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Copyright (c) by W. H. Freeman and Company
Chapter 9
Molecular Structure of Genes and Chromosomes
Copyright (c) by W. H. Freeman and Company
9.5 The solenoid model of condensed chromatin
Figure 9-31
Copyright (c) by W. H. Freeman and Company
9.2 Simple-sequence DNAs are concentrated in specific chromosomal locations
Figure 9-6
Copyright (c) by W. H. Freeman and Company
9.6 A model for chromatin packing in metaphase chromosomes
Figure 9-35
Copyright (c) by W. H. Freeman and Company
Copyright (c) by W. H. Freeman and Company
9.6 Experimental demonstration of chromatin loops in interphase chromosomes
Figure 9-36
Sites A-F are separated by millions of bp of linear sequence but are physically close to each other in interphase nuclei
Copyright (c) by W. H. Freeman and Company
Copyright (c) by W. H. Freeman and Company
9.6 Heterochromatin consists of chromosome regions that do not uncoil
Figure 9-39
Copyright (c) by W. H. Freeman and Company
9.6 Chromosome painting distinguishes each homologous pair by color
Figure 9-0
Copyright (c) by W. H. Freeman and Company
9.6 Stained chromosomes have characteristic banding patterns
Figure 9-38
Copyright (c) by W. H. Freeman and Company
DEFINICION MOLECULAR DE GEN
Un gen es una secuencia completa de ADN que es necesaria para la sintesis de uno o más polipéptido funcional en un momento determinado.
Regiones de ADN que codifican para moleculas de ARN como ARNt y ARNr tambien son consideradas genes.
En eucariotes, los genes permanecen en medio de segmentos no codificantes, no funcionales de ADN.
Copyright (c) by W. H. Freeman and Company
Copyright (c) by W. H. Freeman and Company
Copyright (c) by W. H. Freeman and Company
Copyright (c) by W. H. Freeman and Company
9.1 Simple and complex transcription units are found in eukaryotic genomes
Figure 9-2
Copyright (c) by W. H. Freeman and Company
9.2 Genomes of higher eukaryotes contain much nonfunctional DNA
Figure 9-3
Amongst eukaryotes, cellular DNA content does not correlate with phylogeny.
Copyright (c) by W. H. Freeman and Company
Copyright (c) by W. H. Freeman and Company
Copyright (c) by W. H. Freeman and Company
9.3 The two classes of mobile elements
Figure 9-10
Copyright (c) by W. H. Freeman and Company
Los elementos moviles probablemente tienen influencia significativa en la evolución
Mutaciones espontaneas pueden resultar de la inserción de un elemento movil dentro o cerca de una unidad de un gen.
Recombinación homologa entre elementos móviles pueden contribuir a la duplicación u otros re arreglos, incluyendo duplicacion de intrones , recombinación de intrones para creas nuevos genes y control de expresión de genes.
Copyright (c) by W. H. Freeman and Company
9.5 Nucleosomes are complexes of histones
Figure 9-30
Copyright (c) by W. H. Freeman and Company
9.7 Human mtDNA
Figure 9-44