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Front MatterSource: Proceedings of the National Academy of Sciences of the United States of America,Vol. 95, No. 24 (Nov. 24, 1998), pp. i-viiiPublished by: National Academy of SciencesStable URL: http://www.jstor.org/stable/46474 .
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PROCEEDINGS
OF THE
NATIONAL ACADEMY OF SCIENCES
OF THE UNITED STATES OF AMEJRICA
November 24, 1998
Volume 95/ Number 24
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PROCEEDINGS
OF THE
NATIO)NAL ACADEMY OF S CIENCES
OF THE UNITED STATES OF AMERICA
November 24, 1998 Volume 95, Number 24 pp. 13999-14586
Table of Contents
Commentaries
The rise of single-molecule DNA biochemistry 13999-14000 Alexander Rich * See companion article on page 14152
T cell receptor antagonism in vivo, at last 14001-14002 Stephen C. Jameson * See companion article on page 14332
Mass migration of a group I intron: Promiscuity 14003-14005 on a grand scale
Michael W. Gray * See companion article on page 14244
Interactions of Salmonella with host cells: Encounters 14006-14008 of the closest kind
Jorge E. Galan * See companion article on page 14057
Inaugural Article Paleoindian large mammal hunters on the plains of 14576-14583 North America
George C. Frison
Physical Sciences
APPLIED PHYSICAL SCIENCES
Hypsographic demography: The distribution of 14009-14014 human population by altitude
Joel E. Cohen and Christopher Small
Ultrasonic tagging of light: Theory 14015-14019 G. D. Mahan, W. E. Engler, J. J. Tiemann, and E. Uzgiris
CHEMISTRY
Inhibition of dipeptidyl peptidase IV by 14020-14024 fluoroolefin-containing N-peptidyl-O-hydroxylamine peptidomimetics
Jian Lin, Paul J. Toscano, and John T. Welch
MATHEMATICS
Regular and stochastic dynamics in the real 14025-14027 quadratic family
Mikhail Lyubich
Biological Sciences
AGRICULTURAL SCIENCES
Transgenic cattle produced by reverse-transcribed 14028-14033 gene transfer in oocytes
Anthony W. S. Chan, E. Jane Homan, Linda U. Ballou, Jane C. Burns, and Robert D. Bremel
The pir gene of Erwinia chrysanthemi EC16 regulates 14034-14039 hyperinduction of pectate lyase virulence genes in response to plant signals
Kinya Nomura, William Nasser, Hirokazu Kawagishi, and Shinji Tsuyumu
iii
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Contents
Insecticide resistance resulting from an absence of 14040-14044 target-site gene product
Thomas G. Wilson and Mudgapalli Ashok
BIOCHEMISTRY
Structural basis for efficient phosphorylation of 14045-14050 3'-azidothymidine monophosphate by Escherichia coli thymidylate kinase
Arnon Lavie, Nils Ostermann, Ralf Brundiers, Roger S. Goody, Jochen Reinstein, Manfred Konrad, and Ilme Schlichting
In vitro selection of RNA molecules that displace 14051-14056 cocaine from the membrane-bound nicotinic acetylcholine receptor
Henning Ulrich, Joseph E. Ippolito, On6 R. Pagain, Vesna A. Eterovic, Richard M. Hann, Hua Shi, John T. Lis, Mohyee E. Eldefrawi, and George P. Hess
SopB, a protein required for virulence of Salmonella 14057-14059 dublin, is an inositol phosphate phosphatase
F. Anderson Norris, Monita P. Wilson, Timothy S. Wallis, Edouard E. Galyov, and Philip W. Majerus * See Commentary on page 14006
A transmembrane form of annexin XII detected by 14060-14065 site-directed spin labeling
Rali Langen, J. Mario Isas, Wayne L. Hubbell, and Harry T. Haigler
DNA end-joining catalyzed by human 14066-14070 cell-free extracts
Peter Baumann and Stephen C. West
Overexpression of peptide-methionine sulfoxide 14071-14075 reductase in Saccharomyces cerevisiae and human T cells provides them with high resistance to oxidative stress
Jackob Moskovitz, Eliezer Flescher, Barbara S. Berlett, Janeen Azare, J. Michael Poston, and Earl R. Stadtman
