+ All Categories
Home > Documents > Front Matter

Front Matter

Date post: 02-Jan-2017
Category:
Upload: hoangkiet
View: 212 times
Download: 0 times
Share this document with a friend
11
Front Matter Source: Proceedings of the National Academy of Sciences of the United States of America, Vol. 96, No. 13 (Jun. 22, 1999), pp. i-viii Published by: National Academy of Sciences Stable URL: http://www.jstor.org/stable/48018 . Accessed: 08/05/2014 14:13 Your use of the JSTOR archive indicates your acceptance of the Terms & Conditions of Use, available at . http://www.jstor.org/page/info/about/policies/terms.jsp . JSTOR is a not-for-profit service that helps scholars, researchers, and students discover, use, and build upon a wide range of content in a trusted digital archive. We use information technology and tools to increase productivity and facilitate new forms of scholarship. For more information about JSTOR, please contact [email protected]. . National Academy of Sciences is collaborating with JSTOR to digitize, preserve and extend access to Proceedings of the National Academy of Sciences of the United States of America. http://www.jstor.org This content downloaded from 169.229.32.137 on Thu, 8 May 2014 14:13:23 PM All use subject to JSTOR Terms and Conditions
Transcript

Front MatterSource: Proceedings of the National Academy of Sciences of the United States of America,Vol. 96, No. 13 (Jun. 22, 1999), pp. i-viiiPublished by: National Academy of SciencesStable URL: http://www.jstor.org/stable/48018 .

Accessed: 08/05/2014 14:13

Your use of the JSTOR archive indicates your acceptance of the Terms & Conditions of Use, available at .http://www.jstor.org/page/info/about/policies/terms.jsp

.JSTOR is a not-for-profit service that helps scholars, researchers, and students discover, use, and build upon a wide range ofcontent in a trusted digital archive. We use information technology and tools to increase productivity and facilitate new formsof scholarship. For more information about JSTOR, please contact [email protected].

.

National Academy of Sciences is collaborating with JSTOR to digitize, preserve and extend access toProceedings of the National Academy of Sciences of the United States of America.

http://www.jstor.org

This content downloaded from 169.229.32.137 on Thu, 8 May 2014 14:13:23 PMAll use subject to JSTOR Terms and Conditions

PNAS Proceedings of the National Academy of Sciences of the United States of America

June 22, 1999 vol. 96 no. 13 pp. 7117-7610 www.pnas.org

Structure of the Cre-loxP synapse JC virus and colorectal cancer l

Neanderthals in human evolution

Brain sexual dimorphism and androgens

This content downloaded from 169.229.32.137 on Thu, 8 May 2014 14:13:23 PMAll use subject to JSTOR Terms and Conditions

