Front MatterSource: Proceedings of the National Academy of Sciences of the United States of America,Vol. 86, No. 3 (Feb. 1, 1989), pp. iii-viiPublished by: National Academy of SciencesStable URL: http://www.jstor.org/stable/33277 .

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Proceedings OF THE

National Academy of Sclences

OF THE UNITED STATES OF AMERICA

February 1989 Volume 86, Number 3 pp. 755-1104

Table of Contents

CONDENSED INFORMATION FOR CONTRIBUTORS

AUTHOR INDEX ix

Review Human immunodeficiency virus and acquired immunodeficiency syndrome: Peter H. Duesberg 755

Correlation but not causation

Physical Sciences

CHEMISTRY

a-Helix and mixed 31o/a-helix in cocrystallized conformers of Isabella L. Karle, Judith L. 765 Boc-Aib-Val-Aib-Aib-Val-Val-Val-Aib-VaI-Aib-OMe Flippen-Anderson, Kuchibhotla Uma,

Hemalatha Balaram, and Padmanabhan Balaram

Structural characterization of toxic cyclic peptides from blue-green algae by Thaiya Krishnamurthy, Linda 770 tandem mass spectrometry Szafraniec, Donald F. Hunt, Jeffrey

Shabanowitz, John R. Yates III, Charles R. Hauer, Wayne W. Carmichael, Olav Skulberg, Geoffrey A. Codd, and Stephen Missler

MATHEMATICS

Young-Capelli symmetrizers in superalgebras Andrea Brini and Antonio G. B. Teolis 775

111

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Contents

Biological Sciences

BIOCHEMISTRY

Inhibitor of hematopoietic pluripotent stem cell proliferation: Purification and Maryse Lenfant, Joanna 779 determination of its structure Wdzieczak-Bakala, Eric Guittet,

Jean-Claude Prome, Dominique Sotty, and Emilia Frindel

Altered sensitivity of system A amino acid transport to ouabain in normal and Kirk J. Leister, Mark A. Schenerman, 783 transformed C3H-10T1/2 cells during the cell cycle and Efraim Racker

Skeletal muscle proteasome can degrade proteins in an ATP-dependent process James Driscoll and Alfred L. Goldberg 787 that does not require ubiquitin

Expression of &aminolevulinate synthase in avian cells: Separate genes encode Robert D. Riddle, Masayuki Yamamoto, 792 erythroid-specific and nonspecific isozymes and James Douglas Engel

DNA binding specificity of the Arc and Mnt repressors is determined by a Kendall L. Knight and Robert T. Sauer 797 short region of N-terminal residues

Purification and characterization of a newly identified growth factor specific for Jeffrey S. Rubin, Hiroyuki Osada, Paul 802 epithelial cells W. Finch, William G. Taylor, Stuart

Rudikoff, and Stuart A. Aaronson Activity of purified biosynthetic proteinase of human immunodeficiency virus Hans-Georg Krausslich, Richard H. 807

on natural substrates and synthetic peptides Ingraham, Mark T. Skoog, Eckard Wimmer, Peter V. Pallai, and Carol A. Carter

Phosphorylation at threonine-654 is not required for negative regulation of the BethAnn Friedman, John van 812 epidermal growth factor receptor by non-phorbol tumor promoters Amsterdam, Hirota Fujiki, and Marsha

Rich Rosner Identification of resonances from an oncogenic activating locus of human Sharon Campbell Burk, Mary Z. 817

N-RAS-encoded p21 protein using isotope-edited NMR Papastavros, Frank McCormick, and Alfred G. Redfield

Bioassay for trans-activation using purified human immunodeficiency virus Reiner Gentz, Chein-Hwa Chen, and 821 tat-encoded protein: Trans-activation requires mRNA synthesis Craig A. Rosen

Cytosolic components of the respiratory burst oxidase: Resolution of four John T. Curnette, Patricia J. Scott, and 825 components, two of which are missing in complementing types of chronic Laura A. Mayo granulomatous disease

Secondary a factor controls transcription of flagellar and chemotaxis genes in David N. Arnosti and Michael J. 830 Escherichia coli Chamberlin

Expression of human ferredoxin and assembly of the [2Fe-2S] center in Vincent M. Coghlan and Larry E. 835 Escherichia coli Vickery

A single DNA response element can confer inducibility by both a- and Laurence E. Reid, Adrian H. Brasnett, 840 ,y-interferons Christopher S. Gilbert, Andrew C. G.