The orientation of the AP-1 heterodimer on DNA 14076-14081 strongly affects transcriptional potency
Milan Chytil, Blake R. Peterson, Daniel A. Erlanson, and Gregory L. Verdine
032-Adrenergic receptor regulation by GITI, a G 14082-14087 protein-coupled receptor kinase-associated ADP ribosylation factor GTPase-activating protein
Richard T. Premont, Audrey Claing, Nicolas Vitale, Jennifer L. R. Freeman, Julie A. Pitcher, Walter A. Patton, Joel Moss, Martha Vaughan, and Robert J. Lefkowitz
A pyrimidine-rich exonic splicing suppressor binds 14088-14093 multiple RNA splicing factors and inhibits spliceosome assembly
Zhi-Ming Zheng, Martijn Huynen, and Carl C. Baker
Protein tyrosine phosphatase PTP1B suppresses p210 14094-14099 bcr-abl-induced transformation of Rat-i fibroblasts and promotes differentiation of K562 cells
Kenneth R. LaMontagne, Jr., Greg Hannon, and Nicholas K. Tonks
Nitrosative stress: Metabolic pathway involving 14100-14105 the flavohemoglobin
Alfred Hausladen, Andrew J. Gow, and Jonathan S. Stamler
The f subunit sliding DNA clamp is responsible for 14106-14111 unassisted mutagenic translesion replication by DNA polymerase III holoenzyme
Guy Tomer, Nina Bacher Reuven, and Zvi Livneh
Multiple domains of repressor activator protein 1 14112-14117 contribute to facilitated binding of glycolysis regulatory protein 1
M. Cecilia L6pez, Jeffery B. Smerage, and Henry V. Baker
Host factor I, Hfq, binds to Escherichia coli ompA 14118-14123 mRNA in a growth rate-dependent fashion and regulates its stability
Oresta Vytvytska, Jimmy S. Jakobsen, Gina Balcunaite, Jens S. Andersen, Manuela Baccarini, and Alexander von Gabain
Filament structure as an essential factor for 14124-14129 regulation of Dictyostelium myosin by regulatory light chain phosphorylation
Xiong Liu, Kohji Ito, Sayuri Morimoto, Atsuko Hikkoshi-Iwane, Toshio Yanagida, and Taro 0. P. Uyeda
Ribosome display efficiently selects and evolves 14130-14135 high-affinity antibodies in vitro from immune libraries
Jozef Hanes, Lutz Jermutus, Susanne Weber-Bornhauser, Hans Rudolf Bosshard, and Andreas Pluickthun
A functional homolog of a yeast tRNA splicing 14136-14141 enzyme is conserved in higher eukaryotes and in Escherichia coli
Sherry L. Spinelli, Harmit S. Malik, Sandra A. Consaul, and Eric M. Phizicky
BIOPHYSICS
A transient expansion of the native state precedes 14142-14146 aggregation of recombinant human interferon-y
Brent S. Kendrick, John F. Carpenter, Jeffrey L. Cleland, and Theodore W. Randolph
NMR scalar couplings across Watson-Crick base pair 14147-14151 hydrogen bonds in DNA observed by transverse relaxation-optimized spectroscopy
Konstantin Pervushin, Akira Ono, C6sar Fernandez, Thomas Szyperski, Masatsune Kainosho, and Kurt Wuithrich
Stretched and overwound DNA forms a Pauling-like 14152-14157 structure with exposed bases
J. F. Allemand, D. Bensimon, R. Lavery, and V. Croquette * See Commentary on page 13999
iv
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Contents
CELL BIOLOGY
A widely expressed (3111 spectrin associated with 14158-14163 Golgi and cytoplasmic vesicles
Michael C. Stankewich, Williarri T. Tse, Luanne L. Peters, Yeang Ch'ng, Kathryn M. John, Paul R. Stabach, Prasad Devarajan, Jon S. Morrow, and Samuel E. Lux
Quantitative insight into proliferation and 14164-14167 differentiation of oligodendrocyte type 2 astrocyte progenitor cells in vitro
Andrej Y. Yakovlev, Kenneth Boucher, Margot Mayer-Proschel, and Mark Noble
Insulin depletion leads to adipose-specific cell death 14168-14172 in obese but not lean mice
Thomas M. Loftus, Francis P. Kuhajda, and M. Daniel Lane
