NoReÁreCo TítFrohu
ReThint I h i) 1)SN2)hiinvpo ii) 1)2)wa3)ThMcoEv iii)1)2)I wstinv iv)1)deanIn2)3)
ReI chuniCein abIn
MDY
ombre: ferencia: ea Científicaorreo Electró
tulo: om the largest uman genome f
sumen de lahe aim of my rterest in geneti
have concentrat
Description of Analysis of theNP data. Analysis of thghlighted by Thvestigators froopulation subst
Inference of de Quantification Estimation of as included in t Estimation of he study was undo (http://wonsequences ofvolutionary Biol
) Detection of t Analysis of the Development was involved inudent under mvestigators from
) Development Development eveloped is beinncient DNA samstitute. Analysis of the Development
sumen del Ccompleted my Puman populatione years, I haventre, includingteaching of M
bout evolution. itiative), Schied
MINISTERIO
E ECONOMÍACOMPETITIV
LAO GRURYC‐2013
a: Biología Fnico: osca
continent to tfor the mapping
a Memoria: research is theic epidemiology
ted my researc
population sube population su
e population she New York Tim the Departmtructure in sam
emographic pan of the proportdemographic pthe PhD of a Phdemographic pcommented awww.elmundof these demoglogy Institute (U
the fingerprint oe genetic variatof a new statis the design of tmy supervision m the Departm
of new statisti of new algorng applied in amples. Furtherm
e proportion of of new algorith
Currículum VPhD at Universions, during whve been involveg the thesis co‐saster and PhD I have been indam Vlaardinge
A VIDAD
UESO, OSCA3‐14797 Fundamentaar.lao@gmai
he smallest pog of complex di
e detection andy applications.
ch in:
bstructure of seubstructure an
ubstructure primes (http://wwment of Obstetples from Euro
rameters that stions of geneticparameters in D student that parameters andt El Pais (http.es/elmundo/2graphic charactUPF‐CSIC).
of selective preion of genes putic for estimatithe project andin collaboratio
ment of Internal
cal methods / aithms for ascen international more, I am curre
recent genetichms for detectin
Vitae: idad Pompeu Fich time I also ed in postdoctosupervision of tcourses relate
nvolved in diffeen and Universi
AYUDASCONVO
AR
l y de Sistemil.com
pulation: boostiseases
d analysis of h
veral human dad genetic ‐ geo
esent in Europww.nytimes.corics and Gynaepean ancestry.
shaped the genc ancestry from East Asian andI co‐supervisedd geographic idp://sociedad.elp012/12/06/uniteristics in the
essures in the hutatively associang phenotypic‐d the co‐supervon with investiMedicine in a p
algorithms for dertaining ancescollaboration wently extending
ancestry in diffng fine populat
abra in Barcelostudied at theoral research itwo PhD studend to Human Gerent projects fity of Cologne.
S RAMÓN YOCATORIA
mas
ting detection o
human genetic
atasets: ographic associ
pean populationom/2008/08/13ecology and the
netic variation: Han and Melad Oceanian popd. dentification of pais.com/socieon_europea/13e health of the
uman genomeated to human‐genetic co‐varivision of PhD stigators from thphenotype with
detecting popustry informativewith investigatg the method in
fferent recentlytion substructu
ona with a these Dipartimento n the Forensic nts and one Maenetics, and I ainanced by the
Y CAJAL A 2013
of genetic popu
population su
iation present
ns for the first 3/science/13vise Department o
nesian populatpulations using
the origin of tdad/2012/12/0354821995.htme Romani peop
: pigmentation iation at a poputudent Isabel Mhe Evolutionaryh health implica
lation substruce markers in hors from the Nn collaboration
y admixed popure using any typ
is entitled Natudi Biologia ed Molecular Bio
aster student. Dam the co‐supeForensic Geno
SDD
SDE
DDC
SDP
ulation substru
bstructure and
in Dutch popul
time using micual.html?_r=0)of Internal Med
ions in the Polygenome whole
he proto‐Roma06/actualidad/1ml) newspaperple in collabora
in order to deteulation level anMendizabal. Thiy Biology Institations.
ture in the humhuman populatatural History Mwith investigat
ulations, such aspe of genetic va
ural history of mEvoluzione of logy DepartmeDuring this periorvisor of a jourmics Center Ne
SECRETARÍA DEDE INVESTIGACDESARROLLO E
SECRETARÍA GEDE CIENCIA, TECE INNOVACIÓN
DIRECCIÓN GENDE INVESTIGACCIENTÍFICA Y TÉ
SUBDIRECCIÓN DE RECURSOS HPARA LA INVEST
ucture and posi
d genetic ances
lation by mean
croarray SNP d. I am currentlydicine (Erasmu
ynesian populate SNP microarr
ani using whole1354809333_60rs. I am curreation with inve
ect positive selend application ts research is fotute. I am also
man genome: tions. The statMuseum of Dentors from the E
s Argentineansariant.
mendelian and Università di Fent of Erasmusod I participaternal club for Phetherlands (Net
E ESTADO IÓN INNOVACIÓN
ENERAL CNOLOGÍA
NERAL IÓN
ÉCNICA
GENERAL HUMANOS TIGACIÓN
tive selection i
stry, with parti
ns of whole gen
data. This studyy collaboratings MC) for dete
tion. ray data. This s
e genome SNP 05563.html) anently analyzingestigators from
ective sweeps.o the pygmy heollowed by a Mo collaborating
tistical framewnmark to be usEvolutionary Bio
or U.S. popula
complex diseaserrara. For thes University Meed on a regular hD medical studtherlands Geno
n the
icular
nome
y was with ecting
study
data. nd El g the m the
eight. aster with
work I sed in ology
tion.
ses in e past edical basis dents omics
MhupogescInpo20th(HinvGeI hcoprNaAlchpoabco
MDY
y research hasuman populatioopulation substenome. My woientific projectsparticular, duropulations (Cur008), applying te most suitabl
Hum Mut 2010)volved in the aenet 2007) or thave collaboratollaborating witroject or providatural History Ml these achievehapters about topularizing sciebout published olonise‐asia.htm
MINISTERIO
E ECONOMÍACOMPETITIV
s equipped me on history. I amtructure, recovork at Forensics. ring my postdocr Biol 2008 & 2the state‐of‐artle sets of ance), forensic geneanalysis of posihe pygmy heighted in several th investigatorsding statistical Museum of Denements qualify the subject in dence (http://bwworks by othe
ml#.Uu959fl5Oi
A VIDAD
with consideram used to work ver estimations Molecular Bio
c I have analyse2012), the Dutct of algorithms stry informativetics (Ann Humtive selection iht (Hum Genet international ps from differentadvice) in col
nmark. me as an expedifferent on‐linwm.trefcon.nl/er scientists (hU, http://news
AYUDASCONVO
able expertise iwith data froms of the demoology has allow
ed the genetic dch population (from the field ve markers (Amm Genet 2010) an the human g2012).
projects, whoset departments ollaborations wi
ert in the field e Encyclopaedi/media/pdf/Evottp://www.new.sciencemag.or
S RAMÓN YOCATORIA
n human popum whole genomographic paramwed me to dev
diversity prese(Inv Genet 201of population gm J Hum Genetand genetic epgenome with im
e results have bof the Erasmusith investigator
of human popias (Enc. Life Scolutie%20zit%2wscientist.com/rg/biology/2014
Y CAJAL A 2013
ulation genetic me scans, applymeters and detvelop my skills
nt in SNP micro3) and Oceanicgenetics. I havet 2006), with didemiology (J Cmplications in v
been published MC. At internars from the Ev
ulation geneticcien. 2009, Enc0in%20je%20g/article/mg2174/02/black‐dea
SDD
SDE
DDC
SDP
data analysis aing and develotect signals of to implement
oarray data of nc populations (e also developedirect applicatioClin Endocrinol visual traits suc
d in high impacational level, I avolutionary Bio
cs, as acknowlec. Social & Behaenen.pdf) and 29055.200‐sweath‐left‐mark‐hu
SECRETARÍA DEDE INVESTIGACDESARROLLO E
SECRETARÍA GEDE CIENCIA, TECE INNOVACIÓN
DIRECCIÓN GENDE INVESTIGACCIENTÍFICA Y TÉ
SUBDIRECCIÓN DE RECURSOS HPARA LA INVEST
and a strong baoping statisticalf positive select, manage and
non‐Romani anCur Biol 2010 ed new techniqons in human Metab 2011). ch as skin pigm
ct factor journam involved (eitology Institute
edged by the inav Scien. 2014) interviews ineat‐mutation‐muman‐genome
E ESTADO IÓN INNOVACIÓN
ENERAL CNOLOGÍA
NERAL IÓN
ÉCNICA
GENERAL HUMANOS TIGACIÓN
asis on statistics techniques to ction in the hu supervise my
d Romani Euro& Am J Hum Gues for ascertapopulation genFinally, I have
mentation (Ann
als. Nowadays ther supervisin(UPF‐CSIC) and
nvitations to w), a chapter of n scientific joumay‐have‐helpe?rss=1).
s and infer uman own
opean Genet aining netics been Hum
I am g the d the
riting book urnals ed‐us‐
NoReÁreCo TítM
ReThasprgacosilsimis thyeeseureinde
ReBadeca(2an(SFuporea Mtimsubare
MDY
ombre: ferencia: ea Científicaorreo Electró
tulo: echanistic insig
sumen de lahe goal of my ssociated to carogression, we ains are indepeorrelation with encing of discrmilar implicatioa two‐step mee replicative heast, we showessential C‐termukaryotes. In aeleasing abortivactivated by Cependent qualit
sumen del Cachelor degree egree in geneticancer. Superviso002), Oncogennd views on theydney, Australiurthermore, baostdoc studies aesulted in two pfirst author. Tholecular Cell. Bmes. From my uccessful collabackground spaespectively. Con
MINISTERIO
E ECONOMÍACOMPETITIV
FRIGOLARYC‐2013
a: Biología Fnico: jord
ghts into genom
a Memoria: PhD was to fi
ancer are globadeveloped a noendent processgenomic instabrete genes. Howons as loss of hechanism. Durinelicase. Duringed that the recinal domain ofaddition, we fove reactions thCyclin Dependety control of or
Currículum Vin Biology, Unics, Universitat dor: Miguel Ange and Human Me same journaia). I stayed fosed on the pubare on chromopublished paperhe Nature articBoth of my PhDthirteen years borations with ns from epigensequently, I fe
A VIDAD
A MAS, JOR3‐12727 Fundamentadi.frigola@ca
mic replication
ind out epigenal hypomethylaovel techniqueses and contribility, regardleswever, we showeterozygosity inng G1 the replic the first step, ruitment of thf Mcm3. Intereound that ATPhat could compent Kinase, therigin licensing co
Vitae: versitat de Girode Barcelona (2gel Peinado. FrMolecular Genel and was recor a year on heblished results some replicatiors, one review icle has been ciD and postdoc sof research exother scientis
enetics in humel highly qualifi
AYUDASCONVO
DI
l y de Sistemncer.org.uk
netic changes aation and regio, called Amplifibute in differes of p53 statuswed that this lon cancer. My pcation origins aran inactive hee helicase ontoestingly, this doP hydrolysis is promise the in helicase is alsontributing to p
ona (1997), bac2005). Awardedom my thesis etics (2005) andmmended by Fr laboratory an(Nature Geneton in S. cerevisn Current Opinited in Faculty studies have beperience, eightsts and I haveans to biocheied and confide
S RAMÓN YOCATORIA
mas
associated to conal promoterication of Interent ways to ca. Concerning thoss of gene expostdoc studies re licensed andlicase is loadedo origins, arguaomain is consenot only criticantegrity of the so released in precise once pe
chelor degree ind with special dI published fived Cancer ReseaFaculty 1000. Dnd it was the btics, 2006), we iae at the Londnion in Cell Biolo1000 and it ween presented t have been abe gained expeemistry in yeasent to establish
Y CAJAL A 2013
colorectal tumor hypermethylarMethylated Sitancer progressihe regional hyppression can ocare on chromo
d in S‐phase repd onto origins aably the earlieserved from yeaal for the helicorigins. FurtheATP depende
er cell cycle rep
n Biochemistry,doctorate (2006e different paparch and NaturDuring my PhDbeginning of a submitted a U
don Research Inogy (2012) and
was highlighted in several interbroad (Sydney arience with bost, complemen my own resea
SDD
SDE
DDC
SDP
origenesis. Theation. To evalutes (AIMS). We ion. Specificalermethylation,cur through lonosome replicatioplication starts. and is not activst step in the lost to humans, case loading, itermore, if the nt manner. Thlication.
