tari King, MD Dana-Farber/Brigham and Womens Cancer Center

Mario Lacouture, MD Memorial Sloan Kettering Cancer Center

Cynthia Ma, MD, PhD Washington University School of Medicine in St Louis

Sarah McLaughlin, MD Mayo Clinic

Elizabeth Mittendorf, MD, PhD MD Anderson Cancer Center The University of Texas

Meena Moran, MD Yale University School of Medicine

Monica Morrow, MD Memorial Sloan Kettering Cancer Center

Lisa Newman, MD Henry Ford Health System

Ruth O’Regan, MD University of Wisconsin Carbone Cancer Center

Mark Robson, MD Memorial Sloan Kettering Cancer Center

Mikel Ross, MSN Memorial Sloan Kettering Cancer Center

Stuart Schnitt, MD Dana-Farber/Brigham and Womens Cancer Center

Kalliopi Siziopikou, MD, PhD Robert H. Lurie Comprehensive Cancer Center of Northwestern University

George Sledge, Jr., MD Stanford University

Jonathan Strauss, MD Robert H. Lurie Comprehensive Cancer Center of Northwestern University

Todd Tuttle, MD University of Minnesota

Giuseppe Viale, MD University of Milan

Julia White, MD Ohio State University James Comprehensive Cancer Center

Eric Winer, MD Dana-Farber Cancer Institute/Harvard Medical School

Faculty Disclosure Current guidelines state that participants in CME activities should be made aware of any affiliation of financial interest that may affect the speaker’s presentation. Each speaker has been requested to complete a faculty disclosure form. (The names of faculty members declaring a relationship or who will be discussing off-label usage will be indicated in the course syllabus.)

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LYNN SAGE BREAST CANCER SYMPOSIUMOCTOBER 11-14, 2018Chicago Marriott Downtown Magnificent Mile

20TH

ANNUAL

LYNN SAGE DISTINGUISHED LECTURER A FRONTLINE VIEW OF THE LAST 20 YEARS AND WHERE WE GO NEXT William Gradishar, MD

THE CONNIE MOSKOW MEMORIAL LECTURE IMMUNOLOGY AND BREAST CANCERMary Disis, MD

SYMPOSIUM CHAIR William Gradishar, MD SYMPOSIUM CO-CHAIRS Monica Morrow, MD Nora Hansen, MD

Referred to as the most valuable breast cancer meeting worldwide for the practicing clinician, the Lynn Sage Breast Cancer Symposium provides 3.5 days of formal presentations and interactive case discussions. For 20 years, this multidisciplinary CME program has been bringing together leading national and international medical, surgical, and radiation oncologists to present, debate, and evaluate cutting-edge technology and approaches in the management of breast cancer.

Progress across all aspects of patient care, including prevention, screening, detection, and survivorship, as well as in the primary treatment modalities of surgery, radiation therapy, endocrine therapy, cytotoxic chemotherapy, and novel biologic therapies are leading to new strategies and therapeutic options. The symposium focuses on the close cooperation required for effective multidisciplinary management of patients with breast cancer.

Educational Objectives

At the conclusion of this activity, participants will be able to:

» Describe factors which influence breast cancer in the African American population;

» Examine the incidence of lymphedema and treatment options;

» Discuss the role of new AJCC staging system and importance of biomarkers;

» Cite the role of axillary surgery today in the breast cancer patient;

» Define genomic testing options, which ones to use, and review need in metastatic breast cancer;

» Review optimal adjuvant therapy in the young patient and describe risk of local regional recurrence in young patients.

PROGRAM DESCRIPTION

Register by August 31, 2018 for early bird discount

LYNN SAGE BREAST CANCER SYMPOSIUMOCTOBER 11-14, 2018Chicago Marriott Downtown Magnificent Mile

8:00 am Breakfast & Exhibits

9:00 am Symposium Welcome William Gradishar, MD Symposium Chair

Session 1: Supportive Oncology and Special Populations Session Chair: Nora Hansen, MD

9:15 am Scalp Cooling: A New Standard of Care? Mikel Ross, MSN

9:45 am Breast Cancer in African Americans Lisa Newman, MD

10:15 am Lymphedema Management Sarah McLaughlin, MD

10:45 am Diagnosing and Managing Skin Toxicity Mario Lacouture, MD

11:15 am Q&A

11:30 am Lunch

Session 2: Breast Pathology for the Non-Pathologist Session Chair: Kalliopi Siziopikou, MD, PhD

1:00 pm Phyllodes Tumors in 2018 Andrea Barrio, MD

1:30 pm The New AJCC Staging System: Rationale and Clinical Elizabeth Mittendorf, MD, PhD

2:00 pm The Immune Tumor Microenvironment in Breast Carcinomas: Pathologic Evaluation and Significance Kalliopi Siziopikou, MD, PhD

