Front Matter Source: Proceedings of the National Academy of Sciences of the United States of America, Vol. 93, No. 12 (Jun. 11, 1996), pp. i-viii Published by: National Academy of Sciences Stable URL: http://www.jstor.org/stable/39603 . Accessed: 07/05/2014 16:19 Your use of the JSTOR archive indicates your acceptance of the Terms & Conditions of Use, available at . http://www.jstor.org/page/info/about/policies/terms.jsp . JSTOR is a not-for-profit service that helps scholars, researchers, and students discover, use, and build upon a wide range of content in a trusted digital archive. We use information technology and tools to increase productivity and facilitate new forms of scholarship. For more information about JSTOR, please contact [email protected]. . National Academy of Sciences is collaborating with JSTOR to digitize, preserve and extend access to Proceedings of the National Academy of Sciences of the United States of America. http://www.jstor.org This content downloaded from 169.229.32.136 on Wed, 7 May 2014 16:19:26 PM All use subject to JSTOR Terms and Conditions
Transcript
Front MatterSource: Proceedings of the National Academy of Sciences of the United States of America,Vol. 93, No. 12 (Jun. 11, 1996), pp. i-viiiPublished by: National Academy of SciencesStable URL: http://www.jstor.org/stable/39603 .
Accessed: 07/05/2014 16:19
Your use of the JSTOR archive indicates your acceptance of the Terms & Conditions of Use, available at .http://www.jstor.org/page/info/about/policies/terms.jsp
.JSTOR is a not-for-profit service that helps scholars, researchers, and students discover, use, and build upon a wide range ofcontent in a trusted digital archive. We use information technology and tools to increase productivity and facilitate new formsof scholarship. For more information about JSTOR, please contact [email protected].
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ii Information for Contributors Proc. Natl. Acad. Sci. USA 93 (1996)
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Modifications of RNA processing modulate the 5693-5698 expression of hemoglobin genes
Panagoula Kollia, Eitan Fibach, Sonia M. Najjar, Alan N. Schechter, and Constance Tom Noguchi
Activation and phosphorylation of a pleckstrin 5699-5704 homology domain containing protein kinase (RAC-PK/PKB) promoted by serum and protein phosphatase inhibitors
Mirjana Andjelkovic, Teresa Jakubowicz, Peter Cron, Xiu-Fen Ming, Jeung-Whan Han, and Brian A. Hemmings
A gain-of-function of an amyotrophic lateral 5709-5714 sclerosis-associated Cu,Zn-superoxide dismutase mutant: An enhancement of free radical formation due to a decrease in Km for hydrogen peroxide
Moon Bin Yim, Jung-Hoon Kang, Hyung-Soon Yim, Hahn-Shik Kwak, P. Boon Chock, and Earl R. Stadtman
Msn2p, a zinc finger DNA-binding protein, is the 5777-5782 transcriptional activator of the multistress response in Saccharomyces cerevisiae
Anthony P. Schmitt and Kevin McEntee
Purification of the Drosophila RNA polymerase II 5788-5792 general transcription factors
Richard J. Austin and Mark D. Biggin
HslV-HslU: A novel ATP-dependent protease 5808-5813 complex in Escherichia coli related to the eukaryotic proteasome
Markus Rohrwild, Olivier Coux, H.-C. Huang, Richard P. Moerschell, Soon Ji Yoo, Jae Hong Seol, Chin Ha Chung, and Alfred L. Goldberg
Activating transcription from single stranded DNA 5830-5835 Takeshi Tomonaga and David Levens
Cloning of a novel estrogen receptor expressed in rat 5925-5930 prostate and ovary
George G. J. M. Kuiper, Eva Enmark, Markku Pelto-Huikko, Stefan Nilsson, and Jan-Ake Gustafsson