, Universitat Au6). Thesis title: Epers, all as a fire Genetics (200studies, I decilong collaboratUS‐based patennstitute with Dran article formin Nature Revrnational meetiand London). Doth, mammalianting my degrerch group.
SECRETARÍA DEDE INVESTIGACDESARROLLO E
SECRETARÍA GEDE CIENCIA, TECE INNOVACIÓN
DIRECCIÓN GENDE INVESTIGACCIENTÍFICA Y TÉ
SUBDIRECCIÓN DE RECURSOS HPARA LA INVEST
e main DNA muate their pote found that glolly, global hypo, previously wasng range epigeon. In eukaryotAt the heart ofvated until S‐phoading reactionsuggesting simt also plays anlicensing com
his result revea
utònoma de BaEpigenetic alterst author. Nuc06). This last paided to visit prtion between ht, which I am tr. John diffley. mat paper in Naview in Molecuings and they hDuring this timean cells and yees in Biology
E ESTADO IÓN INNOVACIÓN
ENERAL CNOLOGÍA
NERAL IÓN
ÉCNICA
GENERAL HUMANOS TIGACIÓN
methylation chaential role in tuobal losses and omethylation hs associated to netic silencing,tes, DNA replicf this regulationhase. Using budn, it depends omilar roles in hn important roponents have als a novel ATP
rcelona (1999)rations in colorcleic Acids Reseaper deserved ofessor Susan her and Dr.Peinthe first authorSo far, my worture (2013), bolar Cell Biologyhave been citede I have establiyeast. My scie and Biochem
anges umor local has a local with ation n lays dding on an igher le on been Pase‐
. PhD rectal earch news Clark nado. r. My k has oth as y and d 473 ished ntific
mistry,
NoReÁreCo TítInv
ReMnagaTwmTh(Dknfoacamm1. m2. obreth3. mphin w4. a Alceth
ReI c
GePrwDuauco
regra tEadadihafo(C
MDY
ombre: ferencia: ea Científicaorreo Electró
tulo: vestigating the
sumen de laost of my reseatural developmametogenesis awo key processutations and 2hese two proceDSBs) on the DNnown as the DNor checkpoints actively promotemount of DSBs eiotic DDR andI am developiethod as a toolI have shown
bserved that melevant regions at differentiallyInitiation of mapped, little ishosphorylation.a timely mannill be able to woSeveral meiotikey in finding ntogether, the sells. Furthermoe current adva
sumen del Ccurrently hold
enome Damagerof. Anthony Caill fund the 36 muring the first 1uthored two maorresponding a
ecombination (Croup. There, I athird manuscriparlier I held twoamage responsscovered the fias been extensocused my reseaCarballo and Cha
MINISTERIO
E ECONOMÍACOMPETITIV
CARBALLRYC‐2013
a: Biología Fnico: jac5
essential funct
a Memoria: earch experiencmental processa specialized ceses are essent) to accuratelyesses require mNA. This is a haNA damage respand maintenances homolog reccatalysed. Wit to understanding a SILAC bal to acquire higthat phosphor
mutations that pin human and y activates the
meiotic DSBs has known of ho. I have been aner, but most imork on my hypoc genes have bnew targets to fstudy of meiosire, the approacnce in those ar
Currículum Va New Investig
e and Stability Carr, the directormonths that thi15 months I haanuscripts duriuthor of a pa
Carballo et al. ssessed the impt that will be so postdoc posite (DDR) in yeasirst meiosis speively cited by march on the mea, 2007).
A VIDAD
LO GONZAL3‐13950 [email protected]
tions of the DNA
ce has been focses like gametoll division knowial during meio segregate hommeiotic recombazardous proceponse (DDR). Duce of genome scombination byth this solid exp their moleculased phospho‐ph quantity of darylation of the sprevent interacyeast SC proteiDDR in meiosisppens only in sow their expreble to predict tmportantly, theothesis using Chbeen identified afight against sois can offer numch from a diffeeas.
Vitae: gator Research
Centre part of tr of this prestigis fellowship lasve successfullyng that period aper published
2013). I was alplication of Ausubmitted this mtions at the prest and mouse. ecific DDR adapmy peers in theeiotic functions
AYUDASCONVO
LEZ‐CORRO
l y de Sistemc.uk
A Damage Resp
cussed in tryingogenesis. Defecwn as meiosis taosis: 1) to swamologue chromination to occuess that can leauring my years stability. I have y ensuring repperience my fuar mechanisms proteome wideata that will be synaptonemal tion of SC protins required fors in yeast and hselected regionssion is regulathe existence oeir expression ishIP‐Seq methodas oncogenes rme cancers. merous advanterent angle to c
Grant research
the University oious institute. Csts. y directed a stuand a third onein PLoS Gene
so second authrora kinase durmonth. estigious NationThere I publishptor which wase field due to is of ATM/ATR k
S RAMÓN YOCATORIA
OTO, JESUS
mas
ponse during G
g to understancts in the secoakes place. Meap genetic infomosomes and siur and this is iad to genome ias PhD studenshown the impair using the ruture research and possible ime screen metho developed in scomplex (SC) isteins with ATR r such interactiumans. ns in the genomated. I have shof two differents likely controlldology. recently. Identif
tages and compclassic problem
h fellowship aw
of Sussex� camCurrently I have
udent for his Me is currently inetics where I i
hor in a paper ring meiotic ch
nal Institute forhed my main ws phosphorylateits high relevankinases. A summ
Y CAJAL A 2013
ametogenesis a
d how cells maond one can leiosis is requiredormation betweister chromatidnitiated by thenstability if unrt and postdoc Iplication of the right DNA tempwill be based omplications in cod to identify iseveral projectss required for kinase fail to ton. With this p
me called hotsphown that ATMt populations oed by the meio
fication of meio
plementary anams in biomedicin
warded by the
mpus in UK. The my own budg
sC thesis as pan preparation. Aidentified a ne
published in Peckpoint arrest
r Medical Reseawork as lead auted by ATM/ATnce, not just inmary of this wa
SDD
SDE
DDC
SDP
and Cancer
aintain genomead to disorderd to reduce theeen parental cds respectively e catalysis of prregulated. DSB extensively stuDDR in monitoplate. The DDRon the identificancer. These arin vivo meiotics in the future. meiotic checkprigger checkpoproject I aim to
pots. Whereas mM/ATR modulaf DSB‐hotspotsotic DDR. In col
otic‐DDR genes
alyses to those ne could yield a
Medical Resea
ere I perform iget for research
art of the of unAmong those pew target of A
PLoS ONE in cot (Newnham et
arch in London.thor in the presR kinases. (Caryeast, but alsos published in
SECRETARÍA DEDE INVESTIGACDESARROLLO E
SECRETARÍA GEDE CIENCIA, TECE INNOVACIÓN
DIRECCIÓN GENDE INVESTIGACCIENTÍFICA Y TÉ
SUBDIRECCIÓN DE RECURSOS HPARA LA INVEST
e stability afterrs like infertilite number of chchromosomes wto avoid aneuprogrammed DoB repair is moniudied the DDR oring meiotic DSR is also criticacation of novel re may aims forc phospho‐prot points. In my point response. Iidentify the mo
most of these ates meiotic DSs that are regullaboration with
with oncogeni
e extensively pea more synerg
arch Council (M
ndependent reh consumables
niversity MSc. ppublications, I wATR, Rec114, r
llaboration witt al. 2013). I am
. My research fstigious journaballo et al. 200o in humans. Da review in Chr
E ESTADO IÓN INNOVACIÓN
ENERAL CNOLOGÍA
NERAL IÓN
ÉCNICA
GENERAL HUMANOS TIGACIÓN
r DNA damage y or cancer. Dhromosomes towithout introdploidies in gamouble Strand Bitored by a netand how it is crSB repair and hl in modulatingcomponents or the future: teins. I will use
reliminary studhave identifiedolecular mecha
hotspots have SBs at hotspotated and expreh a group in Jap
c potential cou
erformed in somistic contributio
MRC) working a
esearch endoweand equipment
program. I havewas the first anrequired to me
th Eva Hoffmanm currently fina
focused on thel Cell. In that w08). This manusDuring my postromosome rese
or in uring o half. ucing
metes. reaks twork ritical ow it g the of the
e this
dies, I d the anism
been ts via essed pan, I
uld be
matic on to
at the
ed by t that
e also d co‐eiotic
nn�s lizing
DNA work I script tdoc I earch
Inph
DuloDuda20apI wpaI hmofW
MDY
collaboration hosphatase and
uring my postdcated in Milan,uring my PhD samage and cell003a, Perez‐Talpoptosis‐like dewas accepted toarticipated as inhave extensiveultidisciplinary f the commonly
With my experie
MINISTERIO
E ECONOMÍACOMPETITIV
with Luis Aragd rDNA segrega
oc training I vis Italy to learn nstudies, I learnl cycle progresslavera et al. 20eath in plants ino present my wnvited speaker e experience inlab. I have expy used bioinformnce I'm now in
A VIDAD
gon�s group tion (Machín et
sited Luis Aragonew techniquest how ionizing sion in plant ce003b and Gimen response to sework to an intein several meetn many molecuperience in planmatics tools. I han excellent po
AYUDASCONVO
from Imperial t al. 2006).
on�s group in s relevant to myradiation affecells was used aenez‐Abian et aevere DNA damrnational audietings in UK. ular, biochemicnts, yeast, bactehave also traininosition to creat
S RAMÓN YOCATORIA
College we p
London and alsy research. cts cell cycle pas part of four al. 2004). One mage (Carballo eence in 5 Gordo
cal, cytological,eria, and cell linng in areas invoe quality resea
Y CAJAL A 2013
ublished a pap
so visited Profe
roliferation. Mypublications (Gof the highlighet al. 2006). on Research Co
and immunohnes. I have basiolving systems rch and attract
SDD
SDE
DDC
SDP
per in the Jour
ssor Marco Foi
y optimization Gimenez‐Abianhts of my PhD
onferences in U
histochemical tc training in biolevel techniquefunding.
SECRETARÍA DEDE INVESTIGACDESARROLLO E
SECRETARÍA GEDE CIENCIA, TECE INNOVACIÓN
DIRECCIÓN GENDE INVESTIGACCIENTÍFICA Y TÉ
SUBDIRECCIÓN DE RECURSOS HPARA LA INVEST
rnal of Cell Bio
iani�s group a
of the irradiatn et al. 2002, Presearch was t
US and 5 EMBO
techniques reqo‐statistics andes like ChIP‐CHI
E ESTADO IÓN INNOVACIÓN
ENERAL CNOLOGÍA
NERAL IÓN
ÉCNICA
GENERAL HUMANOS TIGACIÓN
ology about C
t the IFOM inst
tion to analyze Perez‐Talavera the identificatio
O conferences.
uired for runn knowledge of P/Seq.
