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Introduction to Microfabrication Nick Ferrell Biomedical Engineering.

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Introduction to Microfabrication Nick Ferrell Biomedical Engineering
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Page 1: Introduction to Microfabrication Nick Ferrell Biomedical Engineering.

Introduction to Microfabrication

Nick FerrellBiomedical Engineering

Page 2: Introduction to Microfabrication Nick Ferrell Biomedical Engineering.

Basics of Microfabrication

• Developed by microelectronics industry• Adapted for silicon MEMS• Refined for nanoscale fabrication• Extended to polymer micro/nanofabrication

Page 3: Introduction to Microfabrication Nick Ferrell Biomedical Engineering.

Basic Processing-Photolithography

Coating and Exposure

Page 4: Introduction to Microfabrication Nick Ferrell Biomedical Engineering.

Latent Image Formation

Develop-Positive Tone Develop-Negative Tone

Page 5: Introduction to Microfabrication Nick Ferrell Biomedical Engineering.

Limits of Photolithography

Minimum Features Size α Exposure Wavelength

Spectrum for Hg Arc Lamp (365 and 436 nm)

http://www.cairnweb.com/tech/tech_lamp2.html

Page 6: Introduction to Microfabrication Nick Ferrell Biomedical Engineering.

Nanofabrication

Excimer Lasers: KrF (248 nm) ArF (193 nm)

F2 (157 nm)

X-rays, EUV (10-40 nm)E-beam: (.0037 nm @ 100kV)

X-ray (70 nm) E-beam (43 nm)Ito, Okazaki, Nature 408 (2000), 1027-1031.

Page 7: Introduction to Microfabrication Nick Ferrell Biomedical Engineering.

Polymer Micro/Nanofabrication

Polymer Properties•Wide range of physical and chemical properties• Biocompatible• Cheap

Techniques• Hot Embossing• Injection Molding• Soft Lithography

- Microtransfer Molding- Microcontact Printing- Micromolding in Capillaries- Sacrificial Layer Micromolding

Page 8: Introduction to Microfabrication Nick Ferrell Biomedical Engineering.

Hot Embossing

J. Narasimhan, I. Papautsky, J. Micromech. Microeng. 14(2004), 85-105

Page 9: Introduction to Microfabrication Nick Ferrell Biomedical Engineering.

Soft Lithography

Figure 2. Chemical structure of PDMS.

-Cheap-Easy-Quick-Robust

RapidPrototyping

Y. Xia, G.M. Whitesides, Soft Lithography, Angew. Chem Int. Ed. 37(1998), 550-575.

Page 10: Introduction to Microfabrication Nick Ferrell Biomedical Engineering.

Y. Xia, G.M. Whitesides, Soft Lithography, Angew. Chem Int. Ed. 37(1998), 550-575.

Soft Lithography

Page 11: Introduction to Microfabrication Nick Ferrell Biomedical Engineering.

Microcontact Printing

Page 12: Introduction to Microfabrication Nick Ferrell Biomedical Engineering.

Sacrificial Layer Micromolding

Page 13: Introduction to Microfabrication Nick Ferrell Biomedical Engineering.

Multi-layer Patterning

HEAT (110° C)

SU8

PDMS

PPMA

Page 14: Introduction to Microfabrication Nick Ferrell Biomedical Engineering.

PDMS

Page 15: Introduction to Microfabrication Nick Ferrell Biomedical Engineering.

OH OH OH

CH3 CH3

CH3 CH3CH3

CH3 CH3

O2 Plasma

CH3 CH3 CH3 CH3 CH3 CH3 CH3 CH3CH3

OH OH

OH OH OH

OH OH

OH OH OH OH OH OH OH OH OH

Si

OSi

Si

OSi

Si

OSi

Si

OSi

PDMS Bonding


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