Amoebic Liver AbcessAries Budianto

Amebic liver abscess is a collection of pus in the liver in response to an intestinal parasite.It is caused by Entamoeba histolytica, the same parasite that causes amebiasis amebic dysentery. The parasite may be carried by the blood from the intestines to the liver.

The infection occurs worldwide where crowded living conditions and poor sanitation exist ( Africa, Latin America, Southeast Asia, and India)

Risk factors for amebic liver abscess include:

AlcoholismCancerImmunosuppressionMalnutritionOld agePregnancyRecent travel to a tropical regionSteroid use

trophozoites and cysts

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Entamoeba histolytica Pathology1. A Primary Ulcer Can Occur. A primary ulcer can cause rupturing of the bowel and can cause Peritonitis.

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Shows movement of trophozoites from large intestine to liver via hepatic portal vein.Liver Abscesses

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Entamoeba histolytica PathologyExtra-Intestinal Lesions and Abscess Occurs

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Entamoeba histolytica PathologyExtra-Intestinal Lesions and Abscess Occurs

A. Hepatic Amebiasis

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Entamoeba histolytica PathologyExtra-Intestinal Lesions and Abscess Occurs

A. Hepatic Amebiasis

B. Pulmonary Amebiasis

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Symptoms

Abdominal pain Particularly in the right, upper part of the abdomenIntense, continuous, or stabbing painChillsDiarrhea (in only one-third of patients)

FeverGeneral discomfort, uneasiness, or ill feeling (malaise)JaundiceJoint painLoss of appetiteSweatingWeight loss

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Exams and TestsAbdominal ultrasoundAbdominal CT scan or MRIComplete blood countLiver abscess aspiration -- to check for bacterial infection in the liver abscessLiver scanLiver function testsSerology for amebiasisStool testing for amebiasis

TreatmentAntibiotics such as metronidazole (Flagyl) or tinidazole (Tindamax). This treatment can usually be delayed until after the abscess has been treated.NEEDLE ASPIRATIONSurgical drainage

Matur Nuwun?

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