2:30 pm Ki67: Is it Worth Doing? Giuseppe Viale, MD

3:00 pm Q&A

3:15 pm Break

Session 3: Challenging Clinical Cases Session Chair: William Gradishar, MD 3:45 pm Challenging Clinical Cases Confirmed Faculty

5:00 pm Adjourn

5:00 – 6:00 pm Welcome Reception

OCTOBER 11 THURSDAY

7:30 am Breakfast & Exhibits

Session 4: Subtype-Specific Treatment Session Chair: Massimo Cristofanilli, MD

8:30 am All Triple Negative Cancers Are Not Created Equal Stuart Schnitt, MD

9:00 am Biologic Studies of Triple Negative Cancer Lisa Carey, MD

9:30 am Selecting Surgical Approach by Subtype Tari King, MD

10:00 am Break

10:30 am Should RT Approach Vary by Subtype? Julia White, MD

11:00 am Q&A

11:15 am THE CONNIE MOSKOW MEMORIAL LECTURE: Immunology and Breast Cancer Mary Disis, MD

12:15 pm Lunch

Session 5: Issues in Young Women with Breast Cancer Session Chair: Jonathan Strauss, MD

1:30 pm Imaging Strategies in Dense Breasts Jennifer Harvey, MD

2:00 pm Management of Pregnancy-Associated Breast Cancer TBD

2:30 pm Contralateral Prophylactic Mastectomy Todd Tuttle, MD

3:00 pm Break

3:30 pm Optimal Adjuvant Therapy in Young Women Mark Robson, MD

4:00 pm How Much of a Risk Factor for Locoregional Recurrence is Young Age? Meena Moran, MD

4:30 pm Management of Locoregional Recurrence Monica Morrow, MD

5:00 pm Q&A

5:15 pm Adjourn

OCTOBER 12 FRIDAY

7:30 am Breakfast & Exhibits

Session 6: Unresolved Controversies Session Chair: Seema Khan, MD

8:30 am Neoadjuvant Endocrine Therapy: Patient Selection and Outcomes Cynthia Ma, MD, PhD

9:00 am Genomic Tests for Adjuvant Therapy Decision Making: Which One is Best? Harold Burstein, MD, PhD

9:30 am Overcoming Resistance to Endocrine Therapy Ruth O’Regan, MD

10:00 am Break

10:30 am Reirradiation for Breast Conservation: Viable Option? Douglas Arthur, MD

11:00 am Q&A

11:15 am LYNN SAGE DISTINGUISHED LECTURER A Frontline View of the Last 20 Years and Where We Go Next William Gradishar, MD

12:30 pm Lunch

Session 7: The Future of Breast Cancer Treatment is Now Session Chair: Monica Morrow, MD

1:45 pm Why is It so Difficult to De-Escalate Treatment? Eric Winer, MD

2:15 pm Molecular Profiling in Metastatic Disease: Standard of Care George Sledge, Jr., MD

2:45 pm Primary Surgery of the Axilla Today and in the Future Armando Giuliano, MD

3:15 pm Break

3:30 pm Multidisciplinary Tumor Board Moderator: Monica Morrow, MD Confirmed Faculty

5:00 pm Adjourn

OCTOBER 13 SATURDAY

Session 8: Identification and Management of High Risk Women Session Chair: William Gradishar, MD

8:30 am Predisposition Mutations 2018: What’s New? Claudine Isaacs, MD

9:00 am Genetic Testing: What’s Really Happening in Practice? Steven Katz, MD, MPH

9:30 am Screening High Risk Women: Strategies and Outcomes Maxine Jochelson, MD

10:00 am Surgical Risk Reduction: Approaches and Outcomes Seema Khan, MD

10:30 am Q&A

10:45 am Adjourn

Registration Advance registration is encouraged, as space and materials are limited. The registration fee includes conference tuition, CME credits, materials, four breakfasts, breaks and an evening reception. Register online at lynnsagebreastcancer.org.

Type Discounted Regular Through August 31 After August 31

General $525 $625

Fellow/Student/Trainee $275 $375

Nurse/Physician Assistant/Nurse Practitioner $275 $375

Industry Representative $725 $825

ADDITIONAL FEES

Lunch Ticket (no refunds) $25/day

Breakout Session Ticket $50/day

Refund/Cancellation Policy Registration fees, less a $50 administrative handling fee, are refundable if a written request is received on or before September 13, 2018. No refunds will be given for lunch or breakout sessions. For further information, please call 312.695.1392 or email cancer@northwestern.edu.

Award ProgramsThe Lynn Sage Symposium Scholars Program is available for fellows and residents and the Chicago Sister Cities Medical Initiative Program is available for international physicians. Detailed information about these award programs and application processes is available online at lynnsagebreastcancer.org. Awards are made possible through the generous support of the Lynn Sage Cancer Research Foundation.

OCTOBER 14 SUNDAY