I. MitosisHappy Halloween!

Why do animals shed their skin?

A. Asexual Reproduction

1. When do cells use it?

a) ____________b) ____________c) ____________

2. Cell that reproduce by asexual reproduction reproduce constantly.

B. Mitosis = Asexual Reproduction

1. Division of ____________ __________(body)2. Process in which the nucleusdivides to form 2 new nuclei

Somatic Cell

Daughter Cells

Performed by a single (parent) cell

C. PURPOSE OF MITOSIS:

a. ____________ ____________

. . . OF CHROMOSOMESAS THE PARENT CELL.

b. ____________ ____________ ___

1. TO PRODUCE TWO NEW NUCLEI WITH…

D. What are Chromosomes?

1. ____________ structure of DNA in the cell

2. Located in the ____________ 3. Usually are uncoiled in the form of

____________ 4. Only ____________ when the cell

divides and the chromatin condenses5. Held together by a ____________

E. 5 Stages(do not write)

InterphaseProphaseMetaphaseAnaphaseTelophase

**Animated Video**

1. Interphase• Prior & After Mitosis• ____________ ____________ – ____________ % of cell life spent

here– Cell goes about it’s business

• ____________ ____________ – DNA is duplicated

• ____________ ____________ – Cell prepares to divide

• Cannot see DNA- uncoiled as ____________

2. Prophase

• DNA becomes ____________ as ____________ • Nuclear membrane ____________ • ____________ migrate to opposite

poles• Spindle fibers ____________

Easy to remember- Prophase- prepares for mitosis

3. Metaphase

• Spindle fibers ____________ to centromeres• Chromosomes ____________

at midline of the cell

Easy to remember- metaphase, DNA at middle

4. Anaphase

• Spindle fibers ____________ centromeres• One chromatid goes to each

____________ (they look like V’s)

Easy to remember- anaphase, away they go

5. Telophase

• Chromatids reach ____________ • Mitosis ends when new

____________ ____________ form• Some evidence of cell dividing

Easy to remember- telophase, terminal phase

6. Last part- Cytokinesis• Division of ____________ • Technically not in mitosis–Animal cell- pinching of cell membrane- cleavage–Plant cell- formation of new cell wall- cell plate–DNA becomes non-visible, back to chromatin

• Daughter cells enter G1 period of interphase

What Kind of Cells Does Mitosis Produce?

• Cells with a complete set of chromosomes called diploids

• Humans have 46 chromosomes or 23 pairs of chromosomes

• Human diploid # = 23• Most cells are diploid

Cancer

• Uncontrollable mitosis (no G1)– Cells cease to do what

they are supposed to be doing in favor of dividing.

• Cancer does not “poison” your body…

Henrietta Lacks• 1951, a poor 31 Year old African

American mother of 4 was dying of cervical cancer @ Johns Hopkins Hospital– Dr. George Gey- sampled some of the

cancerous cells, found they could live indefinitely and multiply outside the body

– She died 6 months later, but cells still live on

• HeLa cells– Used to study many different diseases– Polio Vaccine– How to transport cells

The Mitosis Shuffle! • First, lets watch:

University of Madison Mitosis Shuffle

• Your turn!“The Hustle” by Van McCoy