DC14
titute
DNA et al. on of
I also
ing a most
NoReÁreCo TítPla
ReCefounintDuthpaMprinvpaplco
RePU1.2.3.4.5.6.7.8.9.1011121314151617Pa1. GR
‐ P
en
‐ Es‐ P‐ F20‐ A
MDY
ombre: ferencia: ea Científicaorreo Electró
tulo: ant cell biology
sumen de laells continually or correct cell dnder investigatterconnectionsuring my PhD I em, I leaded neathogens. Morey work as posrojects aims tovolved on cell athway for clatant developmeonnecting horm
sumen del CUBLICATIONS ‐ Sánchez‐Rodr‐ Sanchez‐Rodr‐ Sánchez‐Rodr‐ Wu XN, et al. ‐ Torres MA, et‐ Ramos B, et ‐ Sánchez‐Rod‐ Sánchez‐Rod‐ Endler A., et a0.‐ Sánchez‐Rod1.‐ Sánchez‐Rod2.‐ Sánchez‐Rod3.‐ Llorente F, e4.‐ Molina A, et 5.‐ Hernández‐B6.‐ Stein M, et a7.‐ Llorente F, atents ‐ Method for In
RANTS AND AW
Postdoctoral Co
n el extranjero�Postdoctoral Fscudero, Spain. Postdoctoral FeFellowship for 006 Academic Awar
MINISTERIO
E ECONOMÍACOMPETITIV
SANCHERYC‐2013
a: Biología Fnico: c.sa
y during develop
a Memoria: perceive signaivision and difftion. In my res of its structureidentified and ew areas of reseover, in collabotdoctoral reseao understand twall arquitectuhrin‐mediated ent and its ev
mone signaling a
Currículum V
ríguez C¥, Gaderiguez C¥, Krishríguez* and Per(2013) Mol Celt al. (2012) Molal., (2013) Mol ríguez C, et al. ríguez C¥, Delgal. (2010) Naturdríguez C, et aldríguez C, et al.dríguez C, et alet al. (2008) Mo al. (2008). PhyBlanco C, et al. al. (2006) Plantet al., (2005) P
ncreasing patho
WARDS
ontract �Prog
�. Ministerio d
Fellowship �BDec 2008
ellowship. Fundshort term res
rd (First Class H
A VIDAD
Z RODRIGU3‐13933 Fundamentanchez@mpim
pment and in re
ls from other cerentiation. Plasearch career es and pathwaycharacterized psearch with theoration with a carcher is mainlhe cellulose prure. This work hendocytosis in volutionary signand cell wall syn
Vitae:
eyne A¥, et al. Anamoorty P¥, ersson S. Book chl Proteomics. O Plant Microbe Plant Pathol., J(2012) Plant Ceado‐Cerezo, Mre chemical bio. (2010) Trends (2010) Book ch. (2009) Mol Plaol. Plant., May;ytoma, 192: 43 (2007) Plant Ct Cell, Mar; 18(3lant Journal, Ju
ogen resistance
rama Nacional
de Ciencia en In
ecas de invest
ación Ramón Aearch at Carne
onors) 1998‐20
AYUDASCONVO
UEZ, CLARA
l y de Sistemmp‐golm.mp
esponse to stre
ells and from tants have evolvI apply multid
ys, and the simiprominent playe aim of elucidacolleague, I staly focused on eroduction and has led to the iplants, which inificance in eunthesis, and am
Accepted in Celet al. Accepted hapter. Under eOct 12(10):2856Interact. Jun; 2Jan;14(1):44‐57ell, Feb;24(2):58¥, et al. (2012) logy, Dec; 6(12s Plant Sci., Mahapter. ISBN 97ant Microbe Int1(3):496‐509 ell, Mar; 19(3):3):731‐46. l;43(2):165‐80
e in plants. Ref.
de Recursos Hu
novación, Spain
tigación en un
Areces, Spain. Jegie Institution
003. Universida
S RAMÓN YOCATORIA
mas pg.de
ess
heir environmeved particular mdisciplinary apilarity to other yers in plant resating the role ofrted a new studelucidating howassembly in midentification ois being publishukaryotes. In am currently purs
l (Tentatively: 1in Annals of Boedition (Wiley‐B6‐73 26(6):686‐94 7 89‐607 Mol. Plant, Jan
2):883‐4 ay;15(5):291‐3078‐0‐9654625‐6teract., Aug;22
890‐903.
. Nm: PCT/EP20
umanos de Inve
n. Nov 2008
niversidades o
Jun 2008 of Washington
ad Politécnica d
Y CAJAL A 2013
ent, which is esmechanisms to proaches to seukaryotes. sponse to necrof the cell wall ady on plant vacw plant cell wamuro. At the saof a unique evohed in Cell. I amaddition, I havsuing this topic
156/4;Feb 14). ¥otany. ¥Equal coBlackwell). *Co
n;5(1):98‐114. ¥
01 6‐3 (8):953‐63
013/077076
estigación, sub
centros en el
n, Stanford, US
e Madrid, Spain
SDD
SDE
DDC
SDP
sential for the adapt to their ehed some ligh
otrophic non‐as one of the fircines from fungalls are synthesame time I involutionary adapm currently evae brought newin more detail.
¥Equal contribuontribution rresponding au
¥Equal contribu
programa de es
extranjero 20
A. Ministerio d
n. May 2004
SECRETARÍA DEDE INVESTIGACDESARROLLO E
SECRETARÍA GEDE CIENCIA, TECE INNOVACIÓN
DIRECCIÓN GENDE INVESTIGACCIENTÍFICA Y TÉ
SUBDIRECCIÓN DE RECURSOS HPARA LA INVEST
organism to reecosystem, maht on the plan
dapted and adrst barriers of tgi origin. sized and remvestigate the tptation of the caluating the rolw areas of res.
ution
uthor
ution
stancias de mo
008�. Fundac
de Ciencia y Te
E ESTADO IÓN INNOVACIÓN
ENERAL CNOLOGÍA
NERAL IÓN
ÉCNICA
GENERAL HUMANOS TIGACIÓN
espond to stressany of which arent cell biology
apted fungi. Amhe plant cell ag
odelled. One orafficking pathcanonical eukare of this procesearch into the
vilidad postdoc
ión Alfonso M
cnología. Spain
s and e still : the
mong gainst
of my ways ryotic ss on e lab
ctoral
Martín
n. Jan
‐ P‐ R‐ AM‐ A PR‐ S‐ M‐ 2‐ 2‐ J‐ 2 ED‐ P‐ D
MDY
PhD FellowshipResearch StudeAcademic Awaray 2002 Academic Awar
ROFESSIONAL ESince 2008: PosMar 2013: Visit2007‐2008: Pos2003‐2007: PhDul‐Oct 2006: Vi2002‐2003: Res
DUCATION PhD at UniversiDegree in Agric
MINISTERIO
E ECONOMÍACOMPETITIV
. Ministerio de ent Collaboratorrd:best academ
rd: the best aca
EXPERIENCE stdoc. Max‐Planing scientist. Castdoc.UPM, MaD student. UPMisiting scientist.search collabora
dad Politécnicaultural Enginee
A VIDAD
Ciencia y Tecnor Fellowship. U
mic national rec
ademic faculty r
nck Institute forarnegie Institutdrid, Spain. Pla
M,Madrid,Spain..Carnegie Institator. UPM,Mad
a de Madrid (UPering at UPM,M
AYUDASCONVO
ología, Spain. Mniversidad Politord. Instituto d
record. Fundaci
r Molecular Plaion. Departmenant innate imm. Plant innate itution. Departmdrid,Spain. Plan
PM), Madrid,Spadrid,Spain. Se
S RAMÓN YOCATORIA
May 2004 técnica de Madde la Ingeniería
ión General de
nt Physiology, Gnt of Plant Biolounity lab mmunity lab ment of Plant Bint innate immu
pain. Dec 2007.ep 2003; Sobre
Y CAJAL A 2013
drid, Spain. Sep a de España an
la Universidad
Golm‐Potsdamogy,Stanford, U
iology,Stanfordnity lab
Sobresaliente saliente cum la
SDD
SDE
DDC
SDP
2002 d Asociación M
Politécnica de
, Germany. PlaUSA. Plant cell b
,USA. Plant‐pat
cum laude aude
SECRETARÍA DEDE INVESTIGACDESARROLLO E
SECRETARÍA GEDE CIENCIA, TECE INNOVACIÓN
DIRECCIÓN GENDE INVESTIGACCIENTÍFICA Y TÉ
SUBDIRECCIÓN DE RECURSOS HPARA LA INVEST
Mutualista de In
Madrid, Spain.
nt Cell Walls labiology lab
thogen interact
E ESTADO IÓN INNOVACIÓN
ENERAL CNOLOGÍA
NERAL IÓN
ÉCNICA
GENERAL HUMANOS TIGACIÓN
ngeniería Civil,S
Jan 2002
b
tion lab
Spain.
NoReÁreCo TítVi
ReI aKi(in1. stanre2.
stareprba3. gr(2thnostintM
memNaNa
paou
RePU1. 2. 3. 4. 5. 6. 7. 8. 9. 1011121314
MDY
ombre: ferencia: ea Científicaorreo Electró
tulo: ral DNA replica
sumen de laam a PhD reseangdom. I havencluding Nat RePhD training. udies. From thand The Journal elated DNA‐bindInternational s
ay in the Jeffereported for the romote efficienacteria. Postdoctoral p
roup (CBMSO). 012). These pae bacterial nucovel gene delivudents that arteraction betwolecular Micro
In 2011, I oain research pmbryonic develature, Cell, Natature Reviews M My long‐te
athological disoutstanding rese
sumen del CUBLICATIONS Authorship: FirAuthorship: FirAuthorship: SeAuthorship: SeAuthorship: SeAuthorship: SeAuthorship: CoAuthorship: CoAuthorship: Fir0. Authorship: F1. Authorship: F2. Authorship: F3. Authorship: S4. Authorship: S
MINISTERIO
E ECONOMÍACOMPETITIV
MUÑOZ RYC‐2013
a: Biología Fnico: dmu
tion ‐ Cellular S
a Memoria: archer with ovee published sixev Mol Cell BiolMy doctoral that period (2002of Biological Chding protein thastay. In 2005, I
y Errington�s first time that,
nt viral DNA rep
period. I did a From this stagpers describe tcleoid and, unevery system thare defending thween viruses anbiology (2013),
btained a �Juaproject in Cell lopment. The sture Reviews MMolecular Cell rm goal is to f
orders, and I earch.
Currículum V
rst Author. Revrst Author. Jouenior and Correecond Author. Jenior and Correecond Author. Jo‐First Author. Jo‐Senior and Corst Author. RevFirst and CorresFirst Author. JoFirst Author. JoSecond Author.Second Author.
