Date post: | 10-Sep-2014 |
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Health & Medicine |
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Restful Nights and Cheerful Days from Food Sourced
Tryptophan
Tryptophan Isolated in 1901Sir Frederick Hopkins
Tryptophan & Serotonin
Tryptophan
Step 1
+ OH
Step 2-COOH
Serotonin
Tryptophan Metabolism Is Light Dependent
Tryptophan
Serotonin
Melatonin
Control Mechanisms in Melatonin Synthesis
Pineal Gland
Pineal Cells•Similar in structure to retinal cells•Secrete melatonin at night•Secrete serotonin in the day
Julius Axelrod
Melatonin-Serotonin & Light
Serotonin
Superiour Cervical Ganglion
Melatonin
Supra Chiasmatic Nucleus
Melatonin-Serotonin & Light
Serotonin
Superiour Cervical Ganglion
Melatonin
Supra Chiasmatic Nucleus
5-HydroxyTryptophan 5-HTP
Tryptophan
Step 1
+ OH
Step 2-COOH
Serotonin
Tryptophan Usage/ 100,000 population
(NEJM 1990)
• Prior to FDA ban 2% of American Households used tryptophan in a regular basis
• The sales growth curve was exponential
0200400600800
1000120014001600
18002000
1980 1984 1988
Males
Females
Tryptophan Ban
• FDA based on cases of EMS• Before and after Showa Denka product• Genetics play a role?• Contamination plays a role?• Most likely some combination of genetics &
contamination
Tryptophan Available From Natural Sources But...
• Protein Sources Rich in Tryptophan decrease brain tryptophan levels.
BBB (Blood Brain
Barrier)
Transport Sites
Transport Sites
Transport Sites(Sites occupied)
• In fact a high protein meal increases blood levels of tryptophan but lowers brain levels
Tryptophan level
Serotonin level
• Carbohydrates prompt the pancreas to create insulin
• Insulin reduces the blood level of all amino acids except for tryptophan
• Tryptophan levels rise relative to other amino acids
Carbohydrate
=
Insulin
• Carbohydrates reduce blood levels of all amino acids except for tryptophan
Finding the right protein
+
=
• Zenbev increases the serotonin level in the brain
• With Zenbev, brain levels of tryptophan go up as blood levels go up
Zenbev Tryptophan=
Anxiety level
Serotonin level
At night, serotonin turns into melatonin
Increase in serotonin
Melatonin =
Sleep StudyNutritional Neuroscience
Chronic Insomnia
RestBites Tryptophan + Carbohydrate Carbohydrate
Protein Source Tryptophan versus Pharmaceutical Grade Tryptophan as an Efficacious Treatment for Chronic Insomnia
Anxiety StudyCanadian Journal Of Physiology & Pharmacology
Social Phobia
RestBites Carbohydrate
Protein-source tryptophan as an efficacious treatment for social anxiety disorder: a pilot study
Eat 1 chocolate ½ hour before bedtime. Try this for three nights and if required, increase by 1 chocolate until the desired effect is achieved.
•90 calories per square•Low Fat (2.5 g)•0 Trans Fats•Caffeine Free•Low Sodium
Ingredients: Partially Defatted Deoiled Organic Pumpkinseed Flour, Organic Agave
Nectar, Sugar, Chocolate Coating, Caramel, Sunflower Oil, Water, Agar, Soybean Oil, Soy Lecithin – Caffeine Free
FAQ’s
• What if I take Zenbev during the day, will I get sleepy?
• Can’t I just eat some pumpkin seeds?
• Why does this have Dextrose in it? • I took some Zenbev last night and I
did not sleep any differently. Why?• What is the difference between this
and l-tryptophan?• Is this different than the tryptophan
that was banned a couple of years ago?
Amide Form
Amine Form
Benefits• Promotes Deep, Restful Sleep and Daytime Calm
• No Hangover effect in the morning
• Return to sleep easily after waking up in the night
• No risk of dependence or tolerance
• Replace Daytime Stress with a sense of calm control
• Organic Ingredients
• Clinically Proven effective
• Patented product