~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~-q

I~~~~~~~~~~~~~~~~~~~~~~~~.. - 'A! fi

I _E . _ I_

I ~ ~~~~~ I

~~~A _ ill~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~' Ii

_' __~~~~~~~~~~~~~~~~~~~~~~~~~~~

This content downloaded from 169.229.32.137 on Thu, 8 May 2014 14:13:23 PMAll use subject to JSTOR Terms and Conditions

PROCEEDINGS OF THE

NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Officers BRUCE ALBERTS, President of the JACK HALPERN, Vice President Academy PETER H. RAVEN, Home Secretary

F. SHERWOOD ROWLAND, Foreign Secretary RONALD L. GRAHAM, Treasurer

Editor-in-Chief NICHOLAS R. COZZARELLI

PNAS Editorial Board

MAY R. BERENBAUM PETER J. BICKEL MAURICE BURG MARIO R. CAPECCHI WILLIAM CATTERALL ANTHONY CERAMI PIERRE CHAMBON STANLEY N. COHEN DAVID R. DAVIES PETER B. DERVAN HERMAN N. EISEN ANTHONY S. FAUCI NINA FEDOROFF WALTER M. FITCH

JOSEPH L. GOLDSTEIN COREY S. GOODMAN CAROL A. GROSS JACK HALPERN BERTIL HILLE PIERRE C. HOHENBERG Hl. ROBERT HORVITZ TONY HUNTER ERICH P. IPPEN RICHARD V. KADISON ROBERT P. KIRSHNER ALFRED G. KNUDSON ROGER KORNBERG ROBERT LANGER

HARVEY F. LODISH PHIL W. MAJERUS PHILIPPA MARRACK RICHARD D. MCKELVEY HENRY METZGER ARNO G. MOTULSKY JEREMY NATHANS LARRY E. OVERMAN W. JAMES PEACOCK STANLEY B. PRUSINER CHARLES RADDING JEREMY A. SABLOFF PAUL R. SCHIMMEL AARON J. SHATKIN

KAI L. SIMONS CHRISTOPHER A. SIMS SOLOMON H. SNYDER CHRISTOPHER R. SOMERVILLE

$STEVEN M. STANLEY CHARLES F. STEVENS FRANK H. STILLINGER THOMAS P. STOSSEL KARL K. TUREKIAN DAVID WAKE CHRISTOPHER T. WALSH DON C. WILEY PETER G. WOLYNES ROBERT H. WURTZ

Publisher: Executive Editor: Managing Editor: Associate Recruiting Editor: Associate Manager for Production: Editorial Manager/Systems Administrator: Production Coordinator: Editorial Coordinators: Editorial Assistants: Financial Manager: Financial Associate: Financial Assistant:

KENNETH R. FULTON DIANE M. SULLENBERGER JOHN M. MALLOY GuY RIDDIHOUGH JOANNE D'AMIco MARILYN J. MASON BARBARA A. BACON JOAN M. DAWSON, BARBARA J. ORTON, DANIEL H. SALSBURY DORIS DIASE, ELISA GRAY, JOE N. HARPE, RENITA M. JOHNSON JOSEPH F. RZEPKA, JR. JULIA A. LITTLE ANTON BANDY

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (ISSN-0027-8424) is published biweekly by THE NATIONAI ACADEMY OF SCIENCES.

Correspondence: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES, 2101 Constitution Avenue, NW, Washington, DC 20418 USA (via U.S. postal service) or 1055 Thomas Jefferson Street, NW, Suite FO2013, Washington, DC 20007 USA (via courier or express mail). E-mail: PNAS(@nas.edu.

Information for Authors: See pp. xv-xvii (of this issue) or www.pnas.org.

Copyright: Volumes 90-96, copyright ? 1993-1999 by THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, all rights reserved; Volumes 1-89, copyright as a collective work only [author(s) retains copyright to individual articles]. Requests for Permission: Address requests to reproduce material published in Volumes 1-89 to the original author(s); address other requests to the PNAS Permissions Office, 2101 Constitution Avenue, NW, Washington, DC 20418 USA, FAX 1-202-334-2739. Please cite the exact material to be reprinted and state specifically where it will be used. Photocopies: The journal is registered with the Copyright Clearance Center (CCC), 222 Rosewood Drive, Danvers, MA 01923 USA, FAX 1-978-750-4470. Authorization to photocopy items for the internal or personal use of specific clients is granted by THE NATIONAL ACADEMY OF SCIENCES provided that the proper fee is paid directly to CCC. Microforms: Contact University Microfilms Inc., P.O. Box 1346, Ann Arbor, MI 48106-1346 USA. This journal is printed on acid-free paper effective with Volume 84, Issue 1.

