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603 nent, and temples flattened and hollowed into shallow con- cavities. The patient was dozing; lying on the right side, in which he had been recently placed, for his debility pre- vented any effort on his part. The respirations were very low and almost imperceptible, but regular. Pulse 120; small, wiry, and irritable; he opened his eyes without displaying any excitement; the countenance then appeared calm, but wan and ghastly; no expression of anxiety, (in the medical sense); it was that of exhaustion rather than pain; skin of moderate temperature. Pulse of the same character as when he dozed. Tongue dry, red, and inclined to brown ; surface not glazed, but rough, and papillea prominent; no sordes on tongue, teeth, or lips; the latter parched. - In a hollow, faint voice, he stated that he felt no pain, but very weak and exhausted. As his condition required that he should be disturbed as little as possible, I only examined the abdomen, by passing my hand over it, and ascertaining I that it was flat and hollow, and much shrunken, but no irre- i gularity or unusual hardness or tenderness. His mother stated that there were no petechiæ on the surface, nor bed- sores. The bowels had been occasionally irritable from yel- lowish fluid dejection; urine scanty, but clear. It was stated to me that in the first week of the month of September, he had suffered from an accident on the Great Northern Railway; that he became confused in his head, and shortly after had an attack of fever, with delirium; the sur- face of the abdomen being covered with maculae, with a yellowish ochry diarrhosa ; that in about three weeks he became convalescent, and was up and about, but that he had suffered a relapse; and for the last four weeks had been at- tended by the before-named representatives of the Hahne- mannic practice. Mr. Russell informed me-and he obtained his information from the gentleman’s partner-that the treat- ment had been minute quantities of syrup of cherries, and syrup of raspberries, and a tea-spoonful of chicken-broth, diluted with water, three or four times daily. This latter amount of nutriment was confirmed by the mother, who was told that any larger quantity would be detrimental. l had nothing to do with the previous treatment, as it only reached me on hearsay, except the dietary. But the opinion I gave was, that the present condition of the patient was that of exhaustion from want of proper support, rather than as the sequel of fever; and unless a different plan of treatment were adopted the patient must die of inanition. The whole aspect of the patient justified this conclusion. His condition wanted the usual characteristics of the prostrate exhaustion of typhoid fever. The eye and intellect were too clear; there had not been for weeks any stupor-on the contrary, most wearisome and exhausting wakefulness. Of late some wandering, both during the scanty periods of sleep, or rather dozing, and the long waking intervals. Neither the tongue, the pulse, nor the skin, exhibited the indication of fever. Whatever might have been his preceding condition in September, it was very obvious that his present state was the prostration of inanition. This patient reminded me forcibly, only in an exaggerated form, of those cases of exhaustion, that those who have charge of our public hospitals must have repeatedly witnessed, of patients who have struggled through an attack of fever, neglected, and in want and wretchedness, but being found out by some good Samaritan, and being passed into an hospital, have rapidly improved, under simple nutrition and judiciously proportioned stimulants. I urged the imperative necessity of immediately administer- ing cautious quantities-of the simpler forms of nourishment, with small quantities of port-wine freely diluted. I learn that he rapidly convalesced. Mr. Russell did not, however, con- tinue to attend him, but I hear from him that the family feud was compromised by their declining the further attentions of the homoeopathists, and confiding the patient to the- attentive soli- citude of his mother, who had been opposed to the homoeopa- thic practice, and had consulted Mr. Russell. She, guided by the advice we had given her, soon found that there was no death in nutrition, and that port-wine was not quite so poisonous as had been represented to her. I think, Sir, this case forcibly illustrates the evils of this visionary system of practice. So long as the homceopathist has to deal with mere dyspeptics or credulous and easily deluded hypochondriacs, his scheme may amuse the mind, but cannot harm the