Chapter 15Intracellular Compartments and

Transport

EssentialCell Biology

Third Edition

Copyright © Garland Science 2010

backgrounds

• Membrane-Enclosed Organelles

• Protein Sorting

• Vesicular Transport

• Secretory Pathways

• Endocytic Pathways

Contents

Membrane-Enclosed Organelles

Figure 15-1 Essential Cell Biology (© Garland Science 2010)

Eucaryotic cells contain a basic set of membrane-enclose organelles

Figure 15-2 Essential Cell Biology (© Garland Science 2010)

Table 15-1 Essential Cell Biology (© Garland Science 2010)

Smooth ER

• Steroid hormone synthesis (adrenal gland)

• Organic molecules detoxified (liver cells)

• Ca2+ release and reuptake

Table 15-2 Essential Cell Biology (© Garland Science 2010)

separating one type of organelle from another

Membrane-enclose organelles evolved in different ways

1. Invagination of the plasma membrane

Figure 15-3 Essential Cell Biology (© Garland Science 2010)

The interiors of these organelles are treated by the cell in may ways as ‘extracellular’.

Why the nucleus is surrounded by two membranes.

2. Evolved from bacteria

Figure 15-4 Essential Cell Biology (© Garland Science 2010)

The similarity of the genomes to those of bacteria.

The close resemblance of some of their proteins to bacterial proteins.

These remain isolated from the extensive vesicular traffic.

Protein Sorting

background

Proteins are imported into organelles by three mechanisms

Figure 15-5 Essential Cell Biology (© Garland Science 2010)