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Great Plains Veterinary Educational Center
The Principles of Animal Hygiene and Preventive Veterinary Medicine
“The faith in “cures” and the practice of dealing with disease problems only after they have arisen, which thousands of years of magic and dosing have firmly established…is antagonistic to disease prevention”
…those more particularly concerned with the food-producing animals must think in terms of hygiene, for their success is in no small measure dependent upon their knowledge of the subject”
Leunis Van Es 1932, University of Nebraska, Lincoln
(slide from Dr. David Smith)
Great Plains Veterinary Educational Center
Biosecurity… in the “real world”?
… can you say
“A-RITS”
Great Plains Veterinary Educational Center
Great Plains Veterinary Educational Center
Understand What We’re Up Against
• How are cattle (the ultimate recyclers) raised?– approximately 100M in U.S. …– 50% from herds less than 30 …– 90% beef & 10% dairy … of the beef …– 2 years from birth to food supply– 40% in breeding herds– 30% grazing – 30% harvested each year– ALL in OPEN AIR ENVIROMENT !!! … wildlife
• deer, coyotes, raccoons, birds, rodents, insects, …
Great Plains Veterinary Educational Center
Biosecurity Basics for Livestock Operations• Biosecurity is a practice designed to prevent the
spread of disease by minimizing the movement of biologic organisms (viruses, bacteria, rodents, etc.) onto and within an operation.
• Biosecurity can be very difficult to maintain because of the very complex interrelationships between management, biologic organisms and biosecurity.
• Biocontainment maybe the only practical control for many diseases.
• While developing and maintaining biosecurity is difficult it is the cheapest, most effective means of disease control available and no disease prevention program will work without it.
Great Plains Veterinary Educational Center
Health - Disease Complex Interactions
Great Plains Veterinary Educational Center
Biosecurity Major Components:
ASSESS Different Biosecurity Risks– RESISTANCE Improvement
ISOLATE from riskTRAFFIC Control
SANITATION – Think Clean
RITS are hurdles threats must cross to cause a concern
Great Plains Veterinary Educational Center
1st … the big “A” … ASSESSMENT• Take a close look at what can go wrong …• Assess the risk of each potential biosecurity
problem …the relative significance & potential• Evaluate potential to PRCE each risk identified!
» Prevent, Reduce, Control, or Eliminate
– Resistance in the herd …– Source into and within the herd … – Exposure within the herd …
• Don’t Gag On A Gnat & Swallow An Elephant!
Great Plains Veterinary Educational Center
2nd …“RITS”Resistance, Isolation, Traffic Control, & Sanitation.
??? Evidence Based ???
–Maximize resistance General Specific
– Isolate from outside & within–Control exposure & potential spread–Clean, Clean & Clean … think CLEAN!
Great Plains Veterinary Educational Center
Biosecurity – Specific Disease Control & Identification
• Risk• Training • Isolation• Traffic Control
• Sanitation• Action Trigger• Rapid Response• Comments
EXAMPLES … BS-Man-07-SpecficDisCont&ID.doc
Great Plains Veterinary Educational Center
Biosecurity Diseases to Consider: • Salmonella• BSE• FMD• BVD-PI• Leptospirosis• Johne’s• Leucosis• Anaplasmosis• Viral calf scours• TB - Bangs
• Johne’s• Leucosis• Anaplasmosis• Viral calf scours• TB – Bangs• Cryptosporidiosis• Coccidiosis, Sarcocystis• Neospora, Toxoplasma• Trichomoniasis, Vibrio • Common Inherent Diseases
IBR, BVD, PI3, BRSV, Mh & Pm Mycoplasma, & Clostridia
Rank significance to different production systemsThreat type: EXTERNAL, INTERNAL, MANAGEMENT
• Staph mastitis??? Mastitis (others???)