body; but.in the more -serious and acute forms of disease, it becomes a question of some moment how the public can protect themselves against the serious consequences of so much ignorance. In this case the patient was carried to the very threshold of the grave-a sacrifice to a perverse adherence to a visionary hypothesis,. in spite of the palpable, unmistakeable evidence of a starving man before them. Their daily answer was, " they were waiting for the crisis"! and the only crisis that their views would have recognised would have been the crisis of death. Chester-street, Grosvenor-place, 1851. EPILEPSY AND QUININE. BY W. G. MAXWELL, M.D., Garrison Surgeon, India. THE severest fit of epilepsy can be arrested by a large dose of quinine. The periodicitv also is destroyed by this medi- cine, and (by due attention) the disease cured. CASE.-A tall, stout, well-made labourer (Ryot) was seized with a severe fit of epilepsy at five A.M. I saw him about seven, by accident. He was lying in a dark corner, with an old blanket thrown over him. I was informed he was subject to these fits; that he would continue in them for three days; that nothing was done, except occasionally (if the fits were severe) throwing some cold water over him. I Immediately set about trying what I could do for him. Ammonia, counter-stimulants, blisters, emetics, purgatives, cold, heat, &c., were all tried without the slightest relief. The bowels were freely open involuntarily-faeculent, semi-con- sistent, light colour. Free vomiting of phlegm, rice water, &c. was also going on without the slightest relief. I now thought of trying quinine, as follows: Disulphate of quinine, twenty grains ; aromatic tincture, one ounce ; hot water, three ounces. This was gradually given with much difficulty, (as will easily be imagined,) as hot as possible, in teaspoonfuls at a time. By the time half had been taken there was an evident remission in the severity of the symptoms; and by the time the whole of the draught had been got down the fits had ceased to return. He fell- off to sleep, and slept soundly for three hours; he was well covered up, and perspired most pro- f’usely,--one of the effects of the quinine. Remarks.-It is almost needless for me to point to the im- portance of paying due attention to the power of sol-lunar influence at certain periods, in reference to this disease, as well as to the great exciting cause of irregularity (excess especially) in diet. And as we can control the disease (which necessarily includes its periodicity) at an early period, we shall prevent the almost certain tendency of repeated attacks to terminate in a fatal or incurable organic lesion. India, South Division, 1851. Foreign Department. A S’ubstitute for Mercury in Syphilitic Diseases. M. E. ROBIN has read a paper before the Academy of Sciences of Paris, with the following title,-" On Certain New Agents calculated as Substitutes for Mercury when used as .an Anti-syphilitic Remedy." In former papers, M. Robin had maintained these propositions: - ‘‘ Mercurial- preparations do not act in a peculiar manner when adminis- tered in syphilitic diseases; they merely combine with- the virus and change it into a new or inert compound. Now there are a great many substances which form analogous combinations with organized matter, which substances probably have, like mercury, anti-syphilitic virtues; and it will be found that the agents of this class, which have thus been successfully employed, belong to the .antiseptic division of remedies which act by combining with the noxious princi- ples. In this manner we can understand whence arise the anti-syphilitic properties of arsenical, gold, silver, steel, and antimonial preparations. Hence arises the likelihood of success, if attempts. be made to use such organic substances as the bichromate of potash, or sesquichloride of iron, instead of mercurials." M. Robin induced Dr. Vicenti, of Paris, to try.a few experi- ments with the bichromate of potash to combat syphilis; the salt was employed in three cases with much success, and of these one was marked by very severe secondary symptoms. Fifteen grains of the bichromate were divided into eighty pills, with extract of gentian. One of these was taken night and morning. They agreed pretty well with the stomach, though some opium was necessary to prevent nausea and vomiting. The patient took 240 pills in the space of about three months, and was then quite well of a very intense attack of iritis, accompanied by other syphilitic symptoms, which had almost blinded him. The patient had had an indurated chancre, and had never taken any mercury.
Transcript

