1
L L i i f f e e S S c c i i e e n n c c e e S S e e m m i i n n a a r r S S e e r r i i e e s s Thursday May 3, 2018 13.15 - 14.00 in Hörsal B (Bilbergska) Örebro University I I m m m m u u n n e e c c y y t t o o l l y y t t i i c c a a c c t t i i v v i i t t y y i i n n c c a a n n c c e e r r – – s s p p o o t t l l i i g g h h t t o o n n c c o o l l o o r r e e c c t t a a l l c c a a n n c c e e r r Assis. Prof. Apostolos Zaravinos Department of Life Sciences European University Cyprus Host: Jana Jass Dr. Zaravinos's research is focus is on the advanced understanding of carcinogenesis through the investigation of immune cytolytic activity. Immune cytolytic activity is determined by the expression of granzyme A and perforin 1, both being secreted by effector cytotoxic Tcells (CTL) and natural killer (NK) cells. High levels of these substances are exhibited upon CD8+ Tcell activation and during a productive clinical response against immune checkpoint blockade therapies.