• Chronic Wasting Disease (CWD)• Noxious weed• Specific Bioterrorism Issues:
Great Plains Veterinary Educational Center
Secret to Biosecurity Hazard Analysis, Critical Control Points
Justify
Verify
Monitor
Target Activitiesto
Targeted OutcomesPrevent, Reduce Control, Eliminate
Great Plains Veterinary Educational Center
Validate the HACCP Plan Hazard Analysis, Critical Control Points (HACCP):
• "Validation is the scientific & technical basis for CCP determination & CL identified and which control hazards." Validation should include a third party review and should be done regularly (yearly?).
• Validation should reassess potential new hazards.
• Evaluate all production steps, suppliers, equipment use and maintenance, isolation procedures, traffic control and sanitation.
Great Plains Veterinary Educational Center
Risk Management - PECR• Prevent, Eliminate, Control, Reduce
– Resistance … General Specific– SOURCE, EXPOSURE … Additions …– Isolate, test, monitor, re-test …– Traffic Control …– Sanitation …
• Justify Verify Monitor– Is there evidence for control?– Is it getting done?– Is it working? (surveillance testing)
Great Plains Veterinary Educational Center
Sanitation … Disinfectants• Sanitation should stress
CLEAN … not the use of disinfectants• Selection and use of Disinfectants
–Understand the target pathogen–Understand the organic load–Understand the disinfectant properties–Understand disinfectant have been
documented to relate to antibiotic resistance
Great Plains Veterinary Educational Center
Disinfectant Classification
• Hypochlorites:• Iodine and ionophore disinfectants:• Chlorhexidine:• Alcohols:• Oxidizing Agents:• Phenolic disinfectants:• Quaternary Ammonium Compounds:• Aldehydes:
Great Plains Veterinary Educational Center
Disinfectant Properties .
Compound Chlorine0.01-5%
Iodophor0.5-5%
Chlorhexidine0.05-0.5%
Alcohol70-95%
Oxidizing0.2-3%
Phenol0.2-3%
QuaternaryAmmonium 0.1-
2%
Aldehyde1-2%
Examples Clorox Tincture /Provodine
Novalsan VikronS Lysol Roccal-D Wavicide
Bactericidal Good Good Very Good Good Good Good Good V Good
Viricidal V Good Good Very Good Good Good Fair Fair V Good
Envelope Viruses Yes Yes Yes Yes Yes Yes Yes Yes
Non-Envelope Viruses
Yes Yes No No Yes No No Yes
Bacterial Spores Fair Fair Poor Fair F to G Poor Poor Good
Fungicidal Good Good Fair to Good Fair Fair Good Fair Good
Effective in Organic Matter
Poor Fair Fair Fair Poor Good Fair Good
Inactivatedby soap
No No &Yes No No No No Yes No
Effective inHard water
Yes No Yes Yes Yes Yes No Yes
ContactTime (minutes)
5-30 10-30 5-10 10-30 10-30 10-30 10-30 10-600
Residual activity Poor Poor Good Fair Poor Poor Fair Fair
All About Disinfectants
Great Plains Veterinary Educational Center
Disinfectant … Virus TargetsVirus Envelope Virus Envelope Virus Envelope
Bluetongue No Malignant Catarrhal Fever Yes PI3 Yes
Rotavirus No Enteric Coronavirus Yes Rabies Yes
Papillomatosis No Resp. Coronavirus Yes Herpes Mammillitis Yes
Leukemia Yes BVD Yes CowpoxPseudocowpox Yes
Papular Stomatitis Yes BRSV Yes Foot & Mouth No
Vesicular Stomatitis Yes IBR / IPV Yes Lumpy Skin
Disease Yes
Go to End
Great Plains Veterinary Educational Center
Biosecurity Risk … Evaluate• Accessibility• Personnel
training• Reservoir(s)• Isolation• Traffic Flow• Sanitation• Pest Control
Great Plains Veterinary Educational Center
Biosecurity-Security … “what if” Emergency Action Plan
• Assessing the situation:• Is it a disease concern? • Is it a contaminate concern? • Is it an intruder concern? • NOTIFY THE PROPER PERSONNEL• IMPLEMENT QUICK RESPONSE PLAN
– SANITATION … SECURITY Go to End
Great Plains Veterinary Educational Center
http://FarmAndRanchBiosecurity.com