Porter, Dirk R. Gewert, George R. Stark, and Ian M. Kerr

Structural-transitions in crystals of native aspartate carbamoyltransferase J. Eric Gouaux and William N. 845 Lipscomb

Localization to the inner surface of the cytoplasmic membrane by Bijan K. Ghosh, Kristin Owens, Rafael 849 immunoelectron microscopy of enzyme I of the phosphoenolpyruvate:sugar Pietri, and Alan Peterkofsky phosphotransferase system of Escherichia coli

Identification of androgen receptors in normal human osteoblast-like cells Douglas S. Colvard, Erik F. Eriksen, 854 Philip E. Keeting, Elizabeth M. Wilson, Dennis B. Lubahn, Frank S. French, B. Lawrence Riggs, and Thomas C. Spelsberg

Phosphorylation of RAS1 and RAS2 proteins in Saccharomyces cerevisiae Alexander R. Cobitz, Elizabeth H. Yim, 858 William R. Brown, Charles M. Perou, and Fuyuhiko Tamanoi

Estrogen receptor selectively binds the "scoding strand" of an estrogen Deborah A. Lannigan and Angelo C. 863 responsive element Notides

Iloprost-induced translocation of a 23-kDa protein that is recognized Luis Molina y Vedia and Eduardo G. 868 by a Gsat antiserum Lapetina

Strand specificity of DNA unwinding by RecBCD enzyme Gary Braedt and Gerald R. Smith 871 Binding and transcription of relaxed DNA templates by fractions of maize David Zaitlin, Jim Hu, and Lawrence 876

chloroplast extracts Bogorad

iv

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Contents

BIOPHYSICS

Inhibition of growth of nonbasal planes in ice by fish antifreezes James A. Raymond, Peter Wilson, and 881 Arthur L. DeVries

BOTANY

Effect of mutations on the binding and translocation functions of a chloroplast Bernd Reiss, Catherine C. Wasmann, 886 transit peptide Jeff Schell, and Hans J. Bohnert

Functional evidence for an auxin receptor at the plasmalemma of tobacco Helene Barbier-Brygoo, Genevieve 891 mesophyll protoplasts Ephritikhine, Dieter Klambt, Michel

Ghislain, and Jean Guern Isolation of a complementary DNA encoding a chitinase with structural J. P. Metraux, William Burkhart, Mary 896

homology to a bifunctional lysozyme/chitinase Moyer, Sandra Dincher, Wayne Middlesteadt, Shericca Williams, George Payne, Michael Carnes, and John Ryals

CELL BIOLOGY

Thrombin treatment induces rapid changes in tyrosine phosphorylation in Andy Golden and Joan S. Brugge 901 platelets

Specific postendocytic proteolysis of apolipoprotein B in oocytes does not Johannes Nimpf, Markus Radosavljevic, 906 abolish receptor recognition and Wolfgang J. Schneider

Induction of class I major histocompatibility complex antigen expression by N. J. C. King, .L. E. Maxwell, and 911 West Nile virus on y interferon-refractory early murine trophoblast cells A. M. Kesson

Cloned endothelial cells from fetal bovine bone Elizabeth A. Streeten, Richard Ornberg, 916 Francesco Curcio, Kazushige Sakaguchi, Stephen Marx, Gerald D. Aurbach, and Maria Luisa Brandi

Early reversible induction of leukotriene synthesis in chicken myelomonocytic Andreas J. R. Habenicht, Matthias 921 cells transformed by a temperature-sensitive mutant of avian leukemia Goerig, Dietrich E. R. Rothe, virus E26 Elisabeth Specht, Reinhard Ziegler,