Leukotriene A4 hydrolase: Protection from 5931-5935 mechanism-based inactivation by mutation of tyrosine-378
Martin J. Mueller, Martina Blomster, Udo C. T. Oppermann, Hans Jornvall, Bengt Samuelsson, and Jesper Z. Haeggstr6m
Structure and conformational changes of DNA 5936-5940 topoisomerase II visualized by electron microscopy
Patrick Schultz, St6phane Olland, Pierre Oudet, and Ronald Hancock
Modulation of growth factor receptor function by 5947-5952 isoform heterodimerization
Wan-Pin Chang and Charles V. Clevenger
A tyrosine kinase profile of prostate carcinoma 5958-5962 Dan Robinson, Feng He, Tom Pretlow, and Hsing-Jien Kung
Molecular cloning of the Golgi apparatus uridine 5963-5968 diphosphate-N-acetylglucosamine transporter from Kluyveromyces lactis
Claudia Abeijon, Phillips W. Robbins, and Carlos B. Hirschberg
Functional expression of mouse Mdrl in an outer 5969-5974 membrane permeability mutant of Escherichia coli
Oded Beja and Eitan Bibi
Kinetics of self-assembling microtubules: An "inverse 5975-5979 problem" in biochemistry
Henrik Flyvbjerg, Elmar Jobs, and Stanislas Leibler
Molecular cloning of a phosphotyrosine-independent 5991-5995 ligand of the p56lck SH2 domain
Insil Joung, Jack L. Strominger, and Jaekyoon Shin
A new endogenous natriuretic factor: LLU-a 6002-6007 William J. Wechter, Darko Kantoci, E. David Murray, Jr., Derin C. D'Amico, Michael E. Jung, and Wen-Hui Wang
Suppression subtractive hybridization: A method for 6025-6030 generating differentially regulated or tissue-specific cDNA probes and libraries
Luda Diatchenko, Yun-Fai Chris Lau, Aaron P. Campbell, Alex Chenchik, Fauzia Moqadam, Betty Huang, Sergey Lukyanov, Konstantin Lukyanov, Nadya Gurskaya, Eugene D. Sverdlov, and Paul D. Siebert
A specific protein carboxyl methylesterase that 6043-6047 demethylates phosphoprotein phosphatase 2A in bovine brain
Jookyung Lee, Ying Chen, Tatiana Tolstykh, and Jeff Stock
Different cleavage sites are aligned differently in the 6085-6090 active site of Ml RNA, the catalytic subunit of Escherichia coli RNase P
Joanna Kufel and Leif A. Kirsebom
Selenocysteine, identified as the penultimate 6146-6151 C-terminal residue in human T-cell thioredoxin reductase, corresponds to TGA in the human placental gene
Vadim N. Gladyshev, Kuan-Teh Jeang, and Thressa C. Stadtman
Introduction of asymmetry in the naturally symmetric 6175-6180 restriction endonuclease EcoRV to investigate intersubunit communication in the homodimeric protein
Frank Stahl, Wolfgang Wende, Albert Jeltsch, and Alfred Pingoud
Subunit cleavage of mosquito pro-vitellogenin by a 6186-6190 subtilisin-like convertase
Jeng-Shong Chen and Alexander S. Raikhel
BIOPHYSICS
Miniature endplate current rise times <100 ,ts from 5747-5752 improved dual recordings can be modeled with passive acetylcholine diffusion from a synaptic vesicle
Joel R. Stiles, Dirk Van Helden, Thomas M. Bartol, Jr., Edwin E. Salpeter, and Miriam M. Salpeter
iv
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Contents Direct observation of fast protein folding: The initial 5759-5764 collapse of apomyoglobin
R. M. Ballew, J. Sabelko, and M. Gruebele
Global properties of the mapping between local amino 5814-5818 acid sequence and local structure in proteins
Karen F. Han and David Baker
Voltage gating and permeation in a gap 5836-5841 junction hemichannel
E. Brady Trexler, Michael V. L. Bennett, Thaddeus A. Bargiello, and Vytas K. Verselis
Conformational trapping in a membrane environment: 5872-5876 A regulatory mechanism for protein activity?
