Fig 17.8 Biosynthesis of amino acids

Table 17.1

A. Alanine, Asparagine, Aspartate, Glutamate and Glutamine

• Pyruvate is the amino-group acceptor in alanine synthesis

Oxaloacetate is the amino-group acceptor in the synthesis of

aspartate

Synthesis of asparagine

B. Serine, Gycine, and Cysteine

• Fig 17.9 Serine is derived from the glycolytic intermediate 3-phosphoglycerate

Fig 17.9 (continued)

(from previous slide)

Fig 17.10 Biosynthesis of glycine

Fig 17.11

• Compounds formedfrom serine and glycine

Fig 17.12

• Cysteine biosynthesis from serine in bacteria, plants

Fig 17.13 Cysteine biosynthesis in mammals

17.5 Synthesis of Essential Amino Acids

• Pathways have largely been determined from studies with bacteria

• Plants are thought to synthesize essential amino acids by similar pathways

D. Tyrosine

Fig 17.15

(continued next slide)