John A. Glomset, and Thomas Graf Evidence that autophosphorylation of solubilized receptors for epidermal A. M. Honegger, R. M. Kris, A. Ullrich, 925

growth factor is mediated by intermolecular cross-phosphorylation and J. Schlessinger Species distribution of a phosphoprotein (parafusin) involved in exocytosis B. H. Satir, T. Hamasaki, M. Reichman, 930

and T. J. Murtaugh

DEVELOPMENTAL BIOLOGY

Synthesis and characterization of a model extracellular matrix that induces I. V. Yannas, E. Lee, D. P. Orgill, 933 partial regeneration of adult mammalian skin E. M. Skrabut, and G. F. Murphy

Growing and developing Dictyostelium cells express different ras genes Stephen M. Robbins, Jeffrey G. 938 Williams, Keith A. Jermyn, George B. Spiegelman, and Gerald Weeks

GENETICS

Genetic characterization of FLA, the cat major histocompatibility complex Cheryl Winkler, Alan Schultz, Stanley 943 Cevario, and Stephen O'Brien

A major insertion accounts for a significant proportion of mutations underlying Sylvie Langlois, Samir Deeb, John D. 948 human lipoprotein lipase deficiency Brunzell, John J. Kastelein, and

Michael R. Hayden Identification of the structural mutation responsible for the dibucaine-resistant Mary C. McGuire, Christine P. 953

(atypical) variant form of human serum cholinesterase Nogueira, Cynthia F. Bartels, Harold Lightstone, Amitav Hajra, Abraham F. L. Van der Spek, Oksana Lockridge, and Bert N. La Du

Nucleotide substitution at major histocompatibility complex class II loci: Austin L. Hughes and Masatoshi Nei 958 Evidence for overdominant selection

A plasmid-encoded regulatory gene, ins, required for expression of the CS1 Judy Caron, Lisa M. Coffield, and 963 and CS2 adhesions of enterotoxigenic Escherichia coli June R. Scott

PrlA is important for the translocation of exported proteins across the Kristina L. Bieker and Thomas J. 968 cytoplasmic membrane of Escherichia coli Silhavy

v

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Contents Lack of positional requirements for autonomously replicating sequence Raymund J. Wellinger and Virginia A. 973

elements on artificial yeast chromosomes Zakian Isolation of two alleles of the b locus of Ustilago maydis J. W. Kronstad and S. A. Leong 978 Molecular patterns of X chromosome-linked color vision genes among 134 men Margaret Drummond-Borg, Samir S. 983

of European ancestry Deeb, and Arno G. Motulsky T-cell receptor V< and Cc, alleles associated with multiple sclerosis and Jorge R. Oksenberg, Martina Sherritt, 988

myasthenia gravis Ann B. Begovich, Henry A. Erlich, Claude C. Bernard, Luigi L. Cavalli-Sforza, and Lawrence Steinman

Milk and fat production in dairy cattle influenced by advanced subclinical Ming-Che Wu, Roger D. Shanks, and 993 bovine leukemia virus infection Harris A. Lewin

Asbestos fibers mediate transformation of monkey cells by exogenous Jill D. Appel, Thomas M. Fasy, D. Stave 997 plasmid DNA (Correction) Kohtz, Jhumku D. Kohtz, and Edward

M. Johnson A cDNA encoding tyrosinase-related protein maps to the brown locus Ian J. Jackson 997

in mouse (Correction)

IMMUNOLOGY

A secreted form of the human lymphocyte cell surface molecule CD8 arises Patricia Giblin, Jeffrey A. Ledbetter, and 998 from alternative splicing Paula Kavathas

Alternative splicing of HLA-DQB transcripts and secretion of HLA-DQ Paola Briata, Susan F. Radka, Silva 1003 ,-chain proteins: Allelic polymorphism in splicing and Sartoris, and Janes S. Lee polyadenylylation sites

Cardiac allograft survival in mice treated with IL-2-PE40 Haya Lorberboum-Galski, Leslie V. 1008 Barrett, Robert L. Kirkman, Masato Ogata, Mark C. Willingham, David J. FitzGerald, and Ira Pastan

Human FcyRIII: Cloning, expression, and identification of the chromosomal Gary A. Peltz, Howard 0. Grundy, 1013 locus of two Fc receptors for IgG Roger V. Lebo, Hans Yssel, Gregory

