1. Inflammation

2. 1.Function (phagocytosis) Phagocytic cells Monocytes (histiocytes, macrophages) PNL (particularly neutrophils) Non-phagocytic cells Lymphocytes Plasma cells 3. Acute Inflammatory Cells PNL Chronic Inflammatory Cells Macrophages Histiocytes Monocytes Lymphocytes Plasma cells 4. Neutrophils 5. lymphocytes 6. eosinophils 7. Basophils 8. Lymphocytic thyroditis 9. fibroblast A fibroblast is a type ofcell that synthesizes the extracellular matrix and collagen, the structural framework (stroma) for animal tissues, and plays a critical role in wound healing. 10. Fibroblast cells 11. Plasma cells Plasma cell with distinctclear perinuclear region of the cytoplasm containing a large number of Golgi bodies 12. Reticuloendothelial cells are phagocytic; i.e., they canengulf and destroy bacteria, viruses, and other foreign substances. A histiocyte is an animal cell that is part of the mononuclear phagocyte system (also known as the reticuloendothelial system or lymphoreticular system). The mononuclear phagocytic system is part of the organism's immune system. The histiocyte is a tissue macrophage or a dendritic cell. 13. Giant cells/ A giant cell is a mass formed by the union of severaldistinct cells (usually macrophages).It can arise in response to an infection, such as from tuberculosis, herpes, or HIV, or foreign body. Epithelioid cells Are activated macrophages resembling epithelial cells elongated, with finely granular, pale eosinophilic (pink) cytoplasm and central, ovoid nucleus (oval or elongate), which is less dense than that of a lymphocyte 14. Caseous necrosis 15. Giant cells 16. Epitheloid cells 17. Serous inflamtion 18. Pericardial thickening due to fibrinous inflammation 19. Fibrinous infammation 20. Fibrinous infammation 21. Heart: fibrinous pericarditis This is a classic exampleof fibrinous inflammation involving the visceral pericardium (bread and butter pericarditis). Fibrinous inflammation is due to increased vessel permeability leading to the leakage of a sterile exudate with fibrin on to the surface of the heart. 22. Purulent inflammation 23. Lung Abscess An abscess is acollection of pus that has accumulated within a tissue because of an inflammatory process in response to either an infectious process or other foreign material. 24. Mucoid or Catarrhal Inflammation Mucoid or CatarrhalInflammation Illustrated is an up side-down section of colon which exhibits excess secretion of mucus (M) into the colonic lumen. 25. Serous inflamation disruption of epidermisat the basal level leaving a clear-fluid-filled bullous lesion 26. Normal lung: appears as mostly empty space. Alveoli have thin walled with a thin epithelial cell through which oxygen and carbon dioxide diffuse into the capillary lumen 27. Sub arachnoid space 28. Normal liver3. Chronic viral hepatitis Caused by: Chronic viral hepatitis (hepatitis B virus)(Characteristic features) Chronic inflammatory infiltrate is limited to the portal area 29. Chronic inflamation 30. What is a Granuloma A granuloma is a localized mass of granulation tissuewith aggregations of chronic inflammatory cells 31. Granuloma 32. Granulation tissue