Nucleosomes, linker DNA, and linker histone form a 14173-14178 unique structural motif that directs the higher-order folding and compaction of chromatin
Jan Bednar, Rachel A. Horowitz, Sergei A. Grigoryev, Lenny M. Carruthers, Jeffrey C. Hansen, Abraham J. Koster, and Christopher L. Woodcock
An essential role of phosphatidylinositol 3-kinase in 14179-14183 myogenic differentiation
Bing-Hua Jiang, Jenny Z. Zheng, and Peter K. Vogt
Unmasking the functions of the chromaffin cell a7 14184-14189 nicotinic receptor by using short pulses of acetylcholine and selective blockers
Manuela G. L6pez, Carmen Montiel, Carlos J. Herrero, Esther Garcia-Palomero, Ines Mayorgas, Jesus M. Hernandez-Guijo, M. Villarroya, Roman Olivares, Luis Gandia, J. Michael McIntosh, Baldomero M. Olivera, and Antonio G. Garcia
A theory for controlling cell cycle dynamics using a 14190-14195 reversibly binding inhibitor
Timothy S. Gardner, Milos Dolnik, and James J. Collins
Tumor necrosis factor-ae induces adhesion molecule 14196-14201 expression through the sphingosine kinase pathway
Pu Xia, Jennifer R. Gamble, Kerry-Anne Rye, Lijun Wang, Charles S. T. Hii, Peter Cockerill, Yeesim Khew-Goodall, Andrew G. Bert, Philip J. Barter, and Mathew A. Vadas
Inhibition of tumorigenicity of the teratoma PC cell 14202-14207 line by transfection with antisense cDNA for PC cell-derived growth factor (PCDGF, epithelin/granulin precursor)
Haidi Zhang and Ginette Serrero
DEVELOPMENTAL BIOLOGY
Testatin: A cystatin-related gene expressed during 14208-14213 early testis development
Virpi Tohonen, Christina Osterlund, and Katarina Nordqvist
Endothelin 3 selectively promotes survival and 14214-14219 proliferation of neural crest-derived glial and melanocytic precursors in vitro
Ronit Lahav, Elisabeth Dupin, Laure Lecoin, Corinne Glavieux, Delphine Champeval, Catherine Ziller, and Nicole M. Le Douarin
Expression of myogenin during embryogenesis is 14220-14225 controlled by Six/sine oculis homeoproteins through a conserved MEF3 binding site
Francois Spitz, Josiane Demignon, Arlette Porteu, Axel Kahn, Jean-Paul Concordet, Dominique Daegelen, and Pascal Maire
EVOLUTION
Complete mitochondrial genome suggests diapsid 14226-14231 affinities of turtles
Rafael Zardoya and Axel Meyer
Genetic control of social organization in an ant 14232-14237 Kenneth G. Ross and Laurent Keller
Persistence of neutral polymorphisms in Lake 14238-14243 Victoria cichlid fish
Sandra Nagl, Herbert Tichy, Werner E. Mayer, Naoyuki Takahata, and Jan Klein
Explosive invasion of plant mitochondria by a group 14244-14249 I intron
Yangrae Cho, Yin-Long Qiu, Peter Kuhlman, and Jeffrey D. Palmer M See Commentary on page 14003
A heterodimeric DNA polymerase: Evidence that 14250-14255 members of Euryarchaeota possess a distinct DNA polymerase
Isaac K. 0. Cann, Kayoko Komori, Hiroyuki Toh, Satoru Kanai, and Yoshizumi Ishino
Stomatal plugs of Drimys winteri (Winteraceae) 14256-14259 protect leaves from mist but not drought
Taylor S. Feild, Maciej A. Zwieniecki, Michael J. Donoghue, and N. Michele Holbrook
Complexities in the genetic structure of Anopheles 14260-14265 gambiae populations in west Africa as revealed by microsatellite DNA analysis
Gregory C. Lanzaro, Yeya T. Toure, John Carnahan, Liangbiao Zheng, Guimogo Dolo, Sekou Traore, Vincenzo Petrarca, Kenneth D. Vernick, and Charles E. Taylor
Somatic hypermutation of the new antigen receptor 14343-14348 gene (NAR) in the nurse shark does not generate the repertoire: Possible role in antigen-driven reactions in the absence of germinal centers
Marilyn Diaz, Andrew S. Greenberg, and Martin F. Flajnik
GENETICS
Targeting cyclin-dependent kinases in Drosophila 14266-14271 with peptide aptamers
Mikhail G. Kolonin and Russell L. Finley, Jr.