603

nent, and temples flattened and hollowed into shallow con-cavities. The patient was dozing; lying on the right side,in which he had been recently placed, for his debility pre-vented any effort on his part. The respirations were verylow and almost imperceptible, but regular. Pulse 120; small,wiry, and irritable; he opened his eyes without displaying anyexcitement; the countenance then appeared calm, but wanand ghastly; no expression of anxiety, (in the medical

sense); it was that of exhaustion rather than pain; skin ofmoderate temperature. Pulse of the same character as whenhe dozed. Tongue dry, red, and inclined to brown ; surfacenot glazed, but rough, and papillea prominent; no sordes ontongue, teeth, or lips; the latter parched. -

In a hollow, faint voice, he stated that he felt no pain, butvery weak and exhausted. As his condition required thathe should be disturbed as little as possible, I only examinedthe abdomen, by passing my hand over it, and ascertaining Ithat it was flat and hollow, and much shrunken, but no irre- i

gularity or unusual hardness or tenderness. His motherstated that there were no petechiæ on the surface, nor bed-sores. The bowels had been occasionally irritable from yel-lowish fluid dejection; urine scanty, but clear.

It was stated to me that in the first week of the month ofSeptember, he had suffered from an accident on the GreatNorthern Railway; that he became confused in his head, andshortly after had an attack of fever, with delirium; the sur-face of the abdomen being covered with maculae, with ayellowish ochry diarrhosa ; that in about three weeks hebecame convalescent, and was up and about, but that he hadsuffered a relapse; and for the last four weeks had been at-tended by the before-named representatives of the Hahne-mannic practice. Mr. Russell informed me-and he obtainedhis information from the gentleman’s partner-that the treat-ment had been minute quantities of syrup of cherries, andsyrup of raspberries, and a tea-spoonful of chicken-broth,diluted with water, three or four times daily. This latteramount of nutriment was confirmed by the mother, who wastold that any larger quantity would be detrimental.

l had nothing to do with the previous treatment, as it onlyreached me on hearsay, except the dietary. But the opinionI gave was, that the present condition of the patient was thatof exhaustion from want of proper support, rather than as thesequel of fever; and unless a different plan of treatment wereadopted the patient must die of inanition. The whole aspectof the patient justified this conclusion. His condition wantedthe usual characteristics of the prostrate exhaustion of typhoidfever. The eye and intellect were too clear; there had notbeen for weeks any stupor-on the contrary, most wearisomeand exhausting wakefulness. Of late some wandering, bothduring the scanty periods of sleep, or rather dozing, and thelong waking intervals. Neither the tongue, the pulse, nor theskin, exhibited the indication of fever. Whatever might havebeen his preceding condition in September, it was very obviousthat his present state was the prostration of inanition.

This patient reminded me forcibly, only in an exaggeratedform, of those cases of exhaustion, that those who have chargeof our public hospitals must have repeatedly witnessed, ofpatients who have struggled through an attack of fever,neglected, and in want and wretchedness, but being found outby some good Samaritan, and being passed into an hospital,have rapidly improved, under simple nutrition and judiciouslyproportioned stimulants.

I urged the imperative necessity of immediately administer-ing cautious quantities-of the simpler forms of nourishment,with small quantities of port-wine freely diluted. I learn thathe rapidly convalesced. Mr. Russell did not, however, con-tinue to attend him, but I hear from him that the family feud

was compromised by their declining the further attentions of thehomoeopathists, and confiding the patient to the- attentive soli-citude of his mother, who had been opposed to the homoeopa-

thic practice, and had consulted Mr. Russell. She, guided bythe advice we had given her, soon found that there was nodeath in nutrition, and that port-wine was not quite so

poisonous as had been represented to her.I think, Sir, this case forcibly illustrates the evils of this

visionary system of practice. So long as the homceopathist hasto deal with mere dyspeptics or credulous and easily deludedhypochondriacs, his scheme may amuse the mind, but cannotharm the body; but.in the more -serious and acute forms ofdisease, it becomes a question of some moment how the publiccan protect themselves against the serious consequences of somuch ignorance.

In this case the patient was carried to the very threshold ofthe grave-a sacrifice to a perverse adherence to a visionary

hypothesis,. in spite of the palpable, unmistakeable evidence ofa starving man before them. Their daily answer was, " theywere waiting for the crisis"! and the only crisis that their viewswould have recognised would have been the crisis of death.

Chester-street, Grosvenor-place, 1851.

EPILEPSY AND QUININE.BY W. G. MAXWELL, M.D., Garrison Surgeon, India.

THE severest fit of epilepsy can be arrested by a large doseof quinine. The periodicitv also is destroyed by this medi-cine, and (by due attention) the disease cured.

’ CASE.-A tall, stout, well-made labourer (Ryot) was seizedwith a severe fit of epilepsy at five A.M. I saw him about seven,by accident. He was lying in a dark corner, with an oldblanket thrown over him. I was informed he was subject tothese fits; that he would continue in them for three days; thatnothing was done, except occasionally (if the fits were severe)throwing some cold water over him. I Immediately set abouttrying what I could do for him.Ammonia, counter-stimulants, blisters, emetics, purgatives,

cold, heat, &c., were all tried without the slightest relief. Thebowels were freely open involuntarily-faeculent, semi-con-sistent, light colour. Free vomiting of phlegm, rice water, &c.was also going on without the slightest relief. I now thoughtof trying quinine, as follows: Disulphate of quinine, twentygrains ; aromatic tincture, one ounce ; hot water, threeounces. This was gradually given with much difficulty, (aswill easily be imagined,) as hot as possible, in teaspoonfuls at atime. By the time half had been taken there was an

evident remission in the severity of the symptoms; and by thetime the whole of the draught had been got down the fits hadceased to return. He fell- off to sleep, and slept soundly forthree hours; he was well covered up, and perspired most pro-f’usely,--one of the effects of the quinine.Remarks.-It is almost needless for me to point to the im-

portance of paying due attention to the power of sol-lunarinfluence at certain periods, in reference to this disease, aswell as to the great exciting cause of irregularity (excessespecially) in diet. And as we can control the disease(which necessarily includes its periodicity) at an early period,we shall prevent the almost certain tendency of repeatedattacks to terminate in a fatal or incurable organic lesion.