A VIDAD
ESPIN, DAN3‐14471 [email protected]
Senescence in D
er 10 years� exteen research ), experience dhesis was carri2 to 2006), I puhemistry (2004at organizes virmoved to the S
laboratory (me similar to somplication, and th
first postdoctoge, I would like that phage termexpectedly, a fuat has been liceheir doctoral thnd their hosts,, where I partic
an de la Cierva�(2013), which scientific commMolecular Cell BBiology, which urther characte
consider that
Vitae:
view: Nat Rev Mrnal: Cell (2013esponding AuthJournal: Mol Miesponding AuthJournal: CommuJournal: PNAS (orresponding Aview: Adv Virus sponding Authournal: PNAS (20urnal: J Biol Che Book Chapter: Journal: The E
AYUDASCONVO
NIEL
l y de Sistemes
Development
experience in tarticles (includirecting PhD stued out in Margblished a total , 2005 and 200ral DNA replicatSir William Dun
ember of the Rome eukaryotic vihis functional p
oral stay (from to highlight tw
minal proteins cunctional nucleensed to Sygnisheses in the fir, two papers wipate as senior
� contract to wdescribes for
munity has receBiology and EMis currently in perize and unde
a �Ramón y
Mol Cel Biol (2013). Impact Factoor. Journal: Moicrobiol (2013).or. Journal: PNun Integr Biol (2(2012). Impact uthor. Journal: Res (2012). Impor. Journal: PNA009). Impact Faem (2007). Imp: BacteriophageMBO Journal (2
S RAMÓN YOCATORIA
mas
the fields of DNding first authudents, and leagarita Salas' grof 7 articles, 4 07). My main dition in bacteriann School of Pa
oyal Society) I piruses, prokaryoproperty is wide
2007‐2011) wwo articles in PNcontain a DNA‐bear localizations AG Pharma. Mrst half of 201were additiona(or co‐senior) a
work in the grothe first time
eived this papeMBO Journal. Inpress (2014). erstand the role
y Cajal� contr
14). Impact Facor: 31.957 ol Microbiol (20. Impact FactorAS (2013). Imp2013). Impact FFactor: 9.681 PNAS (2012). Ipact Factor: 3.9AS (2010). Impaactor: 9.380 pact Factor: 5.5e (2007). Impac2006). Impact F
Y CAJAL A 2013
NA replication hor papers in Cadership potentoup, at the CBof them as firsiscovery during. athology (Unive
published an arotic viruses areespread in bact
orking in viroloNAS as a first abinding domain signal (NLS). BMoreover, I ha4 (one of themally published iand as correspo
oup of Dr. Manuthat cellular sr enthusiasticaaddition, we h
e of cellular se
ract would pro
ctor: 37.162
013). Impact Fa: 4.961 act Factor: 9.73Factor: ‐
mpact Factor: 9971 act Factor: 9.77
81 ct Factor: ‐ Factor: 10.086
SDD
SDE
DDC
SDP
and Cell BiologCell, PNAS, EMtial. BMSO, and wasst (or co‐first) ag this period wa
ersity of Oxford
rticle in PNAS as able to exploiteriophages infe
ogy and bacterauthor (2010 ann to attach the vBased on this wve co‐directed m on February in PNAS (2012onding author.
uel Serrano, at tsenescence prolly and it has bhave written a
nescence durin
ovide the nece
ctor: 4.961
37
9.681
1
SECRETARÍA DEDE INVESTIGACDESARROLLO E
SECRETARÍA GEDE CIENCIA, TECE INNOVACIÓN
DIRECCIÓN GENDE INVESTIGACCIENTÍFICA Y TÉ
SUBDIRECCIÓN DE RECURSOS HPARA LA INVEST
gy trained in SpMBO J, and JBC
s focused on vauthor in The Eas a bacterioph
d) as a final PhD
s first author (2t the cytoskeletecting gram‐po
rial cell biologynd 2012) and aviral DNA repliwork, we develthe research p28th). From t
2 and 2013), a
the CNIO. Receomotes tissue been the topic review coverin
ng embryonic d
essary continu
E ESTADO IÓN INNOVACIÓN
ENERAL CNOLOGÍA
NERAL IÓN
ÉCNICA
GENERAL HUMANOS TIGACIÓN
pain and the UC) and two rev
iral DNA replicMBO Journal (2hage homeodom
D training. From
2009). In this wton of their hosositive and ‐neg
at Margarita Sa review manuscation machineoped a patent projects of twohis research onnd an extra on
ently, I publisheremodelling dof commentaring this novel fie
development a
ity to develop
nited views
ation 2003) main‐
m this
work, I sts to gative
Salas' script ery to on a
o PhD n the ne in
ed my uring ies in eld in
nd in
p this
1516171819 DOPhTitRe PhTitEs PAPaApTitLicPC INCeCiPe FE202020I h COI h AC2020 HO2020
MDY
5. Authorship: S6. Authorship: C7. Authorship: S8. Authorship: F9. Authorship: C
OCTORAL THEShD Student: Davtle: Estudios fueading Date: Fe
hD Student: Isatle: Estudios fustimated Readin
ATENTS atent presentedpplication Numtle: Utilización censed: Sygnis CT stage: PCT/E
NTERNATIONAL entre: Sir Williaty, Country: Oxeriod: 7 months
ELLOWSHIPS AN002‐2006. Fello007‐2010. I3P c011‐Present. 'Juhave participate
ONFERENCES have participate
CCREDITATIONS010. Accreditati012. Certificate
ONOURS AND A006‐2007. PINP006‐2007. Spec
MINISTERIO
E ECONOMÍACOMPETITIV
Second Author.Co‐First AuthorSecond Author.First Author. JoCo‐First Author
ES vid Ballesteros ncionales de laebruary 28th, 20
bel Holguera Áncionales de lang Date: June, 2
d at the 'Oficinaber: P2023110de Señales de LAG Pharma (20ES2013/070498
STAYS m Dunn Schooxford, UK s, from 20th Fe
ND PROJECTS w of the Fund fontract of the 'uan de la Ciervaed as a Collabo
ed as a speaker
S ion for Assistanof Competency
AWARDS prize to the beial doctorate aw
A VIDAD
Journal: J Biol . Journal: J Biol Journal: J Neuurnal: J Biol Che. Journal: The E
Plaza. proteína p1 y d014.
lvarez. proteína p6 y d2014.
a Española de P7 Localización Nu013).
l of Pathology,
bruary 2005 to
for Health Rese'Consejo Supera' contract of thrator Researche
r, with a poster
nt Professor by y on Laboratory
est doctoral theward in biology
AYUDASCONVO
Chem (2005). IChem (2005). rooncol (2004)em (2004). ImpEMBO Journal (2
de la proteína p
de proteína ter
Patentes y Marc
uclear de Proteí
University of O
20th Septemb
earch (FIS), ISCIior de Investigahe 'Spanish Miner in 19 project
presentation o
ANECA. y Animal Scienc
esis performed y of the 'UAM'.
S RAMÓN YOCATORIA
mpact Factor: 5Impact Factor: . Impact Factorpact Factor: 6.32003). Impact F
p17 del bacterió
rminal del bacte
cas' (2012).
ína de Bacterióf
Oxford
ber 2005.
II. aciones Científicnistry of Sciencets by national a
or as a co‐autho
ces for Researc
in the 'CBMSO'
Y CAJAL A 2013
5.854 5.854 r: 1.968 55 Factor: 10.698
ófago phi29.
eriófago phi29.
fagos como Ve
cas' (C.S.I.C.) foe and Innovationd internationa
or in a total of 2
hers: Category
' and presented
SDD
SDE
DDC
SDP
hículos para Tra
or young PhD. on'. al funding bodi
25 congresses.
C.
d at the 'UAM'.
SECRETARÍA DEDE INVESTIGACDESARROLLO E
SECRETARÍA GEDE CIENCIA, TECE INNOVACIÓN
DIRECCIÓN GENDE INVESTIGACCIENTÍFICA Y TÉ
SUBDIRECCIÓN DE RECURSOS HPARA LA INVEST
ansferencia de
es.
E ESTADO IÓN INNOVACIÓN
ENERAL CNOLOGÍA
NERAL IÓN
ÉCNICA
GENERAL HUMANOS TIGACIÓN
Genes.
NoReÁreCo TítRosu
ReDunepugoac20SuprmUnstAsthStinvIndePa
Ac
Ac
COneweteHu
ReDunepugoac20SuprmUnstAsthStinvInde
MDY
ombre: ferencia: ea Científicaorreo Electró
tulo: ole of purinergibependymal zo
sumen de lauring my PhD ieuroprotection ublications (4 aovernmental inctivities of the d007‐2008 and 4ubsequently I mrogression of thurine subependniversität of Maudied in my hos a consequencem currently sem Cell (Co‐auvolved in 6 inteaddition I was
eveloped technasteur Institute
ccreditations (A
ccreditation an
ONTRATADO Detwork of worldere based on taching activitiumanmediziner
sumen del Curing my PhD ieuroprotection ublications (4 aovernmental inctivities of the d007‐2008 and 4ubsequently I mrogression of thurine subependniversität of Maudied in my hos a consequencem currently sem Cell (Co‐auvolved in 6 inteaddition I was
eveloped techn
MINISTERIO
E ECONOMÍACOMPETITIV
ORTEGARYC‐2013
a: Biología Fnico: felip
c signaling on none
a Memoria: n the laboratorexerted by nuas first author nstitutions and department of 45 hours of Phamoved to the lahe neural stem dymal zone unainz. In additiost laboratory. ce of our findinubmitted/in reuthor), Nature ernational projes selected as siques (includine of Athens in
ANECA) For the
nd Prospective
OCTOR� and dwide contactsthe results andes in the Ludr (7M0408) for
Currículum Vn the laboratorexerted by nuas first author nstitutions and department of 45 hours of Phamoved to the lahe neural stem dymal zone unainz. In additiost laboratory. ce of our findinubmitted/in reuthor), Nature ernational projes selected as siques (includin
A VIDAD
A DE LA O, F3‐13290 Fundamentapeortega80@
neuronal surviv
ry of Prof Mariucleotide recepand one as s one project fBiochemistry armacological Baboratory of Mcells and the mder the supervn I could also c
ngs, a total of 8vision) includinCell Biology (1ects funded by peaker and teag the LMU‐Harvn 2013). I also
title �PROFES
e of the Univ
�PROFESOR Ds that resulted d scientific toodwig Maximiliathe Medicine d
Vitae: ry of Prof Mariucleotide recepand one as s one project fBiochemistry armacological Baboratory of Mcells and the mder the supervn I could also c
ngs, a total of 8vision) includinCell Biology (1ects funded by peaker and teag the LMU‐Harv
AYUDASCONVO
ELIPE
l y de [email protected]
val/Study of the
a Teresa Mirastors on cerebesecond). In addfunded by theand Molecular iochemistry in 2agdalena Götz mechanisms regision of Prof Becontribute signi
8 publications wng highly prestigst and co‐corrthe German goacher to severavard young scie obtained the
SOR AYUDANTE
ersities of Ma
DE UNIVERSIDAin several inte
ols/protocols deans Universitädegree in the ac
a Teresa Mirastors on cerebesecond). In addfunded by theand Molecular iochemistry in 2agdalena Götz mechanisms regision of Prof Becontribute signi
8 publications wng highly prestigst and co‐corrthe German goacher to severavard young scie
S RAMÓN YOCATORIA
mas
e mechanisms r
s Portugal, I focellar granule nedition, I contrie Marcelino BoBiology IV at th2008). at the Ludwig gulating the neenedikt Berningficantly to the
were obtained gious Journals aresponding autovernment/Euroal internationaentists forum (2 Positive evalu
E DOCTOR� (F
adrid for the
AD PRIVADA�ernational collaeveloped durinät of Munich cademic years 2
s Portugal, I focellar granule nedition, I contrie Marcelino BoBiology IV at th2008). at the Ludwig gulating the neenedikt Berningficantly to the
were obtained gious Journals aresponding autovernment/Euroal internationaentists forum (2
Y CAJAL A 2013
regulating adult
cused on the steurons. As a rebuted to the otin Foundationhe University C
Maximilians Unurogenesis andger, with whomfield of cellular
(4 of them as as Developmenthor) and Cell (opean Agenciesal meetings and2011) and the Ruation of the
February 2012)
title of �PRO
(August 2012borations withng my postdoc(150 hours in2009‐2012).