S. Arumugam, S. Pascal, C. L. North, W. Hu, K.-C. Lee, M. Cotten, R. R. Ketchem, F. Xu, M. Brenneman, F. Kovacs, F. Tian, A. Wang, S. Huo, and T. A. Cross
Calcium-dependent oligonucleotide antagonists 5883-5887 specific for L-selectin
Dan O'Connell, Andrea Koenig, Susan Jennings, Brian Hicke, Hui-Ling Han, Tim Fitzwater, Ying-Fon Chang, Nissi Varki, David Parma, and Ajit Varki
G1 arrest and down-regulation of cyclin 5941-5946 E/cyclin-dependent kinase 2 by the protein kinase inhibitor staurosporine are dependent on the retinoblastoma protein in the bladder carcinoma cell line 5637
Joachim B. Schnier, Kayoko Nishi, David W. Goodrich, and E. Morton Bradbury
Membrane healing and restoration of contractility 5996-6001 after mechanical injury in isolated skeletal muscle fibers of the frog
H. Gonzalez-Serratos, M. Rozycka, R. Cordoba-Rodriguez, and A. Ortega
Evidence from disruption of the lmcpb gene array of 6008-6013 Leishmania mexicana that cysteine proteinases are virulence factors
Jeremy C. Mottram, Augustine E. Souza, J. Elizabeth Hutchison, Roderick Carter, Mhairi J. Frame, and Graham H. Coombs
Cell cycle-dependent modulation of telomerase 6091-6095 activity in tumor cells
Xueli Zhu, Rakesh Kumar, Mahitosh Mandal, Neeta Sharma, Harsh W. Sharma, Urvashi Dhingra, John A. Sokoloski, Rongshen Hsiao, and Ramaswamy Narayanan
DEVELOPMENTAL BIOLOGY
Independent determination of symmetry and polarity 5737-5741 in the Drosophila eye
Kwang-Wook Choi, Brian Mozer, and Seymour Benzer
The embryonic transcription factor stage specific 5802-5807 activator protein contains a potent bipartite activation domain that interacts with several RNA polymerase II basal transcription factors
Jeffery DeFalco and Geoffrey Childs
Scatter factor/hepatocyte growth factor as a regulator 5866-5871 of skeletal muscle and neural crest development
Hisashi Takayama, William J. LaRochelle, Miriam Anver, Dale E. Bockman, and Glenn Merlino
Mutations in the rotated abdomen locus affect muscle 6048-6052 development and reveal an intrinsic asymmetry in Drosophila
Enrique Martin-Blanco and Antonio Garcfa-Bellido
Cell-type and promoter-context dependent retinoic 6197-6202 acid receptor (RAR) redundancies for RAR,B2 and Hoxa-1 activation in F9 and P19 cells can be artefactually generated by gene knockouts
Reshma Taneja, Bidyut Roy, Jean-Luc Plassat, Chris F. Zusi, Jacek Ostrowski, Peter R. Reczek, and Pierre Chambon
ECOLOGY
Maternal effort mediates the prevalence of 5726-5730 trypanosomes in the offspring of a passerine bird
Santiago Merino, Jaime Potti, and Juan Moreno
EVOLUTION
Similarities and dissimilarities of phage genomes 5854-5859 B. Edwin Blaisdell, Allan M. Campbell, and Samuel Karlin
Earliest evolution associated with closure of the 6069-6072 Tropical American Seaway
Laurel S. Collins, Ann F. Budd, and Anthony G. Coates
GENETICS
Segregation of DNA polynucleotide strands into sister 5765-5769 chromatids and the use of endoreduplicated cells to track sister chromatid exchanges induced by crosslinks, alkylations, or x-ray damage
Sheldon Wolff and Veena Afzal
A single gene mutation that increases maize 5824-5829 seed weight
Michael J. Giroux, Janine Shaw, Gerard Barry, B. Greg Cobb, Thomas Greene, Thomas Okita, and L. Curtis Hannah
A JAK-STAT pathway regulates wing vein 5842-5847 formation in Drosophila
Riqiang Yan, Hong Luo, James E. Darnell, Jr., and Charles R. Dearolf
Two genes abrogate the inhibition of murine 5848-5853 hepatocarcinogenesis by ovarian hormones
Therese M. Poole and Norman R. Drinkwater
Efficient in vivo manipulation of mouse genomic 5860-5865 sequences at the zygote stage