India, South Division, 1851.

Foreign Department.A S’ubstitute for Mercury in Syphilitic Diseases.

M. E. ROBIN has read a paper before the Academy ofSciences of Paris, with the following title,-" On CertainNew Agents calculated as Substitutes for Mercury whenused as .an Anti-syphilitic Remedy." In former papers,M. Robin had maintained these propositions: - ‘‘ Mercurial-preparations do not act in a peculiar manner when adminis-tered in syphilitic diseases; they merely combine with- thevirus and change it into a new or inert compound. Nowthere are a great many substances which form analogouscombinations with organized matter, which substancesprobably have, like mercury, anti-syphilitic virtues; and it willbe found that the agents of this class, which have thus beensuccessfully employed, belong to the .antiseptic division ofremedies which act by combining with the noxious princi-ples. In this manner we can understand whence arise theanti-syphilitic properties of arsenical, gold, silver, steel, andantimonial preparations. Hence arises the likelihood ofsuccess, if attempts. be made to use such organic substancesas the bichromate of potash, or sesquichloride of iron, insteadof mercurials."M. Robin induced Dr. Vicenti, of Paris, to try.a few experi-

ments with the bichromate of potash to combat syphilis; thesalt was employed in three cases with much success, and ofthese one was marked by very severe secondary symptoms.Fifteen grains of the bichromate were divided into eightypills, with extract of gentian. One of these was taken nightand morning. They agreed pretty well with the stomach,though some opium was necessary to prevent nausea andvomiting. The patient took 240 pills in the space of aboutthree months, and was then quite well of a very intenseattack of iritis, accompanied by other syphilitic symptoms,which had almost blinded him. The patient had had anindurated chancre, and had never taken any mercury.

604

Generation of Sugar in a Dtbilitated Condition.M. ALVARO REYNOSO lately maintained, before the Academy

of Sciences of Paris, that there exists a connexion betweenthe phenomena of respiration, and the presence of sugar inthe urine. He therefore considers that all the substanceswhich retard the act of breathing, and thus diminish theamount of red blood in the lung, may be looked upon as causingsugar to be generated, and thrown off by the urine. Ac-cording then to M. Reynoso’s views, we ought to find sugarin the urine of persons who are taking lowering remedies. Totest the truth of this position the author examined the urineof persons taking bichloride, iodide, or sulphuret of mercury,antimonial salts, opium, or sulphate of quinine, and dis-covered sugar in that secretion. He intends makingexperiments in order to discover in how much time afterthese remedies are left off, the sugar disappears from theurine; and whether the absence of the sugar and the completediscontiuance of the remedy are coincident circumstances.

Strangulated Hernia Reduced during Vomiting.L’Union Medicale mentions that Dr. Kuttlinger, ofErIangen,

in Germany, tried the taxis upon a woman sixty-four years ofage, whose crural hernia was strangulated, but without success.The patient was soon attacked with vomiting, and whilst shewas making efforts, Dr. Kuttlinger seized the tumour, pressedit with some force, and succeeded in reducing it in the verymidst of the straining. Three months afterwards strangulationoccurred again, the taxis was tried in vain, and reduction waseffected exactly in the same manner as before.

Dr. Lebert an the Structure of Cataract.Dr. LEBERT stated, a short time ago, before the Surgical

Society of Paris, that he had no faith in certain ammoniacalpreparations which had been supposed capable of producingresolution in cases of incipient cataract. He examined crys-talline lenses somewhat altered in structure, and found veryimportant changes. In hard cataract, for instance, there wasan opaque, granular substance interposed between the lamellaeof the lens; this substance is beyond the action of the absorb-ents, as the lamellae themselves are horny and atrophied. Insoft cataract there is seen in the crystalline cells an effusion of

- a milky fluid, and in this fluid crystals of cholestearine can bedistinguished, the lamellse being at the same time softened andhypertrophied. None but a surgical treatment can in suchcases be followed by a successful result. It was shown duringthe discussion that those cases which were benefited byGondret’s ammoniacal ointment, were not cases of incipientcataract, but instances of an early stage of amaurosis.