cused on the steurons. As a rebuted to the otin Foundationhe University C
Maximilians Unurogenesis andger, with whomfield of cellular
(4 of them as as Developmenthor) and Cell (opean Agenciesal meetings and2011) and the R
SDD
SDE
DDC
SDP
t neurogenesis
tudy of the signsult of my PhDdevelopment on. Moreover I omplutense of
niversität of Md oligodendrogem I moved afterr reprogrammin
first author, 2 nt (1st author), (second authors (5 as a collabod courses in orRIIP InternationNational Agen
and positive ev
OFESOR AYU¬
2). Furthermorrenowned lab
ctoral period. Ln the subject
tudy of the signsult of my PhDdevelopment on. Moreover I omplutense of
niversität of Md oligodendrogem I moved afterr reprogrammin
first author, 2 nt (1st author), (second authors (5 as a collabod courses in orRIIP Internation
SECRETARÍA DEDE INVESTIGACDESARROLLO E
SECRETARÍA GEDE CIENCIA, TECE INNOVACIÓN
DIRECCIÓN GENDE INVESTIGACCIENTÍFICA Y TÉ
SUBDIRECCIÓN DE RECURSOS HPARA LA INVEST
and oligodend
naling pathwayD research I puof 7 research actively partic
f Madrid (80 ho
unich. There, I enesis that takerwards to the Jng, the other m
of them as a sNature Protocor, under revieworator and one rder to share rnal course (55 hncy for Evaluat
valuation of th
¬DANTE DOCTO
re, I could estaboratories. All tLikewise I also of Praktikum
naling pathwayD research I puof 7 research actively partic
f Madrid (80 ho
unich. There, I enesis that takerwards to the Jng, the other m
of them as a sNature Protocor, under revieworator and one rder to share rnal course (55 h
E ESTADO IÓN INNOVACIÓN
ENERAL CNOLOGÍA
NERAL IÓN
ÉCNICA
GENERAL HUMANOS TIGACIÓN
drogliogenesis i
ys activated andublished a totalprojects fundecipated in teacours Biochemist
studied the lines place in the ohannes Guten
main line of rese
second author ols (1st author)w). Moreover, as a co‐cordinaesults and ourhours) at the Hetion of Quality
e agency of Qu
OR�, �PROF
ablish a widespthese collaboracontributed to
m Physiologie
ys activated andublished a totalprojects fundecipated in teacours Biochemist
studied the lines place in the ohannes Guten
main line of rese
second author ols (1st author)w). Moreover, as a co‐cordinaesults and ourhours) at the He
n the
d the l of 7 ed by ching try in
neage adult nberg earch
(3 of ), Cell I was ator). r self‐elenic y and
uality,
ESOR
pread ations o the I für
d the l of 7 ed by ching try in
neage adult nberg earch
(3 of ), Cell I was ator). r self‐elenic
Pa
Ac
Ac
COneweteHu
MDY
asteur Institute
ccreditations (A
ccreditation an
ONTRATADO Detwork of worldere based on taching activitiumanmediziner
MINISTERIO
E ECONOMÍACOMPETITIV
e of Athens in
ANECA) For the
nd Prospective
OCTOR� and dwide contactsthe results andes in the Ludr (7M0408) for
A VIDAD
n 2013). I also
title �PROFES
e of the Univ
�PROFESOR Ds that resulted d scientific toodwig Maximiliathe Medicine d
AYUDASCONVO
obtained the
SOR AYUDANTE
ersities of Ma
DE UNIVERSIDAin several inte
ols/protocols deans Universitädegree in the ac
S RAMÓN YOCATORIA
Positive evalu
E DOCTOR� (F
adrid for the
AD PRIVADA�ernational collaeveloped durinät of Munich cademic years 2
Y CAJAL A 2013
uation of the
February 2012)
title of �PRO
(August 2012borations withng my postdoc(150 hours in2009‐2012).
SDD
SDE
DDC
SDP
National Agen
and positive ev
OFESOR AYU¬
2). Furthermorrenowned lab
ctoral period. Ln the subject
SECRETARÍA DEDE INVESTIGACDESARROLLO E
SECRETARÍA GEDE CIENCIA, TECE INNOVACIÓN
DIRECCIÓN GENDE INVESTIGACCIENTÍFICA Y TÉ
SUBDIRECCIÓN DE RECURSOS HPARA LA INVEST
ncy for Evaluat
valuation of th
¬DANTE DOCTO
re, I could estaboratories. All tLikewise I also of Praktikum
E ESTADO IÓN INNOVACIÓN
ENERAL CNOLOGÍA
NERAL IÓN
ÉCNICA
GENERAL HUMANOS TIGACIÓN
tion of Quality
e agency of Qu
OR�, �PROF
ablish a widespthese collaboracontributed to
m Physiologie
y and
uality,
ESOR
pread ations o the I für
NoReÁreCo TítEp
ReDu(NPole(M I tCodifspthsulaplidonancothce20I sPopr
RePuRein au Re‐ pr‐ 20‐ Pca‐ 20‐ E M
MDY
ombre: ferencia: ea Científicaorreo Electró
tulo: pigenetic events
sumen de lauring my PhD (Nucleosome Reolycomb Represukemogenesis,Morey et al. MC
then moved toopenhagen), wfferentiation. Ppecifically expree coding mRNAuggesting a newboratory, to duripotency andentity. I discovenly confers distnd differentiatioomplexes in ESCat PRC1 complertain genes, w013). strongly believeolycomb complrogression.
sumen del Cublications: I haeports, MCB anjournals like N
uthor of an artic
eseach experienStaff scientistresent
 Post‐doctoral r012
 Post‐doctoral rancer biology.&Pre‐doctoral re008
 Erasmus fellows
entoring: I hav
MINISTERIO
E ECONOMÍACOMPETITIV
MOREY RYC‐2013
a: Biología Fnico: lluis
s in cancer and
a Memoria: (2003‐2008) in modeling and ssive complex since depletioCB, 2008). There
Copenhagen awhere I becameProfound analyessed in pluripoA of these genw mechanism io my second d differentiatioered that the Pinct target seleon of ESCs (MoC. Canonical anexes containing
which confers sp
e that my studlexes in a broa
Currículum Vave published ad TiBS. MoreovNature, Molecucle published in
nce: t: Centre for
research: Centr
research: Biote
Supervisesearch: Centre
ship: Departme
e experience in
A VIDAD
RAMONELL3‐14098 Fundamentas.morey@crg
development
the laboratoryDeacetylase co2 (PRC2) and ton of several mefore, loss‐of fu
as a postdoctoe interested inysis of the pluotent ESC, but nes, bind to theinvolved in ESCpostdoc. I emon. I am payingRC1 complex activity of the Porey et al. Cell Snd non‐canonicg either Cbx7 opecific biologica
dies summarizeader direction,
Vitae: a total of 17 pever, I am secondular Cell, Cancen Cell Reports in
Genomic Regu
re for Genomic
ch Research ansor: Dr. Kristiane for Genomic
ent of Microbio
n supervising m
AYUDASCONVO
L, LLUIS
l y de Sistemg.eu
y of Luciano Di omplex) facilitahe DNA methymembers of thunction of the N
ral fellow in thn the epigeneturipotency locinot in differene active histoneC pluripotency barked on a bg particular attrchitecture is nRC1 complex dStem Cell, 2012cal PRC1 compleor RYBP have spal function, and
ed above opento better unde
eer‐reviewed ard author in sever Cell, EMBO Jn 2013.
ulation. Differe
c Regulation. D
nd Innovation Cn Helin. 2008‐20c Regulation. D
logy. Thesis Dir
aster and PhD
S RAMÓN YOCATORIA
mas
Croce (CRG, Baates the recruityltransferase DNhe NuRD compNuRD complex c
he laboratory otics mechanism, like Oct4 anntiated cells. Ine modification (manuscript u
broader directitention in charnot static, but rauring ESCs diffe2). Moreover, I exes are definepecific biologicad enzymatic ac
n new paths anerstand the fu
rticles in top‐tiveral papers, anJ and Genes a
entiation and
Differentiation
Center (Univer010
 Differentiation
rector: Dr. Jan T
students. I am
Y CAJAL A 2013
arcelona) I disctment to chromNMT3A. Importlex resulted incould be exploi
of Kristian Helinms that regulatd Nanog, reventerestingly, theH3K4me3, andnder preparation to understaracterizing the ather dynamic.erentiation, butdissected the fed by the preseal functions, thetivity, of these
nd questions thnction of these
er journals. As d I have been and Developme
Cancer Progr
and Cancer Pr
rsity of Copenh
and Cancer Pr
Tommassen. Ut
currently co‐su
SDD
SDE
DDC
SDP
covered that in matin of two oftantly, this epig spontaneous ted for therape
n (Centre for Ete embryonic ealed that longese ncRNAs ared their depletioon). In 2010 mand the epigenfunction of thImportantly, tht also achieves function of the ence of either Ceir genomic loctwo PRC1 com
hat prompted e complexes in
first author I pactively involvent (see CV for
ram. Superviso
rogram. Superv
hagen). Gene R
ogram. Superv
trecht Universit
upervising a doc
SECRETARÍA DEDE INVESTIGACDESARROLLO E
SECRETARÍA GEDE CIENCIA, TECE INNOVACIÓN
DIRECCIÓN GENDE INVESTIGACCIENTÍFICA Y TÉ
SUBDIRECCIÓN DE RECURSOS HPARA LA INVEST
leukemic cellsf the main epigenetic mechandifferentiationeutic interventi
pigenetics andstem cell (ESCg non‐coding e nuclear, expron resulted in lmoved back to netic mechanise canonical PRhis subunit comthe balance becanonical and Cbx or RYBP pocalization it is mmplexes (Morey
me to investign development,
published in Ceed in studies, whr details). I am
or: Dr. Luciano
visor: Dr. Lucia
Regulation, Epig
visor: Dr. Lucia
teit. 2002‐2003
ctoral thesis.
E ESTADO IÓN INNOVACIÓN
ENERAL CNOLOGÍA
NERAL IÓN
ÉCNICA
GENERAL HUMANOS TIGACIÓN
s the NuRD comgenetic factorsnism is essentia of leukemic bion.
BRIC, UniversiC) pluripotencyRNAs (ncRNAsressed anti‐senloss of ESC ideLuciano Di Crosm involved inRC1 complex inmposition switcetween pluripotnon‐canonical olypeptides. I fmutually exclusiy et al. Cell Rep
gate the functio, but also in ca
ell Stem Cell (2)hich were publialso correspon
o Di Croce. 2
ano Di Croce. 2
genetics, stem
no Di Croce. 2
3..
mplex s, the al for blasts
ity of y and ) are se of ntity, oce¿s n ESC n ESC h not tency PRC1 found ive in ports,
on of ancer
), Cell ished nding
2012‐
2010‐
cells,
2003‐
Aw‐ P‐ P‐ P‐ P‐ P‐ EPaon
‐
dif
‐ I
pl‐ H
MDY
wards: Post‐doctoral fePost‐doctoral fePost‐doctoral fePost‐doctoral fePre‐doctoral felErasmus fellowsarticipation in cnes I was invite
IV CRG‐Postd
fferentiation?�MB Conferenc
uripotency andHerrenhausen S
MINISTERIO
E ECONOMÍACOMPETITIV
ellowship (4DCeellowship (Novaellowship (Beauellowship (Biotellowship (Centrship (Universitaconferences: I hd as a speaker.
oc symposium
�
e: Chromatin D
d differentiationSymposium on
A VIDAD
ellFate‐Funded artis‐CRG) 2010utriu de Pinós) 2ech Research aro de Regulacióat de Barcelonahave participat
m. 19th Novem
Dynamics & Ste
n�. Stem Cells and
AYUDASCONVO
by the Europea0 2010 nd Innovation Cn Genómica, Baa) 2002 ed in many nat
mber 2013. �
em Cells‐ 17th‐
Regenerative M
S RAMÓN YOCATORIA
an Commission
Center, Universarcelona) 2003
tional and inte
�What are th
‐20th October 2
Medicine ‐ Octo
Y CAJAL A 2013
n 2012 FP7)
sity of Copenha
rnational meet
he molecular
2013. �Role o
ober 8‐10, 2013
SDD
SDE
DDC
SDP
8232;
agen) 2008
tings (see CV fo
mechanisms t
f different PRC
3 Hanover Germ
SECRETARÍA DEDE INVESTIGACDESARROLLO E
SECRETARÍA GEDE CIENCIA, TECE INNOVACIÓN
DIRECCIÓN GENDE INVESTIGACCIENTÍFICA Y TÉ
SUBDIRECCIÓN DE RECURSOS HPARA LA INVEST
or details); here
that drive em
C1 complex sub
many. Invited d
E ESTADO IÓN INNOVACIÓN
ENERAL CNOLOGÍA
NERAL IÓN
ÉCNICA
GENERAL HUMANOS TIGACIÓN
e I just mentio
mbryonic stem
bunits in mouse
delegate.
n the
cell
e ESC
NoReÁreCo TítAb
ReDuinfintfa AsimdecoreBesimpaAfgede12 Duthmmha
reIn‐Im‐G‐M Mspan
ReI ogr I cMto‐TroTh20‐T12
MDY
ombre: ferencia: ea Científicaorreo Electró
tulo: biotic stress tole
sumen de lauring my scienformation is trteraction: (1) Tctors (TFs) invo
s a doctoral stumpaired develoemonstrate thaomposition andegulated stomaehav, 4(9):873‐8milarities but aathway in plantfter my PhD, I wene family. Thievelopment, su266).
uring the postdat controls florainly on underechanism of reas been recentl
eviewed in a Sciaddition, I estammink*, Posé*Galvao et al. 201Moyroud et al. 2
y current interepecies such as snd the determin
sumen del Cobtained a degranted a Collabo
completed my iguel A. Botella
olerance. Particuhe DRY2 gene,oot developmenhe study of a dr013; Plant Cell, he TTL genes, 266).