Merja Lakso, Jose G. Pichel, James R. Gorman, Brian Sauer, Yo Okamoto, Eric Lee, Frederick W. Alt, and Heiner Westphal
v
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Complementation of the beige mutation in cultured 5905-5909 cells by episomally replicating murine yeast artificial chromosomes
Charles M. Perou, Monica J. Justice, Robert J. Pryor, and Jerry Kaplan
RIG-E, a human homolog of the murine Ly-6 family, 5910-5914 is induced by retinoic acid during the differentiation of acute promyelocytic leukemia cell
Mao Mao, Man Yu, Jian-Hua Tong, Jing Ye, Jun Zhu, Qiu-Hua Huang, Gang Fu, Long Yu, Shou-Yuan Zhao, Samuel Waxman, Michel Lanotte, Zhen-Yi Wang, Jia-Zhen Tan (C. C. Tan), Sai-Juan Chan, and Zhu Chen
Presynaptic association of Rad5l protein with selected 5920-5924 sites in meiotic chromatin
Annemieke W. Plug, Jihong Xu, Gurucharan Reddy, Efim I. Golub, and Terry Ashley
An Escherichia coli chromosomal "addiction module" 6059-6063 regulated by 3',5'-bispyrophosphate: A model for programmed bacterial cell death
Einat Aizenman, Hanna Engelberg-Kulka, and Gad Glaser
Novel human DNA alkyltransferases obtained by 6124-6128 random substitution and genetic selection in bacteria
Fred C. Christians and Lawrence A. Loeb
Age-specific inbreeding depression and components of 6140-6145 genetic variance in relation to the evolution of senescence
Brian Charlesworth and Kimberly A. Hughes
Generation of mice with a 200-kb amyloid precursor 6158-6162 protein gene deletion by Cre recombinase-mediated site-specific recombination in embryonic stem cells
Zhi-Wei Li, Gerlinde Stark, Jurgen Gotz, Thomas Rulicke, Ulrike Muller, and Charles Weissmann
Centromere mapping and orientation of the molecular 6163-6168 linkage map of rice (Oryza sativa L.)
Kuldeep Singh, Takashige Ishii, Arnold Parco, Ning Huang, Darshan S. Brar, and Gurdev S. Khush
Pantropic retroviral vectors integrate and express in 6181-6185 cells of the malaria mosquito, Anopheles gambiae
Tomoyo Matsubara, Richard W. Beeman, Hiroko Shike, Nora J. Besansky, Odette Mukabayire, Stephen Higgs, Anthony A. James, and Jane C. Burns
Flp recombinase promotes site-specific DNA 6191-6196 recombination in embryonic stem cells and transgenic mice
Susan M. Dymecki
IMMUNOLOGY
The nu gene acts cell-autonomously and is required 5742-5746 for differentiation of thymic epithelial progenitors
C. C. Blackburn, C. L. Augustine, R. Li, R. P. Harvey, M. A. Malin, R. L. Boyd, J. F. A. P. Miller, and G. Morahan
Granzyme A is critical for recovery of mice from 5783-5787 infection with the natural cytopathic viral pathogen, ectromelia
Arno Mullbacher, Klaus Ebnet, Robert V. Blanden, Ron Tha Hla, Thomas Stehle, Crisan Museteanu, and Markus M. Simon
Serological analysis of Melan-A(MART-1), a 5915-5919 melanocyte-specific protein homogeneously expressed in human melanomas
Yao-Tseng Chen, Elisabeth Stockert, Achim Jungbluth, Solam Tsang, Keren A. Coplan, Matthew J. Scanlan, and Lloyd J. Old
Novel unconventional binding site in the variable 6019-6024 region of immunoglobulins
Krishnan Rajagopalan, Gabriela Pavlinkova, Shoshana Levy, Phani Raj Pokkuluri, Marianne Schiffer, Boyd E. Haley, and Heinz Kohler
The association between glycosylphosphatidylinositol- 6053-6058 anchored proteins and heterotrimeric G protein a subunits in lymphocytes
Keith R. Solomon, Christopher E. Rudd, and Robert W. Finberg
Isolation of an immunodominant viral peptide that is 6135-6139 endogenously bound to the stress protein GP96/GRP94
Thomas J. F. Nieland, M. C. Agnes A. Tan, Monique Monnee-van Muijen, Frits Koning, Ada M. Kruisbeek, and Grada M. van Bleek
MEDICAL SCIENCES