Accusation of Mala-praxis in France.A case was lately tried at Montbrison, in France, which

shows how unjustly the friends of a patient may burden themedical attendant with the untoward results of his treatment.Dr. POYET was charged by the widow of a man who had diedafter fracture of the femur-1, with refusing to call in anothersurgeon; 2, with having announced consolidation during thetreatment; 3, with not having acquainted the family with theserious nature of the case. Dr. Poyet, however, brought suffi-cient evidence to show that the fracture was very oblique, andthat the want of success was entirely owing to the negligenceof the patient’s friends. He obtained a verdict in his favour,£12 for his attendance, and the plaintiff was charged with thecosts.

Hospital Reports.NEWCASTLE-UPON-TYNE INFIRMARY.

CASES OPERATED ON BY SIR JOHN FIFE.

(Reported by THOMAS JOSEPH TURNBULL, Dresser.)

Case of Lithotomy.CASE 1.—T. T-, aged thirteen, from the county of North-

umberland, admitted Nov. 7th, with symptoms of calculusvesicæ. He had been ill for nearly ten years, presentingsymptoms of nephritis calculosa. A month previous to his admit-tance into the hospital, a calculus descended into the bladder.On the introduction of a sound, a stone was distinctly found

lodged in the fundus of the bladder. The immediate removalof this stone was resolved upon. The grooved staff used bySir John Fife was less curved than usual. The operation wasdone with great gentleness in less than two minutes, eachstep of the operation effected in the usual manner, and after-wards an elastic gum tube was introduced through the woundinto the bladder. A piece of lint was pressed in on the rightside of it, which arrested the bleeding of a small artery.l4th.-The tube and lint came out this morning, and the

boy seems convalescent.The irritability of this patient was so extraordinary as to

discourage all idea of lithotrity. The boy was quite uncon-scious of the operation, the effect of chloroform being com-plete.plete. Malignant Tumour of the Heel.

CASE 2.-T. T--, aged seventy-five, married, and a native ofWarkworth, in the county of Northumberland, was admittedNov. 6th, with a large malignant fungous tumour of the rightheel; it covers the outer and posterior parts of the heel. A wartmade its appearance five years ago on the seat of disease,which speedily took on ulceration, and gradually attained itspresent size. There is excessive pain, profuse discharge of asanious nature, and a foul cancerous smell. The patient re-markably healthy for his age; his pulse moderate. He hadbeen under various treatment for some time, and the removalof the limb appeared the only chance of saving the old man’slife.

Sir John Fife amputated close below the knee by the usualflap operation. The remarkable circumstance in this case wasthe diseased state of the coats of the arteries, which wereossified, brittle, and friable, so that they gave way and werecut through by every ordinary ligature; larger ones werethen used, and even these were not drawn tight-in this wayonly could the haemorrhage be arrested. The patient, sincethe operation, is doing well, and on the 15th the stump wasdressed, and found united by the first intention.

An Un-united Fracture of the Femur.CASE 3.-P. R-, aged twenty-nine, pitman, married, and a

native of Coxhoe, was admitted into the hospital on Nov. 6th,with an un-united fracture of the right femur at its middle;it was broken thirty-four weeks ago by a fall of a stone fromthe roof of a pit: he lay three months in bed.

Sir John Fife pressed a large, strong needle (such as usedafter autopsies) on the inside of the rectus muscle, till itreached the middle of the thigh, between the ends of the bone;he then moved the point freely both transversely and verti-cally, grating it against the ends of the bones. A piece of ad-hesive plaster was placed on the puncture, the patient put tobed, and the limb secured on Dessault’s splint. Ordered totake, iodide of potassium, five grains; carbonate of potassium,ten grains, twice a day.

Reviews and Notices of Books.

An Inquiry into the Proper Clas8ifcation and Treatment ofCriminal Lunatics. By J. C. BUCKNILL, M.B., Superin-tendent of the Devon County Asylum. Large 8vo., pp. 56.tendent of the Devon County Asylum. Large 8vo., pp. 56.London, 1851.IN consequence of the movement now being made to

provide a suitable asylum for criminal lunatics, Dr. Buck-nill, acting under the instructions of the visiting justicesof the asylum to which he is attached, has addressedhis views on the subject founded evidently on experience,to the chairman of that board, and subsequently commu-nicated them to the profession and the public gene-rally, in the form of the forcibly and well-written pamphletnow before us. Dr. Bucknill’s object seems to be, to preventthe inconveniences and injustice which must result to manyso-called criminal lunatics, if removed to a central asylum.The individuals thus excepted are those, whose insanity beingestablished beyond doubt, must render them absolutely inno-cent of crime, whilst their conduct and demeanour are suchas to justify their detention, without injury to themselves ortheir fellow-patients, in the county asylums, in which they areat present confined. Dr. Bucknill’s arguments on this point

illustrated by several cases) deserve the fullest consideration.


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