S. Barsh, and Kevin W. Moore Major histocompatibility complex class I-specific cytolytic T cells, derived Scott Wadsworth, Katsuyuki Yui, and 1018

from gld mice, lacking Thy-1, CD4, and CD8 Mark I. Greene T-cell receptor 6-chain diversity in peripheral lymphocytes Michael J. Lacy, Leslie Klis McNeil, 1023

Matthew E. Roth, and David M. Kranz

Mutational analysis of the HLA-DQ3.2 insulin-dependent diabetes mellitus William W. Kwok, Carla Lotshaw, Eric 1027 susceptibility gene C. B. Milner, Nan Knitter-Jack, and

Gerald T. Nepom Creation of H-2 class I epitopes using synthetic peptides: Recognition of Clifford A. Olson, Lynn C. Williams, 1031

alloreactive cytotoxic T lymphocytes Elizabeth McLaughlin-Taylor, and Minnie McMillan

MEDICAL SCIENCES

Thrombus imaging in a primate model with antibodies specific for an external Theresa M. Palabrica, Barbara C. Furie, 1036 membrane protein of activated platelets Marvin A. Konstam, Mark J.

Aronovitz, Raymond Connolly, Barbara A. Brockway, Karen L. Ramberg, and Bruce Furie

A 5' splice-region G -. C mutation in exon 1 of the human P-globin gene Michel Vidaud, Renata Gattoni, James 1041 inhibits pre-mRNA splicing: A mechanism for P3-thalassemia Stevenin, Dominique Vidaud, Serge

Amselem, Jemni Chibani, Jean Rosa, and Michel Goossens

A role for endothelial cell lipoxygenase in the oxidative modification of low S. Parthasarathy, E. Wieland, and D. 1046 density lipoprotein Steinberg

2-Acetylpyridine 5-[(dimethylamino)thiocarbonyl]-thiocarbonohydrazone Thomas Spector, Joan A. Harrington, 1051 (A111OU), a potent inactivator of ribonucleotide reductases of herpes Robert W. Morrison, Jr., Catherine U. simplex and varicella-zoster viruses and a potentiator of acyclovir Lambe, Donald J. Nelson, Devron R.

Averett, Karen Biron, and Phillip A. Furman

Platelet-derived growth factor synthesis in mesangial cells: Induction by Bernard J. Silver, Fatima E. Jaffer, and 1056 multiple peptide mitogens Hanna E. Abboud

Vl

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Contents

MICROBIOLOGY

Growth restriction of influenza A virus by M2 protein antibody is genetically Suzanne L. Zebedee and Robert A. 1061 linked to the M1 protein Lamb

NEUROBIOLOGY

Protooncogene expression identifies a transient columnar organization of the Janice G. Johnston and Derek van der 1066 forebrain within the late embryonic ventricular zone Kooy

Organization of corticocortical connections in human visual cortex Andreas Burkhalter and Kerry L. 1071 Bernardo

Process elimination underlies ontogenetic change in the distribution of callosal Leo M. Chalupa and Herbert P. 1076 projection neurons in the postcentral gyrus of the fetal rhesus monkey Killackey

Partial purification and characterization of a membrane-derived factor Joshua E. Adler, Leonard S. Schleifer, 1080 regulating neurotransmitter phenotypic expression and Ira B. Black

Nonanesthetic alcohols dissolve in synaptic membranes without perturbing K. W. Miller, L. L. Firestone, J. K. 1084 their lipids Alifimoff, and P. Streicher

Topology of cell adhesion molecules Joseph W. Becker, Harold P. Erickson, 1088 Stanley Hoffman, Bruce A. Cunningham, and Gerald M. Edelman

Individual microglia move rapidly and directly to nerve lesions in the leech Ellen McGlade-McCulloh, Alice M. 1093 central nervous system Morrissey, Fernando Norona, and

Kenneth J. Muller Retinal melatonin is metabolized within the eye of Xenopus Iaevis Gregory M. Cahill and Joseph C. 1098

Besharse Immortalization of mouse neural precursor cells by the c-myc P. F. Bartlett, H. H. Reid, K. A. Bailey, 1103

oncogene (Correction) and 0. Bernard

*i

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