Subscriptions: Address subscription correspondence to the PNAS Customer Service/Circulation Office, P.O. Box 5030, Brentwood, TN 37024 USA. Subscriptions are entered on a calendar-year basis only. The 1999 subscription rates for print plus online/online only are as follows-in the U.S.: student/postdoctoral, $110/$20; personal, $165/$100; institutional, $800/n.a.-U.S. by First Class at a surcharge of $160-elsewhere (institutional includes expedited delivery): student/postdoctoral, $235/$20; personal, $290/$100; institutional, $995/n.a.-elsewhere by expedited delivery at a surcharge of $300. Exclusive Agent for Subscribers in Japan: USACO Corporation, 13-12, Shimbashi, 1-Chome, Minato-ku, Tokyo 105 Japan. Change ofAddress: Notify the Customer Service/Circulation Office 6 weeks in advance and list the old and new addresses. PNAS is not responsible for nonreceipt of issues because of an improper address, unless a change of address is on file. Claims: Requests for replacement copies will not be honored more than 60 days after the issue date for domestic subscribers and not more than 90 days after the issue date for foreign subscribers. Claims will not be honored for more than 2 issues per calendar year for the same subscriber. Single Copies: $35 per issue in the U.S., $45 elsewhere. Canadian GST: Registration Number R-133130880.

Advertising: Contact M. J. Mrvica Associates, Inc., 2 West Taunton Avenue, Berlin, NJ 08009 USA. Phone 1-609-768-9360, FAX 1-609-753-0064, E-mail [email protected]. Postmaster: Send address changes to PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES, 2101 Constitution Avenue, NW, Washington, DC 20418 USA. Periodicals postage paid at Washington, DC, and additional mailing offices. PRINTED IN THE USA

PNAS is available online at www.pnas.org.

This content downloaded from 169.229.32.137 on Thu, 8 May 2014 14:13:23 PMAll use subject to JSTOR Terms and Conditions

Reach

EDT's High hogptPG ulheigtr o09A ITalso offers Reverse Phase HPLC, Ion

_ r ; ~~~~~~~~~~~Exchange HPLC or Dual Purification when = needed. Call us!

__ | | ~~~~~~~~~~~~~~Capillary Electrophoresis Results

||Full width: 1 1 minutes to 23 minutes

IDT's High Throughput PAGE ||Full height: O to 0.9 AU

Purification System Provides Mola Purity* PAGE, Pure Custom Oligos IDT Standard 64% PAGEdaystforOnly$30!* 1 | Competitor 28% in 3-5 days for Only $3O!*

Full length of product divided by the sum of all product.

As the leading supplier of highly purified custom

oligonucleotides, IDT has the expertise to help Analysis of the same 40-mer

you select the right purification method for your sequence comparing IDT's

application. Standarddesalting or cartridge-type PAGE purified synthesis to IDT PAGE Purifie purification methods do not provide the level of standard oligos

purity you get with PAGE. If your research Please visit our web

requires oligos that are longer than simple primers, complete report.

IDT's PAGE Pure custom oligos are right for you.

*In addition to the per base cost of the oligo. Available on IDT's purity oligos 10-60 bases in length on our standard 100 nmole scale tandards lead the DNA synthesis.

*0 , R today at: Standard and

easiest~~~~~~~~~ ~~~PGopuf ie

EntetContact IDT's | ois'l'?

id ul,,a y~~~~~~toa at:_ W

--Ata 0t

This content downloaded from 169.229.32.137 on Thu, 8 May 2014 14:13:23 PMAll use subject to JSTOR Terms and Conditions

PROCEEDINGS OF THE

NATIONAL ACADEMY OF SCIENCES

OF THE UNITED STATES OF AMERICA

June 22, 1999 Volume 96, Number 13 pp. 7117-7610

Table of Contents

Commentaries

Hominids and hybrids: The place of Neanderthals in 7117-7119 human evolution

Ian Tattersall and Jeffrey H. Schwartz * See companion article on page 7604

The tangled biology of tau 7120-7121 Kirk C. Wilhelmsen * See companion article on page 5598 in issue 10 of volume 96

Coming or going it's another pretty picture for the 7122-7124 A-Int family album

Arthur Landy * See companion article on page 7143

Augmenting ,B receptors in the heart: Short-term gains 7125-7127 offset by long-term pains?

Lee E. Limbird and Douglas E. Vaughan * See companion article on page 7059 in issue 12 of volume 96

Permanence of brain sex differences and structural 7128-7130 plasticity of the adult brain

Bruce S. McEwen * See companion article on page 7538

Physical Sciences

CHEMISTRY

A method for high-sensitivity peptide sequencing 7131-7136 using postsource decay matrix-assisted laser desorption ionization mass spectrometry

T. Keough, R. S. Youngquist, and M. P. Lacey

Passive entry of a DNA molecule into a small pore 7262-7264 Pierre-Gilles de Gennes

Biological Sciences