MINISTERIO
E ECONOMÍACOMPETITIV
POSE PARYC‐2013
a: Biología Fnico: dpo
erance and flor
a Memoria: tific career myranslated into dThe identificatiolved in the reg
dent at the Unpment under at the gene wad drought tolerta opening/clo874). I also genlso important mts, yeast and anwas involved in is work revealeuch as male ga
doctoral periodral transition anrstanding the megulation basedy published in
ence �Perspeablished severa et al. 2012; Pla12; Plant J, 71(32011; Plant Cell
est is to translastrawberry. In pnation of the re
Currículum Vgree in Biology oration Fellows
PhD in the Depa and Victorianoularly I studied which links stent and drought ry2 suppressor 25(2):728‐743)which are invo
A VIDAD
ADILLA, DAV3‐12699 [email protected]
ral transition an
y research has developmental ion and characgulation of the f
iversity of Máladrought stressas involved in rance through osure and root nerated secondmechanistic diffnimals (Doblas ethe molecular ed that TTL gemetophyte dev
d I spent at thend flower devemolecular mechd in two functioNature (Posé e
ctive� article (al collaborationant Phys, 160(13):517‐526. l, 23(4):1293‐13
ate the expertisparticular, I amegulatory netwo
Vitae: from the Univeship for lab trai
partment of Bioo Valpuesta. I fthe following Aerol biosynthestolerance (Posidentified a po). olved in osmot
AYUDASCONVO
VID
l y de Sistem
nd developmen
been focused outcomes. Par
cterization of gfloral transition
aga I worked ons. As part of msterol biosynththe regulation development ‐site suppressoferences amonet al. 2013; Plancharacterizatioenes are specivelopment, and
e Max Planck Inlopment in Arahanisms by whnally antagoniset al. 2013; 503
(Nilsson 2013; 3s during this pe):433‐449 (*Eq
306.
se gained on them working on thorks controlled
ersity of Málagning during my
ología Moleculocused on the Arabidopsis gensis and the gensé et al. 2009; Positive regulato
tic stress tolera
S RAMÓN YOCATORIA
mas
nt in Arabidopsi
on understanrticularly, I havgenes involved n and fruit ripen
n the identificamy PhD thesis, hesis. This worof the produc(Posé et al. 20ors mutations og components nt Cell, 25(2):72on of Arabidopsific for land pld in abiotic str
nstitute (Tübinbidopsis. In pahich temperatustic splice varia(7476):414‐417
342(6158):566‐eriod that led toual contributio
e analysis of TFhe identificatio by these TFs.
ga (UMA) in Auy final year of th
ar y Bioquímicphysiological anes: eration of reacPlant J, 59(1):63or of HMGR act
ance and male
Y CAJAL A 2013
s
ding how planve focused on tin abiotic stre
ning.
ation and charaI isolated a drked revealed ction of reactiv009; Plant J, 59of dry2. Charactinvolved in the28‐743). sis mutants of tlants and play ress tolerance
gen, Germany)rticular I studiere regulates flonts of the MAD7) and Science (
‐567). o the publicatioon).
Fs in Arabidopsin of key TFs inv
gust 2003. Duehe Degree and a
a at the UMA nd molecular c
ctive oxygen sp3‐76) (Posé andivity, the key e
sporogenesis
SDD
SDE
DDC
SDP
ts perceive entwo important ess tolerance, a
cterization of Arought hypersan unexpectedve oxygen spec9(1):63‐76) (Poterization of one regulation of t
the TETRATRICOa regulatory r(Lakhssassi et a
), I investigateded the role of keowering time. IDS‐Box TF FLOW(Lee et al. 2013
on of the follow
is to understanvolved in the c
e to my high ma predoctoral fe
in October 200haracterization
ecies, which ind Botella 2009; nzyme of the m
(Lakhssassi et a
SECRETARÍA DEDE INVESTIGACDESARROLLO E
SECRETARÍA GEDE CIENCIA, TECE INNOVACIÓN
DIRECCIÓN GENDE INVESTIGACCIENTÍFICA Y TÉ
SUBDIRECCIÓN DE RECURSOS HPARA LA INVEST
nvironmental siaspects of theand (2) the stu
Arabidopsis muensitive mutand connection bcies (ROS). Theosé and Botellane of these suppthe key enzyme
OPEPTIDE THIOrole in differeal. 2012; Plant
d the complex ey TFs in these In this study, wWERING LOCUS 3; 342(6158):62
wing articles:
d developmentcontrol of straw
marks as undergellowship (FPU
08, under the sn of genes invol
n turn controls Plant Signal Bemevalonate pat
al. 2012; Plant
E ESTADO IÓN INNOVACIÓN
ENERAL CNOLOGÍA
NERAL IÓN
ÉCNICA
GENERAL HUMANOS TIGACIÓN
gnals and howe plant‐environudy of transcri
tants that dispnt (dry2) and cbetween root s production ofa 2009; Plant Spressors highlige of the mevalo
OREDOXIN‐LIKE nt aspects of Phys, 158(3):1
regulatory netprocesses, focwe identified aM (FLM). This
28‐632), which
tal programs inwberry fruit ripe
graduate (2,9) ).
supervision of Pved in abiotic s
stomata regulaehav, 4(9):873‐thway (Doblas
Phys, 158(3):1
w this ment ption
layed could sterol f ROS Signal ghted onate
(TTL) plant 1252‐
twork using new work were
crop ening
I was
Profs. stress
ation, 874). et al.
1252‐
Duth Afthtrafivm34TFal Inmid Duth(2thcu
MDY
uring my predoe supervision o
fter obtaining me Max Planck Ianscription factve peer‐revieweost important 42(6158):628‐6Fs. I also charac. 2012; Plant Ph
May 2013 I molecular backgrentification and
uring my scientan 30 national ) MPI and Unive UMA and Unurrently supervi
MINISTERIO
E ECONOMÍACOMPETITIV
octoral period I of Prof. Liam Do
my PhD, I workenstitute (MPI) tors (TFs) involed research artjournals of m32). These papcterized the rolehys, 160(1):433
moved to the IHround and techd analyses of TF
tific career I haand internatio
versity of Tübinniversidad Inteising a master t
A VIDAD
spent 4 montholan, where I ga
ed as a postdo(Tübingen, Gerlved in the regticles and a revultidisciplinary pers report the e of the TF SOC3‐449. *Equal co
HSM‐UMA‐CSIChnical skills learFs involved in s
ave participatedonal conferencegen (20 hours)rnacional de Athesis student.
AYUDASCONVO
s at the Cell anained experienc
ctoral researchrmany), from Seulation of floraview. Of particuscience, i.e. Ntemperature‐d
C1 in flowering ontributors).
C, funded by a ned using Arabtrawberry fruit
d in several intes. I have been . I have been andalucía in 201
S RAMÓN YOCATORIA
d Developmence in cell biolog
her in the groupeptember 2009al transition anular importanceNature (Posé edependent regby the identific
JAE‐DOC postdbidopsis to a crot ripening.
ternational andinvolved in theappointed as a 14. I have also
Y CAJAL A 2013
tal Biology Depgy and confocal
p of Dr. Markus9 until May 201d flower develoe are the followet al. 2013; 50ulation of flowcation of its up
doctoral fellowsop species such
d national I+D pe teaching of seprofessor in thsupervised sev
SDD
SDE
DDC
SDP
partment, John microscopy tec
s Schmid at the13. During this popment. This wwing publication3(7476):414‐41ering, focusing‐ and downstre
ship. I am currh as strawberry
projects, and I everal practical e Master de Bioveral undergrad
SECRETARÍA DEDE INVESTIGACDESARROLLO E
SECRETARÍA GEDE CIENCIA, TECE INNOVACIÓN
DIRECCIÓN GENDE INVESTIGACCIENTÍFICA Y TÉ
SUBDIRECCIÓN DE RECURSOS HPARA LA INVEST
Innes Centre (Nchniques.
e Molecular Bioperiod I focusework resulted ins, that include17) and Sciencg on the role ofeam regulators
rently interestey. In particular,
have presente courses: (1) Uotecnología Avduate and PhD
E ESTADO IÓN INNOVACIÓN
ENERAL CNOLOGÍA
NERAL IÓN
ÉCNICA
GENERAL HUMANOS TIGACIÓN
Norwich, UK), u
ology Departmeed on the analyn the publicatioe reports in thece (Lee et al. 2f several MADS(Immink*, Pos
ed in translatingI am working o
ed my work in mMA (120 hoursvanzada provideD students and
under
ent of sis of on of e two 2013; S‐Box é* et
g the n the
more ) and ed by I am
NoReÁreCo TítHo
ReMforoprpotracoexDubehiofdeThprtuhatu Re
ReAf
debiga
I jEdpure50
FotracapuI rwin Duincoep
coThsc
MDY
ombre: ferencia: ea Científicaorreo Electró
tulo: ox mediated co
sumen de lay research car
ocusing on the rostro‐caudally arecerebellar neools of RL proganscription facontrolling at thextrinsic mechanuring my postehaviour of RL stone methyl‐tf Hox paralog gerivative by chahe leading hyporogram implicatrn should direcave an anti‐tummors.
ecommended r
sumen del Cfter the two firs
e Paris�, a higology (first yeaave me a flavor
oined Dr Alain ducation Ministublished in 6 paesearch, I was a0 h /year).