An artificial cell-cycle inhibitor isolated from a 14272-14277 combinatorial library
Barak A. Cohen, Pierre Colas, and Roger Brent
v
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Contents
Physical interaction between components of DNA 14278-14283 mismatch repair and nucleotide excision repair
Pascale Bertrand, Daniel X. Tishkoff, Nicole Filosi, Ruchira Dasgupta, and Richard D. Kolodner
The role of alternative mRNA splicing in generating 14284-14289 heterogeneity within the Anopheles gambiae class I glutathione S-transferase family
Hilary Ranson, Frank Collins, and Janet Hemingway
Tsetse thrombin inhibitor: Bloodmeal-induced 14290-14295 expression of an anticoagulant in salivary glands and gut tissue of Glossina niorsitans miorsitans
Michael Cappello, Song Li, Xiaoai Chen, Chang-Ben Li, Lisa Harrison, Sukanya Narashimhan, Charles B. Beard, and Serap Aksoy
Chromosomal arm replacement generates a high level 14296-14301 of intraspecific polymorphism in the terminal inverted repeats of the linear chromosomal DNA of StUeptolyces ambofaciens
Gilles Fischer, Thomas Wenner, Bernard Decaris, and Pierre Leblond
Autoregulation at the level of mRNA 3' end 14302-14307 for-mation of the suppressor of forked gene of Dr-osophila mielanogaster is conserved in Drosophila vi/ilis
Agnes Audibert and Martine Simonelig
IMMUNOLOGY
Activation of human monocytes induces differential 14308-14313 resistance to apoptosis with rapid down regulation of caspase-8/FLICE
Liyanage P. Perera and Thomas A. Waldmann
Presentation of peptide antigens by mouse CD1 14314-14319 requires ondosomal localization and protein antigen processing
Shabnam Tangri, Laurent Brossay, Nicolas Burdin, Delphine J. Lee, Maripat Corr, and Mitchell Kronenberg
Altered peptide ligands act as partial agonists by 14320-14325 inhibiting phospholipase C activity induced by myasthenogenic T cell epitopes
Anat Faber-Elmann, Miri Paas-Rozner, Michael Sela, and Edna Mozes
Differential binding to HLA-C of p50-activating and 14326-1-4331 p58-inhibitory natural killer cell receptors
Mar Va1es-G6mez, Hugh T. Reyburn, Robert A. Erskine, and Jack Strominger
In vivo antagonism of a T cell response by an 14332-14336 endogenously expressed ligand
Devraj Basu, Calvin B. Williams, and Paul M. Allen * See Commentaiy on page 1400!