BIOCHEMISTRY

Purification of transcription cofactor complex CRSP 7137-7142 Soojin Ryu and Robert Tjian

Asymmetric DNA bending in the Cre-loxP site-specific 7143-7148 recombination synapse

Feng Guo, Deshmukh N. Gopaul, and Gregory D. Van Duyne * See Commentary on page 7122

mRNA cap recognition: Dominant role of enhanced 7149-7154 stacking interactions between methylated bases and protein aromatic side chains

Guanghui Hu, Paul D. Gershon, Alec E. Hodel, and Florante A. Quiocho

iii

This content downloaded from 169.229.32.137 on Thu, 8 May 2014 14:13:23 PMAll use subject to JSTOR Terms and Conditions

Introducing Carl Zeiss Vision 3

Te New Frce In '

Imaging For Microscopy.

Y .~~ ~~~ ~~~ ~~~ ~~~ ~~~ ~~~ ~~~ ~~~ ~~~ ~~~ ~~~ ~~~ ~~~ ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~.........

__~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~

Come to Zeiss for a total solution to your imaging needs. The best microscopes with the best optics, the highest resolu- tion cameras, and now the best imaging software. The new AxioVision

modular image acquisition and archiving system represents a new level of flexibility for digital microscopy. Two modes are available: the application mode for routine, and the expert mode for research. AxioVision is suitable for all biological and

materials applications. The system provides fully integrated control of the microscope and camera; efficient image enhancement; archiving of image, text, measuring data and all microscope parameters; and automatic report generation. We also have specific

programs for 3D deconvolution, confocal microscopy, materials analysis, and the KS Elispot for the automatic evaluation of T-lymphocyte immunoassays.

The Carl Zeiss Vision series covers the full range of count- ing, sizing, statistical evaluation, and image enhancement tools for all research and industrial applications.

For a free evaluation of your imaging needs, contact your Zeiss representative.

Call 800.233.2343 today.

Carl Zeiss Vision total solutions

.for imaging

...........i s c ............... ..2 ...3. ... c....... &............e m s.......4 . ..A....

OneZeissOrive~~~~~~~~~~~~~~~~~ N....... ....... ............ .Y 1 0 5 94...........n

This content downloaded from 169.229.32.137 on Thu, 8 May 2014 14:13:23 PMAll use subject to JSTOR Terms and Conditions

Contents

Chromatin structure analysis of the mouse Xist locus 7155-7160 Veronica McCabe, Emma J. Formstone, Laura P. O'Neill, Bryan M. Turner, and Neil Brockdorff

Glutamine synthetase inactivation by 7161-7166 protein-protein interaction

Mario Garcfa-Domfnguez, Jos6 C. Reyes, and Francisco J. Florencio

Substrate-induced closure of the flap domain in the 7167-7171 ternary complex structures provides insights into the mechanism of catalysis by 3-hydroxy 3-methylglutaryl-CoA reductase

Lydia Tabernero, Daniel A. Bochar, Victor W. Rodwell, and Cynthia V. Stauffacher

Identification of SH2-Bf3 as a potent cytoplasmic 7172-7177 activator of the tyrosine kinase Janus kinase 2

Liangyou Rui and Christin Carter-Su

Comparison of the intracellular signaling responses by 7178-7183 three chimeric fibroblast growth factor receptors in PC12 cells

Simona Raffioni, Didier Thomas, Erik D. Foehr, Leslie M. Thompson, and Ralph A. Bradshaw

Heat-inactivated proteins are rescued by the 7184-7189 DnaK-J-GrpE set and ClpB chaperones

Ken Motohashi, Yohei Watanabe, Masafumi Yohda, and Masasuke Yoshida

Bypassing the periplasm: Reconstitution of the AcrAB 7190-7195 multidrug efflux pump of Escherichia coli

Helen I. Zgurskaya and Hiroshi Nikaido

Poisoning of human DNA topoisomerase I by 7196-7201 ecteinascidin 743, an anticancer drug that selectively alkylates DNA in the minor groove

Yuji Takebayashi, Philippe Pourquier, Akira Yoshida, Glenda Kohlhagen, and Yves Pommier

An inactive open complex mediated by an UP 7202-7207 element at Escherichia coli promoters

Hideaki Tagami and Hiroji Aiba

Host-cell positive transcription elongation factor b 7208-7213 kinase activity is essential and limiting for HIV type 1 replication

Osvaldo Flores, Gary Lee, Joseph Kessler, Miclhael Miller, William Schlief, Joanne Tomassini, and Daria Hazuda