ollowing this panscriptional coall. The bulk of mublished (J. Neurecently joinedithin her groupthis call and thuring my trainicluding immunollagen matrix pigenetic and tr
o‐author a bookhe additional sratch, defining
MINISTERIO
E ECONOMÍACOMPETITIV
DI MEGLRYC‐2013
a: Biología Fnico: thom
ontrol of neuron
a Memoria: reer has been frhombic lip (RLand tangentialurons. During mgenitors is maictors (TFs). Thee same time thnisms controls ndoctoral trainiderivatives byransferase at Lgroups (PG) 4 aanging their signothesis for my oting the TF Otxctly influence tmoral role in the
eference: Cons
Currículum Vst years at the P
ghly selective ar) and neuroscof different res
Chédotal�s later (three yearsapers (Plos Bioppointed as an
period I joined ontrol of neuromy postdoctorauroscience) whe the laboratoryp. During this pehat will give meng period I hadnohistochemistor organotypiranscriptional r
k chapter on �kills I acquiredg the hypothesi
A VIDAD
LIO MARTEL3‐14018 Fundamentamasdimeglio
nal diversity wit
focused in undL). The RL spanly migrating cmy thesis I workntained in the ese TFs in turnhe expression oneuronal migratng, we demony differentially ysine 27 (H3K2nd 5 of posternalling propertion‐going projecx2 could be reshe differential e different Otx
stantino Sotelo
Vitae: Paris VII Univer
and advanced ience (second ysearch topics. T
aboratory at thes) to undertakelogy, J. Neurosn Assistant Prof
Prof. F. Rijli�onal migration wal work has beeereas the othery of Prof. P. Boeriod I already the opportunitd the opportunry and in situ c cultures of tregulation appl
�Transcriptionad during my eigs and specific g
AYUDASCONVO
LLY, THOMA
l y de [email protected]
thin the rhomb
derstanding the the entire dorcell populationsked on the migmigrating pos
n confer the prof guidance motion along sterenstrated that Eregulating the 7me3) belongiior precerebellies. ct, based on strponsible of resresponse of RL2 or Shh depen
rsity studying ge
program compyear). During thThis convinced
e UMR7102 (Pa my Ph.D. The cience; Cerebeessor at the Un
�s lab at the with the suppoen recently pubr is in preparatiovolenta (CBMSaccumulated vty to begin my nity to acquire hybridization, athe brain, conied to neurona
l regulation of tght years of regoals, analysing
S RAMÓN YOCATORIA
AS
mas
bic lip lineage an
e molecular mersal hindbrain as, fated to beration of precest‐mitotic neurorecerebellar neolecules and theeotyped pathwEzh2 dependeexpression of ng to the Polycar RL precurso
rong preliminarstricting the latL derivatives tondent medullob
eneral cellular b
prehensive of bhis period, I hadme to pursue m
aris VI, France) outcome of mellar cortex) andniversity Paris V
FMI (Basel, Swort of an EMBO blished in Scienon. SO, Madrid), wvery encouraginindependent retechnical skillsaxon tracing (Dnfocal, bi‐photoal specification,
tangential neuresearch experieg the results w
Y CAJAL A 2013
nd its possible c
echanisms thatand is composeecome, within erebellar populaons by the comeurons with their receptors. Sway. nt epigenetic the Hox transccomb Repressivors. This restrict
ry results, is thate expression o Shh mitogenicblastomas that
biology, I enrol
biochemistry fod the opportunmy career in De
and soon aftery PhD researchd a review pubVI to teach Cellu
witzerland) andPostdoctoral Fce. I also co‐au
who gave me thng preliminary desearch carrier.s in embryologyDye and viral von and time‐la, migration and
ronal migrationences include twith a broad pe
SDD
SDE
DDC
SDP
consequences i
t orchestrate nd of precursor a defined seqation revealing mbinatorial expe appropriate Spatio‐tempora
regulation orccriptional codee Complex (PRCtion impacts on
at PRC2‐dependf Hox PG2 to pc activity. In thiare among the
l in the Master
ormation, a resnity of performivelopmental N
r was awarded h developed in tlished in a Frenular biology and
d I undertook Fellowships (twthored two oth
he opportunity data that are a. y applied to gevectors), in uteapse microscopd connectivity, w
� (Elsevier). the capacity ofrspective and u
SECRETARÍA DEDE INVESTIGACDESARROLLO E
SECRETARÍA GEDE CIENCIA, TECE INNOVACIÓN
DIRECCIÓN GENDE INVESTIGACCIENTÍFICA Y TÉ
SUBDIRECCIÓN DE RECURSOS HPARA LA INVEST
in medulloblast
neuronal migracells that give quence, cerebethat the spatiapression of speresponse to el integration of
chestrates the e. Indeed we sC) 2, restrict thn the migratory
dent regulationprecerebellar Ris context, Hox e most aggressi
of the �Ecole
search programing a rotation iNeurobiology.
with a Fellowsthree years andnch Journal. In d Genetic regul
a project on wo years) obtainher studies, one
y to lead my owt the basis of t
enetically enginero electroporapy. I also acquwhich gave me
f initiating reseundertaking re
E ESTADO IÓN INNOVACIÓN
ENERAL CNOLOGÍA
NERAL IÓN
ÉCNICA
GENERAL HUMANOS TIGACIÓN
toma formation
tion in vertebrraise to a streaellar, cochlear,l origin of restrecific classes ofenvironmental f these intrinsic
complex migrhowed that Eze spatial exprey behaviour of
n of a transcriptL. This regulatiPG2 activity shive types of juv
Nomale Supér
m in developmn different labs
hip from the Frd three monthsparallel, to myation (License
the epigeneticned in a compee of which is alr
wn research prhe project I pre
neered mouse ation, co‐culturuired knowledge the opportun
earch projects levant internat
n
rates, am of , and ricted f Hox cues, c and
atory h2, a ssion their
tional on in hould venile
ieure
ental s that
rench s was y PhD level,
c and titive ready
roject esent
lines, res in ge of ity to
from tional
coexamth
MDY
ollaborations wxperience in team a hard workine technical and
MINISTERIO
E ECONOMÍACOMPETITIV
when needed. Iaching to studeng person with d intellectual ex
A VIDAD
I also acquiredents at differena great enthusxpertise needed
AYUDASCONVO
written, editont levels (undersiasm, persuasivd to successfull
S RAMÓN YOCATORIA
orial and publicrgraduate to dve force and exy undertake th
Y CAJAL A 2013
c speaking skiloctorate) and pxcellent commue research prog
SDD
SDE
DDC
SDP
ls. This aspect presenting resuunication skills. gram presented
SECRETARÍA DEDE INVESTIGACDESARROLLO E
SECRETARÍA GEDE CIENCIA, TECE INNOVACIÓN
DIRECCIÓN GENDE INVESTIGACCIENTÍFICA Y TÉ
SUBDIRECCIÓN DE RECURSOS HPARA LA INVEST
t was particulaults at internat I therefore cond in this applica
E ESTADO IÓN INNOVACIÓN
ENERAL CNOLOGÍA
NERAL IÓN
ÉCNICA
GENERAL HUMANOS TIGACIÓN
rly favoured bional conferennsider that I haation.
y my ces. I ve all
NoReÁreCo TítRe
ReI pwamAfofpathdeprtraarAfjopethcothInmA RamacRethcoeu
ReI othMArTh20ThCecoUnprI pBiNoI hM
MDY
ombre: ferencia: ea Científicaorreo Electró
tulo: egulación del tr
sumen de lapursued my unas intern studeicrobiology. fter obtaining mf the Universityarticular the proat protein kinaepends on the troteins). My firsansport to ER.rchitecture. Wefter my thesis ined in 2006 theriod, I examinee transfer of promplex HOPS that the phosphothe next studembrane curvasecond focus oab GTPase conaturation: the ctivate Ypt7, theecently we idene HOPS subunonditions. Futurukaryotes.
sumen del Cobtained my Bie Spanish Mininistry of Educreces and Germhe results of my006; J Cell Sci 11he findings of mell Biol 191:845orresponding angermann 2013ress. published two ol. 10:759‐61, ordmann, Ungehad the opportuolecular Biolog
MINISTERIO
E ECONOMÍACOMPETITIV
CABRERARYC‐2013
a: Biología Fnico: mar
áfico intracelul
a Memoria: dergraduate stent in the Depa
my Biology degry of Seville. Duotein retrieval fase A (PKA) playtransport vesicst study showe My second we found that PKAdissertation anhe group of Pred the protein roteins and lipihat mediates thorylation of thedy we identifieature sensing anof my postdoc nversion from BLOC‐1 complee next Rab alonntified a novel cnit Vps39. There studies are n
Currículum Vology degree wnistry of Educatcation and Scieman Research foy PhD work are19:3764‐75 (*emy initial postd5‐59, Nordmanuthor: Cabrera3; J Biol Chem 2
article reviewsa methods reermann and Caunity to discussgy Organizatio
A VIDAD
A SOLA, MA3‐12858 Fundamentargarita.cabre
ar de proteínas
tudies (1994‐19rtment of Micr
ree in 1999, I jouring the PhD from the Golgi ys a crucial rolele coat (COPI) aed that the KDEwork was focusA is required fond my work as of. Christian Ucomplexes andds between orghe fusion of latee HOPS subunited a membrannd phosphorylawork was the tVps21‐ to Yptex required for ng the endocyticontact site bet assembly of necessary to re
Vitae: with special awation and Cultuence during myoundations. e included in twequal contributidoc research arn*, Cabrera* ea et al. 2013; J288:28704‐12.
s: Cabrera andview: Cabrera brera 2012; Bes my findings inn (EMBO), the
AYUDASCONVO
ARGARITA
l y de Sistemra@t‐online
s
999) in the Facuobiology, wher
oined the groupperiod my rescomplex and the in both proceand the KDEL reEL receptor is a sed in the assor maintaining tassistant profengermann in thd Rab GTPases ganelles. Using e endosomes wt Vps41 controlne curvature seation. transition fromt7‐positive endthe release of c pathway. tween mitochothis contact sieveal the entire
ard in 1999 (Fare during the y PhD period. M
wo publicationson). e part of threeet al. 2010; CurJ Biol Chem 28My last researc
Ungermann, 2and Ungermanntham e Booksn several meetie American So
S RAMÓN YOCATORIA
mas e.de
ulty of Biology,re I had the opp
p of Prof. Josefsearch was foche biogenesis oesses. The retroeceptor, which substrate of Pociation of PKthe characteristessor, I decidehe Departmentinvolved in meyeast as eukary
with the vacuolels its localizatioensor motif w
m early to late edosomes. Our f Vps21 from m
ondria and vacuite is controllee composition
aculty of Biologlast year of mMy postdoc res
s: Cabrera et al.
e articles: Cabrerr Biol 20:165488:5166‐75, Joch work has be
2010; Cell 141:nn 2008; Meths 10:132‐143. ngs organized bociety for Cell
Y CAJAL A 2013
, University of Sportunity to lea
ina Hidalgo andcused on the sof this organelleograde transporrecognizes the
PKA that requireKA with Golgi mtic Golgi structued to extend mt of Biochemistembrane tetheyotic model syse, the equivalenon to endosomeithin the phos
endosomes durfindings uncov
maturing endoso
uoles, which is med by phosphoand functions o
gy, University ofmy undergraduasearch was init
. 2003; Mol Bio
era et al. 2009;‐9 (*equal conhn Peter et aleen accepted fo
:404‐6 and Pephods Enzymol
by the EuropeaBiology (ASCB
SDD
SDE
DDC
SDP
Seville. During arn the basic te
d Angel Velascostudy of proteie. The results art between Gole escaped ER pres phosphorylamembranes anure and for its rmy knowledge itry, University ring and fusionstem I first studnt to the mammes and thereforsphorylation sit
ring endocytosivered two novomes and the M
mediated by thrylation of Vpof these memb
f Seville). I receate studies andtially supported
ol Cell 14: 4114‐
; Mol Biol Cell tribution). Last. 2013; J Cell or publication r
plowska, Cabre481:177‐96 an
an Life Science O) and the Fed
SECRETARÍA DEDE INVESTIGACDESARROLLO E
SECRETARÍA GEDE CIENCIA, TECE INNOVACIÓN
DIRECCIÓN GENDE INVESTIGACCIENTÍFICA Y TÉ
SUBDIRECCIÓN DE RECURSOS HPARA LA INVEST
the last two yeechniques in mo
o in the Departmin quality contssociated with lgi and endoplaroteins (chaperation for interacnd how this kireassembly upon the protein tof Osnabrück. n. These procesdied the regulatmalian lysosomre the timing ote of Vps41 lin
is. This processvel players invoMon1‐Ccz1 com
he Rab Ypt7 andps39 and depebrane contacts
eived a collabod a FPI fellowsd by two fellow
‐25 and Bejara
20:1937‐48, Cat year I publishBiol 201:97‐11recently: Cabre
ra and Ungermnd a book chap
Organization (Ederation of Eur
E ESTADO IÓN INNOVACIÓN
ENERAL CNOLOGÍA
NERAL IÓN
ÉCNICA
GENERAL HUMANOS TIGACIÓN
ears of my studolecular biology
ment of Cell Biotrol mechanismthis study indicasmic reticulumrones and misfoction with COPnase controls on Golgi disrupttrafficking fieldDuring my possses are essenttion of the teth
me. My work shof membrane funking for first
s is triggered bolved in endosmplex that is ab
d its binding pands on the grin yeast and h
ration fellowshship by the Spwships from Ra
no*, Cabrera*
abrera et al. 20hed three articl11 and Cabrerara et al. J Cell S
mann 2008; Natpter as last au
ELSO), the Euroropean Bioche
dies, I y and
ology ms, in cated m (ER) olded I and Golgi tion. d and stdoc tial in ering owed usion. time
y the some ble to
rtner owth igher
hip by anish amon
et al.