Analysis of the Drosophila host defense in domino 14337-14342 mutant larvae, which are devoid of hemocytes
Anne Braun, Jules A. Hoffmann, and Marie Meister
Somatic hypermutation of the new antigen receptor 14343-14348 gene (NAR) in the nurse shark does not generate the repertoire: Possible role in antigen-driven reactions in the absence of germinal centers
Marilyn Diaz, Andrew S. Greenberg, and Martin F. Flajnik
Inhibition of intrathymic T cell development by 14349-14354 expression of a transgenic antagonist peptide
Christiaan N. Levelt, Emiko Mizoguchi, Xin Huang, Rebecca Zacks, Atul K. Bhan, and Susumu Tonegawa
MEDICAL SCIENCES
HIV type-i infection of the cotton rat (Sigmodon 14355-14360
ftilviventer and S. hispidus) Raymond J. Langley, Gregory A. Prince, and Harold S. Ginsberg
Identification of morc (micror-chidia), a mutation that 14361-1.4366 results in arrest of spermatogenesis at an early meiotic stage in the mouse
Mark L. Watson, Andrew R. Zinn, Norimitsu Inoue, Karl D. Hess, John Cobb, Mary Ann Handel, Ruth Halaban, Clark C. Duchene, George M. Albright, and Randall W. Moreadith
Endothelin ETA receptor blockade restores 14367-14372 NO-mediated endothelial function and inhibits atherosclerosis in apolipoprotein E-deficient mice
Matthias Barton, Christian C. Haudenschild, Livius V. d'Uscio, Sidney Shaw, Klaus Munter, and Thomas F. Luscher
Vasoactive intestinal peptide inhibits human small-cell 14373-14378 lung cancer proliferation in vitro and in vivo
Kaname Maruno, Afaf Absood, and Sami I. Said
Uncoupling signal transducers from oncogenic MET 14379-14383 mutants abrogates cell transformation and inhibits invasive growth
Alberto Bardelli, Paola Longati, Daniela Gramaglia, Cristina Basilico, Luca Tamagnone, Silvia Giordano, Dario Ballinari, Paolo Michieli, and Paolo M. Comoglio
Sustained secretion of human alpha-1-antitrypsin from 14384-14388 murine muscle transduced with adeno-associated virus vectors
Sihong Song, Michael Morgan, Tamir Ellis, Amy Poirier, Kye Chesnut, Jianming Wang, Mark Brantly, Nicholas Muzyczka, Barry J. Byrne, Mark Atkinson, and Terence R. Flotte
Vascular endothelial growth factor C induces 14389-14394 anigiogenesis in vivo
Yihai Cao, Philip Linden, Jacob Farnebo, Renhai Cao, Anna Eriksson, Vijay Kumar, Jian-Hua Qi, Lena Claesson-Welsh, and Kari Alitalo
Liver degeneration and lymphoid deficiencies in mice 14395-14399 lacking suppressor of cytokine signaling-I
Robyn Starr, Donald Metcalf, Andrew G. Elefanty, Marta Brysha, Tracy A. Wilison, Nicos A. Nicola, Douglas J. Hilton, and Warren S. Alexander
vi
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Contents
The cancer growth suppressor gene mda-7 selectively 14400-14405 induces apoptosis in human breast cancer cells and inhibits tumor growth in nude mice
Zao-zhong Su, Malavi T. Madireddi, Jiao Jiao Lin, Charles S. H. Young, Shinichi Kitada, John C. Reed, Neil I. Goldstein, and Paul B. Fisher
Functional analyses of troponin T mutations that 14406-14410 cause hypertrophic cardiomyopathy: Insights into disease pathogenesis and troponin function
H. Lee Sweeney, Huisheng S. Feng, Zhaouhui Yang, and Hugh Watkins
Interferon-/3 gene therapy inhibit.s tumor formation 14411-14416 and causes regression of established tumors in immune-deficient mice
Xiao-Qiang Qin, Nianjun Tao, Amie Dergay, Pamela Moy, Stephen Fawell, Alan Davis, James M. Wilson, and James Barsoum
The mutationally activated Met receptor mediates 14417-14422 motility and metastasis
Michael Jeffers, Michele Fiscella, Craig P. Webb, Miriam Anver, Shahriar Koochekpour, and George F. Vande Woude