NFAT5, a constitutively nuclear NFAT protein that 7214-7219 does not cooperate with Fos and Jun

Cristina L6pez-Rodriguez, Jos6 Aramburu, Andrew S. Rakeman, and Anjana Rao

Identification of human prostaglandin E synthase: A 7220-7225 microsomal, glutathione-dependent, inducible enzyme, constituting a potential novel drug target

Per-Johan Jakobsson, Staffan Thoren, Raif Morgenstern, and Bengt Samuelsson

Purification of the yeast U4/U6 U5 small nuclear 7226-7231 ribonucleoprotein particle and identification of its proteins

Scott W. Stevens and John Abelson

The a-helix folds on the millisecond time scale 7232-7237 David T. Clarke, Andrew J. Doig, Benjamin J. Stapley, and Gareth R. Jones

cDNA cloning of cholesterol 24-hydroxylase, a 7238-7243 mediator of cholesterol homeostasis in the brain

Erik G. Lund, Joseph M. Guileyardo, and David W. Russell

BIOPHYSICS

Electrically driven motor in the outer hair cell: Effect 7244-7249 of a mechanical constraint

M. Adachi and K. H. Iwasa

The active form of the steroidogenic acute regulatory 7250-7255 protein, StAR, appears to be a molten globule

Himangshu S. Bose, Randy M. Whittal, Michael A. Baldwin, and Walter L. Miller

A single amino acid near the C terminus of the 7256-7261 synaptosome-associated protein of 25 kDa (SNAP-25) is essential for exocytosis in chromaffin cells

Manuel Criado, Anabel Gil, Salvador Viniegra, and Luis M. Guti6rrez

Passive entry of a DNA molecule into a small pore 7262-7264 Pierre-Gilles de Gennes

CELL BIOLOGY

Hepatic differentiation induced by oncostatin M 7265-7270 attenuates fetal liver hematopoiesis

Taisei Kinoshita, Takashi Sekiguchi, Ming-jiang Xu, Yoshiaki Ito, Akihide Kamiya, Koh-ichiro Tsuji, Tatsutoshi Nakahata, and Atsushi Miyajima

Receptor recruitment: A mechanism for interactions 7271-7275 between G protein-coupled receptors

Ulla Holtback, lHjalmar Brismar, Gerald F. DiBona, Michael Fu, Paul Greengard, and Anita Aperia

Separation of C/EBPa-mediated proliferation arrest 7276-7281 and differentiation pathways

Christine Muller, Marianna Alunni-Fabbroni, Elisabeth Kowenz-Leutz, Xianming Mo, Massimo Tommasino, and Achim Leutz

A functional bone morphogenetic protein system in 7282-7287 the ovary

Shunichi Shimasaki, Rob J. Zachow, Danmei Li, Holly Kim, Shun-ichiro lemura, Naoto Ueno, Kuber Sampath, R. Jeffrey Chang, and Gregory F. Erickson

Genetic dissection of the budding yeast Arp2/3 7288-7293 complex: A comparison of the in vivo and structural roles of individual subunits

Dirk C. Winter, Elizabeth Y. Choe, and Rong Li

Osteoblast-specific gene expression after 7294-7299 transplantation of marrow cells: Implications for skeletal gene therapy

Zhen Hou, Que Nguyen, Baruch Frenkel, Susan K. Nilsson, Moira Milne, Andre J. van Wijnen, Janet L. Stein, Peter Quesenberry, Jane B. Lian, and Gary S. Stein

v

This content downloaded from 169.229.32.137 on Thu, 8 May 2014 14:13:23 PMAll use subject to JSTOR Terms and Conditions

Contents

Ezrin, a plasma membrane-microfilament linker, 7300-7305 signals cell survival through the phosphatidylinositol 3-kinase/Akt pathway

Alexis Gautreau, Patrick Poullet, Daniel Louvard, and Monique Arpin

Cdc20 associates with the kinase aurora2/Aik 7306-7311 Dawn C. Farruggio, Fiona M. Townsley, and Joan V. Ruderman

The intracellular parasite Theileria par va protects 7312-7317 infected T cells from apoptosis

Volker T. Heussler, Joel Machado, Jr, Paula C. Fernandez, Catherine Botteron, Chao-Guang Chen, Martin J. Pearse, and Dirk A. E. Dobbelaere

DEVELOPMENTAL BIOLOGY

Reprogramming of intestinal differentiation and 7318-7323 intercalary regeneration in Cdx2 mutant mice

Felix Beck, Kallayanee Chawengsaksophak, Paul Waring, Raymond J. Playford, and John B. Furness

Normal growth and development in the absence of 7324-7329 hepatic insulin-like growth factor I

Shoshana Yakar, Jun-Li Liu, Bethel Stannard, Andrew Butler, Domenici Accili, Brian Sauer, and Derek LeRoith

Branching morphogenesis independent of 7330-7335 mesenchymal-epithelial contact in the developing kidney

Jizeng Qiao, Hiroyuki Sakurai, and Sanjay K. Nigam

Selective activation of the versican promoter by 7336-7341 epithelial-mesenchymal interactions during hair follicle development