010; J es as a and Sci, in
t Cell uthor:
opean mical
SoDuwoprMprcoint
MDY
ocieties (FEBS) auring my PhD inorked as assistractical, two Bay publications wrogram provideollaboration betterest in the as
MINISTERIO
E ECONOMÍACOMPETITIV
among others. n the Departmetant professor. chelor and threwere crucial foed 8,5 million etween groups ossembly and fun
A VIDAD
ent of Cell BioloDuring my Po
ee Master studr obtaining a sieuro funding foof different discnctions of prote
AYUDASCONVO
ogy of the Univostdoc in the Dents in their engnificant suppoor 15 research ciplines (genetieins and lipids m
S RAMÓN YOCATORIA
versity of SevilleDepartment of nd of course proort from the Cogroups at the ics, biophysics, microcompartm
Y CAJAL A 2013
e I supervised pBiochemistry oojects. ollaborative ResUniversity of Ocell biology) an
ments.
SDD
SDE
DDC
SDP
practical courseof the Universi
search Center (Osnabrück and nd faculties (Ph
SECRETARÍA DEDE INVESTIGACDESARROLLO E
SECRETARÍA GEDE CIENCIA, TECE INNOVACIÓN
DIRECCIÓN GENDE INVESTIGACCIENTÍFICA Y TÉ
SUBDIRECCIÓN DE RECURSOS HPARA LA INVEST
es and after my ity of Osnabrüc
(SFB 944) that sMünster. This
hysics and Biolo
E ESTADO IÓN INNOVACIÓN
ENERAL CNOLOGÍA
NERAL IÓN
ÉCNICA
GENERAL HUMANOS TIGACIÓN
thesis dissertack I supervised
started in 2011action enabled
ogy) with a com
tion I d two
. This d the mmon
NoReÁreCo TítHe
ReDureprwdechcocotostorGaan
traerplfuplmsupa
RePo1 J2 3 4 5 6 7 Th Pu1 Pain 2 Ku3 Phpr4 p4
MDY
ombre: ferencia: ea Científicaorreo Electró
tulo: ematopoietic lin
sumen de lauring my PhD pegulation. I wasroject, which with Anna Rita epending on theharacterized theoupled to in vivollaborations wo a very importudies that confrchestrated proaljart, we definnd my own obs
afficking. I haverythropoietic datelets group. nction of plateatelets in tranegakaryopoiesiubmitted for puathophysiology
sumen del Cositions: Junior group lePostdoc, ErasmPhD student, EMaster studentPhD student, FaMaster studentPredoctoral stu
hesis defence: 2
ublications: Sabrina Zeddieathogen reductpress. 2014. I.M. De Cuypeuijpers; A.J. VerS. Bergink; A. Thilipsen; W. Veroteasome shutR. Fujita; M. Ta45 Is Important
MINISTERIO
E ECONOMÍACOMPETITIV
GUTIERRRYC‐2013
a: Biología Fnico: l.gut
neage different
a Memoria: period at the Ers then focused was awarded witMigliaccio thate DC subtype/me Gata1 and Po loss of functiith a number otant study that firmed anotherotein degradated the requireservations I hav
e contributed tefect in CD70TSince 2010 we
elets using verynsgenic mice is (mouse and ublication or in of platelet tran
Currículum V
ader, Sanquin RmusMC, RotterdrasmusMC, Rott, ErasmusMC, aculty of Biologt, Asturias Tranudent, Faculty o
29th June 2005
es; Iris M. De Cion treatment u
r; M. Meindersrhoeven; T.K. vaTheil; W. Toussrmeulen; J. Mitttling factor Radkayama‐Tsujim for Establishin
A VIDAD
REZ GUTIER3‐12587 Fundamentatierrez@me.
tiation in health
asmusMC I devon Gata1 functh a VENI grantt the transcriptmaturation stagU1 interactomeon studies, maf researchers, widentified KLF
r potential reguion during eryment of CLASPve started a ne
to the study oTg mice, a moe have developy low numbers aand patients. human) and thpreparation. I ansfusion.
Vitae:
Research, Amstdam ‐ 2005‐201tterdam ‐ 2000Rotterdam ‐ 20gy, Oviedo ‐ 199nsfusion Centre of Biology, Ovie
Cuyper; Pieter Fusing riboflavin
s; E. van de Vijan den Berg; L. saint; T. Clapestchell; L. Gutiéd23b. Mol Cell moto; H. Satoh; g Normal Funct
AYUDASCONVO
RREZ, LAURA
l y de Sistem.com
h and disease.
veloped interesction on erythrt. In particular, tion of Gata1 ge. We have idee and transcripterial that is bewho contacted 1 as a regulatoulator, which isthroid differen2 for HSC homiew project in w
riginated in Druse model of ped a novel flowand in a receptWe have buihese resourcesam currently in
terdam ‐ since 20. ‐2005. 000, 6 months.98, 1 year, not f(Centro Comun
edo ‐ 1997, 9 m
F. van der Meen and ultraviole
jver; D. de KorGutiérrez. A nos; R. van der Lirrez. ErythropoBiol. 2013. L. Gutiérrez; H.tion of Platelets
S RAMÓN YOCATORIA
A
mas
st on hematoporoid and dendrafter describinin DC is regulaentified interleuptome by usingeing prepared fme for my expor of haemoglos being preparentiation (W. Veing, turnover awhich we study
. Nolte�s lab, chronic sterilew cytometry btor‐wise manneilt in our lab s allow us to ennterested on me
2010.
finished. nitario de Transonths ‐ part tim
er; Brunette B. et light impairs p
rte; L. Porcelijnovel flow cytominden; J.A. Demoietic defect as
. Aburatani; S. Fs. Mol Cell Biol
Y CAJAL A 2013
oietic lineage diritic cells (DC), ng that Gata1 isated by differeukins that affecg mass spectrofor submission.pertise on erythobin switching (ed for submissiermeulen, J. Mnd commitmenthe CLASP2‐de
where we have inflammationbased platelet aer, which has bexpertise on
ngage into newegakaryopoiesi
sfusion del Prinme.
Daal; Dirk de Kplatelet reactiv
; M. de Haas; metry‐based plammers; J.A. Masociated with r
Fujii; A. Sarai; E. 2013.
SDD
SDE
DDC
SDP
fferentiation wresearch that s expressed in Dent hypersensitct Gata1 expresmetry analysis,A number of pro/hematopoie(Prof. J. Philipson. Another stuitchell, S. Bergnt and differentependent mech
ve identified th. At Sanquin, Iaggregation tesbeen successfulthe character
w studies, a nus and platelet f
ncipado de Astu
Korte; Daphne ity towards spe
J.A. Eble; K. Setelet aggregatioarteijn; I.M. De reduced cell pro
E.H. Bresnick; M
SECRETARÍA DEDE INVESTIGACDESARROLLO E
SECRETARÍA GEDE CIENCIA, TECE INNOVACIÓN
DIRECCIÓN GENDE INVESTIGACCIENTÍFICA Y TÉ
SUBDIRECCIÓN DE RECURSOS HPARA LA INVEST
with an emphasgave rise to mDC, we discovetive sites at thssion in human , ChIPseq and projects arose aesis. Examples sen, Prof. G. Paudy highlightedgink). In collabtiation. Derivedhanisms of cKit
he transcriptionI am in chargest, that can bely applied to strisation of plamber of them function in hea
urias) ‐ 1998, 3
Thijssen‐Timmecific agonists i
eeger; S. Rutellon assay. Bloode Cuyper; T. vanroliferation in m
M. Yamamoto; H
E ESTADO IÓN INNOVACIÓN
ENERAL CNOLOGÍA
NERAL IÓN
ÉCNICA
GENERAL HUMANOS TIGACIÓN
is on transcriptmy first indepenred in collaborhe Gata1 promand mouse DCRNAseq technoas a result of frare my contribatrinos) and ded the importanoration with Dd from these stt and cMpl rece
nal axis leadinge of developing used to assestudy the functioatelet function are currently blth and disease
months.
er; Laura Gutién vitro. Transfu
la; D. Pagliara; d. 2013. n Gent; C. Robmice lacking the
H. Motohashi. N
tional ndent ation
moter, C, and ology uitful ution erived ce of Dr. N. udies eptor
g to a g the s the on of and
being e, and
érrez. usion,
T.W.
in; S. e 26S
NF‐E2
5 Re6 Gl7 MItace8 IFBl9 JCaPhGe
MDY
P. Papadopouleporter Mouse E. van de Vijvlanzmann thromL. Gutiérrez; K.. van den Houtaliano Jr; C. Roell maintenanceL. Gutiérrez; SNgamma produood. 2011. J. Borg; P. Papaassar; R. Galdiehilipsen. Haploenetics. 2010.
MINISTERIO
E ECONOMÍACOMPETITIV
los; L. GutiérreModel of the Hver; I.M. De Cumbasthenia and Drabek; M. Vet; M. Meindersbin; N. Galjart.e. Cell Reports. .F. Libregts; A.uction in mice
adopoulos; M. Ges; W. van IJckeoinsufficiency fo
A VIDAD
ez; R. van der Human b‐Globinuyper; A.J. Gerd LAD‐III (LAD‐1ermeij; T. Clapes; C. Melo; C. S The microtubu2012. M. de Bruin; Finduces anem
Georgitsi; L. Guen; Z. Ozgür; Nor the erythro
AYUDASCONVO
Linden; J. Kongn Locus: Applicarrits; A.J. Verho1/v) syndrome: es; S.R. Patel; J.CSambade; D. Drule plus‐end tra
.M. Wensveenia by reducing
utiérrez; G. GrecN. Gillemans; J.oid transcriptio
S RAMÓN YOCATORIA
g‐A‐San; A. Maations and Limioeven; K. Seeg the role of inteC. Boisset; J. varabek; R.W. Heacking protein
; P. Papadopouerythrocyte lif
ch; P. Fanis; M. Hou; M. Bugeon factor KLF1
Y CAJAL A 2013
aas; D. Drabek;itations. Plos Oger; L. Gutiérreegrin b1 and b3an Haren; A.L. Pendriks; S. PhiliCLASP2 is requ
ulos; W. van IJfespan and inh
. Phylactides; Aeja; F.G. Grosve causes Hered
SDD
SDE
DDC
SDP
; G.P. Patrinos;ne. 2012. ez; T.K. van de3 in platelet adhPereira; Z. Liu; Upsen; M. Momuired for hemat
cken; Z. Ozgür;ibiting erythro
A.J.M.H. Verkerkeld; M. von Linditary Persisten
SECRETARÍA DEDE INVESTIGACDESARROLLO E
SECRETARÍA GEDE CIENCIA, TECE INNOVACIÓN
DIRECCIÓN GENDE INVESTIGACCIENTÍFICA Y TÉ
SUBDIRECCIÓN DE RECURSOS HPARA LA INVEST
; S. Philipsen;
en Berg; T.W. hesion to collagU. Akinci; T. Nik
mmaas; F. Grosvtopoiesis and h
; S. Philipsen; Mopoiesis throug
k; P.J. van der Sndern; A.E. Felicnce of Fetal H
E ESTADO IÓN INNOVACIÓN
ENERAL CNOLOGÍA
NERAL IÓN
ÉCNICA
GENERAL HUMANOS TIGACIÓN
F. Grosveld. A
Kuijpers. Defecgen. Blood. 201kolic; W. van IJcveld; H. Maiatohematopoietic
M.A. Nolte. Chh an IRF1/PU1
Spek; C.A. Scerrce; G.P. PatrinoHemoglobin. Na
Dual
cts in 2. cken; o; J.E. stem
ronic ‐axis.
ri; W. os; S. ature