Endothelial selectins and vascular cell adhesion 14423-14428 molecule-i promote hematopoietic progenitor homing to bone marrow
Paul S. Frenette, Sangeetha Subbarao, Irina B. Mazo, Ulrich H. von Andrian, and Denisa D. Wagner
Fetuin (ca2-HS-glycoprotein) opsonizes cationic 14429-14434 macrophage-deactivating molecules
Haichao Wang, Minghuang Zhang, Marina Bianchi, Barbara Sherry, Andrew Sama, and Kevin J. Tracey
The neutral glycosphingolipid globotriaosylceramide 14435-14440 promotes fusion mediated by a CD4-dependent CXCR4-utilizing HIV type 1 envelope glycoprotein
Anu Puri, Peter Hug, Kristine Jernigan, Joseph Barchi, Hee-Yong Kim, Jillon Hamilton, Joelle Wiels, Gary J. Murray, Roscoe 0. Brady, and Robert Blumenthal
Stochastic processes strongly influence HIV-1 14441-14446 evolution during suboptimal protease-inhibitor therapy
Monique Nijhuis, Charles A. B. Boucher, Pauline Schipper, Thomas Leitner, Rob Schuurman, and Jan Albert
Perturbation of the T cell repert:oire in rheumatoid 14447-14452 arthritis
Ulf G. Wagner, Kerstin Koetz, Cornelia M. Weyand, and J6rg J. Goronzy
The intrinsic radioresistance of glioblastoma-derived 14453-14458 cell lines is associated with a failure of p53 to induce p2lBAX expression
Hui-Kuo G. Shu, Moses M. Kim, Pengchin Chen, Felix Furman, Carol M. Julin, and Mark A. Israel
Altered regulation of platelet-derived growth factor 14459-14463 receptor-a gene-transcription in vitro by spina bifida-associated mutant Paxi proteins
Paul H. L. J. Joosten, Frans A. Hol, Sylvia B. C. van Beersum, Heiko Peters, Ben C. J. Hamel, Gijs B. Afink, Everardus J. J. van Zoelen, and Edwin C. M. Mariman
MICROBIOLOGY
The Vibrio cholerae genome contains two unique 14464-14469 circular chromosomes
Michele Trucksis, Jane Michalski, Ying Kang Deng, and James B. Kaper
Cellular gene expression altered by human 14470-14475 cytomegalovirus: Global monitoring with oligonucleotide arrays
Hua Zhu, Jian-Ping Cong, Gargi Mamtora, Thomas Gingeras, and Thomas Shenk
NEUROBIOLOGY
Serotonin receptor IA knockout: An animal model 14476-14481 of anxiety-related disorder
Sylvie Ramboz, Ronald Oosting, Djamel Ait Amara, Hank F. Kung, Pierre Blier, Monica Mendelsohn, J. John Mann, Dani Brunner, and Ren6 Hen
Prolonged activation of the N-methyl-D-aspartate 14482-14487 receptor-Ca2+ transduction pathway causes spontaneous recurrent epileptiform discharges in hippocampal neurons in culture
Robert J. DeLorenzo, Shubhro Pal, and Sompong Sombati
Inputs to directionally selective simple cells in 14488-14493 macaque striate cortex
Russell L. De Valois and Nicolas P. Cottaris
Selective effects of methylphenidate in attention 14494-14499 deficit hyperactivity disorder: A functional magnetic resonance study
Chandan J. Vaidya, Glenn Austin, Gary Kirkorian Hugh W. Ridlehuber, John E. Desmond, Gary H. Glover, and John D. E. Gabrieli
Chemokines regulate hippocampal neuronal signaling 14500-14505 and gp120 neurotoxicity
Olimpia Meucci, Alessandro Fatatis, Arthur A. Simen, Trevor J. Bushell, Patrick W. Gray, and Richard J. Miller
Hippocampal, but not amygdala, activity at encoding 14506-14510 correlates with long-term, free recall of nonemotional information
Michael T. Alkire, Richard J. Haier, James H. Fallon, and Larry Cahill
Suppression of protein synthesis in brain during 14511-14516 hibernation involves inhibition of protein initiation and elongation
Kai U. Frerichs, Carolyn B. Smith, Michael Brenner, Donald J. DeGracia, Gary S. Krause, Laura Marrone, Thomas E. Dever, and John M. Hallenbeck
Effect of reduced myristoylated alanine-rich C kinase 14517-15422 substrate expression on hippocampal mossy fiber development and spatial learning in mutant mice: Transgenic rescue and interactions with gene background