Jiro Kishimoto, Ritsuko Ehama, Lin Wu, Shuwei Jiang, Nanyan Jiang, and Robert E. Burgeson

ECOLOGY

Folkecology and commons management in the 7598-7603 Maya Lowlands

Scott Atran, Douglas Medin, Norbert Ross, Elizabeth Lynch, John Coley, Edilberto Ucan Ek', and Valentina Vapnarsky

EVOLUTION

MADS-box genes reveal that gnetophytes are more 7342-7347 closely related to conifers than to flowering plants

Kai-Uwe Winter, Annette Becker, Thomas Miinster, Jan T. Kim, Heinz Saedler, and Gunter Theissen

Mutation, recombination, and incipient speciation of 7348-7351 bacteria in the laboratory

Marin Vulic, Richard E. Lenski, and Miroslav Radman

Widespread intra-serotype recombination in natural 7352-7357 populations of dengue virus

Michael Worobey, Andrew Rambaut, and Edward C. Holmes

Proposal for a standardized temporal scheme of 7358-7363 biological classification for extant species

John C. Avise and Glenn C. Johns

GENETICS

Heterogeneous gene expression from the inactive X 7364-7369 chromosome: An X-linked gene that escapes X inactivation in some human cell lines but is inactivated in others

Laura Carrel and Huntington F. Willard

Conditional requirement for the Flk-i receptor in the 7370-7375 in vitro generation of early hematopoietic cells

Michihiro Hidaka, William L. Stinford, and Alan Bernstein

Disruption of mRadSO causes embryonic stem cell 7376-7381 lethality, abnormal embryonic development, and sensitivity to ionizing radiation

Guangbin Luo, Michelle S. Yao, Carla F. Bender, Michael Mills, Anthony R. Bladl, Allan Bradley, and John H. J. Petrini

Rapid p53 sequence analysis in primary lung cancer 7382-7387 using an oligonucleotide probe array

Steven A. Ahrendt, Sarel Halachmi, John T. Chow, Li Wu, Naomi Halachmi, Stephen C. Yang, Scott Wehage, Jin Jen, and David Sidransky

Transglutaminase aggregates huntingtin into 7388-7393 nonamyloidogenic polymers, and its enzymatic activity increases in Huntington's disease brain nuclei

Marcela V. Karpuj, Hideki Garren, Hilda Slunt, Donald L. Price, James Gusella, Mark W. Becher, and Lawrence Steinman

Neurosecretory control of aging in 7394-7397 Caenorhabditis elegans

Michael Ailion, Takao Inoue, Carole I. Weaver, Robert W. Holdcraft, and James H. Thomas

Stimulation of homologous recombination in plants by 7398-7402 expression of the bacterial resolvase RuvC

Gil Shalev, Yaron Sitrit, Naomi Avivi-Ragolski, Conrad Lichtenstein, and Avraham A. ILevy

The natriuretic peptide clearance receptor locally 7403-7408 modulates the physiological effects of the natriuretic peptide system

Naomichi Matsukawa, Wojciech J. Grzesik, Nobuyuki Takahashi, Kailash N. Pandey, Stephen Pang, Mitsuo Yamauchi, and Oliver Smithies

Colinearity and its exceptions in orthologous adh 7409-7414 regions of maize and sorghum

Alexander P. Tikhonov, Phillip J. SanMiguel, Yuko Nakajima, Nina M. Gorenstein, Jeffrey L. Bennetzen, and Zoya Avramova

Efficient export of the glucose transporter Hxtlp from 7415-7420 the endoplasmic reticulum requires Gsf2p

Peter W. Sherwood and Marian Carlson

Protein kinase B/Akt-mediated phosphorylation 7421-7426 promotes nuclear exclusion of the winged helix transcription factor FKHR1

William H. Biggs III, Jill Meisenhelder, Tony Hunter, Webster K. Cavenee, and Karen C. Arden

vi

This content downloaded from 169.229.32.137 on Thu, 8 May 2014 14:13:23 PMAll use subject to JSTOR Terms and Conditions

Contents

The PTEN tumor suppressor homolog in 7427-7432 Caenorhabditis elegans regulates longevity and dauer formation in an insulin receptor-like signaling pathway

Valia T. Mihaylova, Christina Z. Borland, Laura Manjarrez, Michael J. Stern, and Hong Sun

An engineered closterovirus RNA replicon and 7433-7438 analysis of heterologous terminal sequences for replication

T. Satyanarayana, S. Gowda, V. P. Boyko, M. R. Albiach-Marti, M. Mawassi, J. Navas-Castillo, A. V. Karasev, V. Dolja, M. E. Hilf, D. J. Lewandowski, P. Moreno, M. Bar-Joseph, S. M. Garnsey, and W. 0. Dawson

IMMUNOLOGY

Induction of differentiation of pre-NKT cells to 7439-7444 mature Vcrl4 NKT cells by granulocyte/macrophage colony-stimulating factor