Second generation hybrid polar compounds are potent 5705-5708 inducers of transformed cell differentiation
V. M. Richon, Y. Webb, R. Merger, T. Sheppard, B. Jursic, L. Ngo, F. Civoli, R. Breslow, R. A. Rifkind, and P. A. Marks
A new adenoviral vector: Replacement of all viral 5731-5736 coding sequences with 28 kb of DNA independently expressing both full-length dystrophin and 3-galactosidase
Stefan Kochanek, Paula R.Clemens, Kohnosuke Mitani, Hsiao-Huei Chen, Suzanne Chan, and C. Thomas Caskey
Stimulation of new bone formation by direct transfer 5753-5758 of osteogenic plasmid genes
Jianming Fang, Yao-Yao Zhu, Elizabeth Smiley, Jeffrey Bonadio, Jeffrey P. Rouleau, Steven A. Goldstein, Laurie K. McCauley, Beverly L. Davidson, and Blake J. Roessler
The recombinant proregion of transforming growth 5877-5882 factor 1 (Latency-associated peptide) inhibits active transforming growth factor ,B1 in transgenic mice
Erwin P. Bottinger, Valentina M. Factor, Monica L.-S. Tsang, James A. Weatherbee, Jeffrey B. Kopp, Su Wen Qian, Lalage M. Wakefield, Anita B. Roberts, Snorri S. Thorgeirsson, and Michael B. Sporn
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Contents Intercellular transfer of a glycosylphosphatidylinositol 5894-5898 (GPI)-linked protein: Release and uptake of CD4-GPI from recombinant adeno-associated virus-transduced HeLa cells
Stacie M. Anderson, Gang Yu, Mara Giattina, and Jeffery L. Miller
Urokinase-type plasminogen activator is effective in 5899-5904 fibrin clearance in the absence of its receptor or tissue-type plasminogen activator
Thomas H. Bugge, Matthew J. Flick, Mary Jo S. Danton, Cynthia C. Daugherty, John R0mer, Keld Dan0, Peter Carmeliet, Desire Collen, and Jay L. Degen
PR-39, a proline-rich antibacterial peptide that 6014-6018 inhibits phagocyte NADPH oxidase activity by binding to Src homology 3 domains of p47phox
Jishu Shi, Christopher R. Ross, Thomas L. Leto, and Frank Blecha
Human immunodeficiency virus tat gene transfer to 6073-6078 the murine central nervous system using a replication-defective herpes simplex virus vector stimulates transforming growth factor beta 1 gene expression
Siyamak Rasty, Prakash Thatikunta, Jennifer Gordon, Kamel Khalili, Shohreh Amini, and Joseph C. Glorioso
The molecular basis of Sanfilippo syndrome type B 6101-6105 Hong G. Zhao, Hong Hua Li, Gideon Bach, Artur Schmidtchen, and Elizabeth F. Neufeld
Recombination leads to the rapid emergence of 6106-6111 HIV-1 dually resistant mutants under selective drug pressure
Laure Moutouh, Jacques Corbeil, and Douglas D. Richman
Deregulation of PAX-5 by translocation of the Eb 6129-6134 enhancer of the IgH locus adjacent to two alternative PAX-5 promoters in a diffuse large-cell lymphoma
Meinrad Busslinger, Norman Klix, Peter Pfeffer, Paula G. Graninger, and Zbynek Kozmik
Modulation of AP-1 activity by the human 6169-6174 progesterone receptor in endometrial adenocarcinoma cells
Ana-Maria Bamberger, Christoph M. Bamberger, Birgit Gellersen, and Heinrich M. Schulte
Genomic cloning of methylthioadenosine 6203-6208 phosphorylase: A purine metabolic enzyme deficient in multiple different cancers
Tsutomu Nobori, Kenji Takabayashi, Phuoc Tran, Lisa Orvis, Ayse Batova, Alice L. Yu, and Dennis A. Carson
MICROBIOLOGY
priA suppressors in Escherichia coli relieve the proton 5953-5957 electrochemical gradient dependency of translocation of wild-type precursors
Nico Nouwen, Ben de Kruijff, and Jan Tommassen
Perpetuation of the agent of human granulocytic 6209-6214 ehrlichiosis in a deer tick-rodent cycle
Sam R. Telford III, Jacqueline E. Dawson, Paula Katavolos, Cynthia K. Warner, Christopher P. Kolbert, and David H. Persing