R. K. McNamara, D. J. Stumpo, L. M. Morel, M. H. Lewis, B. K. Wakeland, P. J. Blackshear, and R. H. Lenox
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Contents
Evidence for a voltage-dependent enhancement of 14523-14528 neurotransmitter release mediated via the synaptic protein interaction site of N-type Ca2+ channels
Sumiko Mochida, Charles T. Yokoyama, D. Kyle Kim, Kanako Itoh, and William A. Catterall
A neuronal model of a global workspace in effortful 14529-14534 cognitive tasks
Stanislas Dehaene, Michel Kerszberg, and Jean-Pierre Changeux
PHARMACOLOGY
Promoting detachment of neutrophils adherent to 14535-14539 murine postcapillary venules to control inflammation: Effect of lipocortin 1
Lina H. K. Lim, Egle Solito, Frangoise Russo-Marie, Roderick J. Flower, and Mauro Perretti
Modes of action of aspirin-like drugs: Salicylates 14540-14545 inhibit Erk activation and integrin-dependent neutrophil adhesion
Michael H. Pillinger, Constance Capodici, Pamela Rosenthal, Neil Kheterpal, Simon Hanft, Mark R. Philips, and Gerald Weissmann
PHYSIOLOGY
Stoichiometry and arrangement of heteromeric 14546-14551 olfactory cyclic nucleotide-gated ion channels
Mark S. Shapiro and William N. Zagotta
The thiazide-sensitive Na-Cl cotransporter is an 14552-14557 aldosterone-induced protein
Gheun-Ho Kim, Shyama Masilamani, Rachel Turner, Carter Mitchell, James B. Wade, and Mark A. Knepper
Rat heart: A site of oxytocin production and action 14558-14563 Marek Jankowski, Fadi Hajjar, Sausan Al Kawas, Suhayla Mukaddam-Daher, Gloria Hoffman, Samuel M. McCann, and Jolanta Gutkowska
Characterization of a murine type II 14564-14569 sodium-phosphate cotransporter expressed in mammalian small intestine
Helene Hilfiker, Olaf Hattenhauer, Martin Traebert, Ian Forster, Heini Murer, and Jiurg Biber
PLANT BIOLOGY
Mode of action of the CORlSa gene on the freezing 14570-14575 tolerance of Arabidopsis thaliana
Peter L. Steponkus, Matsuo Uemura, Raymond A. Joseph, Sarah J. Gilmour, and Michael F. Thomashow
Social Sciences
ANTHROPOLOGY
Paleoindian large mammal hunters on the plains of 14576-14583 North America
George C. Frison
SOCIAL SCIENCES
Hypsographic demography: The distribution of 14009-14014 human population by altitude
Joel E. Cohen and Christopher Small
CORRECTIONS
BIOCHEMISTRY Molecular cloning and characterization of a cellular 14584 phosphoprotein that interacts with a conserved C-terminal domain of adenovirus EIA involved in negative modulation of oncogenic transformation
Ute Schaeper, Janice M. Boyd, Sulekha Verma, Erik Uhlmann, T. Subramanian, and G. Chinnadurai
The TRAP220 component of a thyroid hormone 14584 receptor-associated protein (TRAP) coactivator complex interacts directly with nuclear receptors in a ligand-dependent fashion
Chao-Xing Yuan, Mitsuhiro Ito, Joseph D. Fondell, Zheng-Yuan Fu, and Robert G. Roeder
EVOLUTION The role of robustness and changeability on the origin 14584 and evolution of genetic codes
Tetsuya Maeshiro and Masayuki Kumura
PLANT BIOLOGY Differential expression of two isopentenyl 14585 pyrophosphate isomerases and enhanced carotenoid accumulation in a unicellular chlorophyte
Zairen Sun, Francis X. Cunningham, Jr., and Elisabeth Gantt
AUTHOR INDEX ix-xi
INFORMATION FOR AUTHORS xii-xiv
SIZING WORKSHEET xv
DOCUMENTATION REPORT xvi
COPYRIGHT ASSIGNMENT FORM xvii
SUBSCRIPTION FORM xviii
CLASSIFIED ADVERTISEMENTS xix
Cover photograph: Euclid, the father of geometry: Panel from the bronze doors at the National Academy of Sciences.
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