Hiroshi Sato, Toshinori Nakayama, Yujiro Tanaka, Masakatsu Yamashita, Yoichi Shibata, Eisuke Kondo, Yasushi Saito, and Masaru Taniguchi

Conformational variants of class II MHC/peptide 7445-7450 complexes induced by N- and C-terminal extensions of minimal peptide epitopes

0. R6tzschke, K. Falk, J. Mack, J. M. Lau, G. Jung, and J. L. Strominger

Cytolytic and IFN-y-producing activities of y6 T cells 7451-7455 in the mouse intestinal epithelium are T cell receptor-:-chain dependent

Masako Kohyama, Masanobu Nanno, Mariko Kawaguchi-Miyashita, Shinichiro Shimada, Mamoru Watanabe, Toshifumi Hibi, Schuichi Kaminogawa, and Hiromichi Ishikawa

MEDICAL SCIENCES

Cancer-specific chromosome alterations in the 7456-7461 constitutive fragile region FRA3B

Koshi Mimori, Teresa Druck, Hiroshi Inoue, Hansjuerg Alder, Lori Berk, Masaki Mori, Kay Huebner, and Carlo M. Croce

Treatment of noninfectious intermediate and 7462-7466 posterior uveitis with the humanized anti-Tac mAb: A phase I/II clinical trial

Robert B. Nussenblatt, Eric Fortin, Rhett Schiffman, Luiz Rizzo, Janine Smith, Paul Van Veldhuisen, Pushpa Sran, Anita Yaffe, Carolyn K. Goldman, Thomas A. Waldmann, and Scott M. Whitcup

Modulation of TEL transcription activity by 7467-7472 interaction with the ubiquitin-conjugating enzyme UBC9

Subhra Ranjan Chakrabarti, Rashmi Sood, Surajit Ganguly, Stefan Bohlander, Zhiyuan Shen, and Giuseppina Nucifora

A critical role for the peroxisome 7473-7478 proliferator-activated receptor (x (PPARax) in the cellular fasting response: The PPAR T-null mouse as a model of fatty acid oxidation disorders

Teresa C. Leone, Carla J. Weinheimer, and Daniel P. Kelly

X inactivation and somatic cell selection rescue female 7479-7483 mice carrying a Piga-null mutation

Peter Keller, Gabi Tremml, Vittorio Rosti, and Monica Bessler

JC virus DNA is present in the mucosa of the human 7484-7489 colon and in colorectal cancers

Luigi Laghi, Ann E. Randolph, D. P. Chauhan, Giancarlo Marra, Eugene 0. Major, James V. Neel, and C. Richard Boland

Silibinin decreases prostate-specific antigen with cell 7490-7495 growth inhibition via G1 arrest, leading to differentiation of prostate carcinoma cells: Implications for prostate cancer intervention

Xiaolin Zi and Rajesh Agarwal

MICROBIOLOGY

Constitutive cell surface association between CD4 7496-7501 and CCR5

Xiaodong Xiao, Lijun Wu, Tzanko S. Stantchev, Yan-Ru Feng, Sophie Ugolini, Hong Chen, Zhimin Shen, James L. Riley, Christopher C. Broder, Quentin J. Sattentau, and Dimiter S. Dimitrov

Virulent Salmonella typhimurium has two periplasmic 7502-7507 Cu, Zn-superoxide dismutases

Ferric C. Fang, Mary Ann DeGroote, John W. Foster, Andreas J. Baumler, Urs Ochsner, Traci Testerman, Shawn Bearson, Jean-Christophe Giard, Yisheng Xu, Gail Campbell, and Tracey Laessig

Murine gammaherpesvirus M2 gene is 7508-7513 latency-associated and its protein a target for CD8+ T lymphocytes

S. Mazher Husain, Edward J. Usherwood, Heather Dyson, Christopher Coleclough, Michael A. Coppola, David L. Woodland, Marcia A. Blackman, James P. Stewart, and Jeffery T. Sample

NEUROBIOLOGY

The neural substrate and temporal dynamics of 7514-7519 interference effects in working memory as revealed by event-related functional MRI

Mark D'Esposito, Bradley R. Postle, John Jonides, and Edward E. Smith

Relationship between presynaptic calcium transients 7520-7525 and postsynaptic currents at single y-aminobutyric acid (GABA)ergic boutons

S. Kirischuk, N. Veselovsky, and R. Grantyn

Interaction between astrocytes and adult 7526-7531 subventricular zone precursors stimulates neurogenesis

Daniel A. Lim and Arturo Alvarez-Buylla

Mice lacking complex gangliosides develop Wallerian 7532-7537 degeneration and myelination defects

Kazim A. Sheikh, Ji Sun, Yujing Liu, Hiromichi Kawai, Thomas 0. Crawford, Richard L. Proia, John W. Griffin, and Ronald L. Schnaar

A brain sexual dimorphism controlled by adult 7538-7540 circulating androgens

Bradley M. Cooke, Golnaz Tabibnia, and S. Marc Breedlove * See Commentary on page 7128

vii

This content downloaded from 169.229.32.137 on Thu, 8 May 2014 14:13:23 PMAll use subject to JSTOR Terms and Conditions