NEUROBIOLOGY
Receptor stimulation causes slow inhibition of IRK1 5819-5823 inwardly rectifying K+ channels by direct protein kinase A-mediated phosphorylation
Erhard Wischmeyer and Andreas Karschin
Promotion of sleep mediated by the A2a-adenosine 5980-5984 receptor and possible involvement of this receptor in the sleep induced by prostaglandin D2 in rats
Shinsuke Satoh, Hitoshi Matsumura, Fumio Suzuki, and Osamu Hayaishi
Substrate-bound agrin induces expression of 5985-5990 acetylcholine receptor ?-subunit gene in cultured mammalian muscle cells
Graham Jones, Alexander Herczeg, Markus A. Ruegg, Marianne Lichtsteiner, Stephan Kroger, and Hans Rudolf Brenner
The glycine binding site of the N-methyl-D-aspartate 6031-6036 receptor subunit NR1: Identification of novel determinants of co-agonist potentiation in the extracellular M3-M4 loop region
Hirokazu Hirai, Joachim Kirsch, Bodo Laube, Heinrich Betz, and Jochen Kuhse
Magnetic resonance imaging (MRI) detection of the 6037-6042 murine brain response to light: Temporal differentiation and negative functional MRI changes
Wei Huang, Ildik6 Palyka, HaiFang Li, Edward M. Eisenstein, Nora D. Volkow, and Charles S. Springer, Jr.
An axoplasmic myosin with a calmodulin-like 6064-6068 light chain
Elaine L. Bearer, Joseph A. DeGiorgis, Howard Jaffe, Nelson A. Medeiros, and Thomas S. Reese
Behavioral genetics of thermosensation and 6079-6084 hygrosensation in Drosophila
Omer Sayeed and Seymour Benzer
Expression of corticotropin-releasing factor in 6096-6100 inflamed tissue is required for intrinsic peripheral opioid analgesia
Michael Schafer, Shaaban A. Mousa, Qin Zhang, Laurenda Carter, and Christoph Stein
Inhibition of sustained gamma oscillations (35-80 Hz) 6112-6117 by fast transient responses in cat visual cortex
Wolfgang Kruse and Reinhard Eckhorn
A single residue in the M2-M3 loop is a major 6118-6123 determinant of coupling between binding and gating in neuronal nicotinic receptors
Antonio Campos-Caro, Salvador Sala, Juan Jose Ballesta, Francisco Vicente-Agullo, Manuel Criado, and Francisco Sala
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Mutation of a conserved serine in TM4 of opioid 5715-5719 receptors confers full agonistic properties to classical antagonists
Patricia A. Claude, Diane R. Wotta, X. H. Zhang, Paul L. Prather, Terry M. McGinn, Laurie J. Erickson, Horace H. Loh, and P. Y. Law
PHYSIOLOGY
The heart communicates with the kidney exclusively 6215-6219 through the guanylyl cyclase-A receptor: Acute handling of sodium and water in response to volume expansion
Ichiro Kishimoto, Susan K. Dubois, and David L. Garbers
PLANT BIOLOGY
A new hemoglobin gene from soybean: A role for 5682-5687 hemoglobin in all plants
Carol R. Andersson, Erik Ostergaard Jensen, Danny J. Llewellyn, Elizabeth S. Dennis, and W. James Peacock
Enhanced green fluorescence by the expression of an 5888-5893 Aequorea victoria green fluorescent protein mutant in mono- and dicotyledonous plant cells
Christoph Reichel, Jaideep Mathur, Peter Eckes, Kerstin Langenkemper, Csaba Koncz, Jeff Schell, Bernd Reiss, and Christoph Maas
POPULATION BIOLOGY
Behavior predicts genetic structure in a wild 5797-5801 primate group
Jeanne Altmann, Susan C. Alberts, Susan A. Haines, Jean Dubach, Philip Muruthi, Trevor Coote, Eli Geffen, David J. Cheesman, Raphael S. Mututua, Serah N. Saiyalel, Robert K. Wayne, Robert C. Lacy, and Michael W. Bruford
Social Sciences
ECONOMIC SCIENCES
An endogenous rate of time preference, the Penrose 5770-5776 effect, and dynamic optimality of environmental quality
Hirofumi Uzawa
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