Contents Gap-junctional coupling between neurons and 7541-7546 astrocytes in primary central nervous system cultures

Maira M. Fr6es, Ana Helena P. Correia, Jos6 Garcia-Abreu, David C. Spray, Ant6nio C. Campos de Carvalho, and Vivaldo Moura Neto

Wild-type but not Alzheimer-mutant amyloid 7547-7552 precursor protein confers resistance against p53-mediated apoptosis

Xiao Xu, Daseng Yang, Tony Wyss-Coray, Jim Yan, Li Gan, Yi Sun, and Lennart Mucke

Selective loss of cone function in mice lacking the 7553-7557 cyclic nucleotide-gated channel CNG3

Martin Biel, Mathias Seeliger, Alexander Pfeifer, Konrad Kohler, Andrea Gerstner, Andreas Ludwig, Gesine Jaissle, Sascha Fauser, Eberhart Zrenner, and Franz Hofmann

Somatotopy of the lateral line projection in 7558-7562 larval zebrafish

Daniel Alexandre and Alain Ghysen

PHARMACOLOGY

Nonsteroid drug selectivities for cyclo-oxygenase-1 7563-7568 rather than cyclo-oxygenase-2 are associated with human gastrointestinal toxicity: A full in vitro analysis

Timothy D. Warner, Francesco Giuliano, Ivana Vojnovic, Antoaneta Bukasa, Jane A. Mitchell, and John R. Vane

Activation of erythropoietin receptor in the absence 7569-7574 of hormone by a peptide that binds to a domain different from the hormone binding site

Tatjana Naranda, Kenneth Wong, R. Ilene Kaufman, Avram Goldstein, and Lennart Olsson

PLANT BIOLOGY

Suppression of the heterotrimeric G protein causes 7575-7580 abnormal morphology, including dwarfism, in rice

Yukiko Fujisawa, Teruhisa Kato, Shizuka Ohki, Atsushi Ishikawa, Hidemi Kitano, Takuji Sasaki, Tadashi Asahi, and Yukimoto Iwasaki

AKT3, a phloem-localized K+ channel, is blocked 7581-7586 by protons

I. Marten, S. Hoth, R. Deeken, P. Ache, K. A. Ketchum, T. Hoshi, and R. Hedrich

PSYCHOLOGY

Distribution of tactile learning and its neural basis 7587-7591 Justin A. Harris, Rasmus S. Petersen, and Mathew E. Diamond

Impairments in verb morphology after brain injury: 7592-7597 A connectionist model

Marc F. Joanisse and Mark S. Seidenberg

Social Sciences

ANTHROPOLOGY

Folkecology and commons management in the 7598-7603 Maya Lowlands

Scott Atran, Douglas Medin, Norbert Ross, Elizabeth Lynch, John Coley, Edilberto Ucan Ek', and Valentina Vapnarsky

The early Upper Paleolithic human skeleton from the 7604-7609 Abrigo do Lagar Velho (Portugal) and modern human emergence in Iberia

Cidalia Duarte, Joao Mauricio, Paul B. Pettitt, Pedro Souto, Erik Trinkaus, Hans van der Plicht, and Joao Zilhao * See Commentary on page 7117

CORRECTIONS

BIOCHEMISTRY

Clonal selection and in vivo quantitation of protein 7610 interactions with protein-fragment complementation assays

Ingrid Remy and Stephen W. Michnick

IMMUNOLOGY

Murine natural killer cells contribute to the 7610 granulomatous reaction caused by mycobacterial cell walls

I. Apostolou, Y. Takahama, C. Belmant, T. Kawano, M. Huerre, G. Marchal, J. Cui, M. Taniguchi, H. Nakauchi, J.-J. Fourni6, P. Kourilsky, and G. Gachelin

NEUROBIOLOGY

An empirical basis for Mach bands 7610 R. Beau Lotto, S. Mark Williams, and Dale Purves

Mach bands as empirically derived associations 7610 R. Beau Lotto, S. Mark Williams, and Dale Purves

PSYCHOLOGY

Spatial attention affects brain activity in human 7610 primary visual cortex

Sunil P. Gandhi, David J. Heeger, and Geoffrey M. Boynton

AUTHOR INDEX ix-x

INFORMATION FOR AUTHORS xi-xiii

SIZING WORKSHEET xiv

DOCUMENTATION REPORT xv

COPYRIGHT ASSIGNMENT FORM xvi

SUBSCRIPTION FORM xvii

Cover photograph: A ribbon diagram of Cre recombinase (green) bound to its target on DNA (gold) at the start of the site-specific recombination reaction. Cre cleaves its DNA substrate during the reaction using the active site side chains shown in red. The scissile phosphate in the active site is shown as a blue sphere. The complete recombination assembly contains four of these Cre-half-site complexes, each of which maintains a similar structure throughout the recombination pathway. (Image courtesy of Gregory D. Van Duyne et al. See article on pages 7143-7148, in this issue.)

viii

This content downloaded from 169.229.32.137 on Thu, 8 May 2014 14:13:23 PMAll use subject to JSTOR Terms and Conditions


Recommended